TreeWAS – Variant ID: rs3123636

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.996	0.004	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.995	0.005	0.000
I20-I25 Ischaemic heart diseases	0.991	0.009	0.000
C61 Malignant neoplasm of prostate	0.987	0.013	0.000
I20 Angina pectoris	0.956	0.044	0.000
I21 Acute myocardial infarction	0.956	0.044	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.951	0.049	0.000
I25.2 Old myocardial infarction	0.949	0.051	0.000
I20.0 Unstable angina	0.928	0.072	0.000
I22 Subsequent myocardial infarction	0.910	0.090	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.909	0.091	0.000
I20.9 Angina pectoris, unspecified	0.869	0.131	0.000
I25.4 Coronary artery aneurysm	0.869	0.131	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.763	0.237	0.000
I22.8 Subsequent myocardial infarction of other sites	0.757	0.243	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.739	0.261	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.729	0.271	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
I23 Certain current complications following acute myocardial infarction	0.715	0.285	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.686	0.314	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.664	0.336	0.000
I20.8 Other forms of angina pectoris	0.600	0.400	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.596	0.404	0.000
I21.9 Acute myocardial infarction, unspecified	0.592	0.408	0.000
I24 Other acute ischaemic heart diseases	0.567	0.433	0.000
I23.8 Other current complications following acute myocardial infarction	0.517	0.483	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.516	0.484	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.512	0.487	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.512	0.487	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.512	0.487	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.512	0.487	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.512	0.487	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.512	0.487	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.512	0.487	0.000
I25.5 Ischaemic cardiomyopathy	0.479	0.521	0.000
I24.1 Dressler's syndrome	0.457	0.543	0.000
I24.8 Other forms of acute ischaemic heart disease	0.457	0.543	0.000
I21.4 Acute subendocardial myocardial infarction	0.435	0.565	0.000
I20.1 Angina pectoris with documented spasm	0.408	0.592	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.400	0.600	0.000
I25.3 Aneurysm of heart	0.397	0.603	0.000
C60-C63 Malignant neoplasms of male genital organs	0.369	0.631	0.000
C63 Malignant neoplasm of other and unspecified male genital organs	0.266	0.734	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.264	0.735	0.000
C60 Malignant neoplasm of penis	0.256	0.744	0.000
C62 Malignant neoplasm of testis	0.252	0.748	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.250	0.750	0.000
Z95.1 Presence of aortocoronary bypass graft	0.243	0.757	0.000
Z95.3 Presence of xenogenic heart valve	0.227	0.773	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.225	0.774	0.000
C62.1 Descended testis	0.202	0.798	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.200	0.800	0.000
C63.2 Scrotum	0.192	0.808	0.000
C63.9 Male genital organ, unspecified	0.191	0.809	0.000
C63.8 Overlapping lesion of male genital organs	0.191	0.809	0.000
C63.7 Other specified male genital organs	0.191	0.809	0.000
C63.1 Spermatic cord	0.191	0.809	0.000
C63.0 Epididymis	0.191	0.809	0.000
C60.0 Prepuce	0.188	0.812	0.000
C60.8 Overlapping lesion of penis	0.183	0.816	0.000
C60.2 Body of penis	0.183	0.816	0.000
C60.1 Glans penis	0.183	0.816	0.000
C62.0 Undescended testis	0.181	0.819	0.000
C60.9 Penis, unspecified	0.169	0.831	0.000
Z95.0 Presence of cardiac pacemaker	0.146	0.854	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.136	0.864	0.000
C62.9 Testis, unspecified	0.132	0.868	0.000
K22.7 Barrett's oesophagus	0.094	0.906	0.000
E78.0 Pure hypercholesterolaemia	0.084	0.916	0.000
E11.9 Without complications	0.082	0.918	0.000
Z95.2 Presence of prosthetic heart valve	0.075	0.925	0.000
Z95.4 Presence of other heart-valve replacement	0.066	0.934	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.000	0.970	0.030
Z50.0 Cardiac rehabilitation	0.015	0.985	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.987	0.013
K22 Other diseases of oesophagus	0.013	0.987	0.000
K22.2 Oesophageal obstruction	0.012	0.988	0.000
K22.1 Ulcer of oesophagus	0.010	0.990	0.000
K22.0 Achalasia of cardia	0.010	0.990	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.991	0.009
K22.3 Perforation of oesophagus	0.009	0.991	0.000
M54.50 Low back pain (Multiple sites in spine)	0.000	0.992	0.008
I35.0 Aortic (valve) stenosis	0.008	0.992	0.000
E11.6 With other specified complications	0.008	0.992	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.992	0.008
K22.9 Disease of oesophagus, unspecified	0.008	0.992	0.000
K22.8 Other specified diseases of oesophagus	0.007	0.993	0.000
K83.0 Cholangitis	0.000	0.993	0.007
D04.5 Skin of trunk	0.007	0.993	0.000
E11 Non-insulin-dependent diabetes mellitus	0.007	0.993	0.000
L92.0 Granuloma annulare	0.000	0.993	0.007
K22.5 Diverticulum of oesophagus, acquired	0.007	0.993	0.000
O80.8 Other single spontaneous delivery	0.007	0.993	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.007	0.993	0.000
H60.1 Cellulitis of external ear	0.000	0.993	0.007
M25.51 Pain in joint (Shoulder region)	0.000	0.994	0.006
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.994	0.006
O80.0 Spontaneous vertex delivery	0.006	0.994	0.000
S22.30 Fracture of rib (closed)	0.000	0.994	0.006
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.000	0.994	0.006
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.000	0.994	0.006
F81.9 Developmental disorder of scholastic skills, unspecified	0.006	0.994	0.000
D04 Carcinoma in situ of skin	0.006	0.994	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.000	0.994	0.006
D04.3 Skin of other and unspecified parts of face	0.006	0.994	0.000
E11.4 With neurological complications	0.006	0.994	0.000
O80 Single spontaneous delivery	0.006	0.994	0.000
E11.7 With multiple complications	0.005	0.994	0.000
E78.2 Mixed hyperlipidaemia	0.005	0.995	0.000
E78.6 Lipoprotein deficiency	0.005	0.995	0.000
T31.0 Burns involving less than 10% of body surface	0.000	0.995	0.005
D04.1 Skin of eyelid, including canthus	0.005	0.995	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.005	0.995	0.000
D04.9 Skin, unspecified	0.005	0.995	0.000
D04.7 Skin of lower limb, including hip	0.005	0.995	0.000
E11.8 With unspecified complications	0.005	0.995	0.000
E78.3 Hyperchylomicronaemia	0.005	0.995	0.000
Q05.9 Spina bifida, unspecified	0.005	0.995	0.000
E11.1 With ketoacidosis	0.005	0.995	0.000
E78.4 Other hyperlipidaemia	0.005	0.995	0.000
H66.9 Otitis media, unspecified	0.005	0.995	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.005	0.995	0.000
D04.6 Skin of upper limb, including shoulder	0.005	0.995	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.000	0.995	0.005
D04.8 Skin of other sites	0.004	0.996	0.000
D04.0 Skin of lip	0.004	0.996	0.000
S22.3 Fracture of rib	0.000	0.996	0.004
C26.0 Intestinal tract, part unspecified	0.004	0.996	0.000
R17 Unspecified jaundice	0.004	0.996	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.004	0.996	0.000
O80.1 Spontaneous breech delivery	0.004	0.996	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.996	0.004
E11.0 With coma	0.004	0.996	0.000
E78.8 Other disorders of lipoprotein metabolism	0.004	0.996	0.000
F81 Specific developmental disorders of scholastic skills	0.004	0.996	0.000
E78.1 Pure hyperglyceridaemia	0.003	0.996	0.000
M81.4 Drug-induced osteoporosis	0.004	0.996	0.000
T31 Burns classified according to extent of body surface involved	0.000	0.996	0.004
D04.2 Skin of ear and external auricular canal	0.003	0.996	0.000
G30.0 Alzheimer's disease with early onset	0.000	0.996	0.003
M81.49 Drug-induced osteoporosis (Site unspecified)	0.003	0.996	0.000
S22.31 Fracture of rib (open)	0.000	0.997	0.003
I42.9 Cardiomyopathy, unspecified	0.000	0.997	0.003
J06.9 Acute upper respiratory infection, unspecified	0.003	0.997	0.000
S22.50 Flail chest (closed)	0.000	0.997	0.003
G30.9 Alzheimer's disease, unspecified	0.000	0.997	0.003
T31.1 Burns involving 10-19% of body surface	0.000	0.997	0.003
S22.5 Flail chest	0.000	0.997	0.003
H60 Otitis externa	0.000	0.997	0.003
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.997	0.003
O80-O84 Delivery	0.003	0.997	0.000
D04.4 Skin of scalp and neck	0.003	0.997	0.000
H60.5 Acute otitis externa, non-infective	0.000	0.997	0.003
R25.8 Other and unspecified abnormal involuntary movements	0.003	0.997	0.000
H60.3 Other infective otitis externa	0.000	0.997	0.003
G30 Alzheimer's disease	0.000	0.997	0.003
E11.2 With renal complications	0.003	0.997	0.000
R25.1 Tremor, unspecified	0.003	0.997	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.003	0.997	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.997	0.003
B18.2 Chronic viral hepatitis C	0.003	0.997	0.000
G93.0 Cerebral cysts	0.000	0.997	0.003
F81.8 Other developmental disorders of scholastic skills	0.003	0.997	0.000
F81.3 Mixed disorder of scholastic skills	0.003	0.997	0.000
F81.2 Specific disorder of arithmetical skills	0.003	0.997	0.000
F81.1 Specific spelling disorder	0.003	0.997	0.000
F81.0 Specific reading disorder	0.003	0.997	0.000
Q05 Spina bifida	0.003	0.997	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.997	0.003
E78.5 Hyperlipidaemia, unspecified	0.003	0.997	0.000
X10.0 Home	0.000	0.997	0.003
M81.48 Drug-induced osteoporosis (Other)	0.003	0.997	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.003	0.997	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.003	0.997	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.003	0.997	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.003	0.997	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.003	0.997	0.000
T31.9 Burns involving 90% or more of body surface	0.000	0.997	0.003
T31.8 Burns involving 80-89% of body surface	0.000	0.997	0.003
T31.7 Burns involving 70-79% of body surface	0.000	0.997	0.003
T31.6 Burns involving 60-69% of body surface	0.000	0.997	0.003
T31.5 Burns involving 50-59% of body surface	0.000	0.997	0.003
T31.4 Burns involving 40-49% of body surface	0.000	0.997	0.003
T31.3 Burns involving 30-39% of body surface	0.000	0.997	0.003
T31.2 Burns involving 20-29% of body surface	0.000	0.997	0.003
G30.8 Other Alzheimer's disease	0.000	0.997	0.003
N60.4 Mammary duct ectasia	0.003	0.997	0.000
G54.0 Brachial plexus disorders	0.000	0.997	0.003
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.997	0.003
O83 Other assisted single delivery	0.003	0.997	0.000
H60.8 Other otitis externa	0.000	0.997	0.003
I42.8 Other cardiomyopathies	0.000	0.997	0.003
K22.4 Dyskinesia of oesophagus	0.003	0.997	0.000
O84 Multiple delivery	0.003	0.997	0.000
R25 Abnormal involuntary movements	0.003	0.997	0.000
G93.9 Disorder of brain, unspecified	0.000	0.997	0.003
M81.2 Osteoporosis of disuse	0.003	0.997	0.000
O36.8 Maternal care for other specified foetal problems	0.003	0.997	0.000
O82 Single delivery by Caesarean section	0.003	0.997	0.000
O81 Single delivery by forceps and vacuum extractor	0.003	0.997	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.003	0.997	0.000
G40 Epilepsy	0.000	0.997	0.003
G30.1 Alzheimer's disease with late onset	0.000	0.997	0.003
I35.9 Aortic valve disorder, unspecified	0.003	0.997	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.997	0.003
S22.51 Flail chest (open)	0.000	0.997	0.002
H60.2 Malignant otitis externa	0.000	0.997	0.002
R25.3 Fasciculation	0.003	0.997	0.000
S22.9 Fracture of bony thorax, part unspecified	0.000	0.997	0.002
S22.8 Fracture of other parts of bony thorax	0.000	0.997	0.002
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.000	0.997	0.003
K04.8 Radicular cyst	0.003	0.997	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.002	0.997	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.002	0.997	0.000
O82.1 Delivery by emergency Caesarean section	0.003	0.997	0.000
O83.1 Other assisted breech delivery	0.002	0.997	0.000
O81.4 Vacuum extractor delivery	0.002	0.997	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.002	0.998	0.000
I35 Nonrheumatic aortic valve disorders	0.002	0.998	0.000
S22.01 Fracture of thoracic vertebra (open)	0.000	0.998	0.002
M81.3 Postsurgical malabsorption osteoporosis	0.002	0.998	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.998	0.002
S22.1 Multiple fractures of thoracic spine	0.000	0.998	0.002
I42 Cardiomyopathy	0.000	0.998	0.002
M81 Osteoporosis without pathological fracture	0.002	0.998	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.998	0.002
Q05.8 Sacral spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.002	0.998	0.000
G40.8 Other epilepsy	0.000	0.998	0.002
K56.7 Ileus, unspecified	0.000	0.998	0.002
S22.4 Multiple fractures of ribs	0.000	0.998	0.002
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.998	0.002
M47.80 Other spondylosis (Multiple sites in spine)	0.002	0.998	0.000
H60.0 Abscess of external ear	0.000	0.998	0.002
I42.2 Other hypertrophic cardiomyopathy	0.000	0.998	0.002
O83.9 Assisted single delivery, unspecified	0.002	0.998	0.000
O83.8 Other specified assisted single delivery	0.002	0.998	0.000
O83.4 Destructive operation for delivery	0.002	0.998	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.002	0.998	0.000
O83.2 Other manipulation-assisted delivery	0.002	0.998	0.000
O83.0 Breech extraction	0.002	0.998	0.000
T20.1 Burn of first degree of head and neck	0.000	0.998	0.002
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.998	0.002
H60.4 Cholesteatoma of external ear	0.000	0.998	0.002
K56.4 Other impaction of intestine	0.000	0.998	0.002
O69.8 Labour and delivery complicated by other cord complications	0.000	0.998	0.002
O84.2 Multiple delivery, all by Caesarean section	0.002	0.998	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.998	0.002
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.998	0.002
K56.0 Paralytic ileus	0.000	0.998	0.002
S22.2 Fracture of sternum	0.000	0.998	0.002
G93.5 Compression of brain	0.000	0.998	0.002
R25.0 Abnormal head movements	0.002	0.998	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.002	0.998	0.000
M81.28 Osteoporosis of disuse (Other)	0.002	0.998	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.002	0.998	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.002	0.998	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.002	0.998	0.000
M81.24 Osteoporosis of disuse (Hand)	0.002	0.998	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.002	0.998	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.002	0.998	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.002	0.998	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.002	0.998	0.000
O81.2 Mid-cavity forceps with rotation	0.002	0.998	0.000
O81.1 Mid-cavity forceps delivery	0.002	0.998	0.000
O82.8 Other single delivery by Caesarean section	0.002	0.998	0.000
O82.2 Delivery by Caesarean hysterectomy	0.002	0.998	0.000
O84.9 Multiple delivery, unspecified	0.002	0.998	0.000
O84.8 Other multiple delivery	0.002	0.998	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.002	0.998	0.000
O84.0 Multiple delivery, all spontaneous	0.002	0.998	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.998	0.002
G93 Other disorders of brain	0.000	0.998	0.002
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.998	0.002
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.998	0.002
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.998	0.002
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.998	0.002
B44.1 Other pulmonary aspergillosis	0.000	0.998	0.002
M41.9 Scoliosis, unspecified	0.000	0.998	0.002
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.998	0.002
G40.5 Special epileptic syndromes	0.000	0.998	0.002
L20.9 Atopic dermatitis, unspecified	0.002	0.998	0.000
O36.6 Maternal care for excessive foetal growth	0.002	0.998	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.998	0.002
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.998	0.002
K56 Paralytic ileus and intestinal obstruction without hernia	0.000	0.998	0.002
O81.3 Other and unspecified forceps delivery	0.002	0.998	0.000
F80-F89 Disorders of psychological development	0.002	0.998	0.000
O81.0 Low forceps delivery	0.002	0.998	0.000
S70.1 Contusion of thigh	0.000	0.998	0.002
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.002	0.998	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.002	0.998	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.002	0.998	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.002	0.998	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.002	0.998	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.002	0.998	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.998	0.002
G93.2 Benign intracranial hypertension	0.000	0.998	0.002
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.998	0.002
K59.8 Other specified functional intestinal disorders	0.002	0.998	0.000
M81.8 Other osteoporosis	0.002	0.998	0.000
M81.6 Localised osteoporosis [Lequesne]	0.002	0.998	0.000
M81.5 Idiopathic osteoporosis	0.002	0.998	0.000
M81.1 Postoophorectomy osteoporosis	0.002	0.998	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.998	0.002
S22.41 Multiple fractures of ribs (open)	0.000	0.998	0.002
M81.0 Postmenopausal osteoporosis	0.002	0.998	0.000
O82.9 Delivery by Caesarean section, unspecified	0.002	0.998	0.000
O82.0 Delivery by elective Caesarean section	0.002	0.998	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.998	0.002
B44.9 Aspergillosis, unspecified	0.000	0.998	0.002
O80.9 Single spontaneous delivery, unspecified	0.002	0.998	0.000
C15.5 Lower third of oesophagus	0.002	0.998	0.000
F80 Specific developmental disorders of speech and language	0.002	0.998	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.002	0.998	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.002	0.998	0.000
F80.1 Expressive language disorder	0.002	0.998	0.000
G41.9 Status epilepticus, unspecified	0.000	0.998	0.002
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
S22.21 Fracture of sternum (open)	0.000	0.998	0.002
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.998	0.002
K74.0 Hepatic fibrosis	0.000	0.998	0.002
C26 Malignant neoplasm of other and ill-defined digestive organs	0.002	0.998	0.000
F00 Dementia in Alzheimer's disease	0.000	0.998	0.002
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.998	0.002
G93.7 Reye's syndrome	0.000	0.998	0.002
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.998	0.002
G95.9 Disease of spinal cord, unspecified	0.000	0.998	0.002
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
C02.9 Tongue, unspecified	0.002	0.998	0.000
E11.5 With peripheral circulatory complications	0.001	0.998	0.001
I42.5 Other restrictive cardiomyopathy	0.000	0.998	0.002
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.000	0.998	0.002
I42.4 Endocardial fibroelastosis	0.000	0.998	0.002
S19.9 Unspecified injury of neck	0.002	0.998	0.000
T20 Burn and corrosion of head and neck	0.000	0.998	0.002
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.998	0.002
S52.20 Fracture of shaft of ulna (closed)	0.000	0.998	0.002
D73.5 Infarction of spleen	0.002	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.998	0.002
K12.1 Other forms of stomatitis	0.002	0.998	0.000
R25.2 Cramp and spasm	0.002	0.998	0.000
Z58.1 Exposure to air pollution	0.000	0.998	0.002
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.002
T36.0 Penicillins	0.002	0.998	0.000
F84 Pervasive developmental disorders	0.002	0.998	0.000
F89 Unspecified disorder of psychological development	0.002	0.998	0.000
F88 Other disorders of psychological development	0.002	0.998	0.000
F83 Mixed specific developmental disorders	0.002	0.998	0.000
F82 Specific developmental disorder of motor function	0.002	0.998	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.998	0.002
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.998	0.002
G93.8 Other specified disorders of brain	0.000	0.998	0.002
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.001	0.998	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.001	0.998	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.001	0.998	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.001	0.998	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.001	0.998	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.001	0.998	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.001	0.998	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.001	0.998	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.001	0.998	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.001	0.998	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.001	0.998	0.000
M81.58 Idiopathic osteoporosis (Other)	0.001	0.998	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.001	0.998	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.001	0.998	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.001	0.998	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.001	0.998	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.001	0.998	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.001	0.998	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.001	0.998	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.001	0.998	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.001	0.998	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.001	0.998	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.001	0.998	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.001	0.998	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.001	0.998	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.001	0.998	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.001	0.998	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.001	0.998	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.001	0.998	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.001	0.998	0.000
M81.89 Other osteoporosis (Site unspecified)	0.001	0.998	0.000
M81.88 Other osteoporosis (Other)	0.001	0.998	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.001	0.998	0.000
M81.86 Other osteoporosis (Lower leg)	0.001	0.998	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.001	0.998	0.000
M81.84 Other osteoporosis (Hand)	0.001	0.998	0.000
M81.83 Other osteoporosis (Forearm)	0.001	0.998	0.000
M81.82 Other osteoporosis (Upper arm)	0.001	0.998	0.000
M81.81 Other osteoporosis (Shoulder region)	0.001	0.998	0.000
M81.80 Other osteoporosis (Multiple sites)	0.001	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
T20.0 Burn of unspecified degree of head and neck	0.000	0.998	0.002
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
X10 Contact with hot drinks, food, fats and cooking oils	0.000	0.998	0.002
M81.08 Postmenopausal osteoporosis (Other)	0.001	0.998	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.001	0.998	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.001	0.998	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.001	0.998	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.001	0.998	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.001	0.998	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.001	0.998	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.001	0.998	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.001	0.998	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
O36 Maternal care for other known or suspected foetal problems	0.002	0.998	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.998	0.002
F80.9 Developmental disorder of speech and language, unspecified	0.001	0.998	0.000
F80.8 Other developmental disorders of speech and language	0.001	0.998	0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.001	0.998	0.000
F80.2 Receptive language disorder	0.001	0.998	0.000
F80.0 Specific speech articulation disorder	0.001	0.998	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.002	0.998	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.998	0.002
I42.6 Alcoholic cardiomyopathy	0.000	0.998	0.002
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.001	0.998	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.998	0.002
S22.40 Multiple fractures of ribs (closed)	0.000	0.998	0.002
C26.8 Overlapping lesion of digestive system	0.001	0.998	0.000
C26.1 Spleen	0.001	0.998	0.000
F84.0 Childhood autism	0.001	0.998	0.000
G40.9 Epilepsy, unspecified	0.000	0.998	0.002
K56.3 Gallstone ileus	0.000	0.998	0.001
B44 Aspergillosis	0.000	0.998	0.002
M41.92 Scoliosis, unspecified (Cervical region)	0.000	0.998	0.001
G72.9 Myopathy, unspecified	0.002	0.998	0.000
G95.2 Cord compression, unspecified	0.000	0.998	0.002
C26.9 Ill-defined sites within the digestive system	0.001	0.998	0.000
C82.2 Large cell, follicular	0.000	0.998	0.002
H43.8 Other disorders of vitreous body	0.000	0.998	0.002
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.002	0.998	0.000
O36.5 Maternal care for poor foetal growth	0.002	0.998	0.000
T20.7 Corrosion of third degree of head and neck	0.000	0.998	0.001
T20.6 Corrosion of second degree of head and neck	0.000	0.998	0.001
T20.5 Corrosion of first degree of head and neck	0.000	0.998	0.001
T20.4 Corrosion of unspecified degree of head and neck	0.000	0.998	0.001
T20.3 Burn of third degree of head and neck	0.000	0.998	0.001
G54 Nerve root and plexus disorders	0.000	0.998	0.002
M06.37 Rheumatoid nodule (Ankle and foot)	0.002	0.998	0.000
G54.6 Phantom limb syndrome with pain	0.000	0.998	0.001
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.001	0.998	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.001
B18 Chronic viral hepatitis	0.002	0.998	0.000
F84.9 Pervasive developmental disorder, unspecified	0.001	0.998	0.000
F84.8 Other pervasive developmental disorders	0.001	0.998	0.000
F84.4 Overactive disorder associated with mental retardation and stereotyped movements	0.001	0.998	0.000
F84.3 Other childhood disintegrative disorder	0.001	0.998	0.000
F84.2 Rett's syndrome	0.001	0.998	0.000
F84.1 Atypical autism	0.001	0.998	0.000
H54.7 Unspecified visual loss	0.002	0.998	0.000
I42.0 Dilated cardiomyopathy	0.000	0.998	0.002
L30.8 Other specified dermatitis	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.001	0.998	0.000
G72.8 Other specified myopathies	0.001	0.998	0.000
X10.9 Unspecified place	0.000	0.998	0.001
X10.8 Other specified place	0.000	0.998	0.001
X10.7 Farm	0.000	0.998	0.001
X10.6 Industrial and construction area	0.000	0.998	0.001
X10.5 Trade and service area	0.000	0.998	0.001
X10.4 Street and highway	0.000	0.998	0.001
X10.3 Sports and athletics area	0.000	0.998	0.001
X10.2 School, other institution and public administrative area	0.000	0.998	0.001
X10.1 Residential institution	0.000	0.998	0.001
G72 Other myopathies	0.002	0.998	0.000
G93.4 Encephalopathy, unspecified	0.000	0.998	0.001
N48.6 Balanitis xerotica obliterans	0.000	0.998	0.002
O36.2 Maternal care for hydrops foetalis	0.001	0.998	0.000
O36.1 Maternal care for other isoimmunisation	0.001	0.998	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.001	0.998	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.001
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.001
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.001
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.001
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.001
G72.0 Drug-induced myopathy	0.001	0.999	0.000
O36.9 Maternal care for foetal problem, unspecified	0.001	0.999	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.999	0.001
E11.3 With ophthalmic complications	0.001	0.999	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.999	0.001
O36.4 Maternal care for intra-uterine death	0.001	0.999	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.999	0.001
S91.3 Open wound of other parts of foot	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations