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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35010022
log Bayes Factor = 11.7386
Chromosome 22   position 41,045,892  (GRCh37) Explore rs35010022 on Ensembl!
Variant rs35010022 is part of Cluster X0052

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
S00-S09 Injuries to the head
0.995 0.005 0.000
O60-O75 Complications of labour and delivery
0.994 0.006 0.000
Chapter V Mental and behavioural disorders
0.988 0.012 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.978 0.022 0.000
E11.4 With neurological complications
0.970 0.030 0.000
E10 Insulin-dependent diabetes mellitus
0.966 0.034 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.963 0.037 0.000
E11.3 With ophthalmic complications
0.963 0.037 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.961 0.039 0.000
Chapter I Certain infectious and parasitic diseases
0.958 0.042 0.000
S00 Superficial injury of head
0.958 0.042 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.955 0.045 0.000
S09 Other and unspecified injuries of head
0.954 0.046 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.953 0.047 0.000
E70-E90 Metabolic disorders
0.953 0.047 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.950 0.050 0.000
E86 Volume depletion
0.942 0.058 0.000
O26.8 Other specified pregnancy-related conditions
0.942 0.058 0.000
F30-F39 Mood [affective] disorders
0.938 0.062 0.000
Chapter VII Diseases of the eye and adnexa
0.931 0.069 0.000
S50-S59 Injuries to the elbow and forearm
0.927 0.073 0.000
E11.2 With renal complications
0.925 0.075 0.000
W00-W19 Falls
0.925 0.075 0.000
O70 Perineal laceration during delivery
0.923 0.077 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.918 0.082 0.000
A00-A09 Intestinal infectious diseases
0.914 0.086 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.914 0.086 0.000
F45 Somatoform disorders
0.914 0.086 0.000
S09.9 Unspecified injury of head
0.909 0.091 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.905 0.095 0.000
E11.5 With peripheral circulatory complications
0.900 0.100 0.000
R25 Abnormal involuntary movements
0.899 0.101 0.000
F31 Bipolar affective disorder
0.893 0.107 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.892 0.108 0.000
S00.0 Superficial injury of scalp
0.888 0.112 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.887 0.113 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.886 0.114 0.000
F45.8 Other somatoform disorders
0.886 0.114 0.000
H53-H54 Visual disturbances and blindness
0.883 0.117 0.000
S40-S49 Injuries to the shoulder and upper arm
0.880 0.120 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.879 0.121 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.877 0.123 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.875 0.125 0.000
S80-S89 Injuries to the knee and lower leg
0.874 0.126 0.000
S70-S79 Injuries to the hip and thigh
0.874 0.126 0.000
O70.1 Second degree perineal laceration during delivery
0.871 0.129 0.000
F03 Unspecified dementia
0.871 0.129 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.865 0.135 0.000
R41.0 Disorientation, unspecified
0.864 0.136 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.863 0.137 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.862 0.138 0.000
M80-M85 Disorders of bone density and structure
0.861 0.139 0.000
O72 Postpartum haemorrhage
0.860 0.140 0.000
M81 Osteoporosis without pathological fracture
0.856 0.144 0.000
E10.4 With neurological complications
0.855 0.145 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.855 0.145 0.000
B35-B49 Mycoses
0.854 0.146 0.000
M81.9 Osteoporosis, unspecified
0.853 0.147 0.000
O85-O92 Complications predominantly related to the puerperium
0.843 0.157 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.842 0.158 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.841 0.159 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.840 0.160 0.000
S00.8 Superficial injury of other parts of head
0.838 0.162 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.836 0.164 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.836 0.164 0.000
Chapter XXII Codes for special purposes
0.834 0.166 0.000
W20-W49 Exposure to inanimate mechanical forces
0.831 0.169 0.000
S10-S19 Injuries to the neck
0.829 0.171 0.000
V40-V49 Car occupant injured in transport accident
0.828 0.172 0.000
R47-R49 Symptoms and signs involving speech and voice
0.826 0.174 0.000
O63 Long labour
0.826 0.174 0.000
R25.2 Cramp and spasm
0.826 0.174 0.000
R73 Elevated blood glucose level
0.823 0.177 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.823 0.177 0.000
S05 Injury of eye and orbit
0.822 0.178 0.000
E40-E46 Malnutrition
0.820 0.180 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.820 0.180 0.000
O66 Other obstructed labour
0.818 0.182 0.000
R25.1 Tremor, unspecified
0.818 0.182 0.000
E11.6 With other specified complications
0.817 0.183 0.000
E10.3 With ophthalmic complications
0.809 0.191 0.000
H43-H45 Disorders of vitreous body and globe
0.809 0.191 0.000
W19 Unspecified fall
0.808 0.192 0.000
E83 Disorders of mineral metabolism
0.808 0.192 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.807 0.193 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.803 0.197 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.801 0.199 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.800 0.200 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.799 0.201 0.000
Y00-Y09 Assault
0.797 0.203 0.000
Chapter VIII Diseases of the ear and mastoid process
0.797 0.203 0.000
O72.0 Third-stage haemorrhage
0.796 0.204 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.795 0.205 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.795 0.205 0.000
Chapter XXI Factors influencing health status and contact with health services
0.795 0.205 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.795 0.205 0.000
E10.2 With renal complications
0.794 0.206 0.000
H53 Visual disturbances
0.793 0.207 0.000
Y57 Other and unspecified drugs and medicaments
0.793 0.207 0.000
S01 Open wound of head
0.792 0.208 0.000
W06 Fall involving bed
0.790 0.210 0.000
O21 Excessive vomiting in pregnancy
0.790 0.210 0.000
S52 Fracture of forearm
0.789 0.211 0.000
E11.1 With ketoacidosis
0.788 0.212 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.788 0.212 0.000
S31 Open wound of abdomen, lower back and pelvis
0.786 0.214 0.000
S50 Superficial injury of forearm
0.786 0.214 0.000
Y84.2 Radiological procedure and radiotherapy
0.786 0.214 0.000
H54 Blindness and low vision
0.785 0.215 0.000
M80 Osteoporosis with pathological fracture
0.783 0.217 0.000
S00.1 Contusion of eyelid and periocular area
0.782 0.218 0.000
S09.8 Other specified injuries of head
0.781 0.219 0.000
W50-W64 Exposure to animate mechanical forces
0.781 0.219 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.780 0.220 0.000
E13 Other specified diabetes mellitus
0.780 0.220 0.000
O71 Other obstetric trauma
0.780 0.220 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.779 0.221 0.000
V20-V29 Motorcycle rider injured in transport accident
0.778 0.222 0.000
V10-V19 Pedal cyclist injured in transport accident
0.775 0.225 0.000
S30.1 Contusion of abdominal wall
0.775 0.225 0.000
R79 Other abnormal findings of blood chemistry
0.774 0.226 0.000
Y84.6 Urinary catheterisation
0.774 0.226 0.000
Y43 Primarily systemic agents
0.772 0.228 0.000
E10.1 With ketoacidosis
0.772 0.228 0.000
R49 Voice disturbances
0.767 0.233 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.767 0.233 0.000
X50-X57 Overexertion, travel and privation
0.766 0.234 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.766 0.234 0.000
F41 Other anxiety disorders
0.766 0.234 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.766 0.234 0.000
B15-B19 Viral hepatitis
0.764 0.236 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.763 0.237 0.000
O62 Abnormalities of forces of labour
0.760 0.240 0.000
W19.2 School, other institution and public administrative area
0.757 0.243 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.757 0.243 0.000
M86-M90 Other osteopathies
0.756 0.244 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.755 0.245 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.754 0.246 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.754 0.246 0.000
S60-S69 Injuries to the wrist and hand
0.753 0.247 0.000
E11.0 With coma
0.752 0.247 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.750 0.250 0.000
O20 Haemorrhage in early pregnancy
0.750 0.250 0.000
R26 Abnormalities of gait and mobility
0.749 0.251 0.000
O73 Retained placenta and membranes, without haemorrhage
0.749 0.251 0.000
R73.0 Abnormal glucose tolerance test
0.747 0.253 0.000
H50 Other strabismus
0.747 0.253 0.000
F42 Obsessive-compulsive disorder
0.747 0.253 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.747 0.253 0.000
F30 Manic episode
0.746 0.254 0.000
O26.2 Pregnancy care of habitual aborter
0.744 0.256 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.744 0.256 0.000
R25.3 Fasciculation
0.743 0.257 0.000
W17 Other fall from one level to another
0.742 0.257 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.741 0.259 0.000
B50-B64 Protozoal diseases
0.740 0.260 0.000
F33 Recurrent depressive disorder
0.739 0.261 0.000
O61 Failed induction of labour
0.738 0.262 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.738 0.262 0.000
F34 Persistent mood [affective] disorders
0.737 0.263 0.000
H30-H36 Disorders of choroid and retina
0.736 0.264 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.736 0.264 0.000
F43 Reaction to severe stress, and adjustment disorders
0.735 0.265 0.000
Y40 Systemic antibiotics
0.734 0.266 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.733 0.267 0.000
H44 Disorders of globe
0.729 0.271 0.000
X20-X29 Contact with venomous animals and plants
0.728 0.272 0.000
Z75 Problems related to medical facilities and other health care
0.725 0.275 0.000
R45 Symptoms and signs involving emotional state
0.724 0.276 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.723 0.277 0.000
Z33 Pregnant state, incidental
0.723 0.277 0.000
S51 Open wound of forearm
0.722 0.278 0.000
Y48 Anaesthetics and therapeutic gases
0.722 0.278 0.000
E10.5 With peripheral circulatory complications
0.722 0.278 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.720 0.280 0.000
A02 Other Salmonella infections
0.719 0.281 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.719 0.281 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.718 0.282 0.000
B37 Candidiasis
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.717 0.283 0.000
E11.8 With unspecified complications
0.716 0.283 0.000
E11.7 With multiple complications
0.716 0.283 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.716 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
H53.8 Other visual disturbances
0.716 0.284 0.000
S30.2 Contusion of external genital organs
0.715 0.284 0.000
S90-S99 Injuries to the ankle and foot
0.714 0.286 0.000
B99-B99 Other infectious diseases
0.714 0.286 0.000
R49.0 Dysphonia
0.714 0.286 0.000
S00.7 Multiple superficial injuries of head
0.714 0.286 0.000
R46 Symptoms and signs involving appearance and behaviour
0.713 0.287 0.000
S08 Traumatic amputation of part of head
0.713 0.287 0.000
S07 Crushing injury of head
0.713 0.287 0.000
S04 Injury of cranial nerves
0.713 0.287 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.713 0.287 0.000
O74 Complications of anaesthesia during labour and delivery
0.713 0.287 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.713 0.287 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.713 0.287 0.000
O60 Preterm delivery
0.713 0.287 0.000
O90 Complications of the puerperium, not elsewhere classified
0.713 0.287 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
Z34 Supervision of normal pregnancy
0.712 0.288 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.711 0.289 0.000
F60-F69 Disorders of adult personality and behaviour
0.711 0.289 0.000
F31.9 Bipolar affective disorder, unspecified
0.710 0.290 0.000
S52.0 Fracture of upper end of ulna
0.709 0.290 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.709 0.291 0.000
S00.9 Superficial injury of head, part unspecified
0.709 0.291 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.708 0.291 0.000
F70-F79 Mental retardation
0.708 0.291 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.708 0.292 0.000
A07 Other protozoal intestinal diseases
0.708 0.292 0.000
E10.9 Without complications
0.707 0.292 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.707 0.293 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.706 0.293 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.706 0.294 0.000
E85 Amyloidosis
0.706 0.294 0.000
S72 Fracture of femur
0.705 0.295 0.000
S01.9 Open wound of head, part unspecified
0.705 0.295 0.000
T66-T78 Other and unspecified effects of external causes
0.704 0.296 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.704 0.296 0.000
H36 Retinal disorders in diseases classified elsewhere
0.703 0.297 0.000
E20-E35 Disorders of other endocrine glands
0.702 0.298 0.000
S12 Fracture of neck
0.702 0.298 0.000
H54.4 Blindness, one eye
0.702 0.298 0.000
O29 Complications of anaesthesia during pregnancy
0.701 0.299 0.000
O28 Abnormal findings on antenatal screening of mother
0.701 0.299 0.000
O22 Venous complications in pregnancy
0.701 0.299 0.000
O25 Malnutrition in pregnancy
0.701 0.299 0.000
F99-F99 Unspecified mental disorder
0.700 0.300 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.700 0.300 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.700 0.300 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.698 0.302 0.000
Y84.0 Cardiac catheterisation
0.698 0.302 0.000
E16 Other disorders of pancreatic internal secretion
0.696 0.304 0.000
S42 Fracture of shoulder and upper arm
0.695 0.305 0.000
S79 Other and unspecified injuries of hip and thigh
0.694 0.306 0.000
B44 Aspergillosis
0.694 0.306 0.000
E10.8 With unspecified complications
0.693 0.307 0.000
E10.7 With multiple complications
0.693 0.307 0.000
E10.6 With other specified complications
0.693 0.307 0.000
E10.0 With coma
0.693 0.307 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.693 0.307 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.692 0.308 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.692 0.308 0.000
E46 Unspecified protein-energy malnutrition
0.692 0.308 0.000
S56 Injury of muscle and tendon at forearm level
0.691 0.309 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.691 0.309 0.000
Y59 Other and unspecified vaccines and biological substances
0.691 0.309 0.000
Y58 Bacterial vaccines
0.691 0.309 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.691 0.309 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.691 0.309 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.691 0.309 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.691 0.309 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.691 0.309 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.691 0.309 0.000
E73 Lactose intolerance
0.691 0.309 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.689 0.311 0.000
S37 Injury of urinary and pelvic organs
0.689 0.311 0.000
S36 Injury of intra-abdominal organs
0.689 0.311 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.689 0.311 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.689 0.311 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.689 0.311 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.689 0.311 0.000
V80-V89 Other land transport accidents
0.688 0.311 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.688 0.312 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.687 0.313 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.687 0.313 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.687 0.313 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.687 0.313 0.000
A75-A79 Rickettsioses
0.687 0.313 0.000
A70-A74 Other diseases caused by chlamydiae
0.687 0.313 0.000
A65-A69 Other spirochaetal diseases
0.687 0.313 0.000
A20-A28 Certain zoonotic bacterial diseases
0.687 0.313 0.000
A15-A19 Tuberculosis
0.687 0.313 0.000
S00.5 Superficial injury of lip and oral cavity
0.687 0.313 0.000
S00.4 Superficial injury of ear
0.687 0.313 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.687 0.313 0.000
Y84.1 Kidney dialysis
0.687 0.313 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.685 0.315 0.000
O26.5 Maternal hypotension syndrome
0.685 0.315 0.000
O26.4 Herpes gestationis
0.685 0.315 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.685 0.315 0.000
O26.1 Low weight gain in pregnancy
0.685 0.315 0.000
O26.0 Excessive weight gain in pregnancy
0.685 0.315 0.000
E83.1 Disorders of iron metabolism
0.685 0.315 0.000
S09.7 Multiple injuries of head
0.684 0.316 0.000
S09.2 Traumatic rupture of ear drum
0.684 0.316 0.000
S09.1 Injury of muscle and tendon of head
0.684 0.316 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.684 0.316 0.000
F48 Other neurotic disorders
0.683 0.316 0.000
F44 Dissociative [conversion] disorders
0.683 0.316 0.000
E84 Cystic fibrosis
0.683 0.317 0.000
E79 Disorders of purine and pyrimidine metabolism
0.683 0.317 0.000
E77 Disorders of glycoprotein metabolism
0.683 0.317 0.000
E76 Disorders of glycosaminoglycan metabolism
0.683 0.317 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.683 0.317 0.000
E74 Other disorders of carbohydrate metabolism
0.683 0.317 0.000
E72 Other disorders of amino-acid metabolism
0.683 0.317 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.683 0.317 0.000
E70 Disorders of aromatic amino-acid metabolism
0.683 0.317 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.683 0.317 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.683 0.317 0.000
W08 Fall involving other furniture
0.682 0.318 0.000
S86 Injury of muscle and tendon at lower leg level
0.682 0.318 0.000
R73.9 Hyperglycaemia, unspecified
0.681 0.319 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.681 0.319 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.680 0.320 0.000
H36.0 Diabetic retinopathy
0.680 0.320 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.678 0.322 0.000
R40 Somnolence, stupor and coma
0.678 0.322 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.678 0.322 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.677 0.323 0.000
O70.2 Third degree perineal laceration during delivery
0.676 0.324 0.000
H40-H42 Glaucoma
0.676 0.324 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.673 0.327 0.000
T17 Foreign body in respiratory tract
0.673 0.327 0.000
O24 Diabetes mellitus in pregnancy
0.673 0.327 0.000
O23 Infections of genito-urinary tract in pregnancy
0.673 0.327 0.000
O63.9 Long labour, unspecified
0.673 0.327 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.673 0.327 0.000
F38 Other mood [affective] disorders
0.672 0.328 0.000
F39 Unspecified mood [affective] disorder
0.672 0.328 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.672 0.328 0.000
F80-F89 Disorders of psychological development
0.672 0.328 0.000
H44.2 Degenerative myopia
0.672 0.328 0.000
S80 Superficial injury of lower leg
0.671 0.328 0.000
Y57.9 Drug or medicament, unspecified
0.670 0.330 0.000
Y44 Agents primarily affecting blood constituents
0.669 0.330 0.000
S82 Fracture of lower leg, including ankle
0.669 0.331 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.669 0.331 0.000
Y52 Agents primarily affecting the cardiovascular system
0.669 0.331 0.000
H53.0 Amblyopia ex anopsia
0.668 0.332 0.000
W18 Other fall on same level
0.666 0.334 0.000
H60-H62 Diseases of external ear
0.665 0.335 0.000
S59 Other and unspecified injuries of forearm
0.665 0.335 0.000
S58 Traumatic amputation of forearm
0.665 0.335 0.000
S57 Crushing injury of forearm
0.665 0.335 0.000
S55 Injury of blood vessels at forearm level
0.665 0.335 0.000
S54 Injury of nerves at forearm level
0.665 0.335 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.665 0.335 0.000
O63.1 Prolonged second stage (of labour)
0.664 0.336 0.000
S43.0 Dislocation of shoulder joint
0.664 0.336 0.000
S68 Traumatic amputation of wrist and hand
0.663 0.336 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.663 0.337 0.000
W15 Fall from cliff
0.663 0.337 0.000
W14 Fall from tree
0.663 0.337 0.000
W12 Fall on and from scaffolding
0.663 0.337 0.000
W11 Fall on and from ladder
0.663 0.337 0.000
W09 Fall involving playground equipment
0.663 0.337 0.000
W05 Fall involving wheelchair
0.663 0.337 0.000
W04 Fall while being carried or supported by other persons
0.663 0.337 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.663 0.337 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.663 0.337 0.000
W00 Fall on same level involving ice and snow
0.663 0.337 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.663 0.337 0.000
S01.3 Open wound of ear
0.663 0.337 0.000
T14 Injury of unspecified body region
0.662 0.338 0.000
O70.9 Perineal laceration during delivery, unspecified
0.662 0.338 0.000
O70.3 Fourth degree perineal laceration during delivery
0.662 0.338 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.660 0.340 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.660 0.340 0.000
S31.1 Open wound of abdominal wall
0.660 0.340 0.000
W13 Fall from, out of or through building or structure
0.659 0.341 0.000
M85 Other disorders of bone density and structure
0.659 0.341 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.659 0.341 0.000
W20 Struck by thrown, projected or falling object
0.659 0.341 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.658 0.342 0.000
S81 Open wound of lower leg
0.658 0.342 0.000
H50.9 Strabismus, unspecified
0.657 0.343 0.000
H54.0 Blindness, both eyes
0.657 0.343 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.656 0.344 0.000
A06 Amoebiasis
0.655 0.345 0.000
A05 Other bacterial foodborne intoxications
0.655 0.345 0.000
A03 Shigellosis
0.655 0.345 0.000
A01 Typhoid and paratyphoid fevers
0.655 0.345 0.000
A00 Cholera
0.655 0.345 0.000
F45.9 Somatoform disorder, unspecified
0.655 0.345 0.000
F45.4 Persistent somatoform pain disorder
0.655 0.345 0.000
F45.3 Somatoform autonomic dysfunction
0.655 0.345 0.000
F45.2 Hypochondriacal disorder
0.655 0.345 0.000
F45.1 Undifferentiated somatoform disorder
0.655 0.345 0.000
F45.0 Somatisation disorder
0.655 0.345 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.655 0.345 0.000
F02 Dementia in other diseases classified elsewhere
0.655 0.345 0.000
F09 Unspecified organic or symptomatic mental disorder
0.655 0.345 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.655 0.345 0.000
O21.0 Mild hyperemesis gravidarum
0.655 0.345 0.000
S71 Open wound of hip and thigh
0.655 0.345 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.654 0.346 0.000
E14 Unspecified diabetes mellitus
0.653 0.347 0.000
O70.0 First degree perineal laceration during delivery
0.651 0.349 0.000
Y45.2 Propionic acid derivatives
0.651 0.349 0.000
H50.0 Convergent concomitant strabismus
0.650 0.350 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.650 0.350 0.000
W06.9 Unspecified place
0.650 0.350 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.650 0.350 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.649 0.351 0.000
A80-A89 Viral infections of the central nervous system
0.649 0.351 0.000
R43 Disturbances of smell and taste
0.649 0.351 0.000
A08 Viral and other specified intestinal infections
0.649 0.351 0.000
S05.9 Injury of eye and orbit, part unspecified
0.648 0.351 0.000
S50.9 Superficial injury of forearm, unspecified
0.648 0.352 0.000
H65-H75 Diseases of middle ear and mastoid
0.648 0.352 0.000
E83.3 Disorders of phosphorus metabolism
0.647 0.352 0.000
S06 Intracranial injury
0.647 0.353 0.000
M00-M03 Infectious arthropathies
0.647 0.353 0.000
F41.1 Generalised anxiety disorder
0.646 0.354 0.000
T63 Toxic effect of contact with venomous animals
0.646 0.354 0.000
A30-A49 Other bacterial diseases
0.646 0.354 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.645 0.355 0.000
R25.0 Abnormal head movements
0.645 0.355 0.000
B35 Dermatophytosis
0.644 0.356 0.000
A04 Other bacterial intestinal infections
0.644 0.356 0.000
H53.4 Visual field defects
0.643 0.357 0.000
B95-B98 Bacterial, viral and other infectious agents
0.643 0.357 0.000
Q00-Q07 Congenital malformations of the nervous system
0.642 0.358 0.000
M91-M94 Chondropathies
0.641 0.359 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.640 0.360 0.000
F31.8 Other bipolar affective disorders
0.640 0.360 0.000
F31.7 Bipolar affective disorder, currently in remission
0.640 0.360 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.640 0.360 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.640 0.360 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.640 0.360 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.640 0.360 0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis
0.640 0.360 0.000
S30.0 Contusion of lower back and pelvis
0.640 0.360 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.639 0.361 0.000
O86 Other puerperal infections
0.638 0.362 0.000
S62 Fracture at wrist and hand level
0.638 0.362 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.638 0.362 0.000
S52.00 Fracture of upper end of ulna (closed)
0.637 0.363 0.000
R45.1 Restlessness and agitation
0.637 0.363 0.000
Z39 Postpartum care and examination
0.637 0.363 0.000
S41 Open wound of shoulder and upper arm
0.637 0.363 0.000
M81.98 Osteoporosis, unspecified (Other)
0.637 0.363 0.000
W22 Striking against or struck by other objects
0.636 0.364 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.636 0.364 0.000
R77 Other abnormalities of plasma proteins
0.636 0.364 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.636 0.364 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.636 0.364 0.000
R71 Abnormality of red blood cells
0.636 0.364 0.000
W06.0 Home
0.636 0.364 0.000
Y43.3 Other antineoplastic drugs
0.635 0.365 0.000
R50-R69 General symptoms and signs
0.635 0.365 0.000
Q80-Q89 Other congenital malformations
0.635 0.365 0.000
Z34.0 Supervision of normal first pregnancy
0.633 0.367 0.000
Y49.2 Other and unspecified antidepressants
0.632 0.368 0.000
S48 Traumatic amputation of shoulder and upper arm
0.631 0.369 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.631 0.369 0.000
S44 Injury of nerves at shoulder and upper arm level
0.631 0.369 0.000
S47 Crushing injury of shoulder and upper arm
0.631 0.369 0.000
W07 Fall involving chair
0.631 0.369 0.000
T59 Toxic effect of other gases, fumes and vapours
0.630 0.370 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.630 0.370 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.630 0.370 0.000
Q35-Q37 Cleft lip and cleft palate
0.630 0.370 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.630 0.370 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.630 0.370 0.000
M60-M63 Disorders of muscles
0.629 0.370 0.000
M87 Osteonecrosis
0.629 0.371 0.000
R41.2 Retrograde amnesia
0.629 0.371 0.000
R41.1 Anterograde amnesia
0.629 0.371 0.000
X60-X84 Intentional self-harm
0.628 0.372 0.000
X41.9 Unspecified place
0.628 0.372 0.000
Y49.5 Other antipsychotics and neuroleptics
0.627 0.372 0.000
T87 Complications peculiar to reattachment and amputation
0.627 0.373 0.000
S05.8 Other injuries of eye and orbit
0.627 0.373 0.000
S88 Traumatic amputation of lower leg
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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