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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129889
log Bayes Factor = 208.68
Chromosome 6   position 32,413,545  (GRCh37) Explore rs3129889 on Ensembl!
Variant rs3129889 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.001 0.999
Chapter XI Diseases of the digestive system
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.002 0.998
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.002 0.000
K90-K93 Other diseases of the digestive system
0.000 0.002 0.998
G37 Other demyelinating diseases of central nervous system
0.998 0.002 0.000
J33 Nasal polyp
0.000 0.002 0.998
J33.9 Nasal polyp, unspecified
0.000 0.002 0.998
G37.9 Demyelinating disease of central nervous system, unspecified
0.997 0.003 0.000
I10 Essential (primary) hypertension
0.000 0.004 0.996
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.004 0.996
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.004 0.996
J45 Asthma
0.000 0.004 0.996
J40-J47 Chronic lower respiratory diseases
0.000 0.005 0.995
Chapter X Diseases of the respiratory system
0.000 0.005 0.995
E14.3 With ophthalmic complications
0.000 0.006 0.994
K70-K77 Diseases of liver
0.000 0.006 0.994
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.007 0.993
K51.3 Ulcerative (chronic) rectosigmoiditis
0.993 0.007 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.007 0.993
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.009 0.991
E70-E90 Metabolic disorders
0.000 0.010 0.990
H43-H45 Disorders of vitreous body and globe
0.000 0.011 0.989
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.012 0.988
H40-H42 Glaucoma
0.000 0.014 0.986
H43 Disorders of vitreous body
0.000 0.015 0.985
J30-J39 Other diseases of upper respiratory tract
0.000 0.015 0.985
I20 Angina pectoris
0.000 0.015 0.985
I22 Subsequent myocardial infarction
0.000 0.018 0.982
E05.9 Thyrotoxicosis, unspecified
0.000 0.022 0.978
E10.5 With peripheral circulatory complications
0.000 0.023 0.977
K74 Fibrosis and cirrhosis of liver
0.000 0.024 0.976
H40 Glaucoma
0.000 0.024 0.976
H40.9 Glaucoma, unspecified
0.000 0.027 0.973
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.029 0.971
E11.3 With ophthalmic complications
0.000 0.030 0.970
J33.8 Other polyp of sinus
0.000 0.030 0.970
K51.8 Other ulcerative colitis
0.962 0.038 0.000
E11.1 With ketoacidosis
0.000 0.039 0.961
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.039 0.961
L40-L45 Papulosquamous disorders
0.000 0.040 0.960
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.041 0.959
E06 Thyroiditis
0.000 0.042 0.958
L43 Lichen planus
0.000 0.043 0.957
L40 Psoriasis
0.000 0.044 0.956
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.045 0.955
L43.9 Lichen planus, unspecified
0.000 0.046 0.954
H43.3 Other vitreous opacities
0.000 0.046 0.954
I12 Hypertensive renal disease
0.000 0.049 0.951
H43.8 Other disorders of vitreous body
0.000 0.050 0.950
K74.3 Primary biliary cirrhosis
0.000 0.054 0.946
J33.0 Polyp of nasal cavity
0.000 0.056 0.944
L40.5 Arthropathic psoriasis
0.000 0.056 0.944
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.056 0.943
I25 Chronic ischaemic heart disease
0.000 0.062 0.938
K50-K52 Noninfective enteritis and colitis
0.016 0.064 0.920
E06.3 Autoimmune thyroiditis
0.000 0.069 0.931
E10.2 With renal complications
0.000 0.075 0.925
E11.5 With peripheral circulatory complications
0.000 0.077 0.923
I20.0 Unstable angina
0.000 0.079 0.921
I20.1 Angina pectoris with documented spasm
0.000 0.079 0.921
M70-M79 Other soft tissue disorders
0.000 0.079 0.921
I20.9 Angina pectoris, unspecified
0.000 0.080 0.920
H34 Retinal vascular occlusions
0.000 0.080 0.920
J46 Status asthmaticus
0.000 0.082 0.918
E13 Other specified diabetes mellitus
0.000 0.084 0.916
K55-K64 Other diseases of intestines
0.000 0.098 0.902
K51.2 Ulcerative (chronic) proctitis
0.901 0.099 0.000
K72 Hepatic failure, not elsewhere classified
0.000 0.100 0.900
M06.0 Seronegative rheumatoid arthritis
0.000 0.106 0.894
I12.9 Hypertensive renal disease without renal failure
0.000 0.106 0.894
E11.2 With renal complications
0.000 0.107 0.893
K60 Fissure and fistula of anal and rectal regions
0.000 0.108 0.892
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.110 0.890
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.110 0.890
Chapter VIII Diseases of the ear and mastoid process
0.000 0.113 0.887
H25-H28 Disorders of lens
0.000 0.113 0.887
E11.6 With other specified complications
0.000 0.118 0.882
E07 Other disorders of thyroid
0.000 0.119 0.881
M75 Shoulder lesions
0.000 0.122 0.878
E03.8 Other specified hypothyroidism
0.000 0.123 0.877
H60-H62 Diseases of external ear
0.000 0.126 0.874
K50 Crohn's disease [regional enteritis]
0.001 0.126 0.873
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.127 0.873
I25.5 Ischaemic cardiomyopathy
0.000 0.128 0.872
I15 Secondary hypertension
0.000 0.134 0.866
H61 Other disorders of external ear
0.000 0.137 0.863
J44 Other chronic obstructive pulmonary disease
0.000 0.137 0.863
H40.1 Primary open-angle glaucoma
0.000 0.138 0.862
L40.9 Psoriasis, unspecified
0.000 0.139 0.861
M77 Other enthesopathies
0.000 0.140 0.860
M75.0 Adhesive capsulitis of shoulder
0.000 0.143 0.857
E13.9 Without complications
0.000 0.145 0.855
K60.2 Anal fissure, unspecified
0.000 0.145 0.855
M77.1 Lateral epicondylitis
0.000 0.149 0.851
I24 Other acute ischaemic heart diseases
0.000 0.149 0.851
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.153 0.847
K75 Other inflammatory liver diseases
0.000 0.153 0.847
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.155 0.845
K60.0 Acute anal fissure
0.000 0.162 0.838
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.163 0.837
H61.0 Perichondritis of external ear
0.000 0.163 0.837
M06.4 Inflammatory polyarthropathy
0.000 0.164 0.836
K58 Irritable bowel syndrome
0.000 0.165 0.835
I25.2 Old myocardial infarction
0.000 0.165 0.835
G37.8 Other specified demyelinating diseases of central nervous system
0.834 0.166 0.000
K73 Chronic hepatitis, not elsewhere classified
0.000 0.173 0.827
K74.6 Other and unspecified cirrhosis of liver
0.000 0.175 0.825
H27 Other disorders of lens
0.000 0.176 0.824
M65-M68 Disorders of synovium and tendon
0.000 0.177 0.823
J86 Pyothorax
0.000 0.178 0.822
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.179 0.821
J32 Chronic sinusitis
0.000 0.182 0.818
K60.5 Anorectal fistula
0.000 0.184 0.816
J43 Emphysema
0.000 0.184 0.816
K74.5 Biliary cirrhosis, unspecified
0.000 0.185 0.815
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.815 0.185 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.187 0.813
M07 Psoriatic and enteropathic arthropathies
0.000 0.188 0.812
E07.9 Disorder of thyroid, unspecified
0.000 0.188 0.812
K51.4 Pseudopolyposis of colon
0.811 0.189 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.192 0.808
K55 Vascular disorders of intestine
0.000 0.192 0.808
M06.3 Rheumatoid nodule
0.000 0.193 0.807
H40.5 Glaucoma secondary to other eye disorders
0.000 0.193 0.807
H34.2 Other retinal artery occlusions
0.000 0.195 0.805
E88 Other metabolic disorders
0.000 0.201 0.799
K50.8 Other Crohn's disease
0.000 0.202 0.798
K75.4 Autoimmune hepatitis
0.000 0.202 0.798
E40-E46 Malnutrition
0.000 0.202 0.798
K72.9 Hepatic failure, unspecified
0.000 0.207 0.793
E78.1 Pure hyperglyceridaemia
0.000 0.209 0.791
K51.5 Mucosal proctocolitis
0.790 0.210 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.215 0.785
H25 Senile cataract
0.000 0.215 0.785
J37 Chronic laryngitis and laryngotracheitis
0.000 0.215 0.785
E78.5 Hyperlipidaemia, unspecified
0.000 0.216 0.784
E16.1 Other hypoglycaemia
0.000 0.218 0.782
M75.2 Bicipital tendinitis
0.000 0.219 0.781
M45-M49 Spondylopathies
0.000 0.219 0.781
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.221 0.779
H25.1 Senile nuclear cataract
0.000 0.221 0.779
E78.2 Mixed hyperlipidaemia
0.000 0.224 0.776
M14 Arthropathies in other diseases classified elsewhere
0.000 0.224 0.776
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.226 0.774
K50.1 Crohn's disease of large intestine
0.000 0.227 0.773
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.227 0.773
E74 Other disorders of carbohydrate metabolism
0.000 0.227 0.773
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.230 0.770
I15.1 Hypertension secondary to other renal disorders
0.000 0.230 0.770
M45 Ankylosing spondylitis
0.000 0.233 0.767
I23 Certain current complications following acute myocardial infarction
0.000 0.235 0.765
L43.8 Other lichen planus
0.000 0.236 0.764
H34.8 Other retinal vascular occlusions
0.000 0.237 0.763
H43.1 Vitreous haemorrhage
0.000 0.238 0.762
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.241 0.758
I25.1 Atherosclerotic heart disease
0.000 0.249 0.751
K63 Other diseases of intestine
0.000 0.255 0.745
M65 Synovitis and tenosynovitis
0.000 0.256 0.744
H43.2 Crystalline deposits in vitreous body
0.000 0.257 0.743
K72.0 Acute and subacute hepatic failure
0.000 0.258 0.742
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.259 0.741
H61.8 Other specified disorders of external ear
0.000 0.259 0.741
K90.9 Intestinal malabsorption, unspecified
0.000 0.262 0.738
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.264 0.736
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.265 0.735
H61.1 Non-infective disorders of pinna
0.000 0.266 0.734
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.266 0.734
M11 Other crystal arthropathies
0.000 0.268 0.732
K55.2 Angiodysplasia of colon
0.000 0.269 0.731
E11.8 With unspecified complications
0.000 0.270 0.729
J86.9 Pyothorax without fistula
0.000 0.271 0.729
K51.0 Ulcerative (chronic) enterocolitis
0.729 0.271 0.000
H43.9 Disorder of vitreous body, unspecified
0.000 0.274 0.726
L40.8 Other psoriasis
0.000 0.274 0.726
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.279 0.721
H34.1 Central retinal artery occlusion
0.000 0.280 0.720
H40.4 Glaucoma secondary to eye inflammation
0.000 0.280 0.720
E11.4 With neurological complications
0.000 0.281 0.719
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
K51.1 Ulcerative (chronic) ileocolitis
0.717 0.283 0.000
I13 Hypertensive heart and renal disease
0.000 0.283 0.716
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
G36 Other acute disseminated demyelination
0.715 0.284 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
G37.5 Concentric sclerosis [Balo]
0.715 0.284 0.000
G37.4 Subacute necrotising myelitis
0.715 0.284 0.000
G37.2 Central pontine myelinolysis
0.715 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.715 0.284 0.000
G37.0 Diffuse sclerosis
0.715 0.284 0.000
J33.1 Polypoid sinus degeneration
0.000 0.285 0.715
K63.9 Disease of intestine, unspecified
0.000 0.285 0.715
H27.0 Aphakia
0.000 0.285 0.715
J45.8 Mixed asthma
0.000 0.286 0.714
J45.1 Nonallergic asthma
0.000 0.286 0.714
H30 Chorioretinal inflammation
0.000 0.286 0.714
M75.3 Calcific tendinitis of shoulder
0.000 0.287 0.713
K77 Liver disorders in diseases classified elsewhere
0.000 0.288 0.712
K71 Toxic liver disease
0.000 0.288 0.712
E78.6 Lipoprotein deficiency
0.000 0.288 0.712
E78.3 Hyperchylomicronaemia
0.000 0.288 0.712
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.288 0.712
E77 Disorders of glycoprotein metabolism
0.000 0.290 0.710
E76 Disorders of glycosaminoglycan metabolism
0.000 0.290 0.710
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.290 0.710
E72 Other disorders of amino-acid metabolism
0.000 0.290 0.710
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.290 0.710
E70 Disorders of aromatic amino-acid metabolism
0.000 0.290 0.710
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.290 0.710
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.291 0.709
E05.5 Thyroid crisis or storm
0.000 0.292 0.708
E05.4 Thyrotoxicosis factitia
0.000 0.292 0.708
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.292 0.708
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.292 0.708
H42 Glaucoma in diseases classified elsewhere
0.000 0.293 0.707
H43.0 Vitreous prolapse
0.000 0.293 0.707
I11 Hypertensive heart disease
0.000 0.294 0.706
E11.0 With coma
0.000 0.297 0.703
H27.8 Other specified disorders of lens
0.000 0.298 0.702
J86.0 Pyothorax with fistula
0.000 0.298 0.702
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.300 0.700
K74.4 Secondary biliary cirrhosis
0.000 0.300 0.700
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.300 0.700
K74.1 Hepatic sclerosis
0.000 0.300 0.700
H40.6 Glaucoma secondary to drugs
0.000 0.300 0.699
H40.3 Glaucoma secondary to eye trauma
0.000 0.300 0.699
M75.4 Impingement syndrome of shoulder
0.000 0.301 0.699
K55.8 Other vascular disorders of intestine
0.000 0.305 0.695
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.305 0.695
J41 Simple and mucopurulent chronic bronchitis
0.000 0.309 0.691
H61.3 Acquired stenosis of external ear canal
0.000 0.311 0.689
J32.4 Chronic pansinusitis
0.000 0.311 0.689
L44 Other papulosquamous disorders
0.000 0.311 0.689
L41 Parapsoriasis
0.000 0.311 0.689
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.311 0.689
E06.5 Other chronic thyroiditis
0.000 0.313 0.687
E06.4 Drug-induced thyroiditis
0.000 0.313 0.687
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.313 0.687
E06.1 Subacute thyroiditis
0.000 0.313 0.687
E06.0 Acute thyroiditis
0.000 0.313 0.687
L43.3 Subacute (active) lichen planus
0.000 0.314 0.686
L43.2 Lichenoid drug reaction
0.000 0.314 0.686
L43.1 Bullous lichen planus
0.000 0.314 0.686
L43.0 Hypertrophic lichen planus
0.000 0.314 0.686
L40.4 Guttate psoriasis
0.000 0.315 0.685
L40.3 Pustulosis palmaris et plantaris
0.000 0.315 0.685
L40.2 Acrodermatitis continua
0.000 0.315 0.685
L40.1 Generalised pustular psoriasis
0.000 0.315 0.685
I25.4 Coronary artery aneurysm
0.000 0.316 0.684
K73.9 Chronic hepatitis, unspecified
0.000 0.317 0.683
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.317 0.683
K82 Other diseases of gallbladder
0.000 0.319 0.681
M12 Other specific arthropathies
0.000 0.320 0.680
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.321 0.679
E05.8 Other thyrotoxicosis
0.000 0.321 0.678
M07.3 Other psoriatic arthropathies
0.000 0.322 0.678
J32.9 Chronic sinusitis, unspecified
0.000 0.322 0.678
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.325 0.675
K76 Other diseases of liver
0.000 0.325 0.675
K52 Other non-infective gastro-enteritis and colitis
0.003 0.327 0.671
M76 Enthesopathies of lower limb, excluding foot
0.000 0.327 0.673
I25.6 Silent myocardial ischaemia
0.000 0.327 0.673
L40.0 Psoriasis vulgaris
0.000 0.327 0.673
K63.3 Ulcer of intestine
0.000 0.331 0.669
K50.0 Crohn's disease of small intestine
0.000 0.333 0.667
K82.8 Other specified diseases of gallbladder
0.000 0.334 0.666
E06.9 Thyroiditis, unspecified
0.000 0.335 0.665
M14.6 Neuropathic arthropathy
0.000 0.336 0.663
H60 Otitis externa
0.000 0.337 0.663
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.337 0.663
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.338 0.662
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.340 0.660
E84 Cystic fibrosis
0.000 0.340 0.660
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.340 0.660
H34.0 Transient retinal artery occlusion
0.000 0.340 0.660
E13.8 With unspecified complications
0.000 0.343 0.656
E13.7 With multiple complications
0.000 0.343 0.656
E13.6 With other specified complications
0.000 0.343 0.656
E13.5 With peripheral circulatory complications
0.000 0.343 0.656
E13.4 With neurological complications
0.000 0.343 0.656
E13.3 With ophthalmic complications
0.000 0.343 0.656
E13.2 With renal complications
0.000 0.343 0.656
E13.1 With ketoacidosis
0.000 0.343 0.656
E13.0 With coma
0.000 0.343 0.656
K76.8 Other specified diseases of liver
0.000 0.344 0.656
M06.34 Rheumatoid nodule (Hand)
0.000 0.346 0.654
E46 Unspecified protein-energy malnutrition
0.000 0.347 0.653
M72 Fibroblastic disorders
0.000 0.353 0.647
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.353 0.647
K72.1 Chronic hepatic failure
0.000 0.354 0.646
J43.9 Emphysema, unspecified
0.000 0.355 0.645
I25.3 Aneurysm of heart
0.000 0.356 0.644
J43.2 Centrilobular emphysema
0.000 0.358 0.642
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.358 0.642
H34.9 Retinal vascular occlusion, unspecified
0.000 0.358 0.642
J37.0 Chronic laryngitis
0.000 0.359 0.641
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.359 0.641
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.359 0.641
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.359 0.641
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.359 0.641
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.359 0.641
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.359 0.641
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.359 0.641
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.359 0.641
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.359 0.641
H27.1 Dislocation of lens
0.000 0.360 0.640
E79 Disorders of purine and pyrimidine metabolism
0.000 0.363 0.637
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.364 0.636
M10 Gout
0.000 0.365 0.635
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.366 0.634
E07.1 Dyshormogenetic goitre
0.000 0.368 0.632
E07.0 Hypersecretion of calcitonin
0.000 0.368 0.632
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.370 0.630
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.370 0.630
M75.8 Other shoulder lesions
0.000 0.370 0.630
L42 Pityriasis rosea
0.000 0.372 0.628
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.373 0.627
E83 Disorders of mineral metabolism
0.407 0.376 0.217
J95-J99 Other diseases of the respiratory system
0.000 0.377 0.623
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.377 0.623
E78.8 Other disorders of lipoprotein metabolism
0.000 0.377 0.623
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.377 0.623
K63.4 Enteroptosis
0.000 0.379 0.621
I15.9 Seconday hypertension, unspecified
0.000 0.379 0.621
I15.8 Other secondary hypertension
0.000 0.379 0.621
I15.2 Hypertension secondary to endocrine disorders
0.000 0.379 0.621
I15.0 Renovascular hypertension
0.000 0.379 0.621
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.381 0.619
L10-L14 Bullous disorders
0.000 0.382 0.618
J32.8 Other chronic sinusitis
0.000 0.382 0.618
K75.9 Inflammatory liver disease, unspecified
0.000 0.383 0.617
I21 Acute myocardial infarction
0.000 0.383 0.617
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.383 0.617
M77.8 Other enthesopathies, not elsewhere classified
0.000 0.383 0.617
M77.3 Calcaneal spur
0.000 0.383 0.617
M77.2 Periarthritis of wrist
0.000 0.383 0.617
E88.2 Lipomatosis, not elsewhere classified
0.000 0.384 0.615
K74.0 Hepatic fibrosis
0.000 0.387 0.613
J31.2 Chronic pharyngitis
0.000 0.389 0.611
J85 Abscess of lung and mediastinum
0.000 0.389 0.611
M77.19 Lateral epicondylitis (Site unspecified)
0.000 0.390 0.610
M77.18 Lateral epicondylitis-Other
0.000 0.390 0.610
M77.17 Lateral epicondylitis-Ankle/Foot
0.000 0.390 0.610
M77.16 Lateral epicondylitis (Lower leg)
0.000 0.390 0.610
M77.15 Lateral epicondylitis (Pelvic region and thigh)
0.000 0.390 0.610
M77.14 Lateral epicondylitis-Hand
0.000 0.390 0.610
M77.13 Lateral epicondylitis-Forearm
0.000 0.390 0.610
M77.11 Lateral epicondylitis-Shldr region
0.000 0.390 0.610
M77.10 Lateral epicondylitis (Multiple sites)
0.000 0.390 0.610
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.390 0.610
K55.1 Chronic vascular disorders of intestine
0.000 0.390 0.610
K52.1 Toxic gastro-enteritis and colitis
0.001 0.392 0.607
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.393 0.607
K75.2 Nonspecific reactive hepatitis
0.000 0.393 0.607
K75.1 Phlebitis of portal vein
0.000 0.393 0.607
E73 Lactose intolerance
0.000 0.393 0.607
H65-H75 Diseases of middle ear and mastoid
0.000 0.396 0.604
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.398 0.602
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.400 0.599
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.400 0.599
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.400 0.599
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.400 0.599
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.400 0.599
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.400 0.599
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.400 0.599
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.400 0.599
H35 Other retinal disorders
0.000 0.401 0.599
I23.8 Other current complications following acute myocardial infarction
0.000 0.403 0.597
M77.5 Other enthesopathy of foot
0.000 0.405 0.595
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.407 0.593
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.407 0.593
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.407 0.593
K91.3 Postoperative intestinal obstruction
0.000 0.407 0.593
M60-M63 Disorders of muscles
0.000 0.408 0.592
H27.9 Disorder of lens, unspecified
0.000 0.409 0.591
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.410 0.590
H61.9 Disorder of external ear, unspecified
0.000 0.411 0.589
K82.1 Hydrops of gallbladder
0.000 0.413 0.587
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.414 0.586
M49 Spondylopathies in diseases classified elsewhere
0.000 0.414 0.586
J32.1 Chronic frontal sinusitis
0.000 0.415 0.585
J43.8 Other emphysema
0.000 0.415 0.585
J43.1 Panlobular emphysema
0.000 0.415 0.585
J43.0 MacLeod's syndrome
0.000 0.415 0.585
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.415 0.585
J42 Unspecified chronic bronchitis
0.000 0.416 0.584
M07.6 Other enteropathic arthropathies
0.000 0.417 0.582
M07.5 Arthropathy in ulcerative colitis
0.000 0.417 0.582
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.417 0.582
M07.2 Psoriatic spondylitis
0.000 0.417 0.582
M07.1 Arthritis mutilans
0.000 0.417 0.582
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.417 0.582
K60.1 Chronic anal fissure
0.000 0.418 0.582
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.421 0.579
M06.38 Rheumatoid nodule (Other)
0.000 0.421 0.579
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.421 0.579
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.421 0.579
M06.33 Rheumatoid nodule (Forearm)
0.000 0.421 0.579
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.421 0.579
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.421 0.579
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.421 0.579
K90.8 Other intestinal malabsorption
0.000 0.423 0.577
M00-M03 Infectious arthropathies
0.000 0.423 0.576
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.423 0.577
M91-M94 Chondropathies
0.000 0.424 0.576
M86-M90 Other osteopathies
0.001 0.424 0.575
E07.8 Other specified disorders of thyroid
0.000 0.427 0.573
E88.9 Metabolic disorder, unspecified
0.000 0.427 0.573
E88.8 Other specified metabolic disorders
0.000 0.427 0.573
E88.3 Tumour lysis syndrome
0.000 0.427 0.573
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.427 0.573

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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