TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs3129106
log Bayes Factor = 64.8301
Chromosome 6   position 29,081,161  (GRCh37) Explore rs3129106 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.011 0.989
E10 Insulin-dependent diabetes mellitus
0.000 0.037 0.963
E10.9 Without complications
0.000 0.038 0.962
E10.3 With ophthalmic complications
0.000 0.069 0.931
E10.2 With renal complications
0.000 0.113 0.887
L40.9 Psoriasis, unspecified
0.000 0.114 0.886
L40.5 Arthropathic psoriasis
0.000 0.117 0.883
L40 Psoriasis
0.000 0.119 0.881
E10-E14 Diabetes mellitus
0.000 0.120 0.880
E13 Other specified diabetes mellitus
0.000 0.157 0.843
E10.4 With neurological complications
0.000 0.165 0.835
E13.9 Without complications
0.000 0.177 0.823
E10.0 With coma
0.000 0.238 0.762
E10.1 With ketoacidosis
0.000 0.248 0.752
E11 Non-insulin-dependent diabetes mellitus
0.000 0.257 0.743
E10.6 With other specified complications
0.000 0.266 0.734
E10.5 With peripheral circulatory complications
0.000 0.299 0.701
E10.7 With multiple complications
0.000 0.310 0.690
E11.6 With other specified complications
0.000 0.328 0.672
E11.4 With neurological complications
0.000 0.364 0.636
E14 Unspecified diabetes mellitus
0.000 0.366 0.633
L40.4 Guttate psoriasis
0.000 0.368 0.632
L40.3 Pustulosis palmaris et plantaris
0.000 0.368 0.632
L40.2 Acrodermatitis continua
0.000 0.368 0.632
L40.1 Generalised pustular psoriasis
0.000 0.368 0.632
E12 Malnutrition-related diabetes mellitus
0.000 0.369 0.631
L40.8 Other psoriasis
0.000 0.372 0.628
L40.0 Psoriasis vulgaris
0.000 0.378 0.622
E13.8 With unspecified complications
0.000 0.395 0.605
E13.7 With multiple complications
0.000 0.395 0.605
E13.6 With other specified complications
0.000 0.395 0.605
E13.5 With peripheral circulatory complications
0.000 0.395 0.605
E13.4 With neurological complications
0.000 0.395 0.605
E13.2 With renal complications
0.000 0.395 0.605
E13.1 With ketoacidosis
0.000 0.395 0.605
E13.0 With coma
0.000 0.395 0.605
E11.0 With coma
0.000 0.406 0.594
E11.5 With peripheral circulatory complications
0.000 0.407 0.593
E11.2 With renal complications
0.000 0.416 0.584
K90 Intestinal malabsorption
0.000 0.419 0.581
E10.8 With unspecified complications
0.000 0.434 0.566
E13.3 With ophthalmic complications
0.000 0.451 0.549
E11.7 With multiple complications
0.000 0.467 0.532
E11.1 With ketoacidosis
0.000 0.490 0.510
E11.8 With unspecified complications
0.000 0.500 0.500
E14.9 Without complications
0.000 0.505 0.495
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.521 0.479
E14.8 With unspecified complications
0.000 0.530 0.469
E14.7 With multiple complications
0.000 0.546 0.454
E14.6 With other specified complications
0.000 0.546 0.454
E14.5 With peripheral circulatory complications
0.000 0.546 0.454
E14.4 With neurological complications
0.000 0.546 0.454
E14.2 Withrenal complications
0.000 0.546 0.454
E14.1 With ketoacidosis
0.000 0.546 0.454
E14.0 With coma
0.000 0.546 0.454
E12.9 Without complications
0.000 0.548 0.452
E12.8 With unspecified complications
0.000 0.548 0.452
E12.7 With multiple complications
0.000 0.548 0.452
E12.6 With other specified complications
0.000 0.548 0.452
E12.5 With peripheral circulatory complications
0.000 0.548 0.452
E12.4 With neurological complications
0.000 0.548 0.452
E12.3 With ophthalmic complications
0.000 0.548 0.452
E12.2 With renal complications
0.000 0.548 0.452
E12.1 With ketoacidosis
0.000 0.548 0.452
E12.0 With coma
0.000 0.548 0.452
K90.9 Intestinal malabsorption, unspecified
0.000 0.574 0.426
K90.8 Other intestinal malabsorption
0.000 0.576 0.423
K90.3 Pancreatic steatorrhoea
0.000 0.583 0.417
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.583 0.417
K90.1 Tropical sprue
0.000 0.583 0.417
E14.3 With ophthalmic complications
0.000 0.615 0.385
E11.3 With ophthalmic complications
0.000 0.645 0.355
L40-L45 Papulosquamous disorders
0.000 0.691 0.309
L43 Lichen planus
0.000 0.768 0.232
L44 Other papulosquamous disorders
0.000 0.778 0.222
L41 Parapsoriasis
0.000 0.778 0.222
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.778 0.222
L43.8 Other lichen planus
0.000 0.797 0.203
L42 Pityriasis rosea
0.000 0.822 0.177
L43.3 Subacute (active) lichen planus
0.000 0.834 0.166
L43.2 Lichenoid drug reaction
0.000 0.834 0.166
L43.1 Bullous lichen planus
0.000 0.834 0.166
L43.0 Hypertrophic lichen planus
0.000 0.834 0.166
L41.9 Parapsoriasis, unspecified
0.000 0.841 0.159
L41.8 Other parapsoriasis
0.000 0.841 0.159
L41.5 Retiform parapsoriasis
0.000 0.841 0.159
L41.4 Large plaque parapsoriasis
0.000 0.841 0.159
L41.3 Small plaque parapsoriasis
0.000 0.841 0.159
L41.2 Lymphomatoid papulosis
0.000 0.841 0.159
L41.1 Pityriasis lichenoides chronica
0.000 0.841 0.159
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.841 0.159
L44.9 Papulosquamous disorder, unspecified
0.000 0.841 0.159
L44.8 Other specified papulosquamous disorders
0.000 0.841 0.159
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.841 0.159
L44.3 Lichen ruber moniliformis
0.000 0.841 0.159
L44.2 Lichen striatus
0.000 0.841 0.159
L44.1 Lichen nitidus
0.000 0.841 0.159
L44.0 Pityriasis rubra pilaris
0.000 0.841 0.159
E83 Disorders of mineral metabolism
0.117 0.867 0.016
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.872 0.128
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.874 0.126
E16 Other disorders of pancreatic internal secretion
0.000 0.876 0.124
E16.2 Hypoglycaemia, unspecified
0.000 0.877 0.123
E11.9 Without complications
0.000 0.892 0.108
L43.9 Lichen planus, unspecified
0.000 0.894 0.106
E40-E46 Malnutrition
0.000 0.897 0.103
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.099 0.901 0.000
E16.1 Other hypoglycaemia
0.000 0.902 0.098
E83.3 Disorders of phosphorus metabolism
0.092 0.902 0.007
E83.9 Disorder of mineral metabolism, unspecified
0.084 0.905 0.011
E83.8 Other disorders of mineral metabolism
0.084 0.905 0.011
E83.2 Disorders of zinc metabolism
0.084 0.905 0.011
E83.0 Disorders of copper metabolism
0.084 0.905 0.011
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.905 0.094
E15 Nondiabetic hypoglycaemic coma
0.000 0.910 0.090
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.911 0.089
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.911 0.089
E16.4 Abnormal secretion of gastrin
0.000 0.911 0.089
E16.3 Increased secretion of glucagon
0.000 0.911 0.089
E46 Unspecified protein-energy malnutrition
0.000 0.915 0.085
E50-E64 Other nutritional deficiencies
0.000 0.919 0.081
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.926 0.074
E45 Retarded development following protein-energy malnutrition
0.000 0.926 0.074
E43 Unspecified severe protein-energy malnutrition
0.000 0.926 0.074
E42 Marasmic kwashiorkor
0.000 0.926 0.074
E41 Nutritional marasmus
0.000 0.926 0.074
E40 Kwashiorkor
0.000 0.926 0.074
E55 Vitamin D deficiency
0.000 0.939 0.061
K90-K93 Other diseases of the digestive system
0.000 0.940 0.060
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.941 0.058
E63 Other nutritional deficiencies
0.000 0.941 0.058
E56 Other vitamin deficiencies
0.000 0.941 0.058
E51 Thiamine deficiency
0.000 0.941 0.058
E50 Vitamin A deficiency
0.000 0.941 0.058
E60 Dietary zinc deficiency
0.000 0.941 0.058
E59 Dietary selenium deficiency
0.000 0.941 0.058
E54 Ascorbic acid deficiency
0.000 0.941 0.058
E52 Niacin deficiency [pellagra]
0.000 0.941 0.058
E61 Deficiency of other nutrient elements
0.000 0.942 0.058
E58 Dietary calcium deficiency
0.000 0.945 0.055
E44.1 Mild protein-energy malnutrition
0.000 0.946 0.053
E44.0 Moderate protein-energy malnutrition
0.000 0.946 0.053
G35 Multiple sclerosis
0.053 0.947 0.000
E83.4 Disorders of magnesium metabolism
0.043 0.947 0.010
E53 Deficiency of other B group vitamins
0.000 0.952 0.048
E55.9 Vitamin D deficiency, unspecified
0.000 0.953 0.047
E20-E35 Disorders of other endocrine glands
0.000 0.954 0.046
E55.0 Rickets, active
0.000 0.956 0.044
I83 Varicose veins of lower extremities
0.044 0.956 0.000
E61.2 Magnesium deficiency
0.000 0.956 0.044
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.956 0.043
E65-E68 Obesity and other hyperalimentation
0.000 0.957 0.042
E50.9 Vitamin A deficiency, unspecified
0.000 0.958 0.042
E50.8 Other manifestations of vitamin A deficiency
0.000 0.958 0.042
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.958 0.042
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.958 0.042
E50.5 Vitamin A deficiency with night blindness
0.000 0.958 0.042
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.958 0.042
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.958 0.042
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.958 0.042
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.958 0.042
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.958 0.042
E51.9 Thiamine deficiency, unspecified
0.000 0.958 0.042
E51.8 Other manifestations of thiamine deficiency
0.000 0.958 0.042
E51.2 Wernicke's encephalopathy
0.000 0.958 0.042
E51.1 Beriberi
0.000 0.958 0.042
E56.9 Vitamin deficiency, unspecified
0.000 0.958 0.042
E56.8 Deficiency of other vitamins
0.000 0.958 0.042
E56.1 Deficiency of vitamin K
0.000 0.958 0.042
E56.0 Deficiency of vitamin E
0.000 0.958 0.042
E63.9 Nutritional deficiency, unspecified
0.000 0.958 0.042
E63.8 Other specified nutritional deficiencies
0.000 0.958 0.042
E63.1 Imbalance of constituents of food intake
0.000 0.958 0.042
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.958 0.042
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.958 0.042
E64.8 Sequelae of other nutritional deficiencies
0.000 0.958 0.042
E64.3 Sequelae of rickets
0.000 0.958 0.042
E64.2 Sequelae of vitamin C deficiency
0.000 0.958 0.042
E64.1 Sequelae of vitamin A deficiency
0.000 0.958 0.042
E64.0 Sequelae of protein-energy malnutrition
0.000 0.958 0.042
E61.9 Deficiency of nutrient element, unspecified
0.000 0.958 0.041
E61.8 Deficiency of other specified nutrient elements
0.000 0.958 0.041
E61.7 Deficiency of multiple nutrient elements
0.000 0.958 0.041
E61.6 Vanadium deficiency
0.000 0.958 0.041
E61.5 Molybdenum deficiency
0.000 0.958 0.041
E61.4 Chromium deficiency
0.000 0.958 0.041
E61.3 Manganese deficiency
0.000 0.958 0.041
E61.0 Copper deficiency
0.000 0.958 0.041
E24 Cushing's syndrome
0.000 0.960 0.040
E20 Hypoparathyroidism
0.000 0.962 0.038
E61.1 Iron deficiency
0.000 0.962 0.038
E53.9 Vitamin B deficiency, unspecified
0.000 0.963 0.037
I83.0 Varicose veins of lower extremities with ulcer
0.037 0.963 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.963 0.037
E78.0 Pure hypercholesterolaemia
0.000 0.964 0.036
E70-E90 Metabolic disorders
0.001 0.965 0.034
E53.1 Pyridoxine deficiency
0.000 0.965 0.035
E53.0 Riboflavin deficiency
0.000 0.965 0.035
H43.8 Other disorders of vitreous body
0.000 0.966 0.034
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.966 0.034
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.967 0.033
E32 Diseases of thymus
0.000 0.967 0.033
E31 Polyglandular dysfunction
0.000 0.967 0.033
E30 Disorders of puberty, not elsewhere classified
0.000 0.967 0.033
E25 Adrenogenital disorders
0.000 0.967 0.033
E20.9 Hypoparathyroidism, unspecified
0.000 0.967 0.033
E34 Other endocrine disorders
0.000 0.968 0.032
E22 Hyperfunction of pituitary gland
0.000 0.968 0.032
E28 Ovarian dysfunction
0.000 0.968 0.032
E78.2 Mixed hyperlipidaemia
0.000 0.968 0.032
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.968 0.031
K93.1 Megacolon in Chagas' disease
0.000 0.968 0.031
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.968 0.031
E67 Other hyperalimentation
0.000 0.969 0.031
E68 Sequelae of hyperalimentation
0.000 0.969 0.031
I83.1 Varicose veins of lower extremities with inflammation
0.031 0.969 0.000
E24.8 Other Cushing's syndrome
0.000 0.971 0.029
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.971 0.029
E24.3 Ectopic ACTH syndrome
0.000 0.971 0.029
E24.2 Drug-induced Cushing's syndrome
0.000 0.971 0.029
E24.1 Nelson's syndrome
0.000 0.971 0.029
E24.0 Pituitary-dependent Cushing's disease
0.000 0.971 0.029
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.971 0.029
E85 Amyloidosis
0.001 0.971 0.028
E26 Hyperaldosteronism
0.000 0.971 0.028
E29 Testicular dysfunction
0.000 0.972 0.028
E20.8 Other hypoparathyroidism
0.000 0.972 0.028
E20.1 Pseudohypoparathyroidism
0.000 0.972 0.028
E20.0 Idiopathic hypoparathyroidism
0.000 0.972 0.028
K91.3 Postoperative intestinal obstruction
0.000 0.972 0.028
E23 Hypofunction and other disorders of pituitary gland
0.000 0.973 0.027
E00-E07 Disorders of thyroid gland
0.000 0.973 0.027
E88 Other metabolic disorders
0.001 0.973 0.026
E78.1 Pure hyperglyceridaemia
0.000 0.973 0.027
E22.0 Acromegaly and pituitary gigantism
0.000 0.973 0.027
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.026 0.974 0.000
E74 Other disorders of carbohydrate metabolism
0.001 0.974 0.025
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.974 0.026
E79 Disorders of purine and pyrimidine metabolism
0.001 0.975 0.024
E77 Disorders of glycoprotein metabolism
0.001 0.975 0.024
E76 Disorders of glycosaminoglycan metabolism
0.001 0.975 0.024
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.975 0.024
E72 Other disorders of amino-acid metabolism
0.001 0.975 0.024
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.975 0.024
E70 Disorders of aromatic amino-acid metabolism
0.001 0.975 0.024
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.975 0.024
E78.6 Lipoprotein deficiency
0.000 0.975 0.025
E78.3 Hyperchylomicronaemia
0.000 0.975 0.025
E84 Cystic fibrosis
0.001 0.975 0.024
E28.2 Polycystic ovarian syndrome
0.000 0.976 0.024
E85.4 Organ-limited amyloidosis
0.000 0.976 0.024
E25.9 Adrenogenital disorder, unspecified
0.000 0.976 0.024
E25.8 Other adrenogenital disorders
0.000 0.976 0.024
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.976 0.024
E30.9 Disorder of puberty, unspecified
0.000 0.976 0.024
E30.8 Other disorders of puberty
0.000 0.976 0.024
E30.1 Precocious puberty
0.000 0.976 0.024
E30.0 Delayed puberty
0.000 0.976 0.024
E31.9 Polyglandular dysfunction, unspecified
0.000 0.976 0.024
E31.8 Other polyglandular dysfunction
0.000 0.976 0.024
E31.1 Polyglandular hyperfunction
0.000 0.976 0.024
E31.0 Autoimmune polyglandular failure
0.000 0.976 0.024
E32.9 Disease of thymus, unspecified
0.000 0.976 0.024
E32.8 Other diseases of thymus
0.000 0.976 0.024
E32.1 Abscess of thymus
0.000 0.976 0.024
E32.0 Persistent hyperplasia of thymus
0.000 0.976 0.024
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.976 0.024
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.976 0.024
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.976 0.024
E34.9 Endocrine disorder, unspecified
0.000 0.976 0.024
E78.8 Other disorders of lipoprotein metabolism
0.000 0.976 0.024
E34.5 Androgen resistance syndrome
0.000 0.976 0.023
E34.4 Constitutional tall stature
0.000 0.976 0.023
E34.3 Short stature, not elsewhere classified
0.000 0.976 0.023
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.976 0.023
E34.1 Other hypersecretion of intestinal hormones
0.000 0.976 0.023
E73 Lactose intolerance
0.001 0.977 0.022
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.977 0.023
E22.8 Other hyperfunction of pituitary gland
0.000 0.977 0.023
E28.9 Ovarian dysfunction, unspecified
0.000 0.977 0.023
E28.8 Other ovarian dysfunction
0.000 0.977 0.023
E28.1 Androgen excess
0.000 0.977 0.023
E28.0 Oestrogen excess
0.000 0.977 0.023
E78.4 Other hyperlipidaemia
0.000 0.977 0.023
H40.2 Primary angle-closure glaucoma
0.023 0.977 0.000
E34.8 Other specified endocrine disorders
0.000 0.977 0.023
E34.0 Carcinoid syndrome
0.000 0.977 0.023
E65 Localised adiposity
0.000 0.977 0.022
E67.8 Other specified hyperalimentation
0.000 0.978 0.022
E67.3 Hypervitaminosis D
0.000 0.978 0.022
E67.2 Megavitamin-B6 syndrome
0.000 0.978 0.022
E67.1 Hypercarotenaemia
0.000 0.978 0.022
E67.0 Hypervitaminosis A
0.000 0.978 0.022
E83.5 Disorders of calcium metabolism
0.010 0.978 0.012
E85.3 Secondary systemic amyloidosis
0.001 0.978 0.021
E23.7 Disorder of pituitary gland, unspecified
0.000 0.978 0.021
K91.1 Postgastric surgery syndromes
0.000 0.979 0.021
H43 Disorders of vitreous body
0.000 0.979 0.021
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.979 0.021
E88.2 Lipomatosis, not elsewhere classified
0.000 0.979 0.021
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.979 0.021
K91.4 Colostomy and enterostomy malfunction
0.000 0.979 0.021
E85.8 Other amyloidosis
0.001 0.979 0.020
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.979 0.020
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.979 0.020
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.979 0.020
E26.9 Hyperaldosteronism, unspecified
0.000 0.979 0.021
E26.8 Other hyperaldosteronism
0.000 0.979 0.021
E26.1 Secondary hyperaldosteronism
0.000 0.979 0.021
E28.3 Primary ovarian failure
0.000 0.980 0.020
E29.9 Testicular dysfunction, unspecified
0.000 0.980 0.020
E29.8 Other testicular dysfunction
0.000 0.980 0.020
E29.0 Testicular hyperfunction
0.000 0.980 0.020
E21.3 Hyperparathyroidism, unspecified
0.000 0.980 0.020
E85.9 Amyloidosis, unspecified
0.001 0.980 0.019
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.980 0.020
E23.1 Drug-induced hypopituitarism
0.000 0.980 0.020
E53.8 Deficiency of other specified B group vitamins
0.000 0.980 0.020
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.980 0.020
E00 Congenital iodine-deficiency syndrome
0.000 0.980 0.020
E23.2 Diabetes insipidus
0.000 0.980 0.020
E88.9 Metabolic disorder, unspecified
0.001 0.980 0.019
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.980 0.019
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.980 0.019
K91.5 Postcholecystectomy syndrome
0.000 0.981 0.019
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.981 0.019
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.981 0.019
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.981 0.019
E22.1 Hyperprolactinaemia
0.000 0.981 0.019
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.981 0.019
E07 Other disorders of thyroid
0.000 0.981 0.019
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.981 0.018
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.981 0.018
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.981 0.018
E74.2 Disorders of galactose metabolism
0.001 0.981 0.018
E74.1 Disorders of fructose metabolism
0.001 0.981 0.018
E74.0 Glycogen storage disease
0.001 0.981 0.018
E88.8 Other specified metabolic disorders
0.001 0.981 0.018
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.981 0.019
E21.4 Other specified disorders of parathyroid gland
0.000 0.981 0.019
E21.2 Other hyperparathyroidism
0.000 0.981 0.019
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.981 0.019
E88.3 Tumour lysis syndrome
0.001 0.981 0.018
E06 Thyroiditis
0.000 0.981 0.018
G35-G37 Demyelinating diseases of the central nervous system
0.019 0.981 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.981 0.018
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.981 0.018
E70.3 Albinism
0.001 0.981 0.018
E70.2 Disorders of tyrosine metabolism
0.001 0.981 0.018
E70.1 Other hyperphenylalaninaemias
0.001 0.981 0.018
E70.0 Classical phenylketonuria
0.001 0.981 0.018
E71.3 Disorders of fatty-acid metabolism
0.001 0.981 0.018
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.981 0.018
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.981 0.018
E71.0 Maple-syrup-urine disease
0.001 0.981 0.018
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.981 0.018
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.981 0.018
E72.5 Disorders of glycine metabolism
0.001 0.981 0.018
E72.4 Disorders of ornithine metabolism
0.001 0.981 0.018
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.981 0.018
E72.2 Disorders of urea cycle metabolism
0.001 0.981 0.018
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.981 0.018
E72.0 Disorders of amino-acid transport
0.001 0.981 0.018
E75.6 Lipid storage disorder, unspecified
0.001 0.981 0.018
E75.5 Other lipid storage disorders
0.001 0.981 0.018
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.981 0.018
E75.3 Sphingolipidosis, unspecified
0.001 0.981 0.018
E75.2 Other sphingolipidosis
0.001 0.981 0.018
E75.1 Other gangliosidosis
0.001 0.981 0.018
E75.0 GM2 gangliosidosis
0.001 0.981 0.018
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.981 0.018
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.981 0.018
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.981 0.018
E76.2 Other mucopolysaccharidoses
0.001 0.981 0.018
E76.1 Mucopolysaccharidosis, type II
0.001 0.981 0.018
E76.0 Mucopolysaccharidosis, type I
0.001 0.981 0.018
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.981 0.018
E77.8 Other disorders of glycoprotein metabolism
0.001 0.981 0.018
E77.1 Defects in glycoprotein degradation
0.001 0.981 0.018
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.981 0.018
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.981 0.018
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.981 0.018
E79.1 Lesch-Nyhan syndrome
0.001 0.981 0.018
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.981 0.018
E84.8 Cystic fibrosis with other manifestations
0.001 0.982 0.017
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.982 0.017
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.982 0.017
E84.9 Cystic fibrosis, unspecified
0.001 0.983 0.016
E73.8 Other lactose intolerance
0.001 0.983 0.016
E73.1 Secondary lactase deficiency
0.001 0.983 0.016
E73.0 Congenital lactase deficiency
0.001 0.983 0.016
H43.9 Disorder of vitreous body, unspecified
0.000 0.983 0.017
E06.9 Thyroiditis, unspecified
0.000 0.983 0.016
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.983 0.016
H43.3 Other vitreous opacities
0.000 0.984 0.016
E23.6 Other disorders of pituitary gland
0.000 0.984 0.016
H43.2 Crystalline deposits in vitreous body
0.000 0.984 0.016
E26.0 Primary hyperaldosteronism
0.000 0.984 0.016
E05.8 Other thyrotoxicosis
0.000 0.984 0.016
E23.0 Hypopituitarism
0.000 0.984 0.016
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.984 0.016
H43.0 Vitreous prolapse
0.000 0.985 0.015
E78.5 Hyperlipidaemia, unspecified
0.000 0.985 0.015
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.985 0.014
E73.9 Lactose intolerance, unspecified
0.001 0.985 0.014
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.985 0.015
C43.5 Malignant melanoma of trunk
0.000 0.985 0.015
E29.1 Testicular hypofunction
0.000 0.985 0.014
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.986 0.014
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.986 0.014
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.986 0.014
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.986 0.014
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.986 0.014
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.986 0.014
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.986 0.014
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.986 0.014
E07.8 Other specified disorders of thyroid
0.000 0.986 0.014
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.986 0.014
E05.5 Thyroid crisis or storm
0.000 0.986 0.014
E05.4 Thyrotoxicosis factitia
0.000 0.986 0.014
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.986 0.014
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.986 0.014
E07.1 Dyshormogenetic goitre
0.000 0.986 0.014
E07.0 Hypersecretion of calcitonin
0.000 0.986 0.014
E06.5 Other chronic thyroiditis
0.000 0.986 0.013
E06.4 Drug-induced thyroiditis
0.000 0.986 0.013
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.986 0.013
E06.1 Subacute thyroiditis
0.000 0.986 0.013
E06.0 Acute thyroiditis
0.000 0.986 0.013
H43.1 Vitreous haemorrhage
0.000 0.986 0.014
G36 Other acute disseminated demyelination
0.013 0.986 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.986 0.014
C43 Malignant melanoma of skin
0.000 0.987 0.013
E07.9 Disorder of thyroid, unspecified
0.000 0.987 0.013
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.988 0.012
G37 Other demyelinating diseases of central nervous system
0.011 0.989 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.989 0.010
E80.5 Crigler-Najjar syndrome
0.001 0.989 0.010
E80.3 Defects of catalase and peroxydase
0.001 0.989 0.010
E80.0 Hereditary erythropoietic porphyria
0.001 0.989 0.010
E80.2 Other porphyria
0.001 0.989 0.010
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.989 0.011
E80.6 Other disorders of bilirubin metabolism
0.001 0.989 0.010
Z87.8 Personal history of other specified conditions
0.010 0.990 0.000
G36.9 Acute disseminated demyelination, unspecified
0.010 0.990 0.000
G36.8 Other specified acute disseminated demyelination
0.010 0.990 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.010 0.990 0.000
G36.0 Neuromyelitis optica [Devic]
0.010 0.990 0.000
E03 Other hypothyroidism
0.000 0.990 0.010
C43.8 Overlapping malignant melanoma of skin
0.000 0.990 0.010
C43.0 Malignant melanoma of lip
0.000 0.990 0.010
C43.4 Malignant melanoma of scalp and neck
0.000 0.991 0.009
C43.9 Malignant melanoma of skin, unspecified
0.000 0.991 0.009
G37.8 Other specified demyelinating diseases of central nervous system
0.009 0.991 0.000
F10.0 Acute intoxication
0.009 0.991 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.000 0.991 0.009
F10.1 Harmful use
0.009 0.991 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.009 0.991 0.000
E80.1 Porphyria cutanea tarda
0.001 0.991 0.007
E27 Other disorders of adrenal gland
0.000 0.992 0.008
G37.5 Concentric sclerosis [Balo]
0.008 0.992 0.000
G37.4 Subacute necrotising myelitis
0.008 0.992 0.000
G37.2 Central pontine myelinolysis
0.008 0.992 0.000
G37.1 Central demyelination of corpus callosum
0.008 0.992 0.000
G37.0 Diffuse sclerosis
0.008 0.992 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.008 0.992 0.000
F10.2 Dependence syndrome
0.008 0.992 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.992 0.008
F10.5 Psychotic disorder
0.008 0.992 0.000
M75.0 Adhesive capsulitis of shoulder
0.000 0.993 0.007
H43-H45 Disorders of vitreous body and globe
0.000 0.993 0.007
E03.8 Other specified hypothyroidism
0.000 0.993 0.007
E80.4 Gilbert's syndrome
0.001 0.993 0.007
E03.5 Myxoedema coma
0.000 0.993 0.007
E03.4 Atrophy of thyroid (acquired)
0.000 0.993 0.007
E03.3 Postinfectious hypothyroidism
0.000 0.993 0.007
E03.1 Congenital hypothyroidism without goitre
0.000 0.993 0.007
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.993 0.007
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.001 0.993 0.006
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.993 0.007
H40 Glaucoma
0.007 0.993 0.000
E21.0 Primary hyperparathyroidism
0.000 0.993 0.006
F10.7 Residual and late-onset psychotic disorder
0.007 0.993 0.000
H40.5 Glaucoma secondary to other eye disorders
0.007 0.993 0.000
F10.8 Other mental and behavioural disorders
0.006 0.994 0.000
K04.5 Chronic apical periodontitis
0.006 0.994 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.994 0.006
E27.5 Adrenomedullary hyperfunction
0.000 0.994 0.006
E27.0 Other adrenocortical overactivity
0.000 0.994 0.006
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.994 0.006
M07.3 Other psoriatic arthropathies
0.000 0.994 0.006
F10.9 Unspecified mental and behavioural disorder
0.006 0.994 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.994 0.006
E66 Obesity
0.000 0.994 0.006
F10.3 Withdrawal state
0.006 0.994 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.994 0.005
Q89.2 Congenital malformations of other endocrine glands
0.006 0.994 0.000
F10.6 Amnesic syndrome
0.006 0.994 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.994 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2025 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.