TreeWAS – Variant ID: rs3768939

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I42.0 Dilated cardiomyopathy	0.000	0.955	0.045
C34.9 Bronchus or lung, unspecified	0.035	0.965	0.000
O16 Unspecified maternal hypertension	0.034	0.966	0.000
I42 Cardiomyopathy	0.000	0.975	0.025
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.023	0.977	0.000
O80.0 Spontaneous vertex delivery	0.021	0.979	0.000
I42.8 Other cardiomyopathies	0.000	0.980	0.020
O82.1 Delivery by emergency Caesarean section	0.020	0.980	0.000
O80-O84 Delivery	0.020	0.980	0.000
O82 Single delivery by Caesarean section	0.020	0.980	0.000
I42.2 Other hypertrophic cardiomyopathy	0.000	0.981	0.019
O80 Single spontaneous delivery	0.019	0.981	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.019	0.981	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.982	0.018
I42.5 Other restrictive cardiomyopathy	0.000	0.982	0.018
I42.4 Endocardial fibroelastosis	0.000	0.982	0.018
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.982	0.018
I42.6 Alcoholic cardiomyopathy	0.000	0.982	0.018
T40.2 Other opioids	0.018	0.982	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.017	0.983	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.017	0.983	0.000
N35.9 Urethral stricture, unspecified	0.000	0.983	0.017
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.983	0.017
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.017	0.983	0.000
O15 Eclampsia	0.016	0.983	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.017	0.983	0.000
O20 Haemorrhage in early pregnancy	0.016	0.984	0.000
O20.0 Threatened abortion	0.016	0.984	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.016	0.984	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.016	0.984	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.016	0.984	0.000
I44.1 Atrioventricular block, second degree	0.000	0.984	0.016
O14.0 Moderate preeclampsia	0.016	0.984	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.016	0.984	0.000
O82.0 Delivery by elective Caesarean section	0.015	0.985	0.000
O81 Single delivery by forceps and vacuum extractor	0.015	0.985	0.000
O14.1 Severe preeclampsia	0.015	0.985	0.000
O82.9 Delivery by Caesarean section, unspecified	0.015	0.985	0.000
O14.9 Preeclampsia, unspecified	0.015	0.985	0.000
O85-O92 Complications predominantly related to the puerperium	0.015	0.985	0.000
O26.9 Pregnancy-related condition, unspecified	0.015	0.985	0.000
O84 Multiple delivery	0.015	0.985	0.000
O83 Other assisted single delivery	0.015	0.985	0.000
O82.8 Other single delivery by Caesarean section	0.015	0.985	0.000
O82.2 Delivery by Caesarean hysterectomy	0.015	0.985	0.000
O12.1 Gestational proteinuria	0.014	0.985	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.014	0.986	0.000
I38 Endocarditis, valve unspecified	0.000	0.986	0.014
I30-I52 Other forms of heart disease	0.000	0.986	0.014
I44 Atrioventricular and left bundle-branch block	0.000	0.986	0.014
O80.1 Spontaneous breech delivery	0.014	0.986	0.000
O14.2 HELLP syndrome	0.014	0.986	0.000
O26.0 Excessive weight gain in pregnancy	0.014	0.986	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.014	0.986	0.000
I37 Pulmonary valve disorders	0.000	0.986	0.013
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.013	0.987	0.000
O26.8 Other specified pregnancy-related conditions	0.013	0.987	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.013	0.987	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.013	0.987	0.000
O85 Puerperal sepsis	0.013	0.987	0.000
I37.1 Pulmonary valve insufficiency	0.000	0.987	0.013
I31.3 Pericardial effusion (noninflammatory)	0.000	0.987	0.013
O80.8 Other single spontaneous delivery	0.013	0.987	0.000
C34 Malignant neoplasm of bronchus and lung	0.013	0.987	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.013	0.987	0.000
O87 Venous complications in the puerperium	0.013	0.987	0.000
O22 Venous complications in pregnancy	0.013	0.987	0.000
I31 Other diseases of pericardium	0.000	0.987	0.013
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.013	0.987	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.013	0.987	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.013	0.987	0.000
I49 Other cardiac arrhythmias	0.000	0.988	0.012
T40.5 Cocaine	0.012	0.988	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.012	0.988	0.000
I44.3 Other and unspecified atrioventricular block	0.000	0.988	0.012
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.012	0.988	0.000
I49.0 Ventricular fibrillation and flutter	0.000	0.988	0.012
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.012	0.988	0.000
I44.7 Left bundle-branch block, unspecified	0.000	0.988	0.012
O12.2 Gestational oedema with proteinuria	0.012	0.988	0.000
O81.3 Other and unspecified forceps delivery	0.012	0.988	0.000
O15.9 Eclampsia, unspecified as to time period	0.012	0.988	0.000
O15.2 Eclampsia in the puerperium	0.012	0.988	0.000
O15.1 Eclampsia in labour	0.012	0.988	0.000
O15.0 Eclampsia in pregnancy	0.012	0.988	0.000
O81.0 Low forceps delivery	0.012	0.988	0.000
O29 Complications of anaesthesia during pregnancy	0.012	0.988	0.000
O25 Malnutrition in pregnancy	0.012	0.988	0.000
T45.0 Antiallergic and antiemetic drugs	0.012	0.988	0.000
T39.0 Salicylates	0.012	0.988	0.000
O90 Complications of the puerperium, not elsewhere classified	0.012	0.988	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.012	0.988	0.000
O23 Infections of genito-urinary tract in pregnancy	0.012	0.988	0.000
O26.5 Maternal hypotension syndrome	0.012	0.988	0.000
O26.4 Herpes gestationis	0.012	0.988	0.000
O26.1 Low weight gain in pregnancy	0.012	0.988	0.000
I33 Acute and subacute endocarditis	0.000	0.988	0.012
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.012	0.988	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.012	0.988	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.012	0.988	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.012	0.988	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.011	0.988	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.011	0.988	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.011	0.988	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.011	0.988	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.011	0.988	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.011	0.988	0.000
O80.9 Single spontaneous delivery, unspecified	0.011	0.988	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.011	0.989	0.000
T40.8 Lysergide [LSD]	0.011	0.989	0.000
T40.7 Cannabis (derivatives)	0.011	0.989	0.000
T40.3 Methadone	0.011	0.989	0.000
T40.1 Heroin	0.011	0.989	0.000
T40.0 Opium	0.011	0.989	0.000
O89 Complications of anaesthesia during the puerperium	0.011	0.989	0.000
O20.8 Other haemorrhage in early pregnancy	0.011	0.989	0.000
O91 Infections of breast associated with childbirth	0.011	0.989	0.000
I44.6 Other and unspecified fascicular block	0.000	0.989	0.011
I49.5 Sick sinus syndrome	0.000	0.989	0.011
O81.5 Delivery by combination of forceps and vacuum extractor	0.011	0.989	0.000
O81.2 Mid-cavity forceps with rotation	0.011	0.989	0.000
O81.1 Mid-cavity forceps delivery	0.011	0.989	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.011	0.989	0.000
T45.2 Vitamins, not elsewhere classified	0.011	0.989	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.011	0.989	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.011	0.989	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.011	0.989	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.011	0.989	0.000
O88 Obstetric embolism	0.011	0.989	0.000
T50.8 Diagnostic agents	0.011	0.989	0.000
I47 Paroxysmal tachycardia	0.000	0.989	0.011
T36 Poisoning by systemic antibiotics	0.011	0.989	0.000
O83.9 Assisted single delivery, unspecified	0.011	0.989	0.000
O83.8 Other specified assisted single delivery	0.011	0.989	0.000
O83.4 Destructive operation for delivery	0.011	0.989	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.011	0.989	0.000
O83.2 Other manipulation-assisted delivery	0.011	0.989	0.000
O83.1 Other assisted breech delivery	0.011	0.989	0.000
O83.0 Breech extraction	0.011	0.989	0.000
O84.9 Multiple delivery, unspecified	0.011	0.989	0.000
O84.8 Other multiple delivery	0.011	0.989	0.000
O84.2 Multiple delivery, all by Caesarean section	0.011	0.989	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.011	0.989	0.000
O84.0 Multiple delivery, all spontaneous	0.011	0.989	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.011	0.989	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.011	0.989	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.010	0.989	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.010	0.989	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.010	0.989	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.010	0.989	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.010	0.989	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.010	0.989	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.010	0.989	0.000
T44.0 Anticholinesterase agents	0.010	0.989	0.000
T42.0 Hydantoin derivatives	0.011	0.989	0.000
I52 Other heart disorders in diseases classified elsewhere	0.000	0.989	0.010
I48 Atrial fibrillation and flutter	0.000	0.989	0.010
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.989	0.010
I41 Myocarditis in diseases classified elsewhere	0.000	0.989	0.010
I40 Acute myocarditis	0.000	0.989	0.010
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.989	0.010
I32 Pericarditis in diseases classified elsewhere	0.000	0.989	0.010
I44.5 Left posterior fascicular block	0.000	0.989	0.010
I49.8 Other specified cardiac arrhythmias	0.000	0.989	0.011
T45.5 Anticoagulants	0.010	0.989	0.000
I47.0 Reentry ventricular arrhythmia	0.000	0.989	0.010
C34.2 Middle lobe, bronchus or lung	0.010	0.990	0.000
O28 Abnormal findings on antenatal screening of mother	0.010	0.990	0.000
O87.8 Other venous complications in the puerperium	0.010	0.990	0.000
T42.4 Benzodiazepines	0.010	0.990	0.000
T43.6 Psychostimulants with abuse potential	0.010	0.990	0.000
O21 Excessive vomiting in pregnancy	0.010	0.990	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.010	0.990	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.010	0.990	0.000
T45.8 Other primarily systemic and haematological agents	0.010	0.990	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.010	0.990	0.000
T45.6 Fibrinolysis-affecting drugs	0.010	0.990	0.000
T45.4 Iron and its compounds	0.010	0.990	0.000
T45.3 Enzymes, not elsewhere classified	0.010	0.990	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.010	0.990	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.010	0.990	0.000
I34 Nonrheumatic mitral valve disorders	0.000	0.990	0.010
T43.0 Tricyclic and tetracyclic antidepressants	0.010	0.990	0.000
I37.9 Pulmonary valve disorder, unspecified	0.000	0.990	0.010
I37.8 Other pulmonary valve disorders	0.000	0.990	0.010
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.990	0.010
I37.0 Pulmonary valve stenosis	0.000	0.990	0.010
T43.4 Butyrophenone and thioxanthene neuroleptics	0.010	0.990	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.010	0.990	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.010	0.990	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.010	0.990	0.000
I31.0 Chronic adhesive pericarditis	0.000	0.990	0.010
T39.4 Antirheumatics, not elsewhere classified	0.010	0.990	0.000
T39.2 Pyrazolone derivatives	0.010	0.990	0.000
O90.1 Disruption of perineal obstetric wound	0.010	0.990	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.010	0.990	0.000
T43.9 Psychotropic drug, unspecified	0.010	0.990	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.010	0.990	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.010	0.990	0.000
I33.0 Acute and subacute infective endocarditis	0.000	0.990	0.010
C34.8 Overlapping lesion of bronchus and lung	0.010	0.990	0.000
I42.9 Cardiomyopathy, unspecified	0.000	0.990	0.010
O87.9 Venous complication in the puerperium, unspecified	0.009	0.990	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.009	0.990	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.009	0.990	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.009	0.990	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.009	0.990	0.000
T46.7 Peripheral vasodilators	0.009	0.990	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.009	0.990	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.009	0.990	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.009	0.990	0.000
I31.1 Chronic constrictive pericarditis	0.000	0.990	0.009
O22.9 Venous complication in pregnancy, unspecified	0.009	0.990	0.000
O22.8 Other venous complications in pregnancy	0.009	0.990	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.009	0.990	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.009	0.990	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.009	0.990	0.000
O22.1 Genital varices in pregnancy	0.009	0.990	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.009	0.990	0.000
I31.8 Other specified diseases of pericardium	0.000	0.990	0.009
I31.2 Haemopericardium, not elsewhere classified	0.000	0.990	0.009
I44.4 Left anterior fascicular block	0.000	0.990	0.009
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.009	0.991	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.009	0.991	0.000
T42.3 Barbiturates	0.009	0.991	0.000
T42.2 Succinimides and oxazolidinediones	0.009	0.991	0.000
T50.7 Analeptics and opioid receptor antagonists	0.009	0.991	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.009	0.991	0.000
T50.5 Appetite depressants	0.009	0.991	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.009	0.991	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.009	0.991	0.000
T50.1 Loop [high-ceiling] diuretics	0.009	0.991	0.000
T50.0 Mineralocorticoids and their antagonists	0.009	0.991	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.009	0.991	0.000
I49.1 Atrial premature depolarisation	0.000	0.991	0.009
T46.1 Calcium-channel blockers	0.009	0.991	0.000
I49.2 Junctional premature depolarisation	0.000	0.991	0.009
T50.4 Drugs affecting uric acid metabolism	0.009	0.991	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.009	0.991	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.009	0.991	0.000
T47.7 Emetics	0.009	0.991	0.000
T47.6 Antidiarrhoeal drugs	0.009	0.991	0.000
T47.5 Digestants	0.009	0.991	0.000
T47.4 Other laxatives	0.009	0.991	0.000
T47.3 Saline and osmotic laxatives	0.009	0.991	0.000
T47.2 Stimulant laxatives	0.009	0.991	0.000
T47.0 Histamine H(2)-receptor antagonists	0.009	0.991	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.009	0.991	0.000
N35 Urethral stricture	0.000	0.991	0.009
O26.2 Pregnancy care of habitual aborter	0.009	0.991	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.991	0.009
O87.2 Haemorrhoids in the puerperium	0.009	0.991	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.009	0.991	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.009	0.991	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.009	0.991	0.000
O29.6 Failed or difficult intubation during pregnancy	0.009	0.991	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.009	0.991	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.009	0.991	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.009	0.991	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.009	0.991	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.009	0.991	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.009	0.991	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.009	0.991	0.000
O90.5 Postpartum thyroiditis	0.009	0.991	0.000
O90.4 Postpartum acute renal failure	0.009	0.991	0.000
O90.3 Cardiomyopathy in the puerperium	0.009	0.991	0.000
O90.0 Disruption of Caesarean section wound	0.009	0.991	0.000
I30 Acute pericarditis	0.000	0.991	0.009
O81.4 Vacuum extractor delivery	0.009	0.991	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.009	0.991	0.000
O23.2 Infections of urethra in pregnancy	0.009	0.991	0.000
O23.1 Infections of bladder in pregnancy	0.009	0.991	0.000
O23.0 Infections of kidney in pregnancy	0.009	0.991	0.000
T40.4 Other synthetic narcotics	0.008	0.991	0.000
T36.3 Macrolides	0.008	0.991	0.000
O24 Diabetes mellitus in pregnancy	0.009	0.991	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.008	0.991	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.008	0.991	0.000
T37.5 Antiviral drugs	0.008	0.991	0.000
T37.4 Anthelminthics	0.008	0.991	0.000
T37.3 Other antiprotozoal drugs	0.008	0.991	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.008	0.991	0.000
T37.1 Antimycobacterial drugs	0.008	0.991	0.000
T37.0 Sulphonamides	0.008	0.991	0.000
T41.5 Therapeutic gases	0.008	0.991	0.000
T41.4 Anaesthetic, unspecified	0.008	0.991	0.000
T41.3 Local anaesthetics	0.008	0.991	0.000
T41.2 Other and unspecified general anaesthetics	0.008	0.991	0.000
T41.1 Intravenous anaesthetics	0.008	0.991	0.000
T41.0 Inhaled anaesthetics	0.008	0.991	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.008	0.991	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.008	0.991	0.000
T48.5 Anti-common-cold drugs	0.008	0.991	0.000
T48.4 Expectorants	0.008	0.991	0.000
T48.3 Antitussives	0.008	0.991	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.008	0.991	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.008	0.991	0.000
T48.0 Oxytocic drugs	0.008	0.991	0.000
T49.9 Topical agent, unspecified	0.008	0.991	0.000
T49.8 Other topical agents	0.008	0.991	0.000
T49.7 Dental drugs, topically applied	0.008	0.991	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.008	0.991	0.000
T49.5 Ophthalmological drugs and preparations	0.008	0.991	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.008	0.991	0.000
T49.3 Emollients, demulcents and protectants	0.008	0.991	0.000
T49.2 Local astringents and local detergents	0.008	0.991	0.000
T49.1 Antipruritics	0.008	0.991	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.008	0.991	0.000
O86 Other puerperal infections	0.009	0.991	0.000
I33.9 Acute endocarditis, unspecified	0.000	0.991	0.008
I36 Nonrheumatic tricuspid valve disorders	0.000	0.991	0.008
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.008	0.991	0.000
T43.2 Other and unspecified antidepressants	0.009	0.991	0.000
I34.1 Mitral (valve) prolapse	0.000	0.991	0.009
O23.5 Infections of the genital tract in pregnancy	0.008	0.991	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.008	0.991	0.000
O91.1 Abscess of breast associated with childbirth	0.008	0.992	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.008	0.992	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.008	0.992	0.000
O89.6 Failed or difficult intubation during the puerperium	0.008	0.992	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.008	0.992	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.008	0.992	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.008	0.992	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.008	0.992	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.008	0.992	0.000
C34.3 Lower lobe, bronchus or lung	0.008	0.992	0.000
O22.4 Haemorrhoids in pregnancy	0.008	0.992	0.000
T42.1 Iminostilbenes	0.008	0.992	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.008	0.992	0.000
O91.0 Infection of nipple associated with childbirth	0.008	0.992	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.992	0.008
N48.1 Balanoposthitis	0.000	0.992	0.008
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.008	0.992	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.008	0.992	0.000
T38.9 Other and unspecified hormone antagonists	0.008	0.992	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.008	0.992	0.000
T38.7 Androgens and anabolic congeners	0.008	0.992	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.008	0.992	0.000
T38.5 Other oestrogens and progestogens	0.008	0.992	0.000
T38.4 Oral contraceptives	0.008	0.992	0.000
T38.2 Antithyroid drugs	0.008	0.992	0.000
T38.1 Thyroid hormones and substitutes	0.008	0.992	0.000
T38.0 Glucocorticoids and synthetic analogues	0.008	0.992	0.000
O88.8 Other obstetric embolism	0.008	0.992	0.000
O88.3 Obstetric pyaemic and septic embolism	0.008	0.992	0.000
O88.2 Obstetric blood-clot embolism	0.008	0.992	0.000
O88.1 Amniotic fluid embolism	0.008	0.992	0.000
O88.0 Obstetric air embolism	0.008	0.992	0.000
O90.9 Complication of the puerperium, unspecified	0.008	0.992	0.000
T40.6 Other and unspecified narcotics	0.008	0.992	0.000
O12.0 Gestational oedema	0.008	0.992	0.000
T36.9 Systemic antibiotic, unspecified	0.008	0.992	0.000
T36.8 Other systemic antibiotics	0.008	0.992	0.000
T36.7 Antifungal antibiotics, systemically used	0.008	0.992	0.000
T36.6 Rifamycins	0.008	0.992	0.000
T36.5 Aminoglycosides	0.008	0.992	0.000
T36.4 Tetracyclines	0.008	0.992	0.000
T36.2 Chloramphenicol group	0.008	0.992	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.008	0.992	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.008	0.992	0.000
O97 Death from sequelae of direct obstetric causes	0.008	0.992	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.008	0.992	0.000
O95 Obstetric death of unspecified cause	0.008	0.992	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.008	0.992	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.992	0.008
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.992	0.008
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.992	0.008
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.992	0.008
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.992	0.008
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.992	0.008
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.992	0.008
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.992	0.008
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.992	0.008
I40.9 Acute myocarditis, unspecified	0.000	0.992	0.008
I40.8 Other acute myocarditis	0.000	0.992	0.008
I40.1 Isolated myocarditis	0.000	0.992	0.008
I40.0 Infective myocarditis	0.000	0.992	0.008
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.992	0.008
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.992	0.008
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.992	0.008
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.992	0.008
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.992	0.008
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.992	0.008
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.992	0.008
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.992	0.008
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.992	0.008
I48.4 Atypical atrial flutter	0.000	0.992	0.008
I48.3 Typical atrial flutter	0.000	0.992	0.008
I48.2 Chronic atrial fibrillation	0.000	0.992	0.008
I48.1 Persistent atrial fibrillation	0.000	0.992	0.008
I48.0 Paroxysmal atrial fibrillation	0.000	0.992	0.008
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.992	0.008
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.992	0.008
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.992	0.008
N35.8 Other urethral stricture	0.000	0.992	0.008
C34.1 Upper lobe, bronchus or lung	0.008	0.992	0.000
O21.9 Vomiting of pregnancy, unspecified	0.008	0.992	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.008	0.992	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.007	0.992	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.007	0.992	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.007	0.992	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.007	0.992	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.007	0.992	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.007	0.992	0.000
O90.2 Haematoma of obstetric wound	0.007	0.992	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.992	0.007
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.007	0.992	0.000
I46 Cardiac arrest	0.000	0.993	0.007
I49.3 Ventricular premature depolarisation	0.000	0.993	0.007
O21.8 Other vomiting complicating pregnancy	0.007	0.993	0.000
I44.0 Atrioventricular block, first degree	0.000	0.993	0.007
O21.2 Late vomiting of pregnancy	0.007	0.993	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.007	0.993	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
D86 Sarcoidosis	0.000	0.993	0.007
K31.7 Polyp of stomach and duodenum	0.000	0.993	0.007
C34.0 Main bronchus	0.007	0.993	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.993	0.007
H65.3 Chronic mucoid otitis media	0.007	0.993	0.000
I49.4 Other and unspecified premature depolarisation	0.000	0.993	0.007
I51 Complications and ill-defined descriptions of heart disease	0.000	0.993	0.007
D86.0 Sarcoidosis of lung	0.000	0.993	0.007
O92.7 Other and unspecified disorders of lactation	0.007	0.993	0.000
O92.6 Galactorrhoea	0.007	0.993	0.000
O92.5 Suppressed lactation	0.007	0.993	0.000
O92.4 Hypogalactia	0.007	0.993	0.000
O92.3 Agalactia	0.007	0.993	0.000
O92.0 Retracted nipple associated with childbirth	0.007	0.993	0.000
L90.5 Scar conditions and fibrosis of skin	0.000	0.993	0.007
N35.1 Postinfective urethral stricture, not elsewhere classified	0.000	0.993	0.007
N35.0 Posttraumatic urethral stricture	0.000	0.993	0.007
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.007	0.993	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.006	0.993	0.000
O92.1 Cracked nipple associated with childbirth	0.006	0.993	0.000
O86.1 Other infection of genital tract following delivery	0.006	0.993	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.993	0.007
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.007	0.993	0.000
I30.8 Other forms of acute pericarditis	0.000	0.993	0.006
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.993	0.006
I47.2 Ventricular tachycardia	0.000	0.993	0.007
R60.0 Localised oedema	0.000	0.993	0.007
G30.9 Alzheimer's disease, unspecified	0.006	0.993	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.006	0.993	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.006	0.993	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.006	0.993	0.000
O86.8 Other specified puerperal infections	0.006	0.994	0.000
O86.3 Other genito-urinary tract infections following delivery	0.006	0.994	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.994	0.006
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.994	0.006
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.994	0.006
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.994	0.006
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
T36.0 Penicillins	0.006	0.994	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.994	0.006
D86.8 Sarcoidosis of other and combined sites	0.000	0.994	0.006
O24.9 Diabetes mellitus in pregnancy, unspecified	0.006	0.994	0.000
O86.2 Urinary tract infection following delivery	0.006	0.994	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.994	0.006
L05.9 Pilonidal cyst without abscess	0.000	0.994	0.006
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.994	0.006
O21.0 Mild hyperemesis gravidarum	0.006	0.994	0.000
I30.9 Acute pericarditis, unspecified	0.000	0.994	0.006
O96.9 Death from unspecified obstetric cause	0.006	0.994	0.000
O96.1 Death from indirect obstetric cause	0.006	0.994	0.000
O96.0 Death from direct obstetric cause	0.006	0.994	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.006	0.994	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.006	0.994	0.000
O97.0 Death from sequelae of direct obstetric cause	0.006	0.994	0.000
C31 Malignant neoplasm of accessory sinuses	0.006	0.994	0.000
D86.3 Sarcoidosis of skin	0.000	0.994	0.006
I51.4 Myocarditis, unspecified	0.000	0.994	0.006
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.994	0.006
I46.1 Sudden cardiac death, so described	0.000	0.994	0.005
N48.2 Other inflammatory disorders of penis	0.000	0.994	0.006
I30.1 Infective pericarditis	0.000	0.994	0.005
O86.4 Pyrexia of unknown origin following delivery	0.005	0.994	0.000
O86.0 Infection of obstetric surgical wound	0.005	0.995	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.005	0.995	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.995	0.005
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.005	0.995	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.005	0.995	0.000
N48 Other disorders of penis	0.000	0.995	0.005
I51.6 Cardiovascular disease, unspecified	0.000	0.995	0.005
C31.0 Maxillary sinus	0.005	0.995	0.000
I51.5 Myocardial degeneration	0.000	0.995	0.005
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.995	0.005
O92.2 Other and unspecified disorders of breast associated with childbirth	0.005	0.995	0.001
I31.9 Disease of pericardium, unspecified	0.000	0.995	0.005
C37 Malignant neoplasm of thymus	0.005	0.995	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.005	0.995	0.000
C33 Malignant neoplasm of trachea	0.005	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations