TreeWAS – Variant ID: rs4150581

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C34.9 Bronchus or lung, unspecified	0.000	0.535	0.465
C34 Malignant neoplasm of bronchus and lung	0.000	0.593	0.407
C34.2 Middle lobe, bronchus or lung	0.000	0.620	0.380
C34.0 Main bronchus	0.000	0.624	0.376
C34.8 Overlapping lesion of bronchus and lung	0.000	0.722	0.278
C34.3 Lower lobe, bronchus or lung	0.000	0.750	0.250
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.798	0.202
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.840	0.160
C34.1 Upper lobe, bronchus or lung	0.000	0.842	0.158
C31 Malignant neoplasm of accessory sinuses	0.000	0.849	0.151
C37 Malignant neoplasm of thymus	0.000	0.850	0.150
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.851	0.149
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.855	0.145
C32 Malignant neoplasm of larynx	0.000	0.863	0.137
C33 Malignant neoplasm of trachea	0.000	0.864	0.136
C38.3 Mediastinum, part unspecified	0.000	0.875	0.125
C32.0 Glottis	0.000	0.875	0.125
C38.4 Pleura	0.000	0.879	0.121
C31.0 Maxillary sinus	0.000	0.885	0.115
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.885	0.115
C38.2 Posterior mediastinum	0.000	0.885	0.115
C38.1 Anterior mediastinum	0.000	0.885	0.115
C38.0 Heart	0.000	0.885	0.115
C30.0 Nasal cavity	0.000	0.889	0.111
C31.9 Accessory sinus, unspecified	0.000	0.891	0.108
C31.8 Overlapping lesion of accessory sinuses	0.000	0.891	0.108
C31.3 Sphenoidal sinus	0.000	0.891	0.108
C31.2 Frontal sinus	0.000	0.891	0.108
C31.1 Ethmoidal sinus	0.000	0.891	0.108
C30.1 Middle ear	0.000	0.893	0.107
C39.9 Ill-defined sites within the respiratory system	0.000	0.896	0.104
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.896	0.104
C39.0 Upper respiratory tract, part unspecified	0.000	0.896	0.104
C32.8 Overlapping lesion of larynx	0.000	0.902	0.098
C32.3 Laryngeal cartilage	0.000	0.902	0.098
C32.2 Subglottis	0.000	0.902	0.098
C32.9 Larynx, unspecified	0.000	0.919	0.080
D86 Sarcoidosis	0.042	0.958	0.000
D86.9 Sarcoidosis, unspecified	0.041	0.959	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.959	0.041
D86.0 Sarcoidosis of lung	0.041	0.959	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.960	0.040
T40.6 Other and unspecified narcotics	0.000	0.961	0.039
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.962	0.038
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.962	0.038
T40.2 Other opioids	0.000	0.962	0.038
D86.1 Sarcoidosis of lymph nodes	0.038	0.962	0.000
C32.1 Supraglottis	0.002	0.963	0.035
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.036	0.964	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.965	0.035
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.965	0.035
T36 Poisoning by systemic antibiotics	0.000	0.966	0.034
T40.4 Other synthetic narcotics	0.000	0.967	0.033
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.967	0.033
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.967	0.033
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.968	0.032
T36.0 Penicillins	0.000	0.969	0.031
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.969	0.031
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.970	0.030
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.970	0.030
D86.3 Sarcoidosis of skin	0.030	0.970	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.970	0.029
T40.8 Lysergide [LSD]	0.000	0.970	0.029
T40.7 Cannabis (derivatives)	0.000	0.970	0.029
T40.1 Heroin	0.000	0.970	0.029
T40.0 Opium	0.000	0.970	0.029
T40.3 Methadone	0.000	0.971	0.029
T40.5 Cocaine	0.000	0.971	0.029
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.971	0.029
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.971	0.029
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.971	0.029
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.971	0.029
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.971	0.029
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.971	0.029
T44.0 Anticholinesterase agents	0.000	0.971	0.029
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.971	0.029
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.972	0.028
T47.0 Histamine H(2)-receptor antagonists	0.000	0.972	0.028
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.973	0.027
T36.3 Macrolides	0.000	0.974	0.026
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.974	0.026
T36.4 Tetracyclines	0.000	0.974	0.026
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.974	0.026
T47.2 Stimulant laxatives	0.000	0.974	0.026
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.974	0.026
D86.8 Sarcoidosis of other and combined sites	0.025	0.974	0.000
T50.4 Drugs affecting uric acid metabolism	0.000	0.975	0.025
T50.7 Analeptics and opioid receptor antagonists	0.000	0.975	0.025
T50.5 Appetite depressants	0.000	0.975	0.025
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.975	0.025
T50.0 Mineralocorticoids and their antagonists	0.000	0.975	0.025
T50.1 Loop [high-ceiling] diuretics	0.000	0.975	0.025
T36.9 Systemic antibiotic, unspecified	0.000	0.975	0.025
T36.8 Other systemic antibiotics	0.000	0.975	0.025
T36.7 Antifungal antibiotics, systemically used	0.000	0.975	0.025
T36.6 Rifamycins	0.000	0.975	0.025
T36.5 Aminoglycosides	0.000	0.975	0.025
T36.2 Chloramphenicol group	0.000	0.975	0.025
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.975	0.025
T46.1 Calcium-channel blockers	0.000	0.975	0.025
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.975	0.025
T50.8 Diagnostic agents	0.000	0.976	0.024
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.976	0.024
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.976	0.024
T47.7 Emetics	0.000	0.976	0.024
T47.5 Digestants	0.000	0.976	0.024
T47.3 Saline and osmotic laxatives	0.000	0.976	0.024
D80-D89 Certain disorders involving the immune mechanism	0.024	0.976	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.976	0.023
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.977	0.023
T42.1 Iminostilbenes	0.000	0.977	0.023
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.977	0.022
T47.4 Other laxatives	0.000	0.978	0.022
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.978	0.022
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.978	0.022
T46.7 Peripheral vasodilators	0.000	0.978	0.022
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.978	0.022
T37.5 Antiviral drugs	0.000	0.978	0.022
T37.4 Anthelminthics	0.000	0.978	0.022
T37.3 Other antiprotozoal drugs	0.000	0.978	0.022
T37.1 Antimycobacterial drugs	0.000	0.978	0.022
T37.0 Sulphonamides	0.000	0.978	0.022
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.978	0.022
T47.6 Antidiarrhoeal drugs	0.000	0.978	0.022
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.979	0.021
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.979	0.021
T48.5 Anti-common-cold drugs	0.000	0.979	0.021
T48.4 Expectorants	0.000	0.979	0.021
T48.3 Antitussives	0.000	0.979	0.021
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.979	0.021
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.979	0.021
T48.0 Oxytocic drugs	0.000	0.979	0.021
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.979	0.021
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.979	0.021
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.979	0.020
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.979	0.020
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.980	0.020
T49.9 Topical agent, unspecified	0.000	0.980	0.020
T49.8 Other topical agents	0.000	0.980	0.020
T49.7 Dental drugs, topically applied	0.000	0.980	0.020
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.980	0.020
T49.5 Ophthalmological drugs and preparations	0.000	0.980	0.020
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.980	0.020
T49.3 Emollients, demulcents and protectants	0.000	0.980	0.020
T49.2 Local astringents and local detergents	0.000	0.980	0.020
T49.1 Antipruritics	0.000	0.980	0.020
T42.3 Barbiturates	0.000	0.980	0.020
D82 Immunodeficiency associated with other major defects	0.019	0.980	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.981	0.019
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.981	0.019
D80 Immunodeficiency with predominantly antibody defects	0.019	0.981	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.981	0.019
T42.2 Succinimides and oxazolidinediones	0.000	0.981	0.019
T41.5 Therapeutic gases	0.000	0.981	0.019
T41.4 Anaesthetic, unspecified	0.000	0.981	0.019
T41.3 Local anaesthetics	0.000	0.981	0.019
T41.1 Intravenous anaesthetics	0.000	0.981	0.019
T41.0 Inhaled anaesthetics	0.000	0.981	0.019
D84 Other immunodeficiencies	0.018	0.981	0.000
D83 Common variable immunodeficiency	0.018	0.982	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.982	0.017
D81 Combined immunodeficiencies	0.017	0.983	0.000
T42.0 Hydantoin derivatives	0.000	0.983	0.017
T41.2 Other and unspecified general anaesthetics	0.000	0.983	0.017
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.016	0.984	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.984	0.016
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.016	0.984	0.000
T38.0 Glucocorticoids and synthetic analogues	0.000	0.984	0.015
D82.1 Di George's syndrome	0.015	0.985	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.985	0.015
T38.7 Androgens and anabolic congeners	0.000	0.985	0.015
T38.5 Other oestrogens and progestogens	0.000	0.985	0.015
T38.4 Oral contraceptives	0.000	0.985	0.015
T38.2 Antithyroid drugs	0.000	0.985	0.015
D84.9 Immunodeficiency, unspecified	0.015	0.985	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.015	0.985	0.000
D83.9 Common variable immunodeficiency, unspecified	0.014	0.985	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.986	0.014
D82.9 Immunodeficiency associated with major defect, unspecified	0.014	0.986	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.014	0.986	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.014	0.986	0.000
D82.2 Immunodeficiency with short-limbed stature	0.014	0.986	0.000
D82.0 Wiskott-Aldrich syndrome	0.014	0.986	0.000
T88.4 Failed or difficult intubation	0.000	0.986	0.014
T45.2 Vitamins, not elsewhere classified	0.000	0.986	0.014
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.986	0.014
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.986	0.014
T45.8 Other primarily systemic and haematological agents	0.000	0.986	0.014
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.986	0.014
T45.6 Fibrinolysis-affecting drugs	0.000	0.986	0.014
T45.4 Iron and its compounds	0.000	0.986	0.014
T45.3 Enzymes, not elsewhere classified	0.000	0.986	0.014
D80.8 Other immunodeficiencies with predominantly antibody defects	0.014	0.986	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.014	0.986	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.014	0.986	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.014	0.986	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.014	0.986	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.986	0.014
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.014	0.986	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.986	0.014
D84.8 Other specified immunodeficiencies	0.014	0.986	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.014	0.986	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.013	0.986	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.013	0.986	0.000
D83.8 Other common variable immunodeficiencies	0.013	0.987	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.013	0.987	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.013	0.987	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.013	0.987	0.000
D84.1 Defects in the complement system	0.013	0.987	0.000
T45.0 Antiallergic and antiemetic drugs	0.000	0.987	0.013
D81.9 Combined immunodeficiency, unspecified	0.012	0.987	0.000
D81.8 Other combined immunodeficiencies	0.012	0.987	0.000
D81.7 Major histocompatibility complex class II deficiency	0.012	0.987	0.000
D81.6 Major histocompatibility complex class I deficiency	0.012	0.987	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.012	0.987	0.000
D81.4 Nezelof's syndrome	0.012	0.987	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.012	0.987	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.012	0.987	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.012	0.987	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.012	0.987	0.000
T45.5 Anticoagulants	0.000	0.987	0.012
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.012	0.988	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.988	0.012
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.988	0.012
S82.00 Fracture of patella (closed)	0.000	0.989	0.011
C44.1 Skin of eyelid, including canthus	0.000	0.990	0.010
S42.00 Fracture of clavicle (closed)	0.010	0.990	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.990	0.010
T39.4 Antirheumatics, not elsewhere classified	0.000	0.990	0.010
T39.2 Pyrazolone derivatives	0.000	0.990	0.010
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.010	0.990	0.000
D89.1 Cryoglobulinaemia	0.010	0.990	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.000	0.990	0.010
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.991	0.009
D89.3 Immune reconstitution syndrome	0.009	0.991	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.000	0.991	0.009
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.991	0.009
T42.4 Benzodiazepines	0.000	0.991	0.008
D89.0 Polyclonal hypergammaglobulinaemia	0.008	0.992	0.000
T88.9 Complication of surgical and medical care, unspecified	0.000	0.992	0.008
R72 Abnormality of white blood cells, not elsewhere classified	0.000	0.993	0.007
T88.5 Other complications of anaesthesia	0.000	0.993	0.007
T88.3 Malignant hyperthermia due to anaesthesis	0.000	0.993	0.007
T88.1 Other complications following immunisation, not elsewhere classified	0.000	0.993	0.007
T88.0 Infection following immunisation	0.000	0.993	0.007
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.993	0.007
D89.2 Hypergammaglobulinaemia, unspecified	0.007	0.993	0.000
S82.0 Fracture of patella	0.000	0.993	0.007
H44.2 Degenerative myopia	0.000	0.993	0.007
N48.6 Balanitis xerotica obliterans	0.000	0.993	0.007
T88.2 Shock due to anaesthesia	0.000	0.994	0.006
S82.01 Fracture of patella (open)	0.000	0.994	0.006
S12 Fracture of neck	0.006	0.994	0.000
O47.0 False labour before 37 completed weeks of gestation	0.006	0.994	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.006	0.994	0.000
S12.1 Fracture of second cervical vertebra	0.006	0.994	0.000
S12.2 Fracture of other specified cervical vertebra	0.006	0.994	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.006	0.994	0.000
T39.1 4-Aminophenol derivatives	0.000	0.994	0.006
S12.9 Fracture of neck, part unspecified	0.006	0.994	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.000	0.994	0.006
D89.9 Disorder involving the immune mechanism, unspecified	0.005	0.994	0.001
S12.90 Fracture of neck, part unspecified (closed)	0.006	0.994	0.000
K31.7 Polyp of stomach and duodenum	0.000	0.994	0.006
O47.9 False labour, unspecified	0.005	0.995	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.995	0.005
O47 False labour	0.005	0.995	0.000
H44 Disorders of globe	0.000	0.995	0.005
S12.0 Fracture of first cervical vertebra	0.005	0.995	0.000
C80.9 Malignant neoplasm, unspecified	0.005	0.995	0.000
S42.0 Fracture of clavicle	0.005	0.995	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.995	0.005
S12.7 Multiple fractures of cervical spine	0.005	0.995	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.000	0.995	0.005
O47.1 False labour at or after 37 completed weeks of gestation	0.005	0.995	0.000
S12.8 Fracture of other parts of neck	0.005	0.995	0.000
H44.8 Other disorders of globe	0.000	0.995	0.005
J35.0 Chronic tonsillitis	0.005	0.995	0.000
L29.0 Pruritus ani	0.005	0.995	0.000
H44.4 Hypotony of eye	0.000	0.995	0.005
S12.11 Fracture of second cervical vertebra (open)	0.004	0.995	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.004	0.995	0.000
S12.91 Fracture of neck, part unspecified (open)	0.004	0.995	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.996	0.004
S12.00 Fracture of first cervical vertebra (closed)	0.004	0.996	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.004	0.996	0.000
H44.0 Purulent endophthalmitis	0.000	0.996	0.004
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.004	0.996	0.000
E16.2 Hypoglycaemia, unspecified	0.004	0.996	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.004	0.996	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.996	0.004
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.996	0.004
H44.3 Other degenerative disorders of globe	0.000	0.996	0.004
S12.01 Fracture of first cervical vertebra (open)	0.004	0.996	0.000
X62.9 Unspecified place	0.000	0.996	0.004
H44.1 Other endophthalmitis	0.000	0.996	0.004
R73.0 Abnormal glucose tolerance test	0.000	0.996	0.004
R76.8 Other specified abnormal immunological findings in serum	0.000	0.996	0.004
S42.01 Fracture of clavicle (open)	0.004	0.996	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
S12.71 Multiple fractures of cervical spine (open)	0.004	0.996	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.004	0.996	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.996	0.004
E16.0 Drug-induced hypoglycaemia without coma	0.004	0.996	0.000
H44.5 Degenerated conditions of globe	0.000	0.996	0.004
S12.81 Fracture of other parts of neck (open)	0.003	0.996	0.000
S12.80 Fracture of other parts of neck (closed)	0.003	0.996	0.000
J35 Chronic diseases of tonsils and adenoids	0.004	0.996	0.000
Y43.4 Immunosuppressive agents	0.004	0.996	0.000
H44.9 Disorder of globe, unspecified	0.000	0.996	0.004
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.996	0.003
C18.7 Sigmoid colon	0.000	0.996	0.004
E16 Other disorders of pancreatic internal secretion	0.004	0.996	0.000
M22.4 Chondromalacia patellae	0.004	0.996	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.997	0.003
S10-S19 Injuries to the neck	0.003	0.997	0.000
R76 Other abnormal immunological findings in serum	0.000	0.997	0.003
S14.1 Other and unspecified injuries of cervical spinal cord	0.003	0.997	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
S14 Injury of nerves and spinal cord at neck level	0.003	0.997	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.003	0.997	0.000
T39.0 Salicylates	0.000	0.997	0.003
H60.9 Otitis externa, unspecified	0.003	0.997	0.000
F01.9 Vascular dementia, unspecified	0.003	0.997	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.000	0.997	0.003
J35.1 Hypertrophy of tonsils	0.003	0.997	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.997	0.003
M19.99 Arthrosis, unspecified (Site unspecified)	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.997	0.003
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.997	0.003
R73 Elevated blood glucose level	0.000	0.997	0.003
J35.2 Hypertrophy of adenoids	0.003	0.997	0.000
M77.1 Lateral epicondylitis	0.000	0.997	0.003
S11 Open wound of neck	0.003	0.997	0.000
D75.2 Essential thrombocytosis	0.000	0.997	0.003
E16.1 Other hypoglycaemia	0.003	0.997	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.003	0.997	0.000
S11.8 Open wound of other parts of neck	0.003	0.997	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.997	0.003
R63.4 Abnormal weight loss	0.000	0.997	0.003
E16.9 Disorder of pancreatic internal secretion, unspecified	0.003	0.997	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.003	0.997	0.000
E16.4 Abnormal secretion of gastrin	0.003	0.997	0.000
E16.3 Increased secretion of glucagon	0.003	0.997	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.003	0.997	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.000	0.997	0.003
Z12.8 Special screening examination for neoplasm of other sites	0.003	0.997	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.997	0.003
S52.10 Fracture of upper end of radius (closed)	0.003	0.997	0.000
S17 Crushing injury of neck	0.003	0.997	0.000
S15 Injury of blood vessels at neck level	0.003	0.997	0.000
S18 Traumatic amputation at neck level	0.003	0.997	0.000
S16 Injury of muscle and tendon at neck level	0.003	0.997	0.000
R76.2 False-positive serological test for syphilis	0.000	0.997	0.003
R76.1 Abnormal reaction to tuberculin test	0.000	0.997	0.003
F43.2 Adjustment disorders	0.000	0.997	0.003
R76.0 Raised antibody titer	0.000	0.997	0.003
S14.3 Injury of brachial plexus	0.003	0.997	0.000
S19 Other and unspecified injuries of neck	0.003	0.997	0.000
D48.6 Breast	0.003	0.997	0.000
S14.6 Injury of other and unspecified nerves of neck	0.003	0.997	0.000
S14.5 Injury of cervical sympathetic nerves	0.003	0.997	0.000
S14.4 Injury of peripheral nerves of neck	0.003	0.997	0.000
S14.2 Injury of nerve root of cervical spine	0.003	0.997	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.003	0.997	0.000
S11.7 Multiple open wounds of neck	0.003	0.997	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.997	0.003
G72.9 Myopathy, unspecified	0.000	0.997	0.003
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.997	0.003
D75.1 Secondary polycythaemia	0.000	0.997	0.003
R76.9 Abnormal immunological finding in serum, unspecified	0.000	0.997	0.002
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.000	0.997	0.002
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.002	0.997	0.000
M77.57 Other enthesopathy of foot-Ankle/Foot	0.000	0.998	0.002
D75.0 Familial erythrocytosis	0.000	0.998	0.002
G72.0 Drug-induced myopathy	0.000	0.998	0.002
Q07.0 Arnold-Chiari syndrome	0.000	0.998	0.002
R78 Findings of drugs and other substances, not normally found in blood	0.000	0.998	0.002
M77.19 Lateral epicondylitis (Site unspecified)	0.000	0.998	0.002
M77.18 Lateral epicondylitis-Other	0.000	0.998	0.002
M77.17 Lateral epicondylitis-Ankle/Foot	0.000	0.998	0.002
M77.16 Lateral epicondylitis (Lower leg)	0.000	0.998	0.002
M77.15 Lateral epicondylitis (Pelvic region and thigh)	0.000	0.998	0.002
M77.14 Lateral epicondylitis-Hand	0.000	0.998	0.002
M77.11 Lateral epicondylitis-Shldr region	0.000	0.998	0.002
M77.10 Lateral epicondylitis (Multiple sites)	0.000	0.998	0.002
K04.6 Periapical abscess with sinus	0.002	0.998	0.000
M70.6 Trochanteric bursitis	0.002	0.998	0.000
S11.2 Open wound involving pharynx and cervical oesophagus	0.002	0.998	0.000
S11.1 Open wound involving thyroid gland	0.002	0.998	0.000
S11.0 Open wound involving larynx and trachea	0.002	0.998	0.000
Z30.1 Insertion of (intra-uterine) contraceptive device	0.002	0.998	0.000
R70.1 Abnormal plasma viscosity	0.000	0.998	0.002
J32.0 Chronic maxillary sinusitis	0.000	0.998	0.002
R70.0 Elevated erythrocyte sedimentation rate	0.000	0.998	0.002
R71 Abnormality of red blood cells	0.000	0.998	0.002
S19.9 Unspecified injury of neck	0.002	0.998	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.002	0.998	0.000
R78.8 Finding of other specified substances, not normally found in blood	0.000	0.998	0.002
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.002	0.998	0.000
T31.0 Burns involving less than 10% of body surface	0.000	0.998	0.002
Z80.3 Family history of malignant neoplasm of breast	0.000	0.998	0.002
S15.9 Injury of unspecified blood vessel at neck level	0.002	0.998	0.000
S15.8 Injury of other blood vessels at neck level	0.002	0.998	0.000
S15.7 Injury of multiple blood vessels at neck level	0.002	0.998	0.000
S15.3 Injury of internal jugular vein	0.002	0.998	0.000
S15.2 Injury of external jugular vein	0.002	0.998	0.000
S15.1 Injury of vertebral artery	0.002	0.998	0.000
S15.0 Injury of carotid artery	0.002	0.998	0.000
S17.9 Crushing injury of neck, part unspecified	0.002	0.998	0.000
S17.8 Crushing injury of other parts of neck	0.002	0.998	0.000
S17.0 Crushing injury of larynx and traches	0.002	0.998	0.000
S19.7 Multiple injuries of neck	0.002	0.998	0.000
R74 Abnormal serum enzyme levels	0.000	0.998	0.002
S10 Superficial injury of neck	0.002	0.998	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.998	0.002
T43.2 Other and unspecified antidepressants	0.000	0.998	0.002
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.000	0.998	0.002
H60.8 Other otitis externa	0.002	0.998	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
M77.13 Lateral epicondylitis-Forearm	0.000	0.998	0.002
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.002	0.998	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.002	0.998	0.000
M70.69 Trochanteric bursitis-Site unspec	0.002	0.998	0.000
M77.5 Other enthesopathy of foot	0.000	0.998	0.002
G72 Other myopathies	0.000	0.998	0.002
S13.5 Sprain and strain of thyroid region	0.002	0.998	0.000
S13.3 Multiple dislocations of neck	0.002	0.998	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.002	0.998	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.002	0.998	0.000
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
H60 Otitis externa	0.002	0.998	0.000
R78.9 Finding of unspecified substance, not normally found in blood	0.000	0.998	0.002
R78.7 Finding of abnormal level of heavy metals in blood	0.000	0.998	0.002
R78.6 Finding of steroid agent in blood	0.000	0.998	0.002
R78.5 Finding of psychotropic drug in blood	0.000	0.998	0.002
R78.4 Finding of other drugs of addictive potential in blood	0.000	0.998	0.002
R78.3 Finding of hallucinogen in blood	0.000	0.998	0.002
R78.2 Finding of cocaine in blood	0.000	0.998	0.002
R78.1 Finding of opiate drug in blood	0.000	0.998	0.002
M70.68 Trochanteric bursitis-Other	0.002	0.998	0.000
M70.67 Trochanteric bursitis-Ankle/Foot	0.002	0.998	0.000
M70.66 Trochanteric bursitis-Lower Leg	0.002	0.998	0.000
M70.64 Trochanteric bursitis-Hand	0.002	0.998	0.000
M70.63 Trochanteric bursitis-Forearm	0.002	0.998	0.000
M70.62 Trochanteric bursitis-Upper arm	0.002	0.998	0.000
M70.61 Trochanteric bursitis-Shldr region	0.002	0.998	0.000
M70.60 Trochanteric bursitis-Mult sites	0.002	0.998	0.000
Q89.2 Congenital malformations of other endocrine glands	0.000	0.998	0.002
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.000	0.998	0.002
H60.3 Other infective otitis externa	0.002	0.998	0.000
A02.0 Salmonella gastro-enteritis	0.002	0.998	0.000
S19.8 Other specified injuries of neck	0.002	0.998	0.000
R77 Other abnormalities of plasma proteins	0.000	0.998	0.002
D35.1 Parathyroid gland	0.000	0.998	0.002
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.000	0.998	0.002
S13.1 Dislocation of cervical vertebra	0.002	0.998	0.000
Z49.1 Extracorporeal dialysis	0.002	0.998	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.000	0.998	0.002
O68 Labour and delivery complicated by foetal stress [distress]	0.002	0.998	0.000
S11.9 Open wound of neck, part unspecified	0.002	0.998	0.000
F43.1 Posttraumatic stress disorder	0.000	0.998	0.002
K91.1 Postgastric surgery syndromes	0.000	0.998	0.002
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.000	0.998	0.002
H43-H45 Disorders of vitreous body and globe	0.000	0.998	0.002
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.998	0.002
S10.1 Other and unspecified superficial injuries of throat	0.002	0.998	0.000
J94.8 Other specified pleural conditions	0.002	0.998	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.002	0.998	0.000
D48.5 Skin	0.002	0.998	0.000
L20.9 Atopic dermatitis, unspecified	0.002	0.998	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.002	0.998	0.000
S10.7 Multiple superficial injuries of neck	0.002	0.998	0.000
S10.0 Contusion of throat	0.002	0.998	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.998	0.002
H60.4 Cholesteatoma of external ear	0.002	0.998	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.998	0.002
R77.9 Abnormality of plasma protein, unspecified	0.001	0.998	0.001
S10.8 Superficial injury of other parts of neck	0.002	0.998	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.998	0.000
G61.8 Other inflammatory polyneuropathies	0.002	0.998	0.000
G72.3 Periodic paralysis	0.000	0.998	0.002
G72.2 Myopathy due to other toxic agents	0.000	0.998	0.002
F43 Reaction to severe stress, and adjustment disorders	0.000	0.998	0.002
M77.59 Other enthesopathy of foot-Site unspec	0.000	0.998	0.002
M77.58 Other enthesopathy of foot-Other	0.000	0.998	0.002
M77.56 Other enthesopathy of foot-Lower Leg	0.000	0.998	0.002
M77.55 Other enthesopathy of foot-Pelvic/Thigh	0.000	0.998	0.002
M77.54 Other enthesopathy of foot-Hand	0.000	0.998	0.002
M77.53 Other enthesopathy of foot-Forearm	0.000	0.998	0.002
M77.52 Other enthesopathy of foot-Upper arm	0.000	0.998	0.002
M77.51 Other enthesopathy of foot-Shldr region	0.000	0.998	0.002
M77.50 Other enthesopathy of foot-Mult sites	0.000	0.998	0.002
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.998	0.002
M77 Other enthesopathies	0.000	0.998	0.002
M21.24 Flexion deformity (Hand)	0.002	0.998	0.000
S52.01 Fracture of upper end of ulna (open)	0.002	0.998	0.000
L57.0 Actinic keratosis	0.000	0.998	0.002
S52.1 Fracture of upper end of radius	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations