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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3817969
log Bayes Factor = 77.685
Chromosome 6   position 32,361,388  (GRCh37) Explore rs3817969 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
E10.9 Without complications
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
C44.7 Skin of lower limb, including hip
1.000 0.000 0.000
K50-K52 Noninfective enteritis and colitis
0.999 0.001 0.000
K50 Crohn's disease [regional enteritis]
0.999 0.001 0.000
K50.1 Crohn's disease of large intestine
0.999 0.001 0.000
C44.4 Skin of scalp and neck
0.996 0.004 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.006 0.994
D86 Sarcoidosis
0.000 0.007 0.993
Z93.2 Ileostomy status
0.993 0.007 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.991 0.009 0.000
K51.4 Pseudopolyposis of colon
0.990 0.010 0.000
E10.1 With ketoacidosis
0.000 0.010 0.990
E10.3 With ophthalmic complications
0.000 0.012 0.988
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.985 0.015 0.000
D86.0 Sarcoidosis of lung
0.000 0.017 0.983
C44.2 Skin of ear and external auricular canal
0.980 0.020 0.000
C44.5 Skin of trunk
0.978 0.022 0.000
C44.6 Skin of upper limb, including shoulder
0.973 0.027 0.000
C44.0 Skin of lip
0.960 0.040 0.000
K51.8 Other ulcerative colitis
0.959 0.041 0.000
K51.2 Ulcerative (chronic) proctitis
0.951 0.049 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.948 0.052 0.000
K50.9 Crohn's disease, unspecified
0.929 0.071 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.926 0.074 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.923 0.077 0.000
C83.3 Large cell (diffuse)
0.918 0.082 0.000
E10-E14 Diabetes mellitus
0.000 0.083 0.917
D86.8 Sarcoidosis of other and combined sites
0.000 0.085 0.915
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.908 0.092 0.000
C82.0 Small cleaved cell, follicular
0.906 0.094 0.000
D86.1 Sarcoidosis of lymph nodes
0.000 0.104 0.896
E16.2 Hypoglycaemia, unspecified
0.000 0.111 0.889
E16 Other disorders of pancreatic internal secretion
0.000 0.111 0.889
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.113 0.887
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.113 0.887
D51 Vitamin B12 deficiency anaemia
0.000 0.135 0.865
D50-D53 Nutritional anaemias
0.000 0.136 0.864
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.140 0.860
D80-D89 Certain disorders involving the immune mechanism
0.000 0.148 0.851
K52 Other non-infective gastro-enteritis and colitis
0.848 0.152 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.154 0.846
D50 Iron deficiency anaemia
0.000 0.155 0.845
D50.9 Iron deficiency anaemia, unspecified
0.000 0.155 0.845
K51.5 Mucosal proctocolitis
0.844 0.156 0.000
E10.8 With unspecified complications
0.000 0.159 0.841
E27 Other disorders of adrenal gland
0.000 0.164 0.836
E27.1 Primary adrenocortical insufficiency
0.000 0.167 0.833
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.170 0.830
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.827 0.173 0.000
K90 Intestinal malabsorption
0.000 0.184 0.816
C44.1 Skin of eyelid, including canthus
0.799 0.201 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.205 0.795
C82.3 Follicular lymphoma grade IIIa
0.794 0.206 0.000
E10.4 With neurological complications
0.000 0.224 0.776
E10.0 With coma
0.000 0.227 0.773
E22 Hyperfunction of pituitary gland
0.000 0.227 0.773
C44.9 Malignant neoplasm of skin, unspecified
0.767 0.233 0.000
E10.6 With other specified complications
0.000 0.247 0.753
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.251 0.749
K52.8 Other specified non-infective gastro-enteritis and colitis
0.749 0.251 0.000
K50.8 Other Crohn's disease
0.745 0.255 0.000
K52.1 Toxic gastro-enteritis and colitis
0.742 0.258 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.737 0.263 0.000
C83.1 Small cleaved cell (diffuse)
0.732 0.268 0.000
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E16.1 Other hypoglycaemia
0.000 0.284 0.716
C81 Hodgkin's disease
0.713 0.287 0.000
D86.3 Sarcoidosis of skin
0.000 0.288 0.712
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.288 0.712
K51.0 Ulcerative (chronic) enterocolitis
0.712 0.288 0.000
E10.2 With renal complications
0.000 0.288 0.712
C82.2 Large cell, follicular
0.710 0.290 0.000
C82.6 Cutaneous follicle centre lymphoma
0.706 0.294 0.000
C82.5 Diffuse follicle centre lymphoma
0.706 0.294 0.000
C82.4 Follicular lymphoma grade IIIb
0.706 0.294 0.000
K52.3 Indeterminate colitis
0.705 0.295 0.000
C85.1 B-cell lymphoma, unspecified
0.700 0.300 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.699 0.301 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.308 0.692
E14 Unspecified diabetes mellitus
0.000 0.313 0.687
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.314 0.685
E13 Other specified diabetes mellitus
0.000 0.319 0.681
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.680 0.320 0.000
C94 Other leukaemias of specified cell type
0.680 0.320 0.000
C93 Monocytic leukaemia
0.680 0.320 0.000
C86 Other specified types of T/NK-cell lymphoma
0.680 0.320 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.678 0.322 0.000
D52 Folate deficiency anaemia
0.000 0.325 0.675
C95 Leukaemia of unspecified cell type
0.671 0.329 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.666 0.334 0.000
C83.6 Undifferentiated (diffuse)
0.664 0.336 0.000
C83.5 Lymphoblastic (diffuse)
0.664 0.336 0.000
C83.4 Immunoblastic (diffuse)
0.664 0.336 0.000
C83.2 Mixed small and large cell (diffuse)
0.664 0.336 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.662 0.338 0.000
C85.0 Lymphosarcoma
0.662 0.338 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.338 0.662
E24 Cushing's syndrome
0.000 0.342 0.658
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.342 0.658
E27.2 Addisonian crisis
0.000 0.342 0.658
E12 Malnutrition-related diabetes mellitus
0.000 0.342 0.657
K90.9 Intestinal malabsorption, unspecified
0.000 0.347 0.653
E10.5 With peripheral circulatory complications
0.000 0.357 0.643
K51.1 Ulcerative (chronic) ileocolitis
0.641 0.359 0.000
C83.7 Burkitt's tumour
0.638 0.362 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.363 0.637
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.363 0.637
E16.4 Abnormal secretion of gastrin
0.000 0.363 0.637
E16.3 Increased secretion of glucagon
0.000 0.363 0.637
E15 Nondiabetic hypoglycaemic coma
0.000 0.364 0.636
C90 Multiple myeloma and malignant plasma cell neoplasms
0.620 0.380 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.380 0.620
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.380 0.620
D51.2 Transcobalamin II deficiency
0.000 0.380 0.620
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.380 0.620
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.619 0.381 0.000
K90.8 Other intestinal malabsorption
0.000 0.383 0.617
E22.1 Hyperprolactinaemia
0.000 0.383 0.617
E20 Hypoparathyroidism
0.000 0.389 0.611
D82 Immunodeficiency associated with other major defects
0.000 0.389 0.610
D81 Combined immunodeficiencies
0.000 0.389 0.610
C88 Malignant immunoproliferative diseases
0.610 0.390 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.393 0.606
E32 Diseases of thymus
0.000 0.393 0.606
E31 Polyglandular dysfunction
0.000 0.393 0.606
E30 Disorders of puberty, not elsewhere classified
0.000 0.393 0.606
E25 Adrenogenital disorders
0.000 0.393 0.606
D50.1 Sideropenic dysphagia
0.000 0.394 0.606
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.399 0.601
E27.5 Adrenomedullary hyperfunction
0.000 0.400 0.600
E27.0 Other adrenocortical overactivity
0.000 0.400 0.600
D53 Other nutritional anaemias
0.000 0.402 0.598
C81.1 Nodular sclerosis
0.587 0.413 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.415 0.585
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.415 0.585
K90.1 Tropical sprue
0.000 0.415 0.585
E22.0 Acromegaly and pituitary gigantism
0.000 0.427 0.573
E40-E46 Malnutrition
0.000 0.428 0.571
E14.9 Without complications
0.000 0.432 0.568
C85.7 Other specified types of non-Hodgkin's lymphoma
0.560 0.440 0.000
E34 Other endocrine disorders
0.000 0.444 0.556
E27.8 Other specified disorders of adrenal gland
0.000 0.446 0.554
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.446 0.554
E22.8 Other hyperfunction of pituitary gland
0.000 0.446 0.554
D55-D59 Haemolytic anaemias
0.000 0.447 0.553
C81.2 Mixed cellularity
0.543 0.457 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.540 0.460 0.000
D52.9 Folate deficiency anaemia, unspecified
0.000 0.460 0.540
C81.0 Lymphocytic predominance
0.538 0.461 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.537 0.462 0.000
E21.0 Primary hyperparathyroidism
0.000 0.464 0.536
D83 Common variable immunodeficiency
0.000 0.466 0.534
E24.9 Cushing's syndrome, unspecified
0.000 0.476 0.524
D80 Immunodeficiency with predominantly antibody defects
0.000 0.477 0.523
E65-E68 Obesity and other hyperalimentation
0.000 0.477 0.523
C95.0 Acute leukaemia of unspecified cell type
0.521 0.479 0.000
E00-E07 Disorders of thyroid gland
0.000 0.479 0.521
E14.3 With ophthalmic complications
0.000 0.487 0.513
E13.9 Without complications
0.000 0.488 0.512
C81.7 Other Hodgkin's disease
0.511 0.489 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.511 0.489 0.000
C81.3 Lymphocytic depletion
0.511 0.489 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.491 0.508
E29 Testicular dysfunction
0.000 0.493 0.507
C84.0 Mycosis fungoides
0.500 0.500 0.000
D84 Other immunodeficiencies
0.001 0.506 0.494
E14.8 With unspecified complications
0.000 0.507 0.493
E14.7 With multiple complications
0.000 0.507 0.493
E14.2 Withrenal complications
0.000 0.507 0.493
E14.1 With ketoacidosis
0.000 0.507 0.493
E14.0 With coma
0.000 0.507 0.493
C84.4 Peripheral T-cell lymphoma
0.490 0.510 0.000
E13.8 With unspecified complications
0.000 0.511 0.488
E13.7 With multiple complications
0.000 0.511 0.488
E13.6 With other specified complications
0.000 0.511 0.488
E13.5 With peripheral circulatory complications
0.000 0.511 0.488
E13.4 With neurological complications
0.000 0.511 0.488
E13.3 With ophthalmic complications
0.000 0.511 0.488
E13.2 With renal complications
0.000 0.511 0.488
E13.1 With ketoacidosis
0.000 0.511 0.488
E13.0 With coma
0.000 0.511 0.488
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.487 0.512 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.487 0.512 0.000
C86.4 Blastic NK-cell lymphoma
0.487 0.512 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.487 0.512 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.487 0.512 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.487 0.512 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.487 0.512 0.000
C93.9 Monocytic leukaemia, unspecified
0.487 0.512 0.000
C93.7 Other monocytic leukaemia
0.487 0.512 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.487 0.512 0.000
C93.2 Subacute monocytic leukaemia
0.487 0.512 0.000
C93.1 Chronic monocytic leukaemia
0.487 0.512 0.000
C93.0 Acute monocytic leukaemia
0.487 0.512 0.000
C94.7 Other specified leukaemias
0.487 0.512 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.487 0.512 0.000
C94.5 Acute myelofibrosis
0.487 0.512 0.000
C94.4 Acute panmyelosis
0.487 0.512 0.000
C94.3 Mast cell leukaemia
0.487 0.512 0.000
C94.2 Acute megakaryoblastic leukaemia
0.487 0.512 0.000
C94.1 Chronic erythraemia
0.487 0.512 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.487 0.512 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.487 0.512 0.000
C96.8 Histiocytic sarcoma
0.487 0.512 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.487 0.512 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.487 0.512 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.487 0.512 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.487 0.512 0.000
C96.3 True histiocytic lymphoma
0.487 0.512 0.000
C96.2 Malignant mast cell tumour
0.487 0.512 0.000
C96.1 Malignant histiocytosis
0.487 0.512 0.000
C96.0 Letterer-Siwe disease
0.487 0.512 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.486 0.514 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.486 0.514 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.486 0.514 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.486 0.514 0.000
C84.3 Lymphoepithelioid lymphoma
0.486 0.514 0.000
C84.2 T-zone lymphoma
0.486 0.514 0.000
C84.1 Sezary's diease
0.486 0.514 0.000
D52.8 Other folate deficiency anaemias
0.000 0.516 0.484
D52.1 Drug-induced folate deficiency anaemia
0.000 0.516 0.484
D52.0 Dietary folate deficiency anaemia
0.000 0.516 0.484
C95.7 Other leukaemia of unspecified cell type
0.481 0.519 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.481 0.519 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.481 0.519 0.000
E14.6 With other specified complications
0.000 0.523 0.476
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.526 0.474
E21.4 Other specified disorders of parathyroid gland
0.000 0.526 0.474
E21.2 Other hyperparathyroidism
0.000 0.526 0.474
E24.8 Other Cushing's syndrome
0.000 0.528 0.472
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.528 0.472
E24.3 Ectopic ACTH syndrome
0.000 0.528 0.472
E24.2 Drug-induced Cushing's syndrome
0.000 0.528 0.472
E24.1 Nelson's syndrome
0.000 0.528 0.472
E24.0 Pituitary-dependent Cushing's disease
0.000 0.528 0.472
E14.5 With peripheral circulatory complications
0.000 0.528 0.472
E12.9 Without complications
0.000 0.528 0.471
E12.8 With unspecified complications
0.000 0.528 0.471
E12.7 With multiple complications
0.000 0.528 0.471
E12.6 With other specified complications
0.000 0.528 0.471
E12.5 With peripheral circulatory complications
0.000 0.528 0.471
E12.4 With neurological complications
0.000 0.528 0.471
E12.3 With ophthalmic complications
0.000 0.528 0.471
E12.2 With renal complications
0.000 0.528 0.471
E12.1 With ketoacidosis
0.000 0.528 0.471
E12.0 With coma
0.000 0.528 0.471
C84.5 Other and unspecified T-cell lymphomas
0.465 0.534 0.000
E50-E64 Other nutritional deficiencies
0.000 0.535 0.465
E03 Other hypothyroidism
0.000 0.536 0.463
K52.0 Gastro-enteritis and colitis due to radiation
0.463 0.537 0.000
E34.0 Carcinoid syndrome
0.000 0.537 0.463
D59 Acquired haemolytic anaemia
0.000 0.546 0.454
C90.0 Multiple myeloma
0.445 0.555 0.000
C90.3 Solitary plasmacytoma
0.445 0.555 0.000
C90.1 Plasma cell leukaemia
0.445 0.555 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.557 0.443
C91 Lymphoid leukaemia
0.440 0.559 0.001
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.559 0.441
E14.4 With neurological complications
0.000 0.561 0.439
E20.8 Other hypoparathyroidism
0.000 0.562 0.438
E20.1 Pseudohypoparathyroidism
0.000 0.562 0.438
E20.0 Idiopathic hypoparathyroidism
0.000 0.562 0.438
D81.9 Combined immunodeficiency, unspecified
0.000 0.562 0.438
D81.8 Other combined immunodeficiencies
0.000 0.562 0.438
D81.7 Major histocompatibility complex class II deficiency
0.000 0.562 0.438
D81.6 Major histocompatibility complex class I deficiency
0.000 0.562 0.438
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.562 0.438
D81.4 Nezelof's syndrome
0.000 0.562 0.438
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.562 0.438
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.562 0.438
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.562 0.438
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.562 0.438
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.562 0.438
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.562 0.438
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.562 0.438
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.562 0.438
D82.2 Immunodeficiency with short-limbed stature
0.000 0.562 0.438
D82.1 Di George's syndrome
0.000 0.562 0.438
D82.0 Wiskott-Aldrich syndrome
0.000 0.562 0.438
C88.9 Malignant immunoproliferative disease, unspecified
0.437 0.563 0.000
C88.7 Other malignant immunoproliferative diseases
0.437 0.563 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.437 0.563 0.000
C88.3 Immunoproliferative small intestinal disease
0.437 0.563 0.000
C88.2 Gamma heavy chain disease
0.437 0.563 0.000
C88.1 Alpha heavy chain disease
0.437 0.563 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.565 0.435
E25.8 Other adrenogenital disorders
0.000 0.565 0.435
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.565 0.435
E30.9 Disorder of puberty, unspecified
0.000 0.565 0.435
E30.8 Other disorders of puberty
0.000 0.565 0.435
E30.1 Precocious puberty
0.000 0.565 0.435
E30.0 Delayed puberty
0.000 0.565 0.435
E31.9 Polyglandular dysfunction, unspecified
0.000 0.565 0.435
E31.8 Other polyglandular dysfunction
0.000 0.565 0.435
E31.1 Polyglandular hyperfunction
0.000 0.565 0.435
E31.0 Autoimmune polyglandular failure
0.000 0.565 0.435
E32.9 Disease of thymus, unspecified
0.000 0.565 0.435
E32.8 Other diseases of thymus
0.000 0.565 0.435
E32.1 Abscess of thymus
0.000 0.565 0.435
E32.0 Persistent hyperplasia of thymus
0.000 0.565 0.435
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.565 0.435
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.565 0.435
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.565 0.435
D53.8 Other specified nutritional anaemias
0.000 0.571 0.429
D53.2 Scorbutic anaemia
0.000 0.571 0.429
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.571 0.429
D53.0 Protein deficiency anaemia
0.000 0.571 0.429
E03.9 Hypothyroidism, unspecified
0.000 0.575 0.425
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.575 0.425
C83.0 Small cell (diffuse)
0.421 0.579 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.579 0.421
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.580 0.420
E21.3 Hyperparathyroidism, unspecified
0.000 0.580 0.420
C95.9 Leukaemia, unspecified
0.418 0.582 0.000
M06.9 Rheumatoid arthritis, unspecified
0.416 0.584 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.590 0.410
E45 Retarded development following protein-energy malnutrition
0.000 0.590 0.410
E43 Unspecified severe protein-energy malnutrition
0.000 0.590 0.410
E42 Marasmic kwashiorkor
0.000 0.590 0.410
E41 Nutritional marasmus
0.000 0.590 0.410
E40 Kwashiorkor
0.000 0.590 0.410
D53.9 Nutritional anaemia, unspecified
0.000 0.592 0.408
M06 Other rheumatoid arthritis
0.407 0.593 0.000
M06.0 Seronegative rheumatoid arthritis
0.405 0.595 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.401 0.599 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.400 0.600 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.399 0.601 0.000
E34.5 Androgen resistance syndrome
0.000 0.601 0.399
E34.4 Constitutional tall stature
0.000 0.601 0.399
E34.3 Short stature, not elsewhere classified
0.000 0.601 0.399
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.601 0.399
E34.1 Other hypersecretion of intestinal hormones
0.000 0.601 0.399
C92 Myeloid leukaemia
0.396 0.603 0.000
D57 Sickle-cell disorders
0.000 0.603 0.396
D55 Anaemia due to enzyme disorders
0.000 0.603 0.396
E28 Ovarian dysfunction
0.000 0.611 0.389
E53 Deficiency of other B group vitamins
0.000 0.611 0.389
D59.1 Other autoimmune haemolytic anaemias
0.000 0.615 0.385
C90.2 Plasmacytoma, extramedullary
0.384 0.616 0.000
D83.8 Other common variable immunodeficiencies
0.000 0.617 0.383
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.617 0.383
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.617 0.383
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.617 0.383
E66 Obesity
0.000 0.623 0.377
C91.5 Adult T-cell leukaemia
0.376 0.623 0.001
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.625 0.375
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.625 0.375
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.625 0.375
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.625 0.375
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.625 0.375
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.625 0.375
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.625 0.375
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.625 0.375
E67 Other hyperalimentation
0.000 0.625 0.375
E68 Sequelae of hyperalimentation
0.000 0.625 0.375
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.375 0.625 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.626 0.374
E00 Congenital iodine-deficiency syndrome
0.000 0.626 0.374
C88.0 Waldenstrom's macroglobulinaemia
0.367 0.633 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.636 0.363
E29.8 Other testicular dysfunction
0.000 0.636 0.363
E29.0 Testicular hyperfunction
0.000 0.636 0.363
E26 Hyperaldosteronism
0.002 0.641 0.357
J45 Asthma
0.000 0.644 0.356
E06 Thyroiditis
0.000 0.644 0.356
D84.8 Other specified immunodeficiencies
0.001 0.646 0.354
D84.1 Defects in the complement system
0.001 0.646 0.354
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.001 0.646 0.354
E34.8 Other specified endocrine disorders
0.000 0.646 0.354
E27.9 Disorder of adrenal gland, unspecified
0.001 0.646 0.353
C91.9 Lymphoid leukaemia, unspecified
0.352 0.647 0.001
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.652 0.348
M06.98 Rheumatoid arthritis, unspecified (Other)
0.346 0.654 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.655 0.345
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.344 0.656 0.000
C81.9 Hodgkin's disease, unspecified
0.341 0.658 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.658 0.341
Chapter II Neoplasms
0.339 0.661 0.000
D56 Thalassaemia
0.000 0.661 0.338
E53.8 Deficiency of other specified B group vitamins
0.000 0.664 0.336
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.336 0.664 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.666 0.333
E63 Other nutritional deficiencies
0.000 0.666 0.333
E56 Other vitamin deficiencies
0.000 0.666 0.333
E50 Vitamin A deficiency
0.000 0.666 0.333
E60 Dietary zinc deficiency
0.000 0.666 0.333
E59 Dietary selenium deficiency
0.000 0.666 0.333
E54 Ascorbic acid deficiency
0.000 0.666 0.333
E52 Niacin deficiency [pellagra]
0.000 0.666 0.333
C73 Malignant neoplasm of thyroid gland
0.333 0.667 0.000
E03.5 Myxoedema coma
0.000 0.667 0.332
E03.4 Atrophy of thyroid (acquired)
0.000 0.667 0.332
E03.3 Postinfectious hypothyroidism
0.000 0.667 0.332
E03.1 Congenital hypothyroidism without goitre
0.000 0.667 0.332
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.667 0.332
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.329 0.670 0.000
D59.8 Other acquired haemolytic anaemias
0.000 0.674 0.326
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.674 0.326
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.674 0.326
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.674 0.326
D59.3 Haemolytic-uraemic syndrome
0.000 0.674 0.326
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.674 0.326
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.674 0.326
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.325 0.675 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.675 0.325
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.676 0.323
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.677 0.323
D58 Other hereditary haemolytic anaemias
0.000 0.678 0.322
C91.8 Mature B-cell leukaemia Burkitt-type
0.315 0.684 0.001
C91.7 Other lymphoid leukaemia
0.315 0.684 0.001
C91.6 Prolymphocytic leukaemia of T-cell type
0.315 0.684 0.001
C91.3 Prolymphocytic leukaemia
0.315 0.684 0.001
C91.2 Subacute lymphocytic leukaemia
0.315 0.684 0.001
E05.8 Other thyrotoxicosis
0.000 0.684 0.316
E05.5 Thyroid crisis or storm
0.000 0.684 0.316
E05.4 Thyrotoxicosis factitia
0.000 0.684 0.316
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.684 0.316
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.684 0.316
E03.8 Other specified hypothyroidism
0.000 0.689 0.311
E51 Thiamine deficiency
0.000 0.691 0.309
E58 Dietary calcium deficiency
0.000 0.693 0.307
D83.9 Common variable immunodeficiency, unspecified
0.001 0.693 0.306
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.305 0.695 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.305 0.695 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.695 0.305
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.695 0.305
D89.3 Immune reconstitution syndrome
0.000 0.695 0.305
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.695 0.305
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.703 0.297
E66.8 Other obesity
0.000 0.704 0.296
E44.1 Mild protein-energy malnutrition
0.000 0.706 0.294
E44.0 Moderate protein-energy malnutrition
0.000 0.706 0.294
M06.8 Other specified rheumatoid arthritis
0.292 0.708 0.000
M06.2 Rheumatoid bursitis
0.292 0.708 0.000
M06.1 Adult-onset Still's disease
0.292 0.708 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.290 0.710 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.290 0.710 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.290 0.710 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.290 0.710 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.290 0.710 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.290 0.710 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.290 0.710 0.000
C43 Malignant melanoma of skin
0.290 0.710 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.711 0.289
C92.9 Myeloid leukaemia, unspecified
0.284 0.715 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.284 0.715 0.000
C92.7 Other myeloid leukaemia
0.284 0.715 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.284 0.715 0.000
C92.5 Acute myelomonocytic leukaemia
0.284 0.715 0.000
C92.4 Acute promyelocytic leukaemia
0.284 0.715 0.000
C92.3 Myeloid sarcoma
0.284 0.715 0.000
C92.2 Subacute myeloid leukaemia
0.284 0.715 0.000
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.715 0.284
D55.8 Other anaemias due to enzyme disorders
0.000 0.715 0.284
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.715 0.284
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.715 0.284
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.715 0.284
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.715 0.284
D57.8 Other sickle-cell disorders
0.000 0.715 0.284
D57.3 Sickle-cell trait
0.000 0.715 0.284
D57.2 Double heterozygous sickling disorders
0.000 0.715 0.284
D57.1 Sickle-cell anaemia without crisis
0.000 0.715 0.284
D57.0 Sickle-cell anaemia with crisis
0.000 0.715 0.284
M45.X9 Ankylosing spondylitis (Site unspecified)
0.283 0.717 0.000
E34.9 Endocrine disorder, unspecified
0.001 0.718 0.281
E11 Non-insulin-dependent diabetes mellitus
0.000 0.720 0.280
E28.9 Ovarian dysfunction, unspecified
0.000 0.721 0.279
E28.8 Other ovarian dysfunction
0.000 0.721 0.279
E28.1 Androgen excess
0.000 0.721 0.279
E28.0 Oestrogen excess
0.000 0.721 0.279
M06.3 Rheumatoid nodule
0.279 0.721 0.000
E53.1 Pyridoxine deficiency
0.000 0.721 0.279
E53.0 Riboflavin deficiency
0.000 0.721 0.279
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.279 0.721 0.000
M06.4 Inflammatory polyarthropathy
0.277 0.723 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.725 0.274
E23 Hypofunction and other disorders of pituitary gland
0.001 0.729 0.270
E66.1 Drug-induced obesity
0.000 0.729 0.270
E67.8 Other specified hyperalimentation
0.000 0.731 0.269
E67.3 Hypervitaminosis D
0.000 0.731 0.269
E67.2 Megavitamin-B6 syndrome
0.000 0.731 0.269
E67.1 Hypercarotenaemia
0.000 0.731 0.269
E67.0 Hypervitaminosis A
0.000 0.731 0.269
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.732 0.268
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.732 0.268
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.732 0.268
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.732 0.268
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.732 0.268
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.732 0.268
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.732 0.268
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.732 0.268
D89.1 Cryoglobulinaemia
0.001 0.734 0.266

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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