TreeWAS – Variant ID: rs4246949

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C80 Malignant neoplasm without specification of site	0.000	0.706	0.294
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.709	0.291
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.716	0.284
C80.9 Malignant neoplasm, unspecified	0.000	0.716	0.284
C79 Secondary malignant neoplasm of other sites	0.000	0.718	0.282
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.722	0.278
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.725	0.275
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.735	0.265
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.736	0.264
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.742	0.258
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.758	0.242
C78.2 Secondary malignant neoplasm of pleura	0.000	0.768	0.232
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.773	0.227
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.786	0.214
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.790	0.209
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.796	0.204
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.802	0.198
C79.6 Secondary malignant neoplasm of ovary	0.000	0.803	0.197
C79.2 Secondary malignant neoplasm of skin	0.000	0.812	0.188
C78.0 Secondary malignant neoplasm of lung	0.000	0.814	0.186
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.825	0.175
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.175	0.825	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.861	0.139
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.872	0.127
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.879	0.121
C77.1 Intrathoracic lymph nodes	0.000	0.882	0.118
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.887	0.113
C77.9 Lymph node, unspecified	0.000	0.897	0.103
C76.1 Thorax	0.000	0.905	0.095
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.908	0.091
C76.7 Other ill-defined sites	0.000	0.908	0.091
C76.5 Lower limb	0.000	0.908	0.091
C76.4 Upper limb	0.000	0.908	0.091
C77.5 Intrapelvic lymph nodes	0.000	0.913	0.087
C77.4 Inguinal and lower limb lymph nodes	0.000	0.919	0.081
C77.8 Lymph nodes of multiple regions	0.000	0.921	0.079
C76.2 Abdomen	0.001	0.921	0.078
C76.0 Head, face and neck	0.001	0.923	0.077
C76.3 Pelvis	0.001	0.937	0.062
C78.7 Secondary malignant neoplasm of liver	0.000	0.943	0.057
C81 Hodgkin's disease	0.000	0.945	0.055
C81.9 Hodgkin's disease, unspecified	0.000	0.947	0.053
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.947	0.053
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.948	0.052
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.948	0.052
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.949	0.051
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.951	0.049
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.951	0.049
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.952	0.048
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.952	0.048
C81.1 Nodular sclerosis	0.000	0.953	0.047
C81.7 Other Hodgkin's disease	0.000	0.953	0.047
C93 Monocytic leukaemia	0.000	0.956	0.044
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.956	0.044
C92 Myeloid leukaemia	0.000	0.956	0.043
C82.3 Follicular lymphoma grade IIIa	0.000	0.958	0.042
C81.2 Mixed cellularity	0.000	0.958	0.042
C82.0 Small cleaved cell, follicular	0.000	0.958	0.042
C92.0 Acute myeloid leukaemia	0.000	0.959	0.041
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.960	0.040
C81.3 Lymphocytic depletion	0.000	0.960	0.040
C84.8 Cutaneous T-cell lymphoma, unspecified	0.000	0.961	0.039
C84.4 Peripheral T-cell lymphoma	0.000	0.961	0.039
C88 Malignant immunoproliferative diseases	0.000	0.961	0.039
C81.0 Lymphocytic predominance	0.000	0.961	0.039
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.962	0.038
C93.1 Chronic monocytic leukaemia	0.000	0.962	0.038
C94 Other leukaemias of specified cell type	0.000	0.962	0.038
C84.0 Mycosis fungoides	0.000	0.962	0.038
C82.6 Cutaneous follicle centre lymphoma	0.000	0.963	0.037
C82.5 Diffuse follicle centre lymphoma	0.000	0.963	0.037
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.963	0.037
C82.4 Follicular lymphoma grade IIIb	0.000	0.964	0.036
C85.0 Lymphosarcoma	0.000	0.964	0.036
C82.2 Large cell, follicular	0.000	0.964	0.036
C86 Other specified types of T/NK-cell lymphoma	0.000	0.964	0.035
C95 Leukaemia of unspecified cell type	0.000	0.965	0.035
C84.5 Other and unspecified T-cell lymphomas	0.000	0.965	0.035
C84.9 Mature T/NK-cell lymphoma, unspecified	0.000	0.966	0.034
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.000	0.966	0.034
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.000	0.966	0.034
C84.3 Lymphoepithelioid lymphoma	0.000	0.966	0.034
C84.2 T-zone lymphoma	0.000	0.966	0.034
C84.1 Sezary's diease	0.000	0.966	0.034
C92.7 Other myeloid leukaemia	0.000	0.966	0.034
C92.5 Acute myelomonocytic leukaemia	0.000	0.967	0.033
C93.9 Monocytic leukaemia, unspecified	0.000	0.968	0.032
C93.7 Other monocytic leukaemia	0.000	0.968	0.032
C93.3 Juvenile myelomonocytic leukaemia	0.000	0.968	0.032
C93.2 Subacute monocytic leukaemia	0.000	0.968	0.032
C93.0 Acute monocytic leukaemia	0.000	0.968	0.032
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.969	0.031
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.969	0.031
C92.3 Myeloid sarcoma	0.000	0.969	0.031
C92.9 Myeloid leukaemia, unspecified	0.000	0.969	0.031
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.969	0.031
I80 Phlebitis and thrombophlebitis	0.030	0.970	0.000
C92.2 Subacute myeloid leukaemia	0.000	0.970	0.030
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.971	0.029
C92.4 Acute promyelocytic leukaemia	0.000	0.971	0.029
C88.9 Malignant immunoproliferative disease, unspecified	0.000	0.972	0.028
C88.7 Other malignant immunoproliferative diseases	0.000	0.972	0.028
C88.3 Immunoproliferative small intestinal disease	0.000	0.972	0.028
C88.2 Gamma heavy chain disease	0.000	0.972	0.028
C88.1 Alpha heavy chain disease	0.000	0.972	0.028
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.972	0.028
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.972	0.027
C96.8 Histiocytic sarcoma	0.000	0.972	0.027
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.972	0.027
C96.6 Unifocal Langerhans-cell histiocytosis	0.000	0.972	0.027
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.000	0.972	0.027
C96.4 Sarcoma of dendritic cells (accessory cells)	0.000	0.972	0.027
C96.3 True histiocytic lymphoma	0.000	0.972	0.027
C96.2 Malignant mast cell tumour	0.000	0.972	0.027
C96.1 Malignant histiocytosis	0.000	0.972	0.027
C96.0 Letterer-Siwe disease	0.000	0.972	0.027
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.028	0.972	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.000	0.973	0.027
C94.7 Other specified leukaemias	0.000	0.973	0.027
C94.5 Acute myelofibrosis	0.000	0.973	0.027
C94.3 Mast cell leukaemia	0.000	0.973	0.027
C94.2 Acute megakaryoblastic leukaemia	0.000	0.973	0.027
C94.1 Chronic erythraemia	0.000	0.973	0.027
C94.0 Acute erythraemia and erythroleukaemia	0.000	0.973	0.027
C94.4 Acute panmyelosis	0.000	0.973	0.027
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.000	0.974	0.026
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.000	0.974	0.026
C86.4 Blastic NK-cell lymphoma	0.000	0.974	0.026
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.000	0.974	0.026
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.000	0.974	0.026
C86.1 Hepatosplenic T-cell lymphoma	0.000	0.974	0.026
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.000	0.974	0.026
C95.7 Other leukaemia of unspecified cell type	0.000	0.975	0.025
C95.2 Subacute leukaemia of unspecified cell type	0.000	0.975	0.025
C95.0 Acute leukaemia of unspecified cell type	0.000	0.975	0.025
C95.9 Leukaemia, unspecified	0.000	0.975	0.025
C85.1 B-cell lymphoma, unspecified	0.000	0.975	0.025
C77.0 Lymph nodes of head, face and neck	0.000	0.977	0.023
C86.5 Angioimmunoblastic T-cell lymphoma	0.000	0.977	0.023
C95.1 Chronic leukaemia of unspecified cell type	0.000	0.977	0.023
C90.2 Plasmacytoma, extramedullary	0.000	0.978	0.022
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.022	0.978	0.000
C90.1 Plasma cell leukaemia	0.000	0.980	0.020
B18.2 Chronic viral hepatitis C	0.020	0.980	0.000
C90.3 Solitary plasmacytoma	0.000	0.980	0.019
C91 Lymphoid leukaemia	0.000	0.982	0.018
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.018	0.982	0.000
B18 Chronic viral hepatitis	0.017	0.983	0.000
C92.1 Chronic myeloid leukaemia	0.000	0.983	0.016
B15-B19 Viral hepatitis	0.016	0.984	0.000
C91.4 Hairy-cell leukaemia	0.000	0.985	0.015
B17 Other acute viral hepatitis	0.015	0.985	0.000
B17.1 Acute hepatitis C	0.015	0.985	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.014	0.986	0.000
C90.0 Multiple myeloma	0.000	0.986	0.014
M67.8 Other specified disorders of synovium and tendon	0.014	0.986	0.000
B15 Acute hepatitis A	0.014	0.986	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.986	0.014
B16 Acute hepatitis B	0.014	0.986	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.987	0.013
C91.7 Other lymphoid leukaemia	0.000	0.987	0.013
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.987	0.013
C91.3 Prolymphocytic leukaemia	0.000	0.987	0.013
C91.2 Subacute lymphocytic leukaemia	0.000	0.987	0.013
B18.9 Chronic viral hepatitis, unspecified	0.013	0.987	0.000
B15.9 Hepatitis A without hepatic coma	0.013	0.987	0.000
B18.8 Other chronic viral hepatitis	0.012	0.987	0.000
B18.0 Chronic viral hepatitis B with delta-agent	0.012	0.987	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.012	0.988	0.000
B17.8 Other specified acute viral hepatitis	0.012	0.988	0.000
C91.9 Lymphoid leukaemia, unspecified	0.000	0.988	0.011
C91.5 Adult T-cell leukaemia	0.000	0.988	0.011
C91.0 Acute lymphoblastic leukaemia	0.000	0.989	0.011
B18.1 Chronic viral hepatitis B without delta-agent	0.011	0.989	0.000
B17.9 Acute viral hepatitis, unspecified	0.011	0.989	0.000
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.011	0.989	0.000
B17.2 Acute hepatitis E	0.011	0.989	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.989	0.011
B15.0 Hepatitis A with hepatic coma	0.010	0.990	0.000
B19 Unspecified viral hepatitis	0.010	0.990	0.000
C83.6 Undifferentiated (diffuse)	0.000	0.990	0.010
C83.4 Immunoblastic (diffuse)	0.000	0.990	0.010
C83.2 Mixed small and large cell (diffuse)	0.000	0.990	0.010
C83.1 Small cleaved cell (diffuse)	0.000	0.990	0.010
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.010	0.990	0.000
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.010	0.990	0.000
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.010	0.990	0.000
C83.5 Lymphoblastic (diffuse)	0.000	0.990	0.010
C77.2 Intra-abdominal lymph nodes	0.000	0.990	0.010
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.990	0.010
M67 Other disorders of synovium and tendon	0.010	0.990	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.009	0.990	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.009	0.991	0.000
H20.9 Iridocyclitis, unspecified	0.000	0.991	0.009
M67.0 Short Achilles tendon (acquired)	0.008	0.992	0.000
M67.4 Ganglion	0.008	0.992	0.000
C83.0 Small cell (diffuse)	0.000	0.992	0.008
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.992	0.008
C83.7 Burkitt's tumour	0.000	0.992	0.008
B19.0 Unspecified viral hepatitis with coma	0.007	0.992	0.000
C83.3 Large cell (diffuse)	0.000	0.993	0.007
M67.9 Disorder of synovium and tendon, unspecified	0.007	0.993	0.000
M67.3 Transient synovitis	0.007	0.993	0.000
R25.2 Cramp and spasm	0.000	0.993	0.007
M67.43 Ganglion, wrist	0.007	0.993	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.007	0.993	0.000
B19.9 Unspecified viral hepatitis without coma	0.006	0.994	0.000
M67.1 Other contracture of tendon (sheath)	0.006	0.994	0.000
M67.47 Ganglion, ankle and foot	0.006	0.994	0.000
M67.49 Ganglion, multiple sites	0.006	0.994	0.000
M67.45 Ganglion, hip	0.006	0.994	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.000	0.994	0.006
M06.9 Rheumatoid arthritis, unspecified	0.006	0.994	0.000
H43.3 Other vitreous opacities	0.006	0.994	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.006	0.994	0.000
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.005	0.995	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.995	0.005
C34.9 Bronchus or lung, unspecified	0.000	0.995	0.005
M54.39 Sciatica (Site unspecified)	0.005	0.995	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.005	0.995	0.000
R25.3 Fasciculation	0.000	0.995	0.005
M66.2 Spontaneous rupture of extensor tendons	0.005	0.995	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.005	0.995	0.000
M66 Spontaneous rupture of synovium and tendon	0.005	0.995	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.005	0.995	0.000
M65-M68 Disorders of synovium and tendon	0.005	0.995	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.005	0.995	0.000
C34.0 Main bronchus	0.000	0.995	0.005
C34 Malignant neoplasm of bronchus and lung	0.000	0.995	0.005
W13.9 Unspecified place	0.004	0.996	0.000
R25 Abnormal involuntary movements	0.000	0.996	0.004
C34.3 Lower lobe, bronchus or lung	0.000	0.996	0.004
C45 Mesothelioma	0.000	0.996	0.004
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.996	0.004
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.004	0.996	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.996	0.004
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.004	0.996	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.004	0.996	0.000
H43.9 Disorder of vitreous body, unspecified	0.004	0.996	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.004	0.996	0.000
C49.9 Connective and soft tissue, unspecified	0.000	0.996	0.004
M66.3 Spontaneous rupture of flexor tendons	0.004	0.996	0.000
C45.9 Mesothelioma, unspecified	0.000	0.996	0.004
H43 Disorders of vitreous body	0.004	0.996	0.000
M06.3 Rheumatoid nodule	0.004	0.996	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.996	0.004
M66.0 Rupture of popliteal cyst	0.004	0.996	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.004	0.996	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.004	0.996	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.004	0.996	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.004	0.996	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.004	0.996	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.004	0.996	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.004	0.996	0.000
H66 Suppurative and unspecified otitis media	0.000	0.996	0.004
C45.0 Mesothelioma of pleura	0.000	0.996	0.004
M66.1 Rupture of synovium	0.004	0.996	0.000
W19.4 Street and highway	0.004	0.996	0.000
C34.8 Overlapping lesion of bronchus and lung	0.000	0.996	0.004
C49.0 Connective and soft tissue of head, face and neck	0.000	0.996	0.004
M06 Other rheumatoid arthritis	0.004	0.996	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.004	0.996	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.003	0.996	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.004	0.996	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.004	0.996	0.000
M06.34 Rheumatoid nodule (Hand)	0.003	0.996	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
R25.0 Abnormal head movements	0.000	0.997	0.003
R52.1 Chronic intractable pain	0.000	0.997	0.003
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.997	0.003
M66.4 Spontaneous rupture of other tendons	0.003	0.997	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.003	0.997	0.000
C77.3 Axillary and upper limb lymph nodes	0.000	0.997	0.003
H43.1 Vitreous haemorrhage	0.003	0.997	0.000
Chapter II Neoplasms	0.000	0.997	0.003
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.997	0.003
C45.7 Mesothelioma of other sites	0.000	0.997	0.003
M06.32 Rheumatoid nodule (Upper arm)	0.003	0.997	0.000
H20 Iridocyclitis	0.000	0.997	0.003
C49.4 Connective and soft tissue of abdomen	0.000	0.997	0.003
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.003	0.997	0.000
C45.2 Mesothelioma of pericardium	0.000	0.997	0.003
C45.1 Mesothelioma of peritoneum	0.000	0.997	0.003
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.997	0.003
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.003	0.997	0.000
N81.1 Cystocele	0.000	0.997	0.003
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.000	0.997	0.003
H43.2 Crystalline deposits in vitreous body	0.003	0.997	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.003	0.997	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.997	0.003
K35.8 Acute appendicitis, other and unspecified	0.000	0.997	0.003
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.003	0.997	0.000
C46 Kaposi's sarcoma	0.000	0.997	0.003
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.003	0.997	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.997	0.003
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.003	0.997	0.000
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.003	0.997	0.000
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.003	0.997	0.000
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.003	0.997	0.000
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.003	0.997	0.000
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.003	0.997	0.000
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.003	0.997	0.000
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.003	0.997	0.000
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.003	0.997	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.003	0.997	0.000
H43.0 Vitreous prolapse	0.003	0.997	0.000
H66.0 Acute suppurative otitis media	0.000	0.997	0.003
M06.1 Adult-onset Still's disease	0.003	0.997	0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.003	0.997	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.003	0.997	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.003	0.997	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.003	0.997	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.003	0.997	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.000	0.997	0.003
W13 Fall from, out of or through building or structure	0.003	0.997	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.003	0.997	0.000
M06.38 Rheumatoid nodule (Other)	0.003	0.997	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.003	0.997	0.000
M06.33 Rheumatoid nodule (Forearm)	0.003	0.997	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.003	0.997	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.003	0.997	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.003	0.997	0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.003	0.997	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.003	0.997	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.997	0.003
M66.09 Rupture of popliteal cyst-Site unspec	0.003	0.997	0.000
M66.08 Rupture of popliteal cyst-Other	0.003	0.997	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.003	0.997	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.003	0.997	0.000
M66.04 Rupture of popliteal cyst-Hand	0.003	0.997	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.003	0.997	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.003	0.997	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.003	0.997	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.003	0.997	0.000
C48.1 Specified parts of peritoneum	0.000	0.997	0.003
M06.8 Other specified rheumatoid arthritis	0.003	0.997	0.000
M66.19 Rupture of synovium (Site unspecified)	0.003	0.997	0.000
M66.18 Rupture of synovium (Other)	0.003	0.997	0.000
M66.17 Rupture of synovium (Ankle and foot)	0.003	0.997	0.000
M66.16 Rupture of synovium (Lower leg)	0.003	0.997	0.000
M66.15 Rupture of synovium (Pelvic region and thigh)	0.003	0.997	0.000
M66.14 Rupture of synovium (Hand)	0.003	0.997	0.000
M66.13 Rupture of synovium (Forearm)	0.003	0.997	0.000
M66.12 Rupture of synovium (Upper arm)	0.003	0.997	0.000
M66.11 Rupture of synovium (Shoulder region)	0.003	0.997	0.000
M66.10 Rupture of synovium (Multiple sites)	0.003	0.997	0.000
M06.2 Rheumatoid bursitis	0.003	0.997	0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.003	0.997	0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.003	0.997	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.997	0.003
M06.36 Rheumatoid nodule (Lower leg)	0.003	0.997	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.003	0.997	0.000
N85.1 Endometrial adenomatous hyperplasia	0.000	0.997	0.003
H66.4 Suppurative otitis media, unspecified	0.000	0.997	0.003
N75.0 Cyst of Bartholin's gland	0.000	0.997	0.003
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.997	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.003	0.997	0.000
C49.5 Connective and soft tissue of pelvis	0.000	0.997	0.003
C33 Malignant neoplasm of trachea	0.000	0.997	0.003
H20.0 Acute and subacute iridocyclitis	0.000	0.997	0.003
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.997	0.003
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.002	0.997	0.000
M66.48 Spontaneous rupture of other tendons (Other)	0.002	0.997	0.000
M66.44 Spontaneous rupture of other tendons (Hand)	0.002	0.997	0.000
M66.43 Spontaneous rupture of other tendons (Forearm)	0.002	0.997	0.000
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.002	0.997	0.000
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.002	0.997	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.997	0.003
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.002	0.997	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.997	0.003
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.002	0.997	0.000
C47.1 Peripheral nerves of upper limb, including shoulder	0.000	0.997	0.002
H20.2 Lens-induced iridocyclitis	0.000	0.997	0.002
C31 Malignant neoplasm of accessory sinuses	0.000	0.997	0.002
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.997	0.002
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.997	0.003
M06.10 Adult-onset Still's disease (Multiple sites)	0.002	0.997	0.000
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.002	0.997	0.000
W13.4 Street and highway	0.003	0.997	0.000
C47.9 Peripheral nerves and autonomic nervous system, unspecified	0.000	0.997	0.002
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system	0.000	0.997	0.002
C47.6 Peripheral nerves of trunk, unspecified	0.000	0.997	0.002
C47.5 Peripheral nerves of pelvis	0.000	0.997	0.002
C47.4 Peripheral nerves of abdomen	0.000	0.997	0.002
C47.3 Peripheral nerves of thorax	0.000	0.997	0.002
C47.2 Peripheral nerves of lower limb, including hip	0.000	0.997	0.002
C47.0 Peripheral nerves of head, face and neck	0.000	0.997	0.002
Y45.1 Salicylates	0.003	0.997	0.000
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.002	0.997	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.003	0.997	0.000
C46.9 Kaposi's sarcoma, unspecified	0.000	0.997	0.002
C46.8 Kaposi's sarcoma of multiple organs	0.000	0.997	0.002
C46.7 Kaposi's sarcoma of other sites	0.000	0.997	0.002
C46.3 Kaposi's sarcoma of lymph nodes	0.000	0.997	0.002
C46.2 Kaposi's sarcoma of palate	0.000	0.997	0.002
C46.1 Kaposi's sarcoma of soft tissue	0.000	0.997	0.002
C46.0 Kaposi's sarcoma of skin	0.000	0.997	0.002
Y45.0 Opioids and related analgesics	0.003	0.997	0.000
R80 Isolated proteinuria	0.000	0.997	0.003
M19.96 Arthrosis, unspecified-Lower leg	0.003	0.997	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.003	0.997	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.997	0.002
H20.1 Chronic iridocyclitis	0.000	0.997	0.002
M89.98 Disorder of bone, unspecified (Other)	0.002	0.997	0.000
O81.4 Vacuum extractor delivery	0.002	0.997	0.000
C37 Malignant neoplasm of thymus	0.000	0.997	0.002
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.002	0.997	0.000
C49.3 Connective and soft tissue of thorax	0.000	0.997	0.002
D47.1 Chronic myeloproliferative disease	0.000	0.997	0.002
M06.19 Adult-onset Still's disease (Site unspecified)	0.002	0.998	0.000
M06.18 Adult-onset Still's disease (Other)	0.002	0.998	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.002	0.998	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.002	0.998	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.002	0.998	0.000
M06.14 Adult-onset Still's disease (Hand)	0.002	0.998	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.002	0.998	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.002	0.998	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.002	0.998	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.998	0.002
L89.1 Stage II decubitus ulcer	0.002	0.998	0.000
M48.06 Spinal stenosis (Lumbar region)	0.002	0.998	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
S42.10 Fracture of scapula (closed)	0.000	0.998	0.002
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.000	0.998	0.002
M06.4 Inflammatory polyarthropathy	0.002	0.998	0.000
W13.8 Other specified place	0.002	0.998	0.000
W13.0 Home	0.002	0.998	0.000
W13.7 Farm	0.002	0.998	0.000
W13.6 Industrial and construction area	0.002	0.998	0.000
W13.5 Trade and service area	0.002	0.998	0.000
W13.3 Sports and athletics area	0.002	0.998	0.000
W13.2 School, other institution and public administrative area	0.002	0.998	0.000
W13.1 Residential institution	0.002	0.998	0.000
S79.9 Unspecified injury of hip and thigh	0.000	0.998	0.002
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.002	0.998	0.000
M06.28 Rheumatoid bursitis (Other)	0.002	0.998	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.002	0.998	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.002	0.998	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.002	0.998	0.000
M06.24 Rheumatoid bursitis (Hand)	0.002	0.998	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.002	0.998	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.002	0.998	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.002	0.998	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.002	0.998	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.002	0.998	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.002	0.998	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.002	0.998	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.002	0.998	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
H61.8 Other specified disorders of external ear	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.998	0.002
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.998	0.002
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.998	0.002
H61.9 Disorder of external ear, unspecified	0.002	0.998	0.000
J32.4 Chronic pansinusitis	0.002	0.998	0.000
C38.3 Mediastinum, part unspecified	0.000	0.998	0.002
M14.6 Neuropathic arthropathy	0.002	0.998	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.002	0.998	0.000
C48.0 Retroperitoneum	0.000	0.998	0.002
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.998	0.002
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.000	0.998	0.002
W17.5 Trade and service area	0.002	0.998	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.002	0.998	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.998	0.002
C38.2 Posterior mediastinum	0.000	0.998	0.002
C38.1 Anterior mediastinum	0.000	0.998	0.002
C38.0 Heart	0.000	0.998	0.002
C39.9 Ill-defined sites within the respiratory system	0.000	0.998	0.002
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.998	0.002
C39.0 Upper respiratory tract, part unspecified	0.000	0.998	0.002
S73.0 Dislocation of hip	0.000	0.998	0.002
H61 Other disorders of external ear	0.002	0.998	0.000
W17 Other fall from one level to another	0.002	0.998	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.000	0.998	0.002
M06.46 Inflammatory polyarthropathy (Lower leg)	0.002	0.998	0.000
H43.8 Other disorders of vitreous body	0.000	0.998	0.002
W17.6 Industrial and construction area	0.002	0.998	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.998	0.002
I46.0 Cardiac arrest with successful resuscitation	0.002	0.998	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
C30.1 Middle ear	0.000	0.998	0.002
C31.9 Accessory sinus, unspecified	0.000	0.998	0.002
C31.8 Overlapping lesion of accessory sinuses	0.000	0.998	0.002
C31.3 Sphenoidal sinus	0.000	0.998	0.002
C31.2 Frontal sinus	0.000	0.998	0.002
C31.1 Ethmoidal sinus	0.000	0.998	0.002
H20.8 Other iridocyclitis	0.000	0.998	0.002
M14 Arthropathies in other diseases classified elsewhere	0.002	0.998	0.000
C38.4 Pleura	0.000	0.998	0.002
I46.9 Cardiac arrest, unspecified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations