TreeWAS – Variant ID: rs4078023

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.174	0.826
R91 Abnormal findings on diagnostic imaging of lung	0.174	0.826
R93 Abnormal findings on diagnostic imaging of other body structures	0.172	0.828
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.166	0.834
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.144	0.856
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.138	0.862
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.135	0.865
R90 Abnormal findings on diagnostic imaging of central nervous system	0.134	0.866
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.134	0.866
R94 Abnormal results of function studies	0.131	0.869
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.131	0.869
R92 Abnormal findings on diagnostic imaging of breast	0.131	0.869
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.129	0.871
R07 Pain in throat and chest	0.128	0.872
R93.6 Abnormal findings on diagnostic imaging of limbs	0.126	0.874
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.126	0.874
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.122	0.878
R00 Abnormalities of heart beat	0.122	0.878
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.120	0.880
R07.3 Other chest pain	0.119	0.881
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.119	0.881
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.118	0.882
R07.2 Precordial pain	0.115	0.884
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.112	0.888
E10-E14 Diabetes mellitus	0.109	0.891
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.108	0.892
R09.1 Pleurisy	0.107	0.893
R00.1 Bradycardia, unspecified	0.106	0.894
E14 Unspecified diabetes mellitus	0.106	0.894
E11 Non-insulin-dependent diabetes mellitus	0.106	0.894
E10 Insulin-dependent diabetes mellitus	0.105	0.895
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.105	0.895
E14.9 Without complications	0.104	0.896
R21 Rash and other nonspecific skin eruption	0.103	0.897
R02 Gangrene, not elsewhere classified	0.102	0.898
R94.5 Abnormal results of liver function studies	0.101	0.899
R07.1 Chest pain on breathing	0.100	0.899
R00.0 Tachycardia, unspecified	0.100	0.900
E10.9 Without complications	0.100	0.900
R03 Abnormal blood-pressure reading, without diagnosis	0.098	0.902
R47-R49 Symptoms and signs involving speech and voice	0.098	0.902
R90.0 Intracranial space-occupying lesion	0.098	0.902
R94.6 Abnormal results of thyroid function studies	0.097	0.902
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.098	0.902
R95-R99 Ill-defined and unknown causes of mortality	0.097	0.903
E11.3 With ophthalmic complications	0.097	0.903
R50-R69 General symptoms and signs	0.096	0.904
R94.4 Abnormal results of kidney function studies	0.096	0.904
R94.0 Abnormal results of function studies of central nervous system	0.096	0.904
R00.8 Other and unspecified abnormalities of heart beat	0.096	0.904
R07.0 Pain in throat	0.095	0.904
R94.3 Abnormal results of cardiovascular function studies	0.095	0.905
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.095	0.905
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.095	0.905
R09.3 Abnormal sputum	0.095	0.905
R22.3 Localised swelling, mass and lump, upper limb	0.093	0.907
E11.4 With neurological complications	0.093	0.907
R09.0 Asphyxia	0.093	0.907
R09.2 Respiratory arrest	0.093	0.907
R94.8 Abnormal results of function studies of other organs and systems	0.093	0.907
R94.2 Abnormal results of pulmonary function studies	0.093	0.907
R26 Abnormalities of gait and mobility	0.092	0.908
R22.0 Localised swelling, mass and lump, head	0.091	0.908
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.090	0.909
R22.2 Localised swelling, mass and lump, trunk	0.090	0.910
R59 Enlarged lymph nodes	0.090	0.910
R05 Cough	0.089	0.911
R01 Cardiac murmurs and other cardiac sounds	0.089	0.911
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.089	0.911
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.089	0.911
R94.7 Abnormal results of other endocrine function studies	0.088	0.911
E11.5 With peripheral circulatory complications	0.088	0.912
R51 Headache	0.086	0.914
E10.4 With neurological complications	0.086	0.914
R04 Haemorrhage from respiratory passages	0.084	0.916
R00.2 Palpitations	0.084	0.916
R03.1 Nonspecific low blood-pressure reading	0.084	0.916
R41 Other symptoms and signs involving cognitive functions and awareness	0.084	0.916
E14.3 With ophthalmic complications	0.084	0.916
E11.1 With ketoacidosis	0.083	0.917
E13 Other specified diabetes mellitus	0.082	0.918
R25 Abnormal involuntary movements	0.082	0.918
R59.0 Localised enlarged lymph nodes	0.081	0.919
R23 Other skin changes	0.081	0.919
R26.8 Other and unspecified abnormalities of gait and mobility	0.081	0.919
R22.1 Localised swelling, mass and lump, neck	0.080	0.919
E11.8 With unspecified complications	0.080	0.920
R22.7 Localised swelling, mass and lump, multiple sites	0.079	0.921
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.079	0.921
E12 Malnutrition-related diabetes mellitus	0.078	0.921
E10.8 With unspecified complications	0.078	0.922
E14.4 With neurological complications	0.078	0.922
E10.2 With renal complications	0.078	0.922
E14.6 With other specified complications	0.078	0.922
R41.0 Disorientation, unspecified	0.078	0.922
E14.5 With peripheral circulatory complications	0.077	0.922
E14.2 Withrenal complications	0.077	0.922
E11.2 With renal complications	0.077	0.923
R73 Elevated blood glucose level	0.077	0.923
R57 Shock, not elsewhere classified	0.077	0.923
E11.7 With multiple complications	0.076	0.923
E10.7 With multiple complications	0.076	0.923
E14.7 With multiple complications	0.076	0.924
E10.1 With ketoacidosis	0.076	0.924
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.076	0.924
E10.5 With peripheral circulatory complications	0.076	0.924
E11.6 With other specified complications	0.076	0.924
E10.3 With ophthalmic complications	0.076	0.924
E10.0 With coma	0.075	0.925
E10.6 With other specified complications	0.075	0.925
R44 Other symptoms and signs involving general sensations and perceptions	0.075	0.925
E14.1 With ketoacidosis	0.075	0.925
R58 Haemorrhage, not elsewhere classified	0.075	0.925
E11.0 With coma	0.074	0.925
E14.0 With coma	0.074	0.926
R46 Symptoms and signs involving appearance and behaviour	0.073	0.927
R27 Other lack of coordination	0.073	0.927
R64 Cachexia	0.072	0.928
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.072	0.928
E14.8 With unspecified complications	0.071	0.928
R52 Pain, not elsewhere classified	0.071	0.928
R50 Fever of unknown origin	0.071	0.928
R49 Voice disturbances	0.071	0.929
R20 Disturbances of skin sensation	0.071	0.929
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.071	0.929
R76 Other abnormal immunological findings in serum	0.071	0.929
R59.1 Generalised enlarged lymph nodes	0.071	0.929
R99 Other ill-defined and unspecified causes of mortality	0.070	0.929
R59.9 Enlarged lymph nodes, unspecified	0.070	0.929
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.070	0.930
R47 Speech disturbances, not elsewhere classified	0.070	0.930
R78 Findings of drugs and other substances, not normally found in blood	0.070	0.930
R96 Other sudden death, cause unknown	0.070	0.930
R95 Sudden infant death syndrome	0.070	0.930
R98 Unattended death	0.070	0.930
R62 Lack of expected normal physiological development	0.070	0.930
R71 Abnormality of red blood cells	0.069	0.931
R40 Somnolence, stupor and coma	0.069	0.931
R22.4 Localised swelling, mass and lump, lower limb	0.069	0.931
R54 Senility	0.068	0.932
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.068	0.932
R77 Other abnormalities of plasma proteins	0.068	0.932
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.068	0.932
R84 Abnormal findings in specimens from respiratory organs and thorax	0.067	0.933
R72 Abnormality of white blood cells, not elsewhere classified	0.067	0.933
R26.2 Difficulty in walking, not elsewhere classified	0.067	0.933
R74 Abnormal serum enzyme levels	0.067	0.933
R26.1 Paralytic gait	0.066	0.934
R83 Abnormal findings in cerebrospinal fluid	0.066	0.934
R60 Oedema, not elsewhere classified	0.066	0.934
R29.2 Abnormal reflex	0.065	0.935
R29.1 Meningismus	0.065	0.935
Chapter IV Endocrine, nutritional and metabolic diseases	0.065	0.935
R01.0 Benign and innocent cardiac murmurs	0.065	0.935
R68 Other general symptoms and signs	0.065	0.935
R73.0 Abnormal glucose tolerance test	0.065	0.935
R89 Abnormal findings in specimens from other organs, systems and tissues	0.064	0.935
R01.2 Other cardiac sounds	0.064	0.936
R26.0 Ataxic gait	0.064	0.936
R29.4 Clicking hip	0.064	0.936
R29.3 Abnormal posture	0.064	0.936
R43 Disturbances of smell and taste	0.064	0.936
E13.9 Without complications	0.064	0.936
R26.3 Immobility	0.063	0.937
R25.2 Cramp and spasm	0.063	0.937
R41.2 Retrograde amnesia	0.063	0.937
R04.8 Haemorrhage from other sites in respiratory passages	0.063	0.937
R44.3 Hallucinations, unspecified	0.062	0.937
R04.2 Haemoptysis	0.062	0.938
R61 Hyperhidrosis	0.062	0.938
R29.0 Tetany	0.062	0.938
R23.3 Spontaneous ecchymoses	0.062	0.938
R25.8 Other and unspecified abnormal involuntary movements	0.061	0.939
R04.1 Haemorrhage from throat	0.061	0.939
R86 Abnormal findings in specimens from male genital organs	0.061	0.939
R45 Symptoms and signs involving emotional state	0.061	0.939
R04.9 Haemorrhage from respiratory passages, unspecified	0.061	0.939
R23.1 Pallor	0.060	0.939
R23.0 Cyanosis	0.060	0.940
R41.1 Anterograde amnesia	0.060	0.940
R57.2 Septic shock	0.060	0.940
# Top node	0.059	0.941
E13.8 With unspecified complications	0.059	0.941
E13.7 With multiple complications	0.059	0.941
E13.6 With other specified complications	0.059	0.941
E13.5 With peripheral circulatory complications	0.059	0.941
E13.4 With neurological complications	0.059	0.941
E13.2 With renal complications	0.059	0.941
E13.1 With ketoacidosis	0.059	0.941
E13.0 With coma	0.059	0.941
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.059	0.941
R25.0 Abnormal head movements	0.059	0.941
I25 Chronic ischaemic heart disease	0.059	0.941
E50-E64 Other nutritional deficiencies	0.059	0.941
I25.2 Old myocardial infarction	0.059	0.941
R25.3 Fasciculation	0.058	0.941
R44.1 Visual hallucinations	0.058	0.942
R56 Convulsions, not elsewhere classified	0.058	0.942
R22.9 Localised swelling, mass and lump, unspecified	0.057	0.942
R23.2 Flushing	0.057	0.942
R50.9 Fever, unspecified	0.058	0.942
E13.3 With ophthalmic complications	0.057	0.943
R57.0 Cardiogenic shock	0.057	0.943
R01.1 Cardiac murmur, unspecified	0.057	0.943
R87 Abnormal findings in specimens from female genital organs	0.056	0.943
I20-I25 Ischaemic heart diseases	0.057	0.943
E12.9 Without complications	0.056	0.943
E12.8 With unspecified complications	0.056	0.943
E12.7 With multiple complications	0.056	0.943
E12.6 With other specified complications	0.056	0.943
E12.5 With peripheral circulatory complications	0.056	0.943
E12.4 With neurological complications	0.056	0.943
E12.3 With ophthalmic complications	0.056	0.943
E12.2 With renal complications	0.056	0.943
E12.1 With ketoacidosis	0.056	0.943
E12.0 With coma	0.056	0.943
R47.0 Dysphasia and aphasia	0.056	0.943
R52.9 Pain, unspecified	0.056	0.944
R57.9 Shock, unspecified	0.056	0.944
R57.1 Hypovolaemic shock	0.056	0.944
R81 Glycosuria	0.055	0.944
R57.8 Other shock	0.055	0.945
R42 Dizziness and giddiness	0.055	0.945
R69 Unknown and unspecified causes of morbidity	0.055	0.945
R44.2 Other hallucinations	0.055	0.945
R46.2 Strange and inexplicable behaviour	0.055	0.945
R23.8 Other and unspecified skin changes	0.054	0.945
R76.8 Other specified abnormal immunological findings in serum	0.054	0.946
R73.9 Hyperglycaemia, unspecified	0.054	0.946
R82 Other abnormal findings in urine	0.054	0.946
R52.2 Other chronic pain	0.054	0.946
R46.8 Other symptoms and signs involving appearance and behaviour	0.054	0.946
Chapter VII Diseases of the eye and adnexa	0.054	0.946
R55 Syncope and collapse	0.054	0.946
R46.0 Very low level of personal hygiene	0.053	0.946
I25.9 Chronic ischaemic heart disease, unspecified	0.054	0.946
R40.0 Somnolence	0.053	0.947
R25.1 Tremor, unspecified	0.053	0.947
R65.1 Systemic Inflammatory Response Syndrome of infectious origin with organ failure	0.053	0.947
Chapter IX Diseases of the circulatory system	0.053	0.947
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.053	0.947
R46.6 Undue concern and preoccupation with stressful events	0.053	0.947
R46.5 Suspiciousness and marked evasiveness	0.053	0.947
R46.3 Overactivity	0.053	0.947
R46.1 Bizarre personal appearance	0.053	0.947
R76.0 Raised antibody titer	0.052	0.947
R20.1 Hypoaesthesia of skin	0.052	0.948
R49.1 Aphonia	0.052	0.948
R20.3 Hyperaesthesia	0.052	0.948
R50.2 Drug-induced fever	0.052	0.948
R70.0 Elevated erythrocyte sedimentation rate	0.052	0.948
R49.0 Dysphonia	0.052	0.948
I70-I79 Diseases of arteries, arterioles and capillaries	0.052	0.948
R65.9 Systemic Inflammatory Response Syndrome, unspecified	0.052	0.948
R46.4 Slowness and poor responsiveness	0.052	0.948
R65.0 Systemic Inflammatory Response Syndrome of infectious origin without organ failure	0.052	0.948
R78.0 Finding of alcohol in blood	0.052	0.948
R48.0 Dyslexia and alexia	0.052	0.948
R48.8 Other and unspecified symbolic dysfunctions	0.051	0.948
R65.3 Systemic Inflammatory Response Syndrome of non-infectious origin with organ failure	0.051	0.948
R65.2 Systemic Inflammatory Response Syndrome of non-infectious origin without organ failure	0.051	0.948
R29.6 Tendency to fall, not elsewhere classified	0.051	0.948
R78.8 Finding of other specified substances, not normally found in blood	0.051	0.948
R49.2 Hypernasality and hyponasality	0.051	0.948
E53 Deficiency of other B group vitamins	0.051	0.948
R27.8 Other and unspecified lack of coordination	0.051	0.949
R48.2 Apraxia	0.051	0.949
R48.1 Agnosia	0.051	0.949
R70.1 Abnormal plasma viscosity	0.051	0.949
R76.2 False-positive serological test for syphilis	0.051	0.949
R76.1 Abnormal reaction to tuberculin test	0.051	0.949
R52.0 Acute pain	0.051	0.949
R85.7 Abnormal histological findings	0.051	0.949
R49.8 Other and unspecified voice disturbances	0.050	0.949
R78.9 Finding of unspecified substance, not normally found in blood	0.050	0.949
R78.7 Finding of abnormal level of heavy metals in blood	0.050	0.949
R78.6 Finding of steroid agent in blood	0.050	0.949
R78.5 Finding of psychotropic drug in blood	0.050	0.949
R78.4 Finding of other drugs of addictive potential in blood	0.050	0.949
R78.3 Finding of hallucinogen in blood	0.050	0.949
R78.2 Finding of cocaine in blood	0.050	0.949
R78.1 Finding of opiate drug in blood	0.050	0.949
R50.1 Persistent fever	0.050	0.949
R62.8 Other lack of expected normal physiological development	0.050	0.949
R95.9 Sudden infant death syndrome without mention of autopsy	0.050	0.950
R95.0 Sudden infant death syndrome with mention of autopsy	0.050	0.950
R96.1 Death occurring less than 24 hours from onset of symptoms, not otherwise explained	0.050	0.950
R96.0 Instantaneous death	0.050	0.950
Chapter XII Diseases of the skin and subcutaneous tissue	0.050	0.950
I73 Other peripheral vascular diseases	0.050	0.950
R62.9 Lack of expected normal physiological development, unspecified	0.050	0.950
R62.0 Delayed milestone	0.050	0.950
R85.5 Abnormal microbiological findings	0.050	0.950
R50.8 Other specified fever	0.050	0.950
R77.1 Abnormality of globulin	0.050	0.950
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.050	0.950
I20 Angina pectoris	0.050	0.950
R47.1 Dysarthria and anarthria	0.050	0.950
R76.9 Abnormal immunological finding in serum, unspecified	0.049	0.950
R85.8 Other abnormal findings	0.049	0.950
R84.5 Abnormal microbiological findings	0.049	0.950
R40.2 Coma, unspecified	0.049	0.950
R77.0 Abnormality of albumin	0.049	0.951
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.049	0.951
R41.3 Other amnesia	0.049	0.951
R85.9 Unspecified abnormal finding	0.049	0.951
R20.8 Other and unspecified disturbances of skin sensation	0.049	0.951
E11.9 Without complications	0.049	0.951
R84.6 Abnormal cytological findings	0.049	0.951
R84.7 Abnormal histological findings	0.049	0.951
R77.2 Abnormality of alphafetoprotein	0.049	0.951
R85.4 Abnormal immunological findings	0.049	0.951
R85.3 Abnormal level of substances chiefly nonmedicinal as to source	0.049	0.951
R85.2 Abnormal level of other drugs, medicaments and biological substances	0.049	0.951
R85.1 Abnormal level of hormones	0.049	0.951
R85.0 Abnormal level of enzymes	0.049	0.951
R74.9 Abnormal level of unspecified serum enzyme	0.049	0.951
R84.9 Unspecified abnormal finding	0.049	0.951
I73.9 Peripheral vascular disease, unspecified	0.049	0.951
R20.0 Anaesthesia of skin	0.048	0.951
R77.9 Abnormality of plasma protein, unspecified	0.048	0.951
R84.8 Other abnormal findings	0.048	0.951
R84.4 Abnormal immunological findings	0.048	0.951
R84.3 Abnormal level of substances chiefly nonmedicinal as to source	0.048	0.951
R84.2 Abnormal level of other drugs, medicaments and biological substances	0.048	0.951
R84.1 Abnormal level of hormones	0.048	0.951
R84.0 Abnormal level of enzymes	0.048	0.951
R83.8 Other abnormal findings	0.048	0.952
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.048	0.952
R60.1 Generalised oedema	0.048	0.952
R68.0 Hypothermia, not associated with low environmental temperature	0.048	0.952
R83.5 Abnormal microbiological findings	0.048	0.952
R50.0 Fever with chills	0.048	0.952
R77.8 Other specified abnormalities of plasma proteins	0.048	0.952
R68.2 Dry mouth, unspecified	0.048	0.952
R83.9 Unspecified abnormal finding	0.047	0.952
R83.7 Abnormal histological findings	0.047	0.952
R83.6 Abnormal cytological findings	0.047	0.952
R83.4 Abnormal immunological findings	0.047	0.952
R83.3 Abnormal level of substances chiefly nonmedicinal as to source	0.047	0.952
R83.2 Abnormal level of other drugs, medicaments and biological substances	0.047	0.952
R83.1 Abnormal level of hormones	0.047	0.952
R83.0 Abnormal level of enzymes	0.047	0.952
Chapter V Mental and behavioural disorders	0.048	0.952
R44.0 Auditory hallucinations	0.047	0.952
R68.3 Clubbing of fingers	0.047	0.952
L00-L08 Infections of the skin and subcutaneous tissue	0.048	0.952
R43.0 Anosmia	0.047	0.953
R89.5 Abnormal microbiological findings	0.047	0.953
R85.6 Abnormal cytological findings	0.047	0.953
R06 Abnormalities of breathing	0.047	0.953
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.047	0.953
R27.0 Ataxia, unspecified	0.047	0.953
R89.0 Abnormal level of enzymes	0.047	0.953
R89.4 Abnormal immunological findings	0.047	0.953
R89.9 Unspecified abnormal finding	0.047	0.953
R89.6 Abnormal cytological findings	0.047	0.953
R68.1 Nonspecific symptoms peculiar to infancy	0.047	0.953
R23.4 Changes in skin texture	0.046	0.953
H30-H36 Disorders of choroid and retina	0.047	0.953
Chapter XV Pregnancy, childbirth and the puerperium	0.047	0.953
R89.3 Abnormal level of substances chiefly nonmedicinal as to source	0.046	0.953
R89.2 Abnormal level of other drugs, medicaments and biological substances	0.046	0.953
R89.1 Abnormal level of hormones	0.046	0.953
I25.5 Ischaemic cardiomyopathy	0.046	0.953
H43-H45 Disorders of vitreous body and globe	0.046	0.953
R61.0 Localised hyperhidrosis	0.046	0.954
R60.9 Oedema, unspecified	0.046	0.954
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.046	0.954
I22 Subsequent myocardial infarction	0.046	0.954
E55 Vitamin D deficiency	0.046	0.954
E61 Deficiency of other nutrient elements	0.046	0.954
I25.1 Atherosclerotic heart disease	0.046	0.954
I74 Arterial embolism and thrombosis	0.046	0.954
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.046	0.954
E53.8 Deficiency of other specified B group vitamins	0.046	0.954
R89.7 Abnormal histological findings	0.045	0.954
R52.1 Chronic intractable pain	0.045	0.955
R89.8 Other abnormal findings	0.045	0.955
R86.9 Unspecified abnormal finding	0.045	0.955
R43.1 Parosmia	0.045	0.955
R40.1 Stupor	0.045	0.955
R43.2 Parageusia	0.044	0.955
R86.6 Abnormal cytological findings	0.044	0.955
E40-E46 Malnutrition	0.044	0.955
R86.0 Abnormal level of enzymes	0.044	0.955
I25.4 Coronary artery aneurysm	0.044	0.955
I77 Other disorders of arteries and arterioles	0.044	0.956
R60.0 Localised oedema	0.044	0.956
R45.7 State of emotional shock and stress, unspecified	0.044	0.956
R86.1 Abnormal level of hormones	0.044	0.956
R74.8 Abnormal levels of other serum enzymes	0.044	0.956
R86.4 Abnormal immunological findings	0.044	0.956
R86.3 Abnormal level of substances chiefly nonmedicinal as to source	0.044	0.956
R86.2 Abnormal level of other drugs, medicaments and biological substances	0.044	0.956
R45.3 Demoralisation and apathy	0.044	0.956
R45.0 Nervousness	0.043	0.956
O60-O75 Complications of labour and delivery	0.043	0.957
R61.1 Generalised hyperhidrosis	0.043	0.957
L03 Cellulitis	0.043	0.957
R47.8 Other and unspecified speech disturbances	0.043	0.957
R45.4 Irritability and anger	0.043	0.957
F30-F39 Mood [affective] disorders	0.043	0.957
E58 Dietary calcium deficiency	0.043	0.957
E51 Thiamine deficiency	0.043	0.957
R86.7 Abnormal histological findings	0.043	0.957
I25.0 Atherosclerotic cardiovascular disease, so described	0.043	0.957
R45.6 Physical violence	0.043	0.957
E56 Other vitamin deficiencies	0.043	0.957
R87.7 Abnormal histological findings	0.043	0.957
Chapter XVI Certain conditions originating in the perinatal period	0.043	0.957
R45.5 Hostility	0.042	0.957
E63 Other nutritional deficiencies	0.043	0.957
F10 Mental and behavioural disorders due to use of alcohol	0.043	0.957
R86.8 Other abnormal findings	0.042	0.957
R45.2 Unhappiness	0.042	0.957
R53 Malaise and fatigue	0.042	0.957
E64 Sequelae of malnutrition and other nutritional deficiencies	0.042	0.957
E50 Vitamin A deficiency	0.042	0.957
E60 Dietary zinc deficiency	0.042	0.957
E59 Dietary selenium deficiency	0.042	0.957
E52 Niacin deficiency [pellagra]	0.042	0.957
Chapter VI Diseases of the nervous system	0.042	0.958
R87.9 Unspecified abnormal finding	0.042	0.958
R07.4 Chest pain, unspecified	0.042	0.958
Chapter XIV Diseases of the genitourinary system	0.042	0.958
R43.8 Other and unspecified disturbances of smell and taste	0.042	0.958
Chapter XXII Codes for special purposes	0.042	0.958
R56.0 Febrile convulsions	0.042	0.958
H36 Retinal disorders in diseases classified elsewhere	0.042	0.958
R45.8 Other symptoms and signs involving emotional state	0.042	0.958
R04.0 Epistaxis	0.042	0.958
I23 Certain current complications following acute myocardial infarction	0.042	0.958
R79 Other abnormal findings of blood chemistry	0.042	0.958
R45.1 Restlessness and agitation	0.041	0.959
R87.0 Abnormal level of enzymes	0.041	0.959
R87.5 Abnormal microbiological findings	0.041	0.959
I25.6 Silent myocardial ischaemia	0.041	0.959
E54 Ascorbic acid deficiency	0.041	0.959
R87.8 Other abnormal findings	0.041	0.959
R87.4 Abnormal immunological findings	0.041	0.959
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.041	0.959
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.041	0.959
R87.1 Abnormal level of hormones	0.041	0.959
R86.5 Abnormal microbiological findings	0.040	0.959
R20.2 Paraesthesia of skin	0.041	0.959
I20.9 Angina pectoris, unspecified	0.041	0.959
L03.1 Cellulitis of other parts of limb	0.041	0.959
H55-H59 Other disorders of eye and adnexa	0.040	0.959
I20.0 Unstable angina	0.040	0.960
F10.2 Dependence syndrome	0.040	0.960
H01 Other inflammation of eyelid	0.040	0.960
H46-H48 Disorders of optic nerve and visual pathways	0.040	0.960
I25.3 Aneurysm of heart	0.040	0.960
O68 Labour and delivery complicated by foetal stress [distress]	0.040	0.960
N40-N51 Diseases of male genital organs	0.040	0.960
F32 Depressive episode	0.040	0.960
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.040	0.960
Z72.0 Tobacco use	0.040	0.960
L40-L45 Papulosquamous disorders	0.040	0.960
R82.4 Acetonuria	0.039	0.960
E65-E68 Obesity and other hyperalimentation	0.039	0.960
H10-H13 Disorders of conjunctiva	0.039	0.961
H43 Disorders of vitreous body	0.039	0.961
R82.1 Myoglobinuria	0.039	0.961
R82.7 Abnormal findings on microbiological examination of urine	0.039	0.961
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.039	0.961
L20-L30 Dermatitis and eczema	0.039	0.961
L08 Other local infections of skin and subcutaneous tissue	0.039	0.961
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.039	0.961
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.039	0.961
R82.3 Haemoglobinuria	0.039	0.961
R82.2 Biliuria	0.039	0.961
R82.0 Chyluria	0.039	0.961
I24 Other acute ischaemic heart diseases	0.039	0.961
H36.0 Diabetic retinopathy	0.039	0.961
Chapter XX External causes of morbidity and mortality	0.039	0.961
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.039	0.961
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.039	0.961
N70-N77 Inflammatory diseases of female pelvic organs	0.039	0.961
I00-I02 Acute rheumatic fever	0.038	0.961
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.039	0.961
R63 Symptoms and signs concerning food and fluid intake	0.038	0.962
F17 Mental and behavioural disorders due to use of tobacco	0.038	0.962
R68.8 Other specified general symptoms and signs	0.038	0.962
E53.9 Vitamin B deficiency, unspecified	0.038	0.962
H25-H28 Disorders of lens	0.038	0.962
I73.8 Other specified peripheral vascular diseases	0.038	0.962
N41 Inflammatory diseases of prostate	0.038	0.962
R61.9 Hyperhidrosis, unspecified	0.037	0.962
I20.8 Other forms of angina pectoris	0.037	0.962
I70 Atherosclerosis	0.037	0.963
L05 Pilonidal cyst	0.037	0.963
R82.8 Abnormal findings on cytological and histological examination of urine	0.037	0.963
R82.9 Other and unspecified abnormal finding in urine	0.037	0.963
E53.1 Pyridoxine deficiency	0.037	0.963
E53.0 Riboflavin deficiency	0.037	0.963
H04 Disorders of lachrymal system	0.037	0.963
E55.9 Vitamin D deficiency, unspecified	0.037	0.963
I05-I09 Chronic rheumatic heart diseases	0.037	0.963

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations