TreeWAS – Variant ID: rs37603

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
E66.9 Obesity, unspecified	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
E65-E68 Obesity and other hyperalimentation	1.000	0.000
Chapter II Neoplasms	1.000	0.000
E66 Obesity	1.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.996	0.004
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.995	0.005
C15-C26 Malignant neoplasms of digestive organs	0.987	0.013
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.982	0.018
Chapter VIII Diseases of the ear and mastoid process	0.981	0.019
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.980	0.020
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.976	0.024
H65-H75 Diseases of middle ear and mastoid	0.964	0.036
D69 Purpura and other haemorrhagic conditions	0.958	0.042
D37-D48 Neoplasms of uncertain or unknown behaviour	0.957	0.043
M70-M79 Other soft tissue disorders	0.956	0.044
Chapter XII Diseases of the skin and subcutaneous tissue	0.955	0.045
L00-L08 Infections of the skin and subcutaneous tissue	0.948	0.052
L02 Cutaneous abscess, furuncle and carbuncle	0.947	0.053
S20-S29 Injuries to the thorax	0.945	0.055
D50-D53 Nutritional anaemias	0.942	0.058
E70-E90 Metabolic disorders	0.934	0.066
M72 Fibroblastic disorders	0.931	0.069
D00-D09 In situ neoplasms	0.928	0.072
D69.6 Thrombocytopenia, unspecified	0.921	0.079
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.920	0.080
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.919	0.081
T90 Sequelae of injuries of head	0.918	0.082
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.916	0.084
S90-S99 Injuries to the ankle and foot	0.911	0.089
C18 Malignant neoplasm of colon	0.911	0.089
H60-H62 Diseases of external ear	0.908	0.092
T93 Sequelae of injuries of lower limb	0.907	0.093
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.906	0.094
H74 Other disorders of middle ear and mastoid	0.897	0.103
E20-E35 Disorders of other endocrine glands	0.887	0.113
C20 Malignant neoplasm of rectum	0.886	0.114
C18.7 Sigmoid colon	0.884	0.116
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.882	0.118
E50-E64 Other nutritional deficiencies	0.879	0.121
H71 Cholesteatoma of middle ear	0.878	0.122
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.876	0.124
T92 Sequelae of injuries of upper limb	0.873	0.127
T91 Sequelae of injuries of neck and trunk	0.871	0.129
E87 Other disorders of fluid, electrolyte and acid-base balance	0.871	0.129
D50 Iron deficiency anaemia	0.871	0.129
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.869	0.131
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.866	0.134
S00-S09 Injuries to the head	0.865	0.135
H73 Other disorders of tympanic membrane	0.864	0.136
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.863	0.137
M75 Shoulder lesions	0.862	0.138
D80-D89 Certain disorders involving the immune mechanism	0.857	0.143
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.857	0.143
H61 Other disorders of external ear	0.855	0.145
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.853	0.147
S22 Fracture of rib(s), sternum and thoracic spine	0.851	0.149
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.851	0.149
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.850	0.150
E00-E07 Disorders of thyroid gland	0.849	0.151
T79-T79 Certain early complications of trauma	0.848	0.152
T93.2 Sequelae of other fractures of lower limb	0.844	0.156
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.841	0.159
Chapter V Mental and behavioural disorders	0.840	0.160
C90 Multiple myeloma and malignant plasma cell neoplasms	0.836	0.164
Chapter XXI Factors influencing health status and contact with health services	0.833	0.167
M45-M49 Spondylopathies	0.833	0.167
C16 Malignant neoplasm of stomach	0.833	0.167
D50.9 Iron deficiency anaemia, unspecified	0.829	0.171
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.829	0.171
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.827	0.172
S10-S19 Injuries to the neck	0.826	0.174
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.825	0.175
C25 Malignant neoplasm of pancreas	0.824	0.176
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.823	0.177
H74.3 Other acquired abnormalities of ear ossicles	0.819	0.181
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.817	0.183
S91 Open wound of ankle and foot	0.817	0.183
M75.0 Adhesive capsulitis of shoulder	0.815	0.185
M91-M94 Chondropathies	0.814	0.186
C83 Diffuse non-Hodgkin's lymphoma	0.813	0.187
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.812	0.188
E78.5 Hyperlipidaemia, unspecified	0.811	0.189
T90.2 Sequelae of fracture of skull and facial bones	0.807	0.193
C51-C58 Malignant neoplasms of female genital organs	0.807	0.193
E10-E14 Diabetes mellitus	0.807	0.193
D51 Vitamin B12 deficiency anaemia	0.804	0.196
D68 Other coagulation defects	0.804	0.196
C92 Myeloid leukaemia	0.802	0.198
D69.5 Secondary thrombocytopenia	0.802	0.198
S21 Open wound of thorax	0.795	0.205
H61.8 Other specified disorders of external ear	0.795	0.205
H73.8 Other specified disorders of tympanic membrane	0.792	0.208
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.790	0.210
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.787	0.213
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.786	0.214
Z70-Z76 Persons encountering health services in other circumstances	0.785	0.215
D04 Carcinoma in situ of skin	0.785	0.215
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.785	0.215
E89.0 Postprocedural hypothyroidism	0.783	0.217
H69 Other disorders of Eustachian tube	0.783	0.217
D46 Myelodysplastic syndromes	0.781	0.219
E04 Other non-toxic goitre	0.777	0.222
D05 Carcinoma in situ of breast	0.777	0.223
E23 Hypofunction and other disorders of pituitary gland	0.776	0.224
T90.9 Sequelae of unspecified injury of head	0.775	0.225
C18.0 Caecum	0.773	0.227
E66.0 Obesity due to excess calories	0.770	0.230
C73 Malignant neoplasm of thyroid gland	0.770	0.230
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.770	0.230
E87.1 Hypo-osmolality and hyponatraemia	0.768	0.232
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.767	0.232
H70 Mastoiditis and related conditions	0.766	0.234
M75.1 Rotator cuff syndrome	0.765	0.235
D41.4 Bladder	0.764	0.236
M00-M03 Infectious arthropathies	0.763	0.236
D69.3 Idiopathic thrombocytopenic purpura	0.762	0.238
T98 Sequelae of other and unspecified effects of external causes	0.760	0.240
C32 Malignant neoplasm of larynx	0.759	0.241
E87.2 Acidosis	0.757	0.243
D86 Sarcoidosis	0.754	0.246
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.753	0.247
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.753	0.247
E55 Vitamin D deficiency	0.750	0.250
D66 Hereditary factor VIII deficiency	0.748	0.252
D70-D77 Other diseases of blood and blood-forming organs	0.747	0.253
T91.8 Sequelae of other specified injuries of neck and trunk	0.746	0.254
T20-T25 Burns and corrosions of external body surface, specified by site	0.746	0.254
M65-M68 Disorders of synovium and tendon	0.746	0.254
S27 Injury of other and unspecified intrathoracic organs	0.745	0.255
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.745	0.255
E04.1 Non-toxic single thyroid nodule	0.744	0.256
D45 Polycythaemia vera	0.743	0.257
Z33 Pregnant state, incidental	0.742	0.258
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.741	0.259
T79 Certain early complications of trauma, not elsewhere classified	0.740	0.260
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.738	0.262
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.738	0.262
D03 Melanoma in situ	0.737	0.263
F00-F09 Organic, including symptomatic, mental disorders	0.737	0.263
S70-S79 Injuries to the hip and thigh	0.736	0.263
E87.0 Hyperosmolality and hypernatraemia	0.735	0.265
M60-M63 Disorders of muscles	0.733	0.267
D09 Carcinoma in situ of other and unspecified sites	0.733	0.267
M48 Other spondylopathies	0.730	0.270
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.730	0.270
S91.3 Open wound of other parts of foot	0.728	0.272
C23 Malignant neoplasm of gallbladder	0.727	0.273
E11 Non-insulin-dependent diabetes mellitus	0.726	0.274
C54 Malignant neoplasm of corpus uteri	0.725	0.275
M76 Enthesopathies of lower limb, excluding foot	0.724	0.276
H74.4 Polyp of middle ear	0.723	0.277
T92.2 Sequelae of fracture at wrist and hand level	0.718	0.282
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.718	0.282
S01 Open wound of head	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
E67 Other hyperalimentation	0.717	0.283
E68 Sequelae of hyperalimentation	0.717	0.283
E65 Localised adiposity	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
E66.2 Extreme obesity with alveolar hypoventilation	0.717	0.283
E66.1 Drug-induced obesity	0.717	0.283
T92.1 Sequelae of fracture of arm	0.715	0.285
T95 Sequelae of burns, corrosions and frostbite	0.713	0.287
T94 Sequelae of injuries involving multiple and unspecified body regions	0.713	0.287
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.713	0.287
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.713	0.287
C71 Malignant neoplasm of brain	0.713	0.287
E24 Cushing's syndrome	0.712	0.288
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.711	0.289
E80 Disorders of porphyrin and bilirubin metabolism	0.711	0.289
C83.3 Large cell (diffuse)	0.710	0.290
Q20-Q28 Congenital malformations of the circulatory system	0.710	0.290
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.710	0.290
L05 Pilonidal cyst	0.710	0.290
Z75 Problems related to medical facilities and other health care	0.709	0.291
M70 Soft tissue disorders related to use, overuse and pressure	0.708	0.291
L20-L30 Dermatitis and eczema	0.708	0.291
C21 Malignant neoplasm of anus and anal canal	0.707	0.293
C17 Malignant neoplasm of small intestine	0.707	0.293
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.707	0.293
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.706	0.293
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.705	0.295
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.704	0.296
C95 Leukaemia of unspecified cell type	0.704	0.296
C94 Other leukaemias of specified cell type	0.704	0.296
C93 Monocytic leukaemia	0.704	0.296
C88 Malignant immunoproliferative diseases	0.704	0.296
C86 Other specified types of T/NK-cell lymphoma	0.704	0.296
C84 Peripheral and cutaneous T-cell lymphomas	0.704	0.296
C69 Malignant neoplasm of eye and adnexa	0.704	0.296
D67 Hereditary factor IX deficiency	0.703	0.297
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.703	0.297
S40-S49 Injuries to the shoulder and upper arm	0.702	0.298
T88 Other complications of surgical and medical care, not elsewhere classified	0.701	0.299
S22.4 Multiple fractures of ribs	0.700	0.300
C16.9 Stomach, unspecified	0.700	0.300
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.696	0.304
F30-F39 Mood [affective] disorders	0.696	0.304
T58 Toxic effect of carbon monoxide	0.695	0.305
E40-E46 Malnutrition	0.694	0.305
D68.5 Primary Thrombophilia	0.692	0.308
S80-S89 Injuries to the knee and lower leg	0.692	0.308
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.691	0.309
H68 Eustachian salpingitis and obstruction	0.691	0.309
H67 Otitis media in diseases classified elsewhere	0.691	0.309
E53 Deficiency of other B group vitamins	0.690	0.310
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.689	0.311
D50.8 Other iron deficiency anaemias	0.689	0.311
S05 Injury of eye and orbit	0.689	0.311
S21.1 Open wound of front wall of thorax	0.689	0.311
D05.1 Intraductal carcinoma in situ	0.689	0.311
D69.9 Haemorrhagic condition, unspecified	0.687	0.313
D69.8 Other specified haemorrhagic conditions	0.687	0.313
D69.4 Other primary thrombocytopenia	0.687	0.313
D69.2 Other nonthrombocytopenic purpura	0.687	0.313
D69.1 Qualitative platelet defects	0.687	0.313
D69.0 Allergic purpura	0.687	0.313
C25.9 Pancreas, unspecified	0.687	0.313
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.686	0.314
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.686	0.314
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.686	0.314
E87.6 Hypokalaemia	0.686	0.314
M73 Soft tissue disorders in diseases classified elsewhere	0.685	0.314
C90.0 Multiple myeloma	0.685	0.315
L10-L14 Bullous disorders	0.685	0.315
M80-M85 Disorders of bone density and structure	0.685	0.315
S92 Fracture of foot, except ankle	0.684	0.316
T90.5 Sequelae of intracranial injury	0.683	0.317
S90 Superficial injury of ankle and foot	0.683	0.317
T86 Failure and rejection of transplanted organs and tissues	0.683	0.317
D55-D59 Haemolytic anaemias	0.682	0.318
H66 Suppurative and unspecified otitis media	0.682	0.318
E78.1 Pure hyperglyceridaemia	0.681	0.319
C32.1 Supraglottis	0.681	0.319
L04 Acute lymphadenitis	0.680	0.320
L01 Impetigo	0.680	0.320
L00 Staphylococcal scalded skin syndrome	0.680	0.320
S20 Superficial injury of thorax	0.679	0.321
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.679	0.321
L50-L54 Urticaria and erythema	0.678	0.322
T91.9 Sequelae of unspecified injury of neck and trunk	0.678	0.322
H74.0 Tympanosclerosis	0.677	0.323
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.677	0.323
S26 Injury of heart	0.677	0.323
S25 Injury of blood vessels of thorax	0.677	0.323
S24 Injury of nerves and spinal cord at thorax level	0.677	0.323
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.677	0.323
Z34 Supervision of normal pregnancy	0.676	0.324
Chapter XXII Codes for special purposes	0.676	0.324
H61.0 Perichondritis of external ear	0.675	0.325
D53 Other nutritional anaemias	0.675	0.325
E23.0 Hypopituitarism	0.675	0.325
S99 Other and unspecified injuries of ankle and foot	0.675	0.325
C24.1 Ampulla of Vater	0.675	0.325
C92.0 Acute myeloid leukaemia	0.675	0.325
D04.4 Skin of scalp and neck	0.673	0.326
C26 Malignant neoplasm of other and ill-defined digestive organs	0.673	0.327
E05 Thyrotoxicosis [hyperthyroidism]	0.672	0.328
S29 Other and unspecified injuries of thorax	0.672	0.328
C90.2 Plasmacytoma, extramedullary	0.671	0.329
E85 Amyloidosis	0.670	0.330
E84 Cystic fibrosis	0.670	0.330
E79 Disorders of purine and pyrimidine metabolism	0.670	0.330
E77 Disorders of glycoprotein metabolism	0.670	0.330
E76 Disorders of glycosaminoglycan metabolism	0.670	0.330
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.670	0.330
E74 Other disorders of carbohydrate metabolism	0.670	0.330
E73 Lactose intolerance	0.670	0.330
E72 Other disorders of amino-acid metabolism	0.670	0.330
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.670	0.330
E70 Disorders of aromatic amino-acid metabolism	0.670	0.330
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.670	0.330
D47.3 Essential (haemorrhagic) thrombocythaemia	0.670	0.330
M46 Other inflammatory spondylopathies	0.669	0.331
D48.1 Connective and other soft tissue	0.669	0.331
Q38-Q45 Other congenital malformations of the digestive system	0.669	0.331
M86-M90 Other osteopathies	0.668	0.332
T87 Complications peculiar to reattachment and amputation	0.668	0.332
M72.9 Fibroblastic disorder, unspecified	0.667	0.333
M72.8 Other fibroblastic disorders	0.667	0.333
M72.6 Necrotizing fasciitis	0.667	0.333
M72.5 Fasciitis, not elsewhere classified	0.667	0.333
M72.4 Pseudosarcomatous fibromatosis	0.667	0.333
M72.3 Nodular fasciitis	0.667	0.333
M72.1 Knuckle pads	0.667	0.333
C54.1 Endometrium	0.667	0.333
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.667	0.333
D07 Carcinoma in situ of other and unspecified genital organs	0.666	0.334
M50-M54 Other dorsopathies	0.666	0.334
D02 Carcinoma in situ of middle ear and respiratory system	0.665	0.335
D01 Carcinoma in situ of other and unspecified digestive organs	0.665	0.335
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.665	0.335
C91 Lymphoid leukaemia	0.665	0.335
S22.0 Fracture of thoracic vertebra	0.664	0.336
S30 Superficial injury of abdomen, lower back and pelvis	0.664	0.336
T93.9 Sequelae of unspecified injury of lower limb	0.663	0.337
L57 Skin changes due to chronic exposure to nonionising radiation	0.663	0.337
S22.3 Fracture of rib	0.661	0.339
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.661	0.339
Z39 Postpartum care and examination	0.660	0.340
S12 Fracture of neck	0.660	0.340
S06 Intracranial injury	0.660	0.340
D68.6 Other Thrombophilia	0.660	0.340
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.660	0.340
C82.6 Cutaneous follicle centre lymphoma	0.660	0.340
C82.5 Diffuse follicle centre lymphoma	0.660	0.340
C82.4 Follicular lymphoma grade IIIb	0.660	0.340
C82.3 Follicular lymphoma grade IIIa	0.660	0.340
C82.2 Large cell, follicular	0.660	0.340
C82.1 Mixed small cleaved and large cell, follicular	0.660	0.340
C82.0 Small cleaved cell, follicular	0.660	0.340
E61 Deficiency of other nutrient elements	0.659	0.341
S01.5 Open wound of lip and oral cavity	0.659	0.341
T90.8 Sequelae of other specified injuries of head	0.658	0.342
T90.4 Sequelae of injury of eye and orbit	0.658	0.342
T90.3 Sequelae of injury of cranial nerves	0.658	0.342
T90.1 Sequelae of open wound of head	0.658	0.342
T90.0 Sequelae of superficial injury of head	0.658	0.342
M93 Other osteochondropathies	0.657	0.343
E55.9 Vitamin D deficiency, unspecified	0.657	0.343
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.657	0.343
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.657	0.343
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.657	0.343
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.657	0.343
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.657	0.343
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.657	0.343
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.657	0.343
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.657	0.343
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.657	0.343
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.657	0.343
D52 Folate deficiency anaemia	0.657	0.343
E11.4 With neurological complications	0.656	0.344
C18.1 Appendix	0.656	0.344
T92.0 Sequelae of open wound of upper limb	0.656	0.344
D46.9 Myelodysplastic syndrome, unspecified	0.656	0.344
S22.5 Flail chest	0.654	0.346
T80 Complications following infusion, transfusion and therapeutic injection	0.653	0.347
S98 Traumatic amputation of ankle and foot	0.653	0.347
S97 Crushing injury of ankle and foot	0.653	0.347
S96 Injury of muscle and tendon at ankle and foot level	0.653	0.347
S95 Injury of blood vessels at ankle and foot level	0.653	0.347
S94 Injury of nerves at ankle and foot level	0.653	0.347
C18.8 Overlapping lesion of colon	0.653	0.347
H60 Otitis externa	0.653	0.347
Chapter XX External causes of morbidity and mortality	0.653	0.347
M05-M14 Inflammatory polyarthropathies	0.653	0.347
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.653	0.347
H69.9 Eustachian tube disorder, unspecified	0.653	0.347
M48.0 Spinal stenosis	0.652	0.348
E78.4 Other hyperlipidaemia	0.652	0.348
H62 Disorders of external ear in diseases classified elsewhere	0.651	0.349
T93.8 Sequelae of other specified injuries of lower limb	0.650	0.350
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.650	0.350
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.650	0.350
T93.4 Sequelae of injury of nerve of lower limb	0.650	0.350
T93.1 Sequelae of fracture of femur	0.650	0.350
T93.0 Sequelae of open wound of lower limb	0.650	0.350
Q60-Q64 Congenital malformations of the urinary system	0.650	0.350
D75 Other diseases of blood and blood-forming organs	0.649	0.351
T79.7 Traumatic subcutaneous emphysema	0.648	0.352
C51 Malignant neoplasm of vulva	0.648	0.352
H61.3 Acquired stenosis of external ear canal	0.646	0.354
C24.0 Extrahepatic bile duct	0.645	0.355
F20 Schizophrenia	0.645	0.355
T91.3 Sequelae of injury of spinal cord	0.644	0.356
M94 Other disorders of cartilage	0.644	0.356
H74.9 Disorder of middle ear and mastoid, unspecified	0.643	0.357
H74.2 Discontinuity and dislocation of ear ossicles	0.643	0.357
H74.1 Adhesive middle ear disease	0.643	0.357
C15 Malignant neoplasm of oesophagus	0.642	0.358
S91.0 Open wound of ankle	0.641	0.359
E89.2 Postprocedural hypoparathyroidism	0.641	0.359
Z35 Supervision of high-risk pregnancy	0.641	0.359
S02 Fracture of skull and facial bones	0.641	0.359
Z29 Need for other prophylactic measures	0.641	0.359
M45 Ankylosing spondylitis	0.639	0.361
C81 Hodgkin's disease	0.638	0.362
D86.0 Sarcoidosis of lung	0.638	0.362
C16.0 Cardia	0.638	0.362
E04.0 Non-toxic diffuse goitre	0.637	0.363
E34 Other endocrine disorders	0.637	0.363
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.637	0.363
S22.2 Fracture of sternum	0.636	0.363
H61.1 Non-infective disorders of pinna	0.636	0.364
E35 Disorders of endocrine glands in diseases classified elsewhere	0.636	0.364
E32 Diseases of thymus	0.636	0.364
E31 Polyglandular dysfunction	0.636	0.364
E30 Disorders of puberty, not elsewhere classified	0.636	0.364
E26 Hyperaldosteronism	0.636	0.364
E25 Adrenogenital disorders	0.636	0.364
E20 Hypoparathyroidism	0.636	0.364
Q80-Q89 Other congenital malformations	0.636	0.364
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.635	0.365
M71 Other bursopathies	0.635	0.365
H74.8 Other specified disorders of middle ear and mastoid	0.634	0.366
Chapter XV Pregnancy, childbirth and the puerperium	0.634	0.366
M48.09 Spinal stenosis (Site unspecified)	0.633	0.367
S32 Fracture of lumbar spine and pelvis	0.632	0.368
C18.4 Transverse colon	0.632	0.368
S10 Superficial injury of neck	0.632	0.368
D04.6 Skin of upper limb, including shoulder	0.631	0.369
Z31 Procreative management	0.631	0.369
C32.9 Larynx, unspecified	0.630	0.370
E64 Sequelae of malnutrition and other nutritional deficiencies	0.630	0.370
E63 Other nutritional deficiencies	0.630	0.370
E56 Other vitamin deficiencies	0.630	0.370
E51 Thiamine deficiency	0.630	0.370
E50 Vitamin A deficiency	0.630	0.370
E60 Dietary zinc deficiency	0.630	0.370
E59 Dietary selenium deficiency	0.630	0.370
E58 Dietary calcium deficiency	0.630	0.370
E54 Ascorbic acid deficiency	0.630	0.370
E52 Niacin deficiency [pellagra]	0.630	0.370
T91.1 Sequelae of fracture of spine	0.630	0.370
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.629	0.371
C18.3 Hepatic flexure	0.629	0.371
C25.0 Head of pancreas	0.627	0.373
T92.9 Sequelae of unspecified injury of upper limb	0.626	0.374
T92.8 Sequelae of other specified injuries of upper limb	0.626	0.374
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.626	0.374
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.626	0.374
T92.4 Sequelae of injury of nerve of upper limb	0.626	0.374
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.626	0.374
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.625	0.375
E14 Unspecified diabetes mellitus	0.625	0.375
H70.9 Mastoiditis, unspecified	0.625	0.375
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.625	0.375
T91.4 Sequelae of injury of intrathoracic organs	0.625	0.375
T91.2 Sequelae of other fracture of thorax and pelvis	0.625	0.375
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.625	0.375
E29 Testicular dysfunction	0.625	0.375
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.624	0.375
E87.4 Mixed disorder of acid-base balance	0.624	0.376
D50.1 Sideropenic dysphagia	0.624	0.376
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.624	0.376
E27 Other disorders of adrenal gland	0.623	0.377
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.623	0.377
Z71.2 Person consulting for explanation of investigation findings	0.622	0.378
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.622	0.378
C75 Malignant neoplasm of other endocrine glands and related structures	0.621	0.379
C74 Malignant neoplasm of adrenal gland	0.621	0.379
D68.2 Hereditary deficiency of other clotting factors	0.621	0.379
D06 Carcinoma in situ of cervix uteri	0.620	0.380
S08 Traumatic amputation of part of head	0.620	0.380
S07 Crushing injury of head	0.620	0.380
S04 Injury of cranial nerves	0.620	0.380
S03 Dislocation, sprain and strain of joints and ligaments of head	0.620	0.380
F33 Recurrent depressive disorder	0.620	0.380
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.620	0.380
D86.9 Sarcoidosis, unspecified	0.619	0.380
D03.2 Melanoma in situ of ear and external auricular canal	0.619	0.381
H73.9 Disorder of tympanic membrane, unspecified	0.619	0.381
H73.1 Chronic myringitis	0.619	0.381
H73.0 Acute myringitis	0.619	0.381
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.619	0.381
C70 Malignant neoplasm of meninges	0.619	0.381
F80-F89 Disorders of psychological development	0.618	0.382
M75.8 Other shoulder lesions	0.618	0.382
E28 Ovarian dysfunction	0.618	0.382
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.616	0.384
E87.5 Hyperkalaemia	0.615	0.385
D84 Other immunodeficiencies	0.615	0.385
D83 Common variable immunodeficiency	0.615	0.385
D82 Immunodeficiency associated with other major defects	0.615	0.385
D81 Combined immunodeficiencies	0.615	0.385
D80 Immunodeficiency with predominantly antibody defects	0.615	0.385
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.615	0.385
Q35-Q37 Cleft lip and cleft palate	0.615	0.385
Q30-Q34 Congenital malformations of the respiratory system	0.615	0.385
M20-M25 Other joint disorders	0.614	0.386
H61.9 Disorder of external ear, unspecified	0.613	0.387
E06 Thyroiditis	0.612	0.388
M00 Pyogenic arthritis	0.611	0.389
M65 Synovitis and tenosynovitis	0.611	0.389
C18.6 Descending colon	0.610	0.389
T88.4 Failed or difficult intubation	0.610	0.390
S22.9 Fracture of bony thorax, part unspecified	0.610	0.390
S22.8 Fracture of other parts of bony thorax	0.610	0.390
S22.1 Multiple fractures of thoracic spine	0.610	0.390
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.610	0.390
E89.8 Other postprocedural endocrine and metabolic disorders	0.610	0.390
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.610	0.390
E89.5 Postprocedural testicular hypofunction	0.610	0.390
E89.4 Postprocedural ovarian failure	0.610	0.390
E89.1 Postprocedural hypoinsulinaemia	0.610	0.390
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.610	0.390
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.609	0.390
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.609	0.390
T82.4 Mechanical complication of vascular dialysis catheter	0.609	0.390
T82.0 Mechanical complication of heart valve prosthesis	0.609	0.390
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.609	0.391
E00 Congenital iodine-deficiency syndrome	0.609	0.391
E02 Subclinical iodine-deficiency hypothyroidism	0.609	0.391
E78.8 Other disorders of lipoprotein metabolism	0.607	0.392

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations