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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3763313
log Bayes Factor = 129.358
Chromosome 6   position 32,376,471  (GRCh37) Explore rs3763313 on Ensembl!
Variant rs3763313 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
K50 Crohn's disease [regional enteritis]
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
K50.1 Crohn's disease of large intestine
1.000 0.000 0.000
K50-K52 Noninfective enteritis and colitis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.997 0.003 0.000
C44.7 Skin of lower limb, including hip
0.995 0.005 0.000
E10.3 With ophthalmic complications
0.000 0.005 0.995
K50.9 Crohn's disease, unspecified
0.994 0.006 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.993 0.007 0.000
E10.1 With ketoacidosis
0.000 0.008 0.992
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.992 0.008 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.991 0.009 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.011 0.989
C44.5 Skin of trunk
0.987 0.013 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.014 0.986
D86 Sarcoidosis
0.000 0.016 0.984
E05.9 Thyrotoxicosis, unspecified
0.000 0.016 0.984
E16 Other disorders of pancreatic internal secretion
0.000 0.019 0.981
K51.4 Pseudopolyposis of colon
0.980 0.020 0.000
C44.4 Skin of scalp and neck
0.977 0.023 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.031 0.969
C44.2 Skin of ear and external auricular canal
0.967 0.033 0.000
C82.0 Small cleaved cell, follicular
0.967 0.033 0.000
Chapter II Neoplasms
0.967 0.033 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.964 0.036 0.000
C73 Malignant neoplasm of thyroid gland
0.958 0.042 0.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.044 0.955
D86.0 Sarcoidosis of lung
0.000 0.045 0.955
E20-E35 Disorders of other endocrine glands
0.000 0.048 0.952
D50-D53 Nutritional anaemias
0.000 0.051 0.949
T42.4 Benzodiazepines
0.947 0.053 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.053 0.946
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.946 0.054 0.000
E27 Other disorders of adrenal gland
0.000 0.055 0.945
E27.1 Primary adrenocortical insufficiency
0.000 0.057 0.943
K90 Intestinal malabsorption
0.000 0.057 0.943
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.939 0.061 0.000
K51.2 Ulcerative (chronic) proctitis
0.937 0.063 0.000
D51 Vitamin B12 deficiency anaemia
0.000 0.063 0.937
C83 Diffuse non-Hodgkin's lymphoma
0.936 0.064 0.000
D50 Iron deficiency anaemia
0.000 0.068 0.932
D50.9 Iron deficiency anaemia, unspecified
0.000 0.069 0.931
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.922 0.078 0.000
C44.1 Skin of eyelid, including canthus
0.922 0.078 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.920 0.080 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.080 0.920
C83.3 Large cell (diffuse)
0.917 0.083 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.917 0.083 0.000
C43 Malignant melanoma of skin
0.916 0.084 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.905 0.095 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.111 0.889
C02 Malignant neoplasm of other and unspecified parts of tongue
0.888 0.112 0.000
E10.4 With neurological complications
0.000 0.112 0.888
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.886 0.114 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.122 0.878
C82.2 Large cell, follicular
0.873 0.127 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.870 0.130 0.000
D69 Purpura and other haemorrhagic conditions
0.000 0.135 0.865
K51.8 Other ulcerative colitis
0.865 0.135 0.000
T43.2 Other and unspecified antidepressants
0.858 0.142 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.856 0.144 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.144 0.855
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.148 0.852
C74 Malignant neoplasm of adrenal gland
0.852 0.148 0.000
C82.3 Follicular lymphoma grade IIIa
0.851 0.149 0.000
K50.8 Other Crohn's disease
0.850 0.150 0.000
D69.6 Thrombocytopenia, unspecified
0.000 0.150 0.850
T50.9 Other and unspecified drugs, medicaments and biological substances
0.839 0.161 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.833 0.167 0.000
E10.0 With coma
0.000 0.175 0.825
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.821 0.179 0.000
D86.1 Sarcoidosis of lymph nodes
0.000 0.179 0.821
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.181 0.819
E03.8 Other specified hypothyroidism
0.000 0.187 0.813
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.192 0.808
E10.2 With renal complications
0.000 0.198 0.802
L40.4 Guttate psoriasis
0.800 0.200 0.000
C09 Malignant neoplasm of tonsil
0.800 0.200 0.000
D86.8 Sarcoidosis of other and combined sites
0.000 0.205 0.795
M07.39 Other psoriatic arthropathies (Site unspecified)
0.794 0.206 0.000
L40-L45 Papulosquamous disorders
0.793 0.207 0.000
M07.3 Other psoriatic arthropathies
0.792 0.208 0.000
E10.8 With unspecified complications
0.000 0.220 0.780
C06 Malignant neoplasm of other and unspecified parts of mouth
0.780 0.220 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.775 0.225 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.773 0.227 0.000
C02.9 Tongue, unspecified
0.769 0.231 0.000
C82.4 Follicular lymphoma grade IIIb
0.762 0.237 0.000
L40.1 Generalised pustular psoriasis
0.762 0.237 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.761 0.239 0.000
D52 Folate deficiency anaemia
0.000 0.240 0.760
K50.0 Crohn's disease of small intestine
0.753 0.247 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.753 0.247 0.000
E20 Hypoparathyroidism
0.000 0.249 0.751
E24 Cushing's syndrome
0.000 0.249 0.751
C44.0 Skin of lip
0.749 0.251 0.000
E10.6 With other specified complications
0.000 0.251 0.749
C02.2 Ventral surface of tongue
0.747 0.253 0.000
K90.8 Other intestinal malabsorption
0.000 0.256 0.744
E14 Unspecified diabetes mellitus
0.000 0.258 0.741
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.741 0.259 0.000
K51.5 Mucosal proctocolitis
0.738 0.262 0.000
Z93.2 Ileostomy status
0.737 0.263 0.000
C02.1 Border of tongue
0.736 0.264 0.000
C44.6 Skin of upper limb, including shoulder
0.733 0.267 0.000
C95 Leukaemia of unspecified cell type
0.733 0.267 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.733 0.267 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.731 0.269 0.000
E27.2 Addisonian crisis
0.000 0.269 0.731
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.273 0.727
L40.3 Pustulosis palmaris et plantaris
0.726 0.274 0.000
D69.9 Haemorrhagic condition, unspecified
0.000 0.274 0.726
C74.9 Adrenal gland, unspecified
0.726 0.274 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.720 0.280 0.000
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
C82.6 Cutaneous follicle centre lymphoma
0.717 0.283 0.000
C82.5 Diffuse follicle centre lymphoma
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.715 0.285 0.000
C94 Other leukaemias of specified cell type
0.715 0.285 0.000
C93 Monocytic leukaemia
0.715 0.285 0.000
C86 Other specified types of T/NK-cell lymphoma
0.715 0.285 0.000
C85.1 B-cell lymphoma, unspecified
0.713 0.287 0.000
E10.5 With peripheral circulatory complications
0.000 0.287 0.713
J45 Asthma
0.000 0.287 0.713
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.712 0.288 0.000
C85.0 Lymphosarcoma
0.712 0.288 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.711 0.289 0.000
E07 Other disorders of thyroid
0.000 0.289 0.711
E29 Testicular dysfunction
0.000 0.290 0.710
C13 Malignant neoplasm of hypopharynx
0.710 0.290 0.000
T38.1 Thyroid hormones and substitutes
0.709 0.291 0.000
E16.1 Other hypoglycaemia
0.000 0.291 0.709
E15 Nondiabetic hypoglycaemic coma
0.000 0.291 0.709
D69.4 Other primary thrombocytopenia
0.000 0.293 0.707
C10 Malignant neoplasm of oropharynx
0.706 0.293 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.294 0.705
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.296 0.703
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.296 0.703
E16.4 Abnormal secretion of gastrin
0.000 0.296 0.703
E16.3 Increased secretion of glucagon
0.000 0.296 0.703
D80 Immunodeficiency with predominantly antibody defects
0.000 0.297 0.703
T42.0 Hydantoin derivatives
0.703 0.297 0.000
L43 Lichen planus
0.702 0.298 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.701 0.299 0.000
C09.9 Tonsil, unspecified
0.701 0.299 0.000
E05.8 Other thyrotoxicosis
0.000 0.300 0.700
C74.0 Cortex of adrenal gland
0.698 0.302 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.697 0.303 0.000
C01 Malignant neoplasm of base of tongue
0.695 0.305 0.000
C11 Malignant neoplasm of nasopharynx
0.695 0.305 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.689 0.311 0.000
D82 Immunodeficiency associated with other major defects
0.000 0.315 0.685
D81 Combined immunodeficiencies
0.000 0.315 0.685
C03 Malignant neoplasm of gum
0.684 0.316 0.000
L40.8 Other psoriasis
0.683 0.317 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.318 0.682
E32 Diseases of thymus
0.000 0.318 0.682
E31 Polyglandular dysfunction
0.000 0.318 0.682
E30 Disorders of puberty, not elsewhere classified
0.000 0.318 0.682
C12 Malignant neoplasm of pyriform sinus
0.682 0.318 0.000
E34 Other endocrine disorders
0.000 0.318 0.682
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.320 0.680
E22 Hyperfunction of pituitary gland
0.000 0.320 0.680
C83.1 Small cleaved cell (diffuse)
0.679 0.321 0.000
L40.0 Psoriasis vulgaris
0.679 0.321 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.678 0.322 0.000
T42.3 Barbiturates
0.678 0.322 0.000
T42.2 Succinimides and oxazolidinediones
0.678 0.322 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.678 0.322 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.322 0.677
E27.0 Other adrenocortical overactivity
0.000 0.322 0.677
K90.3 Pancreatic steatorrhoea
0.000 0.324 0.676
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.324 0.676
K90.1 Tropical sprue
0.000 0.324 0.676
E40-E46 Malnutrition
0.000 0.327 0.673
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.328 0.672
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.328 0.672
D51.2 Transcobalamin II deficiency
0.000 0.328 0.672
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.328 0.672
C83.7 Burkitt's tumour
0.671 0.329 0.000
C83.6 Undifferentiated (diffuse)
0.671 0.329 0.000
C83.5 Lymphoblastic (diffuse)
0.671 0.329 0.000
C83.4 Immunoblastic (diffuse)
0.671 0.329 0.000
C83.2 Mixed small and large cell (diffuse)
0.671 0.329 0.000
T50.4 Drugs affecting uric acid metabolism
0.670 0.330 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.669 0.331 0.000
D53 Other nutritional anaemias
0.000 0.331 0.669
C05 Malignant neoplasm of palate
0.669 0.331 0.000
D50.1 Sideropenic dysphagia
0.000 0.331 0.668
C02.4 Lingual tonsil
0.666 0.334 0.000
E06 Thyroiditis
0.000 0.336 0.664
C04 Malignant neoplasm of floor of mouth
0.662 0.338 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.657 0.343 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.657 0.343 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.657 0.343 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.657 0.343 0.000
C43.8 Overlapping malignant melanoma of skin
0.657 0.343 0.000
C43.0 Malignant melanoma of lip
0.657 0.343 0.000
D69.0 Allergic purpura
0.000 0.344 0.656
L42 Pityriasis rosea
0.655 0.345 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.345 0.655
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.651 0.349 0.000
D83 Common variable immunodeficiency
0.000 0.349 0.651
J45.0 Predominantly allergic asthma
0.000 0.351 0.649
L43.9 Lichen planus, unspecified
0.649 0.351 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.649 0.351 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.353 0.647
C00 Malignant neoplasm of lip
0.647 0.353 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.644 0.356 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.643 0.357 0.000
C06.0 Cheek mucosa
0.640 0.360 0.000
C02.8 Overlapping lesion of tongue
0.637 0.363 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.637 0.363 0.000
C02.0 Dorsal surface of tongue
0.637 0.363 0.000
T50.7 Analeptics and opioid receptor antagonists
0.635 0.365 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.635 0.365 0.000
T50.5 Appetite depressants
0.635 0.365 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.635 0.365 0.000
T50.1 Loop [high-ceiling] diuretics
0.635 0.365 0.000
T50.0 Mineralocorticoids and their antagonists
0.635 0.365 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.635 0.365 0.000
C43.4 Malignant melanoma of scalp and neck
0.632 0.368 0.000
D67 Hereditary factor IX deficiency
0.000 0.370 0.629
D69.5 Secondary thrombocytopenia
0.000 0.374 0.626
D52.9 Folate deficiency anaemia, unspecified
0.000 0.375 0.625
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.625 0.375 0.000
E14.3 With ophthalmic complications
0.000 0.376 0.624
T43.9 Psychotropic drug, unspecified
0.624 0.376 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.624 0.376 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.624 0.376 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.623 0.376 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.622 0.378 0.000
D69.8 Other specified haemorrhagic conditions
0.000 0.380 0.620
T50.8 Diagnostic agents
0.620 0.380 0.000
T36 Poisoning by systemic antibiotics
0.618 0.382 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.387 0.613
T42.1 Iminostilbenes
0.611 0.389 0.000
C74.1 Medulla of adrenal gland
0.611 0.389 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.391 0.609
E20.9 Hypoparathyroidism, unspecified
0.000 0.392 0.608
D86.3 Sarcoidosis of skin
0.000 0.395 0.605
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.605 0.395 0.000
M07 Psoriatic and enteropathic arthropathies
0.602 0.398 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.398 0.602
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.404 0.596
E24.9 Cushing's syndrome, unspecified
0.000 0.407 0.593
C44.9 Malignant neoplasm of skin, unspecified
0.593 0.407 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.589 0.411 0.000
T38.9 Other and unspecified hormone antagonists
0.589 0.411 0.000
T38.7 Androgens and anabolic congeners
0.589 0.411 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.589 0.411 0.000
T38.5 Other oestrogens and progestogens
0.589 0.411 0.000
T38.4 Oral contraceptives
0.589 0.411 0.000
T38.2 Antithyroid drugs
0.589 0.411 0.000
T38.0 Glucocorticoids and synthetic analogues
0.589 0.411 0.000
C06.2 Retromolar area
0.587 0.413 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.585 0.415 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.415 0.585
C43.2 Malignant melanoma of ear and external auricular canal
0.585 0.415 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.583 0.416 0.000
E25 Adrenogenital disorders
0.000 0.417 0.583
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.580 0.420 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.424 0.576
T43.6 Psychostimulants with abuse potential
0.576 0.424 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.575 0.425 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.574 0.426 0.000
C09.8 Overlapping lesion of tonsil
0.574 0.426 0.000
C09.1 Tonsillar pillar (anterior) (posterior)
0.574 0.426 0.000
C09.0 Tonsillar fossa
0.574 0.426 0.000
C06.9 Mouth, unspecified
0.573 0.427 0.000
E13 Other specified diabetes mellitus
0.000 0.430 0.570
L44 Other papulosquamous disorders
0.568 0.431 0.000
L41 Parapsoriasis
0.568 0.431 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.568 0.431 0.000
M07.38 Other psoriatic arthropathies (Other)
0.568 0.432 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.568 0.432 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.568 0.432 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.568 0.432 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.568 0.432 0.000
C95.0 Acute leukaemia of unspecified cell type
0.568 0.432 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.567 0.432 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.434 0.566
E34.0 Carcinoid syndrome
0.000 0.440 0.560
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.559 0.441 0.000
C06.1 Vestibule of mouth
0.559 0.441 0.000
D66 Hereditary factor VIII deficiency
0.000 0.441 0.558
E14.9 Without complications
0.000 0.442 0.558
E06.9 Thyroiditis, unspecified
0.000 0.443 0.557
D84 Other immunodeficiencies
0.001 0.443 0.556
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.446 0.553
C88 Malignant immunoproliferative diseases
0.553 0.447 0.000
D69.2 Other nonthrombocytopenic purpura
0.000 0.452 0.547
C13.9 Hypopharynx, unspecified
0.546 0.453 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.545 0.455 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.545 0.455 0.000
T47.7 Emetics
0.545 0.455 0.000
T47.6 Antidiarrhoeal drugs
0.545 0.455 0.000
T47.5 Digestants
0.545 0.455 0.000
T47.4 Other laxatives
0.545 0.455 0.000
T47.3 Saline and osmotic laxatives
0.545 0.455 0.000
T47.2 Stimulant laxatives
0.545 0.455 0.000
T47.0 Histamine H(2)-receptor antagonists
0.545 0.455 0.000
D52.8 Other folate deficiency anaemias
0.000 0.455 0.545
D52.1 Drug-induced folate deficiency anaemia
0.000 0.455 0.545
D52.0 Dietary folate deficiency anaemia
0.000 0.455 0.545
E27.9 Disorder of adrenal gland, unspecified
0.000 0.456 0.544
C10.9 Oropharynx, unspecified
0.540 0.460 0.000
E20.8 Other hypoparathyroidism
0.000 0.461 0.539
E20.1 Pseudohypoparathyroidism
0.000 0.461 0.539
E20.0 Idiopathic hypoparathyroidism
0.000 0.461 0.539
E24.8 Other Cushing's syndrome
0.000 0.461 0.538
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.461 0.538
E24.3 Ectopic ACTH syndrome
0.000 0.461 0.538
E24.1 Nelson's syndrome
0.000 0.461 0.538
E29.1 Testicular hypofunction
0.000 0.463 0.537
E14.8 With unspecified complications
0.000 0.468 0.532
E14.7 With multiple complications
0.000 0.468 0.532
E14.2 Withrenal complications
0.000 0.468 0.532
E14.1 With ketoacidosis
0.000 0.468 0.532
E14.0 With coma
0.000 0.468 0.532
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.531 0.469 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.531 0.469 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.531 0.469 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.531 0.469 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.531 0.469 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.531 0.469 0.000
T44.0 Anticholinesterase agents
0.531 0.469 0.000
D69.1 Qualitative platelet defects
0.000 0.469 0.531
C85.7 Other specified types of non-Hodgkin's lymphoma
0.529 0.471 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.471 0.529
C84.0 Mycosis fungoides
0.528 0.472 0.000
C05.0 Hard palate
0.527 0.472 0.000
E14.6 With other specified complications
0.000 0.473 0.527
C95.7 Other leukaemia of unspecified cell type
0.526 0.474 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.526 0.474 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.526 0.474 0.000
C08.0 Submandibular gland
0.523 0.476 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.521 0.479 0.000
C11.9 Nasopharynx, unspecified
0.520 0.480 0.000
D55-D59 Haemolytic anaemias
0.001 0.481 0.518
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.481 0.519
C84.9 Mature T/NK-cell lymphoma, unspecified
0.516 0.483 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.516 0.483 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.516 0.483 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.516 0.483 0.000
C84.3 Lymphoepithelioid lymphoma
0.516 0.483 0.000
C84.2 T-zone lymphoma
0.516 0.483 0.000
C84.1 Sezary's diease
0.516 0.483 0.000
C84.5 Other and unspecified T-cell lymphomas
0.514 0.485 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
C75.9 Endocrine gland, unspecified
0.513 0.486 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.487 0.513
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.513 0.487 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.513 0.487 0.000
C86.4 Blastic NK-cell lymphoma
0.513 0.487 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.513 0.487 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.513 0.487 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.513 0.487 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.513 0.487 0.000
C93.9 Monocytic leukaemia, unspecified
0.513 0.487 0.000
C93.7 Other monocytic leukaemia
0.513 0.487 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.513 0.487 0.000
C93.2 Subacute monocytic leukaemia
0.513 0.487 0.000
C93.1 Chronic monocytic leukaemia
0.513 0.487 0.000
C93.0 Acute monocytic leukaemia
0.513 0.487 0.000
C94.7 Other specified leukaemias
0.513 0.487 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.513 0.487 0.000
C94.5 Acute myelofibrosis
0.513 0.487 0.000
C94.4 Acute panmyelosis
0.513 0.487 0.000
C94.3 Mast cell leukaemia
0.513 0.487 0.000
C94.2 Acute megakaryoblastic leukaemia
0.513 0.487 0.000
C94.1 Chronic erythraemia
0.513 0.487 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.513 0.487 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.513 0.487 0.000
C96.8 Histiocytic sarcoma
0.513 0.487 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.513 0.487 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.513 0.487 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.513 0.487 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.513 0.487 0.000
C96.3 True histiocytic lymphoma
0.513 0.487 0.000
C96.2 Malignant mast cell tumour
0.513 0.487 0.000
C96.1 Malignant histiocytosis
0.513 0.487 0.000
C96.0 Letterer-Siwe disease
0.513 0.487 0.000
E07.8 Other specified disorders of thyroid
0.000 0.488 0.512
E26 Hyperaldosteronism
0.000 0.488 0.512
C84.4 Peripheral T-cell lymphoma
0.512 0.488 0.000
J45.8 Mixed asthma
0.000 0.489 0.511
J45.1 Nonallergic asthma
0.000 0.489 0.511
E07.1 Dyshormogenetic goitre
0.000 0.490 0.510
E07.0 Hypersecretion of calcitonin
0.000 0.490 0.510
E29.9 Testicular dysfunction, unspecified
0.000 0.491 0.509
E29.8 Other testicular dysfunction
0.000 0.491 0.509
E29.0 Testicular hyperfunction
0.000 0.491 0.509
C13.8 Overlapping lesion of hypopharynx
0.509 0.491 0.000
C13.2 Posterior wall of hypopharynx
0.509 0.491 0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect
0.509 0.491 0.000
C13.0 Postcricoid region
0.509 0.491 0.000
T45.0 Antiallergic and antiemetic drugs
0.507 0.493 0.000
C10.8 Overlapping lesion of oropharynx
0.506 0.493 0.000
C10.4 Branchial cleft
0.506 0.493 0.000
C10.3 Posterior wall of oropharynx
0.506 0.493 0.000
C10.2 Lateral wall of oropharynx
0.506 0.493 0.000
C10.1 Anterior surface of epiglottis
0.506 0.493 0.000
C10.0 Vallecula
0.506 0.493 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.496 0.504
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.496 0.504
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.496 0.504
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.496 0.504
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.496 0.504
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.496 0.504
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.496 0.504
L43.3 Subacute (active) lichen planus
0.503 0.496 0.000
L43.2 Lichenoid drug reaction
0.503 0.496 0.000
L43.1 Bullous lichen planus
0.503 0.496 0.000
L43.0 Hypertrophic lichen planus
0.503 0.496 0.000
C75.8 Pluriglandular involvement, unspecified
0.503 0.497 0.000
C75.5 Aortic body and other paraganglia
0.503 0.497 0.000
C75.4 Carotid body
0.503 0.497 0.000
C75.3 Pineal gland
0.503 0.497 0.000
C75.2 Craniopharyngeal duct
0.503 0.497 0.000
C75.1 Pituitary gland
0.503 0.497 0.000
C75.0 Parathyroid gland
0.503 0.497 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.502 0.498 0.000
C03.1 Lower gum
0.502 0.498 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.498 0.502
E21.0 Primary hyperparathyroidism
0.000 0.498 0.502
K52 Other non-infective gastro-enteritis and colitis
0.500 0.500 0.000
C08.9 Major salivary gland, unspecified
0.500 0.500 0.000
C08.8 Overlapping lesion of major salivary glands
0.500 0.500 0.000
C08.1 Sublingual gland
0.500 0.500 0.000
C11.8 Overlapping lesion of nasopharynx
0.498 0.502 0.000
C11.3 Anterior wall of nasopharynx
0.498 0.502 0.000
C11.2 Lateral wall of nasopharynx
0.498 0.502 0.000
C11.1 Posterior wall of nasopharynx
0.498 0.502 0.000
C11.0 Superior wall of nasopharynx
0.498 0.502 0.000
C95.9 Leukaemia, unspecified
0.495 0.504 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.494 0.506 0.000
D81.9 Combined immunodeficiency, unspecified
0.000 0.509 0.491
D81.8 Other combined immunodeficiencies
0.000 0.509 0.491
D81.7 Major histocompatibility complex class II deficiency
0.000 0.509 0.491
D81.6 Major histocompatibility complex class I deficiency
0.000 0.509 0.491
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.509 0.491
D81.4 Nezelof's syndrome
0.000 0.509 0.491
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.509 0.491
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.509 0.491
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.509 0.491
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.509 0.491
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.509 0.491
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.509 0.491
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.509 0.491
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.509 0.491

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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