TreeWAS – Variant ID: rs36221133

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter II Neoplasms	0.999	0.001
Chapter XXI Factors influencing health status and contact with health services	0.999	0.001
Chapter XIV Diseases of the genitourinary system	0.999	0.001
N17-N19 Renal failure	0.997	0.003
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.997	0.003
Z95 Presence of cardiac and vascular implants and grafts	0.997	0.003
N20-N23 Urolithiasis	0.994	0.006
S60-S69 Injuries to the wrist and hand	0.991	0.009
N20 Calculus of kidney and ureter	0.987	0.013
Chapter XII Diseases of the skin and subcutaneous tissue	0.984	0.016
Chapter V Mental and behavioural disorders	0.984	0.016
Z92 Personal history of medical treatment	0.982	0.018
Chapter XI Diseases of the digestive system	0.982	0.018
N19 Unspecified renal failure	0.980	0.020
K20-K31 Diseases of oesophagus, stomach and duodenum	0.980	0.020
S61 Open wound of wrist and hand	0.976	0.024
Z95.8 Presence of other cardiac and vascular implants and grafts	0.975	0.025
K20 Oesophagitis	0.975	0.025
N18 Chronic renal failure	0.973	0.027
Chapter VII Diseases of the eye and adnexa	0.968	0.032
N20.0 Calculus of kidney	0.967	0.033
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.966	0.034
Chapter IV Endocrine, nutritional and metabolic diseases	0.965	0.035
Z95.5 Presence of coronary angioplasty implant and graft	0.962	0.038
Chapter XX External causes of morbidity and mortality	0.962	0.038
S61.0 Open wound of finger(s) without damage to nail	0.959	0.041
C15-C26 Malignant neoplasms of digestive organs	0.955	0.045
Z92.2 Personal history of long-term (current) use of other medicaments	0.950	0.050
Chapter VI Diseases of the nervous system	0.949	0.051
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.946	0.054
Z00-Z13 Persons encountering health services for examination and investigation	0.945	0.055
D37-D48 Neoplasms of uncertain or unknown behaviour	0.945	0.055
L80-L99 Other disorders of the skin and subcutaneous tissue	0.944	0.056
F40-F48 Neurotic, stress-related and somatoform disorders	0.944	0.056
C43-C44 Melanoma and other malignant neoplasms of skin	0.943	0.057
L00-L08 Infections of the skin and subcutaneous tissue	0.936	0.064
G50-G59 Nerve, nerve root and plexus disorders	0.935	0.065
Z95.2 Presence of prosthetic heart valve	0.934	0.066
G56 Mononeuropathies of upper limb	0.927	0.073
E70-E90 Metabolic disorders	0.924	0.076
Z93 Artificial opening status	0.923	0.077
K26 Duodenal ulcer	0.923	0.077
Z92.6 Personal history of chemotherapy for neoplastic disease	0.921	0.079
N18.9 Chronic renal failure, unspecified	0.919	0.081
D10-D36 Benign neoplasms	0.918	0.082
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.917	0.083
G56.0 Carpal tunnel syndrome	0.916	0.084
F30-F39 Mood [affective] disorders	0.914	0.086
Z08 Follow-up examination after treatment for malignant neoplasm	0.913	0.087
Chapter IX Diseases of the circulatory system	0.913	0.087
H53-H54 Visual disturbances and blindness	0.912	0.088
E20-E35 Disorders of other endocrine glands	0.906	0.094
N20.1 Calculus of ureter	0.902	0.098
C44 Other malignant neoplasms of skin	0.901	0.099
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.900	0.100
I30-I52 Other forms of heart disease	0.898	0.102
F41 Other anxiety disorders	0.898	0.102
C20 Malignant neoplasm of rectum	0.887	0.113
Z92.4 Personal history of major surgery, not elsewhere classified	0.887	0.113
L03 Cellulitis	0.884	0.116
M15-M19 Arthrosis	0.881	0.119
L82 Seborrhoeic keratosis	0.881	0.119
D23 Other benign neoplasms of skin	0.879	0.121
F41.2 Mixed anxiety and depressive disorder	0.877	0.123
Z94 Transplanted organ and tissue status	0.875	0.125
C64-C68 Malignant neoplasms of urinary tract	0.875	0.125
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.872	0.128
N23 Unspecified renal colic	0.872	0.128
C44.3 Skin of other and unspecified parts of face	0.869	0.131
M19 Other arthrosis	0.867	0.133
S20-S29 Injuries to the thorax	0.859	0.141
E86 Volume depletion	0.859	0.141
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.857	0.143
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.856	0.144
H53 Visual disturbances	0.856	0.144
Z95.1 Presence of aortocoronary bypass graft	0.854	0.146
Z93.3 Colostomy status	0.854	0.146
K29 Gastritis and duodenitis	0.853	0.147
F31 Bipolar affective disorder	0.849	0.151
H25-H28 Disorders of lens	0.848	0.152
N18.3 Chronic kidney disease, stage 3	0.847	0.153
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.845	0.155
M50-M54 Other dorsopathies	0.845	0.155
E87 Other disorders of fluid, electrolyte and acid-base balance	0.839	0.161
N17 Acute renal failure	0.837	0.163
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.836	0.164
M19.9 Arthrosis, unspecified	0.836	0.164
L92 Granulomatous disorders of skin and subcutaneous tissue	0.834	0.166
M05-M14 Inflammatory polyarthropathies	0.829	0.171
T66-T78 Other and unspecified effects of external causes	0.826	0.174
S61.8 Open wound of other parts of wrist and hand	0.825	0.175
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.820	0.180
N00-N08 Glomerular diseases	0.820	0.180
H26 Other cataract	0.818	0.182
Z13 Special screening examination for other diseases and disorders	0.818	0.182
K22 Other diseases of oesophagus	0.816	0.184
I44 Atrioventricular and left bundle-branch block	0.815	0.185
I47 Paroxysmal tachycardia	0.814	0.186
D23.1 Skin of eyelid, including canthus	0.811	0.189
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.811	0.189
C67 Malignant neoplasm of bladder	0.809	0.191
T84.1 Mechanical complication of internal fixation device of bones of limb	0.808	0.192
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.808	0.192
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.806	0.194
K06 Other disorders of gingiva and edentulous alveolar ridge	0.805	0.195
K29.6 Other gastritis	0.804	0.196
S68 Traumatic amputation of wrist and hand	0.804	0.196
G51 Facial nerve disorders	0.802	0.198
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.802	0.198
C18 Malignant neoplasm of colon	0.801	0.199
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.801	0.199
H26.9 Cataract, unspecified	0.800	0.200
T85 Complications of other internal prosthetic devices, implants and grafts	0.800	0.200
I70-I79 Diseases of arteries, arterioles and capillaries	0.799	0.201
M19.99 Arthrosis, unspecified (Site unspecified)	0.798	0.202
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.798	0.202
G56.2 Lesion of ulnar nerve	0.796	0.204
K29.8 Duodenitis	0.792	0.208
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.791	0.209
W20-W49 Exposure to inanimate mechanical forces	0.790	0.210
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.789	0.211
S70-S79 Injuries to the hip and thigh	0.786	0.214
F00-F09 Organic, including symptomatic, mental disorders	0.786	0.214
D00-D09 In situ neoplasms	0.785	0.215
H53.8 Other visual disturbances	0.785	0.215
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.784	0.216
Z11 Special screening examination for infectious and parasitic diseases	0.784	0.216
K22.1 Ulcer of oesophagus	0.783	0.217
S66 Injury of muscle and tendon at wrist and hand level	0.783	0.217
Z81 Family history of mental and behavioural disorders	0.782	0.217
Z85 Personal history of malignant neoplasm	0.780	0.220
H40-H42 Glaucoma	0.780	0.220
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.779	0.221
Z89 Acquired absence of limb	0.778	0.222
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.778	0.222
E87.1 Hypo-osmolality and hyponatraemia	0.778	0.222
K07 Dentofacial anomalies [including malocclusion]	0.778	0.222
L03.2 Cellulitis of face	0.777	0.223
N18.2 Chronic kidney disease, stage 2	0.775	0.225
I42 Cardiomyopathy	0.773	0.227
I44.0 Atrioventricular block, first degree	0.772	0.228
M19.0 Primary arthrosis of other joints	0.769	0.231
L40-L45 Papulosquamous disorders	0.769	0.231
L81 Other disorders of pigmentation	0.768	0.232
E00-E07 Disorders of thyroid gland	0.767	0.233
C19 Malignant neoplasm of rectosigmoid junction	0.767	0.233
I35 Nonrheumatic aortic valve disorders	0.766	0.234
Z12 Special screening examination for neoplasms	0.766	0.234
E83 Disorders of mineral metabolism	0.764	0.236
F99-F99 Unspecified mental disorder	0.764	0.236
X20-X29 Contact with venomous animals and plants	0.764	0.236
N20.2 Calculus of kidney with calculus of ureter	0.763	0.237
I33 Acute and subacute endocarditis	0.762	0.238
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.762	0.238
Z93.2 Ileostomy status	0.762	0.238
H55-H59 Other disorders of eye and adnexa	0.759	0.241
F43 Reaction to severe stress, and adjustment disorders	0.759	0.241
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.758	0.242
E50-E64 Other nutritional deficiencies	0.755	0.245
G80-G83 Cerebral palsy and other paralytic syndromes	0.755	0.245
Z85.5 Personal history of malignant neoplasm of urinary tract	0.754	0.246
M50 Cervical disk disorders	0.752	0.248
Z94.8 Other transplanted organ and tissue status	0.749	0.251
C67.9 Bladder, unspecified	0.749	0.251
M19.90 Arthrosis, unspecified (Multiple sites)	0.749	0.251
C44.1 Skin of eyelid, including canthus	0.748	0.252
L89 Decubitus ulcer	0.746	0.254
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.745	0.255
T88 Other complications of surgical and medical care, not elsewhere classified	0.743	0.257
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.742	0.258
K04 Diseases of pulp and periapical tissues	0.742	0.258
I50 Heart failure	0.742	0.258
E21.3 Hyperparathyroidism, unspecified	0.740	0.260
V20-V29 Motorcycle rider injured in transport accident	0.740	0.260
Z13.9 Special screening examination, unspecified	0.739	0.260
F33 Recurrent depressive disorder	0.739	0.261
S90-S99 Injuries to the ankle and foot	0.739	0.261
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.738	0.262
Y57 Other and unspecified drugs and medicaments	0.737	0.263
K26.5 Chronic or unspecified with perforation	0.737	0.263
K14 Diseases of tongue	0.737	0.263
N70-N77 Inflammatory diseases of female pelvic organs	0.737	0.263
D18 Haemangioma and lymphangioma, any site	0.736	0.264
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.733	0.267
L08 Other local infections of skin and subcutaneous tissue	0.733	0.267
S50-S59 Injuries to the elbow and forearm	0.733	0.267
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.733	0.267
I71 Aortic aneurysm and dissection	0.731	0.269
D23.7 Skin of lower limb, including hip	0.731	0.269
N99-N99 Other disorders of the genitourinary system	0.730	0.270
D32 Benign neoplasm of meninges	0.730	0.270
L03.3 Cellulitis of trunk	0.730	0.270
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.729	0.271
S40-S49 Injuries to the shoulder and upper arm	0.727	0.273
V10-V19 Pedal cyclist injured in transport accident	0.727	0.273
S64 Injury of nerves at wrist and hand level	0.727	0.273
Z93.5 Cystostomy status	0.726	0.274
H54 Blindness and low vision	0.726	0.274
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.726	0.274
I47.2 Ventricular tachycardia	0.725	0.275
M00-M03 Infectious arthropathies	0.725	0.275
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.725	0.275
N03 Chronic nephritic syndrome	0.725	0.275
Z95.3 Presence of xenogenic heart valve	0.724	0.276
Z04 Examination and observation for other reasons	0.724	0.276
S61.1 Open wound of finger(s) with damage to nail	0.724	0.276
G54 Nerve root and plexus disorders	0.722	0.278
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.722	0.278
N17.9 Acute renal failure, unspecified	0.722	0.278
Z02 Examination and encounter for administrative purposes	0.721	0.279
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.721	0.279
D22 Melanocytic naevi	0.721	0.279
E29 Testicular dysfunction	0.721	0.279
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.720	0.279
H10-H13 Disorders of conjunctiva	0.720	0.280
I60-I69 Cerebrovascular diseases	0.719	0.281
Z30 Contraceptive management	0.717	0.283
Chapter XXII Codes for special purposes	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T79-T79 Certain early complications of trauma	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T15-T19 Effects of foreign body entering through natural orifice	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.716	0.283
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.716	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.283
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.716	0.283
Z31 Procreative management	0.716	0.284
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.715	0.285
S62 Fracture at wrist and hand level	0.715	0.285
Z84 Family history of other conditions	0.715	0.285
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.715	0.285
I05-I09 Chronic rheumatic heart diseases	0.715	0.285
N22 Calculus of urinary tract in diseases classified elsewhere	0.713	0.287
E21.0 Primary hyperparathyroidism	0.712	0.288
Y60-Y69 Misadventures to patients during surgical and medical care	0.712	0.288
L85 Other epidermal thickening	0.712	0.288
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.711	0.289
S22 Fracture of rib(s), sternum and thoracic spine	0.710	0.289
S69 Other and unspecified injuries of wrist and hand	0.710	0.290
S67 Crushing injury of wrist and hand	0.710	0.290
S65 Injury of blood vessels at wrist and hand level	0.710	0.290
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.710	0.290
S60 Superficial injury of wrist and hand	0.710	0.290
D41.4 Bladder	0.709	0.291
M13 Other arthritis	0.709	0.291
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.708	0.292
N20.9 Urinary calculus, unspecified	0.708	0.292
N18.0 End-stage renal disease	0.708	0.292
G51.0 Bell's palsy	0.707	0.293
D27 Benign neoplasm of ovary	0.706	0.294
L10-L14 Bullous disorders	0.706	0.294
F40 Phobic anxiety disorders	0.706	0.294
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.705	0.295
F80-F89 Disorders of psychological development	0.705	0.295
F70-F79 Mental retardation	0.705	0.295
F60-F69 Disorders of adult personality and behaviour	0.705	0.295
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.705	0.295
Z92.9 Personal history of medical treatment, unspecified	0.704	0.296
Z92.8 Personal history of other medical treatment	0.704	0.296
Z92.5 Personal history of rehabilitation measures	0.704	0.296
Z92.0 Personal history of contraception	0.704	0.296
K26.4 Chronic or unspecified with haemorrhage	0.704	0.296
X60-X84 Intentional self-harm	0.704	0.296
E03 Other hypothyroidism	0.704	0.296
F31.9 Bipolar affective disorder, unspecified	0.704	0.296
M45-M49 Spondylopathies	0.703	0.297
D35 Benign neoplasm of other and unspecified endocrine glands	0.703	0.297
Z94.0 Kidney transplant status	0.703	0.297
K28 Gastrojejunal ulcer	0.702	0.298
K23 Disorders of oesophagus in diseases classified elsewhere	0.702	0.298
T78 Adverse effects, not elsewhere classified	0.702	0.298
E80 Disorders of porphyrin and bilirubin metabolism	0.702	0.298
D23.6 Skin of upper limb, including shoulder	0.702	0.298
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.701	0.299
L05 Pilonidal cyst	0.701	0.299
M86-M90 Other osteopathies	0.701	0.299
Z96 Presence of other functional implants	0.700	0.300
S61.7 Multiple open wounds of wrist and hand	0.700	0.300
Chapter VIII Diseases of the ear and mastoid process	0.700	0.300
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.700	0.300
N21 Calculus of lower urinary tract	0.698	0.302
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.698	0.302
D10 Benign neoplasm of mouth and pharynx	0.697	0.302
N18.8 Other chronic renal failure	0.697	0.303
N18.1 Chronic kidney disease, stage 1	0.697	0.303
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.697	0.303
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.696	0.304
N18.4 Chronic kidney disease, stage 4	0.696	0.304
M18 Arthrosis of first carpometacarpal joint	0.695	0.305
H46-H48 Disorders of optic nerve and visual pathways	0.694	0.306
D45 Polycythaemia vera	0.694	0.306
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.694	0.306
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.693	0.306
N10-N16 Renal tubulo-interstitial diseases	0.693	0.307
C15 Malignant neoplasm of oesophagus	0.693	0.307
T87 Complications peculiar to reattachment and amputation	0.693	0.307
T86 Failure and rejection of transplanted organs and tissues	0.693	0.307
T80 Complications following infusion, transfusion and therapeutic injection	0.693	0.307
E40-E46 Malnutrition	0.692	0.308
H53.9 Visual disturbance, unspecified	0.691	0.309
G30-G32 Other degenerative diseases of the nervous system	0.691	0.309
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.690	0.310
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.690	0.310
Y35-Y36 Legal intervention and operations of war	0.690	0.310
Y10-Y34 Event of undetermined intent	0.690	0.310
Y00-Y09 Assault	0.690	0.310
X85-X99 Assault	0.690	0.310
X58-X59 Accidental exposure to other and unspecified factors	0.690	0.310
X50-X57 Overexertion, travel and privation	0.690	0.310
X40-X49 Accidental poisoning by and exposure to noxious substances	0.690	0.310
X30-X39 Exposure to forces of nature	0.690	0.310
X10-X19 Contact with heat and hot substances	0.690	0.310
X00-X09 Exposure to smoke, fire and flames	0.690	0.310
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.690	0.310
W75-W84 Other accidental threats to breathing	0.690	0.310
W65-W74 Accidental drowning and submersion	0.690	0.310
W50-W64 Exposure to animate mechanical forces	0.690	0.310
V98-V99 Other and unspecified transport accidents	0.690	0.310
V95-V97 Air and space transport accidents	0.690	0.310
V90-V94 Water transport accidents	0.690	0.310
V80-V89 Other land transport accidents	0.690	0.310
V70-V79 Bus occupant injured in transport accident	0.690	0.310
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.690	0.310
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.690	0.310
V40-V49 Car occupant injured in transport accident	0.690	0.310
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.690	0.310
V01-V09 Pedestrian injured in transport accident	0.690	0.310
I46 Cardiac arrest	0.689	0.311
D11 Benign neoplasm of major salivary glands	0.689	0.311
W00-W19 Falls	0.689	0.311
K12 Stomatitis and related lesions	0.688	0.312
N25-N29 Other disorders of kidney and ureter	0.687	0.313
S00-S09 Injuries to the head	0.687	0.313
L03.9 Cellulitis, unspecified	0.686	0.314
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.685	0.315
Z60 Problems related to social environment	0.685	0.315
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.685	0.315
I34 Nonrheumatic mitral valve disorders	0.685	0.315
M50.3 Other cervical disk degeneration	0.685	0.315
C26 Malignant neoplasm of other and ill-defined digestive organs	0.684	0.316
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.684	0.316
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.684	0.316
C21 Malignant neoplasm of anus and anal canal	0.684	0.316
C17 Malignant neoplasm of small intestine	0.684	0.316
C23 Malignant neoplasm of gallbladder	0.684	0.316
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.684	0.316
N18.5 Chronic kidney disease, stage 5	0.683	0.317
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.683	0.317
K21 Gastro-oesophageal reflux disease	0.683	0.317
K13 Other diseases of lip and oral mucosa	0.682	0.317
L02 Cutaneous abscess, furuncle and carbuncle	0.682	0.318
K05 Gingivitis and periodontal diseases	0.682	0.318
L03.1 Cellulitis of other parts of limb	0.682	0.318
M80-M85 Disorders of bone density and structure	0.682	0.318
I38 Endocarditis, valve unspecified	0.681	0.319
G70-G73 Diseases of myoneural junction and muscle	0.681	0.319
G00-G09 Inflammatory diseases of the central nervous system	0.681	0.319
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.680	0.319
C16 Malignant neoplasm of stomach	0.680	0.320
C43 Malignant melanoma of skin	0.679	0.320
L50-L54 Urticaria and erythema	0.679	0.321
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.678	0.321
M91-M94 Chondropathies	0.678	0.322
M60-M63 Disorders of muscles	0.678	0.322
Z10 Routine general health check-up of defined subpopulation	0.678	0.322
D46 Myelodysplastic syndromes	0.678	0.322
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.678	0.322
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.678	0.322
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.678	0.322
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.678	0.322
G90-G99 Other disorders of the nervous system	0.677	0.323
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.677	0.323
L95 Vasculitis limited to skin, not elsewhere classified	0.677	0.323
L94 Other localised connective tissue disorders	0.677	0.323
L93 Lupus erythematosus	0.677	0.323
L87 Transepidermal elimination disorders	0.677	0.323
L88 Pyoderma gangrenosum	0.677	0.323
L86 Keratoderma in diseases classified elsewhere	0.677	0.323
L84 Corns and callosities	0.677	0.323
L83 Acanthosis nigricans	0.677	0.323
L80 Vitiligo	0.677	0.323
F48 Other neurotic disorders	0.677	0.323
F45 Somatoform disorders	0.677	0.323
F44 Dissociative [conversion] disorders	0.677	0.323
F42 Obsessive-compulsive disorder	0.677	0.323
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.677	0.323
M11 Other crystal arthropathies	0.677	0.323
E28 Ovarian dysfunction	0.675	0.324
C18.6 Descending colon	0.676	0.324
Z33 Pregnant state, incidental	0.675	0.325
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.674	0.326
L03.8 Cellulitis of other sites	0.673	0.327
L91 Hypertrophic disorders of skin	0.672	0.328
K01 Embedded and impacted teeth	0.672	0.328
L04 Acute lymphadenitis	0.671	0.328
L01 Impetigo	0.671	0.328
L00 Staphylococcal scalded skin syndrome	0.671	0.328
E23 Hypofunction and other disorders of pituitary gland	0.671	0.329
G59 Mononeuropathy in diseases classified elsewhere	0.670	0.330
G58 Other mononeuropathies	0.670	0.330
G53 Cranial nerve disorders in diseases classified elsewhere	0.670	0.330
G52 Disorders of other cranial nerves	0.670	0.330
Y40 Systemic antibiotics	0.670	0.330
T84.2 Mechanical complication of internal fixation device of other bones	0.670	0.330
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.670	0.330
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.670	0.330
C85.1 B-cell lymphoma, unspecified	0.670	0.330
H26.8 Other specified cataract	0.670	0.330
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.669	0.331
Z98 Other postsurgical states	0.669	0.331
I47.9 Paroxysmal tachycardia, unspecified	0.668	0.332
M19.1 Posttraumatic arthrosis of other joints	0.668	0.332
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.666	0.333
S27 Injury of other and unspecified intrathoracic organs	0.666	0.334
Z95.0 Presence of cardiac pacemaker	0.666	0.334
M51 Other intervertebral disk disorders	0.666	0.334
T84.0 Mechanical complication of internal joint prosthesis	0.666	0.334
I33.0 Acute and subacute infective endocarditis	0.665	0.335
G56.9 Mononeuropathy of upper limb, unspecified	0.665	0.335
G56.8 Other mononeuropathies of upper limb	0.665	0.335
G56.4 Causalgia	0.665	0.335
G56.3 Lesion of radial nerve	0.665	0.335
G56.1 Other lesions of median nerve	0.665	0.335
M19.09 Primary arthrosis of other joints (Site unspecified)	0.663	0.337
C44.4 Skin of scalp and neck	0.662	0.337
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.662	0.338
E88 Other metabolic disorders	0.662	0.338
E85 Amyloidosis	0.662	0.338
E84 Cystic fibrosis	0.662	0.338
E79 Disorders of purine and pyrimidine metabolism	0.662	0.338
E77 Disorders of glycoprotein metabolism	0.662	0.338
E76 Disorders of glycosaminoglycan metabolism	0.662	0.338
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.662	0.338
E74 Other disorders of carbohydrate metabolism	0.662	0.338
E73 Lactose intolerance	0.662	0.338
E72 Other disorders of amino-acid metabolism	0.662	0.338
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.662	0.338
E70 Disorders of aromatic amino-acid metabolism	0.662	0.338
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.662	0.338
Z93.9 Artificial opening status, unspecified	0.662	0.338
Z93.8 Other artificial opening status	0.662	0.338
Z93.4 Other artificial openings of gastro-intestinal tract status	0.662	0.338
Z93.0 Tracheostomy status	0.662	0.338
K26.7 Chronic without haemorrhage or perforation	0.662	0.338
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.662	0.338
K26.2 Acute with both haemorrhage and perforation	0.662	0.338
K26.1 Acute with perforation	0.662	0.338
K26.0 Acute with haemorrhage	0.662	0.338
C92 Myeloid leukaemia	0.661	0.338
I50.9 Heart failure, unspecified	0.661	0.339
S80-S89 Injuries to the knee and lower leg	0.660	0.340
F31.0 Bipolar affective disorder, current episode hypomanic	0.660	0.340
Z13.1 Special screening examination for diabetes mellitus	0.659	0.341
K81 Cholecystitis	0.659	0.341
H30-H36 Disorders of choroid and retina	0.659	0.341
K25 Gastric ulcer	0.659	0.341
D33 Benign neoplasm of brain and other parts of central nervous system	0.658	0.341
D31 Benign neoplasm of eye and adnexa	0.658	0.341
D30 Benign neoplasm of urinary organs	0.658	0.341
D29 Benign neoplasm of male genital organs	0.658	0.341
D28 Benign neoplasm of other and unspecified female genital organs	0.658	0.341
D26 Other benign neoplasms of uterus	0.658	0.341
D21 Other benign neoplasms of connective and other soft tissue	0.658	0.341
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.658	0.341
D19 Benign neoplasm of mesothelial tissue	0.658	0.341
D16 Benign neoplasm of bone and articular cartilage	0.658	0.341
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.658	0.341
D14 Benign neoplasm of middle ear and respiratory system	0.658	0.341
D34 Benign neoplasm of thyroid gland	0.658	0.341
E03.9 Hypothyroidism, unspecified	0.658	0.342
H43-H45 Disorders of vitreous body and globe	0.658	0.342
K10 Other diseases of jaws	0.658	0.342
K09 Cysts of oral region, not elsewhere classified	0.658	0.342
K03 Other diseases of hard tissues of teeth	0.658	0.342
K00 Disorders of tooth development and eruption	0.658	0.342
H53.0 Amblyopia ex anopsia	0.656	0.344
N03.9 Unspecified	0.656	0.344
K26.3 Acute without haemorrhage or perforation	0.655	0.344
F38 Other mood [affective] disorders	0.655	0.345
F34 Persistent mood [affective] disorders	0.655	0.345
F30 Manic episode	0.655	0.345
F39 Unspecified mood [affective] disorder	0.655	0.345
I74 Arterial embolism and thrombosis	0.655	0.345
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.654	0.345
I00-I02 Acute rheumatic fever	0.654	0.345
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.654	0.346
Z90 Acquired absence of organs, not elsewhere classified	0.654	0.346
C44.0 Skin of lip	0.653	0.347
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.653	0.347
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.652	0.348
Y57.9 Drug or medicament, unspecified	0.652	0.348
C18.9 Colon, unspecified	0.652	0.348
H53.1 Subjective visual disturbances	0.651	0.349

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations