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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4134947
log Bayes Factor = 11.4935
Chromosome 6   position 20,483,770  (GRCh37) Explore rs4134947 on Ensembl!
Variant rs4134947 is part of Cluster X0041

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
M75 Shoulder lesions
0.999 0.001 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
H43-H45 Disorders of vitreous body and globe
0.996 0.004 0.000
H43 Disorders of vitreous body
0.993 0.007 0.000
M75.4 Impingement syndrome of shoulder
0.988 0.012 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.984 0.016 0.000
H43.1 Vitreous haemorrhage
0.981 0.019 0.000
Chapter V Mental and behavioural disorders
0.980 0.020 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.971 0.029 0.000
M23 Internal derangement of knee
0.967 0.033 0.000
M25 Other joint disorders, not elsewhere classified
0.964 0.036 0.000
M50-M54 Other dorsopathies
0.962 0.038 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.960 0.040 0.000
S60-S69 Injuries to the wrist and hand
0.960 0.040 0.000
H30-H36 Disorders of choroid and retina
0.960 0.040 0.000
M79.8 Other specified soft tissue disorders
0.954 0.046 0.000
F30-F39 Mood [affective] disorders
0.949 0.051 0.000
Chapter XXI Factors influencing health status and contact with health services
0.948 0.052 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.947 0.053 0.000
H43.8 Other disorders of vitreous body
0.942 0.058 0.000
Chapter IX Diseases of the circulatory system
0.941 0.059 0.000
C15-C26 Malignant neoplasms of digestive organs
0.940 0.060 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.936 0.064 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.934 0.066 0.000
C34 Malignant neoplasm of bronchus and lung
0.933 0.067 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.931 0.069 0.000
M54 Dorsalgia
0.931 0.069 0.000
S61 Open wound of wrist and hand
0.929 0.071 0.000
F33 Recurrent depressive disorder
0.928 0.072 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.927 0.073 0.000
M23.3 Other meniscus derangements
0.924 0.076 0.000
I30-I52 Other forms of heart disease
0.924 0.076 0.000
C64-C68 Malignant neoplasms of urinary tract
0.922 0.078 0.000
I51 Complications and ill-defined descriptions of heart disease
0.921 0.079 0.000
M75.0 Adhesive capsulitis of shoulder
0.921 0.079 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.919 0.081 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.918 0.082 0.000
Z92 Personal history of medical treatment
0.917 0.083 0.000
H33 Retinal detachments and breaks
0.916 0.084 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.914 0.086 0.000
S00-S09 Injuries to the head
0.906 0.094 0.000
S61.0 Open wound of finger(s) without damage to nail
0.906 0.094 0.000
M31 Other necrotising vasculopathies
0.904 0.096 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.902 0.098 0.000
I51.8 Other ill-defined heart diseases
0.899 0.101 0.000
H33.3 Retinal breaks without detachment
0.895 0.105 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.894 0.106 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.891 0.109 0.000
O60-O75 Complications of labour and delivery
0.885 0.115 0.000
S01 Open wound of head
0.882 0.118 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.882 0.118 0.000
M54.9 Dorsalgia, unspecified
0.880 0.120 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.876 0.124 0.000
I51.7 Cardiomegaly
0.873 0.127 0.000
I60-I69 Cerebrovascular diseases
0.871 0.129 0.000
M75.1 Rotator cuff syndrome
0.871 0.129 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.870 0.130 0.000
H40-H42 Glaucoma
0.869 0.131 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.867 0.133 0.000
C67 Malignant neoplasm of bladder
0.866 0.134 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.864 0.136 0.000
Z85 Personal history of malignant neoplasm
0.859 0.141 0.000
C34.3 Lower lobe, bronchus or lung
0.858 0.142 0.000
M24 Other specific joint derangements
0.856 0.144 0.000
M15-M19 Arthrosis
0.856 0.144 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.856 0.144 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.854 0.146 0.000
S70-S79 Injuries to the hip and thigh
0.852 0.148 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.849 0.151 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.849 0.151 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.849 0.151 0.000
Chapter XX External causes of morbidity and mortality
0.844 0.156 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.843 0.157 0.000
H52 Disorders of refraction and accommodation
0.842 0.158 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.841 0.159 0.000
C16 Malignant neoplasm of stomach
0.839 0.161 0.000
F33.9 Recurrent depressive disorder, unspecified
0.838 0.161 0.000
M75.5 Bursitis of shoulder
0.838 0.162 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.838 0.162 0.000
M31.6 Other giant cell arteritis
0.836 0.164 0.000
M25.8 Other specified joint disorders
0.835 0.165 0.000
M54.4 Lumbago with sciatica
0.833 0.167 0.000
M25.7 Osteophyte
0.830 0.170 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.830 0.170 0.000
M71 Other bursopathies
0.822 0.178 0.000
C21 Malignant neoplasm of anus and anal canal
0.820 0.180 0.000
H35 Other retinal disorders
0.819 0.181 0.000
Z03.1 Observation for suspected malignant neoplasm
0.819 0.181 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.819 0.181 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.816 0.184 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.815 0.185 0.000
M16 Coxarthrosis [arthrosis of hip]
0.815 0.185 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.812 0.188 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.811 0.189 0.000
F99-F99 Unspecified mental disorder
0.809 0.191 0.000
I44 Atrioventricular and left bundle-branch block
0.808 0.192 0.000
I45 Other conduction disorders
0.808 0.192 0.000
C34.2 Middle lobe, bronchus or lung
0.805 0.195 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.804 0.196 0.000
C80 Malignant neoplasm without specification of site
0.801 0.199 0.000
Q60-Q64 Congenital malformations of the urinary system
0.800 0.200 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.798 0.202 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.798 0.202 0.000
C20 Malignant neoplasm of rectum
0.798 0.202 0.000
H31 Other disorders of choroid
0.797 0.203 0.000
M35 Other systemic involvement of connective tissue
0.795 0.205 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.794 0.206 0.000
O36 Maternal care for other known or suspected foetal problems
0.790 0.210 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.788 0.212 0.000
H55-H59 Other disorders of eye and adnexa
0.787 0.212 0.000
Z84 Family history of other conditions
0.787 0.213 0.000
M22 Disorders of patella
0.787 0.213 0.000
S10-S19 Injuries to the neck
0.787 0.213 0.000
M75.3 Calcific tendinitis of shoulder
0.787 0.213 0.000
I61 Intracerebral haemorrhage
0.785 0.215 0.000
O72 Postpartum haemorrhage
0.785 0.215 0.000
F60-F69 Disorders of adult personality and behaviour
0.785 0.215 0.000
I71 Aortic aneurysm and dissection
0.784 0.216 0.000
M25.3 Other instability of joint
0.783 0.217 0.000
Z90.7 Acquired absence of genital organ(s)
0.781 0.219 0.000
Z90.8 Acquired absence of other organs
0.780 0.220 0.000
M60-M63 Disorders of muscles
0.779 0.221 0.000
O63 Long labour
0.779 0.221 0.000
S69 Other and unspecified injuries of wrist and hand
0.777 0.223 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.777 0.223 0.000
M16.1 Other primary coxarthrosis
0.777 0.223 0.000
I34 Nonrheumatic mitral valve disorders
0.776 0.224 0.000
Chapter XXII Codes for special purposes
0.776 0.224 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.775 0.225 0.000
H40 Glaucoma
0.775 0.225 0.000
C79 Secondary malignant neoplasm of other sites
0.774 0.226 0.000
H10-H13 Disorders of conjunctiva
0.774 0.226 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.773 0.227 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.772 0.228 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.772 0.228 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.772 0.228 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.770 0.230 0.000
C77.2 Intra-abdominal lymph nodes
0.770 0.230 0.000
H44 Disorders of globe
0.768 0.232 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.768 0.232 0.000
M76 Enthesopathies of lower limb, excluding foot
0.766 0.234 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.765 0.235 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.764 0.236 0.000
Z90.1 Acquired absence of breast(s)
0.764 0.236 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.764 0.236 0.000
Z13 Special screening examination for other diseases and disorders
0.762 0.238 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.761 0.239 0.000
Q80-Q89 Other congenital malformations
0.760 0.240 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.760 0.240 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.758 0.241 0.000
C77.1 Intrathoracic lymph nodes
0.758 0.242 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.757 0.243 0.000
W00-W19 Falls
0.757 0.243 0.000
M79.6 Pain in limb
0.755 0.245 0.000
M51 Other intervertebral disk disorders
0.754 0.246 0.000
M45-M49 Spondylopathies
0.753 0.247 0.000
M16.0 Primary coxarthrosis, bilateral
0.752 0.248 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.751 0.249 0.000
S90-S99 Injuries to the ankle and foot
0.751 0.249 0.000
C34.1 Upper lobe, bronchus or lung
0.750 0.250 0.000
D00-D09 In situ neoplasms
0.750 0.250 0.000
M79.88 Other specified soft tissue disorders (Other)
0.750 0.250 0.000
D45 Polycythaemia vera
0.749 0.251 0.000
C16.9 Stomach, unspecified
0.748 0.252 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.747 0.253 0.000
O42 Premature rupture of membranes
0.746 0.254 0.000
M65-M68 Disorders of synovium and tendon
0.745 0.255 0.000
M24.1 Other articular cartilage disorders
0.743 0.257 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.742 0.257 0.000
S01.2 Open wound of nose
0.742 0.258 0.000
I60 Subarachnoid haemorrhage
0.742 0.258 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.742 0.258 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.742 0.258 0.000
S62 Fracture at wrist and hand level
0.741 0.259 0.000
C43 Malignant melanoma of skin
0.741 0.259 0.000
O36.5 Maternal care for poor foetal growth
0.740 0.260 0.000
C50-C50 Malignant neoplasm of breast
0.739 0.261 0.000
S01.9 Open wound of head, part unspecified
0.739 0.261 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.738 0.262 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.737 0.263 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.737 0.263 0.000
D47.2 Monoclonal gammopathy
0.736 0.264 0.000
Z85.6 Personal history of leukaemia
0.735 0.265 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.735 0.265 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.734 0.266 0.000
I44.7 Left bundle-branch block, unspecified
0.734 0.266 0.000
S06 Intracranial injury
0.734 0.266 0.000
C34.9 Bronchus or lung, unspecified
0.732 0.268 0.000
S01.1 Open wound of eyelid and periocular area
0.731 0.268 0.000
Z03.4 Observation for suspected myocardial infarction
0.730 0.270 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.730 0.270 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.727 0.273 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.727 0.273 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.726 0.274 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.726 0.274 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.724 0.276 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.724 0.276 0.000
C67.8 Overlapping lesion of bladder
0.723 0.277 0.000
S01.0 Open wound of scalp
0.723 0.277 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.723 0.277 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.722 0.278 0.000
D47.1 Chronic myeloproliferative disease
0.722 0.278 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.722 0.278 0.000
M54.5 Low back pain
0.722 0.278 0.000
C77.4 Inguinal and lower limb lymph nodes
0.722 0.278 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.721 0.279 0.000
H40.9 Glaucoma, unspecified
0.720 0.280 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.720 0.280 0.000
Z00.6 Examination for normal comparison and control in clinical research programme
0.719 0.281 0.000
Z83 Family history of other specific disorders
0.719 0.281 0.000
M86-M90 Other osteopathies
0.718 0.282 0.000
M79.66 Pain in limb (Lower leg)
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
I42 Cardiomyopathy
0.717 0.283 0.000
M75.8 Other shoulder lesions
0.716 0.284 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M34 Systemic sclerosis
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
Chapter VI Diseases of the nervous system
0.716 0.284 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.715 0.285 0.000
H40.0 Glaucoma suspect
0.715 0.285 0.000
M77 Other enthesopathies
0.714 0.286 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.714 0.286 0.000
I45.1 Other and unspecified right bundle-branch block
0.713 0.287 0.000
T36 Poisoning by systemic antibiotics
0.712 0.287 0.000
H52.1 Myopia
0.712 0.288 0.000
H53-H54 Visual disturbances and blindness
0.712 0.288 0.000
H43.9 Disorder of vitreous body, unspecified
0.712 0.288 0.000
H43.2 Crystalline deposits in vitreous body
0.712 0.288 0.000
H43.0 Vitreous prolapse
0.712 0.288 0.000
O72.1 Other immediate postpartum haemorrhage
0.712 0.288 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.712 0.288 0.000
M21 Other acquired deformities of limbs
0.711 0.289 0.000
O48 Prolonged pregnancy
0.711 0.289 0.000
M79.1 Myalgia
0.710 0.290 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.709 0.291 0.000
M25.4 Effusion of joint
0.709 0.291 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.707 0.293 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.706 0.294 0.000
T33-T35 Frostbite
0.706 0.294 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.706 0.294 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.706 0.294 0.000
T00-T07 Injuries involving multiple body regions
0.706 0.294 0.000
M75.9 Shoulder lesion, unspecified
0.705 0.294 0.000
C51-C58 Malignant neoplasms of female genital organs
0.705 0.295 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.705 0.295 0.000
M23.8 Other internal derangements of knee
0.705 0.295 0.000
Z97 Presence of other devices
0.703 0.297 0.000
Z89 Acquired absence of limb
0.703 0.297 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.703 0.297 0.000
F80-F89 Disorders of psychological development
0.703 0.297 0.000
F70-F79 Mental retardation
0.703 0.297 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.703 0.297 0.000
I51.4 Myocarditis, unspecified
0.701 0.299 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.701 0.299 0.000
C67.6 Ureteric orifice
0.699 0.301 0.000
H52.2 Astigmatism
0.699 0.301 0.000
F31 Bipolar affective disorder
0.699 0.301 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.698 0.302 0.000
H50 Other strabismus
0.697 0.303 0.000
O85-O92 Complications predominantly related to the puerperium
0.697 0.303 0.000
M79.5 Residual foreign body in soft tissue
0.696 0.304 0.000
M79.9 Soft tissue disorder, unspecified
0.696 0.304 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.696 0.304 0.000
M79.3 Panniculitis, unspecified
0.696 0.304 0.000
M79.2 Neuralgia and neuritis, unspecified
0.696 0.304 0.000
Z90.5 Acquired absence of kidney
0.696 0.304 0.000
C67.3 Anterior wall of bladder
0.695 0.305 0.000
O41 Other disorders of amniotic fluid and membranes
0.695 0.305 0.000
S70 Superficial injury of hip and thigh
0.695 0.305 0.000
S68 Traumatic amputation of wrist and hand
0.694 0.306 0.000
H43.3 Other vitreous opacities
0.694 0.306 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.694 0.306 0.000
H49 Paralytic strabismus
0.694 0.306 0.000
W20-W49 Exposure to inanimate mechanical forces
0.694 0.306 0.000
M23.9 Internal derangement of knee, unspecified
0.693 0.307 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.693 0.307 0.000
M23.1 Discoid meniscus (congenital)
0.693 0.307 0.000
M23.0 Cystic meniscus
0.693 0.307 0.000
Z84.8 Family history of other specified conditions
0.693 0.307 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.693 0.307 0.000
C67.2 Lateral wall of bladder
0.693 0.307 0.000
H33.5 Other retinal detachments
0.693 0.307 0.000
S64 Injury of nerves at wrist and hand level
0.692 0.308 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.692 0.308 0.000
S01.8 Open wound of other parts of head
0.692 0.308 0.000
M25.9 Joint disorder, unspecified
0.691 0.309 0.000
M25.2 Flail joint
0.691 0.309 0.000
M25.1 Fistula of joint
0.691 0.309 0.000
M25.0 Haemarthrosis
0.691 0.309 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.690 0.310 0.000
H35.6 Retinal haemorrhage
0.689 0.311 0.000
Z92.8 Personal history of other medical treatment
0.689 0.311 0.000
O63.0 Prolonged first stage (of labour)
0.689 0.311 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.689 0.311 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.688 0.312 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.688 0.312 0.000
C31 Malignant neoplasm of accessory sinuses
0.688 0.312 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.688 0.312 0.000
C37 Malignant neoplasm of thymus
0.688 0.312 0.000
C33 Malignant neoplasm of trachea
0.688 0.312 0.000
S65 Injury of blood vessels at wrist and hand level
0.688 0.312 0.000
Z90.3 Acquired absence of part of stomach
0.688 0.312 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.688 0.312 0.000
H30 Chorioretinal inflammation
0.688 0.312 0.000
M25.72 Osteophyte (Upper arm)
0.688 0.312 0.000
M91-M94 Chondropathies
0.688 0.312 0.000
I74 Arterial embolism and thrombosis
0.687 0.313 0.000
F99 Mental disorder, not otherwise specified
0.686 0.314 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.686 0.314 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.686 0.314 0.000
M50 Cervical disk disorders
0.686 0.314 0.000
S40-S49 Injuries to the shoulder and upper arm
0.685 0.315 0.000
M54.3 Sciatica
0.685 0.315 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.684 0.316 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.684 0.316 0.000
S72 Fracture of femur
0.683 0.317 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.683 0.317 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.683 0.317 0.000
C21.1 Anal canal
0.682 0.318 0.000
F38 Other mood [affective] disorders
0.681 0.319 0.000
F34 Persistent mood [affective] disorders
0.681 0.319 0.000
F30 Manic episode
0.681 0.319 0.000
F39 Unspecified mood [affective] disorder
0.681 0.319 0.000
I44.0 Atrioventricular block, first degree
0.680 0.320 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.679 0.321 0.000
H35.0 Background retinopathy and retinal vascular changes
0.679 0.321 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.679 0.321 0.000
M75.2 Bicipital tendinitis
0.679 0.321 0.000
I51.9 Heart disease, unspecified
0.679 0.321 0.000
M25.76 Osteophyte (Lower leg)
0.676 0.323 0.000
M23.5 Chronic instability of knee
0.676 0.324 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.676 0.324 0.000
H16 Keratitis
0.676 0.324 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.676 0.324 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.675 0.324 0.000
I30 Acute pericarditis
0.675 0.325 0.000
I00-I02 Acute rheumatic fever
0.674 0.326 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.674 0.326 0.000
C17 Malignant neoplasm of small intestine
0.674 0.326 0.000
C23 Malignant neoplasm of gallbladder
0.674 0.326 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.674 0.326 0.000
C21.0 Anus, unspecified
0.674 0.326 0.000
C32 Malignant neoplasm of larynx
0.674 0.326 0.000
H46 Optic neuritis
0.674 0.326 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.673 0.327 0.000
C77.0 Lymph nodes of head, face and neck
0.673 0.327 0.000
M35.0 Sicca syndrome [Sjogren]
0.673 0.327 0.000
I70 Atherosclerosis
0.673 0.327 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.672 0.328 0.000
S61.7 Multiple open wounds of wrist and hand
0.671 0.329 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.671 0.329 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.671 0.329 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.671 0.329 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.671 0.329 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.670 0.330 0.000
M25.71 Osteophyte (Shoulder region)
0.670 0.330 0.000
S01.7 Multiple open wounds of head
0.670 0.330 0.000
Z11.2 Special screening examination for other bacterial diseases
0.670 0.330 0.000
H18 Other disorders of cornea
0.670 0.330 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.669 0.331 0.000
Q35-Q37 Cleft lip and cleft palate
0.669 0.331 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.669 0.331 0.000
C34.8 Overlapping lesion of bronchus and lung
0.669 0.331 0.000
C34.0 Main bronchus
0.669 0.331 0.000
I69 Sequelae of cerebrovascular disease
0.669 0.331 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.668 0.332 0.000
M54.8 Other dorsalgia
0.667 0.332 0.000
M54.6 Pain in thoracic spine
0.667 0.332 0.000
M54.0 Panniculitis affecting regions of neck and back
0.667 0.332 0.000
I71.0 Dissection of aorta [any part]
0.667 0.333 0.000
M51.8 Other specified intervertebral disk disorders
0.667 0.333 0.000
I45.2 Bifascicular block
0.666 0.334 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.666 0.334 0.000
F33.8 Other recurrent depressive disorders
0.665 0.335 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.665 0.335 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.665 0.335 0.000
Z10 Routine general health check-up of defined subpopulation
0.664 0.335 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.664 0.336 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.664 0.336 0.000
Q63 Other congenital malformations of kidney
0.664 0.336 0.000
M22.8 Other disorders of patella
0.664 0.336 0.000
H52.0 Hypermetropia
0.663 0.337 0.000
C79.2 Secondary malignant neoplasm of skin
0.663 0.337 0.000
M23.37 Other meniscus derangements-Capsular lig
0.663 0.337 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.663 0.337 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.663 0.337 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.663 0.337 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.663 0.337 0.000
I67 Other cerebrovascular diseases
0.663 0.337 0.000
I52 Other heart disorders in diseases classified elsewhere
0.663 0.337 0.000
I48 Atrial fibrillation and flutter
0.663 0.337 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.663 0.337 0.000
I41 Myocarditis in diseases classified elsewhere
0.663 0.337 0.000
I40 Acute myocarditis
0.663 0.337 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.663 0.337 0.000
I37 Pulmonary valve disorders
0.663 0.337 0.000
I36 Nonrheumatic tricuspid valve disorders
0.663 0.337 0.000
I32 Pericarditis in diseases classified elsewhere
0.663 0.337 0.000
O40 Polyhydramnios
0.662 0.338 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.661 0.339 0.000
C66 Malignant neoplasm of ureter
0.661 0.339 0.000
C65 Malignant neoplasm of renal pelvis
0.661 0.339 0.000
S01.3 Open wound of ear
0.661 0.339 0.000
F41 Other anxiety disorders
0.661 0.339 0.000
I51.6 Cardiovascular disease, unspecified
0.660 0.340 0.000
I51.5 Myocardial degeneration
0.660 0.340 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.660 0.340 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.660 0.340 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.660 0.340 0.000
I51.0 Cardiac septal defect, acquired
0.660 0.340 0.000
S02 Fracture of skull and facial bones
0.660 0.340 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.660 0.340 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.660 0.340 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.660 0.340 0.000
T42.4 Benzodiazepines
0.659 0.341 0.000
H51 Other disorders of binocular movement
0.659 0.341 0.000
Z81 Family history of mental and behavioural disorders
0.658 0.341 0.000
G90-G99 Other disorders of the nervous system
0.658 0.342 0.000
Z92.9 Personal history of medical treatment, unspecified
0.657 0.343 0.000
Z92.5 Personal history of rehabilitation measures
0.657 0.343 0.000
Q50-Q56 Congenital malformations of genital organs
0.657 0.343 0.000
H33.2 Serous retinal detachment
0.657 0.343 0.000
H33.4 Traction detachment of retina
0.657 0.343 0.000
H33.1 Retinoschisis and retinal cysts
0.657 0.343 0.000
D46 Myelodysplastic syndromes
0.656 0.344 0.000
C80.9 Malignant neoplasm, unspecified
0.656 0.344 0.000
C67.4 Posterior wall of bladder
0.655 0.345 0.000
Z83.5 Family history of eye and ear disorders
0.655 0.345 0.000
F32 Depressive episode
0.654 0.346 0.000
Z13.9 Special screening examination, unspecified
0.654 0.346 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.654 0.346 0.000
M25.37 Other instability of joint (Ankle and foot)
0.653 0.347 0.000
I34.0 Mitral (valve) insufficiency
0.653 0.347 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.653 0.347 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.653 0.347 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.653 0.347 0.000
O44 Placenta praevia
0.651 0.349 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.650 0.349 0.000
S67 Crushing injury of wrist and hand
0.650 0.350 0.000
T92 Sequelae of injuries of upper limb
0.650 0.350 0.000
Q00-Q07 Congenital malformations of the nervous system
0.650 0.350 0.000
C16.0 Cardia
0.650 0.350 0.000
S08 Traumatic amputation of part of head
0.650 0.350 0.000
S07 Crushing injury of head
0.650 0.350 0.000
S05 Injury of eye and orbit
0.650 0.350 0.000
S04 Injury of cranial nerves
0.650 0.350 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.650 0.350 0.000
O62 Abnormalities of forces of labour
0.650 0.350 0.000
V80-V89 Other land transport accidents
0.650 0.350 0.000
Z00.4 General psychiatric examination, not elsewhere classified
0.649 0.351 0.000
M79.7 Fibromyalgia
0.649 0.351 0.000
I72 Other aneurysm
0.649 0.351 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.648 0.352 0.000
M31.9 Necrotising vasculopathy, unspecified
0.648 0.352 0.000
M31.8 Other specified necrotising vasculopathies
0.648 0.352 0.000
M31.7 Microscopic polyangiitis
0.648 0.352 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.648 0.352 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.648 0.352 0.000
M31.3 Wegener's granulomatosis
0.648 0.352 0.000
M31.2 Lethal midline granuloma
0.648 0.352 0.000
M31.1 Thrombotic microangiopathy
0.648 0.352 0.000
M31.0 Hypersensitivity angiitis
0.648 0.352 0.000
M53 Other dorsopathies, not elsewhere classified
0.647 0.352 0.000
H35.8 Other specified retinal disorders
0.647 0.353 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.647 0.353 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.647 0.353 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.647 0.353 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.647 0.353 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.647 0.353 0.000
M54.1 Radiculopathy
0.647 0.353 0.000
S69.9 Unspecified injury of wrist and hand
0.647 0.353 0.000
F03 Unspecified dementia
0.646 0.354 0.000
F60 Specific personality disorders
0.645 0.355 0.000
H17 Corneal scars and opacities
0.645 0.355 0.000
S61.1 Open wound of finger(s) with damage to nail
0.644 0.355 0.000
S60 Superficial injury of wrist and hand
0.644 0.356 0.000
F22 Persistent delusional disorders
0.644 0.356 0.000
T42.1 Iminostilbenes
0.643 0.357 0.000
S01.5 Open wound of lip and oral cavity
0.641 0.359 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.641 0.359 0.000
Z03.0 Observation for suspected tuberculosis
0.641 0.359 0.000
Q61 Cystic kidney disease
0.641 0.359 0.000
I65.2 Occlusion and stenosis of carotid artery
0.640 0.360 0.000
H31.8 Other specified disorders of choroid
0.640 0.360 0.000
O43 Placental disorders
0.640 0.360 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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