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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34159951
log Bayes Factor = 19.1998
Chromosome 5   position 45,689,447  (GRCh37) Explore rs34159951 on Ensembl!
Variant rs34159951 is part of Cluster X0020

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
I51 Complications and ill-defined descriptions of heart disease
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.996 0.004 0.000
M06.9 Rheumatoid arthritis, unspecified
0.994 0.006 0.000
I20-I25 Ischaemic heart diseases
0.993 0.007 0.000
Chapter II Neoplasms
0.993 0.007 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.990 0.010 0.000
M20-M25 Other joint disorders
0.986 0.014 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.986 0.014 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.983 0.017 0.000
E14 Unspecified diabetes mellitus
0.983 0.017 0.000
I51.7 Cardiomegaly
0.980 0.020 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.973 0.027 0.000
M07 Psoriatic and enteropathic arthropathies
0.972 0.028 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.970 0.030 0.000
Chapter VI Diseases of the nervous system
0.970 0.030 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.969 0.031 0.000
E10 Insulin-dependent diabetes mellitus
0.967 0.033 0.000
E70-E90 Metabolic disorders
0.966 0.034 0.000
I20 Angina pectoris
0.966 0.034 0.000
Chapter I Certain infectious and parasitic diseases
0.965 0.035 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.962 0.038 0.000
M31 Other necrotising vasculopathies
0.961 0.039 0.000
E14.9 Without complications
0.960 0.040 0.000
I20.9 Angina pectoris, unspecified
0.959 0.041 0.000
I05-I09 Chronic rheumatic heart diseases
0.957 0.043 0.000
L40-L45 Papulosquamous disorders
0.954 0.046 0.000
M07.3 Other psoriatic arthropathies
0.952 0.048 0.000
A00-A09 Intestinal infectious diseases
0.951 0.049 0.000
Chapter VIII Diseases of the ear and mastoid process
0.951 0.049 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.950 0.050 0.000
M45-M49 Spondylopathies
0.950 0.050 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.949 0.051 0.000
Chapter VII Diseases of the eye and adnexa
0.949 0.051 0.000
Chapter XX External causes of morbidity and mortality
0.946 0.054 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.944 0.056 0.000
L40 Psoriasis
0.943 0.057 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.941 0.059 0.000
M35 Other systemic involvement of connective tissue
0.941 0.059 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.938 0.062 0.000
I49 Other cardiac arrhythmias
0.936 0.064 0.000
I51.8 Other ill-defined heart diseases
0.935 0.065 0.000
H30-H36 Disorders of choroid and retina
0.934 0.066 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.934 0.066 0.000
R05 Cough
0.933 0.067 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.933 0.067 0.000
I21 Acute myocardial infarction
0.932 0.068 0.000
D70 Agranulocytosis
0.930 0.070 0.000
L40.5 Arthropathic psoriasis
0.929 0.071 0.000
M34 Systemic sclerosis
0.928 0.072 0.000
I44 Atrioventricular and left bundle-branch block
0.926 0.074 0.000
H33 Retinal detachments and breaks
0.924 0.076 0.000
I45 Other conduction disorders
0.924 0.076 0.000
I74 Arterial embolism and thrombosis
0.924 0.076 0.000
E20-E35 Disorders of other endocrine glands
0.923 0.077 0.000
M31.6 Other giant cell arteritis
0.922 0.078 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.921 0.079 0.000
H33.2 Serous retinal detachment
0.920 0.080 0.000
E10.9 Without complications
0.918 0.082 0.000
C34 Malignant neoplasm of bronchus and lung
0.918 0.082 0.000
E11 Non-insulin-dependent diabetes mellitus
0.918 0.082 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.917 0.083 0.000
C64-C68 Malignant neoplasms of urinary tract
0.914 0.086 0.000
I08 Multiple valve diseases
0.913 0.087 0.000
S90-S99 Injuries to the ankle and foot
0.912 0.088 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.905 0.095 0.000
S80-S89 Injuries to the knee and lower leg
0.904 0.096 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.901 0.099 0.000
Chapter X Diseases of the respiratory system
0.900 0.100 0.000
I51.9 Heart disease, unspecified
0.898 0.102 0.000
E86 Volume depletion
0.898 0.102 0.000
J44 Other chronic obstructive pulmonary disease
0.898 0.102 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.897 0.103 0.000
I44.0 Atrioventricular block, first degree
0.895 0.105 0.000
M47 Spondylosis
0.894 0.106 0.000
C79 Secondary malignant neoplasm of other sites
0.890 0.110 0.000
I50 Heart failure
0.887 0.113 0.000
J40-J47 Chronic lower respiratory diseases
0.886 0.114 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.880 0.120 0.000
I49.9 Cardiac arrhythmia, unspecified
0.878 0.122 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.877 0.123 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.874 0.126 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.867 0.133 0.000
Y43 Primarily systemic agents
0.867 0.133 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.866 0.133 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.866 0.134 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.862 0.138 0.000
I49.1 Atrial premature depolarisation
0.861 0.139 0.000
J09-J18 Influenza and pneumonia
0.861 0.139 0.000
H65-H75 Diseases of middle ear and mastoid
0.859 0.141 0.000
M35.0 Sicca syndrome [Sjogren]
0.856 0.144 0.000
E87.2 Acidosis
0.855 0.145 0.000
M24 Other specific joint derangements
0.854 0.146 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.854 0.146 0.000
M60-M63 Disorders of muscles
0.852 0.148 0.000
T66-T78 Other and unspecified effects of external causes
0.851 0.149 0.000
M13 Other arthritis
0.850 0.150 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.849 0.151 0.000
Q80-Q89 Other congenital malformations
0.849 0.151 0.000
C92 Myeloid leukaemia
0.846 0.154 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.846 0.154 0.000
E13 Other specified diabetes mellitus
0.845 0.155 0.000
M35.3 Polymyalgia rheumatica
0.844 0.156 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.844 0.156 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.844 0.156 0.000
I21.4 Acute subendocardial myocardial infarction
0.843 0.157 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.843 0.157 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.842 0.158 0.000
I51.4 Myocarditis, unspecified
0.842 0.158 0.000
E14.3 With ophthalmic complications
0.841 0.159 0.000
C34.9 Bronchus or lung, unspecified
0.840 0.160 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.840 0.160 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.839 0.161 0.000
E50-E64 Other nutritional deficiencies
0.838 0.162 0.000
M47.8 Other spondylosis
0.837 0.163 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.837 0.163 0.000
R06 Abnormalities of breathing
0.836 0.164 0.000
I77 Other disorders of arteries and arterioles
0.834 0.166 0.000
E85 Amyloidosis
0.832 0.167 0.000
I45.5 Other specified heart block
0.832 0.168 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.832 0.168 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.830 0.170 0.000
A30-A49 Other bacterial diseases
0.830 0.170 0.000
D00-D09 In situ neoplasms
0.829 0.171 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.827 0.173 0.000
I20.1 Angina pectoris with documented spasm
0.825 0.175 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.823 0.177 0.000
I08.0 Disorders of both mitral and aortic valves
0.822 0.178 0.000
M34.9 Systemic sclerosis, unspecified
0.822 0.178 0.000
I50.0 Congestive heart failure
0.818 0.182 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.817 0.183 0.000
R21 Rash and other nonspecific skin eruption
0.816 0.184 0.000
J18 Pneumonia, organism unspecified
0.816 0.184 0.000
H90-H95 Other disorders of ear
0.815 0.185 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.815 0.185 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.814 0.185 0.000
I05 Rheumatic mitral valve diseases
0.814 0.186 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.812 0.188 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.811 0.189 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.811 0.189 0.000
E23 Hypofunction and other disorders of pituitary gland
0.810 0.190 0.000
C51-C58 Malignant neoplasms of female genital organs
0.809 0.191 0.000
S81 Open wound of lower leg
0.808 0.192 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.808 0.192 0.000
G20-G26 Extrapyramidal and movement disorders
0.807 0.193 0.000
C34.0 Main bronchus
0.805 0.195 0.000
Q50-Q56 Congenital malformations of genital organs
0.804 0.196 0.000
H80-H83 Diseases of inner ear
0.804 0.196 0.000
I25 Chronic ischaemic heart disease
0.803 0.197 0.000
M80-M85 Disorders of bone density and structure
0.801 0.199 0.000
M34.1 CR(E)ST syndrome
0.799 0.201 0.000
L90 Atrophic disorders of skin
0.799 0.201 0.000
I44.7 Left bundle-branch block, unspecified
0.798 0.202 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.797 0.203 0.000
H36 Retinal disorders in diseases classified elsewhere
0.795 0.204 0.000
D50-D53 Nutritional anaemias
0.795 0.205 0.000
E87.7 Fluid overload
0.793 0.207 0.000
Y52 Agents primarily affecting the cardiovascular system
0.793 0.207 0.000
C81 Hodgkin's disease
0.793 0.207 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.792 0.208 0.000
D72 Other disorders of white blood cells
0.792 0.208 0.000
C67 Malignant neoplasm of bladder
0.792 0.208 0.000
M05 Seropositive rheumatoid arthritis
0.790 0.210 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.790 0.210 0.000
E11.3 With ophthalmic complications
0.788 0.212 0.000
C34.1 Upper lobe, bronchus or lung
0.788 0.212 0.000
M86-M90 Other osteopathies
0.787 0.213 0.000
I45.2 Bifascicular block
0.785 0.215 0.000
M06.3 Rheumatoid nodule
0.784 0.216 0.000
L40.9 Psoriasis, unspecified
0.784 0.216 0.000
S86 Injury of muscle and tendon at lower leg level
0.783 0.217 0.000
E10.3 With ophthalmic complications
0.783 0.217 0.000
I21.9 Acute myocardial infarction, unspecified
0.782 0.218 0.000
I38 Endocarditis, valve unspecified
0.781 0.219 0.000
I72 Other aneurysm
0.779 0.221 0.000
E53 Deficiency of other B group vitamins
0.779 0.221 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.778 0.222 0.000
I73 Other peripheral vascular diseases
0.777 0.223 0.000
E27 Other disorders of adrenal gland
0.776 0.224 0.000
Y40 Systemic antibiotics
0.776 0.224 0.000
C92.0 Acute myeloid leukaemia
0.776 0.224 0.000
E10.4 With neurological complications
0.775 0.225 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.775 0.225 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.774 0.226 0.000
R06.0 Dyspnoea
0.772 0.228 0.000
G30-G32 Other degenerative diseases of the nervous system
0.771 0.229 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.771 0.229 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.771 0.229 0.000
G81 Hemiplegia
0.769 0.231 0.000
S91 Open wound of ankle and foot
0.768 0.232 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.767 0.233 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.765 0.235 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.764 0.235 0.000
M24.0 Loose body in joint
0.763 0.237 0.000
A80-A89 Viral infections of the central nervous system
0.763 0.237 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.762 0.238 0.000
M13.9 Arthritis, unspecified
0.761 0.239 0.000
T68 Hypothermia
0.761 0.239 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.761 0.239 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.761 0.239 0.000
L90.0 Lichen sclerosus et atrophicus
0.760 0.240 0.000
D04 Carcinoma in situ of skin
0.759 0.241 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.759 0.241 0.000
Y43.0 Antiallergic and antiemetic drugs
0.758 0.241 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.758 0.242 0.000
G90-G99 Other disorders of the nervous system
0.758 0.242 0.000
I49.4 Other and unspecified premature depolarisation
0.757 0.243 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.756 0.244 0.000
E11.0 With coma
0.755 0.245 0.000
H71 Cholesteatoma of middle ear
0.755 0.245 0.000
X50-X57 Overexertion, travel and privation
0.754 0.246 0.000
H33.5 Other retinal detachments
0.754 0.246 0.000
C45 Mesothelioma
0.753 0.247 0.000
M46 Other inflammatory spondylopathies
0.752 0.248 0.000
Q66 Congenital deformities of feet
0.751 0.249 0.000
D80-D89 Certain disorders involving the immune mechanism
0.750 0.250 0.000
C90.0 Multiple myeloma
0.747 0.253 0.000
Q43 Other congenital malformations of intestine
0.747 0.253 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.746 0.254 0.000
M65-M68 Disorders of synovium and tendon
0.746 0.254 0.000
M62 Other disorders of muscle
0.746 0.254 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.746 0.254 0.000
H43-H45 Disorders of vitreous body and globe
0.746 0.254 0.000
I77.1 Stricture of artery
0.745 0.255 0.000
E11.8 With unspecified complications
0.744 0.256 0.000
V98-V99 Other and unspecified transport accidents
0.744 0.256 0.000
I22 Subsequent myocardial infarction
0.743 0.257 0.000
T87 Complications peculiar to reattachment and amputation
0.743 0.257 0.000
H21 Other disorders of iris and ciliary body
0.743 0.257 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.742 0.258 0.000
R50-R69 General symptoms and signs
0.742 0.258 0.000
T31 Burns classified according to extent of body surface involved
0.742 0.258 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.742 0.258 0.000
C71 Malignant neoplasm of brain
0.740 0.260 0.000
S70-S79 Injuries to the hip and thigh
0.740 0.260 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.740 0.260 0.000
Y43.3 Other antineoplastic drugs
0.740 0.260 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.739 0.261 0.000
J18.9 Pneumonia, unspecified
0.739 0.261 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.738 0.262 0.000
M21 Other acquired deformities of limbs
0.738 0.262 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.738 0.262 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.737 0.262 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.737 0.263 0.000
H90 Conductive and sensorineural hearing loss
0.737 0.263 0.000
E28 Ovarian dysfunction
0.737 0.263 0.000
Y48 Anaesthetics and therapeutic gases
0.737 0.263 0.000
V01-V09 Pedestrian injured in transport accident
0.737 0.263 0.000
H83 Other diseases of inner ear
0.737 0.263 0.000
E53.8 Deficiency of other specified B group vitamins
0.736 0.264 0.000
M91-M94 Chondropathies
0.736 0.264 0.000
I51.0 Cardiac septal defect, acquired
0.736 0.264 0.000
E13.9 Without complications
0.734 0.266 0.000
M45 Ankylosing spondylitis
0.734 0.266 0.000
S99 Other and unspecified injuries of ankle and foot
0.733 0.266 0.000
G70-G73 Diseases of myoneural junction and muscle
0.733 0.266 0.000
E87.0 Hyperosmolality and hypernatraemia
0.733 0.267 0.000
V40-V49 Car occupant injured in transport accident
0.733 0.267 0.000
B25-B34 Other viral diseases
0.732 0.267 0.000
W50-W64 Exposure to animate mechanical forces
0.732 0.268 0.000
M47.1 Other spondylosis with myelopathy
0.731 0.269 0.000
I70 Atherosclerosis
0.730 0.270 0.000
D55-D59 Haemolytic anaemias
0.729 0.271 0.000
C34.2 Middle lobe, bronchus or lung
0.729 0.271 0.000
L81 Other disorders of pigmentation
0.728 0.272 0.000
R09.1 Pleurisy
0.727 0.273 0.000
E22 Hyperfunction of pituitary gland
0.725 0.275 0.000
E10.5 With peripheral circulatory complications
0.725 0.275 0.000
Y57 Other and unspecified drugs and medicaments
0.725 0.275 0.000
M14 Arthropathies in other diseases classified elsewhere
0.724 0.276 0.000
D73 Diseases of spleen
0.724 0.276 0.000
M13.94 Arthritis, unspecified (Hand)
0.719 0.281 0.000
M34.8 Other forms of systemic sclerosis
0.718 0.282 0.000
J10 Influenza due to identified influenza virus
0.718 0.282 0.000
I45.8 Other specified conduction disorders
0.718 0.282 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.718 0.282 0.000
L84 Corns and callosities
0.718 0.282 0.000
G81.9 Hemiplegia, unspecified
0.717 0.283 0.000
E78.5 Hyperlipidaemia, unspecified
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
I51.6 Cardiovascular disease, unspecified
0.716 0.284 0.000
I51.5 Myocardial degeneration
0.716 0.284 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.716 0.284 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.716 0.284 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.716 0.284 0.000
E11.6 With other specified complications
0.716 0.284 0.000
G50 Disorders of trigeminal nerve
0.715 0.285 0.000
E11.5 With peripheral circulatory complications
0.715 0.285 0.000
M06.8 Other specified rheumatoid arthritis
0.714 0.286 0.000
M06.2 Rheumatoid bursitis
0.714 0.286 0.000
M06.1 Adult-onset Still's disease
0.714 0.286 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.714 0.286 0.000
M31.3 Wegener's granulomatosis
0.713 0.287 0.000
D03 Melanoma in situ
0.713 0.287 0.000
I73.0 Raynaud's syndrome
0.713 0.287 0.000
G25 Other extrapyramidal and movement disorders
0.713 0.287 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.712 0.287 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.712 0.287 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.712 0.287 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.712 0.288 0.000
I23 Certain current complications following acute myocardial infarction
0.712 0.288 0.000
E74 Other disorders of carbohydrate metabolism
0.712 0.288 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.712 0.288 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.712 0.288 0.000
S81.9 Open wound of lower leg, part unspecified
0.711 0.289 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.711 0.289 0.000
H74 Other disorders of middle ear and mastoid
0.711 0.289 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.710 0.289 0.000
C80 Malignant neoplasm without specification of site
0.710 0.290 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.710 0.290 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.710 0.290 0.000
I50.9 Heart failure, unspecified
0.709 0.291 0.000
H69 Other disorders of Eustachian tube
0.709 0.291 0.000
W00-W19 Falls
0.709 0.291 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.709 0.291 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.708 0.292 0.000
L83 Acanthosis nigricans
0.708 0.292 0.000
Q85 Phakomatoses, not elsewhere classified
0.707 0.293 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.707 0.293 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.707 0.293 0.000
M33 Dermatopolymyositis
0.707 0.293 0.000
M32 Systemic lupus erythematosus
0.707 0.293 0.000
M30 Polyarteritis nodosa and related conditions
0.707 0.293 0.000
T33-T35 Frostbite
0.707 0.293 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.707 0.293 0.000
T00-T07 Injuries involving multiple body regions
0.707 0.293 0.000
R59 Enlarged lymph nodes
0.707 0.293 0.000
I42 Cardiomyopathy
0.707 0.293 0.000
Q76 Congenital malformations of spine and bony thorax
0.706 0.293 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.706 0.294 0.000
L43 Lichen planus
0.705 0.294 0.000
E14.8 With unspecified complications
0.705 0.295 0.000
E14.7 With multiple complications
0.705 0.295 0.000
E14.6 With other specified complications
0.705 0.295 0.000
E14.5 With peripheral circulatory complications
0.705 0.295 0.000
E14.4 With neurological complications
0.705 0.295 0.000
E14.2 Withrenal complications
0.705 0.295 0.000
E14.1 With ketoacidosis
0.705 0.295 0.000
E14.0 With coma
0.705 0.295 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.705 0.295 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.705 0.295 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.704 0.296 0.000
A49 Bacterial infection of unspecified site
0.704 0.296 0.000
M06.4 Inflammatory polyarthropathy
0.704 0.296 0.000
E85.4 Organ-limited amyloidosis
0.704 0.296 0.000
D51 Vitamin B12 deficiency anaemia
0.703 0.297 0.000
H93 Other disorders of ear, not elsewhere classified
0.703 0.297 0.000
S10-S19 Injuries to the neck
0.702 0.297 0.000
D75 Other diseases of blood and blood-forming organs
0.702 0.297 0.000
R87 Abnormal findings in specimens from female genital organs
0.702 0.298 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.702 0.298 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.702 0.298 0.000
D60-D64 Aplastic and other anaemias
0.702 0.298 0.000
C88 Malignant immunoproliferative diseases
0.701 0.299 0.000
Y00-Y09 Assault
0.700 0.300 0.000
Y40.9 Systemic antibiotic, unspecified
0.700 0.300 0.000
G56 Mononeuropathies of upper limb
0.700 0.300 0.000
I45.6 Preexcitation syndrome
0.699 0.301 0.000
M24.02 Loose body in joint (Upper arm)
0.698 0.302 0.000
M06.0 Seronegative rheumatoid arthritis
0.698 0.302 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.698 0.302 0.000
Q35-Q37 Cleft lip and cleft palate
0.698 0.302 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.698 0.302 0.000
S89 Other and unspecified injuries of lower leg
0.698 0.302 0.000
I37 Pulmonary valve disorders
0.697 0.302 0.000
E11.2 With renal complications
0.697 0.302 0.000
I78 Diseases of capillaries
0.697 0.303 0.000
C32 Malignant neoplasm of larynx
0.697 0.303 0.000
L50-L54 Urticaria and erythema
0.697 0.303 0.000
M07.6 Other enteropathic arthropathies
0.697 0.303 0.000
M07.5 Arthropathy in ulcerative colitis
0.697 0.303 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.697 0.303 0.000
M07.2 Psoriatic spondylitis
0.697 0.303 0.000
M07.1 Arthritis mutilans
0.697 0.303 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.697 0.303 0.000
S00-S09 Injuries to the head
0.697 0.303 0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level
0.697 0.303 0.000
H36.0 Diabetic retinopathy
0.696 0.304 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.695 0.305 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.695 0.305 0.000
L10-L14 Bullous disorders
0.695 0.305 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.694 0.306 0.000
E10.8 With unspecified complications
0.693 0.307 0.000
E10.7 With multiple complications
0.693 0.307 0.000
E10.6 With other specified complications
0.693 0.307 0.000
E10.0 With coma
0.693 0.307 0.000
E84 Cystic fibrosis
0.693 0.307 0.000
E79 Disorders of purine and pyrimidine metabolism
0.693 0.307 0.000
E77 Disorders of glycoprotein metabolism
0.693 0.307 0.000
E76 Disorders of glycosaminoglycan metabolism
0.693 0.307 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.693 0.307 0.000
E72 Other disorders of amino-acid metabolism
0.693 0.307 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.693 0.307 0.000
E70 Disorders of aromatic amino-acid metabolism
0.693 0.307 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.693 0.307 0.000
E88 Other metabolic disorders
0.693 0.307 0.000
T79-T79 Certain early complications of trauma
0.692 0.308 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.692 0.308 0.000
I77.6 Arteritis, unspecified
0.692 0.308 0.000
B99-B99 Other infectious diseases
0.692 0.308 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.692 0.308 0.000
B65-B83 Helminthiases
0.692 0.308 0.000
B50-B64 Protozoal diseases
0.692 0.308 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.692 0.308 0.000
A75-A79 Rickettsioses
0.692 0.308 0.000
A70-A74 Other diseases caused by chlamydiae
0.692 0.308 0.000
A65-A69 Other spirochaetal diseases
0.692 0.308 0.000
A20-A28 Certain zoonotic bacterial diseases
0.692 0.308 0.000
A15-A19 Tuberculosis
0.692 0.308 0.000
E23.0 Hypopituitarism
0.691 0.308 0.000
L40.0 Psoriasis vulgaris
0.691 0.309 0.000
M47.86 Other spondylosis (Lumbar region)
0.691 0.309 0.000
J18.1 Lobar pneumonia, unspecified
0.691 0.309 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.690 0.310 0.000
D74 Methaemoglobinaemia
0.690 0.310 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.690 0.310 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.690 0.310 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.689 0.310 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.689 0.311 0.000
M31.9 Necrotising vasculopathy, unspecified
0.689 0.311 0.000
M31.8 Other specified necrotising vasculopathies
0.689 0.311 0.000
M31.7 Microscopic polyangiitis
0.689 0.311 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.689 0.311 0.000
M31.2 Lethal midline granuloma
0.689 0.311 0.000
M31.1 Thrombotic microangiopathy
0.689 0.311 0.000
M31.0 Hypersensitivity angiitis
0.689 0.311 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.689 0.311 0.000
H34 Retinal vascular occlusions
0.689 0.311 0.000
H83.0 Labyrinthitis
0.688 0.312 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.688 0.312 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.687 0.313 0.000
R53 Malaise and fatigue
0.687 0.313 0.000
A41 Other septicaemia
0.686 0.314 0.000
I09 Other rheumatic heart diseases
0.686 0.314 0.000
I06 Rheumatic aortic valve diseases
0.686 0.314 0.000
R03.1 Nonspecific low blood-pressure reading
0.686 0.314 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.686 0.314 0.000
H18 Other disorders of cornea
0.686 0.314 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.685 0.315 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.684 0.316 0.000
L44 Other papulosquamous disorders
0.684 0.316 0.000
L41 Parapsoriasis
0.684 0.316 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.684 0.316 0.000
L42 Pityriasis rosea
0.684 0.316 0.000
M47.82 Other spondylosis (Cervical region)
0.684 0.316 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.683 0.317 0.000
C67.2 Lateral wall of bladder
0.683 0.317 0.000
M07.38 Other psoriatic arthropathies (Other)
0.682 0.317 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.682 0.317 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.682 0.317 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.682 0.317 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.682 0.317 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.682 0.317 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.682 0.317 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.682 0.317 0.000
M10 Gout
0.682 0.317 0.000
M47.9 Spondylosis, unspecified
0.682 0.318 0.000
A07 Other protozoal intestinal diseases
0.682 0.318 0.000
A06 Amoebiasis
0.682 0.318 0.000
A05 Other bacterial foodborne intoxications
0.682 0.318 0.000
A03 Shigellosis
0.682 0.318 0.000
A01 Typhoid and paratyphoid fevers
0.682 0.318 0.000
A00 Cholera
0.682 0.318 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.681 0.319 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.681 0.319 0.000
C31 Malignant neoplasm of accessory sinuses
0.681 0.319 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.681 0.319 0.000
C37 Malignant neoplasm of thymus
0.681 0.319 0.000
C33 Malignant neoplasm of trachea
0.681 0.319 0.000
I25.3 Aneurysm of heart
0.681 0.319 0.000
M49 Spondylopathies in diseases classified elsewhere
0.681 0.319 0.000
M00-M03 Infectious arthropathies
0.680 0.320 0.000
E10.2 With renal complications
0.680 0.320 0.000
R06.5 Mouth breathing
0.680 0.320 0.000
J00-J06 Acute upper respiratory infections
0.679 0.321 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.679 0.321 0.000
Y35-Y36 Legal intervention and operations of war
0.679 0.321 0.000
Y10-Y34 Event of undetermined intent
0.679 0.321 0.000
X85-X99 Assault
0.679 0.321 0.000
X30-X39 Exposure to forces of nature
0.679 0.321 0.000
X10-X19 Contact with heat and hot substances
0.679 0.321 0.000
X00-X09 Exposure to smoke, fire and flames
0.679 0.321 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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