TreeWAS – Variant ID: rs35383149

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.999	0.001
Chapter XX External causes of morbidity and mortality	0.997	0.003
S20-S29 Injuries to the thorax	0.997	0.003
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.997	0.003
S22 Fracture of rib(s), sternum and thoracic spine	0.993	0.007
S22.4 Multiple fractures of ribs	0.987	0.013
S60-S69 Injuries to the wrist and hand	0.984	0.016
Chapter VI Diseases of the nervous system	0.984	0.016
S22.40 Multiple fractures of ribs (closed)	0.983	0.017
M50-M54 Other dorsopathies	0.982	0.018
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.979	0.021
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.977	0.023
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.975	0.025
T81 Complications of procedures, not elsewhere classified	0.973	0.027
Chapter I Certain infectious and parasitic diseases	0.972	0.028
S40-S49 Injuries to the shoulder and upper arm	0.962	0.038
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.959	0.041
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.958	0.042
M51 Other intervertebral disk disorders	0.954	0.046
Y43 Primarily systemic agents	0.952	0.048
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.952	0.048
T81.4 Infection following a procedure, not elsewhere classified	0.951	0.049
A30-A49 Other bacterial diseases	0.948	0.052
S42 Fracture of shoulder and upper arm	0.944	0.056
Y43.3 Other antineoplastic drugs	0.932	0.068
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.930	0.070
R93 Abnormal findings on diagnostic imaging of other body structures	0.929	0.071
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.928	0.072
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.924	0.076
M20-M25 Other joint disorders	0.923	0.077
D70-D77 Other diseases of blood and blood-forming organs	0.921	0.079
T90 Sequelae of injuries of head	0.918	0.082
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.915	0.085
S27 Injury of other and unspecified intrathoracic organs	0.911	0.089
M25 Other joint disorders, not elsewhere classified	0.908	0.092
A41 Other septicaemia	0.907	0.093
S66 Injury of muscle and tendon at wrist and hand level	0.906	0.094
B35-B49 Mycoses	0.903	0.097
S61 Open wound of wrist and hand	0.901	0.099
G50-G59 Nerve, nerve root and plexus disorders	0.899	0.101
S10-S19 Injuries to the neck	0.897	0.103
S42.3 Fracture of shaft of humerus	0.895	0.105
M05-M14 Inflammatory polyarthropathies	0.890	0.110
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.887	0.113
M51.2 Other specified intervertebral disk displacement	0.887	0.113
S80-S89 Injuries to the knee and lower leg	0.884	0.116
M54 Dorsalgia	0.875	0.125
G40-G47 Episodic and paroxysmal disorders	0.873	0.127
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.871	0.129
S64 Injury of nerves at wrist and hand level	0.871	0.129
D70 Agranulocytosis	0.868	0.132
R94 Abnormal results of function studies	0.865	0.135
M80-M85 Disorders of bone density and structure	0.860	0.140
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.860	0.140
S42.30 Fracture of shaft of humerus (closed)	0.859	0.140
S70-S79 Injuries to the hip and thigh	0.859	0.141
D50-D53 Nutritional anaemias	0.858	0.142
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.854	0.146
G40 Epilepsy	0.854	0.146
M86-M90 Other osteopathies	0.853	0.147
S22.3 Fracture of rib	0.853	0.147
R23 Other skin changes	0.852	0.148
B37 Candidiasis	0.851	0.149
T20-T25 Burns and corrosions of external body surface, specified by site	0.844	0.156
S42.0 Fracture of clavicle	0.844	0.156
G00-G09 Inflammatory diseases of the central nervous system	0.843	0.157
V80-V89 Other land transport accidents	0.842	0.158
D60-D64 Aplastic and other anaemias	0.842	0.158
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.838	0.162
T80 Complications following infusion, transfusion and therapeutic injection	0.838	0.162
T90.4 Sequelae of injury of eye and orbit	0.834	0.166
Chapter XXII Codes for special purposes	0.830	0.170
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.829	0.171
A49 Bacterial infection of unspecified site	0.827	0.173
T87 Complications peculiar to reattachment and amputation	0.826	0.174
A41.0 Septicaemia due to Staphylococcus aureus	0.825	0.175
Y52 Agents primarily affecting the cardiovascular system	0.823	0.177
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.822	0.178
M25.5 Pain in joint	0.819	0.181
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.816	0.184
T93 Sequelae of injuries of lower limb	0.815	0.184
G40.9 Epilepsy, unspecified	0.810	0.190
T88 Other complications of surgical and medical care, not elsewhere classified	0.805	0.195
M84 Disorders of continuity of bone	0.805	0.195
R23.8 Other and unspecified skin changes	0.803	0.197
T81.7 Vascular complications following a procedure, not elsewhere classified	0.803	0.197
Y85 Sequelae of transport accidents	0.800	0.200
G80-G83 Cerebral palsy and other paralytic syndromes	0.799	0.201
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.799	0.201
R94.5 Abnormal results of liver function studies	0.798	0.202
R87 Abnormal findings in specimens from female genital organs	0.796	0.204
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.796	0.204
S27.0 Traumatic pneumothorax	0.796	0.204
S67 Crushing injury of wrist and hand	0.795	0.205
Y86 Sequelae of other accidents	0.795	0.205
V40-V49 Car occupant injured in transport accident	0.793	0.207
T85 Complications of other internal prosthetic devices, implants and grafts	0.792	0.208
R91 Abnormal findings on diagnostic imaging of lung	0.791	0.209
V20-V29 Motorcycle rider injured in transport accident	0.791	0.209
M54.2 Cervicalgia	0.789	0.211
D63 Anaemia in chronic diseases classified elsewhere	0.788	0.212
S66.8 Injury of other muscles and tendons at wrist and hand level	0.786	0.214
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.784	0.216
S61.0 Open wound of finger(s) without damage to nail	0.783	0.217
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.780	0.220
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.780	0.220
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.780	0.220
S12 Fracture of neck	0.780	0.220
B37.8 Candidiasis of other sites	0.778	0.222
W50-W64 Exposure to animate mechanical forces	0.775	0.225
S42.00 Fracture of clavicle (closed)	0.772	0.228
B37.0 Candidal stomatitis	0.771	0.229
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.770	0.229
G70-G73 Diseases of myoneural junction and muscle	0.770	0.230
M13 Other arthritis	0.770	0.230
D51 Vitamin B12 deficiency anaemia	0.769	0.231
S80 Superficial injury of lower leg	0.769	0.231
S42.1 Fracture of scapula	0.768	0.231
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.768	0.232
S64.4 Injury of digital nerve of other finger	0.767	0.233
S22.1 Multiple fractures of thoracic spine	0.766	0.234
T90.9 Sequelae of unspecified injury of head	0.762	0.238
M84.1 Nonunion of fracture [pseudarthrosis]	0.759	0.241
M89 Other disorders of bone	0.758	0.242
S90-S99 Injuries to the ankle and foot	0.755	0.245
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.755	0.245
M25.8 Other specified joint disorders	0.754	0.246
G20-G26 Extrapyramidal and movement disorders	0.753	0.247
T91 Sequelae of injuries of neck and trunk	0.753	0.247
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.753	0.247
S22.30 Fracture of rib (closed)	0.753	0.247
T98 Sequelae of other and unspecified effects of external causes	0.753	0.247
T81.3 Disruption of operation wound, not elsewhere classified	0.752	0.248
G35-G37 Demyelinating diseases of the central nervous system	0.752	0.248
G54 Nerve root and plexus disorders	0.752	0.248
D52 Folate deficiency anaemia	0.751	0.249
D75 Other diseases of blood and blood-forming organs	0.749	0.251
A40 Streptococcal septicaemia	0.748	0.252
S61.9 Open wound of wrist and hand, part unspecified	0.747	0.253
V10-V19 Pedal cyclist injured in transport accident	0.747	0.253
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.747	0.253
T94 Sequelae of injuries involving multiple and unspecified body regions	0.745	0.254
A41.9 Septicaemia, unspecified	0.745	0.255
Y43.0 Antiallergic and antiemetic drugs	0.745	0.255
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.745	0.255
S42.4 Fracture of lower end of humerus	0.745	0.255
M25.3 Other instability of joint	0.744	0.256
M51.9 Intervertebral disk disorder, unspecified	0.744	0.256
Y45.1 Salicylates	0.744	0.256
D63.0 Anaemia in neoplastic disease	0.744	0.256
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.744	0.256
X58-X59 Accidental exposure to other and unspecified factors	0.743	0.257
A41.1 Septicaemia due to other specified staphylococcus	0.743	0.257
G59 Mononeuropathy in diseases classified elsewhere	0.742	0.258
S27.3 Other injuries of lung	0.742	0.258
S40 Superficial injury of shoulder and upper arm	0.741	0.259
M25.4 Effusion of joint	0.740	0.260
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.740	0.260
X40-X49 Accidental poisoning by and exposure to noxious substances	0.739	0.261
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.739	0.261
T92 Sequelae of injuries of upper limb	0.737	0.263
T15-T19 Effects of foreign body entering through natural orifice	0.737	0.263
M25.7 Osteophyte	0.737	0.263
Chapter XII Diseases of the skin and subcutaneous tissue	0.736	0.264
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.735	0.265
R20 Disturbances of skin sensation	0.734	0.266
M32 Systemic lupus erythematosus	0.734	0.266
Y00-Y09 Assault	0.734	0.266
M70-M79 Other soft tissue disorders	0.733	0.267
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.731	0.269
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.731	0.269
M50 Cervical disk disorders	0.730	0.270
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.727	0.273
M60-M63 Disorders of muscles	0.727	0.273
M54.22 Cervicalgia (Cervical region)	0.726	0.274
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.725	0.275
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.723	0.277
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.722	0.278
M25.6 Stiffness of joint, not elsewhere classified	0.719	0.281
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.718	0.282
A41.2 Septicaemia due to unspecified staphylococcus	0.718	0.282
M40-M43 Deforming dorsopathies	0.718	0.282
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.718	0.282
G55.2 Nerve root and plexus compressions in spondylosis	0.718	0.282
T90.2 Sequelae of fracture of skull and facial bones	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
G04 Encephalitis, myelitis and encephalomyelitis	0.717	0.283
M23 Internal derangement of knee	0.716	0.284
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.715	0.285
Y35-Y36 Legal intervention and operations of war	0.715	0.285
Y10-Y34 Event of undetermined intent	0.715	0.285
X85-X99 Assault	0.715	0.285
X50-X57 Overexertion, travel and privation	0.715	0.285
X30-X39 Exposure to forces of nature	0.715	0.285
X20-X29 Contact with venomous animals and plants	0.715	0.285
X10-X19 Contact with heat and hot substances	0.715	0.285
X00-X09 Exposure to smoke, fire and flames	0.715	0.285
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.715	0.285
W75-W84 Other accidental threats to breathing	0.715	0.285
W65-W74 Accidental drowning and submersion	0.715	0.285
V98-V99 Other and unspecified transport accidents	0.715	0.285
V95-V97 Air and space transport accidents	0.715	0.285
V90-V94 Water transport accidents	0.715	0.285
V70-V79 Bus occupant injured in transport accident	0.715	0.285
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.715	0.285
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.715	0.285
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.715	0.285
V01-V09 Pedestrian injured in transport accident	0.715	0.285
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.715	0.285
S26 Injury of heart	0.715	0.285
S25 Injury of blood vessels of thorax	0.715	0.285
S24 Injury of nerves and spinal cord at thorax level	0.715	0.285
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.715	0.285
S21 Open wound of thorax	0.715	0.285
M25.54 Pain in joint (Hand)	0.713	0.287
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.713	0.287
S27.1 Traumatic haemothorax	0.712	0.288
S22.9 Fracture of bony thorax, part unspecified	0.712	0.288
S22.8 Fracture of other parts of bony thorax	0.712	0.288
S22.5 Flail chest	0.712	0.288
S71 Open wound of hip and thigh	0.711	0.289
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.710	0.290
M00-M03 Infectious arthropathies	0.709	0.291
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.708	0.291
S30 Superficial injury of abdomen, lower back and pelvis	0.708	0.292
Y85.0 Sequelae of motor-vehicle accident	0.708	0.292
S22.41 Multiple fractures of ribs (open)	0.707	0.292
R41 Other symptoms and signs involving cognitive functions and awareness	0.707	0.293
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.707	0.293
S00-S09 Injuries to the head	0.706	0.294
B90-B94 Sequelae of infectious and parasitic diseases	0.705	0.294
S65 Injury of blood vessels at wrist and hand level	0.705	0.295
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.702	0.298
T95 Sequelae of burns, corrosions and frostbite	0.700	0.299
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.700	0.299
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.700	0.299
R25 Abnormal involuntary movements	0.700	0.300
G30-G32 Other degenerative diseases of the nervous system	0.700	0.300
B99-B99 Other infectious diseases	0.700	0.300
S80.1 Contusion of other and unspecified parts of lower leg	0.700	0.300
G40.5 Special epileptic syndromes	0.699	0.301
Y59 Other and unspecified vaccines and biological substances	0.699	0.301
Y58 Bacterial vaccines	0.699	0.301
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.699	0.301
Y53 Agents primarily affecting the gastro-intestinal system	0.699	0.301
Y50 Central nervous system stimulants, not elsewhere classified	0.699	0.301
Y49 Psychotropic drugs, not elsewhere classified	0.699	0.301
Y48 Anaesthetics and therapeutic gases	0.699	0.301
Y47 Sedatives, hypnotics and antianxiety drugs	0.699	0.301
Y46 Antiepileptics and anti-Parkinsonism drugs	0.699	0.301
Y52.4 Angiotensin-converting-enzyme inhibitors	0.699	0.301
Y88 Sequelae of surgical and medical care as external cause	0.698	0.301
T79-T79 Certain early complications of trauma	0.698	0.302
M10 Gout	0.698	0.302
S46 Injury of muscle and tendon at shoulder and upper arm level	0.698	0.302
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.698	0.302
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.698	0.302
B65-B83 Helminthiases	0.697	0.302
M13.9 Arthritis, unspecified	0.697	0.303
B85-B89 Pediculosis, acariasis and other infestations	0.697	0.303
B50-B64 Protozoal diseases	0.697	0.303
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.697	0.303
A75-A79 Rickettsioses	0.697	0.303
A70-A74 Other diseases caused by chlamydiae	0.697	0.303
A65-A69 Other spirochaetal diseases	0.697	0.303
A20-A28 Certain zoonotic bacterial diseases	0.697	0.303
A15-A19 Tuberculosis	0.697	0.303
G82 Paraplegia and tetraplegia	0.697	0.303
M11 Other crystal arthropathies	0.697	0.303
S81 Open wound of lower leg	0.696	0.304
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.696	0.304
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.696	0.304
A49.0 Staphylococcal infection, unspecified	0.695	0.305
G57 Mononeuropathies of lower limb	0.694	0.306
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.693	0.307
Y41 Other systemic anti-infectives and antiparasitics	0.693	0.307
T66-T78 Other and unspecified effects of external causes	0.693	0.307
S19 Other and unspecified injuries of neck	0.692	0.308
M54.6 Pain in thoracic spine	0.692	0.308
M25.56 Pain in joint (Lower leg)	0.691	0.309
S41 Open wound of shoulder and upper arm	0.691	0.309
T36-T50 Poisoning by drugs, medicaments and biological substances	0.691	0.309
R87.7 Abnormal histological findings	0.690	0.310
S48 Traumatic amputation of shoulder and upper arm	0.690	0.310
S45 Injury of blood vessels at shoulder and upper arm level	0.690	0.310
S44 Injury of nerves at shoulder and upper arm level	0.690	0.310
S47 Crushing injury of shoulder and upper arm	0.690	0.310
Chapter II Neoplasms	0.690	0.310
D55-D59 Haemolytic anaemias	0.689	0.311
B15-B19 Viral hepatitis	0.688	0.312
M22 Disorders of patella	0.688	0.312
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.687	0.312
R95-R99 Ill-defined and unknown causes of mortality	0.687	0.313
S61.8 Open wound of other parts of wrist and hand	0.687	0.313
M51.3 Other specified intervertebral disk degeneration	0.684	0.316
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.684	0.316
M51.4 Schmorl's nodes	0.684	0.316
R94.3 Abnormal results of cardiovascular function studies	0.684	0.316
M54.4 Lumbago with sciatica	0.684	0.316
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.684	0.316
Y43.9 Primarily systemic agent, unspecified	0.683	0.317
Y43.8 Other primarily systemic agents, not elsewhere classified	0.683	0.317
Y43.6 Enzymes, not elsewhere classified	0.683	0.317
Y43.5 Acidifying and alkalising agents	0.683	0.317
Y43.4 Immunosuppressive agents	0.683	0.317
Y43.2 Antineoplastic natural products	0.683	0.317
R92 Abnormal findings on diagnostic imaging of breast	0.682	0.317
B20-B24 Human immunodeficiency virus [HIV] disease	0.682	0.318
M14 Arthropathies in other diseases classified elsewhere	0.682	0.318
Y60-Y69 Misadventures to patients during surgical and medical care	0.682	0.318
B44 Aspergillosis	0.680	0.320
G44 Other headache syndromes	0.680	0.320
A48 Other bacterial diseases, not elsewhere classified	0.679	0.321
A44 Bartonellosis	0.679	0.321
A43 Nocardiosis	0.679	0.321
A42 Actinomycosis	0.679	0.321
A39 Meningococcal infection	0.679	0.321
A37 Whooping cough	0.679	0.321
A36 Diphtheria	0.679	0.321
A32 Listeriosis	0.679	0.321
A31 Infection due to other mycobacteria	0.679	0.321
A30 Leprosy [Hansen's disease]	0.679	0.321
A38 Scarlet fever	0.679	0.321
A35 Other tetanus	0.679	0.321
A34 Obstetrical tetanus	0.679	0.321
A33 Tetanus neonatorum	0.679	0.321
S64.3 Injury of digital nerve of thumb	0.679	0.321
G41 Status epilepticus	0.678	0.321
S20 Superficial injury of thorax	0.678	0.322
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.678	0.322
T84.3 Mechanical complication of other bone devices, implants and grafts	0.678	0.322
G40.8 Other epilepsy	0.678	0.322
M54.5 Low back pain	0.677	0.322
M25.55 Pain in joint (Pelvic region and thigh)	0.677	0.323
S42.9 Fracture of shoulder girdle, part unspecified	0.677	0.323
S42.8 Fracture of other parts of shoulder and upper arm	0.677	0.323
S42.7 Multiple fractures of clavicle, scapula and humerus	0.677	0.323
S14 Injury of nerves and spinal cord at neck level	0.676	0.323
T21 Burn and corrosion of trunk	0.676	0.323
Y43.1 Antineoplastic antimetabolites	0.676	0.324
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.675	0.325
D52.9 Folate deficiency anaemia, unspecified	0.675	0.325
M90 Osteopathies in diseases classified elsewhere	0.674	0.326
R22.4 Localised swelling, mass and lump, lower limb	0.674	0.326
G90-G99 Other disorders of the nervous system	0.674	0.326
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.672	0.328
T81.9 Unspecified complication of procedure	0.672	0.328
T87.6 Other and unspecified complications of amputation stump	0.671	0.329
M34 Systemic sclerosis	0.671	0.329
T93.1 Sequelae of fracture of femur	0.671	0.329
G37 Other demyelinating diseases of central nervous system	0.671	0.329
S62 Fracture at wrist and hand level	0.670	0.329
S02 Fracture of skull and facial bones	0.670	0.330
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.670	0.330
M53 Other dorsopathies, not elsewhere classified	0.670	0.330
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.670	0.330
S70 Superficial injury of hip and thigh	0.669	0.330
R26 Abnormalities of gait and mobility	0.669	0.331
G51 Facial nerve disorders	0.668	0.332
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.667	0.333
Y89 Sequelae of other external causes	0.666	0.333
R93.6 Abnormal findings on diagnostic imaging of limbs	0.666	0.334
R22.2 Localised swelling, mass and lump, trunk	0.666	0.334
S89 Other and unspecified injuries of lower leg	0.664	0.335
G58 Other mononeuropathies	0.664	0.336
S22.0 Fracture of thoracic vertebra	0.664	0.336
A00-A09 Intestinal infectious diseases	0.664	0.336
M91-M94 Chondropathies	0.663	0.336
T93.2 Sequelae of other fractures of lower limb	0.663	0.337
R90 Abnormal findings on diagnostic imaging of central nervous system	0.662	0.338
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.662	0.338
M33 Dermatopolymyositis	0.662	0.338
M30 Polyarteritis nodosa and related conditions	0.662	0.338
A49.9 Bacterial infection, unspecified	0.661	0.339
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.661	0.339
S67.0 Crushing injury of thumb and other finger(s)	0.660	0.340
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.660	0.340
D74 Methaemoglobinaemia	0.660	0.340
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.660	0.340
D71 Functional disorders of polymorphonuclear neutrophils	0.660	0.340
S12.2 Fracture of other specified cervical vertebra	0.659	0.341
S22.2 Fracture of sternum	0.659	0.341
S79 Other and unspecified injuries of hip and thigh	0.659	0.341
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.659	0.341
R22.3 Localised swelling, mass and lump, upper limb	0.658	0.341
M89.8 Other specified disorders of bone	0.658	0.342
T90.8 Sequelae of other specified injuries of head	0.658	0.342
T90.3 Sequelae of injury of cranial nerves	0.658	0.342
T90.1 Sequelae of open wound of head	0.658	0.342
T90.0 Sequelae of superficial injury of head	0.658	0.342
S68 Traumatic amputation of wrist and hand	0.658	0.342
R87.6 Abnormal cytological findings	0.657	0.343
R84 Abnormal findings in specimens from respiratory organs and thorax	0.656	0.344
Chapter XV Pregnancy, childbirth and the puerperium	0.655	0.345
R86 Abnormal findings in specimens from male genital organs	0.654	0.346
M13.94 Arthritis, unspecified (Hand)	0.654	0.346
S60 Superficial injury of wrist and hand	0.653	0.347
S27.9 Injury of unspecified intrathoracic organ	0.653	0.347
S27.8 Injury of other specified intrathoracic organs	0.653	0.347
S27.7 Multiple injuries of intrathoracic organs	0.653	0.347
S27.6 Injury of pleura	0.653	0.347
S27.5 Injury of thoracic trachea	0.653	0.347
S27.4 Injury of bronchus	0.653	0.347
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.653	0.347
X60-X84 Intentional self-harm	0.653	0.347
M51.8 Other specified intervertebral disk disorders	0.652	0.348
S49 Other and unspecified injuries of shoulder and upper arm	0.652	0.348
B37.3 Candidiasis of vulva and vagina	0.652	0.348
M50.1 Cervical disk disorder with radiculopathy	0.652	0.348
D72 Other disorders of white blood cells	0.652	0.348
G06 Intracranial and intraspinal abscess and granuloma	0.652	0.348
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.652	0.348
M25.50 Pain in joint (Multiple sites)	0.651	0.348
M21 Other acquired deformities of limbs	0.651	0.349
M25.9 Joint disorder, unspecified	0.651	0.349
M25.2 Flail joint	0.651	0.349
M25.1 Fistula of joint	0.651	0.349
M25.0 Haemarthrosis	0.651	0.349
Y45.2 Propionic acid derivatives	0.651	0.349
B25-B34 Other viral diseases	0.651	0.349
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.651	0.349
A41.4 Septicaemia due to anaerobes	0.650	0.350
A41.3 Septicaemia due to Haemophilus influenzae	0.650	0.350
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.650	0.350
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.650	0.350
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.650	0.350
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.650	0.350
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.650	0.350
A49.8 Other bacterial infections of unspecified site	0.648	0.352
S86 Injury of muscle and tendon at lower leg level	0.647	0.352
B48 Other mycoses, not elsewhere classified	0.647	0.353
B47 Mycetoma	0.647	0.353
B46 Zygomycosis	0.647	0.353
B45 Cryptococcosis	0.647	0.353
B43 Chromomycosis and phaeomycotic abscess	0.647	0.353
B42 Sporotrichosis	0.647	0.353
B41 Paracoccidioidomycosis	0.647	0.353
B40 Blastomycosis	0.647	0.353
B39 Histoplasmosis	0.647	0.353
B38 Coccidioidomycosis	0.647	0.353
B36 Other superficial mycoses	0.647	0.353
B49 Unspecified mycosis	0.647	0.353
S61.7 Multiple open wounds of wrist and hand	0.646	0.354
W00-W19 Falls	0.645	0.355
G53 Cranial nerve disorders in diseases classified elsewhere	0.645	0.355
G52 Disorders of other cranial nerves	0.645	0.355
A80-A89 Viral infections of the central nervous system	0.644	0.355
M06 Other rheumatoid arthritis	0.644	0.356
W20-W49 Exposure to inanimate mechanical forces	0.644	0.356
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.644	0.356
S61.1 Open wound of finger(s) with damage to nail	0.643	0.356
S17 Crushing injury of neck	0.643	0.356
S15 Injury of blood vessels at neck level	0.643	0.356
S11 Open wound of neck	0.643	0.356
S10 Superficial injury of neck	0.643	0.356
S18 Traumatic amputation at neck level	0.643	0.356
S16 Injury of muscle and tendon at neck level	0.643	0.356
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.643	0.357
S42.10 Fracture of scapula (closed)	0.643	0.357
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.643	0.357
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.642	0.358
S29 Other and unspecified injuries of thorax	0.642	0.358
S42.31 Fracture of shaft of humerus (open)	0.641	0.358
S27.2 Traumatic heamopneumothorax	0.640	0.360
T23 Burn and corrosion of wrist and hand	0.640	0.360
C50-C50 Malignant neoplasm of breast	0.639	0.361
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.639	0.361
M12 Other specific arthropathies	0.638	0.362
M09 Juvenile arthritis in diseases classified elsewhere	0.638	0.362
M08 Juvenile arthritis	0.638	0.362
T87.4 Infection of amputation stump	0.638	0.362
G50 Disorders of trigeminal nerve	0.637	0.363
A41.8 Other specified septicaemia	0.637	0.363
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.637	0.363
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.637	0.363
R89 Abnormal findings in specimens from other organs, systems and tissues	0.636	0.364
R83 Abnormal findings in cerebrospinal fluid	0.636	0.364
T90.5 Sequelae of intracranial injury	0.636	0.364
Chapter IV Endocrine, nutritional and metabolic diseases	0.636	0.364
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.636	0.364
M07 Psoriatic and enteropathic arthropathies	0.635	0.364
G72 Other myopathies	0.635	0.365
S88 Traumatic amputation of lower leg	0.634	0.366
S87 Crushing injury of lower leg	0.634	0.366
S85 Injury of blood vessels at lower leg level	0.634	0.366
S84 Injury of nerves at lower leg level	0.634	0.366
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.634	0.366
M75 Shoulder lesions	0.633	0.367
A50-A64 Infections with a predominantly sexual mode of transmission	0.632	0.367
D61 Other aplastic anaemias	0.632	0.368
R20.2 Paraesthesia of skin	0.631	0.369
R23.3 Spontaneous ecchymoses	0.630	0.370
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.630	0.370
L80-L99 Other disorders of the skin and subcutaneous tissue	0.629	0.371
G59.0 Diabetic mononeuropathy	0.629	0.371

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations