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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130941
log Bayes Factor = 54.7752
Chromosome 6   position 31,197,514  (GRCh37) Explore rs3130941 on Ensembl!
Variant rs3130941 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
E11.9 Without complications
0.000 0.001 0.999
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.002 0.998
I25.1 Atherosclerotic heart disease
0.000 0.002 0.998
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.005 0.995
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.005 0.995
J45.9 Asthma, unspecified
0.000 0.008 0.992
K51.9 Ulcerative colitis, unspecified
0.988 0.012 0.000
K51 Ulcerative colitis
0.986 0.014 0.000
L40-L45 Papulosquamous disorders
0.000 0.016 0.984
I21 Acute myocardial infarction
0.000 0.018 0.982
E10.3 With ophthalmic complications
0.000 0.022 0.978
E14 Unspecified diabetes mellitus
0.000 0.023 0.977
I10 Essential (primary) hypertension
0.000 0.024 0.976
I25.5 Ischaemic cardiomyopathy
0.000 0.025 0.975
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.026 0.974
L43 Lichen planus
0.000 0.027 0.973
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.029 0.971
I10-I15 Hypertensive diseases
0.000 0.031 0.969
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.034 0.966
E70-E90 Metabolic disorders
0.000 0.035 0.965
L43.9 Lichen planus, unspecified
0.000 0.036 0.964
E14.9 Without complications
0.000 0.041 0.959
I21.9 Acute myocardial infarction, unspecified
0.000 0.050 0.950
I22 Subsequent myocardial infarction
0.000 0.053 0.947
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.054 0.946
Chapter IX Diseases of the circulatory system
0.000 0.060 0.940
K51.3 Ulcerative (chronic) rectosigmoiditis
0.930 0.070 0.000
I21.4 Acute subendocardial myocardial infarction
0.000 0.071 0.929
G35-G37 Demyelinating diseases of the central nervous system
0.925 0.075 0.000
K51.8 Other ulcerative colitis
0.920 0.080 0.000
I24 Other acute ischaemic heart diseases
0.000 0.083 0.917
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.085 0.915
E78.8 Other disorders of lipoprotein metabolism
0.000 0.092 0.908
G37 Other demyelinating diseases of central nervous system
0.906 0.094 0.000
E11.0 With coma
0.000 0.099 0.901
I12 Hypertensive renal disease
0.000 0.102 0.898
E78.2 Mixed hyperlipidaemia
0.000 0.104 0.896
I20 Angina pectoris
0.000 0.113 0.887
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.113 0.886
E10.1 With ketoacidosis
0.000 0.117 0.883
M06 Other rheumatoid arthritis
0.000 0.118 0.882
K51.4 Pseudopolyposis of colon
0.880 0.120 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.880 0.120 0.000
K51.2 Ulcerative (chronic) proctitis
0.876 0.124 0.000
K51.5 Mucosal proctocolitis
0.869 0.131 0.000
L40.0 Psoriasis vulgaris
0.000 0.135 0.865
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.137 0.863
E10.4 With neurological complications
0.000 0.141 0.859
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.142 0.858
I12.9 Hypertensive renal disease without renal failure
0.000 0.149 0.851
I20.9 Angina pectoris, unspecified
0.000 0.150 0.850
K90 Intestinal malabsorption
0.000 0.152 0.848
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.153 0.847
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.159 0.841
L40.8 Other psoriasis
0.000 0.167 0.833
I23 Certain current complications following acute myocardial infarction
0.000 0.172 0.828
E16 Other disorders of pancreatic internal secretion
0.000 0.174 0.826
E13 Other specified diabetes mellitus
0.000 0.176 0.824
E11.1 With ketoacidosis
0.000 0.181 0.819
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.183 0.816
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.184 0.816
E10.0 With coma
0.000 0.193 0.807
E11.5 With peripheral circulatory complications
0.000 0.196 0.804
E10.8 With unspecified complications
0.000 0.202 0.798
E78.5 Hyperlipidaemia, unspecified
0.000 0.208 0.792
E74 Other disorders of carbohydrate metabolism
0.000 0.214 0.785
I15 Secondary hypertension
0.000 0.216 0.784
E11.2 With renal complications
0.000 0.219 0.781
E16.2 Hypoglycaemia, unspecified
0.000 0.222 0.778
E11.6 With other specified complications
0.000 0.226 0.774
E10.6 With other specified complications
0.000 0.226 0.774
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.229 0.771
E10.5 With peripheral circulatory complications
0.000 0.230 0.770
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.230 0.770
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.233 0.767
E14.3 With ophthalmic complications
0.000 0.233 0.767
I25.3 Aneurysm of heart
0.000 0.241 0.759
M05-M14 Inflammatory polyarthropathies
0.000 0.241 0.759
M45 Ankylosing spondylitis
0.000 0.243 0.757
K51.1 Ulcerative (chronic) ileocolitis
0.751 0.249 0.000
E78.4 Other hyperlipidaemia
0.000 0.254 0.746
K51.0 Ulcerative (chronic) enterocolitis
0.745 0.255 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.737 0.263 0.000
L43.8 Other lichen planus
0.000 0.264 0.736
E10.2 With renal complications
0.000 0.265 0.735
E78.1 Pure hyperglyceridaemia
0.000 0.268 0.731
L42 Pityriasis rosea
0.000 0.276 0.724
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.287 0.713
E78.3 Hyperchylomicronaemia
0.000 0.287 0.713
I22.8 Subsequent myocardial infarction of other sites
0.000 0.288 0.712
M07 Psoriatic and enteropathic arthropathies
0.000 0.292 0.708
L44 Other papulosquamous disorders
0.000 0.294 0.706
L41 Parapsoriasis
0.000 0.294 0.706
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.294 0.706
I11 Hypertensive heart disease
0.000 0.295 0.705
I23.8 Other current complications following acute myocardial infarction
0.000 0.295 0.705
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.296 0.704
M45-M49 Spondylopathies
0.000 0.298 0.702
E14.8 With unspecified complications
0.000 0.299 0.701
E14.7 With multiple complications
0.000 0.299 0.701
E14.6 With other specified complications
0.000 0.299 0.701
E14.5 With peripheral circulatory complications
0.000 0.299 0.701
E14.2 Withrenal complications
0.000 0.299 0.701
E14.1 With ketoacidosis
0.000 0.299 0.701
E14.0 With coma
0.000 0.299 0.701
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.300 0.700
M06.3 Rheumatoid nodule
0.000 0.300 0.700
I24.8 Other forms of acute ischaemic heart disease
0.000 0.301 0.699
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.699 0.301 0.000
E13.9 Without complications
0.000 0.302 0.698
L43.3 Subacute (active) lichen planus
0.000 0.302 0.698
L43.2 Lichenoid drug reaction
0.000 0.302 0.698
L43.1 Bullous lichen planus
0.000 0.302 0.698
L43.0 Hypertrophic lichen planus
0.000 0.302 0.698
M06.4 Inflammatory polyarthropathy
0.000 0.303 0.697
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.303 0.697
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.303 0.697
# Top node
0.000 0.304 0.696
I13 Hypertensive heart and renal disease
0.000 0.305 0.695
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.305 0.695
I20.0 Unstable angina
0.000 0.307 0.693
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.308 0.692
E79 Disorders of purine and pyrimidine metabolism
0.000 0.308 0.692
E77 Disorders of glycoprotein metabolism
0.000 0.308 0.692
E76 Disorders of glycosaminoglycan metabolism
0.000 0.308 0.692
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.308 0.692
E72 Other disorders of amino-acid metabolism
0.000 0.308 0.692
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.308 0.692
E70 Disorders of aromatic amino-acid metabolism
0.000 0.308 0.692
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.308 0.692
G36 Other acute disseminated demyelination
0.685 0.314 0.000
E83 Disorders of mineral metabolism
0.440 0.317 0.243
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.320 0.680
E11.4 With neurological complications
0.000 0.321 0.679
K90-K93 Other diseases of the digestive system
0.000 0.322 0.678
M07.3 Other psoriatic arthropathies
0.000 0.322 0.678
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.328 0.672
E84 Cystic fibrosis
0.000 0.329 0.670
Chapter XI Diseases of the digestive system
0.000 0.338 0.662
K55-K64 Other diseases of intestines
0.000 0.339 0.661
K58 Irritable bowel syndrome
0.000 0.340 0.660
K57 Diverticular disease of intestine
0.000 0.341 0.659
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.343 0.657
E14.4 With neurological complications
0.000 0.346 0.654
K57.3 Diverticular disease of large intestine without perforation or abscess
0.000 0.347 0.653
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.349 0.651
E40-E46 Malnutrition
0.000 0.349 0.650
K90.9 Intestinal malabsorption, unspecified
0.000 0.350 0.650
G37.5 Concentric sclerosis [Balo]
0.649 0.351 0.000
G37.4 Subacute necrotising myelitis
0.649 0.351 0.000
G37.2 Central pontine myelinolysis
0.649 0.351 0.000
G37.1 Central demyelination of corpus callosum
0.649 0.351 0.000
G37.0 Diffuse sclerosis
0.649 0.351 0.000
K60 Fissure and fistula of anal and rectal regions
0.000 0.358 0.642
E85 Amyloidosis
0.000 0.361 0.638
K90.8 Other intestinal malabsorption
0.000 0.362 0.638
L40.3 Pustulosis palmaris et plantaris
0.000 0.364 0.636
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.364 0.636
E15 Nondiabetic hypoglycaemic coma
0.000 0.364 0.636
I15.9 Seconday hypertension, unspecified
0.000 0.365 0.635
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.366 0.634
K60.2 Anal fissure, unspecified
0.000 0.367 0.633
M06.8 Other specified rheumatoid arthritis
0.000 0.368 0.632
M06.2 Rheumatoid bursitis
0.000 0.368 0.632
M06.1 Adult-onset Still's disease
0.000 0.368 0.632
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.377 0.623
E20-E35 Disorders of other endocrine glands
0.000 0.378 0.622
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.379 0.621
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.379 0.621
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.380 0.620
I24.1 Dressler's syndrome
0.000 0.382 0.618
I00-I02 Acute rheumatic fever
0.000 0.382 0.618
I12.0 Hypertensive renal disease with renal failure
0.000 0.383 0.617
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.386 0.613
K90.3 Pancreatic steatorrhoea
0.000 0.392 0.608
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.392 0.608
K90.1 Tropical sprue
0.000 0.392 0.608
Chapter VIII Diseases of the ear and mastoid process
0.000 0.394 0.606
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.000 0.403 0.597
I25.4 Coronary artery aneurysm
0.000 0.404 0.596
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.406 0.594
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.406 0.594
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.406 0.594
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.406 0.594
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.406 0.594
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.406 0.594
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.406 0.594
K60.0 Acute anal fissure
0.000 0.407 0.593
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.407 0.592
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.407 0.592
E16.4 Abnormal secretion of gastrin
0.000 0.407 0.592
E16.3 Increased secretion of glucagon
0.000 0.407 0.592
E16.1 Other hypoglycaemia
0.000 0.407 0.592
E13.8 With unspecified complications
0.000 0.409 0.591
E13.7 With multiple complications
0.000 0.409 0.591
E13.6 With other specified complications
0.000 0.409 0.591
E13.5 With peripheral circulatory complications
0.000 0.409 0.591
E13.4 With neurological complications
0.000 0.409 0.591
E13.3 With ophthalmic complications
0.000 0.409 0.591
E13.2 With renal complications
0.000 0.409 0.591
E13.1 With ketoacidosis
0.000 0.409 0.591
E13.0 With coma
0.000 0.409 0.591
I15.1 Hypertension secondary to other renal disorders
0.000 0.412 0.588
H60-H62 Diseases of external ear
0.000 0.413 0.587
I20.1 Angina pectoris with documented spasm
0.000 0.415 0.585
K57.1 Diverticular disease of small intestine without perforation or abscess
0.000 0.419 0.581
H60 Otitis externa
0.000 0.426 0.574
E11.8 With unspecified complications
0.000 0.429 0.571
M49 Spondylopathies in diseases classified elsewhere
0.000 0.430 0.570
M06.34 Rheumatoid nodule (Hand)
0.000 0.431 0.569
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.433 0.567
M05 Seropositive rheumatoid arthritis
0.000 0.434 0.566
M06.0 Seronegative rheumatoid arthritis
0.000 0.435 0.565
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.436 0.564
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.437 0.563
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.437 0.563
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.437 0.563
E74.2 Disorders of galactose metabolism
0.000 0.437 0.563
E74.1 Disorders of fructose metabolism
0.000 0.437 0.563
E74.0 Glycogen storage disease
0.000 0.437 0.563
I15.8 Other secondary hypertension
0.000 0.437 0.562
I15.2 Hypertension secondary to endocrine disorders
0.000 0.437 0.562
I15.0 Renovascular hypertension
0.000 0.437 0.562
M70-M79 Other soft tissue disorders
0.000 0.440 0.560
E28 Ovarian dysfunction
0.000 0.441 0.559
E11.3 With ophthalmic complications
0.000 0.444 0.556
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.449 0.551
I30-I52 Other forms of heart disease
0.000 0.455 0.545
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.456 0.544
M08 Juvenile arthritis
0.000 0.456 0.544
H60.9 Otitis externa, unspecified
0.000 0.457 0.543
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.457 0.543
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.457 0.543
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.457 0.543
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.457 0.543
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.457 0.543
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.457 0.543
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.457 0.543
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.457 0.543
M11 Other crystal arthropathies
0.000 0.463 0.537
E88 Other metabolic disorders
0.000 0.463 0.536
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.537 0.463 0.000
K70-K77 Diseases of liver
0.000 0.463 0.537
E73 Lactose intolerance
0.001 0.464 0.535
E89.3 Postprocedural hypopituitarism
0.000 0.466 0.534
E28.2 Polycystic ovarian syndrome
0.000 0.470 0.530
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.471 0.529
I46 Cardiac arrest
0.000 0.473 0.527
E50-E64 Other nutritional deficiencies
0.000 0.479 0.521
I46.9 Cardiac arrest, unspecified
0.000 0.479 0.521
I51 Complications and ill-defined descriptions of heart disease
0.000 0.482 0.518
I51.8 Other ill-defined heart diseases
0.000 0.485 0.515
H65-H75 Diseases of middle ear and mastoid
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
G36.0 Neuromyelitis optica [Devic]
0.514 0.486 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.488 0.512
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.489 0.511
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.490 0.510
M14 Arthropathies in other diseases classified elsewhere
0.000 0.490 0.509
M07.5 Arthropathy in ulcerative colitis
0.000 0.492 0.508
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.492 0.508
M07.2 Psoriatic spondylitis
0.000 0.492 0.508
M07.1 Arthritis mutilans
0.000 0.492 0.508
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.492 0.508
L41.9 Parapsoriasis, unspecified
0.000 0.494 0.506
L41.8 Other parapsoriasis
0.000 0.494 0.506
L41.5 Retiform parapsoriasis
0.000 0.494 0.506
L41.4 Large plaque parapsoriasis
0.000 0.494 0.506
L41.3 Small plaque parapsoriasis
0.000 0.494 0.506
L41.2 Lymphomatoid papulosis
0.000 0.494 0.506
L41.1 Pityriasis lichenoides chronica
0.000 0.494 0.506
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.494 0.506
L44.9 Papulosquamous disorder, unspecified
0.000 0.494 0.506
L44.8 Other specified papulosquamous disorders
0.000 0.494 0.506
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.494 0.506
L44.3 Lichen ruber moniliformis
0.000 0.494 0.506
L44.2 Lichen striatus
0.000 0.494 0.506
L44.1 Lichen nitidus
0.000 0.494 0.506
L44.0 Pityriasis rubra pilaris
0.000 0.494 0.506
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.497 0.503
M75 Shoulder lesions
0.000 0.497 0.503
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.498 0.502
M06.38 Rheumatoid nodule (Other)
0.000 0.498 0.502
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.498 0.502
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.498 0.502
M06.33 Rheumatoid nodule (Forearm)
0.000 0.498 0.502
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.498 0.502
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.498 0.502
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.498 0.502
E24 Cushing's syndrome
0.000 0.499 0.501
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.500 0.500
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.500 0.500
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.500 0.500
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.500 0.500
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.500 0.500
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.500 0.500
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.500 0.500
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.500 0.500
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.501 0.499
M75.0 Adhesive capsulitis of shoulder
0.000 0.501 0.499
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.502 0.498
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.502 0.498
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.502 0.498
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.502 0.498
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.503 0.497
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.504 0.496
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.504 0.496
E70.3 Albinism
0.000 0.504 0.496
E70.2 Disorders of tyrosine metabolism
0.000 0.504 0.496
E70.1 Other hyperphenylalaninaemias
0.000 0.504 0.496
E70.0 Classical phenylketonuria
0.000 0.504 0.496
E71.3 Disorders of fatty-acid metabolism
0.000 0.504 0.496
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.504 0.496
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.504 0.496
E71.0 Maple-syrup-urine disease
0.000 0.504 0.496
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.504 0.496
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.504 0.496
E72.5 Disorders of glycine metabolism
0.000 0.504 0.496
E72.4 Disorders of ornithine metabolism
0.000 0.504 0.496
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.504 0.496
E72.2 Disorders of urea cycle metabolism
0.000 0.504 0.496
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.504 0.496
E72.0 Disorders of amino-acid transport
0.000 0.504 0.496
E75.6 Lipid storage disorder, unspecified
0.000 0.504 0.496
E75.5 Other lipid storage disorders
0.000 0.504 0.496
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.504 0.496
E75.3 Sphingolipidosis, unspecified
0.000 0.504 0.496
E75.2 Other sphingolipidosis
0.000 0.504 0.496
E75.1 Other gangliosidosis
0.000 0.504 0.496
E75.0 GM2 gangliosidosis
0.000 0.504 0.496
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.504 0.496
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.504 0.496
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.504 0.496
E76.2 Other mucopolysaccharidoses
0.000 0.504 0.496
E76.1 Mucopolysaccharidosis, type II
0.000 0.504 0.496
E76.0 Mucopolysaccharidosis, type I
0.000 0.504 0.496
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.504 0.496
E77.8 Other disorders of glycoprotein metabolism
0.000 0.504 0.496
E77.1 Defects in glycoprotein degradation
0.000 0.504 0.496
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.504 0.496
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.504 0.496
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.504 0.496
E79.1 Lesch-Nyhan syndrome
0.000 0.504 0.496
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.504 0.496
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.000 0.504 0.496
E23 Hypofunction and other disorders of pituitary gland
0.000 0.506 0.494
G36.9 Acute disseminated demyelination, unspecified
0.491 0.508 0.000
G36.8 Other specified acute disseminated demyelination
0.491 0.508 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.491 0.508 0.000
H60.3 Other infective otitis externa
0.000 0.509 0.491
E83.9 Disorder of mineral metabolism, unspecified
0.316 0.510 0.174
E83.8 Other disorders of mineral metabolism
0.316 0.510 0.174
E83.2 Disorders of zinc metabolism
0.316 0.510 0.174
E83.0 Disorders of copper metabolism
0.316 0.510 0.174
K74 Fibrosis and cirrhosis of liver
0.000 0.511 0.489
I47 Paroxysmal tachycardia
0.000 0.511 0.489
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.514 0.486
M07.38 Other psoriatic arthropathies (Other)
0.000 0.514 0.486
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.514 0.486
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.514 0.486
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.514 0.486
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.514 0.486
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.514 0.486
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.514 0.486
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.517 0.483
M12 Other specific arthropathies
0.000 0.519 0.481
E84.8 Cystic fibrosis with other manifestations
0.000 0.519 0.481
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.519 0.481
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.519 0.481
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.520 0.480
I83 Varicose veins of lower extremities
0.470 0.521 0.008
M46 Other inflammatory spondylopathies
0.000 0.522 0.478
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.523 0.477
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.524 0.476
H71 Cholesteatoma of middle ear
0.000 0.525 0.475
I44 Atrioventricular and left bundle-branch block
0.000 0.526 0.474
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.526 0.474
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.000 0.527 0.473
M91-M94 Chondropathies
0.000 0.528 0.472
K72 Hepatic failure, not elsewhere classified
0.000 0.528 0.472
E85.9 Amyloidosis, unspecified
0.000 0.529 0.470
K60.5 Anorectal fistula
0.000 0.531 0.469
M07.6 Other enteropathic arthropathies
0.000 0.532 0.467
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.533 0.466
E45 Retarded development following protein-energy malnutrition
0.000 0.533 0.466
E43 Unspecified severe protein-energy malnutrition
0.000 0.533 0.466
E42 Marasmic kwashiorkor
0.000 0.533 0.466
E41 Nutritional marasmus
0.000 0.533 0.466
E40 Kwashiorkor
0.000 0.533 0.466
H74 Other disorders of middle ear and mastoid
0.000 0.535 0.465
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.536 0.464
K74.3 Primary biliary cirrhosis
0.000 0.536 0.464
M79.6 Pain in limb
0.000 0.536 0.464
E84.9 Cystic fibrosis, unspecified
0.000 0.540 0.459
E26 Hyperaldosteronism
0.000 0.541 0.459
H60.1 Cellulitis of external ear
0.000 0.542 0.458
E85.8 Other amyloidosis
0.000 0.542 0.458
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.542 0.458
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.542 0.458
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.542 0.458
E83.3 Disorders of phosphorus metabolism
0.369 0.543 0.088
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.000 0.543 0.457
K57.0 Diverticular disease of small intestine with perforation and abscess
0.000 0.544 0.455
H60.8 Other otitis externa
0.000 0.545 0.455
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.547 0.453
M06.18 Adult-onset Still's disease (Other)
0.000 0.547 0.453
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.547 0.453
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.547 0.453
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.547 0.453
M06.14 Adult-onset Still's disease (Hand)
0.000 0.547 0.453
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.547 0.453
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.547 0.453
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.547 0.453
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.547 0.453
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.547 0.453
M06.28 Rheumatoid bursitis (Other)
0.000 0.547 0.453
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.547 0.453
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.547 0.453
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.547 0.453
M06.24 Rheumatoid bursitis (Hand)
0.000 0.547 0.453
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.547 0.453
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.547 0.453
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.547 0.453
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.547 0.453
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.547 0.453
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.547 0.453
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.547 0.453
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.547 0.453
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.547 0.453
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.547 0.453
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.547 0.453
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.547 0.453
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.547 0.453
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.547 0.453
I44.7 Left bundle-branch block, unspecified
0.000 0.548 0.452
I83.0 Varicose veins of lower extremities with ulcer
0.448 0.550 0.002
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.551 0.449
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.554 0.446
E32 Diseases of thymus
0.000 0.554 0.446
E31 Polyglandular dysfunction
0.000 0.554 0.446
E30 Disorders of puberty, not elsewhere classified
0.000 0.554 0.446
E25 Adrenogenital disorders
0.000 0.554 0.446
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.556 0.444
E89.2 Postprocedural hypoparathyroidism
0.000 0.556 0.444
I02 Rheumatic chorea
0.000 0.557 0.443
I01 Rheumatic fever with heart involvement
0.000 0.557 0.443
I51.0 Cardiac septal defect, acquired
0.000 0.557 0.443
H61 Other disorders of external ear
0.000 0.558 0.442
K75 Other inflammatory liver diseases
0.000 0.558 0.442
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.560 0.440
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.560 0.440
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.560 0.440
E89.5 Postprocedural testicular hypofunction
0.000 0.560 0.440
E89.1 Postprocedural hypoinsulinaemia
0.000 0.560 0.440
M79.65 Pain in limb (Pelvic region and thigh)
0.000 0.563 0.437
E29 Testicular dysfunction
0.000 0.564 0.436
M79.7 Fibromyalgia
0.000 0.565 0.435
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.567 0.433
M65-M68 Disorders of synovium and tendon
0.000 0.569 0.431
E85.4 Organ-limited amyloidosis
0.000 0.569 0.430
E89.4 Postprocedural ovarian failure
0.000 0.571 0.429
E22 Hyperfunction of pituitary gland
0.000 0.573 0.427
K73 Chronic hepatitis, not elsewhere classified
0.000 0.573 0.427
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.574 0.426
L10-L14 Bullous disorders
0.000 0.578 0.421
E46 Unspecified protein-energy malnutrition
0.000 0.579 0.421
H60.4 Cholesteatoma of external ear
0.000 0.579 0.421
M79.1 Myalgia
0.000 0.580 0.420
M70.4 Prepatellar bursitis
0.000 0.580 0.420

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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