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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs358592
log Bayes Factor = 0.277296
Chromosome 4   position 21,476,990  (GRCh37) Explore rs358592 on Ensembl!
Variant rs358592 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.4 With neurological complications
0.000 0.484 0.516
E11 Non-insulin-dependent diabetes mellitus
0.000 0.486 0.514
E10-E14 Diabetes mellitus
0.000 0.491 0.509
E10 Insulin-dependent diabetes mellitus
0.000 0.503 0.497
E11.6 With other specified complications
0.000 0.526 0.474
E14 Unspecified diabetes mellitus
0.000 0.526 0.474
E10.9 Without complications
0.000 0.527 0.473
E10.4 With neurological complications
0.000 0.527 0.473
E11.5 With peripheral circulatory complications
0.000 0.532 0.468
E14.3 With ophthalmic complications
0.000 0.541 0.459
E10.3 With ophthalmic complications
0.000 0.574 0.426
E11.8 With unspecified complications
0.000 0.577 0.423
E11.2 With renal complications
0.000 0.595 0.405
E10.6 With other specified complications
0.000 0.629 0.371
E13 Other specified diabetes mellitus
0.000 0.629 0.371
E12 Malnutrition-related diabetes mellitus
0.000 0.635 0.365
E11.7 With multiple complications
0.000 0.641 0.359
E11.0 With coma
0.000 0.644 0.356
E14.6 With other specified complications
0.000 0.645 0.355
E14.8 With unspecified complications
0.000 0.646 0.354
E14.5 With peripheral circulatory complications
0.000 0.649 0.351
E14.7 With multiple complications
0.000 0.660 0.340
E10.2 With renal complications
0.000 0.662 0.338
E14.4 With neurological complications
0.000 0.668 0.332
E14.2 Withrenal complications
0.000 0.671 0.329
E10.8 With unspecified complications
0.000 0.674 0.326
E10.0 With coma
0.000 0.675 0.325
E10.5 With peripheral circulatory complications
0.000 0.677 0.323
E14.1 With ketoacidosis
0.000 0.678 0.322
E10.7 With multiple complications
0.000 0.681 0.319
E14.0 With coma
0.000 0.685 0.315
E13.3 With ophthalmic complications
0.000 0.695 0.305
E11.3 With ophthalmic complications
0.000 0.724 0.276
E14.9 Without complications
0.000 0.726 0.274
E27 Other disorders of adrenal gland
0.000 0.726 0.274
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.730 0.270
E20-E35 Disorders of other endocrine glands
0.000 0.730 0.270
E13.8 With unspecified complications
0.000 0.734 0.266
E13.7 With multiple complications
0.000 0.734 0.266
E13.6 With other specified complications
0.000 0.734 0.266
E13.5 With peripheral circulatory complications
0.000 0.734 0.266
E13.4 With neurological complications
0.000 0.734 0.266
E13.2 With renal complications
0.000 0.734 0.266
E13.1 With ketoacidosis
0.000 0.734 0.266
E13.0 With coma
0.000 0.734 0.266
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.738 0.262
E12.9 Without complications
0.000 0.738 0.262
E12.8 With unspecified complications
0.000 0.738 0.262
E12.7 With multiple complications
0.000 0.738 0.262
E12.6 With other specified complications
0.000 0.738 0.262
E12.5 With peripheral circulatory complications
0.000 0.738 0.262
E12.4 With neurological complications
0.000 0.738 0.262
E12.3 With ophthalmic complications
0.000 0.738 0.262
E12.2 With renal complications
0.000 0.738 0.262
E12.1 With ketoacidosis
0.000 0.738 0.262
E12.0 With coma
0.000 0.738 0.262
E27.9 Disorder of adrenal gland, unspecified
0.000 0.748 0.252
E10.1 With ketoacidosis
0.000 0.752 0.248
E26 Hyperaldosteronism
0.000 0.753 0.247
E11.1 With ketoacidosis
0.000 0.753 0.247
E24 Cushing's syndrome
0.000 0.755 0.245
E27.8 Other specified disorders of adrenal gland
0.000 0.760 0.239
E26.0 Primary hyperaldosteronism
0.000 0.768 0.232
E34 Other endocrine disorders
0.000 0.784 0.216
E13.9 Without complications
0.000 0.786 0.214
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.788 0.212
E31 Polyglandular dysfunction
0.000 0.799 0.201
E27.2 Addisonian crisis
0.000 0.799 0.200
E24.9 Cushing's syndrome, unspecified
0.000 0.800 0.200
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.802 0.197
E27.5 Adrenomedullary hyperfunction
0.000 0.804 0.196
E27.0 Other adrenocortical overactivity
0.000 0.804 0.196
E24.8 Other Cushing's syndrome
0.000 0.805 0.195
E24.0 Pituitary-dependent Cushing's disease
0.000 0.806 0.194
E50-E64 Other nutritional deficiencies
0.000 0.806 0.194
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.807 0.193
E30 Disorders of puberty, not elsewhere classified
0.000 0.807 0.193
E24.2 Drug-induced Cushing's syndrome
0.000 0.808 0.192
E34.8 Other specified endocrine disorders
0.000 0.809 0.191
E65-E68 Obesity and other hyperalimentation
0.000 0.811 0.189
E29 Testicular dysfunction
0.000 0.814 0.186
E27.1 Primary adrenocortical insufficiency
0.000 0.816 0.184
E40-E46 Malnutrition
0.000 0.817 0.183
E32 Diseases of thymus
0.000 0.818 0.182
E26.8 Other hyperaldosteronism
0.000 0.822 0.178
E26.1 Secondary hyperaldosteronism
0.000 0.822 0.178
E26.9 Hyperaldosteronism, unspecified
0.000 0.823 0.177
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.824 0.176
E24.3 Ectopic ACTH syndrome
0.000 0.824 0.176
E24.1 Nelson's syndrome
0.000 0.824 0.176
E25 Adrenogenital disorders
0.000 0.828 0.172
E61 Deficiency of other nutrient elements
0.000 0.832 0.168
E20 Hypoparathyroidism
0.000 0.832 0.168
E34.3 Short stature, not elsewhere classified
0.000 0.833 0.167
E28 Ovarian dysfunction
0.000 0.841 0.159
E61.1 Iron deficiency
0.000 0.843 0.157
E53 Deficiency of other B group vitamins
0.000 0.844 0.156
E34.5 Androgen resistance syndrome
0.000 0.845 0.155
E34.4 Constitutional tall stature
0.000 0.845 0.155
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.845 0.155
E34.1 Other hypersecretion of intestinal hormones
0.000 0.845 0.155
E31.0 Autoimmune polyglandular failure
0.000 0.848 0.152
E16 Other disorders of pancreatic internal secretion
0.000 0.855 0.145
E31.9 Polyglandular dysfunction, unspecified
0.000 0.856 0.144
E31.8 Other polyglandular dysfunction
0.000 0.856 0.144
E31.1 Polyglandular hyperfunction
0.000 0.856 0.144
E29.9 Testicular dysfunction, unspecified
0.000 0.858 0.142
E15 Nondiabetic hypoglycaemic coma
0.000 0.858 0.142
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.861 0.139
E63 Other nutritional deficiencies
0.000 0.861 0.139
E50 Vitamin A deficiency
0.000 0.861 0.139
E60 Dietary zinc deficiency
0.000 0.861 0.139
E59 Dietary selenium deficiency
0.000 0.861 0.139
E52 Niacin deficiency [pellagra]
0.000 0.861 0.139
E30.9 Disorder of puberty, unspecified
0.000 0.861 0.139
E30.8 Other disorders of puberty
0.000 0.861 0.139
E30.1 Precocious puberty
0.000 0.861 0.139
E30.0 Delayed puberty
0.000 0.861 0.139
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.861 0.139
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.861 0.139
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.861 0.139
E22 Hyperfunction of pituitary gland
0.000 0.861 0.139
E56 Other vitamin deficiencies
0.000 0.864 0.136
E67 Other hyperalimentation
0.000 0.864 0.136
E68 Sequelae of hyperalimentation
0.000 0.864 0.136
E65 Localised adiposity
0.000 0.865 0.135
E29.8 Other testicular dysfunction
0.000 0.866 0.133
E29.0 Testicular hyperfunction
0.000 0.866 0.133
E34.0 Carcinoid syndrome
0.000 0.867 0.133
E34.9 Endocrine disorder, unspecified
0.000 0.867 0.133
E58 Dietary calcium deficiency
0.000 0.867 0.133
E66 Obesity
0.000 0.868 0.132
E53.8 Deficiency of other specified B group vitamins
0.000 0.868 0.132
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.869 0.131
E45 Retarded development following protein-energy malnutrition
0.000 0.869 0.131
E43 Unspecified severe protein-energy malnutrition
0.000 0.869 0.131
E42 Marasmic kwashiorkor
0.000 0.869 0.131
E41 Nutritional marasmus
0.000 0.869 0.131
E40 Kwashiorkor
0.000 0.869 0.131
E32.9 Disease of thymus, unspecified
0.000 0.869 0.131
E32.1 Abscess of thymus
0.000 0.869 0.131
E32.0 Persistent hyperplasia of thymus
0.000 0.869 0.131
E16.2 Hypoglycaemia, unspecified
0.000 0.869 0.131
E51 Thiamine deficiency
0.000 0.872 0.128
E25.9 Adrenogenital disorder, unspecified
0.000 0.876 0.123
E25.8 Other adrenogenital disorders
0.000 0.876 0.123
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.877 0.123
E61.9 Deficiency of nutrient element, unspecified
0.000 0.879 0.121
E61.8 Deficiency of other specified nutrient elements
0.000 0.879 0.121
E61.7 Deficiency of multiple nutrient elements
0.000 0.879 0.121
E61.6 Vanadium deficiency
0.000 0.879 0.121
E61.5 Molybdenum deficiency
0.000 0.879 0.121
E61.4 Chromium deficiency
0.000 0.879 0.121
E61.3 Manganese deficiency
0.000 0.879 0.121
E61.0 Copper deficiency
0.000 0.879 0.121
E20.8 Other hypoparathyroidism
0.000 0.879 0.121
E20.1 Pseudohypoparathyroidism
0.000 0.879 0.121
E20.0 Idiopathic hypoparathyroidism
0.000 0.879 0.121
E46 Unspecified protein-energy malnutrition
0.000 0.880 0.120
E32.8 Other diseases of thymus
0.000 0.880 0.120
E66.8 Other obesity
0.000 0.881 0.119
E55 Vitamin D deficiency
0.000 0.884 0.116
E29.1 Testicular hypofunction
0.000 0.886 0.114
E28.9 Ovarian dysfunction, unspecified
0.000 0.886 0.114
E28.8 Other ovarian dysfunction
0.000 0.886 0.114
E28.1 Androgen excess
0.000 0.886 0.114
E28.0 Oestrogen excess
0.000 0.886 0.114
E53.1 Pyridoxine deficiency
0.000 0.888 0.112
E53.0 Riboflavin deficiency
0.000 0.888 0.112
E54 Ascorbic acid deficiency
0.000 0.890 0.109
E66.0 Obesity due to excess calories
0.000 0.891 0.109
E53.9 Vitamin B deficiency, unspecified
0.000 0.891 0.108
G59.0 Diabetic mononeuropathy
0.000 0.895 0.105
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.896 0.104
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.896 0.104
E16.4 Abnormal secretion of gastrin
0.000 0.896 0.104
E16.3 Increased secretion of glucagon
0.000 0.896 0.104
E22.0 Acromegaly and pituitary gigantism
0.000 0.896 0.104
E21.2 Other hyperparathyroidism
0.000 0.896 0.104
E28.3 Primary ovarian failure
0.000 0.897 0.103
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.898 0.102
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.899 0.100
E50.9 Vitamin A deficiency, unspecified
0.000 0.900 0.100
E50.8 Other manifestations of vitamin A deficiency
0.000 0.900 0.100
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.900 0.100
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.900 0.100
E50.5 Vitamin A deficiency with night blindness
0.000 0.900 0.100
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.900 0.100
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.900 0.100
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.900 0.100
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.900 0.100
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.900 0.100
E63.9 Nutritional deficiency, unspecified
0.000 0.900 0.100
E63.8 Other specified nutritional deficiencies
0.000 0.900 0.100
E63.1 Imbalance of constituents of food intake
0.000 0.900 0.100
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.900 0.100
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.900 0.100
E64.8 Sequelae of other nutritional deficiencies
0.000 0.900 0.100
E64.3 Sequelae of rickets
0.000 0.900 0.100
E64.2 Sequelae of vitamin C deficiency
0.000 0.900 0.100
E64.1 Sequelae of vitamin A deficiency
0.000 0.900 0.100
E64.0 Sequelae of protein-energy malnutrition
0.000 0.900 0.100
E22.8 Other hyperfunction of pituitary gland
0.000 0.900 0.100
E23 Hypofunction and other disorders of pituitary gland
0.000 0.901 0.099
E56.9 Vitamin deficiency, unspecified
0.000 0.902 0.097
E56.8 Deficiency of other vitamins
0.000 0.902 0.097
E56.0 Deficiency of vitamin E
0.000 0.902 0.097
E67.8 Other specified hyperalimentation
0.000 0.902 0.097
E67.3 Hypervitaminosis D
0.000 0.902 0.097
E67.2 Megavitamin-B6 syndrome
0.000 0.902 0.097
E67.1 Hypercarotenaemia
0.000 0.902 0.097
E67.0 Hypervitaminosis A
0.000 0.902 0.097
E21.4 Other specified disorders of parathyroid gland
0.000 0.904 0.096
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.904 0.096
E28.2 Polycystic ovarian syndrome
0.000 0.904 0.096
E20.9 Hypoparathyroidism, unspecified
0.000 0.905 0.095
E66.1 Drug-induced obesity
0.000 0.905 0.095
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.905 0.095
E44.1 Mild protein-energy malnutrition
0.000 0.906 0.094
E44.0 Moderate protein-energy malnutrition
0.000 0.906 0.094
E56.1 Deficiency of vitamin K
0.000 0.906 0.094
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.907 0.093
E61.2 Magnesium deficiency
0.000 0.907 0.092
E51.9 Thiamine deficiency, unspecified
0.000 0.908 0.092
E51.8 Other manifestations of thiamine deficiency
0.000 0.908 0.092
E51.1 Beriberi
0.000 0.908 0.092
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.910 0.090
E55.0 Rickets, active
0.000 0.916 0.084
E51.2 Wernicke's encephalopathy
0.000 0.919 0.081
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.920 0.080
E23.7 Disorder of pituitary gland, unspecified
0.000 0.927 0.073
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.929 0.071
E23.1 Drug-induced hypopituitarism
0.000 0.929 0.071
E23.6 Other disorders of pituitary gland
0.000 0.929 0.071
E55.9 Vitamin D deficiency, unspecified
0.000 0.939 0.061
E11.9 Without complications
0.000 0.941 0.059
E16.1 Other hypoglycaemia
0.001 0.941 0.058
E23.2 Diabetes insipidus
0.000 0.946 0.054
E22.1 Hyperprolactinaemia
0.001 0.949 0.050
G59 Mononeuropathy in diseases classified elsewhere
0.000 0.955 0.045
G59.8 Other mononeuropathies in diseases classified elsewhere
0.000 0.968 0.032
E00-E07 Disorders of thyroid gland
0.000 0.979 0.021
E23.0 Hypopituitarism
0.001 0.980 0.019
E21.0 Primary hyperparathyroidism
0.000 0.981 0.019
Z99.1 Dependence on respirator
0.017 0.983 0.000
A04.8 Other specified bacterial intestinal infections
0.000 0.984 0.016
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.985 0.015
E00 Congenital iodine-deficiency syndrome
0.000 0.985 0.015
E21.3 Hyperparathyroidism, unspecified
0.001 0.986 0.013
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.986 0.014
S32.50 Fracture of pubis (closed)
0.014 0.986 0.000
E03 Other hypothyroidism
0.000 0.987 0.013
E06 Thyroiditis
0.000 0.987 0.012
E03.8 Other specified hypothyroidism
0.000 0.989 0.011
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.989 0.011
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.989 0.011
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.989 0.011
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.989 0.011
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.989 0.011
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.989 0.011
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.989 0.011
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.989 0.011
E07 Other disorders of thyroid
0.000 0.989 0.011
E06.9 Thyroiditis, unspecified
0.000 0.989 0.011
E03.1 Congenital hypothyroidism without goitre
0.000 0.990 0.010
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.990 0.010
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.990 0.010
E03.5 Myxoedema coma
0.000 0.990 0.009
E03.4 Atrophy of thyroid (acquired)
0.000 0.990 0.009
E03.3 Postinfectious hypothyroidism
0.000 0.990 0.009
E06.1 Subacute thyroiditis
0.000 0.991 0.009
E06.4 Drug-induced thyroiditis
0.000 0.991 0.009
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.991 0.009
E06.0 Acute thyroiditis
0.000 0.991 0.009
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.991 0.008
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.992 0.008
E06.5 Other chronic thyroiditis
0.000 0.992 0.008
E07.1 Dyshormogenetic goitre
0.000 0.992 0.008
E07.0 Hypersecretion of calcitonin
0.000 0.992 0.008
S32.5 Fracture of pubis
0.008 0.992 0.000
M86.9 Osteomyelitis, unspecified
0.000 0.992 0.008
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)
0.000 0.993 0.007
E05.8 Other thyrotoxicosis
0.000 0.993 0.007
G63.2 Diabetic polyneuropathy
0.000 0.993 0.007
E07.9 Disorder of thyroid, unspecified
0.000 0.993 0.007
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.993 0.007
M86.94 Osteomyelitis, unspecified (Hand)
0.000 0.993 0.007
M86.96 Osteomyelitis, unspecified (Lower leg)
0.000 0.994 0.006
E05.5 Thyroid crisis or storm
0.000 0.994 0.006
E05.4 Thyrotoxicosis factitia
0.000 0.994 0.006
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.994 0.006
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.000 0.994 0.006
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.994 0.006
S32.51 Fracture of pubis (open)
0.006 0.994 0.000
M90.7 Fracture of bone in neoplastic disease
0.000 0.994 0.006
M86.93 Osteomyelitis, unspecified (Forearm)
0.000 0.994 0.006
M86.92 Osteomyelitis, unspecified (Upper arm)
0.000 0.994 0.006
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.000 0.994 0.006
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.000 0.994 0.006
C43.6 Malignant melanoma of upper limb, including shoulder
0.006 0.994 0.000
C49.2 Connective and soft tissue of lower limb, including hip
0.006 0.994 0.000
M86 Osteomyelitis
0.000 0.994 0.006
M86.98 Osteomyelitis, unspecified (Other)
0.000 0.994 0.006
E07.8 Other specified disorders of thyroid
0.000 0.995 0.005
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.995 0.005
M90.72 Fracture of bone in neoplastic disease (Upper arm)
0.000 0.995 0.005
M90 Osteopathies in diseases classified elsewhere
0.000 0.995 0.005
M90.71 Fracture of bone in neoplastic disease (Shoulder region)
0.000 0.995 0.005
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.000 0.995 0.005
M41.99 Scoliosis, unspecified (Site unspecified)
0.000 0.995 0.005
A04 Other bacterial intestinal infections
0.000 0.995 0.005
M86.4 Chronic osteomyelitis with draining sinus
0.000 0.995 0.005
M86-M90 Other osteopathies
0.000 0.995 0.005
H57.1 Ocular pain
0.005 0.995 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.995 0.005
M88.9 Paget's disease of bone, unspecified
0.000 0.995 0.005
A04.5 Campylobacter enteritis
0.000 0.995 0.005
M90.79 Fracture of bone in neoplastic disease (Site unspecified)
0.000 0.995 0.004
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)
0.000 0.995 0.004
M90.74 Fracture of bone in neoplastic disease (Hand)
0.000 0.995 0.004
M90.73 Fracture of bone in neoplastic disease (Forearm)
0.000 0.995 0.004
M86.5 Other chronic haematogenous osteomyelitis
0.000 0.995 0.004
M86.3 Chronic multifocal osteomyelitis
0.000 0.995 0.004
M86.2 Subacute osteomyelitis
0.000 0.995 0.004
M86.0 Acute haematogenous osteomyelitis
0.000 0.995 0.004
L03.2 Cellulitis of face
0.000 0.995 0.005
M86.1 Other acute osteomyelitis
0.000 0.995 0.004
M88 Paget's disease of bone [osteitis deformans]
0.000 0.996 0.004
T51.0 Ethanol
0.004 0.996 0.000
E06.3 Autoimmune thyroiditis
0.000 0.996 0.004
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.996 0.004
M86.6 Other chronic osteomyelitis
0.000 0.996 0.004
C49 Malignant neoplasm of other connective and soft tissue
0.004 0.996 0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)
0.000 0.996 0.004
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.000 0.996 0.004
M90.76 Fracture of bone in neoplastic disease (Lower leg)
0.000 0.996 0.004
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)
0.000 0.996 0.004
C49.0 Connective and soft tissue of head, face and neck
0.004 0.996 0.000
C49.1 Connective and soft tissue of upper limb, including shoulder
0.004 0.996 0.000
M86.8 Other osteomyelitis
0.000 0.996 0.004
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)
0.000 0.996 0.004
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.004 0.996 0.000
M90.6 Osteitis deformans in neoplastic disease
0.000 0.996 0.004
M90.5 Osteonecrosis in other diseases classified elsewhere
0.000 0.996 0.004
M90.4 Osteonecrosis due to heamoglobinopathy
0.000 0.996 0.004
M90.3 Osteonecrosis in caisson disease
0.000 0.996 0.004
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.000 0.996 0.004
M90.0 Tuberculosis of bone
0.000 0.996 0.004
M88.99 Paget's disease of bone, unspecified (Site unspecified)
0.000 0.996 0.004
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.000 0.996 0.004
S32 Fracture of lumbar spine and pelvis
0.004 0.996 0.000
M90.8 Osteopathy in other diseases classified elsewhere
0.000 0.996 0.004
L03.3 Cellulitis of trunk
0.000 0.996 0.004
A04.6 Enteritis due to Yersinia enterocolitica
0.000 0.996 0.004
A04.3 Enterohaemorrhagic Escherichia coli infection
0.000 0.996 0.004
A04.2 Enteroinvasive Escherichia coli infection
0.000 0.996 0.004
A04.1 Enterotoxigenic Escherichia coli infection
0.000 0.996 0.004
A04.0 Enteropathogenic Escherichia coli infection
0.000 0.996 0.004
M87 Osteonecrosis
0.000 0.996 0.004
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)
0.000 0.996 0.003
M86.48 Chronic osteomyelitis with draining sinus (Other)
0.000 0.996 0.003
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)
0.000 0.996 0.003
M86.44 Chronic osteomyelitis with draining sinus (Hand)
0.000 0.996 0.003
M86.43 Chronic osteomyelitis with draining sinus (Forearm)
0.000 0.996 0.003
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)
0.000 0.996 0.003
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)
0.000 0.996 0.003
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)
0.000 0.996 0.003
M41.96 Scoliosis, unspecified (Lumbar region)
0.000 0.996 0.004
M90.1 Periostitis in other infectious diseases classified elsewhere
0.000 0.996 0.003
Z82.3 Family history of stroke
0.000 0.996 0.004
T51 Toxic effect of alcohol
0.004 0.996 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.000 0.996 0.003
G63.6 Polyneuropathy in other musculoskeletal disorders
0.000 0.996 0.003
G63.5 Polyneuropathy in systemic connective tissue disorders
0.000 0.996 0.003
G63.4 Polyneuropathy in nutritional deficiency
0.000 0.996 0.003
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.000 0.996 0.003
G63.1 Polyneuropathy in neoplastic disease
0.000 0.996 0.003
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.000 0.996 0.003
M88.98 Paget's disease of bone, unspecified (Other)
0.000 0.996 0.003
M88.97 Paget's disease of bone, unspecified (Ankle and foot)
0.000 0.996 0.003
M88.96 Paget's disease of bone, unspecified (Lower leg)
0.000 0.996 0.003
M88.94 Paget's disease of bone, unspecified (Hand)
0.000 0.996 0.003
M88.93 Paget's disease of bone, unspecified (Forearm)
0.000 0.996 0.003
M88.92 Paget's disease of bone, unspecified (Upper arm)
0.000 0.996 0.003
M88.91 Paget's disease of bone, unspecified (Shoulder region)
0.000 0.996 0.003
S32.7 Multiple fractures of lumbar spine and pelvis
0.004 0.996 0.000
M90.78 Fracture of bone in neoplastic disease (Other)
0.000 0.996 0.003
M41.9 Scoliosis, unspecified
0.000 0.996 0.004
L03 Cellulitis
0.000 0.996 0.004
N89.8 Other specified noninflammatory disorders of vagina
0.000 0.996 0.004
T51.9 Alcohol, unspecified
0.004 0.996 0.000
M86.09 Acute haematogenous osteomyelitis (Site unspecified)
0.000 0.996 0.003
M86.08 Acute haematogenous osteomyelitis (Other)
0.000 0.996 0.003
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)
0.000 0.996 0.003
M86.06 Acute haematogenous osteomyelitis (Lower leg)
0.000 0.996 0.003
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)
0.000 0.996 0.003
M86.04 Acute haematogenous osteomyelitis (Hand)
0.000 0.996 0.003
M86.03 Acute haematogenous osteomyelitis (Forearm)
0.000 0.996 0.003
M86.02 Acute haematogenous osteomyelitis (Upper arm)
0.000 0.996 0.003
M86.01 Acute haematogenous osteomyelitis (Shoulder region)
0.000 0.996 0.003
M86.00 Acute haematogenous osteomyelitis (Multiple sites)
0.000 0.996 0.003
M86.29 Subacute osteomyelitis (Site unspecified)
0.000 0.996 0.003
M86.28 Subacute osteomyelitis (Other)
0.000 0.996 0.003
M86.27 Subacute osteomyelitis (Ankle and foot)
0.000 0.996 0.003
M86.26 Subacute osteomyelitis (Lower leg)
0.000 0.996 0.003
M86.25 Subacute osteomyelitis (Pelvic region and thigh)
0.000 0.996 0.003
M86.24 Subacute osteomyelitis (Hand)
0.000 0.996 0.003
M86.23 Subacute osteomyelitis (Forearm)
0.000 0.996 0.003
M86.22 Subacute osteomyelitis (Upper arm)
0.000 0.996 0.003
M86.21 Subacute osteomyelitis (Shoulder region)
0.000 0.996 0.003
M86.20 Subacute osteomyelitis (Multiple sites)
0.000 0.996 0.003
M86.39 Chronic multifocal osteomyelitis (Site unspecified)
0.000 0.996 0.003
M86.38 Chronic multifocal osteomyelitis (Other)
0.000 0.996 0.003
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)
0.000 0.996 0.003
M86.36 Chronic multifocal osteomyelitis (Lower leg)
0.000 0.996 0.003
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)
0.000 0.996 0.003
M86.34 Chronic multifocal osteomyelitis (Hand)
0.000 0.996 0.003
M86.33 Chronic multifocal osteomyelitis (Forearm)
0.000 0.996 0.003
M86.32 Chronic multifocal osteomyelitis (Upper arm)
0.000 0.996 0.003
M86.31 Chronic multifocal osteomyelitis (Shoulder region)
0.000 0.996 0.003
M86.30 Chronic multifocal osteomyelitis (Multiple sites)
0.000 0.996 0.003
M86.59 Other chronic haematogenous osteomyelitis (Site unspecified)
0.000 0.996 0.003
M86.58 Other chronic haematogenous osteomyelitis (Other)
0.000 0.996 0.003
M86.57 Other chronic haematogenous osteomyelitis (Ankle and foot)
0.000 0.996 0.003
M86.56 Other chronic haematogenous osteomyelitis (Lower leg)
0.000 0.996 0.003
M86.55 Other chronic haematogenous osteomyelitis (Pelvic region and thigh)
0.000 0.996 0.003
M86.54 Other chronic haematogenous osteomyelitis (Hand)
0.000 0.996 0.003
M86.53 Other chronic haematogenous osteomyelitis (Forearm)
0.000 0.996 0.003
M86.52 Other chronic haematogenous osteomyelitis (Upper arm)
0.000 0.996 0.003
M86.51 Other chronic haematogenous osteomyelitis (Shoulder region)
0.000 0.996 0.003
M86.50 Other chronic haematogenous osteomyelitis (Multiple sites)
0.000 0.996 0.003
Z99.0 Dependence on aspirator
0.003 0.996 0.000
M86.19 Other acute osteomyelitis (Site unspecified)
0.000 0.996 0.003
M86.18 Other acute osteomyelitis (Other)
0.000 0.996 0.003
M86.16 Other acute osteomyelitis (Lower leg)
0.000 0.996 0.003
M86.15 Other acute osteomyelitis (Pelvic region and thigh)
0.000 0.996 0.003
M86.14 Other acute osteomyelitis (Hand)
0.000 0.996 0.003
M86.13 Other acute osteomyelitis (Forearm)
0.000 0.996 0.003
M86.12 Other acute osteomyelitis (Upper arm)
0.000 0.996 0.003
M86.11 Other acute osteomyelitis (Shoulder region)
0.000 0.996 0.003
M86.10 Other acute osteomyelitis (Multiple sites)
0.000 0.996 0.003
M86.17 Other acute osteomyelitis (Ankle and foot)
0.000 0.996 0.003
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)
0.000 0.996 0.003
C49.6 Connective and soft tissue of trunk, unspecified
0.003 0.996 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.996 0.003
K85.9 Acute pancreatitis, unspecified
0.003 0.997 0.000
C45.9 Mesothelioma, unspecified
0.003 0.997 0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)
0.003 0.997 0.000
C71.9 Brain, unspecified
0.000 0.997 0.003
A04.9 Bacterial intestinal infection, unspecified
0.000 0.997 0.003
C49.8 Overlapping lesion of connective and soft tissue
0.003 0.997 0.000
L03.9 Cellulitis, unspecified
0.000 0.997 0.003
M87.9 Osteonecrosis, unspecified
0.000 0.997 0.003
M86.64 Other chronic osteomyelitis (Hand)
0.000 0.997 0.003
M86.63 Other chronic osteomyelitis (Forearm)
0.000 0.997 0.003
M86.62 Other chronic osteomyelitis (Upper arm)
0.000 0.997 0.003
M86.61 Other chronic osteomyelitis (Shoulder region)
0.000 0.997 0.003
M86.60 Other chronic osteomyelitis (Multiple sites)
0.000 0.997 0.003
C02.9 Tongue, unspecified
0.003 0.997 0.000
R44.0 Auditory hallucinations
0.000 0.997 0.003
M86.85 Other osteomyelitis (Pelvic region and thigh)
0.000 0.997 0.003
M86.68 Other chronic osteomyelitis (Other)
0.000 0.997 0.003
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.997 0.003
M88.0 Paget's disease of skull
0.000 0.997 0.003
C49.4 Connective and soft tissue of abdomen
0.003 0.997 0.000
M90.61 Osteitis deformans in neoplastic disease (Shoulder region)
0.000 0.997 0.003
Z99.8 Dependence on other enabling machines and devices
0.003 0.997 0.000
M86.69 Other chronic osteomyelitis (Site unspecified)
0.000 0.997 0.003
S32.4 Fracture of acetabulum
0.003 0.997 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.003 0.997 0.000
M86.89 Other osteomyelitis (Site unspecified)
0.000 0.997 0.003
M86.88 Other osteomyelitis (Other)
0.000 0.997 0.003
M86.84 Other osteomyelitis (Hand)
0.000 0.997 0.003
M86.83 Other osteomyelitis (Forearm)
0.000 0.997 0.003
M86.82 Other osteomyelitis (Upper arm)
0.000 0.997 0.003
M86.81 Other osteomyelitis (Shoulder region)
0.000 0.997 0.003
M86.80 Other osteomyelitis (Multiple sites)
0.000 0.997 0.003
M90.69 Osteitis deformans in neoplastic disease (Site unspecified)
0.000 0.997 0.003
M90.68 Osteitis deformans in neoplastic disease (Other)
0.000 0.997 0.003
M90.67 Osteitis deformans in neoplastic disease (Ankle and foot)
0.000 0.997 0.003
M90.66 Osteitis deformans in neoplastic disease (Lower leg)
0.000 0.997 0.003
M90.65 Osteitis deformans in neoplastic disease (Pelvic region and thigh)
0.000 0.997 0.003
M90.64 Osteitis deformans in neoplastic disease (Hand)
0.000 0.997 0.003
M90.63 Osteitis deformans in neoplastic disease (Forearm)
0.000 0.997 0.003
M90.62 Osteitis deformans in neoplastic disease (Upper arm)
0.000 0.997 0.003
M90.60 Osteitis deformans in neoplastic disease (Multiple sites)
0.000 0.997 0.003
C43.1 Malignant melanoma of eyelid, including canthus
0.003 0.997 0.000
Z99.4 Dependence on artificial heart
0.003 0.997 0.000
G60 Hereditary and idiopathic neuropathy
0.000 0.997 0.003
M88.8 Paget's disease of other bones
0.000 0.997 0.003
M87.91 Osteonecrosis, unspecified (Shoulder region)
0.000 0.997 0.003
G60.0 Hereditary motor and sensory neuropathy
0.000 0.997 0.003
A04.4 Other intestinal Escherichia coli infections
0.000 0.997 0.003
C43 Malignant melanoma of skin
0.003 0.997 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.000 0.997 0.003
M90.09 Tuberculosis of bone (Site unspecified)
0.000 0.997 0.003
M90.08 Tuberculosis of bone (Other)
0.000 0.997 0.003
M90.07 Tuberculosis of bone (Ankle and foot)
0.000 0.997 0.003
M90.06 Tuberculosis of bone (Lower leg)
0.000 0.997 0.003
M90.05 Tuberculosis of bone (Pelvic region and thigh)
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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