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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4455710
log Bayes Factor = 227.625
Chromosome 6   position 32,608,858  (GRCh37) Explore rs4455710 on Ensembl!
Variant rs4455710 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
C83 Diffuse non-Hodgkin's lymphoma
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
1.000 0.000 0.000
C83.3 Large cell (diffuse)
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.999 0.001 0.000
D60-D64 Aplastic and other anaemias
0.999 0.001 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.999 0.001 0.000
L40.9 Psoriasis, unspecified
0.000 0.001 0.999
H00.1 Chalazion
0.000 0.001 0.999
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.999 0.001 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.999 0.001 0.000
C44.7 Skin of lower limb, including hip
0.999 0.001 0.000
L57.0 Actinic keratosis
0.999 0.001 0.000
D64 Other anaemias
0.999 0.001 0.000
D64.9 Anaemia, unspecified
0.998 0.002 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.997 0.003 0.000
C44.6 Skin of upper limb, including shoulder
0.997 0.003 0.000
H36.0 Diabetic retinopathy
0.996 0.004 0.000
K90 Intestinal malabsorption
0.996 0.004 0.000
E10.1 With ketoacidosis
0.995 0.005 0.000
E14 Unspecified diabetes mellitus
0.995 0.005 0.000
Chapter VII Diseases of the eye and adnexa
0.995 0.005 0.000
H36 Retinal disorders in diseases classified elsewhere
0.993 0.007 0.000
C44.0 Skin of lip
0.993 0.007 0.000
H30-H36 Disorders of choroid and retina
0.992 0.008 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.990 0.010 0.000
E14.3 With ophthalmic complications
0.988 0.012 0.000
L40-L45 Papulosquamous disorders
0.984 0.012 0.004
C81 Hodgkin's disease
0.987 0.013 0.000
C44.2 Skin of ear and external auricular canal
0.984 0.016 0.000
C44.4 Skin of scalp and neck
0.983 0.017 0.000
E20-E35 Disorders of other endocrine glands
0.981 0.019 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.981 0.019 0.000
D69 Purpura and other haemorrhagic conditions
0.980 0.020 0.000
Chapter XI Diseases of the digestive system
0.979 0.021 0.000
K90-K93 Other diseases of the digestive system
0.978 0.022 0.000
L43 Lichen planus
0.976 0.022 0.001
M35.0 Sicca syndrome [Sjogren]
0.977 0.023 0.000
E10.4 With neurological complications
0.977 0.023 0.000
E10.2 With renal complications
0.977 0.023 0.000
K50-K52 Noninfective enteritis and colitis
0.977 0.023 0.000
C85.1 B-cell lymphoma, unspecified
0.974 0.026 0.000
H50 Other strabismus
0.973 0.027 0.000
L43.9 Lichen planus, unspecified
0.970 0.030 0.000
K52 Other non-infective gastro-enteritis and colitis
0.965 0.035 0.000
K51 Ulcerative colitis
0.965 0.035 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.965 0.035 0.000
K51.9 Ulcerative colitis, unspecified
0.963 0.037 0.000
C44.5 Skin of trunk
0.962 0.038 0.000
D00-D09 In situ neoplasms
0.958 0.042 0.000
C81.1 Nodular sclerosis
0.954 0.046 0.000
K90.9 Intestinal malabsorption, unspecified
0.952 0.048 0.000
D04 Carcinoma in situ of skin
0.951 0.049 0.000
E28 Ovarian dysfunction
0.947 0.053 0.000
D61 Other aplastic anaemias
0.943 0.057 0.000
M35 Other systemic involvement of connective tissue
0.938 0.062 0.000
E07 Other disorders of thyroid
0.936 0.064 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.933 0.067 0.000
M20-M25 Other joint disorders
0.931 0.069 0.000
M34 Systemic sclerosis
0.928 0.072 0.000
H50.0 Convergent concomitant strabismus
0.927 0.073 0.000
E27 Other disorders of adrenal gland
0.918 0.082 0.000
M24 Other specific joint derangements
0.912 0.088 0.000
C81.9 Hodgkin's disease, unspecified
0.912 0.088 0.000
D69.6 Thrombocytopenia, unspecified
0.909 0.091 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.909 0.091 0.000
D04.5 Skin of trunk
0.904 0.096 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.902 0.098 0.000
M34.9 Systemic sclerosis, unspecified
0.900 0.100 0.000
E27.1 Primary adrenocortical insufficiency
0.897 0.103 0.000
K51.4 Pseudopolyposis of colon
0.896 0.104 0.000
E07.9 Disorder of thyroid, unspecified
0.890 0.110 0.000
H40-H42 Glaucoma
0.887 0.113 0.000
L10-L14 Bullous disorders
0.885 0.115 0.000
E16 Other disorders of pancreatic internal secretion
0.884 0.116 0.000
D68 Other coagulation defects
0.880 0.120 0.000
M24.1 Other articular cartilage disorders
0.880 0.120 0.000
D61.9 Aplastic anaemia, unspecified
0.879 0.121 0.000
E10.0 With coma
0.878 0.122 0.000
E10.5 With peripheral circulatory complications
0.878 0.122 0.000
E28.2 Polycystic ovarian syndrome
0.876 0.124 0.000
C44.1 Skin of eyelid, including canthus
0.873 0.127 0.000
M15-M19 Arthrosis
0.872 0.128 0.000
M18 Arthrosis of first carpometacarpal joint
0.871 0.129 0.000
E14.4 With neurological complications
0.869 0.131 0.000
M34.1 CR(E)ST syndrome
0.868 0.132 0.000
H00 Hordeolum and chalazion
0.053 0.137 0.811
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.862 0.138 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.862 0.138 0.000
D04.7 Skin of lower limb, including hip
0.861 0.139 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.861 0.139 0.000
E06 Thyroiditis
0.859 0.141 0.000
H50.5 Heterophoria
0.858 0.142 0.000
L82 Seborrhoeic keratosis
0.858 0.142 0.000
E28.3 Primary ovarian failure
0.856 0.144 0.000
C83.7 Burkitt's tumour
0.847 0.153 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.843 0.157 0.000
D04.4 Skin of scalp and neck
0.843 0.157 0.000
C82.2 Large cell, follicular
0.839 0.161 0.000
E16.2 Hypoglycaemia, unspecified
0.838 0.162 0.000
C43 Malignant melanoma of skin
0.836 0.164 0.000
E14.5 With peripheral circulatory complications
0.834 0.166 0.000
L94 Other localised connective tissue disorders
0.832 0.168 0.000
D68.8 Other specified coagulation defects
0.831 0.169 0.000
H49 Paralytic strabismus
0.829 0.171 0.000
H50.9 Strabismus, unspecified
0.826 0.174 0.000
D69.4 Other primary thrombocytopenia
0.823 0.177 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.823 0.177 0.000
K70-K77 Diseases of liver
0.817 0.183 0.000
C82.0 Small cleaved cell, follicular
0.816 0.184 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.816 0.184 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.813 0.187 0.000
N00-N08 Glomerular diseases
0.813 0.187 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.813 0.187 0.000
K52.1 Toxic gastro-enteritis and colitis
0.812 0.188 0.000
H40 Glaucoma
0.810 0.190 0.000
E14.8 With unspecified complications
0.808 0.192 0.000
D69.2 Other nonthrombocytopenic purpura
0.807 0.193 0.000
K75 Other inflammatory liver diseases
0.807 0.193 0.000
N05 Unspecified nephritic syndrome
0.807 0.193 0.000
N04 Nephrotic syndrome
0.806 0.194 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.798 0.202 0.000
C83.1 Small cleaved cell (diffuse)
0.798 0.202 0.000
H40.1 Primary open-angle glaucoma
0.797 0.203 0.000
E20 Hypoparathyroidism
0.796 0.204 0.000
M15 Polyarthrosis
0.796 0.204 0.000
C69 Malignant neoplasm of eye and adnexa
0.793 0.207 0.000
D68.6 Other Thrombophilia
0.792 0.208 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.792 0.208 0.000
D06 Carcinoma in situ of cervix uteri
0.791 0.209 0.000
L57.4 Cutis laxa senilis
0.790 0.210 0.000
K75.4 Autoimmune hepatitis
0.790 0.210 0.000
C82.4 Follicular lymphoma grade IIIb
0.789 0.211 0.000
M35.7 Hypermobility syndrome
0.789 0.211 0.000
L12 Pemphigoid
0.789 0.211 0.000
D64.3 Other sideroblastic anaemias
0.789 0.211 0.000
M34.8 Other forms of systemic sclerosis
0.788 0.212 0.000
L83 Acanthosis nigricans
0.786 0.214 0.000
K90.8 Other intestinal malabsorption
0.785 0.215 0.000
E06.3 Autoimmune thyroiditis
0.784 0.216 0.000
H50.6 Mechanical strabismus
0.783 0.217 0.000
H50.3 Intermittent heterotropia
0.782 0.218 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.782 0.218 0.000
H50.8 Other specified strabismus
0.778 0.222 0.000
E03.8 Other specified hypothyroidism
0.777 0.223 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.777 0.223 0.000
L42 Pityriasis rosea
0.773 0.225 0.002
N04.9 Unspecified
0.774 0.226 0.000
H30 Chorioretinal inflammation
0.772 0.228 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.772 0.228 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.772 0.228 0.000
E31 Polyglandular dysfunction
0.768 0.232 0.000
D03 Melanoma in situ
0.767 0.233 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.764 0.236 0.000
M60-M63 Disorders of muscles
0.763 0.237 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.762 0.238 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.761 0.239 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.010 0.239 0.752
D04.2 Skin of ear and external auricular canal
0.759 0.241 0.000
C43.4 Malignant melanoma of scalp and neck
0.759 0.241 0.000
H50.2 Vertical strabismus
0.758 0.242 0.000
M24.0 Loose body in joint
0.757 0.243 0.000
E10.7 With multiple complications
0.755 0.245 0.000
E14.1 With ketoacidosis
0.754 0.246 0.000
N05.2 Diffuse membranous glomerulonephritis
0.754 0.246 0.000
C88 Malignant immunoproliferative diseases
0.754 0.246 0.000
D64.8 Other specified anaemias
0.754 0.246 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.753 0.247 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.753 0.247 0.000
E14.2 Withrenal complications
0.752 0.248 0.000
L40 Psoriasis
0.099 0.249 0.651
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.747 0.253 0.000
D69.8 Other specified haemorrhagic conditions
0.747 0.253 0.000
L94.0 Localised scleroderma [morphea]
0.746 0.254 0.000
C81.0 Lymphocytic predominance
0.745 0.254 0.000
E26 Hyperaldosteronism
0.744 0.256 0.000
N03 Chronic nephritic syndrome
0.744 0.256 0.000
D80-D89 Certain disorders involving the immune mechanism
0.744 0.256 0.000
M24.5 Contracture of joint
0.743 0.257 0.000
H50.4 Other and unspecified heterotropia
0.742 0.258 0.000
D61.1 Drug-induced aplastic anaemia
0.741 0.259 0.000
D69.0 Allergic purpura
0.740 0.260 0.000
E22 Hyperfunction of pituitary gland
0.738 0.262 0.000
D64.0 Hereditary sideroblastic anaemia
0.735 0.264 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.735 0.265 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.735 0.265 0.000
L43.8 Other lichen planus
0.733 0.266 0.001
D69.1 Qualitative platelet defects
0.733 0.267 0.000
H43-H45 Disorders of vitreous body and globe
0.730 0.270 0.000
H49.9 Paralytic strabismus, unspecified
0.729 0.271 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.727 0.273 0.000
K75.8 Other specified inflammatory liver diseases
0.726 0.274 0.000
C04 Malignant neoplasm of floor of mouth
0.726 0.274 0.000
D61.0 Constitutional aplastic anaemia
0.723 0.277 0.000
D06.9 Cervix, unspecified
0.723 0.277 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.723 0.277 0.000
C69.3 Choroid
0.722 0.278 0.000
C81.7 Other Hodgkin's disease
0.722 0.278 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.722 0.278 0.000
E10.6 With other specified complications
0.721 0.279 0.000
C03 Malignant neoplasm of gum
0.719 0.281 0.000
E05.8 Other thyrotoxicosis
0.719 0.281 0.000
M34.0 Progressive systemic sclerosis
0.717 0.282 0.000
C95 Leukaemia of unspecified cell type
0.717 0.283 0.000
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C83.6 Undifferentiated (diffuse)
0.717 0.283 0.000
C83.5 Lymphoblastic (diffuse)
0.717 0.283 0.000
C83.4 Immunoblastic (diffuse)
0.717 0.283 0.000
C83.2 Mixed small and large cell (diffuse)
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
C85.0 Lymphosarcoma
0.717 0.283 0.000
C82.6 Cutaneous follicle centre lymphoma
0.717 0.283 0.000
C82.5 Diffuse follicle centre lymphoma
0.717 0.283 0.000
N05.1 Focal and segmental glomerular lesions
0.717 0.283 0.000
L58 Radiodermatitis
0.716 0.284 0.000
L55 Sunburn
0.716 0.284 0.000
L57.5 Actinic granuloma
0.716 0.284 0.000
L57.3 Poikiloderma of Civatte
0.716 0.284 0.000
L57.2 Cutis rhomboidalis nuchae
0.716 0.284 0.000
L57.1 Actinic reticuloid
0.716 0.284 0.000
D64.4 Congenital dyserythropoietic anaemia
0.716 0.284 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.716 0.284 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.716 0.284 0.000
N05.9 Unspecified
0.715 0.285 0.000
K90.3 Pancreatic steatorrhoea
0.714 0.286 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.714 0.286 0.000
K90.1 Tropical sprue
0.714 0.286 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.704 0.286 0.009
N04.1 Focal and segmental glomerular lesions
0.714 0.286 0.000
E14.7 With multiple complications
0.713 0.286 0.000
E14.0 With coma
0.713 0.286 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.713 0.287 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.713 0.287 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.712 0.288 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.712 0.288 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.711 0.289 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.711 0.289 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.711 0.289 0.000
L13 Other bullous disorders
0.710 0.290 0.000
D67 Hereditary factor IX deficiency
0.710 0.290 0.000
C83.0 Small cell (diffuse)
0.709 0.291 0.000
H51 Other disorders of binocular movement
0.708 0.291 0.000
M24.2 Disorder of ligament
0.708 0.292 0.000
H40.9 Glaucoma, unspecified
0.708 0.292 0.000
L44 Other papulosquamous disorders
0.705 0.292 0.003
L41 Parapsoriasis
0.705 0.292 0.003
L45 Papulosquamous disorders in diseases classified elsewhere
0.705 0.292 0.003
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.708 0.292 0.000
C81.3 Lymphocytic depletion
0.708 0.292 0.000
M35.2 Behcet's disease
0.708 0.292 0.000
M24.9 Joint derangement, unspecified
0.707 0.293 0.000
D55-D59 Haemolytic anaemias
0.707 0.293 0.000
D69.9 Haemorrhagic condition, unspecified
0.705 0.295 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.705 0.295 0.000
E25 Adrenogenital disorders
0.705 0.295 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.705 0.295 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.704 0.296 0.000
E32 Diseases of thymus
0.704 0.296 0.000
E30 Disorders of puberty, not elsewhere classified
0.704 0.296 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.704 0.296 0.000
C07 Malignant neoplasm of parotid gland
0.703 0.297 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.701 0.298 0.000
C70 Malignant neoplasm of meninges
0.701 0.299 0.000
L43.3 Subacute (active) lichen planus
0.700 0.299 0.001
L43.2 Lichenoid drug reaction
0.700 0.299 0.001
L43.1 Bullous lichen planus
0.700 0.299 0.001
L43.0 Hypertrophic lichen planus
0.700 0.299 0.001
C82.3 Follicular lymphoma grade IIIa
0.701 0.299 0.000
C84.5 Other and unspecified T-cell lymphomas
0.699 0.301 0.000
Q60-Q64 Congenital malformations of the urinary system
0.699 0.301 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.698 0.302 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.698 0.302 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.697 0.303 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.691 0.305 0.004
D00.1 Oesophagus
0.695 0.305 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.694 0.306 0.000
K73 Chronic hepatitis, not elsewhere classified
0.693 0.307 0.000
C93 Monocytic leukaemia
0.693 0.307 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.693 0.307 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.691 0.309 0.000
D04.3 Skin of other and unspecified parts of face
0.691 0.309 0.000
C10 Malignant neoplasm of oropharynx
0.691 0.309 0.000
H34 Retinal vascular occlusions
0.689 0.311 0.000
L94.3 Sclerodactyly
0.689 0.311 0.000
H49.8 Other paralytic strabismus
0.688 0.312 0.000
K51.8 Other ulcerative colitis
0.687 0.313 0.000
D04.9 Skin, unspecified
0.686 0.314 0.000
L94.2 Calcinosis cutis
0.685 0.315 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.685 0.315 0.000
E29 Testicular dysfunction
0.684 0.316 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.683 0.317 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.682 0.318 0.000
H06.2 Dysthyroid exophthalmos
0.682 0.318 0.001
D04.8 Skin of other sites
0.682 0.318 0.000
D04.0 Skin of lip
0.682 0.318 0.000
N04.2 Diffuse membranous glomerulonephritis
0.682 0.318 0.000
H49.2 Sixth [abducent] nerve palsy
0.681 0.319 0.000
E22.1 Hyperprolactinaemia
0.680 0.320 0.000
E28.9 Ovarian dysfunction, unspecified
0.679 0.321 0.000
E28.8 Other ovarian dysfunction
0.679 0.321 0.000
E28.1 Androgen excess
0.679 0.321 0.000
E28.0 Oestrogen excess
0.679 0.321 0.000
C86 Other specified types of T/NK-cell lymphoma
0.679 0.321 0.000
H55-H59 Other disorders of eye and adnexa
0.679 0.321 0.000
E27.9 Disorder of adrenal gland, unspecified
0.679 0.321 0.000
M24.6 Ankylosis of joint
0.678 0.322 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.677 0.323 0.000
M30 Polyarteritis nodosa and related conditions
0.676 0.323 0.000
D61.8 Other specified aplastic anaemias
0.676 0.324 0.000
D61.3 Idiopathic aplastic anaemia
0.676 0.324 0.000
D61.2 Aplastic anaemia due to other external agents
0.676 0.324 0.000
C02.9 Tongue, unspecified
0.675 0.325 0.000
Chapter XIV Diseases of the genitourinary system
0.675 0.325 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.673 0.327 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.673 0.327 0.000
M35.5 Multifocal fibrosclerosis
0.673 0.327 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.673 0.327 0.000
E27.2 Addisonian crisis
0.673 0.327 0.000
E07.8 Other specified disorders of thyroid
0.673 0.327 0.000
E07.1 Dyshormogenetic goitre
0.671 0.329 0.000
E07.0 Hypersecretion of calcitonin
0.671 0.329 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.670 0.330 0.000
M32 Systemic lupus erythematosus
0.669 0.330 0.000
C92 Myeloid leukaemia
0.669 0.331 0.000
E15 Nondiabetic hypoglycaemic coma
0.669 0.331 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.667 0.333 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.667 0.333 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.665 0.335 0.000
D73 Diseases of spleen
0.664 0.336 0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.664 0.336 0.000
E20.9 Hypoparathyroidism, unspecified
0.663 0.337 0.000
L12.1 Cicatricial pemphigoid
0.662 0.338 0.000
L93 Lupus erythematosus
0.658 0.342 0.000
E27.5 Adrenomedullary hyperfunction
0.658 0.342 0.000
E27.0 Other adrenocortical overactivity
0.658 0.342 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.657 0.343 0.000
L94.9 Localised connective tissue disorder, unspecified
0.657 0.343 0.000
D04.1 Skin of eyelid, including canthus
0.657 0.343 0.000
H40.3 Glaucoma secondary to eye trauma
0.657 0.343 0.000
D03.4 Melanoma in situ of scalp and neck
0.655 0.345 0.000
M24.56 Contracture of joint (Lower leg)
0.655 0.345 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.655 0.345 0.000
E24 Cushing's syndrome
0.653 0.347 0.000
K75.9 Inflammatory liver disease, unspecified
0.651 0.349 0.000
C02.1 Border of tongue
0.651 0.349 0.000
M15.0 Primary generalised (osteo)arthrosis
0.651 0.349 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.651 0.349 0.000
Q61 Cystic kidney disease
0.649 0.351 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.645 0.355 0.000
L08 Other local infections of skin and subcutaneous tissue
0.644 0.356 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.644 0.356 0.000
M15.4 Erosive (osteo)arthrosis
0.642 0.358 0.000
H43 Disorders of vitreous body
0.641 0.359 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.640 0.360 0.000
L10 Pemphigus
0.639 0.361 0.000
D68.2 Hereditary deficiency of other clotting factors
0.638 0.362 0.000
H42 Glaucoma in diseases classified elsewhere
0.636 0.364 0.000
C81.2 Mixed cellularity
0.635 0.365 0.000
L14 Bullous disorders in diseases classified elsewhere
0.634 0.365 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.634 0.366 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.634 0.366 0.000
E16.4 Abnormal secretion of gastrin
0.634 0.366 0.000
E16.3 Increased secretion of glucagon
0.634 0.366 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.633 0.367 0.000
L12.0 Bullous pemphigoid
0.631 0.369 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.631 0.369 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.631 0.369 0.000
M24.18 Other articular cartilage disorders (Other)
0.631 0.369 0.000
M24.14 Other articular cartilage disorders (Hand)
0.631 0.369 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.631 0.369 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.631 0.369 0.000
N03.8 Other
0.630 0.370 0.000
L03 Cellulitis
0.630 0.370 0.000
D04.6 Skin of upper limb, including shoulder
0.629 0.371 0.000
L95.8 Other vasculitis limited to skin
0.629 0.371 0.000
L40.0 Psoriasis vulgaris
0.021 0.372 0.608
K72 Hepatic failure, not elsewhere classified
0.628 0.372 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.627 0.373 0.000
M60 Myositis
0.627 0.373 0.000
H40.4 Glaucoma secondary to eye inflammation
0.627 0.373 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.627 0.373 0.000
L03.0 Cellulitis of finger and toe
0.626 0.374 0.000
D03.5 Melanoma in situ of trunk
0.625 0.375 0.000
C69.9 Eye, unspecified
0.625 0.375 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.624 0.376 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.624 0.376 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.624 0.376 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.624 0.376 0.000
M24.06 Loose body in joint-Lower leg
0.624 0.376 0.000
D75 Other diseases of blood and blood-forming organs
0.623 0.377 0.000
C00 Malignant neoplasm of lip
0.622 0.378 0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.621 0.378 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.620 0.380 0.000
E11 Non-insulin-dependent diabetes mellitus
0.620 0.380 0.000
C91 Lymphoid leukaemia
0.620 0.380 0.000
L12.9 Pemphigoid, unspecified
0.619 0.381 0.000
L94.8 Other specified localised connective tissue disorders
0.618 0.382 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.618 0.382 0.000
L87 Transepidermal elimination disorders
0.618 0.382 0.000
L86 Keratoderma in diseases classified elsewhere
0.618 0.382 0.000
Q43 Other congenital malformations of intestine
0.617 0.383 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.617 0.383 0.000
E06.4 Drug-induced thyroiditis
0.616 0.384 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.616 0.384 0.000
E06.1 Subacute thyroiditis
0.616 0.384 0.000
E06.0 Acute thyroiditis
0.616 0.384 0.000
E23 Hypofunction and other disorders of pituitary gland
0.615 0.385 0.000
E03.1 Congenital hypothyroidism without goitre
0.615 0.385 0.000
E31.0 Autoimmune polyglandular failure
0.615 0.385 0.000
H30.9 Chorioretinal inflammation, unspecified
0.615 0.385 0.000
E10.8 With unspecified complications
0.615 0.385 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.614 0.385 0.000
M24.03 Loose body in joint (Forearm)
0.613 0.387 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.613 0.387 0.000
C69.0 Conjunctiva
0.613 0.387 0.000
N04.0 Minor glomerular abnormality
0.612 0.388 0.000
E16.1 Other hypoglycaemia
0.612 0.388 0.000
C69.6 Orbit
0.611 0.389 0.000
N10-N16 Renal tubulo-interstitial diseases
0.611 0.389 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.609 0.391 0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.607 0.393 0.000
E06.5 Other chronic thyroiditis
0.604 0.395 0.000
H49.4 Progressive external ophthalmoplegia
0.603 0.397 0.000
M24.26 Disorder of ligament (Lower leg)
0.602 0.398 0.000
D73.5 Infarction of spleen
0.602 0.398 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.601 0.399 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.600 0.399 0.000
C43.8 Overlapping malignant melanoma of skin
0.600 0.400 0.000
C43.0 Malignant melanoma of lip
0.600 0.400 0.000
C02.2 Ventral surface of tongue
0.600 0.400 0.000
C70.0 Cerebral meninges
0.600 0.400 0.000
M62 Other disorders of muscle
0.597 0.403 0.000
M15.8 Other polyarthrosis
0.597 0.403 0.000
N10 Acute tubulo-interstitial nephritis
0.597 0.403 0.000
D56 Thalassaemia
0.597 0.403 0.000
L94.6 Ainhum
0.596 0.404 0.000
L94.5 Poikiloderma vasculare atrophicans
0.596 0.404 0.000
L94.4 Gottron's papules
0.596 0.404 0.000
L94.1 Linear scleroderma
0.596 0.404 0.000
E14.6 With other specified complications
0.596 0.404 0.000
D09 Carcinoma in situ of other and unspecified sites
0.595 0.404 0.000
D84 Other immunodeficiencies
0.595 0.405 0.000
H49.3 Total (external) ophthalmoplegia
0.594 0.406 0.000
E13 Other specified diabetes mellitus
0.594 0.406 0.000
C84.4 Peripheral T-cell lymphoma
0.592 0.408 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.590 0.410 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.590 0.410 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.590 0.410 0.000
C84.3 Lymphoepithelioid lymphoma
0.590 0.410 0.000
C84.2 T-zone lymphoma
0.590 0.410 0.000
C84.1 Sezary's diease
0.590 0.410 0.000
L88 Pyoderma gangrenosum
0.589 0.411 0.000
C04.0 Anterior floor of mouth
0.589 0.411 0.000
D68.1 Hereditary factor XI deficiency
0.588 0.411 0.000
N03.1 Focal and segmental glomerular lesions
0.588 0.412 0.000
Q61.3 Polycystic kidney, unspecified
0.588 0.412 0.000
M35.1 Other overlap syndromes
0.587 0.413 0.000
N00 Acute nephritic syndrome
0.587 0.413 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.586 0.414 0.000
D73.0 Hyposplenism
0.586 0.414 0.000
K77 Liver disorders in diseases classified elsewhere
0.586 0.414 0.000
C84.0 Mycosis fungoides
0.585 0.414 0.000
L13.0 Dermatitis herpetiformis
0.585 0.415 0.000
C03.1 Lower gum
0.585 0.415 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.585 0.415 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.585 0.415 0.000
H43.8 Other disorders of vitreous body
0.585 0.415 0.000
C12 Malignant neoplasm of pyriform sinus
0.583 0.417 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.583 0.417 0.000
N06 Isolated proteinuria with specified morphological lesion
0.583 0.417 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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