TreeWAS – Variant ID: rs4141885

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	0.000	0.008	0.992
E83 Disorders of mineral metabolism	0.000	0.818	0.182
E83.3 Disorders of phosphorus metabolism	0.000	0.858	0.141
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.869	0.130
E83.8 Other disorders of mineral metabolism	0.000	0.869	0.130
E83.2 Disorders of zinc metabolism	0.000	0.869	0.130
E83.0 Disorders of copper metabolism	0.000	0.869	0.130
E83.4 Disorders of magnesium metabolism	0.000	0.916	0.084
E83.5 Disorders of calcium metabolism	0.000	0.934	0.066
G43.9 Migraine, unspecified	0.065	0.935	0.000
G43 Migraine	0.032	0.968	0.000
G43.1 Migraine with aura [classical migraine]	0.026	0.974	0.000
G43.3 Complicated migraine	0.023	0.977	0.000
G43.2 Status migrainosus	0.023	0.977	0.000
G43.0 Migraine without aura [common migraine]	0.023	0.977	0.000
G43.8 Other migraine	0.021	0.978	0.000
F31 Bipolar affective disorder	0.000	0.988	0.012
F33.9 Recurrent depressive disorder, unspecified	0.000	0.989	0.011
F31.9 Bipolar affective disorder, unspecified	0.000	0.989	0.011
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.990	0.010
F30-F39 Mood [affective] disorders	0.000	0.990	0.010
F33 Recurrent depressive disorder	0.000	0.990	0.010
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.990	0.010
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.990	0.010
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.991	0.009
F32 Depressive episode	0.000	0.991	0.009
E70-E90 Metabolic disorders	0.000	0.991	0.009
F31.8 Other bipolar affective disorders	0.000	0.991	0.008
F31.7 Bipolar affective disorder, currently in remission	0.000	0.991	0.008
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.991	0.008
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.992	0.008
F32.0 Mild depressive episode	0.000	0.992	0.008
J38.7 Other diseases of larynx	0.008	0.992	0.000
F32.1 Moderate depressive episode	0.000	0.992	0.008
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.008	0.992	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.992	0.008
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.992	0.008
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.992	0.008
J38.3 Other diseases of vocal cords	0.008	0.992	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.992	0.007
E88 Other metabolic disorders	0.000	0.992	0.008
J38.5 Laryngeal spasm	0.007	0.992	0.000
F38 Other mood [affective] disorders	0.000	0.993	0.007
F33.8 Other recurrent depressive disorders	0.000	0.993	0.007
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.993	0.007
J38.4 Oedema of larynx	0.007	0.993	0.000
F34 Persistent mood [affective] disorders	0.000	0.993	0.007
F30 Manic episode	0.000	0.993	0.007
J38.2 Nodules of vocal cords	0.007	0.993	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.993	0.007
F39 Unspecified mood [affective] disorder	0.000	0.993	0.007
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.993	0.007
F32.8 Other depressive episodes	0.000	0.993	0.007
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.993	0.007
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.993	0.007
E84 Cystic fibrosis	0.000	0.993	0.006
E79 Disorders of purine and pyrimidine metabolism	0.000	0.993	0.006
E77 Disorders of glycoprotein metabolism	0.000	0.993	0.006
E76 Disorders of glycosaminoglycan metabolism	0.000	0.993	0.006
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.993	0.006
E72 Other disorders of amino-acid metabolism	0.000	0.993	0.006
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.993	0.006
E70 Disorders of aromatic amino-acid metabolism	0.000	0.993	0.006
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.993	0.006
E89.0 Postprocedural hypothyroidism	0.000	0.994	0.006
E85 Amyloidosis	0.000	0.994	0.006
E74 Other disorders of carbohydrate metabolism	0.000	0.994	0.006
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.994	0.006
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.994	0.006
E73 Lactose intolerance	0.000	0.994	0.006
J38.6 Stenosis of larynx	0.006	0.994	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.994	0.006
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.994	0.006
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.994	0.006
E89.5 Postprocedural testicular hypofunction	0.000	0.994	0.006
E89.4 Postprocedural ovarian failure	0.000	0.994	0.006
E89.1 Postprocedural hypoinsulinaemia	0.000	0.994	0.006
J38.0 Paralysis of vocal cords and larynx	0.006	0.994	0.000
E88.9 Metabolic disorder, unspecified	0.000	0.994	0.006
E88.8 Other specified metabolic disorders	0.000	0.994	0.006
E88.3 Tumour lysis syndrome	0.000	0.994	0.006
E88.2 Lipomatosis, not elsewhere classified	0.000	0.994	0.006
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.994	0.006
F38.8 Other specified mood [affective] disorders	0.000	0.994	0.005
F38.1 Other recurrent mood [affective] disorders	0.000	0.994	0.005
F38.0 Other single mood [affective] disorders	0.000	0.994	0.005
F30.0 Hypomania	0.000	0.994	0.005
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.994	0.005
F34.8 Other persistent mood [affective] disorders	0.000	0.994	0.005
F34.0 Cyclothymia	0.000	0.994	0.005
F30.8 Other manic episodes	0.000	0.994	0.005
F30.2 Mania with psychotic symptoms	0.000	0.994	0.005
F30.1 Mania without psychotic symptoms	0.000	0.994	0.005
F34.1 Dysthymia	0.000	0.995	0.005
F30.9 Manic episode, unspecified	0.000	0.995	0.005
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.995	0.005
E85.4 Organ-limited amyloidosis	0.000	0.995	0.005
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.995	0.005
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.995	0.005
E70.3 Albinism	0.000	0.995	0.005
E70.2 Disorders of tyrosine metabolism	0.000	0.995	0.005
E70.1 Other hyperphenylalaninaemias	0.000	0.995	0.005
E70.0 Classical phenylketonuria	0.000	0.995	0.005
E71.3 Disorders of fatty-acid metabolism	0.000	0.995	0.005
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.995	0.005
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.995	0.005
E71.0 Maple-syrup-urine disease	0.000	0.995	0.005
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.995	0.005
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.995	0.005
E72.5 Disorders of glycine metabolism	0.000	0.995	0.005
E72.4 Disorders of ornithine metabolism	0.000	0.995	0.005
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.995	0.005
E72.2 Disorders of urea cycle metabolism	0.000	0.995	0.005
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.995	0.005
E72.0 Disorders of amino-acid transport	0.000	0.995	0.005
E75.6 Lipid storage disorder, unspecified	0.000	0.995	0.005
E75.5 Other lipid storage disorders	0.000	0.995	0.005
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.995	0.005
E75.3 Sphingolipidosis, unspecified	0.000	0.995	0.005
E75.2 Other sphingolipidosis	0.000	0.995	0.005
E75.1 Other gangliosidosis	0.000	0.995	0.005
E75.0 GM2 gangliosidosis	0.000	0.995	0.005
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.995	0.005
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.995	0.005
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.995	0.005
E76.2 Other mucopolysaccharidoses	0.000	0.995	0.005
E76.1 Mucopolysaccharidosis, type II	0.000	0.995	0.005
E76.0 Mucopolysaccharidosis, type I	0.000	0.995	0.005
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.995	0.005
E77.8 Other disorders of glycoprotein metabolism	0.000	0.995	0.005
E77.1 Defects in glycoprotein degradation	0.000	0.995	0.005
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.995	0.005
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.995	0.005
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.995	0.005
E79.1 Lesch-Nyhan syndrome	0.000	0.995	0.005
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.995	0.005
E84.9 Cystic fibrosis, unspecified	0.000	0.995	0.005
E84.8 Cystic fibrosis with other manifestations	0.000	0.995	0.005
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.995	0.005
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.995	0.005
J38.1 Polyp of vocal cord and larynx	0.005	0.995	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.995	0.005
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.995	0.005
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.995	0.005
E74.2 Disorders of galactose metabolism	0.000	0.995	0.005
E74.1 Disorders of fructose metabolism	0.000	0.995	0.005
E74.0 Glycogen storage disease	0.000	0.995	0.005
E85.8 Other amyloidosis	0.000	0.995	0.005
E85.3 Secondary systemic amyloidosis	0.000	0.995	0.005
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.995	0.005
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.995	0.005
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.995	0.005
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.995	0.005
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.995	0.005
E73.8 Other lactose intolerance	0.000	0.995	0.004
E73.1 Secondary lactase deficiency	0.000	0.995	0.004
E73.0 Congenital lactase deficiency	0.000	0.995	0.004
E85.9 Amyloidosis, unspecified	0.000	0.995	0.004
E89.3 Postprocedural hypopituitarism	0.000	0.995	0.004
E73.9 Lactose intolerance, unspecified	0.000	0.996	0.004
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.996	0.004
E80.6 Other disorders of bilirubin metabolism	0.000	0.996	0.004
E80.5 Crigler-Najjar syndrome	0.000	0.996	0.004
E80.3 Defects of catalase and peroxydase	0.000	0.996	0.004
E80.2 Other porphyria	0.000	0.996	0.004
E80.1 Porphyria cutanea tarda	0.000	0.996	0.004
E80.0 Hereditary erythropoietic porphyria	0.000	0.996	0.004
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.004	0.996	0.000
K58.9 Irritable bowel syndrome without diarrhoea	0.004	0.996	0.000
C71.9 Brain, unspecified	0.000	0.996	0.004
M43.1 Spondylolisthesis	0.000	0.996	0.004
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.996	0.004
C71.1 Frontal lobe	0.000	0.996	0.004
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.996	0.004
C71 Malignant neoplasm of brain	0.000	0.996	0.003
D25.0 Submucous leiomyoma of uterus	0.000	0.997	0.003
C56 Malignant neoplasm of ovary	0.003	0.997	0.000
C71.2 Temporal lobe	0.000	0.997	0.003
M43.19 Spondylolisthesis (Site unspecified)	0.000	0.997	0.003
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M43.15 Spondylolisthesis (Thoracolumbar region)	0.000	0.997	0.003
M43.14 Spondylolisthesis (Thoracic region)	0.000	0.997	0.003
M43.13 Spondylolisthesis (Cervicothoracic region)	0.000	0.997	0.003
M43.12 Spondylolisthesis (Cervical region)	0.000	0.997	0.003
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.000	0.997	0.003
M43.10 Spondylolisthesis (Multiple sites in spine)	0.000	0.997	0.003
E86 Volume depletion	0.000	0.997	0.003
C71.3 Parietal lobe	0.000	0.997	0.003
E80.4 Gilbert's syndrome	0.000	0.997	0.003
C71.7 Brain stem	0.000	0.997	0.003
C71.6 Cerebellum	0.000	0.997	0.003
C71.5 Cerebral ventricle	0.000	0.997	0.003
C71.4 Occipital lobe	0.000	0.997	0.003
C71.0 Cerebrum, except lobes and ventricles	0.000	0.997	0.003
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.003	0.997	0.000
C71.8 Overlapping lesion of brain	0.000	0.997	0.003
Z63.4 Disappearance and death of family member	0.003	0.997	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.997	0.003
C34.3 Lower lobe, bronchus or lung	0.000	0.997	0.003
D12.3 Transverse colon	0.000	0.997	0.003
Z58.1 Exposure to air pollution	0.003	0.997	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.003	0.997	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.997	0.002
Z63 Other problems related to primary support group, including family circumstances	0.002	0.998	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.002	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.002	0.998	0.000
I67.9 Cerebrovascular disease, unspecified	0.002	0.998	0.000
S42.00 Fracture of clavicle (closed)	0.000	0.998	0.002
D25.2 Subserosal leiomyoma of uterus	0.000	0.998	0.002
N88.8 Other specified noninflammatory disorders of cervix uteri	0.002	0.998	0.000
Z63.0 Problems in relationship with spouse or partner	0.002	0.998	0.000
Z63.8 Other specified problems related to primary support group	0.002	0.998	0.000
Z63.7 Other stressful life events affecting family and household	0.002	0.998	0.000
K04.8 Radicular cyst	0.002	0.998	0.000
D25 Leiomyoma of uterus	0.000	0.998	0.002
G40-G47 Episodic and paroxysmal disorders	0.002	0.998	0.000
K58 Irritable bowel syndrome	0.002	0.998	0.000
L30.9 Dermatitis, unspecified	0.000	0.998	0.002
N64.5 Other signs and symptoms in breast	0.002	0.998	0.000
Z63.9 Problem related to primary support group, unspecified	0.002	0.998	0.000
Z63.6 Dependent relative needing care at home	0.002	0.998	0.000
Z63.5 Disruption of family by separation and divorce	0.002	0.998	0.000
Z63.3 Absence of family member	0.002	0.998	0.000
Z63.2 Inadequate family support	0.002	0.998	0.000
Z63.1 Problems in relationship with parents and in-laws	0.002	0.998	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.998	0.002
D25.1 Intramural leiomyoma of uterus	0.000	0.998	0.002
Z58 Problems related to physical environment	0.002	0.998	0.000
H43.3 Other vitreous opacities	0.002	0.998	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.002	0.998	0.000
M43 Other deforming dorsopathies	0.000	0.998	0.002
S42.3 Fracture of shaft of humerus	0.000	0.998	0.002
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.998	0.002
G46 Vascular syndromes of brain in cerebrovascular diseases	0.002	0.998	0.000
S42.0 Fracture of clavicle	0.000	0.998	0.002
G41 Status epilepticus	0.002	0.998	0.000
Z58.9 Problem related to physical environment, unspecified	0.002	0.998	0.000
Z58.8 Other problems related to physical environment	0.002	0.998	0.000
Z58.7 Exposure to tobacco smoke	0.002	0.998	0.000
Z58.6 Inadequate drinking-water supply	0.002	0.998	0.000
Z58.5 Exposure to other pollution	0.002	0.998	0.000
Z58.4 Exposure to radiation	0.002	0.998	0.000
Z58.3 Exposure to soil pollution	0.002	0.998	0.000
Z58.2 Exposure to water pollution	0.002	0.998	0.000
Z58.0 Exposure to noise	0.002	0.998	0.000
O48 Prolonged pregnancy	0.000	0.998	0.002
C77.0 Lymph nodes of head, face and neck	0.000	0.998	0.002
I83 Varicose veins of lower extremities	0.000	0.998	0.002
H40.2 Primary angle-closure glaucoma	0.000	0.998	0.002
M43.9 Deforming dorsopathy, unspecified	0.000	0.998	0.001
M43.8 Other specified deforming dorsopathies	0.000	0.998	0.001
M43.5 Other recurrent vertebral subluxation	0.000	0.998	0.001
M43.4 Other recurrent atlantoaxial subluxation	0.000	0.998	0.001
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.000	0.998	0.001
M43.2 Other fusion of spine	0.000	0.998	0.001
D45 Polycythaemia vera	0.000	0.998	0.002
G44 Other headache syndromes	0.002	0.998	0.000
S42.31 Fracture of shaft of humerus (open)	0.000	0.998	0.001
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.002	0.998	0.000
L40.0 Psoriasis vulgaris	0.002	0.998	0.000
C69.3 Choroid	0.001	0.998	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.002	0.998	0.000
C69.9 Eye, unspecified	0.001	0.998	0.000
R61.0 Localised hyperhidrosis	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M43.6 Torticollis	0.000	0.998	0.001
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.001	0.998	0.000
G46.7 Other lacunar syndromes	0.001	0.998	0.000
G46.6 Pure sensory lacunar syndrome	0.001	0.998	0.000
G46.5 Pure motor lacunar syndrome	0.001	0.998	0.000
G46.4 Cerebellar stroke syndrome	0.001	0.998	0.000
G46.3 Brain stem stroke syndrome	0.001	0.998	0.000
G46.2 Posterior cerebral artery syndrome	0.001	0.998	0.000
G46.1 Anterior cerebral artery syndrome	0.001	0.998	0.000
G46.0 Middle cerebral artery syndrome	0.001	0.998	0.000
G47.4 Narcolepsy and cataplexy	0.002	0.998	0.000
N20.1 Calculus of ureter	0.002	0.998	0.000
S42.01 Fracture of clavicle (open)	0.000	0.998	0.001
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
G41.8 Other status epilepticus	0.001	0.998	0.000
G41.2 Complex partial status epilepticus	0.001	0.998	0.000
G41.1 Petit mal status epilepticus	0.001	0.998	0.000
G41.0 Grand mal status epilepticus	0.001	0.998	0.000
Z57.3 Occupational exposure to other air contaminants	0.001	0.998	0.000
M43.0 Spondylolysis	0.000	0.998	0.001
Z98.0 Intestinal bypass and anastomosis status	0.000	0.998	0.002
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.002	0.998	0.000
G41.9 Status epilepticus, unspecified	0.001	0.998	0.000
K55.2 Angiodysplasia of colon	0.002	0.998	0.000
R61.9 Hyperhidrosis, unspecified	0.002	0.998	0.000
G44.2 Tension-type headache	0.001	0.998	0.000
Z73.6 Limitation of activities due to disability	0.001	0.998	0.000
C69 Malignant neoplasm of eye and adnexa	0.001	0.998	0.000
M43.29 Other fusion of spine (Site unspecified)	0.000	0.999	0.001
M43.28 Other fusion of spine (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M43.27 Other fusion of spine (Lumbosacral region)	0.000	0.999	0.001
M43.26 Other fusion of spine (Lumbar region)	0.000	0.999	0.001
M43.25 Other fusion of spine (Thoracolumbar region)	0.000	0.999	0.001
M43.24 Other fusion of spine (Thoracic region)	0.000	0.999	0.001
M43.23 Other fusion of spine (Cervicothoracic region)	0.000	0.999	0.001
M43.22 Other fusion of spine (Cervical region)	0.000	0.999	0.001
M43.21 Other fusion of spine (Occipito-atlanto-axial region)	0.000	0.999	0.001
M43.20 Other fusion of spine (Multiple sites in spine)	0.000	0.999	0.001
M43.39 Recurrent atlantoaxial subluxation with myelopathy (Site unspecified)	0.000	0.999	0.001
M43.38 Recurrent atlantoaxial subluxation with myelopathy (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M43.37 Recurrent atlantoaxial subluxation with myelopathy (Lumbosacral region)	0.000	0.999	0.001
M43.36 Recurrent atlantoaxial subluxation with myelopathy (Lumbar region)	0.000	0.999	0.001
M43.35 Recurrent atlantoaxial subluxation with myelopathy (Thoracolumbar region)	0.000	0.999	0.001
M43.34 Recurrent atlantoaxial subluxation with myelopathy (Thoracic region)	0.000	0.999	0.001
M43.33 Recurrent atlantoaxial subluxation with myelopathy (Cervicothoracic region)	0.000	0.999	0.001
M43.32 Recurrent atlantoaxial subluxation with myelopathy (Cervical region)	0.000	0.999	0.001
M43.31 Recurrent atlantoaxial subluxation with myelopathy (Occipito-atlanto-axial region)	0.000	0.999	0.001
M43.30 Recurrent atlantoaxial subluxation with myelopathy (Multiple sites in spine)	0.000	0.999	0.001
M43.49 Other recurrent atlantoaxial subluxation-Site unspe	0.000	0.999	0.001
M43.48 Other recurrent atlantoaxial subluxation-Sacral/sacrococ	0.000	0.999	0.001
M43.47 Other recurrent atlantoaxial subluxation-Lumbosacral	0.000	0.999	0.001
M43.46 Other recurrent atlantoaxial subluxation-Lumbar	0.000	0.999	0.001
M43.45 Other recurrent atlantoaxial subluxation-Thoracolumbar	0.000	0.999	0.001
M43.44 Other recurrent atlantoaxial subluxation-Thoracic	0.000	0.999	0.001
M43.43 Other recurrent atlantoaxial subluxation-Cervicothoracic	0.000	0.999	0.001
M43.42 Other recurrent atlantoaxial subluxation-Cervical	0.000	0.999	0.001
M43.41 Other recurrent atlantoaxial subluxation-Occipit-atl-axl	0.000	0.999	0.001
M43.40 Other recurrent atlantoaxial subluxation-Mult site	0.000	0.999	0.001
M43.59 Other recurrent vertebral subluxation (Site unspecified)	0.000	0.999	0.001
M43.58 Other recurrent vertebral subluxation (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M43.57 Other recurrent vertebral subluxation (Lumbosacral region)	0.000	0.999	0.001
M43.56 Other recurrent vertebral subluxation (Lumbar region)	0.000	0.999	0.001
M43.55 Other recurrent vertebral subluxation (Thoracolumbar region)	0.000	0.999	0.001
M43.54 Other recurrent vertebral subluxation (Thoracic region)	0.000	0.999	0.001
M43.53 Other recurrent vertebral subluxation (Cervicothoracic region)	0.000	0.999	0.001
M43.52 Other recurrent vertebral subluxation (Cervical region)	0.000	0.999	0.001
M43.51 Other recurrent vertebral subluxation-Occipit-atl-axl	0.000	0.999	0.001
M43.50 Other recurrent vertebral subluxation (Multiple sites in spine)	0.000	0.999	0.001
M43.89 Other specified deforming dorsopathies (Site unspecified)	0.000	0.999	0.001
M43.88 Other specified deforming dorsopathies (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M43.87 Other specified deforming dorsopathies (Lumbosacral region)	0.000	0.999	0.001
M43.86 Other specified deforming dorsopathies (Lumbar region)	0.000	0.999	0.001
M43.85 Other specified deforming dorsopathies (Thoracolumbar region)	0.000	0.999	0.001
M43.84 Other specified deforming dorsopathies (Thoracic region)	0.000	0.999	0.001
M43.83 Other specified deforming dorsopathies (Cervicothoracic region)	0.000	0.999	0.001
M43.82 Other specified deforming dorsopathies (Cervical region)	0.000	0.999	0.001
M43.81 Other specified deforming dorsopathies (Occipito-atlanto-axial region)	0.000	0.999	0.001
M43.80 Other specified deforming dorsopathies (Multiple sites in spine)	0.000	0.999	0.001
M43.99 Deforming dorsopathy, unspecified (Site unspecified)	0.000	0.999	0.001
M43.98 Deforming dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M43.97 Deforming dorsopathy, unspecified (Lumbosacral region)	0.000	0.999	0.001
M43.96 Deforming dorsopathy, unspecified (Lumbar region)	0.000	0.999	0.001
M43.95 Deforming dorsopathy, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M43.94 Deforming dorsopathy, unspecified (Thoracic region)	0.000	0.999	0.001
M43.93 Deforming dorsopathy, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M43.92 Deforming dorsopathy, unspecified (Cervical region)	0.000	0.999	0.001
M43.91 Deforming dorsopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
M43.90 Deforming dorsopathy, unspecified (Multiple sites in spine)	0.000	0.999	0.001
G44.4 Drug-induced headache, not elsewhere classified	0.001	0.999	0.000
G44.3 Chronic posttraumatic headache	0.001	0.999	0.000
G44.1 Vascular headache, not elsewhere classified	0.001	0.999	0.000
I67.1 Cerebral aneurysm, nonruptured	0.001	0.999	0.000
G47 Sleep disorders	0.001	0.999	0.000
Q66.7 Pes cavus	0.001	0.999	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.001	0.999	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.001	0.999	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.001	0.999	0.000
I67 Other cerebrovascular diseases	0.001	0.999	0.000
Z57 Occupational exposure to risk-factors	0.001	0.999	0.000
M43.69 Torticollis-Site unspe	0.000	0.999	0.001
M43.68 Torticollis-Sacral/sacrococ	0.000	0.999	0.001
M43.67 Torticollis-Lumbosacral	0.000	0.999	0.001
M43.66 Torticollis-Lumbar	0.000	0.999	0.001
M43.65 Torticollis-Thoracolumbar	0.000	0.999	0.001
M43.64 Torticollis-Thoracic	0.000	0.999	0.001
M43.63 Torticollis-Cervicothoracic	0.000	0.999	0.001
M43.61 Torticollis-Occipit-atl-axl	0.000	0.999	0.001
M43.60 Torticollis-Mult site	0.000	0.999	0.001
C53.9 Cervix uteri, unspecified	0.001	0.999	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.999	0.001
N42.9 Disorder of prostate, unspecified	0.000	0.999	0.001
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.001	0.999	0.000
Z01.8 Other specified special examinations	0.000	0.999	0.001
M43.09 Spondylolysis (Site unspecified)	0.000	0.999	0.001
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M43.07 Spondylolysis (Lumbosacral region)	0.000	0.999	0.001
M43.06 Spondylolysis (Lumbar region)	0.000	0.999	0.001
M43.05 Spondylolysis (Thoracolumbar region)	0.000	0.999	0.001
M43.04 Spondylolysis (Thoracic region)	0.000	0.999	0.001
M43.03 Spondylolysis (Cervicothoracic region)	0.000	0.999	0.001
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.000	0.999	0.001
M43.00 Spondylolysis (Multiple sites in spine)	0.000	0.999	0.001
S02.80 Fractures of other skull and facial bones (closed)	0.001	0.999	0.000
N64.1 Fat necrosis of breast	0.001	0.999	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.999	0.001
C15.9 Oesophagus, unspecified	0.001	0.999	0.000
G44.0 Cluster headache syndrome	0.001	0.999	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.001	0.999	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.999	0.001
S42 Fracture of shoulder and upper arm	0.000	0.999	0.001
Z65 Problems related to other psychosocial circumstances	0.001	0.999	0.000
Z62 Other problems related to upbringing	0.001	0.999	0.000
Z61 Problems related to negative life events in childhood	0.001	0.999	0.000
Z59 Problems related to housing and economic circumstances	0.001	0.999	0.000
Z55 Problems related to education and literacy	0.001	0.999	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.999	0.001
J03.9 Acute tonsillitis, unspecified	0.001	0.999	0.000
M19.0 Primary arthrosis of other joints	0.000	0.999	0.001
N13.3 Other and unspecified hydronephrosis	0.001	0.999	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.999	0.001
Z12.5 Special screening examination for neoplasm of prostate	0.001	0.999	0.000
Q66 Congenital deformities of feet	0.001	0.999	0.000
M43.62 Torticollis-Cervical	0.000	0.999	0.001
C69.8 Overlapping lesion of eye and adnexa	0.001	0.999	0.000
C69.6 Orbit	0.001	0.999	0.000
C69.5 Lachrymal gland and duct	0.001	0.999	0.000
C69.4 Ciliary body	0.001	0.999	0.000
C69.2 Retina	0.001	0.999	0.000
C69.1 Cornea	0.001	0.999	0.000
C69.0 Conjunctiva	0.001	0.999	0.000
G44.8 Other specified headache syndromes	0.001	0.999	0.000
G47.2 Disorders of the sleep-wake schedule	0.001	0.999	0.000
I67.2 Cerebral atherosclerosis	0.001	0.999	0.000
K62.0 Anal polyp	0.000	0.999	0.001
D21 Other benign neoplasms of connective and other soft tissue	0.001	0.999	0.000
D21.5 Connective and other soft tissue of pelvis	0.001	0.999	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.999	0.001
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.001	0.999	0.000
R68.8 Other specified general symptoms and signs	0.000	0.999	0.001
W10.8 Other specified place	0.000	0.999	0.001
C34 Malignant neoplasm of bronchus and lung	0.000	0.999	0.001
Z73 Problems related to life-management difficulty	0.001	0.999	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.999	0.001
S42.4 Fracture of lower end of humerus	0.000	0.999	0.001
N64 Other disorders of breast	0.001	0.999	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.999	0.001
I67.7 Cerebral arteritis, not elsewhere classified	0.001	0.999	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.001	0.999	0.000
I67.5 Moyamoya disease	0.001	0.999	0.000
I67.4 Hypertensive encephalopathy	0.001	0.999	0.000
I67.3 Progressive vascular leukoencephalopathy	0.001	0.999	0.000
M87.9 Osteonecrosis, unspecified	0.001	0.999	0.000
O63.1 Prolonged second stage (of labour)	0.000	0.999	0.001
Z57.9 Occupational exposure to unspecified risk-factor	0.001	0.999	0.000
Z57.8 Occupational exposure to other risk-factors	0.001	0.999	0.000
Z57.7 Occupational exposure to vibration	0.001	0.999	0.000
Z57.6 Occupational exposure to extreme temperature	0.001	0.999	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.001	0.999	0.000
Z57.1 Occupational exposure to radiation	0.001	0.999	0.000
Z57.0 Occupational exposure to noise	0.001	0.999	0.000
Z64 Problems related to certain psychosocial circumstances	0.001	0.999	0.000
Z56 Problems related to employment and unemployment	0.001	0.999	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.999	0.001
D21.0 Connective and other soft tissue of head, face and neck	0.001	0.999	0.000
G47.3 Sleep apnoea	0.001	0.999	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.001	0.999	0.000
N88.1 Old laceration of cervix uteri	0.001	0.999	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.001	0.999	0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.001	0.999	0.000
N88 Other noninflammatory disorders of cervix uteri	0.001	0.999	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.999	0.001
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.001	0.999	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.999	0.001
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.999	0.001
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.999	0.001
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.999	0.001
Z55.9 Problems relating to education and literacy, unspecified	0.001	0.999	0.000
Z55.8 Other problems relating to education and literacy	0.001	0.999	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.001	0.999	0.000
Z55.3 Underachievement in school	0.001	0.999	0.000
Z55.2 Failed examinations	0.001	0.999	0.000
Z55.1 Schooling unavailable and unattainable	0.001	0.999	0.000
Z55.0 Illiteracy and low-level literacy	0.001	0.999	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.001	0.999	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.001	0.999	0.000
Z59.7 Insufficient social insurance and welfare support	0.001	0.999	0.000
Z59.6 Low income	0.001	0.999	0.000
Z59.5 Extreme poverty	0.001	0.999	0.000
Z59.4 Lack of adequate food	0.001	0.999	0.000
Z59.3 Problems related to living in residential institution	0.001	0.999	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.001	0.999	0.000
Z59.1 Inadequate housing	0.001	0.999	0.000
Z59.0 Homelessness	0.001	0.999	0.000
Z61.9 Negative life events in childhood, unspecified	0.001	0.999	0.000
Z61.8 Other negative life events in childhood	0.001	0.999	0.000
Z61.7 Personal frightening experience in childhood	0.001	0.999	0.000
Z61.6 Problems related to alleged physical abuse of child	0.001	0.999	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.001	0.999	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.001	0.999	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.001	0.999	0.000
Z61.2 Altered pattern of family relationships in childhood	0.001	0.999	0.000
Z61.1 Removal from home in childhood	0.001	0.999	0.000
Z61.0 Loss of love relationship in childhood	0.001	0.999	0.000
Z62.9 Problem related to upbringing, unspecified	0.001	0.999	0.000
Z62.8 Other specified problems related to upbringing	0.001	0.999	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.001	0.999	0.000
Z62.5 Other problems related to neglect in upbringing	0.001	0.999	0.000
Z62.4 Emotional neglect of child	0.001	0.999	0.000
Z62.3 Hostility towards and scapegoating of child	0.001	0.999	0.000
Z62.2 Institutional upbringing	0.001	0.999	0.000
Z62.1 Parental overprotection	0.001	0.999	0.000
Z62.0 Inadequate parental supervision and control	0.001	0.999	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.001	0.999	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.001	0.999	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations