TreeWAS – Variant ID: rs368331

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I34.0 Mitral (valve) insufficiency	0.902	0.098	0.000
I34 Nonrheumatic mitral valve disorders	0.902	0.098	0.000
I34.1 Mitral (valve) prolapse	0.890	0.110	0.000
I30-I52 Other forms of heart disease	0.869	0.131	0.000
I50 Heart failure	0.861	0.139	0.000
I50.9 Heart failure, unspecified	0.843	0.157	0.000
I42 Cardiomyopathy	0.819	0.181	0.000
I51 Complications and ill-defined descriptions of heart disease	0.817	0.183	0.000
I51.7 Cardiomegaly	0.812	0.188	0.000
I42.0 Dilated cardiomyopathy	0.774	0.226	0.000
I35 Nonrheumatic aortic valve disorders	0.774	0.226	0.000
I50.1 Left ventricular failure	0.773	0.227	0.000
I37 Pulmonary valve disorders	0.759	0.241	0.000
I35.1 Aortic (valve) insufficiency	0.741	0.259	0.000
I42.9 Cardiomyopathy, unspecified	0.696	0.304	0.000
I37.1 Pulmonary valve insufficiency	0.680	0.320	0.000
I36 Nonrheumatic tricuspid valve disorders	0.659	0.341	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.658	0.342	0.000
I35.8 Other aortic valve disorders	0.651	0.349	0.000
I50.0 Congestive heart failure	0.648	0.352	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.647	0.353	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.647	0.353	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.634	0.366	0.000
I30 Acute pericarditis	0.632	0.368	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.630	0.370	0.000
I52 Other heart disorders in diseases classified elsewhere	0.623	0.377	0.000
I48 Atrial fibrillation and flutter	0.623	0.377	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.623	0.377	0.000
I41 Myocarditis in diseases classified elsewhere	0.623	0.377	0.000
I40 Acute myocarditis	0.623	0.377	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.623	0.377	0.000
I32 Pericarditis in diseases classified elsewhere	0.623	0.377	0.000
I42.6 Alcoholic cardiomyopathy	0.612	0.388	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.601	0.399	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.587	0.412	0.000
I42.5 Other restrictive cardiomyopathy	0.587	0.412	0.000
I42.4 Endocardial fibroelastosis	0.587	0.412	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.587	0.412	0.000
I51.5 Myocardial degeneration	0.586	0.414	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.586	0.414	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.586	0.414	0.000
I51.6 Cardiovascular disease, unspecified	0.564	0.436	0.000
I33 Acute and subacute endocarditis	0.563	0.437	0.000
I46 Cardiac arrest	0.562	0.438	0.000
I37.9 Pulmonary valve disorder, unspecified	0.544	0.456	0.000
I37.8 Other pulmonary valve disorders	0.544	0.456	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.544	0.456	0.000
I37.0 Pulmonary valve stenosis	0.544	0.456	0.000
I51.0 Cardiac septal defect, acquired	0.542	0.458	0.000
I30.1 Infective pericarditis	0.520	0.480	0.000
I51.4 Myocarditis, unspecified	0.514	0.486	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.509	0.491	0.000
I42.2 Other hypertrophic cardiomyopathy	0.505	0.495	0.000
I45 Other conduction disorders	0.504	0.496	0.000
I47 Paroxysmal tachycardia	0.491	0.509	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.473	0.527	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.473	0.527	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.473	0.527	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.473	0.527	0.000
I42.8 Other cardiomyopathies	0.470	0.530	0.000
I31 Other diseases of pericardium	0.459	0.541	0.000
I30.8 Other forms of acute pericarditis	0.453	0.547	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.453	0.547	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.447	0.553	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.447	0.553	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.447	0.553	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.447	0.553	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.447	0.553	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.447	0.553	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.447	0.553	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.447	0.553	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.447	0.553	0.000
I40.9 Acute myocarditis, unspecified	0.447	0.553	0.000
I40.8 Other acute myocarditis	0.447	0.553	0.000
I40.1 Isolated myocarditis	0.447	0.553	0.000
I40.0 Infective myocarditis	0.447	0.553	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.447	0.553	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.447	0.553	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.447	0.553	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.447	0.553	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.447	0.553	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.447	0.553	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.447	0.553	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.447	0.553	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.447	0.553	0.000
I48.4 Atypical atrial flutter	0.447	0.553	0.000
I48.3 Typical atrial flutter	0.447	0.553	0.000
I48.2 Chronic atrial fibrillation	0.447	0.553	0.000
I48.1 Persistent atrial fibrillation	0.447	0.553	0.000
I48.0 Paroxysmal atrial fibrillation	0.447	0.553	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.447	0.553	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.447	0.553	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.447	0.553	0.000
I35.9 Aortic valve disorder, unspecified	0.408	0.592	0.000
I33.9 Acute endocarditis, unspecified	0.404	0.596	0.000
I46.1 Sudden cardiac death, so described	0.403	0.597	0.000
I46.0 Cardiac arrest with successful resuscitation	0.399	0.601	0.000
I47.0 Reentry ventricular arrhythmia	0.395	0.605	0.000
I38 Endocarditis, valve unspecified	0.392	0.608	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.381	0.619	0.000
I45.2 Bifascicular block	0.378	0.622	0.000
I45.4 Nonspecific intraventricular block	0.361	0.639	0.000
I45.0 Right fascicular block	0.361	0.639	0.000
I30.9 Acute pericarditis, unspecified	0.358	0.642	0.000
I45.3 Trifascicular block	0.355	0.645	0.000
I45.6 Preexcitation syndrome	0.353	0.647	0.000
I46.9 Cardiac arrest, unspecified	0.347	0.653	0.000
I45.8 Other specified conduction disorders	0.344	0.656	0.000
I33.0 Acute and subacute infective endocarditis	0.343	0.657	0.000
I45.1 Other and unspecified right bundle-branch block	0.342	0.658	0.000
I51.8 Other ill-defined heart diseases	0.341	0.659	0.000
I45.5 Other specified heart block	0.332	0.668	0.000
I31.8 Other specified diseases of pericardium	0.329	0.670	0.000
I31.2 Haemopericardium, not elsewhere classified	0.329	0.670	0.000
I31.1 Chronic constrictive pericarditis	0.329	0.670	0.000
I31.0 Chronic adhesive pericarditis	0.329	0.670	0.000
I45.9 Conduction disorder, unspecified	0.328	0.672	0.000
I47.2 Ventricular tachycardia	0.310	0.690	0.000
I31.9 Disease of pericardium, unspecified	0.284	0.716	0.000
I51.9 Heart disease, unspecified	0.278	0.721	0.001
I31.3 Pericardial effusion (noninflammatory)	0.242	0.758	0.000
S20-S29 Injuries to the thorax	0.200	0.800	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.198	0.802	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.198	0.802	0.000
S80-S89 Injuries to the knee and lower leg	0.191	0.809	0.000
S22.4 Multiple fractures of ribs	0.181	0.819	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.179	0.821	0.000
S80 Superficial injury of lower leg	0.178	0.822	0.000
S10-S19 Injuries to the neck	0.177	0.823	0.000
S27 Injury of other and unspecified intrathoracic organs	0.176	0.824	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.173	0.827	0.000
S22.5 Flail chest	0.172	0.828	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.171	0.829	0.000
S22.40 Multiple fractures of ribs (closed)	0.170	0.830	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.168	0.832	0.000
T93 Sequelae of injuries of lower limb	0.166	0.834	0.000
S80.9 Superficial injury of lower leg, unspecified	0.162	0.838	0.000
S22.3 Fracture of rib	0.162	0.838	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.160	0.840	0.000
S70-S79 Injuries to the hip and thigh	0.159	0.841	0.000
S90-S99 Injuries to the ankle and foot	0.157	0.843	0.000
S22.0 Fracture of thoracic vertebra	0.155	0.845	0.000
S29 Other and unspecified injuries of thorax	0.154	0.846	0.000
S22.50 Flail chest (closed)	0.154	0.846	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.154	0.846	0.000
I35.0 Aortic (valve) stenosis	0.153	0.847	0.000
T93.2 Sequelae of other fractures of lower limb	0.152	0.848	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.152	0.848	0.000
T00-T07 Injuries involving multiple body regions	0.150	0.850	0.000
S22.2 Fracture of sternum	0.150	0.850	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.150	0.850	0.000
S81 Open wound of lower leg	0.148	0.852	0.000
S20 Superficial injury of thorax	0.147	0.853	0.000
T21 Burn and corrosion of trunk	0.147	0.853	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.147	0.853	0.000
S89 Other and unspecified injuries of lower leg	0.146	0.854	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.144	0.856	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.144	0.856	0.000
S26 Injury of heart	0.144	0.856	0.000
S25 Injury of blood vessels of thorax	0.144	0.856	0.000
S24 Injury of nerves and spinal cord at thorax level	0.144	0.856	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.144	0.856	0.000
S21 Open wound of thorax	0.144	0.856	0.000
S22.1 Multiple fractures of thoracic spine	0.143	0.857	0.000
S80.7 Multiple superficial injuries of lower leg	0.142	0.857	0.000
S27.0 Traumatic pneumothorax	0.142	0.858	0.000
T33-T35 Frostbite	0.142	0.858	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.142	0.858	0.000
S22.9 Fracture of bony thorax, part unspecified	0.142	0.858	0.000
S22.8 Fracture of other parts of bony thorax	0.142	0.858	0.000
S27.1 Traumatic haemothorax	0.140	0.860	0.000
S00-S09 Injuries to the head	0.139	0.861	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.138	0.862	0.000
S80.8 Other superficial injuries of lower leg	0.138	0.862	0.000
S86 Injury of muscle and tendon at lower leg level	0.138	0.862	0.000
T23 Burn and corrosion of wrist and hand	0.138	0.862	0.000
S40-S49 Injuries to the shoulder and upper arm	0.138	0.862	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.138	0.862	0.000
S88 Traumatic amputation of lower leg	0.137	0.863	0.000
S87 Crushing injury of lower leg	0.137	0.863	0.000
S85 Injury of blood vessels at lower leg level	0.137	0.863	0.000
S84 Injury of nerves at lower leg level	0.137	0.863	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.137	0.863	0.000
T40.4 Other synthetic narcotics	0.137	0.863	0.000
S27.2 Traumatic heamopneumothorax	0.136	0.863	0.000
S83.2 Tear of meniscus, current	0.136	0.864	0.000
S22.30 Fracture of rib (closed)	0.136	0.864	0.000
S50-S59 Injuries to the elbow and forearm	0.136	0.864	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.135	0.865	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.135	0.865	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.135	0.865	0.000
T93.1 Sequelae of fracture of femur	0.135	0.865	0.000
S13.4 Sprain and strain of cervical spine	0.134	0.866	0.000
S14 Injury of nerves and spinal cord at neck level	0.134	0.866	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.134	0.866	0.000
S12 Fracture of neck	0.134	0.866	0.000
S19 Other and unspecified injuries of neck	0.133	0.866	0.000
S01 Open wound of head	0.133	0.867	0.000
T20 Burn and corrosion of head and neck	0.133	0.867	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.133	0.867	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.132	0.868	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.132	0.868	0.000
S70 Superficial injury of hip and thigh	0.132	0.868	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.131	0.869	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.131	0.869	0.000
T36 Poisoning by systemic antibiotics	0.131	0.869	0.000
S27.3 Other injuries of lung	0.131	0.869	0.000
S22.41 Multiple fractures of ribs (open)	0.130	0.870	0.000
T92 Sequelae of injuries of upper limb	0.130	0.870	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.130	0.870	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.129	0.871	0.000
T25 Burn and corrosion of ankle and foot	0.128	0.872	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.128	0.872	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.128	0.872	0.000
S10 Superficial injury of neck	0.128	0.872	0.000
S90 Superficial injury of ankle and foot	0.127	0.872	0.000
T93.0 Sequelae of open wound of lower limb	0.127	0.873	0.000
S72 Fracture of femur	0.127	0.873	0.000
S17 Crushing injury of neck	0.127	0.873	0.000
S15 Injury of blood vessels at neck level	0.127	0.873	0.000
S11 Open wound of neck	0.127	0.873	0.000
S18 Traumatic amputation at neck level	0.127	0.873	0.000
S16 Injury of muscle and tendon at neck level	0.127	0.873	0.000
S27.9 Injury of unspecified intrathoracic organ	0.126	0.874	0.000
S27.8 Injury of other specified intrathoracic organs	0.126	0.874	0.000
S27.7 Multiple injuries of intrathoracic organs	0.126	0.874	0.000
S27.6 Injury of pleura	0.126	0.874	0.000
S27.5 Injury of thoracic trachea	0.126	0.874	0.000
S27.4 Injury of bronchus	0.126	0.874	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.125	0.875	0.000
T21.0 Burn of unspecified degree of trunk	0.125	0.875	0.000
T95 Sequelae of burns, corrosions and frostbite	0.124	0.876	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.124	0.876	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.124	0.876	0.000
T79-T79 Certain early complications of trauma	0.124	0.876	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.124	0.876	0.000
S22.51 Flail chest (open)	0.124	0.876	0.000
S31 Open wound of abdomen, lower back and pelvis	0.123	0.877	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.123	0.877	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.123	0.877	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.123	0.877	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.123	0.877	0.000
S36 Injury of intra-abdominal organs	0.122	0.878	0.000
S29.9 Unspecified injury of thorax	0.122	0.878	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.121	0.879	0.000
S83.7 Injury to multiple structures of knee	0.120	0.879	0.000
S83.3 Tear of articular cartilage of knee, current	0.120	0.879	0.000
S83.1 Dislocation of knee	0.120	0.879	0.000
S83.0 Dislocation of patella	0.120	0.879	0.000
S81.7 Multiple open wounds of lower leg	0.120	0.880	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.119	0.881	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.119	0.881	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.119	0.881	0.000
S81.9 Open wound of lower leg, part unspecified	0.119	0.881	0.000
S82 Fracture of lower leg, including ankle	0.119	0.881	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.119	0.881	0.000
S01.2 Open wound of nose	0.119	0.881	0.000
T13 Other injuries of lower limb, level unspecified	0.118	0.881	0.000
T39.1 4-Aminophenol derivatives	0.118	0.882	0.000
S05 Injury of eye and orbit	0.118	0.882	0.000
S01.3 Open wound of ear	0.118	0.882	0.000
S01.8 Open wound of other parts of head	0.118	0.882	0.000
T00 Superficial injuries involving multiple body regions	0.117	0.883	0.000
S20.2 Contusion of thorax	0.117	0.883	0.000
S22.31 Fracture of rib (open)	0.116	0.884	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.116	0.884	0.000
S50 Superficial injury of forearm	0.116	0.884	0.000
S22.20 Fracture of sternum (closed)	0.116	0.884	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.115	0.885	0.000
S37 Injury of urinary and pelvic organs	0.115	0.885	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.115	0.885	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.115	0.885	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.115	0.885	0.000
S82.2 Fracture of shaft of tibia	0.115	0.885	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.115	0.885	0.000
T14 Injury of unspecified body region	0.115	0.885	0.000
S82.20 Fracture of shaft of tibia (closed)	0.115	0.885	0.000
S78 Traumatic amputation of hip and thigh	0.114	0.885	0.000
S77 Crushing injury of hip and thigh	0.114	0.885	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.114	0.885	0.000
S75 Injury of blood vessels at hip and thigh level	0.114	0.885	0.000
S74 Injury of nerves at hip and thigh level	0.114	0.885	0.000
T17 Foreign body in respiratory tract	0.114	0.886	0.000
S71 Open wound of hip and thigh	0.114	0.886	0.000
S01.5 Open wound of lip and oral cavity	0.114	0.886	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.114	0.886	0.000
S80.0 Contusion of knee	0.114	0.886	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.114	0.886	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.114	0.886	0.000
S89.9 Unspecified injury of lower leg	0.113	0.886	0.000
I47.1 Supraventricular tachycardia	0.113	0.887	0.000
S92 Fracture of foot, except ankle	0.113	0.887	0.000
S98 Traumatic amputation of ankle and foot	0.113	0.887	0.000
S97 Crushing injury of ankle and foot	0.113	0.887	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.113	0.887	0.000
S95 Injury of blood vessels at ankle and foot level	0.113	0.887	0.000
S94 Injury of nerves at ankle and foot level	0.113	0.887	0.000
S60-S69 Injuries to the wrist and hand	0.113	0.887	0.000
S99 Other and unspecified injuries of ankle and foot	0.112	0.888	0.000
T66-T78 Other and unspecified effects of external causes	0.112	0.888	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.112	0.888	0.000
T98 Sequelae of other and unspecified effects of external causes	0.111	0.888	0.000
T45.2 Vitamins, not elsewhere classified	0.111	0.889	0.000
S42 Fracture of shoulder and upper arm	0.111	0.889	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.111	0.889	0.000
S22.01 Fracture of thoracic vertebra (open)	0.111	0.889	0.000
S29.8 Other specified injuries of thorax	0.111	0.889	0.000
S29.7 Multiple injuries of thorax	0.111	0.889	0.000
S29.0 Injury of muscle and tendon at thorax level	0.111	0.889	0.000
S91 Open wound of ankle and foot	0.111	0.889	0.000
T91 Sequelae of injuries of neck and trunk	0.111	0.889	0.000
T11 Other injuries of upper limb, level unspecified	0.110	0.890	0.000
T09 Other injuries of spine and trunk, level unspecified	0.110	0.890	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.110	0.890	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.110	0.890	0.000
T12 Fracture of lower limb, level unspecified	0.110	0.890	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.110	0.890	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.110	0.890	0.000
T10 Fracture of upper limb, level unspecified	0.110	0.890	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.110	0.890	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.110	0.890	0.000
T08 Fracture of spine, level unspecified	0.110	0.890	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.110	0.890	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.109	0.891	0.000
S13.5 Sprain and strain of thyroid region	0.109	0.891	0.000
S13.3 Multiple dislocations of neck	0.109	0.891	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.109	0.891	0.000
S13.1 Dislocation of cervical vertebra	0.109	0.891	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.109	0.891	0.000
S01.9 Open wound of head, part unspecified	0.109	0.891	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.108	0.892	0.000
T46.1 Calcium-channel blockers	0.108	0.892	0.000
S41 Open wound of shoulder and upper arm	0.108	0.892	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.108	0.892	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.108	0.892	0.000
T05 Traumatic amputations involving multiple body regions	0.108	0.892	0.000
T04 Crushing injuries involving multiple body regions	0.108	0.892	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.108	0.892	0.000
T01 Open wounds involving multiple body regions	0.108	0.892	0.000
T07 Unspecified multiple injuries	0.108	0.892	0.000
T23.3 Burn of third degree of wrist and hand	0.108	0.892	0.000
S22.21 Fracture of sternum (open)	0.107	0.892	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.107	0.893	0.000
T40.8 Lysergide [LSD]	0.107	0.893	0.000
T40.7 Cannabis (derivatives)	0.107	0.893	0.000
T40.5 Cocaine	0.107	0.893	0.000
T40.3 Methadone	0.107	0.893	0.000
T40.1 Heroin	0.107	0.893	0.000
T40.0 Opium	0.107	0.893	0.000
S05.8 Other injuries of eye and orbit	0.107	0.893	0.000
S60 Superficial injury of wrist and hand	0.107	0.893	0.000
T02 Fractures involving multiple body regions	0.106	0.894	0.000
S56 Injury of muscle and tendon at forearm level	0.106	0.894	0.000
T40.6 Other and unspecified narcotics	0.106	0.894	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.106	0.894	0.000
S20.7 Multiple superficial injuries of thorax	0.106	0.894	0.000
S20.4 Other superficial injuries of back wall of thorax	0.106	0.894	0.000
S20.3 Other superficial injuries of front wall of thorax	0.106	0.894	0.000
S20.1 Other and unspecified superficial injuries of breast	0.106	0.894	0.000
S20.0 Contusion of breast	0.106	0.894	0.000
T21.7 Corrosion of third degree of trunk	0.106	0.894	0.000
T21.6 Corrosion of second degree of trunk	0.106	0.894	0.000
T21.5 Corrosion of first degree of trunk	0.106	0.894	0.000
T21.4 Corrosion of unspecified degree of trunk	0.106	0.894	0.000
T21.3 Burn of third degree of trunk	0.106	0.894	0.000
T21.2 Burn of second degree of trunk	0.106	0.894	0.000
T21.1 Burn of first degree of trunk	0.106	0.894	0.000
T19 Foreign body in genito-urinary tract	0.105	0.894	0.000
T15 Foreign body on external eye	0.105	0.894	0.000
T16 Foreign body in ear	0.105	0.894	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.105	0.894	0.000
S89.8 Other specified injuries of lower leg	0.105	0.895	0.000
S89.7 Multiple injuries of lower leg	0.105	0.895	0.000
S89.1 Other specified injuries of lower leg	0.105	0.895	0.000
S89.0 Multiple injuries of lower leg	0.105	0.895	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.104	0.896	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.103	0.896	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.103	0.896	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.103	0.896	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.103	0.896	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.103	0.896	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.103	0.896	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.103	0.896	0.000
S21.9 Open wound of thorax, part unspecified	0.103	0.897	0.000
S21.8 Open wound of other parts of thorax	0.103	0.897	0.000
S21.7 Multiple open wounds of thoracic wall	0.103	0.897	0.000
S21.2 Open wound of back wall of thorax	0.103	0.897	0.000
S21.1 Open wound of front wall of thorax	0.103	0.897	0.000
S21.0 Open wound of breast	0.103	0.897	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.103	0.897	0.000
S23.4 Sprain and strain of ribs and sternum	0.103	0.897	0.000
S23.3 Sprain and strain of thoracic spine	0.103	0.897	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.103	0.897	0.000
S23.1 Dislocation of thoracic vertebra	0.103	0.897	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.103	0.897	0.000
S24.6 Injury of unspecified nerve of thorax	0.103	0.897	0.000
S24.5 Injury of other nerves of thorax	0.103	0.897	0.000
S24.4 Injury of thoracic sympathetic nerves	0.103	0.897	0.000
S24.3 Injury of peripheral nerves of thorax	0.103	0.897	0.000
S24.2 Injury of nerve root of thoracic spine	0.103	0.897	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.103	0.897	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.103	0.897	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.103	0.897	0.000
S25.8 Injury of other blood vessels of thorax	0.103	0.897	0.000
S25.7 Injury of multiple blood vessels of thorax	0.103	0.897	0.000
S25.5 Injury of intercostal blood vessels	0.103	0.897	0.000
S25.4 Injury of pulmonary blood vessels	0.103	0.897	0.000
S25.3 Injury of innominate or subclavian vein	0.103	0.897	0.000
S25.2 Injury of superior vena cava	0.103	0.897	0.000
S25.1 Injury of innominate or subclavian artery	0.103	0.897	0.000
S25.0 Injury of thoracic aorta	0.103	0.897	0.000
S26.9 Injury of heart, unspecified	0.103	0.897	0.000
S26.8 Other injuries of heart	0.103	0.897	0.000
S26.0 Injury of heart with haemopericardium	0.103	0.897	0.000
S28.1 Traumatic amputation of part of thorax	0.103	0.897	0.000
S28.0 Crushed chest	0.103	0.897	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.103	0.897	0.000
S72.3 Fracture of shaft of femur	0.103	0.897	0.000
S90.8 Other superficial injuries of ankle and foot	0.103	0.897	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.103	0.897	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.103	0.897	0.000
S19.9 Unspecified injury of neck	0.103	0.897	0.000
S12.7 Multiple fractures of cervical spine	0.102	0.897	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.102	0.898	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.102	0.898	0.000
T28 Burn and corrosion of other internal organs	0.102	0.898	0.000
T27 Burn and corrosion of respiratory tract	0.102	0.898	0.000
T26 Burn and corrosion confined to eye and adnexa	0.102	0.898	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.102	0.898	0.000
T34 Frostbite with tissue necrosis	0.102	0.898	0.000
T33 Superficial frostbite	0.102	0.898	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.102	0.898	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.102	0.898	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.102	0.898	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.102	0.898	0.000
T36.0 Penicillins	0.102	0.898	0.000
S12.2 Fracture of other specified cervical vertebra	0.101	0.898	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.101	0.899	0.000
T40.2 Other opioids	0.101	0.899	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.101	0.899	0.000
S72.0 Fracture of neck of femur	0.100	0.899	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.100	0.900	0.000
T18 Foreign body in alimentary tract	0.100	0.900	0.000
S79 Other and unspecified injuries of hip and thigh	0.100	0.900	0.000
S60.8 Other superficial injuries of wrist and hand	0.100	0.900	0.000
T20.1 Burn of first degree of head and neck	0.100	0.900	0.000
S08 Traumatic amputation of part of head	0.099	0.900	0.000
S07 Crushing injury of head	0.099	0.900	0.000
S04 Injury of cranial nerves	0.099	0.900	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.099	0.900	0.000
S59 Other and unspecified injuries of forearm	0.099	0.901	0.000
S86.0 Injury of Achilles tendon	0.099	0.901	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.099	0.901	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.099	0.901	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.099	0.901	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.099	0.901	0.000
S72.1 Pertrochanteric fracture	0.099	0.901	0.000
T23.7 Corrosion of third degree of wrist and hand	0.099	0.901	0.000
T23.6 Corrosion of second degree of wrist and hand	0.099	0.901	0.000
T23.5 Corrosion of first degree of wrist and hand	0.099	0.901	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.099	0.901	0.000
T23.2 Burn of second degree of wrist and hand	0.099	0.901	0.000
T23.1 Burn of first degree of wrist and hand	0.099	0.901	0.000
S30.1 Contusion of abdominal wall	0.099	0.901	0.000
S48 Traumatic amputation of shoulder and upper arm	0.099	0.901	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.099	0.901	0.000
S44 Injury of nerves at shoulder and upper arm level	0.099	0.901	0.000
S47 Crushing injury of shoulder and upper arm	0.099	0.901	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.099	0.901	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.099	0.901	0.000
T47.7 Emetics	0.099	0.901	0.000
T47.6 Antidiarrhoeal drugs	0.099	0.901	0.000
T47.5 Digestants	0.099	0.901	0.000
T47.4 Other laxatives	0.099	0.901	0.000
T47.3 Saline and osmotic laxatives	0.099	0.901	0.000
T47.2 Stimulant laxatives	0.099	0.901	0.000
T47.0 Histamine H(2)-receptor antagonists	0.099	0.901	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.099	0.901	0.000
S84.8 Injury of other nerves at lower leg level	0.099	0.901	0.000
S84.7 Injury of multiple nerves at lower leg level	0.099	0.901	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.099	0.901	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.099	0.901	0.000
S84.0 Injury of tibial nerve at lower leg level	0.099	0.901	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.099	0.901	0.000
S85.8 Injury of other blood vessels at lower leg level	0.099	0.901	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.099	0.901	0.000
S85.5 Injury of popliteal vein	0.099	0.901	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.099	0.901	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.099	0.901	0.000
S85.2 Injury of peroneal artery	0.099	0.901	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.099	0.901	0.000
S85.0 Injury of popliteal artery	0.099	0.901	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.099	0.901	0.000
S87.0 Crushing injury of knee	0.099	0.901	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.099	0.901	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.099	0.901	0.000
S88.0 Traumatic amputation at knee level	0.099	0.901	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.099	0.901	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.099	0.901	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.099	0.901	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations