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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35661976
log Bayes Factor = 15.2186
Chromosome 5   position 1,243,699  (GRCh37) Explore rs35661976 on Ensembl!
Variant rs35661976 is part of Cluster X0167

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z85 Personal history of malignant neoplasm
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.998 0.002 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.997 0.003 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.997 0.003 0.000
R50-R69 General symptoms and signs
0.996 0.004 0.000
D60-D64 Aplastic and other anaemias
0.995 0.005 0.000
C15-C26 Malignant neoplasms of digestive organs
0.995 0.005 0.000
Z90.1 Acquired absence of breast(s)
0.994 0.006 0.000
D64 Other anaemias
0.994 0.006 0.000
D64.9 Anaemia, unspecified
0.993 0.007 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.990 0.010 0.000
C78.0 Secondary malignant neoplasm of lung
0.989 0.011 0.000
Z51 Other medical care
0.988 0.012 0.000
C18 Malignant neoplasm of colon
0.986 0.014 0.000
Z51.5 Palliative care
0.983 0.017 0.000
I25.2 Old myocardial infarction
0.979 0.021 0.000
I25 Chronic ischaemic heart disease
0.978 0.022 0.000
R51 Headache
0.977 0.023 0.000
R50 Fever of unknown origin
0.976 0.024 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.972 0.028 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.971 0.029 0.000
C78.7 Secondary malignant neoplasm of liver
0.967 0.033 0.000
R50.9 Fever, unspecified
0.966 0.034 0.000
I20-I25 Ischaemic heart diseases
0.955 0.045 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.952 0.048 0.000
C50-C50 Malignant neoplasm of breast
0.950 0.050 0.000
D00-D09 In situ neoplasms
0.949 0.051 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.947 0.053 0.000
Chapter IX Diseases of the circulatory system
0.943 0.057 0.000
R21 Rash and other nonspecific skin eruption
0.940 0.060 0.000
Z51.0 Radiotherapy session
0.939 0.061 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.935 0.065 0.000
D10-D36 Benign neoplasms
0.934 0.066 0.000
Z42 Follow-up care involving plastic surgery
0.933 0.067 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.932 0.068 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.931 0.069 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.929 0.071 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.924 0.076 0.000
Z90.2 Acquired absence of lung [part of]
0.922 0.078 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.918 0.082 0.000
C50 Malignant neoplasm of breast
0.915 0.085 0.000
C34 Malignant neoplasm of bronchus and lung
0.913 0.087 0.000
C78.2 Secondary malignant neoplasm of pleura
0.909 0.091 0.000
R69 Unknown and unspecified causes of morbidity
0.907 0.093 0.000
C18.9 Colon, unspecified
0.894 0.106 0.000
C80 Malignant neoplasm without specification of site
0.888 0.112 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.886 0.114 0.000
R63 Symptoms and signs concerning food and fluid intake
0.880 0.120 0.000
Chapter VIII Diseases of the ear and mastoid process
0.877 0.123 0.000
C50.9 Breast, unspecified
0.870 0.130 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.870 0.130 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.869 0.131 0.000
C64-C68 Malignant neoplasms of urinary tract
0.867 0.133 0.000
D05 Carcinoma in situ of breast
0.864 0.136 0.000
D12.4 Descending colon
0.858 0.142 0.000
D50-D53 Nutritional anaemias
0.854 0.146 0.000
C18.7 Sigmoid colon
0.851 0.149 0.000
C18.0 Caecum
0.842 0.158 0.000
C18.1 Appendix
0.842 0.158 0.000
L50-L54 Urticaria and erythema
0.841 0.159 0.000
D12.0 Caecum
0.841 0.159 0.000
Z92 Personal history of medical treatment
0.841 0.159 0.000
I20 Angina pectoris
0.840 0.160 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.839 0.161 0.000
L40-L45 Papulosquamous disorders
0.838 0.162 0.000
C18.4 Transverse colon
0.836 0.164 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.834 0.166 0.000
Chapter XX External causes of morbidity and mortality
0.834 0.166 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.830 0.170 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.828 0.172 0.000
C23 Malignant neoplasm of gallbladder
0.824 0.176 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.824 0.176 0.000
C34.1 Upper lobe, bronchus or lung
0.820 0.180 0.000
D12.5 Sigmoid colon
0.815 0.185 0.000
Z86 Personal history of certain other diseases
0.815 0.185 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.814 0.186 0.000
D23 Other benign neoplasms of skin
0.812 0.188 0.000
D12.6 Colon, unspecified
0.810 0.190 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.804 0.195 0.000
Z86.0 Personal history of other neoplasms
0.804 0.196 0.000
Chapter X Diseases of the respiratory system
0.803 0.197 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.800 0.200 0.000
Z98 Other postsurgical states
0.799 0.201 0.000
C34.3 Lower lobe, bronchus or lung
0.796 0.204 0.000
I20.0 Unstable angina
0.795 0.205 0.000
D12.8 Rectum
0.791 0.209 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.790 0.210 0.000
Z51.3 Blood transfusion without reported diagnosis
0.789 0.211 0.000
Z51.1 Chemotherapy session for neoplasm
0.788 0.212 0.000
R60 Oedema, not elsewhere classified
0.786 0.214 0.000
C25 Malignant neoplasm of pancreas
0.782 0.218 0.000
Chapter I Certain infectious and parasitic diseases
0.782 0.218 0.000
C51-C58 Malignant neoplasms of female genital organs
0.782 0.218 0.000
C50.4 Upper-outer quadrant of breast
0.778 0.222 0.000
C20 Malignant neoplasm of rectum
0.776 0.224 0.000
Z92.3 Personal history of irradiation
0.775 0.225 0.000
Z93 Artificial opening status
0.773 0.227 0.000
I22 Subsequent myocardial infarction
0.773 0.227 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.772 0.228 0.000
Chapter VI Diseases of the nervous system
0.772 0.228 0.000
R58 Haemorrhage, not elsewhere classified
0.769 0.231 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.769 0.231 0.000
D04 Carcinoma in situ of skin
0.768 0.231 0.000
I25.3 Aneurysm of heart
0.768 0.232 0.000
D51 Vitamin B12 deficiency anaemia
0.766 0.234 0.000
C77.1 Intrathoracic lymph nodes
0.764 0.235 0.000
Z90.8 Acquired absence of other organs
0.764 0.236 0.000
D03 Melanoma in situ
0.764 0.236 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.763 0.237 0.000
D61 Other aplastic anaemias
0.760 0.240 0.000
L40 Psoriasis
0.760 0.240 0.000
J00-J06 Acute upper respiratory infections
0.758 0.242 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.754 0.246 0.000
R63.0 Anorexia
0.751 0.249 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.751 0.249 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.751 0.249 0.000
C77.9 Lymph node, unspecified
0.748 0.252 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.748 0.252 0.000
C18.6 Descending colon
0.746 0.254 0.000
C77.3 Axillary and upper limb lymph nodes
0.745 0.255 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.744 0.256 0.000
Z54 Convalescence
0.743 0.256 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.743 0.257 0.000
C34.9 Bronchus or lung, unspecified
0.743 0.257 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.743 0.257 0.000
C50.1 Central portion of breast
0.743 0.257 0.000
D68 Other coagulation defects
0.743 0.257 0.000
R20 Disturbances of skin sensation
0.742 0.258 0.000
S20-S29 Injuries to the thorax
0.742 0.258 0.000
Z49 Care involving dialysis
0.741 0.259 0.000
D05.1 Intraductal carcinoma in situ
0.741 0.259 0.000
D21.2 Connective and other soft tissue of lower limb, including hip
0.740 0.260 0.000
D27 Benign neoplasm of ovary
0.739 0.261 0.000
C77.2 Intra-abdominal lymph nodes
0.738 0.262 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.738 0.262 0.000
C15 Malignant neoplasm of oesophagus
0.735 0.265 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.735 0.265 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.734 0.266 0.000
D52 Folate deficiency anaemia
0.732 0.268 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.732 0.268 0.000
Z98.0 Intestinal bypass and anastomosis status
0.731 0.269 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.731 0.269 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.729 0.270 0.000
D11 Benign neoplasm of major salivary glands
0.729 0.271 0.000
D37.4 Colon
0.728 0.272 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.726 0.274 0.000
Z90.5 Acquired absence of kidney
0.724 0.276 0.000
D37.9 Digestive organ, unspecified
0.722 0.278 0.000
Z48 Other surgical follow-up care
0.722 0.278 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.722 0.278 0.000
D30 Benign neoplasm of urinary organs
0.721 0.279 0.000
D12.2 Ascending colon
0.721 0.279 0.000
C50.3 Lower-inner quadrant of breast
0.721 0.279 0.000
Chapter XXII Codes for special purposes
0.720 0.280 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.719 0.281 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.719 0.281 0.000
Z97 Presence of other devices
0.719 0.281 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.717 0.283 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.717 0.283 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.717 0.283 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.717 0.283 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.717 0.283 0.000
D55-D59 Haemolytic anaemias
0.715 0.284 0.000
C32 Malignant neoplasm of larynx
0.714 0.286 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.714 0.286 0.000
R62 Lack of expected normal physiological development
0.714 0.286 0.000
R64 Cachexia
0.714 0.286 0.000
H60-H62 Diseases of external ear
0.714 0.286 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.714 0.286 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.713 0.287 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.713 0.287 0.000
C21 Malignant neoplasm of anus and anal canal
0.713 0.287 0.000
C17 Malignant neoplasm of small intestine
0.713 0.287 0.000
H65-H75 Diseases of middle ear and mastoid
0.713 0.287 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.713 0.287 0.000
D64.8 Other specified anaemias
0.712 0.287 0.000
D64.4 Congenital dyserythropoietic anaemia
0.712 0.287 0.000
D64.3 Other sideroblastic anaemias
0.712 0.287 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.712 0.287 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.712 0.287 0.000
D64.0 Hereditary sideroblastic anaemia
0.712 0.287 0.000
D23.4 Skin of scalp and neck
0.712 0.287 0.000
C79 Secondary malignant neoplasm of other sites
0.711 0.289 0.000
Z44 Fitting and adjustment of external prosthetic device
0.710 0.290 0.000
C67 Malignant neoplasm of bladder
0.709 0.291 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.709 0.291 0.000
Z52 Donors of organs and tissues
0.708 0.292 0.000
Z51.9 Medical care, unspecified
0.708 0.292 0.000
Z51.6 Desensitisation to allergens
0.708 0.292 0.000
C18.8 Overlapping lesion of colon
0.707 0.293 0.000
C18.5 Splenic flexure
0.707 0.293 0.000
C18.3 Hepatic flexure
0.707 0.293 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.706 0.294 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.705 0.295 0.000
R57 Shock, not elsewhere classified
0.703 0.297 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.703 0.297 0.000
I25.6 Silent myocardial ischaemia
0.701 0.299 0.000
I25.4 Coronary artery aneurysm
0.701 0.299 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.701 0.299 0.000
D12.7 Rectosigmoid junction
0.700 0.300 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.700 0.300 0.000
R50.2 Drug-induced fever
0.700 0.300 0.000
R50.1 Persistent fever
0.700 0.300 0.000
D23.5 Skin of trunk
0.699 0.301 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.697 0.303 0.000
C77.8 Lymph nodes of multiple regions
0.696 0.304 0.000
H90-H95 Other disorders of ear
0.696 0.304 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.694 0.306 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.693 0.306 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.689 0.311 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.687 0.313 0.000
R23 Other skin changes
0.687 0.313 0.000
Z93.6 Other artificial openings of urinary tract status
0.685 0.315 0.000
Z45 Adjustment and management of implanted device
0.685 0.315 0.000
I23 Certain current complications following acute myocardial infarction
0.685 0.315 0.000
A00-A09 Intestinal infectious diseases
0.684 0.316 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.683 0.317 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.683 0.317 0.000
C31 Malignant neoplasm of accessory sinuses
0.683 0.317 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.683 0.317 0.000
C37 Malignant neoplasm of thymus
0.683 0.317 0.000
C33 Malignant neoplasm of trachea
0.683 0.317 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.683 0.317 0.000
D62 Acute posthaemorrhagic anaemia
0.682 0.318 0.000
D26 Other benign neoplasms of uterus
0.682 0.318 0.000
R20.2 Paraesthesia of skin
0.682 0.318 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.680 0.319 0.000
Z89 Acquired absence of limb
0.680 0.320 0.000
D09 Carcinoma in situ of other and unspecified sites
0.680 0.320 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.680 0.320 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.680 0.320 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.680 0.320 0.000
L53 Other erythematous conditions
0.679 0.321 0.000
D45 Polycythaemia vera
0.679 0.321 0.000
R50.8 Other specified fever
0.678 0.322 0.000
L60-L75 Disorders of skin appendages
0.676 0.324 0.000
I00-I02 Acute rheumatic fever
0.676 0.324 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.676 0.324 0.000
R90.0 Intracranial space-occupying lesion
0.676 0.324 0.000
R22.2 Localised swelling, mass and lump, trunk
0.675 0.325 0.000
L40.5 Arthropathic psoriasis
0.675 0.325 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.674 0.326 0.000
L51 Erythema multiforme
0.674 0.326 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.673 0.326 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.673 0.327 0.000
D23.2 Skin of ear and external auricular canal
0.673 0.327 0.000
S70-S79 Injuries to the hip and thigh
0.671 0.329 0.000
Z41 Procedures for purposes other than remedying health state
0.671 0.329 0.000
J03 Acute tonsillitis
0.670 0.330 0.000
D31 Benign neoplasm of eye and adnexa
0.670 0.330 0.000
D29 Benign neoplasm of male genital organs
0.670 0.330 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.670 0.330 0.000
D19 Benign neoplasm of mesothelial tissue
0.670 0.330 0.000
D16 Benign neoplasm of bone and articular cartilage
0.670 0.330 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.670 0.330 0.000
L20-L30 Dermatitis and eczema
0.670 0.330 0.000
L52 Erythema nodosum
0.669 0.331 0.000
D66 Hereditary factor VIII deficiency
0.669 0.331 0.000
R04 Haemorrhage from respiratory passages
0.669 0.331 0.000
Z42.9 Follow-up care involving plastic surgery, unspecified
0.669 0.331 0.000
Z42.8 Follow-up care involving plastic surgery of other body part
0.669 0.331 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.669 0.331 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.669 0.331 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.669 0.331 0.000
R01 Cardiac murmurs and other cardiac sounds
0.668 0.332 0.000
D12.9 Anus and anal canal
0.667 0.332 0.000
D12.1 Appendix
0.667 0.332 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.667 0.333 0.000
L10-L14 Bullous disorders
0.666 0.334 0.000
Z92.8 Personal history of other medical treatment
0.666 0.334 0.000
C77.4 Inguinal and lower limb lymph nodes
0.664 0.336 0.000
C18.2 Ascending colon
0.663 0.337 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.663 0.337 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.663 0.337 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.663 0.337 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.663 0.337 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.663 0.337 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.662 0.338 0.000
D80-D89 Certain disorders involving the immune mechanism
0.662 0.338 0.000
S90-S99 Injuries to the ankle and foot
0.662 0.338 0.000
L50 Urticaria
0.660 0.340 0.000
R61 Hyperhidrosis
0.659 0.341 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.659 0.341 0.000
B35-B49 Mycoses
0.658 0.342 0.000
D23.6 Skin of upper limb, including shoulder
0.658 0.342 0.000
C25.9 Pancreas, unspecified
0.657 0.343 0.000
Z90.3 Acquired absence of part of stomach
0.656 0.344 0.000
C50.6 Axillary tail of breast
0.656 0.344 0.000
C50.0 Nipple and areola
0.656 0.344 0.000
C34.0 Main bronchus
0.656 0.344 0.000
R59 Enlarged lymph nodes
0.656 0.344 0.000
Z90.0 Acquired absence of part of head and neck
0.655 0.345 0.000
C34.8 Overlapping lesion of bronchus and lung
0.655 0.345 0.000
C34.2 Middle lobe, bronchus or lung
0.655 0.345 0.000
I25.1 Atherosclerotic heart disease
0.654 0.346 0.000
Z99.2 Dependence on renal dialysis
0.652 0.348 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.652 0.348 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.651 0.349 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.651 0.349 0.000
R47-R49 Symptoms and signs involving speech and voice
0.650 0.350 0.000
D10 Benign neoplasm of mouth and pharynx
0.650 0.350 0.000
G90-G99 Other disorders of the nervous system
0.649 0.351 0.000
C80.9 Malignant neoplasm, unspecified
0.647 0.353 0.000
X60-X84 Intentional self-harm
0.646 0.354 0.000
D52.9 Folate deficiency anaemia, unspecified
0.645 0.355 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.644 0.356 0.000
V80-V89 Other land transport accidents
0.644 0.356 0.000
R63.4 Abnormal weight loss
0.644 0.356 0.000
R68 Other general symptoms and signs
0.641 0.358 0.000
L43 Lichen planus
0.641 0.359 0.000
V40-V49 Car occupant injured in transport accident
0.640 0.360 0.000
R45 Symptoms and signs involving emotional state
0.639 0.361 0.000
J00 Acute nasopharyngitis [common cold]
0.639 0.361 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.635 0.365 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.634 0.366 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.634 0.366 0.000
C50.8 Overlapping lesion of breast
0.632 0.368 0.000
C77.0 Lymph nodes of head, face and neck
0.631 0.369 0.000
D04.3 Skin of other and unspecified parts of face
0.631 0.369 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.631 0.369 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.631 0.369 0.000
R63.5 Abnormal weight gain
0.631 0.369 0.000
R63.3 Feeding difficulties and mismanagement
0.631 0.369 0.000
R63.2 Polyphagia
0.631 0.369 0.000
R63.1 Polydipsia
0.631 0.369 0.000
A04 Other bacterial intestinal infections
0.630 0.370 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.630 0.370 0.000
W50-W64 Exposure to animate mechanical forces
0.630 0.370 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.630 0.370 0.000
I25.5 Ischaemic cardiomyopathy
0.629 0.370 0.000
I20.9 Angina pectoris, unspecified
0.629 0.371 0.000
Z85.6 Personal history of leukaemia
0.628 0.372 0.000
R01.1 Cardiac murmur, unspecified
0.627 0.373 0.000
D46 Myelodysplastic syndromes
0.627 0.373 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.626 0.374 0.000
S60-S69 Injuries to the wrist and hand
0.625 0.375 0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.625 0.375 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.624 0.376 0.000
Z45.1 Adjustment and management of infusion pump
0.624 0.376 0.000
R04.2 Haemoptysis
0.624 0.376 0.000
G40-G47 Episodic and paroxysmal disorders
0.623 0.377 0.000
R54 Senility
0.622 0.378 0.000
Z48.0 Attention to surgical dressings and sutures
0.622 0.378 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.622 0.378 0.000
C66 Malignant neoplasm of ureter
0.622 0.378 0.000
C65 Malignant neoplasm of renal pelvis
0.622 0.378 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.622 0.378 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.621 0.379 0.000
T79-T79 Certain early complications of trauma
0.620 0.380 0.000
Y44 Agents primarily affecting blood constituents
0.620 0.380 0.000
D68.2 Hereditary deficiency of other clotting factors
0.620 0.380 0.000
D05.7 Other carcinoma in situ of breast
0.620 0.380 0.000
D05.0 Lobular carcinoma in situ
0.620 0.380 0.000
J90-J94 Other diseases of pleura
0.619 0.381 0.000
I20.1 Angina pectoris with documented spasm
0.618 0.382 0.000
D07.5 Prostate
0.614 0.386 0.000
C56 Malignant neoplasm of ovary
0.614 0.386 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.614 0.386 0.000
J30-J39 Other diseases of upper respiratory tract
0.614 0.386 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.613 0.387 0.000
R60.9 Oedema, unspecified
0.613 0.387 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.613 0.387 0.000
B25-B34 Other viral diseases
0.612 0.388 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.612 0.388 0.000
D53 Other nutritional anaemias
0.612 0.388 0.000
D32 Benign neoplasm of meninges
0.610 0.390 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.610 0.390 0.000
V10-V19 Pedal cyclist injured in transport accident
0.610 0.390 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.608 0.392 0.000
J03.9 Acute tonsillitis, unspecified
0.607 0.393 0.000
S10-S19 Injuries to the neck
0.606 0.394 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.604 0.396 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.603 0.397 0.000
L54 Erythema in diseases classified elsewhere
0.603 0.397 0.000
Z92.9 Personal history of medical treatment, unspecified
0.603 0.397 0.000
Z92.5 Personal history of rehabilitation measures
0.603 0.397 0.000
H72 Perforation of tympanic membrane
0.603 0.397 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.602 0.398 0.000
Z99.3 Dependence on wheelchair
0.602 0.398 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.602 0.398 0.000
J01 Acute sinusitis
0.602 0.398 0.000
D37.6 Liver, gallbladder and bile ducts
0.602 0.398 0.000
D37.5 Rectum
0.602 0.398 0.000
D37.3 Appendix
0.602 0.398 0.000
D37.2 Small intestine
0.602 0.398 0.000
D37.1 Stomach
0.602 0.398 0.000
D37.0 Lip, oral cavity and pharynx
0.602 0.398 0.000
D04.6 Skin of upper limb, including shoulder
0.601 0.399 0.000
L44 Other papulosquamous disorders
0.601 0.399 0.000
L41 Parapsoriasis
0.601 0.399 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.601 0.399 0.000
L42 Pityriasis rosea
0.601 0.399 0.000
R52 Pain, not elsewhere classified
0.600 0.400 0.000
Z43 Attention to artificial openings
0.600 0.400 0.000
H80-H83 Diseases of inner ear
0.599 0.401 0.000
A04.8 Other specified bacterial intestinal infections
0.599 0.401 0.000
D67 Hereditary factor IX deficiency
0.598 0.402 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.598 0.402 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.598 0.402 0.000
Y35-Y36 Legal intervention and operations of war
0.598 0.402 0.000
Y10-Y34 Event of undetermined intent
0.598 0.402 0.000
Y00-Y09 Assault
0.598 0.402 0.000
X85-X99 Assault
0.598 0.402 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.598 0.402 0.000
X50-X57 Overexertion, travel and privation
0.598 0.402 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.598 0.402 0.000
X30-X39 Exposure to forces of nature
0.598 0.402 0.000
X20-X29 Contact with venomous animals and plants
0.598 0.402 0.000
X10-X19 Contact with heat and hot substances
0.598 0.402 0.000
X00-X09 Exposure to smoke, fire and flames
0.598 0.402 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.598 0.402 0.000
W75-W84 Other accidental threats to breathing
0.598 0.402 0.000
W65-W74 Accidental drowning and submersion
0.598 0.402 0.000
V98-V99 Other and unspecified transport accidents
0.598 0.402 0.000
V95-V97 Air and space transport accidents
0.598 0.402 0.000
V90-V94 Water transport accidents
0.598 0.402 0.000
V70-V79 Bus occupant injured in transport accident
0.598 0.402 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.598 0.402 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.598 0.402 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.598 0.402 0.000
V20-V29 Motorcycle rider injured in transport accident
0.598 0.402 0.000
V01-V09 Pedestrian injured in transport accident
0.598 0.402 0.000
D06 Carcinoma in situ of cervix uteri
0.598 0.402 0.000
Z40 Prophylactic surgery
0.597 0.403 0.000
D36 Benign neoplasm of other and unspecified sites
0.596 0.403 0.000
L40.9 Psoriasis, unspecified
0.596 0.404 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.596 0.404 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.595 0.404 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.595 0.405 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.594 0.405 0.000
I05-I09 Chronic rheumatic heart diseases
0.594 0.406 0.000
R53 Malaise and fatigue
0.594 0.406 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.594 0.406 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.594 0.406 0.000
D21.9 Connective and other soft tissue, unspecified
0.594 0.406 0.000
D21.6 Connective and other soft tissue of trunk, unspecified
0.594 0.406 0.000
D21.5 Connective and other soft tissue of pelvis
0.594 0.406 0.000
D21.4 Connective and other soft tissue of abdomen
0.594 0.406 0.000
D21.3 Connective and other soft tissue of thorax
0.594 0.406 0.000
D21.0 Connective and other soft tissue of head, face and neck
0.594 0.406 0.000
R40 Somnolence, stupor and coma
0.593 0.407 0.000
R60.0 Localised oedema
0.593 0.407 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.593 0.407 0.000
Z46 Fitting and adjustment of other devices
0.593 0.407 0.000
D61.9 Aplastic anaemia, unspecified
0.591 0.408 0.000
T33-T35 Frostbite
0.591 0.409 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.591 0.409 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.591 0.409 0.000
T00-T07 Injuries involving multiple body regions
0.591 0.409 0.000
S27 Injury of other and unspecified intrathoracic organs
0.591 0.409 0.000
C54 Malignant neoplasm of corpus uteri
0.590 0.410 0.000
C43 Malignant melanoma of skin
0.590 0.410 0.000
Chapter V Mental and behavioural disorders
0.589 0.411 0.000
C60-C63 Malignant neoplasms of male genital organs
0.588 0.412 0.000
C16 Malignant neoplasm of stomach
0.588 0.412 0.000
R50.0 Fever with chills
0.588 0.412 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.588 0.412 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.588 0.412 0.000
D34 Benign neoplasm of thyroid gland
0.587 0.413 0.000
S20 Superficial injury of thorax
0.587 0.413 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.587 0.413 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.587 0.413 0.000
G70-G73 Diseases of myoneural junction and muscle
0.586 0.414 0.000
J04 Acute laryngitis and tracheitis
0.586 0.414 0.000
D23.9 Skin, unspecified
0.582 0.418 0.000
D23.0 Skin of lip
0.582 0.418 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.582 0.418 0.000
D11.0 Parotid gland
0.582 0.418 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.582 0.418 0.000
D47.1 Chronic myeloproliferative disease
0.581 0.419 0.000
Z93.3 Colostomy status
0.581 0.419 0.000
C50.2 Upper-inner quadrant of breast
0.579 0.421 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.577 0.423 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.576 0.424 0.000
Z93.0 Tracheostomy status
0.575 0.425 0.000
Y43 Primarily systemic agents
0.575 0.425 0.000
R94 Abnormal results of function studies
0.574 0.426 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.574 0.426 0.000
R46 Symptoms and signs involving appearance and behaviour
0.573 0.426 0.000
R43 Disturbances of smell and taste
0.573 0.426 0.000
D37.7 Other digestive organs
0.573 0.427 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.572 0.428 0.000
L40.0 Psoriasis vulgaris
0.572 0.428 0.000
R74 Abnormal serum enzyme levels
0.571 0.429 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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