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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35620136
log Bayes Factor = 15.1317
Chromosome 5   position 140,530,718  (GRCh37) Explore rs35620136 on Ensembl!
Variant rs35620136 is part of Cluster X0082

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
R50-R69 General symptoms and signs
1.000 0.000 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
R59 Enlarged lymph nodes
0.998 0.002 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.998 0.002 0.000
Z51 Other medical care
0.998 0.002 0.000
C15-C26 Malignant neoplasms of digestive organs
0.996 0.004 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.994 0.006 0.000
Chapter V Mental and behavioural disorders
0.994 0.006 0.000
Z51.5 Palliative care
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
C78.7 Secondary malignant neoplasm of liver
0.983 0.017 0.000
R59.0 Localised enlarged lymph nodes
0.982 0.018 0.000
C79 Secondary malignant neoplasm of other sites
0.978 0.022 0.000
Chapter XI Diseases of the digestive system
0.977 0.023 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.974 0.026 0.000
C18 Malignant neoplasm of colon
0.971 0.029 0.000
K50-K52 Noninfective enteritis and colitis
0.967 0.033 0.000
R53 Malaise and fatigue
0.966 0.034 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.958 0.042 0.000
Y43 Primarily systemic agents
0.957 0.043 0.000
Chapter X Diseases of the respiratory system
0.953 0.047 0.000
R59.1 Generalised enlarged lymph nodes
0.953 0.047 0.000
R47-R49 Symptoms and signs involving speech and voice
0.953 0.047 0.000
C78.0 Secondary malignant neoplasm of lung
0.952 0.048 0.000
K51 Ulcerative colitis
0.952 0.048 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.947 0.053 0.000
E10-E14 Diabetes mellitus
0.945 0.055 0.000
Y43.3 Other antineoplastic drugs
0.940 0.060 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.939 0.061 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.936 0.064 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.936 0.064 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.929 0.071 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.928 0.072 0.000
C77.2 Intra-abdominal lymph nodes
0.928 0.072 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.927 0.073 0.000
C15 Malignant neoplasm of oesophagus
0.927 0.073 0.000
Z51.0 Radiotherapy session
0.926 0.074 0.000
K65-K67 Diseases of peritoneum
0.926 0.074 0.000
M50-M54 Other dorsopathies
0.923 0.077 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.922 0.078 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.919 0.081 0.000
F10.1 Harmful use
0.911 0.089 0.000
K51.9 Ulcerative colitis, unspecified
0.911 0.089 0.000
R49 Voice disturbances
0.911 0.089 0.000
Z50 Care involving use of rehabilitation procedures
0.911 0.089 0.000
R69 Unknown and unspecified causes of morbidity
0.909 0.091 0.000
E10 Insulin-dependent diabetes mellitus
0.909 0.091 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.906 0.094 0.000
C20 Malignant neoplasm of rectum
0.895 0.105 0.000
M51 Other intervertebral disk disorders
0.895 0.105 0.000
Z51.8 Other specified medical care
0.891 0.109 0.000
R56 Convulsions, not elsewhere classified
0.888 0.112 0.000
E14 Unspecified diabetes mellitus
0.888 0.112 0.000
R50 Fever of unknown origin
0.886 0.114 0.000
Z51.3 Blood transfusion without reported diagnosis
0.886 0.114 0.000
Z51.1 Chemotherapy session for neoplasm
0.883 0.117 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.880 0.120 0.000
C77.0 Lymph nodes of head, face and neck
0.878 0.122 0.000
R59.9 Enlarged lymph nodes, unspecified
0.877 0.123 0.000
Chapter VII Diseases of the eye and adnexa
0.872 0.128 0.000
M54 Dorsalgia
0.871 0.129 0.000
C51-C58 Malignant neoplasms of female genital organs
0.870 0.130 0.000
M51.2 Other specified intervertebral disk displacement
0.867 0.133 0.000
R49.0 Dysphonia
0.865 0.135 0.000
Z43 Attention to artificial openings
0.863 0.137 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.863 0.137 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.862 0.138 0.000
C77.3 Axillary and upper limb lymph nodes
0.862 0.138 0.000
J60-J70 Lung diseases due to external agents
0.856 0.144 0.000
C18.6 Descending colon
0.852 0.148 0.000
K66 Other disorders of peritoneum
0.851 0.149 0.000
E14.9 Without complications
0.851 0.149 0.000
C50-C50 Malignant neoplasm of breast
0.851 0.149 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.850 0.150 0.000
C77.5 Intrapelvic lymph nodes
0.849 0.151 0.000
Z29 Need for other prophylactic measures
0.847 0.153 0.000
M65-M68 Disorders of synovium and tendon
0.844 0.156 0.000
Z50.1 Other physical therapy
0.843 0.157 0.000
C77.1 Intrathoracic lymph nodes
0.837 0.163 0.000
K50 Crohn's disease [regional enteritis]
0.837 0.163 0.000
M54.9 Dorsalgia, unspecified
0.834 0.166 0.000
C18.0 Caecum
0.834 0.166 0.000
D10-D36 Benign neoplasms
0.831 0.169 0.000
C78.2 Secondary malignant neoplasm of pleura
0.828 0.172 0.000
D70 Agranulocytosis
0.827 0.173 0.000
K90-K93 Other diseases of the digestive system
0.826 0.174 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.818 0.182 0.000
Z45 Adjustment and management of implanted device
0.818 0.182 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.818 0.182 0.000
C15.9 Oesophagus, unspecified
0.813 0.187 0.000
F60-F69 Disorders of adult personality and behaviour
0.813 0.187 0.000
C18.9 Colon, unspecified
0.811 0.189 0.000
F00 Dementia in Alzheimer's disease
0.810 0.190 0.000
J40-J47 Chronic lower respiratory diseases
0.809 0.191 0.000
R56.8 Other and unspecified convulsions
0.809 0.191 0.000
R26 Abnormalities of gait and mobility
0.807 0.193 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.806 0.194 0.000
D60-D64 Aplastic and other anaemias
0.806 0.194 0.000
J95-J99 Other diseases of the respiratory system
0.799 0.201 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.796 0.204 0.000
K65 Peritonitis
0.796 0.204 0.000
K51.2 Ulcerative (chronic) proctitis
0.795 0.205 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.793 0.207 0.000
D18 Haemangioma and lymphangioma, any site
0.792 0.208 0.000
E10.9 Without complications
0.792 0.208 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.790 0.210 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.789 0.211 0.000
M20-M25 Other joint disorders
0.789 0.211 0.000
K66.0 Peritoneal adhesions
0.789 0.211 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.789 0.211 0.000
J69 Pneumonitis due to solids and liquids
0.788 0.212 0.000
J20-J22 Other acute lower respiratory infections
0.787 0.213 0.000
R50.9 Fever, unspecified
0.787 0.213 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.783 0.217 0.000
W20-W49 Exposure to inanimate mechanical forces
0.783 0.217 0.000
E13 Other specified diabetes mellitus
0.783 0.217 0.000
H53-H54 Visual disturbances and blindness
0.781 0.219 0.000
M25 Other joint disorders, not elsewhere classified
0.779 0.221 0.000
M65 Synovitis and tenosynovitis
0.779 0.221 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.777 0.223 0.000
E20-E35 Disorders of other endocrine glands
0.776 0.224 0.000
C15.5 Lower third of oesophagus
0.775 0.225 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.775 0.225 0.000
Y52 Agents primarily affecting the cardiovascular system
0.772 0.228 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.771 0.229 0.000
Z43.2 Attention to ileostomy
0.771 0.229 0.000
R52 Pain, not elsewhere classified
0.771 0.229 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.770 0.230 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.770 0.230 0.000
K51.4 Pseudopolyposis of colon
0.770 0.230 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.767 0.233 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.766 0.233 0.000
Chapter XXII Codes for special purposes
0.766 0.234 0.000
C56 Malignant neoplasm of ovary
0.766 0.234 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.765 0.235 0.000
D18.0 Haemangioma, any site
0.765 0.235 0.000
Y43.4 Immunosuppressive agents
0.764 0.236 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.761 0.239 0.000
Z22 Carrier of infectious disease
0.761 0.239 0.000
E10.1 With ketoacidosis
0.760 0.240 0.000
K70-K77 Diseases of liver
0.760 0.240 0.000
C18.4 Transverse colon
0.759 0.241 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.758 0.242 0.000
M25.5 Pain in joint
0.758 0.242 0.000
C18.7 Sigmoid colon
0.756 0.244 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.755 0.245 0.000
F10.9 Unspecified mental and behavioural disorder
0.755 0.245 0.000
K50.0 Crohn's disease of small intestine
0.752 0.248 0.000
E65-E68 Obesity and other hyperalimentation
0.750 0.250 0.000
C77.9 Lymph node, unspecified
0.747 0.253 0.000
R68 Other general symptoms and signs
0.745 0.255 0.000
C50 Malignant neoplasm of breast
0.744 0.256 0.000
R49.8 Other and unspecified voice disturbances
0.744 0.256 0.000
Z49 Care involving dialysis
0.743 0.257 0.000
M86-M90 Other osteopathies
0.742 0.258 0.000
D12.3 Transverse colon
0.742 0.258 0.000
Z33 Pregnant state, incidental
0.741 0.259 0.000
K51.5 Mucosal proctocolitis
0.740 0.260 0.000
J69.0 Pneumonitis due to food and vomit
0.739 0.261 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.738 0.262 0.000
J44 Other chronic obstructive pulmonary disease
0.737 0.263 0.000
R47 Speech disturbances, not elsewhere classified
0.736 0.264 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.736 0.264 0.000
C18.3 Hepatic flexure
0.735 0.265 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.733 0.267 0.000
Z29.8 Other specified prophylactic measures
0.733 0.267 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.732 0.268 0.000
J00-J06 Acute upper respiratory infections
0.732 0.268 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.731 0.269 0.000
X60-X84 Intentional self-harm
0.730 0.270 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.730 0.270 0.000
Y40 Systemic antibiotics
0.728 0.272 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.728 0.272 0.000
C15.4 Middle third of oesophagus
0.728 0.272 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.728 0.272 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.727 0.273 0.000
M51.8 Other specified intervertebral disk disorders
0.726 0.274 0.000
Z42 Follow-up care involving plastic surgery
0.726 0.274 0.000
F30-F39 Mood [affective] disorders
0.725 0.275 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.724 0.276 0.000
K40-K46 Hernia
0.724 0.276 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.723 0.277 0.000
C79.2 Secondary malignant neoplasm of skin
0.723 0.277 0.000
K11 Diseases of salivary glands
0.722 0.278 0.000
Z54 Convalescence
0.719 0.281 0.000
Z52 Donors of organs and tissues
0.719 0.281 0.000
W00-W19 Falls
0.719 0.281 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.718 0.282 0.000
E10.2 With renal complications
0.718 0.282 0.000
D64 Other anaemias
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.717 0.283 0.000
R62 Lack of expected normal physiological development
0.717 0.283 0.000
R57 Shock, not elsewhere classified
0.717 0.283 0.000
R64 Cachexia
0.717 0.283 0.000
R58 Haemorrhage, not elsewhere classified
0.717 0.283 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.717 0.283 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.717 0.283 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.283 0.000
E40-E46 Malnutrition
0.716 0.283 0.000
E10.5 With peripheral circulatory complications
0.716 0.284 0.000
Z44 Fitting and adjustment of external prosthetic device
0.715 0.284 0.000
Z51.9 Medical care, unspecified
0.715 0.285 0.000
Z51.6 Desensitisation to allergens
0.715 0.285 0.000
K13 Other diseases of lip and oral mucosa
0.715 0.285 0.000
D50-D53 Nutritional anaemias
0.715 0.285 0.000
Z50.0 Cardiac rehabilitation
0.715 0.285 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.714 0.286 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.714 0.286 0.000
C21 Malignant neoplasm of anus and anal canal
0.714 0.286 0.000
C17 Malignant neoplasm of small intestine
0.714 0.286 0.000
C23 Malignant neoplasm of gallbladder
0.714 0.286 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.713 0.287 0.000
V20-V29 Motorcycle rider injured in transport accident
0.713 0.287 0.000
F99-F99 Unspecified mental disorder
0.712 0.288 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.288 0.000
F80-F89 Disorders of psychological development
0.712 0.288 0.000
F70-F79 Mental retardation
0.712 0.288 0.000
M65.3 Trigger finger
0.712 0.288 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.711 0.289 0.000
K92 Other diseases of digestive system
0.710 0.290 0.000
K52 Other non-infective gastro-enteritis and colitis
0.709 0.291 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.709 0.291 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.708 0.292 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.708 0.292 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.708 0.292 0.000
X50-X57 Overexertion, travel and privation
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
W50-W64 Exposure to animate mechanical forces
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V80-V89 Other land transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V40-V49 Car occupant injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.292 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.707 0.293 0.000
Z29.2 Other prophylactic chemotherapy
0.707 0.293 0.000
C18.5 Splenic flexure
0.706 0.294 0.000
F03 Unspecified dementia
0.706 0.294 0.000
C77.8 Lymph nodes of multiple regions
0.705 0.295 0.000
Z45.1 Adjustment and management of infusion pump
0.705 0.295 0.000
O00-O08 Pregnancy with abortive outcome
0.703 0.296 0.000
O42 Premature rupture of membranes
0.702 0.297 0.000
K04 Diseases of pulp and periapical tissues
0.702 0.298 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.702 0.298 0.000
C79.6 Secondary malignant neoplasm of ovary
0.701 0.299 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.701 0.299 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.701 0.299 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.701 0.299 0.000
F01 Vascular dementia
0.700 0.300 0.000
J40 Bronchitis, not specified as acute or chronic
0.700 0.300 0.000
O36 Maternal care for other known or suspected foetal problems
0.700 0.300 0.000
C64-C68 Malignant neoplasms of urinary tract
0.699 0.301 0.000
E10.4 With neurological complications
0.699 0.301 0.000
Y59 Other and unspecified vaccines and biological substances
0.698 0.302 0.000
Y58 Bacterial vaccines
0.698 0.302 0.000
Y57 Other and unspecified drugs and medicaments
0.698 0.302 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.698 0.302 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.698 0.302 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.698 0.302 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.698 0.302 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.698 0.302 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.698 0.302 0.000
Y48 Anaesthetics and therapeutic gases
0.698 0.302 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.698 0.302 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.698 0.302 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.698 0.302 0.000
E10.3 With ophthalmic complications
0.698 0.302 0.000
C18.8 Overlapping lesion of colon
0.696 0.304 0.000
C18.1 Appendix
0.696 0.304 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.696 0.304 0.000
J90-J94 Other diseases of pleura
0.696 0.304 0.000
Z41 Procedures for purposes other than remedying health state
0.695 0.305 0.000
D16 Benign neoplasm of bone and articular cartilage
0.695 0.305 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.694 0.306 0.000
C25 Malignant neoplasm of pancreas
0.693 0.307 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.692 0.308 0.000
K65.9 Peritonitis, unspecified
0.691 0.309 0.000
M25.8 Other specified joint disorders
0.691 0.309 0.000
H53 Visual disturbances
0.690 0.310 0.000
C80 Malignant neoplasm without specification of site
0.690 0.310 0.000
C50.4 Upper-outer quadrant of breast
0.690 0.310 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.689 0.311 0.000
K12 Stomatitis and related lesions
0.689 0.311 0.000
R54 Senility
0.688 0.312 0.000
C18.2 Ascending colon
0.688 0.312 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.687 0.313 0.000
Y43.9 Primarily systemic agent, unspecified
0.686 0.314 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.686 0.314 0.000
Y43.6 Enzymes, not elsewhere classified
0.686 0.314 0.000
Y43.5 Acidifying and alkalising agents
0.686 0.314 0.000
Y43.2 Antineoplastic natural products
0.686 0.314 0.000
Y43.1 Antineoplastic antimetabolites
0.686 0.314 0.000
Y43.0 Antiallergic and antiemetic drugs
0.686 0.314 0.000
V10-V19 Pedal cyclist injured in transport accident
0.686 0.314 0.000
R52.9 Pain, unspecified
0.684 0.316 0.000
F60 Specific personality disorders
0.683 0.317 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.683 0.317 0.000
D26 Other benign neoplasms of uterus
0.683 0.317 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.682 0.318 0.000
D55-D59 Haemolytic anaemias
0.679 0.321 0.000
H55-H59 Other disorders of eye and adnexa
0.679 0.321 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.678 0.322 0.000
E12 Malnutrition-related diabetes mellitus
0.677 0.323 0.000
F43 Reaction to severe stress, and adjustment disorders
0.677 0.323 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.675 0.325 0.000
K51.8 Other ulcerative colitis
0.675 0.325 0.000
O20 Haemorrhage in early pregnancy
0.675 0.325 0.000
O24 Diabetes mellitus in pregnancy
0.674 0.326 0.000
R50.0 Fever with chills
0.673 0.326 0.000
E23 Hypofunction and other disorders of pituitary gland
0.673 0.327 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.673 0.327 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.673 0.327 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.673 0.327 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.673 0.327 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.673 0.327 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.673 0.327 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.673 0.327 0.000
F11 Mental and behavioural disorders due to use of opioids
0.673 0.327 0.000
M91-M94 Chondropathies
0.671 0.329 0.000
M60-M63 Disorders of muscles
0.671 0.329 0.000
M00-M03 Infectious arthropathies
0.671 0.329 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.671 0.329 0.000
K70 Alcoholic liver disease
0.670 0.330 0.000
D12.6 Colon, unspecified
0.669 0.331 0.000
M54.3 Sciatica
0.667 0.333 0.000
E13.9 Without complications
0.667 0.333 0.000
K43 Ventral hernia
0.666 0.334 0.000
Z50.5 Speech therapy
0.666 0.334 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.665 0.335 0.000
Z28 Immunisation not carried out
0.665 0.335 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.665 0.335 0.000
Z26 Need for immunisation against other single infectious diseases
0.665 0.335 0.000
Z25 Need for immunisation against other single viral diseases
0.665 0.335 0.000
Z24 Need for immunisation against certain single viral diseases
0.665 0.335 0.000
Z23 Need for immunisation against single bacterial diseases
0.665 0.335 0.000
Z20 Contact with and exposure to communicable diseases
0.665 0.335 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.665 0.335 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.665 0.335 0.000
C15.8 Overlapping lesion of oesophagus
0.664 0.336 0.000
C15.3 Upper third of oesophagus
0.664 0.336 0.000
C15.2 Abdominal part of oesophagus
0.664 0.336 0.000
C15.1 Thoracic part of oesophagus
0.664 0.336 0.000
C15.0 Cervical part of oesophagus
0.664 0.336 0.000
M65.34 Trigger finger-Hand
0.664 0.336 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.664 0.336 0.000
R29.6 Tendency to fall, not elsewhere classified
0.663 0.337 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.663 0.337 0.000
M54.2 Cervicalgia
0.661 0.339 0.000
F10.8 Other mental and behavioural disorders
0.661 0.339 0.000
F10.7 Residual and late-onset psychotic disorder
0.661 0.339 0.000
F10.6 Amnesic syndrome
0.661 0.339 0.000
F10.5 Psychotic disorder
0.661 0.339 0.000
F10.4 Withdrawal state with delirium
0.661 0.339 0.000
J22 Unspecified acute lower respiratory infection
0.661 0.339 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.660 0.340 0.000
R90.0 Intracranial space-occupying lesion
0.660 0.340 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.659 0.341 0.000
F02 Dementia in other diseases classified elsewhere
0.659 0.341 0.000
F09 Unspecified organic or symptomatic mental disorder
0.659 0.341 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.659 0.341 0.000
J98 Other respiratory disorders
0.657 0.343 0.000
Z40 Prophylactic surgery
0.657 0.343 0.000
R25 Abnormal involuntary movements
0.657 0.343 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.656 0.344 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.655 0.344 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.654 0.346 0.000
D64.9 Anaemia, unspecified
0.654 0.346 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.653 0.347 0.000
R49.2 Hypernasality and hyponasality
0.653 0.347 0.000
R49.1 Aphonia
0.653 0.347 0.000
Z50.6 Orthoptic training
0.653 0.347 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.653 0.347 0.000
Z50.3 Drug rehabilitation
0.653 0.347 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.653 0.347 0.000
O42.9 Premature rupture of membranes, unspecified
0.653 0.347 0.000
M24 Other specific joint derangements
0.652 0.347 0.000
M53 Other dorsopathies, not elsewhere classified
0.652 0.348 0.000
E10.8 With unspecified complications
0.652 0.348 0.000
E10.7 With multiple complications
0.652 0.348 0.000
E10.6 With other specified complications
0.652 0.348 0.000
E10.0 With coma
0.652 0.348 0.000
F10.3 Withdrawal state
0.651 0.349 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.650 0.350 0.000
H50 Other strabismus
0.650 0.350 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.649 0.351 0.000
Y95 Nosocomial condition
0.648 0.352 0.000
K92.1 Melaena
0.648 0.352 0.000
H10-H13 Disorders of conjunctiva
0.646 0.354 0.000
K66.8 Other specified disorders of peritoneum
0.646 0.354 0.000
R60 Oedema, not elsewhere classified
0.645 0.354 0.000
R50.8 Other specified fever
0.644 0.355 0.000
M54.4 Lumbago with sciatica
0.644 0.356 0.000
C24.0 Extrahepatic bile duct
0.643 0.357 0.000
M54.1 Radiculopathy
0.643 0.357 0.000
Z22.3 Carrier of other specified bacterial diseases
0.642 0.358 0.000
M51.3 Other specified intervertebral disk degeneration
0.641 0.358 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.641 0.358 0.000
M51.9 Intervertebral disk disorder, unspecified
0.641 0.358 0.000
M51.4 Schmorl's nodes
0.641 0.358 0.000
Z32 Pregnancy examination and test
0.641 0.359 0.000
Chapter I Certain infectious and parasitic diseases
0.641 0.359 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.639 0.361 0.000
C50.9 Breast, unspecified
0.639 0.361 0.000
C77.4 Inguinal and lower limb lymph nodes
0.638 0.361 0.000
Z29.1 Prophylactic immunotherapy
0.637 0.362 0.000
R56.0 Febrile convulsions
0.637 0.363 0.000
E14.8 With unspecified complications
0.637 0.363 0.000
E14.7 With multiple complications
0.637 0.363 0.000
E14.6 With other specified complications
0.637 0.363 0.000
E14.5 With peripheral circulatory complications
0.637 0.363 0.000
E14.4 With neurological complications
0.637 0.363 0.000
E14.2 Withrenal complications
0.637 0.363 0.000
E14.1 With ketoacidosis
0.637 0.363 0.000
E14.0 With coma
0.637 0.363 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.635 0.364 0.000
F10.2 Dependence syndrome
0.635 0.365 0.000
R50.2 Drug-induced fever
0.635 0.365 0.000
R50.1 Persistent fever
0.635 0.365 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.635 0.365 0.000
D80-D89 Certain disorders involving the immune mechanism
0.634 0.366 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.633 0.367 0.000
Y44 Agents primarily affecting blood constituents
0.632 0.368 0.000
F42 Obsessive-compulsive disorder
0.632 0.368 0.000
O85-O92 Complications predominantly related to the puerperium
0.631 0.369 0.000
K13.0 Diseases of lips
0.630 0.370 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.630 0.370 0.000
M25.57 Pain in joint (Ankle and foot)
0.628 0.372 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.628 0.372 0.000
Z50.2 Alcohol rehabilitation
0.627 0.372 0.000
D72 Other disorders of white blood cells
0.627 0.372 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.627 0.372 0.000
C71 Malignant neoplasm of brain
0.627 0.373 0.000
H40-H42 Glaucoma
0.627 0.373 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.625 0.375 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.625 0.375 0.000
M54.8 Other dorsalgia
0.625 0.375 0.000
M54.6 Pain in thoracic spine
0.625 0.375 0.000
M54.0 Panniculitis affecting regions of neck and back
0.625 0.375 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.624 0.376 0.000
C51 Malignant neoplasm of vulva
0.624 0.376 0.000
C58 Malignant neoplasm of placenta
0.624 0.376 0.000
C52 Malignant neoplasm of vagina
0.624 0.376 0.000
Z43.3 Attention to colostomy
0.623 0.377 0.000
D68 Other coagulation defects
0.622 0.378 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.622 0.378 0.000
Y42.7 Androgens and anabolic congeners
0.622 0.378 0.000
E27 Other disorders of adrenal gland
0.621 0.378 0.000
H54 Blindness and low vision
0.621 0.378 0.000
D11 Benign neoplasm of major salivary glands
0.621 0.379 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.620 0.379 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.621 0.379 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.620 0.380 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.620 0.380 0.000
W29 Contact with other powered hand tools and household machinery
0.619 0.381 0.000
Z43.9 Attention to unspecified artificial opening
0.619 0.381 0.000
Z43.8 Attention to other artificial openings
0.619 0.381 0.000
Z43.7 Attention to artificial vagina
0.619 0.381 0.000
Z43.5 Attention to cyctostomy
0.619 0.381 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.619 0.381 0.000
Z43.1 Attention to gastrostomy
0.619 0.381 0.000
Z43.0 Attention to tracheostomy
0.619 0.381 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.619 0.381 0.000
Q60-Q64 Congenital malformations of the urinary system
0.618 0.382 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.618 0.382 0.000
D74 Methaemoglobinaemia
0.618 0.382 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.618 0.382 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.618 0.382 0.000
O03 Spontaneous abortion
0.618 0.382 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.617 0.383 0.000
Z36 Antenatal screening
0.616 0.383 0.000
R61 Hyperhidrosis
0.616 0.384 0.000
M25.52 Pain in joint (Upper arm)
0.616 0.384 0.000
J30-J39 Other diseases of upper respiratory tract
0.615 0.385 0.000
C45 Mesothelioma
0.614 0.386 0.000
J70 Respiratory conditions due to other external agents
0.614 0.386 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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