TreeWAS – Variant ID: rs435066

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H80.9 Otosclerosis, unspecified	0.000	0.981	0.019
H83.0 Labyrinthitis	0.000	0.983	0.017
H80 Otosclerosis	0.000	0.983	0.017
H83 Other diseases of inner ear	0.000	0.985	0.015
H80-H83 Diseases of inner ear	0.000	0.985	0.015
Y86 Sequelae of other accidents	0.000	0.987	0.013
H80.8 Other otosclerosis	0.000	0.988	0.012
H80.2 Cochlear otosclerosis	0.000	0.988	0.012
H80.1 Otosclerosis involving oval window, obliterative	0.000	0.988	0.012
H80.0 Otosclerosis involving oval window, nonobliterative	0.000	0.988	0.012
H83.8 Other specified diseases of inner ear	0.000	0.989	0.011
H83.2 Labyrinthine dysfunction	0.000	0.989	0.011
H83.1 Labyrinthine fistula	0.000	0.989	0.011
H81 Disorders of vestibular function	0.000	0.989	0.011
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.989	0.011
D70 Agranulocytosis	0.011	0.989	0.000
H83.3 Noise effects on inner ear	0.000	0.990	0.010
H83.9 Disease of inner ear, unspecified	0.000	0.990	0.010
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.010	0.990	0.000
H81.9 Disorder of vestibular function, unspecified	0.000	0.990	0.010
M89.8 Other specified disorders of bone	0.009	0.991	0.000
Z22.3 Carrier of other specified bacterial diseases	0.000	0.991	0.009
M89 Other disorders of bone	0.009	0.991	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.008	0.992	0.000
H81.8 Other disorders of vestibular function	0.000	0.992	0.008
M89.87 Other specified disorders of bone (Ankle and foot)	0.008	0.992	0.000
H81.2 Vestibular neuronitis	0.000	0.992	0.008
H81.4 Vertigo of central origin	0.000	0.992	0.008
H81.1 Benign paroxysmal vertigo	0.000	0.992	0.008
M89.0 Algoneurodystrophy	0.008	0.992	0.000
M89.88 Other specified disorders of bone (Other)	0.008	0.992	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.007	0.992	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.007	0.993	0.000
H81.3 Other peripheral vertigo	0.000	0.993	0.007
M89.84 Other specified disorders of bone (Hand)	0.007	0.993	0.000
M89.5 Osteolysis	0.007	0.993	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.007	0.993	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.007	0.993	0.000
M89.83 Other specified disorders of bone (Forearm)	0.007	0.993	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.007	0.993	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.007	0.993	0.000
M89.9 Disorder of bone, unspecified	0.007	0.993	0.000
M89.3 Hypertrophy of bone	0.007	0.993	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.007	0.993	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.007	0.993	0.000
M89.6 Osteopathy after poliomyelitis	0.006	0.993	0.000
M89.2 Other disorders of bone development and growth	0.006	0.993	0.000
M89.1 Epiphyseal arrest	0.006	0.993	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.006	0.994	0.000
M89.03 Algoneurodystrophy (Forearm)	0.006	0.994	0.000
M89.04 Algoneurodystrophy (Hand)	0.006	0.994	0.000
Z90.6 Acquired absence of other parts of urinary tract	0.006	0.994	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.006	0.994	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.006	0.994	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.006	0.994	0.000
H81.0 Meniere's disease	0.000	0.994	0.006
R26.3 Immobility	0.000	0.994	0.006
Q54 Hypospadias	0.006	0.994	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.006	0.994	0.000
Q54.1 Hypospadias, penile	0.006	0.994	0.000
M89.08 Algoneurodystrophy (Other)	0.006	0.994	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.006	0.994	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.006	0.994	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.006	0.994	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.006	0.994	0.000
F22.0 Delusional disorder	0.006	0.994	0.000
Q50-Q56 Congenital malformations of genital organs	0.006	0.994	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.006	0.994	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.994	0.006
Q76 Congenital malformations of spine and bony thorax	0.006	0.994	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.006	0.994	0.000
M89.98 Disorder of bone, unspecified (Other)	0.006	0.994	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.006	0.994	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.005	0.994	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.005	0.994	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.005	0.994	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.005	0.994	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.005	0.994	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.005	0.994	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.005	0.994	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.005	0.994	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.005	0.994	0.000
R79.8 Other specified abnormal findings of blood chemistry	0.006	0.994	0.000
F22 Persistent delusional disorders	0.006	0.994	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.005	0.994	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.005	0.995	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.995	0.005
K25 Gastric ulcer	0.005	0.995	0.000
M89.38 Hypertrophy of bone (Other)	0.005	0.995	0.000
M89.59 Osteolysis (Site unspecified)	0.005	0.995	0.000
M89.58 Osteolysis (Other)	0.005	0.995	0.000
M89.57 Osteolysis (Ankle and foot)	0.005	0.995	0.000
M89.56 Osteolysis (Lower leg)	0.005	0.995	0.000
M89.54 Osteolysis (Hand)	0.005	0.995	0.000
M89.53 Osteolysis (Forearm)	0.005	0.995	0.000
M89.52 Osteolysis (Upper arm)	0.005	0.995	0.000
M89.51 Osteolysis (Shoulder region)	0.005	0.995	0.000
M89.50 Osteolysis (Multiple sites)	0.005	0.995	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.005	0.995	0.000
F20.0 Paranoid schizophrenia	0.005	0.995	0.000
F20 Schizophrenia	0.005	0.995	0.000
F29 Unspecified nonorganic psychosis	0.005	0.995	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.005	0.995	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.005	0.995	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.005	0.995	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.005	0.995	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.005	0.995	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.005	0.995	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.005	0.995	0.000
M89.34 Hypertrophy of bone (Hand)	0.005	0.995	0.000
M89.33 Hypertrophy of bone (Forearm)	0.005	0.995	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.005	0.995	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.005	0.995	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.005	0.995	0.000
F23 Acute and transient psychotic disorders	0.005	0.995	0.000
Q54.9 Hypospadias, unspecified	0.005	0.995	0.000
Q51 Congenital malformations of uterus and cervix	0.005	0.995	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.005	0.995	0.000
K25.7 Chronic without haemorrhage or perforation	0.005	0.995	0.000
R79 Other abnormal findings of blood chemistry	0.005	0.995	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.005	0.995	0.000
M89.18 Epiphyseal arrest (Other)	0.005	0.995	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.005	0.995	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.005	0.995	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.005	0.995	0.000
M89.14 Epiphyseal arrest (Hand)	0.005	0.995	0.000
M89.13 Epiphyseal arrest (Forearm)	0.005	0.995	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.005	0.995	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.005	0.995	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.005	0.995	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.005	0.995	0.000
M89.28 Other disorders of bone development and growth (Other)	0.005	0.995	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.005	0.995	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.005	0.995	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.005	0.995	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.005	0.995	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.005	0.995	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.005	0.995	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.005	0.995	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.005	0.995	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.005	0.995	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.005	0.995	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.005	0.995	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.005	0.995	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.005	0.995	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.005	0.995	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.005	0.995	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.005	0.995	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.005	0.995	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.005	0.995	0.000
Q52 Other congenital malformations of female genitalia	0.005	0.995	0.000
Q54.0 Hypospadias, balanic	0.005	0.995	0.000
Q55 Other congenital malformations of male genital organs	0.005	0.995	0.000
I46.9 Cardiac arrest, unspecified	0.005	0.995	0.000
K25.4 Chronic or unspecified with haemorrhage	0.005	0.995	0.000
Q66 Congenital deformities of feet	0.005	0.995	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.005	0.995	0.000
Q85 Phakomatoses, not elsewhere classified	0.005	0.995	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.005	0.995	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.005	0.995	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.005	0.995	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
Q65 Congenital deformities of hip	0.005	0.995	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.004	0.995	0.000
Q54.8 Other hypospadias	0.004	0.995	0.000
Q54.4 Congenital chordee	0.004	0.995	0.000
Q54.3 Hypospadias, perineal	0.004	0.995	0.000
Q54.2 Hypospadias, penoscrotal	0.004	0.995	0.000
Z50.8 Care involving use of rehabilitation procedures	0.000	0.995	0.005
M87 Osteonecrosis	0.005	0.995	0.000
Q74 Other congenital malformations of limb(s)	0.004	0.995	0.000
M86-M90 Other osteopathies	0.005	0.995	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.004	0.995	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.996	0.004
M87.9 Osteonecrosis, unspecified	0.004	0.996	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.004	0.996	0.000
Q78 Other osteochondrodysplasias	0.004	0.996	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
F22.9 Persistent delusional disorder, unspecified	0.004	0.996	0.000
K25.5 Chronic or unspecified with perforation	0.004	0.996	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
Q75 Other congenital malformations of skull and face bones	0.004	0.996	0.000
Q73 Reduction defects of unspecified limb	0.004	0.996	0.000
Q72 Reduction defects of lower limb	0.004	0.996	0.000
Q71 Reduction defects of upper limb	0.004	0.996	0.000
Q70 Syndactyly	0.004	0.996	0.000
Q69 Polydactyly	0.004	0.996	0.000
Q68 Other congenital musculoskeletal deformities	0.004	0.996	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.004	0.996	0.000
Q76.8 Other congenital malformations of bony thorax	0.004	0.996	0.000
Q76.7 Congenital malformation of sternum	0.004	0.996	0.000
Q76.6 Other congenital malformations of ribs	0.004	0.996	0.000
Q76.5 Cervical rib	0.004	0.996	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.004	0.996	0.000
Q76.2 Congenital spondylolisthesis	0.004	0.996	0.000
Q76.1 Klippel-Feil syndrome	0.004	0.996	0.000
R79.0 Abnormal level of blood mineral	0.004	0.996	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.004	0.996	0.000
F22.8 Other persistent delusional disorders	0.004	0.996	0.000
M87.2 Osteonecrosis due to previous trauma	0.004	0.996	0.000
Q52.1 Doubling of vagina	0.004	0.996	0.000
F20.5 Residual schizophrenia	0.004	0.996	0.000
Q55.0 Absence and aplasia of testis	0.004	0.996	0.000
F28 Other nonorganic psychotic disorders	0.004	0.996	0.000
F24 Induced delusional disorder	0.004	0.996	0.000
F21 Schizotypal disorder	0.004	0.996	0.000
Q80-Q89 Other congenital malformations	0.004	0.996	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.004	0.996	0.000
K25.2 Acute with both haemorrhage and perforation	0.004	0.996	0.000
K25.1 Acute with perforation	0.004	0.996	0.000
Q53 Undescended testicle	0.004	0.996	0.000
Q79.6 Ehlers-Danlos syndrome	0.004	0.996	0.000
F20.8 Other schizophrenia	0.004	0.996	0.000
F20.6 Simple schizophrenia	0.004	0.996	0.000
F20.4 Postschizophrenic depression	0.004	0.996	0.000
F20.3 Undifferentiated schizophrenia	0.004	0.996	0.000
F20.2 Catatonic schizophrenia	0.004	0.996	0.000
F20.1 Hebephrenic schizophrenia	0.004	0.996	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.004	0.996	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.004	0.996	0.000
S52.50 Fracture of lower end of radius (closed)	0.000	0.996	0.004
Q51.3 Bicornate uterus	0.004	0.996	0.000
F20.9 Schizophrenia, unspecified	0.004	0.996	0.000
Q85.9 Phakomatosis, unspecified	0.004	0.996	0.000
Q51.2 Other doubling of uterus	0.004	0.996	0.000
Q66.3 Other congenital varus deformities of feet	0.004	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.004	0.996	0.000
F23.8 Other acute and transient psychotic disorders	0.004	0.996	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.004	0.996	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.004	0.996	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.004	0.996	0.000
N03.9 Unspecified	0.004	0.996	0.000
R26 Abnormalities of gait and mobility	0.000	0.996	0.004
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.004	0.996	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.004	0.996	0.000
Q51.6 Embryonic cyst of cervix	0.004	0.996	0.000
Q51.5 Agenesis and aplasia of cervix	0.004	0.996	0.000
Q51.4 Unicornate uterus	0.004	0.996	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.004	0.996	0.000
Q51.0 Agenesis and aplasia of uterus	0.004	0.996	0.000
Q67.6 Pectus excavatum	0.004	0.996	0.000
Q65.8 Other congenital deformities of hip	0.004	0.996	0.000
Q66.2 Metatarsus varus	0.004	0.996	0.000
F25 Schizoaffective disorders	0.004	0.996	0.000
Q76.0 Spina bifida occulta	0.004	0.996	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.004	0.996	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.004	0.996	0.000
Q52.7 Other congenital malformations of vulva	0.004	0.996	0.000
Q52.6 Congenital malformation of clitoris	0.004	0.996	0.000
Q52.5 Fusion of labia	0.004	0.996	0.000
Q52.4 Other congenital malformations of vagina	0.004	0.996	0.000
Q52.3 Imperforate hymen	0.004	0.996	0.000
Q52.2 Congenital rectovaginal fistula	0.004	0.996	0.000
Q52.0 Congenital absence of vagina	0.004	0.996	0.000
Q66.8 Other congenital deformities of feet	0.004	0.996	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.004	0.996	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.004	0.996	0.000
Q55.6 Other congenital malformations of penis	0.004	0.996	0.000
Q55.5 Congenital absence and aplasia of penis	0.004	0.996	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.004	0.996	0.000
Q55.3 Atresia of vas deferens	0.004	0.996	0.000
Q55.1 Hypoplasia of testis and scrotum	0.004	0.996	0.000
Q66.7 Pes cavus	0.004	0.996	0.000
Q67.5 Congenital deformity of spine	0.004	0.996	0.000
C69.3 Choroid	0.004	0.996	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.996	0.004
Q66.9 Congenital deformity of feet, unspecified	0.004	0.996	0.000
Q66.6 Other congenital valgus deformities of feet	0.004	0.996	0.000
Q66.5 Congenital pes planus	0.004	0.996	0.000
Q66.4 Talipes calcaneovalgus	0.004	0.996	0.000
Q66.1 Talipes calcaneovarus	0.004	0.996	0.000
Q66.0 Talipes equinovarus	0.004	0.996	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.004	0.996	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.004	0.996	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.004	0.996	0.000
Q79.5 Other congenital malformations of abdominal wall	0.004	0.996	0.000
Q79.4 Prune belly syndrome	0.004	0.996	0.000
Q79.3 Gastroschisis	0.004	0.996	0.000
Q79.2 Exomphalos	0.004	0.996	0.000
Q79.1 Other congenital malformations of diaphragm	0.004	0.996	0.000
Q79.0 Congenital diaphragmatic hernia	0.004	0.996	0.000
Q85.1 Tuberous sclerosis	0.004	0.996	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.004	0.996	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.996	0.004
Q67.8 Other congenital deformities of chest	0.003	0.996	0.000
Q67.7 Pectus carinatum	0.003	0.996	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.003	0.996	0.000
Q67.3 Plagiocephaly	0.003	0.996	0.000
Q67.2 Dolichocephaly	0.003	0.996	0.000
Q67.1 Compression facies	0.003	0.996	0.000
Q67.0 Facial asymmetry	0.003	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
Q74.1 Congenital malformation of knee	0.003	0.996	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.003	0.996	0.000
C71.1 Frontal lobe	0.004	0.996	0.000
Q65.9 Congenital deformity of hip, unspecified	0.003	0.996	0.000
Q65.6 Unstable hip	0.003	0.996	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.003	0.996	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.003	0.996	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.003	0.996	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.003	0.996	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.003	0.996	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.003	0.996	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.004	0.996	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.996	0.004
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.000	0.996	0.004
M87.3 Other secondary osteonecrosis	0.003	0.996	0.000
M87.1 Osteonecrosis due to drugs	0.003	0.996	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.003	0.996	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.003	0.996	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.003	0.996	0.000
J15.2 Pneumonia due to staphylococcus	0.004	0.996	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.003	0.996	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.003	0.996	0.000
Q74.3 Arthrogryposis multiplex congenita	0.003	0.996	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.003	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.996	0.000
C71.9 Brain, unspecified	0.004	0.996	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.003	0.996	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.003	0.996	0.000
Q50.5 Embryonic cyst of broad ligament	0.003	0.996	0.000
Q50.3 Other congenital malformations of ovary	0.003	0.996	0.000
Q50.2 Congenital torsion of ovary	0.003	0.996	0.000
Q50.1 Developmental ovarian cyst	0.003	0.996	0.000
Q50.0 Congenital absence of ovary	0.003	0.996	0.000
Q78.0 Osteogenesis imperfecta	0.003	0.996	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.003	0.997	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.003	0.997	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.003	0.997	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.003	0.997	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.003	0.997	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.003	0.997	0.000
Q56.4 Indeterminate sex, unspecified	0.003	0.997	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.003	0.997	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.003	0.997	0.000
Q78.8 Other specified osteochondrodysplasias	0.003	0.997	0.000
Q78.6 Multiple congenital exostoses	0.003	0.997	0.000
Q78.5 Metaphyseal dysplasia	0.003	0.997	0.000
Q78.4 Enchondromatosis	0.003	0.997	0.000
Q78.3 Progressive diaphyseal dysplasia	0.003	0.997	0.000
Q78.2 Osteopetrosis	0.003	0.997	0.000
Q78.1 Polyostotic fibrous dysplasia	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
C69 Malignant neoplasm of eye and adnexa	0.003	0.997	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.997	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.997	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.997	0.000
Q68.3 Congenital bowing of femur	0.003	0.997	0.000
Q68.2 Congenital deformity of knee	0.003	0.997	0.000
Q68.1 Congenital deformity of hand	0.003	0.997	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.997	0.000
Q69.9 Polydactyly, unspecified	0.003	0.997	0.000
Q69.2 Accessory toe(s)	0.003	0.997	0.000
Q69.1 Accessory thumb(s)	0.003	0.997	0.000
Q69.0 Accessory finger(s)	0.003	0.997	0.000
Q70.9 Syndactyly, unspecified	0.003	0.997	0.000
Q70.4 Polysyndactyly	0.003	0.997	0.000
Q70.3 Webbed toes	0.003	0.997	0.000
Q70.2 Fused toes	0.003	0.997	0.000
Q70.1 Webbed fingers	0.003	0.997	0.000
Q70.0 Fused fingers	0.003	0.997	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.003	0.997	0.000
Q71.8 Other reduction defects of upper limb(s)	0.003	0.997	0.000
Q71.6 Lobster-claw hand	0.003	0.997	0.000
Q71.5 Longitudinal reduction defect of ulna	0.003	0.997	0.000
Q71.4 Longitudinal reduction defect of radius	0.003	0.997	0.000
Q71.3 Congenital absence of hand and finger(s)	0.003	0.997	0.000
Q71.2 Congenital absence of both forearm and hand	0.003	0.997	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.003	0.997	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.003	0.997	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.003	0.997	0.000
Q72.8 Other reduction defects of lower limb(s)	0.003	0.997	0.000
Q72.7 Split foot	0.003	0.997	0.000
Q72.6 Longitudinal reduction defect of fibula	0.003	0.997	0.000
Q72.5 Longitudinal reduction defect of tibia	0.003	0.997	0.000
Q72.4 Longitudinal reduction defect of femur	0.003	0.997	0.000
Q72.3 Congenital absence of foot and toe(s)	0.003	0.997	0.000
Q72.2 Congenital absence of both lower leg and foot	0.003	0.997	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.003	0.997	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.003	0.997	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.003	0.997	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.003	0.997	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.003	0.997	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.003	0.997	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.003	0.997	0.000
Q75.5 Oculomandibular dysostosis	0.003	0.997	0.000
Q75.4 Mandibulofacial dysostosis	0.003	0.997	0.000
Q75.3 Macrocephaly	0.003	0.997	0.000
Q75.2 Hypertelorism	0.003	0.997	0.000
Q75.1 Craniofacial dysostosis	0.003	0.997	0.000
Q75.0 Craniosynostosis	0.003	0.997	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.003	0.997	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.003	0.997	0.000
Q77.6 Chondroectodermal dysplasia	0.003	0.997	0.000
Q77.5 Diastrophic dysplasia	0.003	0.997	0.000
Q77.4 Achondroplasia	0.003	0.997	0.000
Q77.3 Chondrodysplasia punctata	0.003	0.997	0.000
Q77.2 Short rib syndrome	0.003	0.997	0.000
Q77.1 Thanatophoric short stature	0.003	0.997	0.000
Q77.0 Achondrogenesis	0.003	0.997	0.000
M90 Osteopathies in diseases classified elsewhere	0.003	0.997	0.000
Q35 Cleft palate	0.003	0.997	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.003	0.997	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.003	0.997	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.003	0.997	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.003	0.997	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.003	0.997	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.003	0.997	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.003	0.997	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.003	0.997	0.000
K25.0 Acute with haemorrhage	0.003	0.997	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.997	0.003
M87.8 Other osteonecrosis	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.003	0.997	0.000
Q84 Other congenital malformations of integument	0.003	0.997	0.000
Q81 Epidermolysis bullosa	0.003	0.997	0.000
Q80 Congenital ichthyosis	0.003	0.997	0.000
Q53.9 Undescended testicle, unspecified	0.003	0.997	0.000
Q53.2 Undescended testicle, bilateral	0.003	0.997	0.000
Q53.0 Ectopic testis	0.003	0.997	0.000
C69.9 Eye, unspecified	0.003	0.997	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.003	0.997	0.000
M88 Paget's disease of bone [osteitis deformans]	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.003	0.997	0.000
C71 Malignant neoplasm of brain	0.003	0.997	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.003	0.997	0.000
Chapter VIII Diseases of the ear and mastoid process	0.000	0.997	0.003
M87.96 Osteonecrosis, unspecified (Lower leg)	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q89 Other congenital malformations, not elsewhere classified	0.003	0.997	0.000
F25.9 Schizoaffective disorder, unspecified	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
R26.1 Paralytic gait	0.000	0.997	0.003
H73 Other disorders of tympanic membrane	0.000	0.997	0.003
Q37 Cleft palate with cleft lip	0.003	0.997	0.000
Q36 Cleft lip	0.003	0.997	0.000
R26.0 Ataxic gait	0.000	0.997	0.003
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Q82 Other congenital malformations of skin	0.003	0.997	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.997	0.003
Q44.5 Other congenital malformations of bile ducts	0.003	0.997	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
K25.3 Acute without haemorrhage or perforation	0.003	0.997	0.000
Q35.9 Cleft palate, unspecified	0.003	0.997	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.997	0.003
F25.8 Other schizoaffective disorders	0.003	0.997	0.000
F25.2 Schizoaffective disorder, mixed type	0.003	0.997	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.003	0.997	0.000
S72.10 Pertrochanteric fracture (closed)	0.003	0.997	0.000
N20.1 Calculus of ureter	0.003	0.997	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.000	0.997	0.003
O69.4 Labour and delivery complicated by vasa praevia	0.000	0.997	0.003
O69.3 Labour and delivery complicated by short cord	0.000	0.997	0.003
Q53.1 Undescended testicle, unilateral	0.003	0.997	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.003	0.997	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.000	0.997	0.003
D74 Methaemoglobinaemia	0.003	0.997	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.003	0.997	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
Q90 Down's syndrome	0.003	0.997	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.997	0.000
Q33 Congenital malformations of lung	0.003	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.997	0.000
Q31 Congenital malformations of larynx	0.003	0.997	0.000
Q30 Congenital malformations of nose	0.003	0.997	0.000
Q44.6 Cystic disease of liver	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
F60.9 Personality disorder, unspecified	0.003	0.997	0.000
Q45.8 Other specified congenital malformations of digestive system	0.003	0.997	0.000
D76.3 Other histiocytosis syndromes	0.003	0.997	0.000
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.003	0.997	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.003	0.997	0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.003	0.997	0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.003	0.997	0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.003	0.997	0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.003	0.997	0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.003	0.997	0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.003	0.997	0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.003	0.997	0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations