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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34783620
log Bayes Factor = 20.3769
Chromosome 4   position 81,191,853  (GRCh37) Explore rs34783620 on Ensembl!
Variant rs34783620 is part of Cluster X0253

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.996 0.004 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.994 0.006 0.000
M70-M79 Other soft tissue disorders
0.991 0.009 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.987 0.013 0.000
Chapter XXI Factors influencing health status and contact with health services
0.981 0.019 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.980 0.020 0.000
F41 Other anxiety disorders
0.977 0.023 0.000
R50-R69 General symptoms and signs
0.975 0.025 0.000
M75 Shoulder lesions
0.971 0.029 0.000
C78.0 Secondary malignant neoplasm of lung
0.968 0.032 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.966 0.034 0.000
Chapter I Certain infectious and parasitic diseases
0.964 0.036 0.000
Chapter XX External causes of morbidity and mortality
0.962 0.038 0.000
R63 Symptoms and signs concerning food and fluid intake
0.960 0.040 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.959 0.041 0.000
I44 Atrioventricular and left bundle-branch block
0.956 0.044 0.000
O60-O75 Complications of labour and delivery
0.954 0.046 0.000
I73 Other peripheral vascular diseases
0.954 0.046 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.954 0.046 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.949 0.051 0.000
B95-B98 Bacterial, viral and other infectious agents
0.948 0.052 0.000
I50 Heart failure
0.947 0.053 0.000
Chapter XIV Diseases of the genitourinary system
0.947 0.053 0.000
M05-M14 Inflammatory polyarthropathies
0.946 0.054 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.945 0.055 0.000
W00-W19 Falls
0.945 0.055 0.000
I42 Cardiomyopathy
0.943 0.057 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.939 0.061 0.000
R63.4 Abnormal weight loss
0.938 0.062 0.000
R59 Enlarged lymph nodes
0.931 0.069 0.000
I51 Complications and ill-defined descriptions of heart disease
0.929 0.071 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.929 0.071 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.929 0.071 0.000
W19 Unspecified fall
0.928 0.072 0.000
I73.9 Peripheral vascular disease, unspecified
0.927 0.073 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.924 0.076 0.000
O70 Perineal laceration during delivery
0.923 0.077 0.000
C15-C26 Malignant neoplasms of digestive organs
0.922 0.078 0.000
N17-N19 Renal failure
0.920 0.080 0.000
M13 Other arthritis
0.918 0.082 0.000
W19.9 Unspecified place
0.917 0.083 0.000
O70.0 First degree perineal laceration during delivery
0.913 0.087 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.910 0.090 0.000
N40-N51 Diseases of male genital organs
0.907 0.093 0.000
C78.7 Secondary malignant neoplasm of liver
0.906 0.094 0.000
I83 Varicose veins of lower extremities
0.904 0.096 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.901 0.099 0.000
I20-I25 Ischaemic heart diseases
0.901 0.099 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.898 0.102 0.000
R42 Dizziness and giddiness
0.895 0.105 0.000
F17.1 Harmful use
0.895 0.105 0.000
M13.9 Arthritis, unspecified
0.894 0.106 0.000
I74 Arterial embolism and thrombosis
0.893 0.107 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.892 0.108 0.000
R11 Nausea and vomiting
0.892 0.108 0.000
I47 Paroxysmal tachycardia
0.888 0.112 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.886 0.114 0.000
Chapter XI Diseases of the digestive system
0.884 0.116 0.000
I60-I69 Cerebrovascular diseases
0.883 0.117 0.000
F41.2 Mixed anxiety and depressive disorder
0.883 0.117 0.000
N17 Acute renal failure
0.880 0.120 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.880 0.120 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.880 0.120 0.000
I50.9 Heart failure, unspecified
0.879 0.121 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.878 0.122 0.000
E70-E90 Metabolic disorders
0.878 0.122 0.000
Z96 Presence of other functional implants
0.877 0.123 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.876 0.124 0.000
S00-S09 Injuries to the head
0.874 0.126 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.873 0.127 0.000
R10 Abdominal and pelvic pain
0.872 0.128 0.000
M75.4 Impingement syndrome of shoulder
0.870 0.130 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.870 0.130 0.000
Chapter VI Diseases of the nervous system
0.870 0.130 0.000
I49 Other cardiac arrhythmias
0.868 0.132 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.868 0.132 0.000
Z96.6 Presence of orthopaedic joint implants
0.867 0.133 0.000
M72 Fibroblastic disorders
0.865 0.135 0.000
N10-N16 Renal tubulo-interstitial diseases
0.862 0.138 0.000
Z93 Artificial opening status
0.861 0.139 0.000
I42.0 Dilated cardiomyopathy
0.861 0.139 0.000
I44.1 Atrioventricular block, second degree
0.860 0.140 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.860 0.140 0.000
Z92 Personal history of medical treatment
0.859 0.141 0.000
E00-E07 Disorders of thyroid gland
0.855 0.145 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.854 0.146 0.000
N17.9 Acute renal failure, unspecified
0.852 0.148 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.852 0.148 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.851 0.149 0.000
I51.8 Other ill-defined heart diseases
0.851 0.149 0.000
R59.1 Generalised enlarged lymph nodes
0.850 0.150 0.000
E86 Volume depletion
0.847 0.153 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.847 0.153 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.844 0.156 0.000
R10.4 Other and unspecified abdominal pain
0.843 0.157 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.836 0.164 0.000
M75.5 Bursitis of shoulder
0.833 0.167 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.828 0.172 0.000
C60-C63 Malignant neoplasms of male genital organs
0.823 0.177 0.000
I77 Other disorders of arteries and arterioles
0.823 0.177 0.000
C79 Secondary malignant neoplasm of other sites
0.822 0.178 0.000
R63.0 Anorexia
0.819 0.181 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.815 0.185 0.000
F30-F39 Mood [affective] disorders
0.815 0.185 0.000
I42.9 Cardiomyopathy, unspecified
0.813 0.187 0.000
I85 Oesophageal varices
0.812 0.188 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.811 0.189 0.000
I78 Diseases of capillaries
0.810 0.190 0.000
M75.0 Adhesive capsulitis of shoulder
0.810 0.190 0.000
S01 Open wound of head
0.809 0.191 0.000
Chapter X Diseases of the respiratory system
0.807 0.193 0.000
I21 Acute myocardial infarction
0.807 0.193 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.805 0.195 0.000
I44.0 Atrioventricular block, first degree
0.804 0.196 0.000
R54 Senility
0.803 0.197 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.800 0.200 0.000
R59.0 Localised enlarged lymph nodes
0.799 0.201 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.798 0.202 0.000
K55-K64 Other diseases of intestines
0.797 0.203 0.000
Z94 Transplanted organ and tissue status
0.796 0.204 0.000
M71 Other bursopathies
0.795 0.204 0.000
R25 Abnormal involuntary movements
0.794 0.206 0.000
N18 Chronic renal failure
0.793 0.207 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.792 0.208 0.000
R30-R39 Symptoms and signs involving the urinary system
0.789 0.211 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.789 0.211 0.000
E03 Other hypothyroidism
0.787 0.213 0.000
K63 Other diseases of intestine
0.787 0.213 0.000
I25 Chronic ischaemic heart disease
0.786 0.214 0.000
R60 Oedema, not elsewhere classified
0.786 0.214 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.786 0.214 0.000
I44.3 Other and unspecified atrioventricular block
0.784 0.216 0.000
I50.1 Left ventricular failure
0.784 0.216 0.000
N48 Other disorders of penis
0.783 0.217 0.000
N50 Other disorders of male genital organs
0.783 0.217 0.000
M75.3 Calcific tendinitis of shoulder
0.782 0.218 0.000
M75.1 Rotator cuff syndrome
0.782 0.218 0.000
N25-N29 Other disorders of kidney and ureter
0.782 0.218 0.000
C15 Malignant neoplasm of oesophagus
0.780 0.220 0.000
R55 Syncope and collapse
0.778 0.222 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.778 0.222 0.000
I61 Intracerebral haemorrhage
0.776 0.224 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.776 0.224 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.775 0.225 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.774 0.226 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.773 0.227 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.773 0.227 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.771 0.229 0.000
I70 Atherosclerosis
0.770 0.230 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.770 0.230 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.769 0.231 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.769 0.231 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.769 0.231 0.000
M86-M90 Other osteopathies
0.769 0.231 0.000
I21.9 Acute myocardial infarction, unspecified
0.766 0.234 0.000
Chapter VIII Diseases of the ear and mastoid process
0.764 0.236 0.000
F17.2 Dependence syndrome
0.763 0.237 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.762 0.238 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.761 0.239 0.000
K63.5 Polyp of colon
0.761 0.239 0.000
C78.2 Secondary malignant neoplasm of pleura
0.758 0.242 0.000
F41.1 Generalised anxiety disorder
0.758 0.242 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.758 0.242 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.757 0.243 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.757 0.243 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.757 0.243 0.000
I51.7 Cardiomegaly
0.756 0.244 0.000
M45-M49 Spondylopathies
0.756 0.244 0.000
M65-M68 Disorders of synovium and tendon
0.755 0.245 0.000
K50-K52 Noninfective enteritis and colitis
0.755 0.245 0.000
I44.7 Left bundle-branch block, unspecified
0.755 0.245 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.755 0.245 0.000
R80 Isolated proteinuria
0.754 0.246 0.000
Z88.0 Personal history of allergy to penicillin
0.753 0.247 0.000
G90-G99 Other disorders of the nervous system
0.753 0.247 0.000
Z92.3 Personal history of irradiation
0.749 0.251 0.000
O80-O84 Delivery
0.749 0.251 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.749 0.251 0.000
I67 Other cerebrovascular diseases
0.747 0.253 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.747 0.253 0.000
C25 Malignant neoplasm of pancreas
0.746 0.254 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.745 0.255 0.000
M50-M54 Other dorsopathies
0.744 0.256 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.744 0.256 0.000
Z81 Family history of mental and behavioural disorders
0.743 0.257 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.743 0.257 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.742 0.258 0.000
E40-E46 Malnutrition
0.742 0.258 0.000
G20-G26 Extrapyramidal and movement disorders
0.740 0.260 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.740 0.260 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.740 0.260 0.000
O62 Abnormalities of forces of labour
0.740 0.260 0.000
I45 Other conduction disorders
0.739 0.261 0.000
I25.2 Old myocardial infarction
0.739 0.261 0.000
E03.9 Hypothyroidism, unspecified
0.739 0.261 0.000
Z93.2 Ileostomy status
0.738 0.262 0.000
I38 Endocarditis, valve unspecified
0.738 0.262 0.000
E50-E64 Other nutritional deficiencies
0.737 0.263 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.737 0.263 0.000
M40-M43 Deforming dorsopathies
0.737 0.263 0.000
F99-F99 Unspecified mental disorder
0.737 0.263 0.000
I60 Subarachnoid haemorrhage
0.736 0.264 0.000
I49.9 Cardiac arrhythmia, unspecified
0.736 0.264 0.000
R47-R49 Symptoms and signs involving speech and voice
0.735 0.265 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.734 0.266 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.733 0.267 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.731 0.269 0.000
Z95.0 Presence of cardiac pacemaker
0.727 0.273 0.000
R59.9 Enlarged lymph nodes, unspecified
0.726 0.274 0.000
I47.1 Supraventricular tachycardia
0.726 0.274 0.000
R52 Pain, not elsewhere classified
0.725 0.275 0.000
C18 Malignant neoplasm of colon
0.725 0.275 0.000
O66 Other obstructed labour
0.724 0.276 0.000
C80 Malignant neoplasm without specification of site
0.724 0.276 0.000
S40-S49 Injuries to the shoulder and upper arm
0.723 0.277 0.000
R40 Somnolence, stupor and coma
0.723 0.277 0.000
R33 Retention of urine
0.722 0.278 0.000
F40 Phobic anxiety disorders
0.721 0.279 0.000
W07 Fall involving chair
0.721 0.279 0.000
I85.9 Oesophageal varices without bleeding
0.721 0.279 0.000
K02 Dental caries
0.721 0.279 0.000
K50 Crohn's disease [regional enteritis]
0.720 0.279 0.000
D50-D53 Nutritional anaemias
0.720 0.280 0.000
Z83 Family history of other specific disorders
0.718 0.282 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.718 0.282 0.000
R17 Unspecified jaundice
0.718 0.282 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.718 0.282 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.283 0.000
F80-F89 Disorders of psychological development
0.716 0.283 0.000
F70-F79 Mental retardation
0.716 0.283 0.000
F60-F69 Disorders of adult personality and behaviour
0.716 0.283 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
M91-M94 Chondropathies
0.715 0.284 0.000
M60-M63 Disorders of muscles
0.715 0.284 0.000
M00-M03 Infectious arthropathies
0.715 0.284 0.000
I71 Aortic aneurysm and dissection
0.715 0.285 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.714 0.286 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.714 0.286 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.714 0.286 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.714 0.286 0.000
W06 Fall involving bed
0.714 0.286 0.000
I47.2 Ventricular tachycardia
0.714 0.286 0.000
S02 Fracture of skull and facial bones
0.714 0.286 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.713 0.287 0.000
N41 Inflammatory diseases of prostate
0.713 0.287 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.712 0.287 0.000
I72 Other aneurysm
0.712 0.287 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.712 0.288 0.000
M77 Other enthesopathies
0.711 0.289 0.000
M76 Enthesopathies of lower limb, excluding foot
0.711 0.289 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.711 0.289 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.711 0.289 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.710 0.290 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.710 0.290 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.710 0.290 0.000
N48.6 Balanitis xerotica obliterans
0.709 0.291 0.000
J00-J06 Acute upper respiratory infections
0.709 0.291 0.000
M05 Seropositive rheumatoid arthritis
0.708 0.291 0.000
F48 Other neurotic disorders
0.707 0.293 0.000
F45 Somatoform disorders
0.707 0.293 0.000
F44 Dissociative [conversion] disorders
0.707 0.293 0.000
F43 Reaction to severe stress, and adjustment disorders
0.707 0.293 0.000
F42 Obsessive-compulsive disorder
0.707 0.293 0.000
I50.0 Congestive heart failure
0.707 0.293 0.000
X60-X84 Intentional self-harm
0.707 0.293 0.000
S32 Fracture of lumbar spine and pelvis
0.707 0.293 0.000
W19.2 School, other institution and public administrative area
0.706 0.294 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.706 0.294 0.000
Z93.6 Other artificial openings of urinary tract status
0.704 0.296 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.704 0.296 0.000
R45 Symptoms and signs involving emotional state
0.703 0.297 0.000
O85-O92 Complications predominantly related to the puerperium
0.703 0.297 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.702 0.298 0.000
E73 Lactose intolerance
0.702 0.298 0.000
M13.0 Polyarthritis, unspecified
0.701 0.299 0.000
S00 Superficial injury of head
0.701 0.299 0.000
F41.8 Other specified anxiety disorders
0.700 0.299 0.000
F41.3 Other mixed anxiety disorders
0.700 0.299 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.700 0.300 0.000
I49.4 Other and unspecified premature depolarisation
0.699 0.301 0.000
R68 Other general symptoms and signs
0.699 0.301 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.699 0.301 0.000
R62 Lack of expected normal physiological development
0.699 0.301 0.000
R57 Shock, not elsewhere classified
0.699 0.301 0.000
R64 Cachexia
0.699 0.301 0.000
R58 Haemorrhage, not elsewhere classified
0.699 0.301 0.000
C51-C58 Malignant neoplasms of female genital organs
0.698 0.302 0.000
I46 Cardiac arrest
0.698 0.302 0.000
B35-B49 Mycoses
0.698 0.302 0.000
I24 Other acute ischaemic heart diseases
0.698 0.302 0.000
C61 Malignant neoplasm of prostate
0.697 0.303 0.000
M75.8 Other shoulder lesions
0.696 0.303 0.000
M75.9 Shoulder lesion, unspecified
0.696 0.303 0.000
M75.2 Bicipital tendinitis
0.696 0.303 0.000
F03 Unspecified dementia
0.696 0.304 0.000
Z50 Care involving use of rehabilitation procedures
0.695 0.305 0.000
S70-S79 Injuries to the hip and thigh
0.694 0.306 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.694 0.306 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.693 0.307 0.000
I95 Hypotension
0.692 0.308 0.000
B99-B99 Other infectious diseases
0.691 0.309 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.691 0.309 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.691 0.309 0.000
B65-B83 Helminthiases
0.691 0.309 0.000
B50-B64 Protozoal diseases
0.691 0.309 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.691 0.309 0.000
B15-B19 Viral hepatitis
0.691 0.309 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.691 0.309 0.000
A80-A89 Viral infections of the central nervous system
0.691 0.309 0.000
A75-A79 Rickettsioses
0.691 0.309 0.000
A70-A74 Other diseases caused by chlamydiae
0.691 0.309 0.000
A65-A69 Other spirochaetal diseases
0.691 0.309 0.000
A20-A28 Certain zoonotic bacterial diseases
0.691 0.309 0.000
A15-A19 Tuberculosis
0.691 0.309 0.000
M07 Psoriatic and enteropathic arthropathies
0.691 0.309 0.000
Z12 Special screening examination for neoplasms
0.691 0.309 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.690 0.310 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.690 0.310 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.690 0.310 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.690 0.310 0.000
Y35-Y36 Legal intervention and operations of war
0.690 0.310 0.000
Y10-Y34 Event of undetermined intent
0.690 0.310 0.000
Y00-Y09 Assault
0.690 0.310 0.000
X85-X99 Assault
0.690 0.310 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.690 0.310 0.000
X50-X57 Overexertion, travel and privation
0.690 0.310 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.690 0.310 0.000
X30-X39 Exposure to forces of nature
0.690 0.310 0.000
X20-X29 Contact with venomous animals and plants
0.690 0.310 0.000
X10-X19 Contact with heat and hot substances
0.690 0.310 0.000
X00-X09 Exposure to smoke, fire and flames
0.690 0.310 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.690 0.310 0.000
W75-W84 Other accidental threats to breathing
0.690 0.310 0.000
W65-W74 Accidental drowning and submersion
0.690 0.310 0.000
W50-W64 Exposure to animate mechanical forces
0.690 0.310 0.000
V98-V99 Other and unspecified transport accidents
0.690 0.310 0.000
V95-V97 Air and space transport accidents
0.690 0.310 0.000
V90-V94 Water transport accidents
0.690 0.310 0.000
V80-V89 Other land transport accidents
0.690 0.310 0.000
V70-V79 Bus occupant injured in transport accident
0.690 0.310 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.690 0.310 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.690 0.310 0.000
V40-V49 Car occupant injured in transport accident
0.690 0.310 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.690 0.310 0.000
V20-V29 Motorcycle rider injured in transport accident
0.690 0.310 0.000
V01-V09 Pedestrian injured in transport accident
0.690 0.310 0.000
A30-A49 Other bacterial diseases
0.689 0.311 0.000
K50.9 Crohn's disease, unspecified
0.688 0.312 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.688 0.312 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.688 0.312 0.000
R63.5 Abnormal weight gain
0.688 0.312 0.000
R63.3 Feeding difficulties and mismanagement
0.688 0.312 0.000
R63.2 Polyphagia
0.688 0.312 0.000
R63.1 Polydipsia
0.688 0.312 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.688 0.312 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.688 0.312 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.688 0.312 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.688 0.312 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.688 0.312 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.688 0.312 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.688 0.312 0.000
F11 Mental and behavioural disorders due to use of opioids
0.688 0.312 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.687 0.313 0.000
K63.3 Ulcer of intestine
0.687 0.313 0.000
O47 False labour
0.686 0.313 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.686 0.314 0.000
S90-S99 Injuries to the ankle and foot
0.685 0.315 0.000
I44.6 Other and unspecified fascicular block
0.685 0.315 0.000
I44.5 Left posterior fascicular block
0.685 0.315 0.000
I44.4 Left anterior fascicular block
0.685 0.315 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.685 0.315 0.000
E20-E35 Disorders of other endocrine glands
0.685 0.315 0.000
R30 Pain associated with micturition
0.684 0.316 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.684 0.316 0.000
O74 Complications of anaesthesia during labour and delivery
0.684 0.316 0.000
O73 Retained placenta and membranes, without haemorrhage
0.684 0.316 0.000
O71 Other obstetric trauma
0.684 0.316 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.684 0.316 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.684 0.316 0.000
O61 Failed induction of labour
0.684 0.316 0.000
O60 Preterm delivery
0.684 0.316 0.000
I73.8 Other specified peripheral vascular diseases
0.684 0.316 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.684 0.316 0.000
R46 Symptoms and signs involving appearance and behaviour
0.684 0.316 0.000
R43 Disturbances of smell and taste
0.684 0.316 0.000
J40-J47 Chronic lower respiratory diseases
0.683 0.317 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.683 0.317 0.000
C91 Lymphoid leukaemia
0.683 0.317 0.000
D00-D09 In situ neoplasms
0.683 0.317 0.000
Z04 Examination and observation for other reasons
0.683 0.317 0.000
K90-K93 Other diseases of the digestive system
0.682 0.318 0.000
M11 Other crystal arthropathies
0.680 0.320 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.680 0.320 0.000
F31 Bipolar affective disorder
0.680 0.320 0.000
Z40 Prophylactic surgery
0.679 0.321 0.000
O43 Placental disorders
0.679 0.321 0.000
I78.1 Naevus, nonneoplastic
0.679 0.321 0.000
S60-S69 Injuries to the wrist and hand
0.678 0.322 0.000
M14 Arthropathies in other diseases classified elsewhere
0.678 0.322 0.000
M12 Other specific arthropathies
0.678 0.322 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.678 0.322 0.000
M08 Juvenile arthritis
0.678 0.322 0.000
Z89 Acquired absence of limb
0.678 0.322 0.000
Z84 Family history of other conditions
0.678 0.322 0.000
R25.2 Cramp and spasm
0.678 0.322 0.000
W18 Other fall on same level
0.677 0.323 0.000
W17 Other fall from one level to another
0.677 0.323 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.677 0.323 0.000
W15 Fall from cliff
0.677 0.323 0.000
W14 Fall from tree
0.677 0.323 0.000
W13 Fall from, out of or through building or structure
0.677 0.323 0.000
W12 Fall on and from scaffolding
0.677 0.323 0.000
W11 Fall on and from ladder
0.677 0.323 0.000
W10 Fall on and from stairs and steps
0.677 0.323 0.000
W09 Fall involving playground equipment
0.677 0.323 0.000
W08 Fall involving other furniture
0.677 0.323 0.000
W05 Fall involving wheelchair
0.677 0.323 0.000
W04 Fall while being carried or supported by other persons
0.677 0.323 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.677 0.323 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.677 0.323 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.677 0.323 0.000
W00 Fall on same level involving ice and snow
0.677 0.323 0.000
F01 Vascular dementia
0.677 0.323 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.677 0.323 0.000
I42.8 Other cardiomyopathies
0.676 0.324 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.676 0.324 0.000
I42.6 Alcoholic cardiomyopathy
0.676 0.324 0.000
I42.5 Other restrictive cardiomyopathy
0.676 0.324 0.000
I42.4 Endocardial fibroelastosis
0.676 0.324 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.676 0.324 0.000
I42.2 Other hypertrophic cardiomyopathy
0.676 0.324 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.676 0.324 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.676 0.324 0.000
O41 Other disorders of amniotic fluid and membranes
0.675 0.325 0.000
M20-M25 Other joint disorders
0.675 0.325 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.674 0.325 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.674 0.326 0.000
I51.9 Heart disease, unspecified
0.673 0.327 0.000
S01.2 Open wound of nose
0.673 0.327 0.000
I88 Nonspecific lymphadenitis
0.673 0.327 0.000
I87 Other disorders of veins
0.673 0.327 0.000
I86 Varicose veins of other sites
0.673 0.327 0.000
I82 Other venous embolism and thrombosis
0.673 0.327 0.000
I81 Portal vein thrombosis
0.673 0.327 0.000
K02.9 Dental caries, unspecified
0.672 0.328 0.000
O42 Premature rupture of membranes
0.672 0.328 0.000
K65-K67 Diseases of peritoneum
0.671 0.329 0.000
I74.5 Embolism and thrombosis of iliac artery
0.671 0.329 0.000
Z94.8 Other transplanted organ and tissue status
0.671 0.329 0.000
R26 Abnormalities of gait and mobility
0.670 0.329 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.670 0.330 0.000
R10.1 Pain localised to upper abdomen
0.670 0.330 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.669 0.331 0.000
F00 Dementia in Alzheimer's disease
0.669 0.331 0.000
I73.0 Raynaud's syndrome
0.668 0.331 0.000
O36 Maternal care for other known or suspected foetal problems
0.668 0.332 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.667 0.333 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.667 0.333 0.000
S01.8 Open wound of other parts of head
0.667 0.333 0.000
T66-T78 Other and unspecified effects of external causes
0.667 0.333 0.000
I51.6 Cardiovascular disease, unspecified
0.666 0.334 0.000
I51.5 Myocardial degeneration
0.666 0.334 0.000
I51.4 Myocarditis, unspecified
0.666 0.334 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.666 0.334 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.666 0.334 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.666 0.334 0.000
I51.0 Cardiac septal defect, acquired
0.666 0.334 0.000
F17.9 Unspecified mental and behavioural disorder
0.666 0.334 0.000
F17.8 Other mental and behavioural disorders
0.666 0.334 0.000
F17.7 Residual and late-onset psychotic disorder
0.666 0.334 0.000
F17.6 Amnesic syndrome
0.666 0.334 0.000
F17.5 Psychotic disorder
0.666 0.334 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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