TreeWAS – Variant ID: rs372229746

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	0.890	0.110	0.000
E11 Non-insulin-dependent diabetes mellitus	0.870	0.130	0.000
E11.3 With ophthalmic complications	0.855	0.145	0.000
E10-E14 Diabetes mellitus	0.813	0.187	0.000
E14 Unspecified diabetes mellitus	0.800	0.200	0.000
E14.9 Without complications	0.789	0.211	0.000
E11.7 With multiple complications	0.705	0.295	0.000
E14.3 With ophthalmic complications	0.698	0.302	0.000
E11.8 With unspecified complications	0.695	0.305	0.000
E13 Other specified diabetes mellitus	0.683	0.317	0.000
E14.4 With neurological complications	0.616	0.384	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.602	0.398	0.000
E13.9 Without complications	0.600	0.400	0.000
E11.1 With ketoacidosis	0.598	0.402	0.000
E11.5 With peripheral circulatory complications	0.591	0.409	0.000
E11.6 With other specified complications	0.590	0.410	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.589	0.411	0.000
E14.8 With unspecified complications	0.589	0.411	0.000
E14.1 With ketoacidosis	0.586	0.414	0.000
T39.0 Salicylates	0.586	0.414	0.000
E12 Malnutrition-related diabetes mellitus	0.583	0.417	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.583	0.417	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.581	0.419	0.000
E14.2 Withrenal complications	0.578	0.422	0.000
E14.7 With multiple complications	0.574	0.426	0.000
E14.0 With coma	0.574	0.426	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.572	0.428	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.558	0.442	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.554	0.446	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.530	0.470	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.528	0.472	0.000
T43.6 Psychostimulants with abuse potential	0.510	0.490	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.503	0.497	0.000
E13.8 With unspecified complications	0.490	0.510	0.000
E13.7 With multiple complications	0.490	0.510	0.000
E13.6 With other specified complications	0.490	0.510	0.000
E13.5 With peripheral circulatory complications	0.490	0.510	0.000
E13.4 With neurological complications	0.490	0.510	0.000
E13.2 With renal complications	0.490	0.510	0.000
E13.1 With ketoacidosis	0.490	0.510	0.000
E13.0 With coma	0.490	0.510	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.489	0.511	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.489	0.511	0.000
E14.5 With peripheral circulatory complications	0.486	0.514	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.478	0.522	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.477	0.522	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.476	0.524	0.000
E13.3 With ophthalmic complications	0.468	0.532	0.000
T47.2 Stimulant laxatives	0.468	0.532	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.463	0.537	0.000
E11.2 With renal complications	0.461	0.539	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.458	0.542	0.000
E11.0 With coma	0.452	0.547	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.444	0.556	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.442	0.558	0.000
T36 Poisoning by systemic antibiotics	0.439	0.561	0.000
T46.1 Calcium-channel blockers	0.438	0.562	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.438	0.562	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.433	0.566	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.432	0.568	0.000
T47.4 Other laxatives	0.427	0.573	0.000
T47.6 Antidiarrhoeal drugs	0.425	0.575	0.000
T43.9 Psychotropic drug, unspecified	0.422	0.577	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.422	0.577	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.421	0.579	0.000
E12.9 Without complications	0.418	0.582	0.000
E12.8 With unspecified complications	0.418	0.582	0.000
E12.7 With multiple complications	0.418	0.582	0.000
E12.6 With other specified complications	0.418	0.582	0.000
E12.5 With peripheral circulatory complications	0.418	0.582	0.000
E12.4 With neurological complications	0.418	0.582	0.000
E12.3 With ophthalmic complications	0.418	0.582	0.000
E12.2 With renal complications	0.418	0.582	0.000
E12.1 With ketoacidosis	0.418	0.582	0.000
E12.0 With coma	0.418	0.582	0.000
T39.4 Antirheumatics, not elsewhere classified	0.418	0.582	0.000
T39.2 Pyrazolone derivatives	0.418	0.582	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.416	0.584	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.416	0.584	0.000
T46.7 Peripheral vasodilators	0.416	0.584	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.415	0.585	0.000
E14.6 With other specified complications	0.413	0.586	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.410	0.590	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.407	0.592	0.000
T41.2 Other and unspecified general anaesthetics	0.407	0.593	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.400	0.600	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.400	0.600	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.400	0.600	0.000
T47.7 Emetics	0.400	0.600	0.000
T47.5 Digestants	0.400	0.600	0.000
T47.3 Saline and osmotic laxatives	0.400	0.600	0.000
T47.0 Histamine H(2)-receptor antagonists	0.397	0.603	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.397	0.603	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.397	0.603	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.397	0.603	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.397	0.603	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.397	0.603	0.000
T44.0 Anticholinesterase agents	0.397	0.603	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.395	0.605	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.395	0.605	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.393	0.607	0.000
E10 Insulin-dependent diabetes mellitus	0.385	0.615	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.377	0.622	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.374	0.625	0.000
T50.4 Drugs affecting uric acid metabolism	0.371	0.629	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.367	0.633	0.000
T49.9 Topical agent, unspecified	0.361	0.639	0.000
T49.8 Other topical agents	0.361	0.639	0.000
T49.7 Dental drugs, topically applied	0.361	0.639	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.361	0.639	0.000
T49.5 Ophthalmological drugs and preparations	0.361	0.639	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.361	0.639	0.000
T49.3 Emollients, demulcents and protectants	0.361	0.639	0.000
T49.2 Local astringents and local detergents	0.361	0.639	0.000
T49.1 Antipruritics	0.361	0.639	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.355	0.644	0.000
E10.4 With neurological complications	0.353	0.647	0.000
T41.5 Therapeutic gases	0.350	0.649	0.000
T41.4 Anaesthetic, unspecified	0.350	0.649	0.000
T41.3 Local anaesthetics	0.350	0.649	0.000
T41.1 Intravenous anaesthetics	0.350	0.649	0.000
T41.0 Inhaled anaesthetics	0.350	0.649	0.000
T50.1 Loop [high-ceiling] diuretics	0.350	0.650	0.000
T50.8 Diagnostic agents	0.345	0.655	0.000
T45.0 Antiallergic and antiemetic drugs	0.343	0.656	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.343	0.657	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.343	0.657	0.000
T50.7 Analeptics and opioid receptor antagonists	0.343	0.657	0.000
T50.5 Appetite depressants	0.343	0.657	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.343	0.657	0.000
T50.0 Mineralocorticoids and their antagonists	0.343	0.657	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.339	0.661	0.000
T43.2 Other and unspecified antidepressants	0.337	0.663	0.000
T36.8 Other systemic antibiotics	0.334	0.666	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.330	0.670	0.000
E11.4 With neurological complications	0.327	0.673	0.000
T36.4 Tetracyclines	0.323	0.677	0.000
T42.1 Iminostilbenes	0.323	0.677	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.319	0.681	0.000
T42.3 Barbiturates	0.319	0.681	0.000
T42.2 Succinimides and oxazolidinediones	0.319	0.681	0.000
T36.9 Systemic antibiotic, unspecified	0.315	0.685	0.000
T36.7 Antifungal antibiotics, systemically used	0.315	0.685	0.000
T36.6 Rifamycins	0.315	0.685	0.000
T36.5 Aminoglycosides	0.315	0.685	0.000
T36.3 Macrolides	0.315	0.685	0.000
T36.2 Chloramphenicol group	0.315	0.685	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.315	0.685	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.311	0.689	0.000
T45.8 Other primarily systemic and haematological agents	0.311	0.689	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.311	0.689	0.000
T45.6 Fibrinolysis-affecting drugs	0.311	0.689	0.000
T45.4 Iron and its compounds	0.311	0.689	0.000
T45.3 Enzymes, not elsewhere classified	0.311	0.689	0.000
T38.1 Thyroid hormones and substitutes	0.307	0.693	0.000
T45.2 Vitamins, not elsewhere classified	0.306	0.694	0.000
T42.0 Hydantoin derivatives	0.306	0.694	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.298	0.702	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.296	0.703	0.000
E10.7 With multiple complications	0.295	0.705	0.000
T42.4 Benzodiazepines	0.293	0.707	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.292	0.708	0.000
T37.5 Antiviral drugs	0.292	0.708	0.000
T37.4 Anthelminthics	0.292	0.708	0.000
T37.3 Other antiprotozoal drugs	0.292	0.708	0.000
T37.1 Antimycobacterial drugs	0.292	0.708	0.000
T37.0 Sulphonamides	0.292	0.708	0.000
T45.5 Anticoagulants	0.291	0.709	0.000
E10.5 With peripheral circulatory complications	0.291	0.709	0.000
T36.0 Penicillins	0.291	0.709	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.288	0.712	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.285	0.715	0.000
E10.2 With renal complications	0.283	0.717	0.000
T38.9 Other and unspecified hormone antagonists	0.271	0.729	0.000
T38.7 Androgens and anabolic congeners	0.271	0.729	0.000
T38.5 Other oestrogens and progestogens	0.271	0.729	0.000
T38.4 Oral contraceptives	0.271	0.729	0.000
T38.2 Antithyroid drugs	0.271	0.729	0.000
T38.0 Glucocorticoids and synthetic analogues	0.271	0.729	0.000
E10.6 With other specified complications	0.270	0.730	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.269	0.730	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.269	0.731	0.000
T48.5 Anti-common-cold drugs	0.269	0.731	0.000
T48.4 Expectorants	0.269	0.731	0.000
T48.3 Antitussives	0.269	0.731	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.269	0.731	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.269	0.731	0.000
T48.0 Oxytocic drugs	0.269	0.731	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.260	0.740	0.000
E10.0 With coma	0.250	0.750	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.246	0.753	0.000
E10.8 With unspecified complications	0.242	0.758	0.000
T40.5 Cocaine	0.229	0.771	0.000
T40.1 Heroin	0.220	0.780	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.211	0.788	0.001
E10.3 With ophthalmic complications	0.210	0.790	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.206	0.793	0.000
T40.8 Lysergide [LSD]	0.206	0.793	0.000
T40.7 Cannabis (derivatives)	0.206	0.793	0.000
T40.3 Methadone	0.206	0.793	0.000
T40.0 Opium	0.206	0.793	0.000
T40.6 Other and unspecified narcotics	0.190	0.810	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.189	0.811	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.182	0.818	0.000
T40.4 Other synthetic narcotics	0.180	0.819	0.000
E10.1 With ketoacidosis	0.140	0.860	0.000
E06.3 Autoimmune thyroiditis	0.137	0.863	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.137	0.863	0.000
E06 Thyroiditis	0.136	0.864	0.000
E00-E07 Disorders of thyroid gland	0.133	0.867	0.000
E10.9 Without complications	0.130	0.870	0.000
E06.9 Thyroiditis, unspecified	0.116	0.884	0.000
E04 Other non-toxic goitre	0.106	0.894	0.000
E50-E64 Other nutritional deficiencies	0.103	0.897	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.101	0.899	0.000
E06.1 Subacute thyroiditis	0.101	0.899	0.000
E06.4 Drug-induced thyroiditis	0.098	0.902	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.098	0.902	0.000
E06.0 Acute thyroiditis	0.098	0.902	0.000
E06.5 Other chronic thyroiditis	0.097	0.903	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.095	0.904	0.000
E00 Congenital iodine-deficiency syndrome	0.095	0.904	0.000
E04.2 Non-toxic multinodular goitre	0.095	0.905	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.095	0.905	0.000
E03 Other hypothyroidism	0.092	0.908	0.000
E61 Deficiency of other nutrient elements	0.091	0.909	0.000
E54 Ascorbic acid deficiency	0.088	0.911	0.000
E04.9 Non-toxic goitre, unspecified	0.084	0.916	0.000
E61.1 Iron deficiency	0.083	0.917	0.000
E03.8 Other specified hypothyroidism	0.082	0.918	0.000
E40-E46 Malnutrition	0.081	0.919	0.000
E04.0 Non-toxic diffuse goitre	0.078	0.922	0.000
E04.8 Other specified non-toxic goitre	0.076	0.924	0.000
E07 Other disorders of thyroid	0.076	0.924	0.000
E56 Other vitamin deficiencies	0.076	0.924	0.000
E58 Dietary calcium deficiency	0.074	0.926	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.074	0.926	0.000
E63 Other nutritional deficiencies	0.074	0.926	0.000
E50 Vitamin A deficiency	0.074	0.926	0.000
E60 Dietary zinc deficiency	0.074	0.926	0.000
E59 Dietary selenium deficiency	0.074	0.926	0.000
E52 Niacin deficiency [pellagra]	0.074	0.926	0.000
E51 Thiamine deficiency	0.072	0.928	0.000
E03.1 Congenital hypothyroidism without goitre	0.069	0.931	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.069	0.931	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.069	0.931	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.069	0.931	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.069	0.931	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.069	0.931	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.069	0.931	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.069	0.931	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.069	0.931	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.068	0.931	0.000
E15 Nondiabetic hypoglycaemic coma	0.068	0.932	0.000
E65-E68 Obesity and other hyperalimentation	0.067	0.933	0.000
E03.5 Myxoedema coma	0.066	0.934	0.000
E03.4 Atrophy of thyroid (acquired)	0.066	0.934	0.000
E03.3 Postinfectious hypothyroidism	0.066	0.934	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.066	0.934	0.000
E61.9 Deficiency of nutrient element, unspecified	0.065	0.934	0.000
E61.8 Deficiency of other specified nutrient elements	0.065	0.934	0.000
E61.7 Deficiency of multiple nutrient elements	0.065	0.934	0.000
E61.6 Vanadium deficiency	0.065	0.934	0.000
E61.5 Molybdenum deficiency	0.065	0.934	0.000
E61.4 Chromium deficiency	0.065	0.934	0.000
E61.3 Manganese deficiency	0.065	0.934	0.000
E61.0 Copper deficiency	0.065	0.934	0.000
E16 Other disorders of pancreatic internal secretion	0.065	0.935	0.000
E61.2 Magnesium deficiency	0.065	0.935	0.000
E16.1 Other hypoglycaemia	0.060	0.940	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.058	0.942	0.000
E45 Retarded development following protein-energy malnutrition	0.058	0.942	0.000
E43 Unspecified severe protein-energy malnutrition	0.058	0.942	0.000
E42 Marasmic kwashiorkor	0.058	0.942	0.000
E41 Nutritional marasmus	0.058	0.942	0.000
E40 Kwashiorkor	0.058	0.942	0.000
E56.1 Deficiency of vitamin K	0.057	0.943	0.000
E07.1 Dyshormogenetic goitre	0.055	0.945	0.000
E07.0 Hypersecretion of calcitonin	0.055	0.945	0.000
E56.9 Vitamin deficiency, unspecified	0.054	0.945	0.000
E56.8 Deficiency of other vitamins	0.054	0.945	0.000
E56.0 Deficiency of vitamin E	0.054	0.945	0.000
T39.1 4-Aminophenol derivatives	0.053	0.946	0.000
E50.9 Vitamin A deficiency, unspecified	0.053	0.947	0.000
E50.8 Other manifestations of vitamin A deficiency	0.053	0.947	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.053	0.947	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.053	0.947	0.000
E50.5 Vitamin A deficiency with night blindness	0.053	0.947	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.053	0.947	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.053	0.947	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.053	0.947	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.053	0.947	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.053	0.947	0.000
E63.9 Nutritional deficiency, unspecified	0.053	0.947	0.000
E63.8 Other specified nutritional deficiencies	0.053	0.947	0.000
E63.1 Imbalance of constituents of food intake	0.053	0.947	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.053	0.947	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.053	0.947	0.000
E64.8 Sequelae of other nutritional deficiencies	0.053	0.947	0.000
E64.3 Sequelae of rickets	0.053	0.947	0.000
E64.2 Sequelae of vitamin C deficiency	0.053	0.947	0.000
E64.1 Sequelae of vitamin A deficiency	0.053	0.947	0.000
E64.0 Sequelae of protein-energy malnutrition	0.053	0.947	0.000
T40.2 Other opioids	0.053	0.947	0.000
E51.9 Thiamine deficiency, unspecified	0.052	0.948	0.000
E51.8 Other manifestations of thiamine deficiency	0.052	0.948	0.000
E51.1 Beriberi	0.052	0.948	0.000
E07.8 Other specified disorders of thyroid	0.051	0.949	0.000
E51.2 Wernicke's encephalopathy	0.050	0.950	0.000
E67 Other hyperalimentation	0.048	0.952	0.000
E68 Sequelae of hyperalimentation	0.048	0.952	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.047	0.953	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.047	0.953	0.000
E16.4 Abnormal secretion of gastrin	0.047	0.953	0.000
E16.3 Increased secretion of glucagon	0.047	0.953	0.000
E55 Vitamin D deficiency	0.046	0.953	0.000
E65 Localised adiposity	0.043	0.957	0.000
E07.9 Disorder of thyroid, unspecified	0.042	0.957	0.000
E44.1 Mild protein-energy malnutrition	0.042	0.958	0.000
E44.0 Moderate protein-energy malnutrition	0.042	0.958	0.000
E46 Unspecified protein-energy malnutrition	0.041	0.959	0.000
E53 Deficiency of other B group vitamins	0.040	0.960	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.037	0.963	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.035	0.965	0.000
E04.1 Non-toxic single thyroid nodule	0.035	0.965	0.000
E67.8 Other specified hyperalimentation	0.035	0.965	0.000
E67.3 Hypervitaminosis D	0.035	0.965	0.000
E67.2 Megavitamin-B6 syndrome	0.035	0.965	0.000
E67.1 Hypercarotenaemia	0.035	0.965	0.000
E67.0 Hypervitaminosis A	0.035	0.965	0.000
E55.0 Rickets, active	0.033	0.966	0.000
E53.1 Pyridoxine deficiency	0.029	0.971	0.000
E53.0 Riboflavin deficiency	0.029	0.971	0.000
N62 Hypertrophy of breast	0.029	0.971	0.000
E66 Obesity	0.027	0.973	0.000
E05.8 Other thyrotoxicosis	0.026	0.974	0.000
E05.5 Thyroid crisis or storm	0.026	0.974	0.000
E05.4 Thyrotoxicosis factitia	0.026	0.974	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.026	0.974	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.026	0.974	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.025	0.975	0.000
E53.9 Vitamin B deficiency, unspecified	0.024	0.975	0.000
E16.2 Hypoglycaemia, unspecified	0.024	0.976	0.000
E66.8 Other obesity	0.020	0.980	0.000
E66.1 Drug-induced obesity	0.020	0.980	0.000
E66.0 Obesity due to excess calories	0.019	0.980	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.019	0.981	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.014	0.986	0.000
E83.1 Disorders of iron metabolism	0.013	0.987	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.011	0.989	0.000
Q79.6 Ehlers-Danlos syndrome	0.011	0.989	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.010	0.990	0.000
G62.9 Polyneuropathy, unspecified	0.010	0.990	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.009	0.991	0.000
E20-E35 Disorders of other endocrine glands	0.009	0.991	0.000
Q79.1 Other congenital malformations of diaphragm	0.009	0.991	0.000
G61.0 Guillain-Barre syndrome	0.008	0.992	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.008	0.992	0.000
Q79.5 Other congenital malformations of abdominal wall	0.008	0.992	0.000
Q79.4 Prune belly syndrome	0.008	0.992	0.000
Q79.3 Gastroschisis	0.008	0.992	0.000
Q79.2 Exomphalos	0.008	0.992	0.000
Q79.0 Congenital diaphragmatic hernia	0.008	0.992	0.000
Q68 Other congenital musculoskeletal deformities	0.008	0.992	0.000
E20 Hypoparathyroidism	0.008	0.992	0.000
G62 Other polyneuropathies	0.008	0.992	0.000
Q76 Congenital malformations of spine and bony thorax	0.007	0.992	0.000
E53.8 Deficiency of other specified B group vitamins	0.007	0.993	0.000
G61 Inflammatory polyneuropathy	0.007	0.993	0.000
E70-E90 Metabolic disorders	0.007	0.993	0.000
E26 Hyperaldosteronism	0.007	0.993	0.000
E83 Disorders of mineral metabolism	0.007	0.993	0.000
Q70 Syndactyly	0.007	0.993	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.007	0.993	0.000
Q65 Congenital deformities of hip	0.007	0.993	0.000
E20.9 Hypoparathyroidism, unspecified	0.007	0.993	0.000
Q61.3 Polycystic kidney, unspecified	0.007	0.993	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.007	0.993	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.007	0.993	0.000
E25 Adrenogenital disorders	0.007	0.993	0.000
E55.9 Vitamin D deficiency, unspecified	0.006	0.993	0.001
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.007	0.993	0.000
Q74 Other congenital malformations of limb(s)	0.007	0.993	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.006	0.993	0.000
E32 Diseases of thymus	0.006	0.993	0.000
E30 Disorders of puberty, not elsewhere classified	0.006	0.993	0.000
Q75 Other congenital malformations of skull and face bones	0.006	0.993	0.000
Q73 Reduction defects of unspecified limb	0.006	0.993	0.000
Q72 Reduction defects of lower limb	0.006	0.993	0.000
Q71 Reduction defects of upper limb	0.006	0.993	0.000
Q69 Polydactyly	0.006	0.993	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.006	0.993	0.000
G61.8 Other inflammatory polyneuropathies	0.006	0.994	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.006	0.994	0.000
E27 Other disorders of adrenal gland	0.006	0.994	0.000
E27.9 Disorder of adrenal gland, unspecified	0.006	0.994	0.000
E31 Polyglandular dysfunction	0.006	0.994	0.000
E75.5 Other lipid storage disorders	0.006	0.994	0.000
Q76.5 Cervical rib	0.006	0.994	0.000
Q78 Other osteochondrodysplasias	0.006	0.994	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.006	0.994	0.000
E26.0 Primary hyperaldosteronism	0.006	0.994	0.000
Q70.3 Webbed toes	0.006	0.994	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.006	0.994	0.000
Q68.4 Congenital bowing of tibia and fibula	0.006	0.994	0.000
Q68.3 Congenital bowing of femur	0.006	0.994	0.000
Q68.2 Congenital deformity of knee	0.006	0.994	0.000
Q68.1 Congenital deformity of hand	0.006	0.994	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.006	0.994	0.000
E20.8 Other hypoparathyroidism	0.006	0.994	0.000
E20.1 Pseudohypoparathyroidism	0.006	0.994	0.000
E20.0 Idiopathic hypoparathyroidism	0.006	0.994	0.000
G62.0 Drug-induced polyneuropathy	0.006	0.994	0.000
E72 Other disorders of amino-acid metabolism	0.006	0.994	0.000
E34 Other endocrine disorders	0.006	0.994	0.000
E84 Cystic fibrosis	0.006	0.994	0.000
G62.2 Polyneuropathy due to other toxic agents	0.006	0.994	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.006	0.994	0.000
Q76.8 Other congenital malformations of bony thorax	0.006	0.994	0.000
Q76.7 Congenital malformation of sternum	0.006	0.994	0.000
Q76.6 Other congenital malformations of ribs	0.006	0.994	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.006	0.994	0.000
Q76.2 Congenital spondylolisthesis	0.006	0.994	0.000
G62.1 Alcoholic polyneuropathy	0.006	0.994	0.000
Q76.1 Klippel-Feil syndrome	0.005	0.994	0.000
G61.1 Serum neuropathy	0.005	0.994	0.000
E79 Disorders of purine and pyrimidine metabolism	0.006	0.994	0.000
E26.9 Hyperaldosteronism, unspecified	0.005	0.994	0.000
E77 Disorders of glycoprotein metabolism	0.005	0.994	0.000
E76 Disorders of glycosaminoglycan metabolism	0.005	0.994	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.005	0.994	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.005	0.994	0.000
Q77.4 Achondroplasia	0.005	0.994	0.000
E27.2 Addisonian crisis	0.005	0.994	0.000
E70 Disorders of aromatic amino-acid metabolism	0.005	0.994	0.000
Q61 Cystic kidney disease	0.005	0.995	0.000
E26.8 Other hyperaldosteronism	0.005	0.995	0.000
E26.1 Secondary hyperaldosteronism	0.005	0.995	0.000
E29 Testicular dysfunction	0.005	0.995	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.005	0.995	0.000
E83.8 Other disorders of mineral metabolism	0.005	0.995	0.000
E83.2 Disorders of zinc metabolism	0.005	0.995	0.000
E83.0 Disorders of copper metabolism	0.005	0.995	0.000
Q70.9 Syndactyly, unspecified	0.005	0.995	0.000
Q70.4 Polysyndactyly	0.005	0.995	0.000
Q70.2 Fused toes	0.005	0.995	0.000
Q70.1 Webbed fingers	0.005	0.995	0.000
Q70.0 Fused fingers	0.005	0.995	0.000
Q66 Congenital deformities of feet	0.005	0.995	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.005	0.995	0.000
Q65.9 Congenital deformity of hip, unspecified	0.005	0.995	0.000
Q65.6 Unstable hip	0.005	0.995	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.005	0.995	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.005	0.995	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.005	0.995	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.005	0.995	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.005	0.995	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.005	0.995	0.000
E85 Amyloidosis	0.005	0.995	0.000
Q82 Other congenital malformations of skin	0.005	0.995	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.005	0.995	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.005	0.995	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.005	0.995	0.000
Q77.6 Chondroectodermal dysplasia	0.005	0.995	0.000
Q77.5 Diastrophic dysplasia	0.005	0.995	0.000
Q77.3 Chondrodysplasia punctata	0.005	0.995	0.000
Q77.2 Short rib syndrome	0.005	0.995	0.000
Q77.1 Thanatophoric short stature	0.005	0.995	0.000
Q77.0 Achondrogenesis	0.005	0.995	0.000
G64 Other disorders of peripheral nervous system	0.005	0.995	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.005	0.995	0.000
E25.9 Adrenogenital disorder, unspecified	0.005	0.995	0.000
E25.8 Other adrenogenital disorders	0.005	0.995	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.005	0.995	0.000
Q82.8 Other specified congenital malformations of skin	0.005	0.995	0.000
E75.6 Lipid storage disorder, unspecified	0.005	0.995	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.005	0.995	0.000
E75.3 Sphingolipidosis, unspecified	0.005	0.995	0.000
E75.2 Other sphingolipidosis	0.005	0.995	0.000
E75.1 Other gangliosidosis	0.005	0.995	0.000
E75.0 GM2 gangliosidosis	0.005	0.995	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.005	0.995	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.005	0.995	0.000
Q74.3 Arthrogryposis multiplex congenita	0.005	0.995	0.000
Q69.9 Polydactyly, unspecified	0.005	0.995	0.000
Q69.2 Accessory toe(s)	0.005	0.995	0.000
Q69.1 Accessory thumb(s)	0.005	0.995	0.000
Q69.0 Accessory finger(s)	0.005	0.995	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.005	0.995	0.000
Q71.8 Other reduction defects of upper limb(s)	0.005	0.995	0.000
Q71.6 Lobster-claw hand	0.005	0.995	0.000
Q71.5 Longitudinal reduction defect of ulna	0.005	0.995	0.000
Q71.4 Longitudinal reduction defect of radius	0.005	0.995	0.000
Q71.3 Congenital absence of hand and finger(s)	0.005	0.995	0.000
Q71.2 Congenital absence of both forearm and hand	0.005	0.995	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.005	0.995	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.005	0.995	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.005	0.995	0.000
Q72.8 Other reduction defects of lower limb(s)	0.005	0.995	0.000
Q72.7 Split foot	0.005	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations