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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130056
log Bayes Factor = 65.3727
Chromosome 6   position 31,499,354  (GRCh37) Explore rs3130056 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.001 0.999
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.004 0.996
I20 Angina pectoris
0.000 0.005 0.995
E14.3 With ophthalmic complications
0.000 0.010 0.990
E14.9 Without complications
0.000 0.012 0.988
E10.1 With ketoacidosis
0.000 0.012 0.988
I25.5 Ischaemic cardiomyopathy
0.000 0.013 0.987
I20.9 Angina pectoris, unspecified
0.000 0.015 0.985
I22 Subsequent myocardial infarction
0.000 0.018 0.982
E10.4 With neurological complications
0.000 0.018 0.982
I20.0 Unstable angina
0.000 0.030 0.970
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.031 0.969
I25.2 Old myocardial infarction
0.000 0.031 0.969
G35-G37 Demyelinating diseases of the central nervous system
0.966 0.034 0.000
E83.1 Disorders of iron metabolism
0.962 0.038 0.000
I21 Acute myocardial infarction
0.000 0.039 0.961
G37 Other demyelinating diseases of central nervous system
0.960 0.040 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.044 0.956
G37.9 Demyelinating disease of central nervous system, unspecified
0.943 0.057 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.065 0.935
E13 Other specified diabetes mellitus
0.000 0.070 0.930
I10 Essential (primary) hypertension
0.000 0.071 0.929
E70-E90 Metabolic disorders
0.000 0.072 0.927
I21.9 Acute myocardial infarction, unspecified
0.000 0.074 0.926
R07.4 Chest pain, unspecified
0.000 0.107 0.893
I24 Other acute ischaemic heart diseases
0.000 0.107 0.893
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.110 0.890
L40-L45 Papulosquamous disorders
0.000 0.112 0.888
E78.8 Other disorders of lipoprotein metabolism
0.000 0.113 0.887
E10.2 With renal complications
0.000 0.117 0.883
E13.9 Without complications
0.000 0.119 0.881
E11.2 With renal complications
0.000 0.122 0.878
E11.0 With coma
0.000 0.133 0.867
L43 Lichen planus
0.000 0.137 0.863
I10-I15 Hypertensive diseases
0.000 0.151 0.849
I25.3 Aneurysm of heart
0.000 0.152 0.848
E00-E07 Disorders of thyroid gland
0.000 0.153 0.847
L40.8 Other psoriasis
0.000 0.158 0.842
I21.4 Acute subendocardial myocardial infarction
0.000 0.158 0.842
G37.8 Other specified demyelinating diseases of central nervous system
0.842 0.158 0.000
E11.1 With ketoacidosis
0.000 0.163 0.837
L43.9 Lichen planus, unspecified
0.000 0.164 0.836
E14.4 With neurological complications
0.000 0.175 0.825
E10.8 With unspecified complications
0.000 0.179 0.821
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.182 0.818
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.184 0.816
E03 Other hypothyroidism
0.000 0.190 0.810
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.195 0.805
E10.5 With peripheral circulatory complications
0.000 0.200 0.800
E03.9 Hypothyroidism, unspecified
0.000 0.202 0.798
E10.0 With coma
0.000 0.205 0.794
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.209 0.791
E78.2 Mixed hyperlipidaemia
0.000 0.210 0.790
L40.0 Psoriasis vulgaris
0.000 0.218 0.782
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.781 0.219 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.223 0.777
I23 Certain current complications following acute myocardial infarction
0.000 0.224 0.776
E85 Amyloidosis
0.000 0.225 0.775
E11.6 With other specified complications
0.000 0.228 0.772
E05.9 Thyrotoxicosis, unspecified
0.000 0.240 0.760
I15 Secondary hypertension
0.000 0.252 0.748
I24.8 Other forms of acute ischaemic heart disease
0.000 0.254 0.746
E78.6 Lipoprotein deficiency
0.000 0.263 0.737
E10.6 With other specified complications
0.000 0.265 0.735
E16 Other disorders of pancreatic internal secretion
0.000 0.265 0.735
E14.5 With peripheral circulatory complications
0.000 0.265 0.734
E74 Other disorders of carbohydrate metabolism
0.000 0.276 0.724
E14.6 With other specified complications
0.000 0.278 0.722
I12 Hypertensive renal disease
0.000 0.279 0.721
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E78.1 Pure hyperglyceridaemia
0.000 0.292 0.708
L43.8 Other lichen planus
0.000 0.293 0.707
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.295 0.705
E11.5 With peripheral circulatory complications
0.000 0.295 0.705
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.302 0.698
G36 Other acute disseminated demyelination
0.696 0.304 0.000
E78.3 Hyperchylomicronaemia
0.000 0.305 0.695
L40.3 Pustulosis palmaris et plantaris
0.000 0.305 0.695
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.311 0.689
G37.5 Concentric sclerosis [Balo]
0.688 0.312 0.000
G37.4 Subacute necrotising myelitis
0.688 0.312 0.000
G37.2 Central pontine myelinolysis
0.688 0.312 0.000
G37.1 Central demyelination of corpus callosum
0.688 0.312 0.000
G37.0 Diffuse sclerosis
0.688 0.312 0.000
I15.1 Hypertension secondary to other renal disorders
0.000 0.321 0.679
E13.8 With unspecified complications
0.000 0.333 0.667
E13.7 With multiple complications
0.000 0.333 0.667
E13.6 With other specified complications
0.000 0.333 0.667
E13.5 With peripheral circulatory complications
0.000 0.333 0.667
E13.4 With neurological complications
0.000 0.333 0.667
E13.3 With ophthalmic complications
0.000 0.333 0.667
E13.2 With renal complications
0.000 0.333 0.667
E13.1 With ketoacidosis
0.000 0.333 0.667
E13.0 With coma
0.000 0.333 0.667
E79 Disorders of purine and pyrimidine metabolism
0.000 0.334 0.666
E77 Disorders of glycoprotein metabolism
0.000 0.335 0.665
E76 Disorders of glycosaminoglycan metabolism
0.000 0.335 0.665
E72 Other disorders of amino-acid metabolism
0.000 0.335 0.665
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.335 0.665
E70 Disorders of aromatic amino-acid metabolism
0.000 0.335 0.665
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.335 0.665
I22.8 Subsequent myocardial infarction of other sites
0.000 0.338 0.662
E78.4 Other hyperlipidaemia
0.000 0.339 0.661
E85.9 Amyloidosis, unspecified
0.000 0.342 0.658
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.343 0.656
E16.2 Hypoglycaemia, unspecified
0.000 0.344 0.656
I12.9 Hypertensive renal disease without renal failure
0.000 0.354 0.646
L42 Pityriasis rosea
0.000 0.355 0.645
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.356 0.644
L44 Other papulosquamous disorders
0.000 0.363 0.637
L41 Parapsoriasis
0.000 0.363 0.637
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.363 0.637
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.365 0.635
I11 Hypertensive heart disease
0.000 0.367 0.633
E78.5 Hyperlipidaemia, unspecified
0.000 0.373 0.627
E11.4 With neurological complications
0.000 0.375 0.625
I20.1 Angina pectoris with documented spasm
0.000 0.378 0.622
L43.3 Subacute (active) lichen planus
0.000 0.381 0.619
L43.2 Lichenoid drug reaction
0.000 0.381 0.619
L43.1 Bullous lichen planus
0.000 0.381 0.619
L43.0 Hypertrophic lichen planus
0.000 0.381 0.619
I23.8 Other current complications following acute myocardial infarction
0.000 0.384 0.616
E84 Cystic fibrosis
0.000 0.390 0.609
I13 Hypertensive heart and renal disease
0.000 0.391 0.609
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.393 0.607
E00 Congenital iodine-deficiency syndrome
0.000 0.393 0.607
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.394 0.605
E40-E46 Malnutrition
0.000 0.405 0.595
E15 Nondiabetic hypoglycaemic coma
0.000 0.413 0.587
I25.4 Coronary artery aneurysm
0.000 0.416 0.583
E85.4 Organ-limited amyloidosis
0.000 0.419 0.581
E03.5 Myxoedema coma
0.000 0.419 0.581
E03.4 Atrophy of thyroid (acquired)
0.000 0.419 0.581
E03.3 Postinfectious hypothyroidism
0.000 0.419 0.581
E03.1 Congenital hypothyroidism without goitre
0.000 0.419 0.581
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.419 0.581
E16.1 Other hypoglycaemia
0.000 0.421 0.579
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.421 0.578
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.428 0.572
E05.5 Thyroid crisis or storm
0.000 0.433 0.567
E05.4 Thyrotoxicosis factitia
0.000 0.433 0.567
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.433 0.567
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.433 0.567
Chapter IX Diseases of the circulatory system
0.000 0.436 0.564
E07 Other disorders of thyroid
0.000 0.441 0.559
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.443 0.556
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.443 0.556
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.443 0.556
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.443 0.556
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.443 0.556
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.443 0.556
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.443 0.556
E11.3 With ophthalmic complications
0.000 0.443 0.557
E85.8 Other amyloidosis
0.000 0.444 0.556
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.444 0.556
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.444 0.556
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.444 0.556
E85.3 Secondary systemic amyloidosis
0.000 0.455 0.545
E73 Lactose intolerance
0.000 0.457 0.542
I15.8 Other secondary hypertension
0.000 0.463 0.536
I15.2 Hypertension secondary to endocrine disorders
0.000 0.463 0.536
I15.0 Renovascular hypertension
0.000 0.463 0.536
E89.3 Postprocedural hypopituitarism
0.000 0.468 0.532
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.473 0.527
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.473 0.527
E16.4 Abnormal secretion of gastrin
0.000 0.473 0.527
E16.3 Increased secretion of glucagon
0.000 0.473 0.527
I15.9 Seconday hypertension, unspecified
0.000 0.473 0.527
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.475 0.525
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.476 0.524
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.476 0.523
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.481 0.519
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.481 0.519
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.481 0.519
E74.2 Disorders of galactose metabolism
0.000 0.481 0.519
E74.1 Disorders of fructose metabolism
0.000 0.481 0.519
E74.0 Glycogen storage disease
0.000 0.481 0.519
E83 Disorders of mineral metabolism
0.391 0.485 0.125
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.486 0.514
I24.1 Dressler's syndrome
0.000 0.490 0.510
E11.8 With unspecified complications
0.000 0.497 0.502
G36.0 Neuromyelitis optica [Devic]
0.502 0.498 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.499 0.501
E06 Thyroiditis
0.000 0.499 0.501
G36.9 Acute disseminated demyelination, unspecified
0.499 0.501 0.000
G36.8 Other specified acute disseminated demyelination
0.499 0.501 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.499 0.501 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.521 0.479
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.522 0.478
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.522 0.478
E79.1 Lesch-Nyhan syndrome
0.000 0.522 0.478
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.523 0.477
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.523 0.477
E70.3 Albinism
0.000 0.523 0.477
E70.2 Disorders of tyrosine metabolism
0.000 0.523 0.477
E70.1 Other hyperphenylalaninaemias
0.000 0.523 0.477
E70.0 Classical phenylketonuria
0.000 0.523 0.477
E71.3 Disorders of fatty-acid metabolism
0.000 0.523 0.477
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.523 0.477
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.523 0.477
E71.0 Maple-syrup-urine disease
0.000 0.523 0.477
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.523 0.477
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.523 0.477
E72.5 Disorders of glycine metabolism
0.000 0.523 0.477
E72.4 Disorders of ornithine metabolism
0.000 0.523 0.477
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.523 0.477
E72.2 Disorders of urea cycle metabolism
0.000 0.523 0.477
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.523 0.477
E72.0 Disorders of amino-acid transport
0.000 0.523 0.477
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.523 0.477
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.523 0.477
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.523 0.477
E76.2 Other mucopolysaccharidoses
0.000 0.523 0.477
E76.1 Mucopolysaccharidosis, type II
0.000 0.523 0.477
E76.0 Mucopolysaccharidosis, type I
0.000 0.523 0.477
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.523 0.477
E77.8 Other disorders of glycoprotein metabolism
0.000 0.523 0.477
E77.1 Defects in glycoprotein degradation
0.000 0.523 0.477
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.523 0.477
E75.6 Lipid storage disorder, unspecified
0.000 0.529 0.471
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.529 0.471
E75.3 Sphingolipidosis, unspecified
0.000 0.529 0.471
E75.2 Other sphingolipidosis
0.000 0.529 0.471
E75.1 Other gangliosidosis
0.000 0.529 0.471
E75.0 GM2 gangliosidosis
0.000 0.529 0.471
I12.0 Hypertensive renal disease with renal failure
0.000 0.531 0.469
E05.8 Other thyrotoxicosis
0.000 0.534 0.465
E88 Other metabolic disorders
0.000 0.534 0.465
E75.5 Other lipid storage disorders
0.000 0.538 0.462
L41.9 Parapsoriasis, unspecified
0.000 0.543 0.457
L41.8 Other parapsoriasis
0.000 0.543 0.457
L41.5 Retiform parapsoriasis
0.000 0.543 0.457
L41.4 Large plaque parapsoriasis
0.000 0.543 0.457
L41.3 Small plaque parapsoriasis
0.000 0.543 0.457
L41.2 Lymphomatoid papulosis
0.000 0.543 0.457
L41.1 Pityriasis lichenoides chronica
0.000 0.543 0.457
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.543 0.457
L44.9 Papulosquamous disorder, unspecified
0.000 0.543 0.457
L44.8 Other specified papulosquamous disorders
0.000 0.543 0.457
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.543 0.457
L44.3 Lichen ruber moniliformis
0.000 0.543 0.457
L44.2 Lichen striatus
0.000 0.543 0.457
L44.1 Lichen nitidus
0.000 0.543 0.457
L44.0 Pityriasis rubra pilaris
0.000 0.543 0.457
E65-E68 Obesity and other hyperalimentation
0.000 0.549 0.451
E84.8 Cystic fibrosis with other manifestations
0.000 0.563 0.437
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.563 0.437
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.563 0.437
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.563 0.436
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.563 0.436
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.563 0.436
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.563 0.436
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.565 0.435
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.565 0.435
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.565 0.435
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.565 0.435
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.565 0.435
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.565 0.435
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.565 0.435
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.565 0.435
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.566 0.434
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.566 0.434
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.566 0.434
E89.5 Postprocedural testicular hypofunction
0.000 0.566 0.434
E89.1 Postprocedural hypoinsulinaemia
0.000 0.566 0.434
K90 Intestinal malabsorption
0.000 0.572 0.428
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.573 0.426
E45 Retarded development following protein-energy malnutrition
0.000 0.573 0.426
E43 Unspecified severe protein-energy malnutrition
0.000 0.573 0.426
E42 Marasmic kwashiorkor
0.000 0.573 0.426
E41 Nutritional marasmus
0.000 0.573 0.426
E40 Kwashiorkor
0.000 0.573 0.426
E50-E64 Other nutritional deficiencies
0.000 0.582 0.418
E89.4 Postprocedural ovarian failure
0.000 0.592 0.408
I00-I02 Acute rheumatic fever
0.000 0.595 0.404
E07.1 Dyshormogenetic goitre
0.000 0.599 0.401
E07.0 Hypersecretion of calcitonin
0.000 0.599 0.401
E07.8 Other specified disorders of thyroid
0.000 0.600 0.400
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.601 0.399
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.602 0.398
E73.8 Other lactose intolerance
0.000 0.611 0.389
E73.1 Secondary lactase deficiency
0.000 0.611 0.389
E73.0 Congenital lactase deficiency
0.000 0.611 0.389
E89.2 Postprocedural hypoparathyroidism
0.000 0.615 0.385
E84.9 Cystic fibrosis, unspecified
0.001 0.618 0.381
E80.6 Other disorders of bilirubin metabolism
0.000 0.623 0.377
E83.3 Disorders of phosphorus metabolism
0.337 0.624 0.039
E88.2 Lipomatosis, not elsewhere classified
0.000 0.629 0.370
E83.9 Disorder of mineral metabolism, unspecified
0.280 0.630 0.089
E83.8 Other disorders of mineral metabolism
0.280 0.630 0.089
E83.2 Disorders of zinc metabolism
0.280 0.630 0.089
E83.0 Disorders of copper metabolism
0.280 0.630 0.089
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.640 0.359
E80.5 Crigler-Najjar syndrome
0.000 0.640 0.359
E80.3 Defects of catalase and peroxydase
0.000 0.640 0.359
E80.2 Other porphyria
0.000 0.640 0.359
E80.1 Porphyria cutanea tarda
0.000 0.640 0.359
E80.0 Hereditary erythropoietic porphyria
0.000 0.640 0.359
E06.5 Other chronic thyroiditis
0.000 0.640 0.359
E06.4 Drug-induced thyroiditis
0.000 0.640 0.359
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.640 0.359
E06.1 Subacute thyroiditis
0.000 0.640 0.359
E06.0 Acute thyroiditis
0.000 0.640 0.359
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.646 0.354
E07.9 Disorder of thyroid, unspecified
0.000 0.646 0.354
E46 Unspecified protein-energy malnutrition
0.000 0.649 0.351
E03.8 Other specified hypothyroidism
0.001 0.654 0.345
E06.9 Thyroiditis, unspecified
0.000 0.658 0.342
E88.8 Other specified metabolic disorders
0.000 0.664 0.335
E88.9 Metabolic disorder, unspecified
0.000 0.666 0.334
E88.3 Tumour lysis syndrome
0.000 0.669 0.330
E67 Other hyperalimentation
0.000 0.676 0.324
E68 Sequelae of hyperalimentation
0.000 0.676 0.324
E65 Localised adiposity
0.000 0.684 0.316
E61 Deficiency of other nutrient elements
0.000 0.685 0.315
K90.9 Intestinal malabsorption, unspecified
0.000 0.689 0.311
K90.8 Other intestinal malabsorption
0.000 0.692 0.308
K90.3 Pancreatic steatorrhoea
0.000 0.693 0.307
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.693 0.307
K90.1 Tropical sprue
0.000 0.693 0.307
E44.1 Mild protein-energy malnutrition
0.000 0.694 0.306
E44.0 Moderate protein-energy malnutrition
0.000 0.694 0.306
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.700 0.300
E63 Other nutritional deficiencies
0.000 0.700 0.300
E56 Other vitamin deficiencies
0.000 0.700 0.300
E51 Thiamine deficiency
0.000 0.700 0.300
E50 Vitamin A deficiency
0.000 0.700 0.300
E60 Dietary zinc deficiency
0.000 0.700 0.300
E59 Dietary selenium deficiency
0.000 0.700 0.300
E58 Dietary calcium deficiency
0.000 0.700 0.300
E54 Ascorbic acid deficiency
0.000 0.700 0.300
E52 Niacin deficiency [pellagra]
0.000 0.700 0.300
I02 Rheumatic chorea
0.000 0.710 0.290
I01 Rheumatic fever with heart involvement
0.000 0.710 0.290
I00 Rheumatic fever without mention of heart involvement
0.000 0.710 0.290
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.715 0.285
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.718 0.282
E06.3 Autoimmune thyroiditis
0.000 0.719 0.281
E20-E35 Disorders of other endocrine glands
0.000 0.726 0.274
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.730 0.269
E73.9 Lactose intolerance, unspecified
0.001 0.733 0.266
E61.1 Iron deficiency
0.000 0.752 0.248
E89.0 Postprocedural hypothyroidism
0.000 0.757 0.243
E55 Vitamin D deficiency
0.000 0.760 0.240
E67.8 Other specified hyperalimentation
0.000 0.768 0.232
E67.3 Hypervitaminosis D
0.000 0.768 0.232
E67.2 Megavitamin-B6 syndrome
0.000 0.768 0.232
E67.1 Hypercarotenaemia
0.000 0.768 0.232
E67.0 Hypervitaminosis A
0.000 0.768 0.232
E23 Hypofunction and other disorders of pituitary gland
0.000 0.772 0.228
E61.9 Deficiency of nutrient element, unspecified
0.000 0.774 0.226
E61.8 Deficiency of other specified nutrient elements
0.000 0.774 0.226
E61.7 Deficiency of multiple nutrient elements
0.000 0.774 0.226
E61.6 Vanadium deficiency
0.000 0.774 0.226
E61.5 Molybdenum deficiency
0.000 0.774 0.226
E61.4 Chromium deficiency
0.000 0.774 0.226
E61.3 Manganese deficiency
0.000 0.774 0.226
E61.0 Copper deficiency
0.000 0.774 0.226
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.779 0.220
E22 Hyperfunction of pituitary gland
0.000 0.779 0.221
E61.2 Magnesium deficiency
0.000 0.783 0.217
E50.9 Vitamin A deficiency, unspecified
0.000 0.785 0.215
E50.8 Other manifestations of vitamin A deficiency
0.000 0.785 0.215
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.785 0.215
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.785 0.215
E50.5 Vitamin A deficiency with night blindness
0.000 0.785 0.215
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.785 0.215
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.785 0.215
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.785 0.215
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.785 0.215
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.785 0.215
E51.9 Thiamine deficiency, unspecified
0.000 0.785 0.215
E51.8 Other manifestations of thiamine deficiency
0.000 0.785 0.215
E51.2 Wernicke's encephalopathy
0.000 0.785 0.215
E51.1 Beriberi
0.000 0.785 0.215
E56.9 Vitamin deficiency, unspecified
0.000 0.785 0.215
E56.8 Deficiency of other vitamins
0.000 0.785 0.215
E56.1 Deficiency of vitamin K
0.000 0.785 0.215
E56.0 Deficiency of vitamin E
0.000 0.785 0.215
E63.9 Nutritional deficiency, unspecified
0.000 0.785 0.215
E63.8 Other specified nutritional deficiencies
0.000 0.785 0.215
E63.1 Imbalance of constituents of food intake
0.000 0.785 0.215
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.785 0.215
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.785 0.215
E64.8 Sequelae of other nutritional deficiencies
0.000 0.785 0.215
E64.3 Sequelae of rickets
0.000 0.785 0.215
E64.2 Sequelae of vitamin C deficiency
0.000 0.785 0.215
E64.1 Sequelae of vitamin A deficiency
0.000 0.785 0.215
E64.0 Sequelae of protein-energy malnutrition
0.000 0.785 0.215
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.792 0.208
I01.8 Other acute rheumatic heart disease
0.000 0.792 0.208
I01.2 Acute rheumatic myocarditis
0.000 0.792 0.208
I01.1 Acute rheumatic endocarditis
0.000 0.792 0.208
I01.0 Acute rheumatic pericarditis
0.000 0.792 0.208
I02.9 Rheumatic chorea without heart involvement
0.000 0.792 0.208
I02.0 Rheumatic chorea with heart involvement
0.000 0.792 0.208
E83.4 Disorders of magnesium metabolism
0.124 0.793 0.083
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.803 0.196
E32 Diseases of thymus
0.000 0.803 0.196
E31 Polyglandular dysfunction
0.000 0.803 0.196
E30 Disorders of puberty, not elsewhere classified
0.000 0.803 0.196
E25 Adrenogenital disorders
0.000 0.803 0.196
E26 Hyperaldosteronism
0.000 0.807 0.193
E23.6 Other disorders of pituitary gland
0.000 0.808 0.191
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.811 0.189
E23.2 Diabetes insipidus
0.000 0.813 0.187
E24 Cushing's syndrome
0.000 0.816 0.184
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.818 0.182
E29 Testicular dysfunction
0.000 0.819 0.181
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.823 0.177
E20 Hypoparathyroidism
0.000 0.823 0.176
E23.7 Disorder of pituitary gland, unspecified
0.000 0.827 0.173
E55.0 Rickets, active
0.000 0.828 0.172
E28 Ovarian dysfunction
0.000 0.833 0.167
E83.5 Disorders of calcium metabolism
0.140 0.836 0.024
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.836 0.163
E23.1 Drug-induced hypopituitarism
0.000 0.836 0.163
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.001 0.840 0.159
E22.1 Hyperprolactinaemia
0.000 0.841 0.159
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.842 0.158
E22.8 Other hyperfunction of pituitary gland
0.000 0.842 0.158
I28 Other diseases of pulmonary vessels
0.001 0.843 0.156
E80.4 Gilbert's syndrome
0.000 0.846 0.153
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.847 0.153
E22.0 Acromegaly and pituitary gigantism
0.000 0.856 0.144
E25.9 Adrenogenital disorder, unspecified
0.000 0.859 0.141
E25.8 Other adrenogenital disorders
0.000 0.859 0.141
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.859 0.141
E30.9 Disorder of puberty, unspecified
0.000 0.859 0.141
E30.8 Other disorders of puberty
0.000 0.859 0.141
E30.1 Precocious puberty
0.000 0.859 0.141
E30.0 Delayed puberty
0.000 0.859 0.141
E31.9 Polyglandular dysfunction, unspecified
0.000 0.859 0.141
E31.8 Other polyglandular dysfunction
0.000 0.859 0.141
E31.1 Polyglandular hyperfunction
0.000 0.859 0.141
E31.0 Autoimmune polyglandular failure
0.000 0.859 0.141
E32.9 Disease of thymus, unspecified
0.000 0.859 0.141
E32.8 Other diseases of thymus
0.000 0.859 0.141
E32.1 Abscess of thymus
0.000 0.859 0.141
E32.0 Persistent hyperplasia of thymus
0.000 0.859 0.141
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.859 0.141
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.859 0.141
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.859 0.141
E21.3 Hyperparathyroidism, unspecified
0.000 0.859 0.141
E34 Other endocrine disorders
0.000 0.860 0.140
E26.9 Hyperaldosteronism, unspecified
0.000 0.861 0.138
E26.8 Other hyperaldosteronism
0.000 0.861 0.138
E26.1 Secondary hyperaldosteronism
0.000 0.861 0.138
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.862 0.138
M75.0 Adhesive capsulitis of shoulder
0.000 0.864 0.136
E53 Deficiency of other B group vitamins
0.001 0.865 0.135
E26.0 Primary hyperaldosteronism
0.000 0.865 0.135
E24.8 Other Cushing's syndrome
0.000 0.868 0.132
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.868 0.132
E24.3 Ectopic ACTH syndrome
0.000 0.868 0.132
E24.2 Drug-induced Cushing's syndrome
0.000 0.868 0.132
E24.1 Nelson's syndrome
0.000 0.868 0.132
E24.0 Pituitary-dependent Cushing's disease
0.000 0.868 0.132
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.870 0.130
E21.4 Other specified disorders of parathyroid gland
0.000 0.870 0.130
E21.2 Other hyperparathyroidism
0.000 0.870 0.130
E29.9 Testicular dysfunction, unspecified
0.000 0.870 0.130
E29.8 Other testicular dysfunction
0.000 0.870 0.130

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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