TreeWAS – Variant ID: rs41527949

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000
M06 Other rheumatoid arthritis	0.999	0.001
M06.9 Rheumatoid arthritis, unspecified	0.999	0.001
M65-M68 Disorders of synovium and tendon	0.997	0.003
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.991	0.009
M20-M25 Other joint disorders	0.984	0.016
M65 Synovitis and tenosynovitis	0.984	0.016
M25 Other joint disorders, not elsewhere classified	0.981	0.019
M65.9 Synovitis and tenosynovitis, unspecified	0.968	0.032
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.960	0.040
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.959	0.041
M40-M43 Deforming dorsopathies	0.959	0.041
M50-M54 Other dorsopathies	0.957	0.043
T92 Sequelae of injuries of upper limb	0.949	0.051
M67 Other disorders of synovium and tendon	0.939	0.061
# Top node	0.938	0.062
I60-I69 Cerebrovascular diseases	0.936	0.064
M43 Other deforming dorsopathies	0.935	0.065
Chapter IX Diseases of the circulatory system	0.928	0.072
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.926	0.074
I67 Other cerebrovascular diseases	0.926	0.074
M54 Dorsalgia	0.926	0.074
M25.7 Osteophyte	0.925	0.075
S00-S09 Injuries to the head	0.924	0.076
M80-M85 Disorders of bone density and structure	0.919	0.081
I64 Stroke, not specified as haemorrhage or infarction	0.918	0.082
M25.77 Osteophyte (Ankle and foot)	0.910	0.090
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.910	0.090
I67.9 Cerebrovascular disease, unspecified	0.910	0.090
M34 Systemic sclerosis	0.908	0.092
M25.6 Stiffness of joint, not elsewhere classified	0.908	0.092
M21 Other acquired deformities of limbs	0.900	0.100
T92.0 Sequelae of open wound of upper limb	0.896	0.104
M43.1 Spondylolisthesis	0.892	0.108
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.890	0.110
M25.9 Joint disorder, unspecified	0.889	0.111
Chapter XX External causes of morbidity and mortality	0.887	0.113
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.886	0.114
T93 Sequelae of injuries of lower limb	0.886	0.114
M67.8 Other specified disorders of synovium and tendon	0.885	0.115
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.878	0.122
M54.5 Low back pain	0.877	0.123
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.876	0.124
M07 Psoriatic and enteropathic arthropathies	0.876	0.124
S00 Superficial injury of head	0.871	0.129
S60-S69 Injuries to the wrist and hand	0.869	0.131
Y86 Sequelae of other accidents	0.869	0.131
T20-T25 Burns and corrosions of external body surface, specified by site	0.868	0.132
M25.4 Effusion of joint	0.868	0.132
S20-S29 Injuries to the thorax	0.867	0.133
M43.16 Spondylolisthesis (Lumbar region)	0.863	0.137
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.860	0.140
M86-M90 Other osteopathies	0.858	0.142
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.853	0.147
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.849	0.151
M50 Cervical disk disorders	0.848	0.152
I70-I79 Diseases of arteries, arterioles and capillaries	0.848	0.152
M21.3 Wrist or foot drop (acquired)	0.848	0.152
M54.59 Low back pain (Site unspecified)	0.844	0.156
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.844	0.156
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.837	0.163
M54.9 Dorsalgia, unspecified	0.836	0.164
M06.4 Inflammatory polyarthropathy	0.836	0.164
S00.8 Superficial injury of other parts of head	0.832	0.168
M43.0 Spondylolysis	0.831	0.169
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.830	0.170
M25.5 Pain in joint	0.829	0.171
S02 Fracture of skull and facial bones	0.828	0.172
T84.1 Mechanical complication of internal fixation device of bones of limb	0.825	0.175
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.821	0.179
M05 Seropositive rheumatoid arthritis	0.818	0.182
S62 Fracture at wrist and hand level	0.818	0.182
M25.78 Osteophyte (Other)	0.817	0.183
T91 Sequelae of injuries of neck and trunk	0.817	0.183
S09 Other and unspecified injuries of head	0.814	0.186
Chapter I Certain infectious and parasitic diseases	0.812	0.188
M34.9 Systemic sclerosis, unspecified	0.811	0.189
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.810	0.190
M11 Other crystal arthropathies	0.809	0.191
I67.8 Other specified cerebrovascular diseases	0.808	0.192
M66 Spontaneous rupture of synovium and tendon	0.807	0.193
I71 Aortic aneurysm and dissection	0.805	0.195
I63 Cerebral infarction	0.803	0.197
M06.0 Seronegative rheumatoid arthritis	0.801	0.199
I67.1 Cerebral aneurysm, nonruptured	0.801	0.199
M60-M63 Disorders of muscles	0.798	0.202
I77 Other disorders of arteries and arterioles	0.796	0.204
B15-B19 Viral hepatitis	0.792	0.208
M65.3 Trigger finger	0.789	0.211
M07.3 Other psoriatic arthropathies	0.787	0.213
I69 Sequelae of cerebrovascular disease	0.787	0.213
M14 Arthropathies in other diseases classified elsewhere	0.787	0.213
S80-S89 Injuries to the knee and lower leg	0.787	0.213
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.785	0.215
S64 Injury of nerves at wrist and hand level	0.783	0.217
M25.59 Pain in joint (Site unspecified)	0.781	0.219
S02.0 Fracture of vault of skull	0.777	0.223
M67.2 Synovial hypertrophy, not elsewhere classified	0.774	0.226
M50.0 Cervical disk disorder with myelopathy	0.774	0.226
M50.3 Other cervical disk degeneration	0.773	0.227
M54.3 Sciatica	0.772	0.228
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.768	0.232
I77.1 Stricture of artery	0.766	0.234
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.766	0.234
T84.3 Mechanical complication of other bone devices, implants and grafts	0.766	0.234
M43.02 Spondylolysis (Cervical region)	0.761	0.239
T80 Complications following infusion, transfusion and therapeutic injection	0.757	0.243
M80 Osteoporosis with pathological fracture	0.757	0.243
M25.71 Osteophyte (Shoulder region)	0.757	0.243
T93.1 Sequelae of fracture of femur	0.757	0.243
S81 Open wound of lower leg	0.757	0.243
S09.9 Unspecified injury of head	0.755	0.245
T23 Burn and corrosion of wrist and hand	0.751	0.249
M85 Other disorders of bone density and structure	0.749	0.251
S05 Injury of eye and orbit	0.749	0.251
T92.8 Sequelae of other specified injuries of upper limb	0.749	0.251
M54.4 Lumbago with sciatica	0.748	0.252
S81.8 Open wound of other parts of lower leg	0.746	0.254
M25.96 Joint disorder, unspecified (Lower leg)	0.746	0.254
V01-V09 Pedestrian injured in transport accident	0.743	0.256
S02.00 Fracture of vault of skull (closed)	0.740	0.260
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.740	0.260
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.739	0.261
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.738	0.262
M81 Osteoporosis without pathological fracture	0.736	0.264
T00-T07 Injuries involving multiple body regions	0.735	0.265
M25.51 Pain in joint (Shoulder region)	0.734	0.266
M84 Disorders of continuity of bone	0.733	0.267
I62 Other nontraumatic intracranial haemorrhage	0.732	0.268
V40-V49 Car occupant injured in transport accident	0.732	0.268
M65.4 Radial styloid tenosynovitis [de Quervain]	0.732	0.268
M30 Polyarteritis nodosa and related conditions	0.731	0.269
S00.4 Superficial injury of ear	0.731	0.269
T90 Sequelae of injuries of head	0.731	0.269
Chapter XXII Codes for special purposes	0.729	0.271
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.727	0.272
M34.8 Other forms of systemic sclerosis	0.727	0.273
B18 Chronic viral hepatitis	0.726	0.274
S62.6 Fracture of other finger	0.726	0.274
Q38-Q45 Other congenital malformations of the digestive system	0.724	0.276
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.723	0.277
M89 Other disorders of bone	0.723	0.277
S27 Injury of other and unspecified intrathoracic organs	0.722	0.278
A15-A19 Tuberculosis	0.722	0.278
Chapter V Mental and behavioural disorders	0.722	0.278
S64.4 Injury of digital nerve of other finger	0.722	0.278
T92.2 Sequelae of fracture at wrist and hand level	0.721	0.279
S90-S99 Injuries to the ankle and foot	0.719	0.281
M25.46 Effusion of joint (Lower leg)	0.718	0.282
Chapter X Diseases of the respiratory system	0.717	0.283
M12 Other specific arthropathies	0.717	0.283
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283
M08 Juvenile arthritis	0.717	0.283
M06.8 Other specified rheumatoid arthritis	0.717	0.283
M06.2 Rheumatoid bursitis	0.717	0.283
M06.1 Adult-onset Still's disease	0.717	0.283
M06.98 Rheumatoid arthritis, unspecified (Other)	0.716	0.284
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.715	0.285
I63.9 Cerebral infarction, unspecified	0.714	0.286
M65.8 Other synovitis and tenosynovitis	0.713	0.286
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.713	0.287
M87 Osteonecrosis	0.712	0.288
T92.1 Sequelae of fracture of arm	0.711	0.289
T92.9 Sequelae of unspecified injury of upper limb	0.710	0.290
M25.44 Effusion of joint (Hand)	0.710	0.290
M21.7 Unequal limb length (acquired)	0.709	0.291
S21 Open wound of thorax	0.709	0.291
S62.7 Multiple fractures of fingers	0.709	0.291
M33 Dermatopolymyositis	0.709	0.291
M43.12 Spondylolisthesis (Cervical region)	0.708	0.292
B17 Other acute viral hepatitis	0.707	0.293
T15-T19 Effects of foreign body entering through natural orifice	0.706	0.294
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.705	0.295
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.705	0.295
M65.2 Calcific tendinitis	0.705	0.295
M65.1 Other infective (teno)synovitis	0.705	0.295
M65.0 Abscess of tendon sheath	0.705	0.295
M34.1 CR(E)ST syndrome	0.705	0.295
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.704	0.296
M25.2 Flail joint	0.704	0.296
M25.1 Fistula of joint	0.704	0.296
S60 Superficial injury of wrist and hand	0.704	0.296
M06.3 Rheumatoid nodule	0.702	0.298
S22 Fracture of rib(s), sternum and thoracic spine	0.699	0.301
T91.3 Sequelae of injury of spinal cord	0.699	0.301
M21.2 Flexion deformity	0.699	0.301
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.697	0.302
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.697	0.303
M25.97 Joint disorder, unspecified (Ankle and foot)	0.697	0.303
W50-W64 Exposure to animate mechanical forces	0.697	0.303
M25.47 Effusion of joint (Ankle and foot)	0.695	0.305
M53 Other dorsopathies, not elsewhere classified	0.695	0.305
M25.94 Joint disorder, unspecified (Hand)	0.694	0.306
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.694	0.306
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.694	0.306
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.694	0.306
V10-V19 Pedal cyclist injured in transport accident	0.694	0.306
Q80-Q89 Other congenital malformations	0.694	0.306
S70-S79 Injuries to the hip and thigh	0.694	0.306
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.693	0.307
S62.61 Fracture of other finger (open)	0.692	0.308
M25.55 Pain in joint (Pelvic region and thigh)	0.691	0.309
M25.91 Joint disorder, unspecified (Shoulder region)	0.690	0.310
M54.57 Low back pain (Lumbosacral region)	0.690	0.310
T33-T35 Frostbite	0.689	0.311
T26-T28 Burns and corrosions confined to eye and internal organs	0.689	0.311
M05.9 Seropositive rheumatoid arthritis, unspecified	0.689	0.311
T95 Sequelae of burns, corrosions and frostbite	0.688	0.312
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.688	0.312
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.688	0.312
B18.2 Chronic viral hepatitis C	0.688	0.312
M42 Spinal osteochondrosis	0.687	0.313
M32 Systemic lupus erythematosus	0.687	0.313
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.687	0.313
J80-J84 Other respiratory diseases principally affecting the interstitium	0.687	0.313
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.686	0.314
T93.0 Sequelae of open wound of lower limb	0.686	0.314
T93.9 Sequelae of unspecified injury of lower limb	0.685	0.315
M00-M03 Infectious arthropathies	0.684	0.315
S62.8 Fracture of other and unspecified parts of wrist and hand	0.683	0.317
T91.9 Sequelae of unspecified injury of neck and trunk	0.681	0.318
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.680	0.319
T92.4 Sequelae of injury of nerve of upper limb	0.680	0.319
T98 Sequelae of other and unspecified effects of external causes	0.680	0.319
B90-B94 Sequelae of infectious and parasitic diseases	0.680	0.320
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.680	0.320
M54.8 Other dorsalgia	0.679	0.321
I67.0 Dissection of cerebral arteries, nonruptured	0.679	0.321
M80.5 Idiopathic osteoporosis with pathological fracture	0.679	0.321
I61 Intracerebral haemorrhage	0.676	0.324
T93.2 Sequelae of other fractures of lower limb	0.675	0.324
T79-T79 Certain early complications of trauma	0.674	0.326
M21.4 Flat foot [pes planus] (acquired)	0.674	0.326
M67.9 Disorder of synovium and tendon, unspecified	0.673	0.327
M67.4 Ganglion	0.673	0.327
M67.3 Transient synovitis	0.673	0.327
M67.0 Short Achilles tendon (acquired)	0.673	0.327
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.673	0.327
Chapter XVI Certain conditions originating in the perinatal period	0.673	0.327
T93.8 Sequelae of other specified injuries of lower limb	0.672	0.328
S62.1 Fracture of other carpal bone(s)	0.672	0.328
M11.2 Other chondrocalcinosis	0.672	0.328
I68 Cerebrovascular disorders in diseases classified elsewhere	0.671	0.329
M66.2 Spontaneous rupture of extensor tendons	0.671	0.329
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.671	0.329
M40 Kyphosis and lordosis	0.671	0.329
M43.9 Deforming dorsopathy, unspecified	0.670	0.329
M43.8 Other specified deforming dorsopathies	0.670	0.329
M43.6 Torticollis	0.670	0.329
M43.5 Other recurrent vertebral subluxation	0.670	0.329
M43.4 Other recurrent atlantoaxial subluxation	0.670	0.329
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.670	0.329
M43.2 Other fusion of spine	0.670	0.329
S20 Superficial injury of thorax	0.670	0.330
Y89 Sequelae of other external causes	0.670	0.330
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.668	0.331
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.668	0.332
M91-M94 Chondropathies	0.667	0.333
B35-B49 Mycoses	0.666	0.334
V20-V29 Motorcycle rider injured in transport accident	0.666	0.334
I00-I02 Acute rheumatic fever	0.665	0.335
F00-F09 Organic, including symptomatic, mental disorders	0.664	0.336
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.664	0.336
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.664	0.336
T94 Sequelae of injuries involving multiple and unspecified body regions	0.664	0.336
I67.7 Cerebral arteritis, not elsewhere classified	0.664	0.336
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.664	0.336
I67.5 Moyamoya disease	0.664	0.336
I67.4 Hypertensive encephalopathy	0.664	0.336
I67.3 Progressive vascular leukoencephalopathy	0.664	0.336
M54.0 Panniculitis affecting regions of neck and back	0.664	0.336
M25.79 Osteophyte (Site unspecified)	0.663	0.337
M25.73 Osteophyte (Forearm)	0.663	0.337
M25.70 Osteophyte (Multiple sites)	0.663	0.337
M81.4 Drug-induced osteoporosis	0.663	0.337
S08 Traumatic amputation of part of head	0.662	0.338
S07 Crushing injury of head	0.662	0.338
S04 Injury of cranial nerves	0.662	0.338
S03 Dislocation, sprain and strain of joints and ligaments of head	0.662	0.338
M25.0 Haemarthrosis	0.660	0.339
X58-X59 Accidental exposure to other and unspecified factors	0.660	0.339
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.660	0.340
M25.52 Pain in joint (Upper arm)	0.660	0.340
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.660	0.340
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.660	0.340
M21.1 Varus deformity, not elsewhere classified	0.660	0.340
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.659	0.341
M83 Adult osteomalacia	0.659	0.341
S65 Injury of blood vessels at wrist and hand level	0.657	0.343
Y00-Y09 Assault	0.656	0.343
I69.3 Sequelae of cerebral infarction	0.655	0.345
I95-I99 Other and unspecified disorders of the circulatory system	0.655	0.345
M54.92 Dorsalgia, unspecified (Cervical region)	0.653	0.347
B16 Acute hepatitis B	0.652	0.348
M25.8 Other specified joint disorders	0.652	0.348
M54.36 Sciatica (Lumbar region)	0.651	0.349
M34.2 Systemic sclerosis induced by drugs and chemicals	0.651	0.349
M34.0 Progressive systemic sclerosis	0.651	0.349
S02.4 Fracture of malar and maxillary bones	0.651	0.349
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.651	0.349
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.651	0.349
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.651	0.349
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.651	0.349
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.651	0.349
S00.9 Superficial injury of head, part unspecified	0.650	0.350
M65.34 Trigger finger-Hand	0.650	0.350
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.649	0.351
Q50-Q56 Congenital malformations of genital organs	0.649	0.351
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.648	0.351
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.648	0.352
B17.1 Acute hepatitis C	0.646	0.354
M21.9 Acquired deformity of limb, unspecified	0.645	0.355
M21.8 Other specified acquired deformities of limbs	0.645	0.355
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.644	0.355
Q00-Q07 Congenital malformations of the nervous system	0.644	0.355
X50-X57 Overexertion, travel and privation	0.644	0.356
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.644	0.356
S63.5 Sprain and strain of wrist	0.643	0.357
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.643	0.357
S02.5 Fracture of tooth	0.642	0.358
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.642	0.358
T90.5 Sequelae of intracranial injury	0.641	0.359
M41 Scoliosis	0.641	0.359
M54.99 Dorsalgia, unspecified (Site unspecified)	0.640	0.360
S64.1 Injury of median nerve at wrist and hand level	0.640	0.360
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.640	0.360
M43.15 Spondylolisthesis (Thoracolumbar region)	0.640	0.360
M43.14 Spondylolisthesis (Thoracic region)	0.640	0.360
M43.13 Spondylolisthesis (Cervicothoracic region)	0.640	0.360
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.640	0.360
M43.10 Spondylolisthesis (Multiple sites in spine)	0.640	0.360
M07.34 Other psoriatic arthropathies (Hand)	0.639	0.361
T20 Burn and corrosion of head and neck	0.637	0.363
M25.99 Joint disorder, unspecified (Site unspecified)	0.637	0.363
M25.98 Joint disorder, unspecified (Other)	0.637	0.363
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.637	0.363
M25.93 Joint disorder, unspecified (Forearm)	0.637	0.363
M25.92 Joint disorder, unspecified (Upper arm)	0.637	0.363
M25.90 Joint disorder, unspecified (Multiple sites)	0.637	0.363
T85 Complications of other internal prosthetic devices, implants and grafts	0.637	0.363
S05.8 Other injuries of eye and orbit	0.636	0.364
M54.39 Sciatica (Site unspecified)	0.636	0.364
Y35-Y36 Legal intervention and operations of war	0.636	0.364
Y10-Y34 Event of undetermined intent	0.636	0.364
X85-X99 Assault	0.636	0.364
X60-X84 Intentional self-harm	0.636	0.364
X30-X39 Exposure to forces of nature	0.636	0.364
X10-X19 Contact with heat and hot substances	0.636	0.364
X00-X09 Exposure to smoke, fire and flames	0.636	0.364
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.636	0.364
W75-W84 Other accidental threats to breathing	0.636	0.364
W65-W74 Accidental drowning and submersion	0.636	0.364
V98-V99 Other and unspecified transport accidents	0.636	0.364
V95-V97 Air and space transport accidents	0.636	0.364
V90-V94 Water transport accidents	0.636	0.364
V70-V79 Bus occupant injured in transport accident	0.636	0.364
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.636	0.364
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.636	0.364
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.636	0.364
J80 Adult respiratory distress syndrome	0.636	0.364
I74 Arterial embolism and thrombosis	0.636	0.364
M85.8 Other specified disorders of bone density and structure	0.636	0.364
M54.47 Lumbago with sciatica (Lumbosacral region)	0.636	0.364
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.635	0.365
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.635	0.365
T93.4 Sequelae of injury of nerve of lower limb	0.635	0.365
M14.6 Neuropathic arthropathy	0.634	0.366
T86 Failure and rejection of transplanted organs and tissues	0.634	0.366
M25.3 Other instability of joint	0.632	0.368
S00.0 Superficial injury of scalp	0.632	0.368
J84 Other interstitial pulmonary diseases	0.631	0.369
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.631	0.369
T23.3 Burn of third degree of wrist and hand	0.631	0.369
M82 Osteoporosis in diseases classified elsewhere	0.630	0.370
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.630	0.370
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.629	0.371
B50-B64 Protozoal diseases	0.629	0.371
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.629	0.371
M54.54 Low back pain-Thoracic	0.629	0.371
M54.53 Low back pain-Cervicothoracic	0.629	0.371
M54.52 Low back pain-Cervical	0.629	0.371
M54.51 Low back pain-Occipit-atl-axl	0.629	0.371
M07.6 Other enteropathic arthropathies	0.628	0.372
M07.5 Arthropathy in ulcerative colitis	0.628	0.372
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.628	0.372
M07.2 Psoriatic spondylitis	0.628	0.372
M07.1 Arthritis mutilans	0.628	0.372
M07.0 Distal interphalangeal psoriatic arthropathy	0.628	0.372
T80.2 Infections following infusion, transfusion and therapeutic injection	0.626	0.374
M86 Osteomyelitis	0.626	0.374
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.626	0.374
M62 Other disorders of muscle	0.625	0.374
M88 Paget's disease of bone [osteitis deformans]	0.625	0.375
T66-T78 Other and unspecified effects of external causes	0.624	0.376
W20-W49 Exposure to inanimate mechanical forces	0.624	0.376
M07.39 Other psoriatic arthropathies (Site unspecified)	0.623	0.377
T25 Burn and corrosion of ankle and foot	0.622	0.378
T21 Burn and corrosion of trunk	0.622	0.378
M25.49 Effusion of joint (Site unspecified)	0.622	0.378
M25.48 Effusion of joint (Other)	0.622	0.378
M25.43 Effusion of joint (Forearm)	0.622	0.378
M25.42 Effusion of joint (Upper arm)	0.622	0.378
M25.41 Effusion of joint (Shoulder region)	0.622	0.378
M25.40 Effusion of joint (Multiple sites)	0.622	0.378
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.622	0.378
S26 Injury of heart	0.622	0.378
S25 Injury of blood vessels of thorax	0.622	0.378
S24 Injury of nerves and spinal cord at thorax level	0.622	0.378
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.622	0.378
I77.6 Arteritis, unspecified	0.620	0.380
M07.30 Other psoriatic arthropathies (Multiple sites)	0.619	0.381
W00-W19 Falls	0.619	0.381
S64.0 Injury of ulnar nerve at wrist and hand level	0.618	0.382
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.617	0.383
Q35-Q37 Cleft lip and cleft palate	0.617	0.383
Q30-Q34 Congenital malformations of the respiratory system	0.617	0.383
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.616	0.384
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.616	0.384
X20-X29 Contact with venomous animals and plants	0.614	0.386
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.613	0.387
M54.96 Dorsalgia, unspecified (Lumbar region)	0.613	0.387
T23.2 Burn of second degree of wrist and hand	0.611	0.389
S91 Open wound of ankle and foot	0.611	0.389
V43 Car occupant injured in collision with car, pick-up truck or van	0.611	0.389
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.610	0.390
S00.2 Other superficial injuries of eyelid and periocular area	0.610	0.390
M60 Myositis	0.610	0.390
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.608	0.392
M50.9 Cervical disk disorder, unspecified	0.608	0.392
M50.8 Other cervical disk disorders	0.608	0.392
M87.2 Osteonecrosis due to previous trauma	0.608	0.392
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.608	0.392
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.608	0.392
J00-J06 Acute upper respiratory infections	0.608	0.392
M21.39 Wrist or foot drop (acquired)-Site unspec	0.608	0.392
M21.38 Wrist or foot drop (acquired)-Other	0.608	0.392
M21.36 Wrist or foot drop (acquired)-Lower leg	0.608	0.392
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.608	0.392
M21.34 Wrist or foot drop (acquired) (Hand)	0.608	0.392
M21.33 Wrist or foot drop (acquired) (Forearm)	0.608	0.392
M21.32 Wrist or foot drop (acquired)-Upper arm	0.608	0.392
M21.31 Wrist or foot drop (acquired)-Shldr region	0.608	0.392
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.608	0.392
S62.70 Multiple fractures of fingers (closed)	0.608	0.392
M67.1 Other contracture of tendon (sheath)	0.607	0.392
S02.7 Multiple fractures involving skull and facial bones	0.607	0.393
B65-B83 Helminthiases	0.607	0.393
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.607	0.393
I63.8 Other cerebral infarction	0.606	0.394
Q38 Other congenital malformations of tongue, mouth and pharynx	0.605	0.395
M25.58 Pain in joint (Other)	0.605	0.395
M24 Other specific joint derangements	0.605	0.395
M21.6 Other acquired deformities of ankle and foot	0.605	0.395
I77.0 Arteriovenous fistula, acquired	0.604	0.395
F05 Delirium, not induced by alcohol and other psychoactive substances	0.604	0.396
I30-I52 Other forms of heart disease	0.604	0.396
M43.19 Spondylolisthesis (Site unspecified)	0.603	0.397
M84.1 Nonunion of fracture [pseudarthrosis]	0.603	0.397
Y88 Sequelae of surgical and medical care as external cause	0.603	0.397
S82 Fracture of lower leg, including ankle	0.603	0.397
T91.1 Sequelae of fracture of spine	0.602	0.398
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.601	0.398
M25.72 Osteophyte (Upper arm)	0.601	0.399
V02 Pedestrian injured in collision with two- or three-wheeled motor vehicle	0.601	0.399
M81.40 Drug-induced osteoporosis (Multiple sites)	0.601	0.399
I47 Paroxysmal tachycardia	0.600	0.400
M54.94 Dorsalgia, unspecified (Thoracic region)	0.599	0.400
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.599	0.400
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.599	0.400
M06.48 Inflammatory polyarthropathy (Other)	0.599	0.401
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.599	0.401
M06.46 Inflammatory polyarthropathy (Lower leg)	0.599	0.401
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.599	0.401
M06.44 Inflammatory polyarthropathy (Hand)	0.599	0.401
M06.43 Inflammatory polyarthropathy (Forearm)	0.599	0.401
M06.42 Inflammatory polyarthropathy (Upper arm)	0.599	0.401
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.599	0.401
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.599	0.401
S22.3 Fracture of rib	0.598	0.402
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.598	0.402
I47.1 Supraventricular tachycardia	0.597	0.403
S10-S19 Injuries to the neck	0.596	0.404
M43.09 Spondylolysis (Site unspecified)	0.596	0.404
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.596	0.404
M43.07 Spondylolysis (Lumbosacral region)	0.596	0.404
M43.05 Spondylolysis (Thoracolumbar region)	0.596	0.404
M43.04 Spondylolysis (Thoracic region)	0.596	0.404
M43.03 Spondylolysis (Cervicothoracic region)	0.596	0.404
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.596	0.404
M43.00 Spondylolysis (Multiple sites in spine)	0.596	0.404
I70 Atherosclerosis	0.594	0.406
S00.3 Superficial injury of nose	0.594	0.406
S02.8 Fractures of other skull and facial bones	0.594	0.406
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.593	0.407
J95-J99 Other diseases of the respiratory system	0.593	0.407
S00.7 Multiple superficial injuries of head	0.593	0.407
V09 Pedestrian injured in other and unspecified transport accidents	0.591	0.408
J06 Acute upper respiratory infections of multiple and unspecified sites	0.591	0.409
M45-M49 Spondylopathies	0.591	0.409

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations