TreeWAS – Variant ID: rs3808343

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000
Chapter II Neoplasms	0.999	0.001
Chapter X Diseases of the respiratory system	0.999	0.001
K20-K31 Diseases of oesophagus, stomach and duodenum	0.998	0.002
J40-J47 Chronic lower respiratory diseases	0.997	0.003
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.996	0.004
D10-D36 Benign neoplasms	0.996	0.004
K29 Gastritis and duodenitis	0.995	0.005
Chapter XII Diseases of the skin and subcutaneous tissue	0.994	0.006
J45 Asthma	0.994	0.006
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.992	0.008
J45.9 Asthma, unspecified	0.990	0.010
Chapter XXI Factors influencing health status and contact with health services	0.989	0.011
K29.7 Gastritis, unspecified	0.987	0.013
Chapter VI Diseases of the nervous system	0.981	0.019
Chapter IV Endocrine, nutritional and metabolic diseases	0.975	0.025
Chapter XIV Diseases of the genitourinary system	0.974	0.026
N30-N39 Other diseases of urinary system	0.965	0.035
N39 Other disorders of urinary system	0.962	0.038
K40-K46 Hernia	0.960	0.040
D25 Leiomyoma of uterus	0.960	0.040
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.958	0.042
L80-L99 Other disorders of the skin and subcutaneous tissue	0.956	0.044
K29.8 Duodenitis	0.955	0.045
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.955	0.045
J30-J39 Other diseases of upper respiratory tract	0.948	0.052
N39.3 Stress incontinence	0.947	0.053
G50-G59 Nerve, nerve root and plexus disorders	0.946	0.054
L00-L08 Infections of the skin and subcutaneous tissue	0.944	0.056
E70-E90 Metabolic disorders	0.938	0.062
Z40-Z54 Persons encountering health services for specific procedures and health care	0.938	0.062
K20 Oesophagitis	0.933	0.067
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.929	0.071
D25.9 Leiomyoma of uterus, unspecified	0.925	0.075
C15-C26 Malignant neoplasms of digestive organs	0.921	0.079
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.921	0.079
N39.0 Urinary tract infection, site not specified	0.916	0.084
D27 Benign neoplasm of ovary	0.912	0.088
M45-M49 Spondylopathies	0.911	0.089
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.906	0.094
K40 Inguinal hernia	0.905	0.095
M05-M14 Inflammatory polyarthropathies	0.899	0.101
Chapter I Certain infectious and parasitic diseases	0.899	0.101
Z86 Personal history of certain other diseases	0.895	0.105
D22 Melanocytic naevi	0.894	0.106
J47 Bronchiectasis	0.891	0.109
J34 Other disorders of nose and nasal sinuses	0.890	0.110
G56 Mononeuropathies of upper limb	0.886	0.114
K81 Cholecystitis	0.883	0.117
M15-M19 Arthrosis	0.879	0.121
D00-D09 In situ neoplasms	0.878	0.122
E10-E14 Diabetes mellitus	0.878	0.122
E87 Other disorders of fluid, electrolyte and acid-base balance	0.877	0.123
M50-M54 Other dorsopathies	0.872	0.128
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.872	0.128
G56.2 Lesion of ulnar nerve	0.868	0.132
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.864	0.136
S60-S69 Injuries to the wrist and hand	0.858	0.142
S00-S09 Injuries to the head	0.855	0.145
Z86.6 Personal history of diseases of the nervous system and sense organs	0.855	0.145
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.853	0.147
R20 Disturbances of skin sensation	0.853	0.147
M48 Other spondylopathies	0.852	0.148
E86 Volume depletion	0.849	0.151
K70-K77 Diseases of liver	0.848	0.152
L03 Cellulitis	0.847	0.153
Z86.4 Personal history of psychoactive substance abuse	0.845	0.155
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.844	0.156
Chapter VIII Diseases of the ear and mastoid process	0.843	0.157
S80-S89 Injuries to the knee and lower leg	0.841	0.159
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.840	0.160
K30 Dyspepsia	0.837	0.163
S50-S59 Injuries to the elbow and forearm	0.837	0.163
B95-B98 Bacterial, viral and other infectious agents	0.836	0.164
J45.0 Predominantly allergic asthma	0.836	0.164
K90-K93 Other diseases of the digestive system	0.835	0.165
G35-G37 Demyelinating diseases of the central nervous system	0.834	0.166
M51 Other intervertebral disk disorders	0.829	0.171
Chapter XV Pregnancy, childbirth and the puerperium	0.829	0.171
N10-N16 Renal tubulo-interstitial diseases	0.828	0.172
Chapter VII Diseases of the eye and adnexa	0.826	0.174
M40-M43 Deforming dorsopathies	0.826	0.174
M18 Arthrosis of first carpometacarpal joint	0.825	0.175
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.824	0.176
G58 Other mononeuropathies	0.823	0.177
K44 Diaphragmatic hernia	0.820	0.180
D17 Benign lipomatous neoplasm	0.820	0.180
S40-S49 Injuries to the shoulder and upper arm	0.819	0.181
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.819	0.181
D35 Benign neoplasm of other and unspecified endocrine glands	0.814	0.186
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.813	0.187
N17-N19 Renal failure	0.811	0.189
R73 Elevated blood glucose level	0.810	0.190
Z95 Presence of cardiac and vascular implants and grafts	0.810	0.190
D14 Benign neoplasm of middle ear and respiratory system	0.810	0.190
M48.0 Spinal stenosis	0.810	0.190
L89 Decubitus ulcer	0.809	0.190
D37-D48 Neoplasms of uncertain or unknown behaviour	0.808	0.192
M13 Other arthritis	0.808	0.192
J34.2 Deviated nasal septum	0.806	0.194
Z80 Family history of malignant neoplasm	0.805	0.195
M80-M85 Disorders of bone density and structure	0.805	0.195
K82 Other diseases of gallbladder	0.803	0.197
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.802	0.198
Z45 Adjustment and management of implanted device	0.802	0.198
E87.2 Acidosis	0.802	0.198
Z47 Other orthopaedic follow-up care	0.796	0.204
C19 Malignant neoplasm of rectosigmoid junction	0.795	0.205
K25 Gastric ulcer	0.795	0.205
L02 Cutaneous abscess, furuncle and carbuncle	0.793	0.207
R79 Other abnormal findings of blood chemistry	0.792	0.208
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.790	0.210
L85 Other epidermal thickening	0.789	0.211
R10 Abdominal and pelvic pain	0.789	0.211
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.787	0.213
R10.3 Pain localised to other parts of lower abdomen	0.787	0.213
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.787	0.213
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.787	0.213
Z50 Care involving use of rehabilitation procedures	0.786	0.214
K86 Other diseases of pancreas	0.785	0.215
E10 Insulin-dependent diabetes mellitus	0.785	0.215
K42 Umbilical hernia	0.784	0.216
D25.0 Submucous leiomyoma of uterus	0.784	0.216
D11 Benign neoplasm of major salivary glands	0.783	0.217
J00-J06 Acute upper respiratory infections	0.781	0.219
S00 Superficial injury of head	0.779	0.221
K29.6 Other gastritis	0.776	0.224
M86-M90 Other osteopathies	0.775	0.225
J34.8 Other specified disorders of nose and nasal sinuses	0.775	0.225
K81.9 Cholecystitis, unspecified	0.774	0.226
J80-J84 Other respiratory diseases principally affecting the interstitium	0.773	0.227
Z95.5 Presence of coronary angioplasty implant and graft	0.772	0.228
E83 Disorders of mineral metabolism	0.772	0.228
C20 Malignant neoplasm of rectum	0.772	0.228
E87.5 Hyperkalaemia	0.771	0.229
L40-L45 Papulosquamous disorders	0.771	0.229
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.771	0.229
J40 Bronchitis, not specified as acute or chronic	0.770	0.230
D10 Benign neoplasm of mouth and pharynx	0.769	0.231
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.768	0.232
L20-L30 Dermatitis and eczema	0.767	0.232
Z41 Procedures for purposes other than remedying health state	0.767	0.233
L03.3 Cellulitis of trunk	0.767	0.233
S70-S79 Injuries to the hip and thigh	0.767	0.233
R21 Rash and other nonspecific skin eruption	0.766	0.234
C51-C58 Malignant neoplasms of female genital organs	0.763	0.237
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.762	0.238
S90-S99 Injuries to the ankle and foot	0.762	0.238
M65-M68 Disorders of synovium and tendon	0.762	0.238
L50-L54 Urticaria and erythema	0.762	0.238
M18.1 Other primary arthrosis of first carpometacarpal joint	0.761	0.239
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.760	0.240
D04 Carcinoma in situ of skin	0.760	0.240
E50-E64 Other nutritional deficiencies	0.759	0.241
Z48 Other surgical follow-up care	0.757	0.243
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.757	0.243
K29.0 Acute haemorrhagic gastritis	0.755	0.245
J46 Status asthmaticus	0.755	0.245
Z96 Presence of other functional implants	0.755	0.245
L81 Other disorders of pigmentation	0.755	0.245
L92 Granulomatous disorders of skin and subcutaneous tissue	0.754	0.246
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.753	0.247
R15 Faecal incontinence	0.753	0.247
K35-K38 Diseases of appendix	0.752	0.248
D22.7 Melanocytic naevi of lower limb, including hip	0.750	0.250
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.749	0.251
J38.3 Other diseases of vocal cords	0.749	0.251
T66-T78 Other and unspecified effects of external causes	0.749	0.251
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.748	0.251
R23 Other skin changes	0.748	0.252
R20.2 Paraesthesia of skin	0.748	0.252
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.747	0.253
N60-N64 Disorders of breast	0.746	0.254
N00-N08 Glomerular diseases	0.745	0.255
D22.0 Melanocytic naevi of lip	0.743	0.257
M13.9 Arthritis, unspecified	0.742	0.258
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.741	0.259
M48.06 Spinal stenosis (Lumbar region)	0.741	0.259
N35 Urethral stricture	0.737	0.263
L08 Other local infections of skin and subcutaneous tissue	0.737	0.263
M51.2 Other specified intervertebral disk displacement	0.736	0.264
J95-J99 Other diseases of the respiratory system	0.736	0.264
G58.9 Mononeuropathy, unspecified	0.736	0.264
G20-G26 Extrapyramidal and movement disorders	0.735	0.265
Z43 Attention to artificial openings	0.733	0.267
K55-K64 Other diseases of intestines	0.733	0.267
K81.0 Acute cholecystitis	0.732	0.268
Z80.3 Family history of malignant neoplasm of breast	0.732	0.268
G35 Multiple sclerosis	0.729	0.271
R20.8 Other and unspecified disturbances of skin sensation	0.728	0.272
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.728	0.272
H43-H45 Disorders of vitreous body and globe	0.727	0.273
E20-E35 Disorders of other endocrine glands	0.727	0.273
S52 Fracture of forearm	0.726	0.274
Chapter XXII Codes for special purposes	0.726	0.274
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.726	0.274
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.725	0.275
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.725	0.275
S20-S29 Injuries to the thorax	0.724	0.276
Z52 Donors of organs and tissues	0.724	0.276
Z89 Acquired absence of limb	0.723	0.276
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.723	0.277
O60-O75 Complications of labour and delivery	0.722	0.278
K83 Other diseases of biliary tract	0.722	0.278
Z40 Prophylactic surgery	0.721	0.279
L05 Pilonidal cyst	0.721	0.279
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.720	0.280
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.718	0.282
H25-H28 Disorders of lens	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.716	0.283
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.716	0.283
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.716	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.283
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.716	0.284
K28 Gastrojejunal ulcer	0.716	0.284
K23 Disorders of oesophagus in diseases classified elsewhere	0.716	0.284
J41 Simple and mucopurulent chronic bronchitis	0.714	0.285
J42 Unspecified chronic bronchitis	0.714	0.285
M91-M94 Chondropathies	0.714	0.286
M60-M63 Disorders of muscles	0.714	0.286
M00-M03 Infectious arthropathies	0.714	0.286
D31 Benign neoplasm of eye and adnexa	0.714	0.286
D30 Benign neoplasm of urinary organs	0.714	0.286
D29 Benign neoplasm of male genital organs	0.714	0.286
D28 Benign neoplasm of other and unspecified female genital organs	0.714	0.286
D26 Other benign neoplasms of uterus	0.714	0.286
D21 Other benign neoplasms of connective and other soft tissue	0.714	0.286
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.714	0.286
D19 Benign neoplasm of mesothelial tissue	0.714	0.286
D16 Benign neoplasm of bone and articular cartilage	0.714	0.286
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.714	0.286
D34 Benign neoplasm of thyroid gland	0.714	0.286
C25 Malignant neoplasm of pancreas	0.714	0.286
N39.4 Other specified urinary incontinence	0.714	0.286
N36 Other disorders of urethra	0.714	0.286
K29.9 Gastroduodenitis, unspecified	0.713	0.286
K29.3 Chronic superficial gastritis	0.713	0.286
K29.2 Alcoholic gastritis	0.713	0.286
D33 Benign neoplasm of brain and other parts of central nervous system	0.713	0.287
L10-L14 Bullous disorders	0.713	0.287
J45.8 Mixed asthma	0.712	0.287
J45.1 Nonallergic asthma	0.712	0.287
R73.9 Hyperglycaemia, unspecified	0.712	0.288
Z88.0 Personal history of allergy to penicillin	0.712	0.288
M19 Other arthrosis	0.712	0.288
L03.0 Cellulitis of finger and toe	0.711	0.289
T79-T79 Certain early complications of trauma	0.711	0.289
T33-T35 Frostbite	0.711	0.289
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.711	0.289
T26-T28 Burns and corrosions confined to eye and internal organs	0.711	0.289
T20-T25 Burns and corrosions of external body surface, specified by site	0.711	0.289
T15-T19 Effects of foreign body entering through natural orifice	0.711	0.289
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.711	0.289
T00-T07 Injuries involving multiple body regions	0.711	0.289
S10-S19 Injuries to the neck	0.711	0.289
G30-G32 Other degenerative diseases of the nervous system	0.711	0.289
E11 Non-insulin-dependent diabetes mellitus	0.710	0.290
K27 Peptic ulcer, site unspecified	0.708	0.292
G50 Disorders of trigeminal nerve	0.708	0.292
M51.9 Intervertebral disk disorder, unspecified	0.707	0.293
D25.2 Subserosal leiomyoma of uterus	0.707	0.293
N39.9 Disorder of urinary system, unspecified	0.705	0.295
K59 Other functional intestinal disorders	0.705	0.295
L90 Atrophic disorders of skin	0.704	0.296
M43 Other deforming dorsopathies	0.704	0.296
D12.5 Sigmoid colon	0.704	0.296
N17 Acute renal failure	0.704	0.296
G70-G73 Diseases of myoneural junction and muscle	0.704	0.296
G00-G09 Inflammatory diseases of the central nervous system	0.704	0.296
J09-J18 Influenza and pneumonia	0.703	0.297
R10.2 Pelvic and perineal pain	0.702	0.298
J60-J70 Lung diseases due to external agents	0.701	0.299
K26 Duodenal ulcer	0.701	0.299
M10 Gout	0.701	0.299
D22.6 Melanocytic naevi of upper limb, including shoulder	0.700	0.300
G51 Facial nerve disorders	0.700	0.300
H90-H95 Other disorders of ear	0.699	0.301
B35-B49 Mycoses	0.699	0.301
E40-E46 Malnutrition	0.699	0.301
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.698	0.302
D36 Benign neoplasm of other and unspecified sites	0.698	0.302
J32 Chronic sinusitis	0.698	0.302
Z95.0 Presence of cardiac pacemaker	0.697	0.303
E83.1 Disorders of iron metabolism	0.696	0.304
C64-C68 Malignant neoplasms of urinary tract	0.695	0.305
K74 Fibrosis and cirrhosis of liver	0.695	0.305
G59 Mononeuropathy in diseases classified elsewhere	0.695	0.305
L89.9 Decubitus ulcer and pressure area, unspecified	0.695	0.305
K92 Other diseases of digestive system	0.695	0.305
B25-B34 Other viral diseases	0.694	0.305
Z70-Z76 Persons encountering health services in other circumstances	0.694	0.306
G80-G83 Cerebral palsy and other paralytic syndromes	0.694	0.306
D22.5 Melanocytic naevi of trunk	0.693	0.307
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.693	0.307
L60-L75 Disorders of skin appendages	0.692	0.308
N37 Urethral disorders in diseases classified elsewhere	0.692	0.308
N34 Urethritis and urethral syndrome	0.692	0.308
N33 Bladder disorders in diseases classified elsewhere	0.692	0.308
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.692	0.308
E87.0 Hyperosmolality and hypernatraemia	0.690	0.310
N39.2 Orthostatic proteinuria, unspecified	0.690	0.310
N39.1 Persistent proteinuria, unspecified	0.690	0.310
R79.8 Other specified abnormal findings of blood chemistry	0.689	0.311
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.689	0.311
L98.8 Other specified disorders of skin and subcutaneous tissue	0.688	0.311
K46 Unspecified abdominal hernia	0.688	0.312
K45 Other abdominal hernia	0.688	0.312
C16 Malignant neoplasm of stomach	0.688	0.312
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.687	0.313
R95-R99 Ill-defined and unknown causes of mortality	0.687	0.313
K81.1 Chronic cholecystitis	0.686	0.314
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.685	0.315
L95 Vasculitis limited to skin, not elsewhere classified	0.685	0.315
L94 Other localised connective tissue disorders	0.685	0.315
L93 Lupus erythematosus	0.685	0.315
L87 Transepidermal elimination disorders	0.685	0.315
L88 Pyoderma gangrenosum	0.685	0.315
L86 Keratoderma in diseases classified elsewhere	0.685	0.315
L84 Corns and callosities	0.685	0.315
L83 Acanthosis nigricans	0.685	0.315
L80 Vitiligo	0.685	0.315
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.685	0.315
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.685	0.315
D35.1 Parathyroid gland	0.684	0.316
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.684	0.316
M05 Seropositive rheumatoid arthritis	0.683	0.317
R74 Abnormal serum enzyme levels	0.683	0.317
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.683	0.317
H65-H75 Diseases of middle ear and mastoid	0.682	0.318
G90-G99 Other disorders of the nervous system	0.682	0.318
N99-N99 Other disorders of the genitourinary system	0.681	0.318
S00.9 Superficial injury of head, part unspecified	0.682	0.318
L98.0 Pyogenic granuloma	0.681	0.319
M46 Other inflammatory spondylopathies	0.681	0.319
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.681	0.319
S82 Fracture of lower leg, including ankle	0.681	0.319
J37 Chronic laryngitis and laryngotracheitis	0.679	0.321
D32 Benign neoplasm of meninges	0.679	0.321
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.679	0.321
G54 Nerve root and plexus disorders	0.678	0.322
G53 Cranial nerve disorders in diseases classified elsewhere	0.678	0.322
G52 Disorders of other cranial nerves	0.678	0.322
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.678	0.322
K50-K52 Noninfective enteritis and colitis	0.678	0.322
L04 Acute lymphadenitis	0.677	0.323
L01 Impetigo	0.677	0.323
L00 Staphylococcal scalded skin syndrome	0.677	0.323
D14.1 Larynx	0.677	0.323
Z91 Personal history of risk-factors, not elsewhere classified	0.676	0.324
D18 Haemangioma and lymphangioma, any site	0.676	0.324
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.675	0.325
M13.90 Arthritis, unspecified (Multiple sites)	0.674	0.326
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.674	0.326
R27 Other lack of coordination	0.673	0.327
S02 Fracture of skull and facial bones	0.672	0.327
E88 Other metabolic disorders	0.672	0.328
E85 Amyloidosis	0.672	0.328
E84 Cystic fibrosis	0.672	0.328
E80 Disorders of porphyrin and bilirubin metabolism	0.672	0.328
E79 Disorders of purine and pyrimidine metabolism	0.672	0.328
E77 Disorders of glycoprotein metabolism	0.672	0.328
E76 Disorders of glycosaminoglycan metabolism	0.672	0.328
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.672	0.328
E74 Other disorders of carbohydrate metabolism	0.672	0.328
E73 Lactose intolerance	0.672	0.328
E72 Other disorders of amino-acid metabolism	0.672	0.328
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.672	0.328
E70 Disorders of aromatic amino-acid metabolism	0.672	0.328
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.672	0.328
Z97 Presence of other devices	0.672	0.328
Z54 Convalescence	0.672	0.328
Z49 Care involving dialysis	0.672	0.328
Z44 Fitting and adjustment of external prosthetic device	0.672	0.328
K29.4 Chronic atrophic gastritis	0.671	0.328
K59.0 Constipation	0.672	0.328
H25 Senile cataract	0.671	0.329
Z00-Z13 Persons encountering health services for examination and investigation	0.671	0.329
S60 Superficial injury of wrist and hand	0.671	0.329
Z39 Postpartum care and examination	0.670	0.330
N80-N98 Noninflammatory disorders of female genital tract	0.669	0.331
G63 Polyneuropathy in diseases classified elsewhere	0.668	0.332
K29.1 Other acute gastritis	0.667	0.332
J39 Other diseases of upper respiratory tract	0.666	0.333
N39.8 Other specified disorders of urinary system	0.665	0.335
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.665	0.335
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.665	0.335
L91 Hypertrophic disorders of skin	0.664	0.336
D05 Carcinoma in situ of breast	0.664	0.336
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.664	0.336
K65-K67 Diseases of peritoneum	0.663	0.337
K75 Other inflammatory liver diseases	0.662	0.338
S69 Other and unspecified injuries of wrist and hand	0.662	0.338
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.661	0.339
B15-B19 Viral hepatitis	0.661	0.339
Z37 Outcome of delivery	0.661	0.339
C26 Malignant neoplasm of other and ill-defined digestive organs	0.660	0.340
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.660	0.340
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.660	0.340
C21 Malignant neoplasm of anus and anal canal	0.660	0.340
C17 Malignant neoplasm of small intestine	0.660	0.340
C23 Malignant neoplasm of gallbladder	0.660	0.340
Z84 Family history of other conditions	0.660	0.340
Z81 Family history of mental and behavioural disorders	0.660	0.340
D06 Carcinoma in situ of cervix uteri	0.660	0.340
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.660	0.340
S64 Injury of nerves at wrist and hand level	0.660	0.340
L03.8 Cellulitis of other sites	0.659	0.340
Z83 Family history of other specific disorders	0.659	0.340
K82.4 Cholesterolosis of gallbladder	0.659	0.341
J30 Vasomotor and allergic rhinitis	0.659	0.341
Z45.0 Adjustment and management of cardiac pacemaker	0.659	0.341
N13 Obstructive and reflux uropathy	0.658	0.342
K90 Intestinal malabsorption	0.657	0.343
C18 Malignant neoplasm of colon	0.657	0.343
M48.02 Spinal stenosis (Cervical region)	0.657	0.343
L85.9 Epidermal thickening, unspecified	0.656	0.344
G57 Mononeuropathies of lower limb	0.656	0.344
B97 Viral agents as the cause of diseases classified to other chapters	0.656	0.344
D23 Other benign neoplasms of skin	0.656	0.344
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.655	0.345
J36 Peritonsillar abscess	0.655	0.345
L97 Ulcer of lower limb, not elsewhere classified	0.655	0.345
O00-O08 Pregnancy with abortive outcome	0.654	0.346
Chapter XX External causes of morbidity and mortality	0.653	0.346
M49 Spondylopathies in diseases classified elsewhere	0.653	0.347
M45 Ankylosing spondylitis	0.653	0.347
J20-J22 Other acute lower respiratory infections	0.653	0.347
E87.7 Fluid overload	0.652	0.348
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.652	0.348
K85 Acute pancreatitis	0.651	0.348
S52.5 Fracture of lower end of radius	0.651	0.348
D03 Melanoma in situ	0.651	0.349
Chapter IX Diseases of the circulatory system	0.651	0.349
O80-O84 Delivery	0.650	0.350
K22 Other diseases of oesophagus	0.650	0.350
R78 Findings of drugs and other substances, not normally found in blood	0.650	0.350
R77 Other abnormalities of plasma proteins	0.650	0.350
R76 Other abnormal immunological findings in serum	0.650	0.350
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.650	0.350
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.650	0.350
R72 Abnormality of white blood cells, not elsewhere classified	0.650	0.350
R71 Abnormality of red blood cells	0.650	0.350
Z45.1 Adjustment and management of infusion pump	0.649	0.350
Z80.5 Family history of malignant neoplasm of urinary tract	0.649	0.351
R73.0 Abnormal glucose tolerance test	0.649	0.351
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.649	0.351
T93 Sequelae of injuries of lower limb	0.649	0.351
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.649	0.351
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.649	0.351
K40.1 Bilateral inguinal hernia, with gangrene	0.649	0.351
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.649	0.351
Z36 Antenatal screening	0.649	0.351
D45 Polycythaemia vera	0.648	0.352
N70-N77 Inflammatory diseases of female pelvic organs	0.648	0.352
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.647	0.353
K82.1 Hydrops of gallbladder	0.646	0.354
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.646	0.354
K41 Femoral hernia	0.645	0.355
Z48.9 Surgical follow-up care, unspecified	0.645	0.355
M14 Arthropathies in other diseases classified elsewhere	0.645	0.355
M12 Other specific arthropathies	0.645	0.355
M09 Juvenile arthritis in diseases classified elsewhere	0.645	0.355
M08 Juvenile arthritis	0.645	0.355
M07 Psoriatic and enteropathic arthropathies	0.645	0.355
M11 Other crystal arthropathies	0.645	0.355
B99-B99 Other infectious diseases	0.645	0.355
B90-B94 Sequelae of infectious and parasitic diseases	0.645	0.355
B85-B89 Pediculosis, acariasis and other infestations	0.645	0.355
B65-B83 Helminthiases	0.645	0.355
B50-B64 Protozoal diseases	0.645	0.355
B20-B24 Human immunodeficiency virus [HIV] disease	0.645	0.355
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.645	0.355
A80-A89 Viral infections of the central nervous system	0.645	0.355
A75-A79 Rickettsioses	0.645	0.355
A70-A74 Other diseases caused by chlamydiae	0.645	0.355
A65-A69 Other spirochaetal diseases	0.645	0.355
A50-A64 Infections with a predominantly sexual mode of transmission	0.645	0.355
A20-A28 Certain zoonotic bacterial diseases	0.645	0.355
A15-A19 Tuberculosis	0.645	0.355
K70 Alcoholic liver disease	0.644	0.356
R26 Abnormalities of gait and mobility	0.643	0.357
Z88.3 Personal history of allergy to other anti-infective agents	0.643	0.357
E10.1 With ketoacidosis	0.643	0.357
Z42 Follow-up care involving plastic surgery	0.642	0.358
D12.2 Ascending colon	0.642	0.358
J33 Nasal polyp	0.642	0.358
D04.7 Skin of lower limb, including hip	0.642	0.358
D22.9 Melanocytic naevi, unspecified	0.641	0.359
D22.4 Melanocytic naevi of scalp and neck	0.641	0.359
D22.2 Melanocytic naevi of ear and external auricular canal	0.641	0.359
D22.1 Melanocytic naevi of eyelid, including canthus	0.641	0.359
T90 Sequelae of injuries of head	0.641	0.359
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.641	0.359
K72 Hepatic failure, not elsewhere classified	0.640	0.360
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.640	0.360
S42 Fracture of shoulder and upper arm	0.640	0.360
M13.97 Arthritis, unspecified (Ankle and foot)	0.640	0.360
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.639	0.361

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations