TreeWAS – Variant ID: rs45585732

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
M45 Ankylosing spondylitis	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
M45-M49 Spondylopathies	1.000	0.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
Chapter I Certain infectious and parasitic diseases	0.997	0.003	0.000
E03 Other hypothyroidism	0.000	0.008	0.992
E00-E07 Disorders of thyroid gland	0.000	0.014	0.986
Chapter V Mental and behavioural disorders	0.985	0.015	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.981	0.019	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.980	0.020	0.000
O60-O75 Complications of labour and delivery	0.978	0.022	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.978	0.022	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.001	0.032	0.967
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.967	0.033	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.957	0.043	0.000
E10-E14 Diabetes mellitus	0.000	0.045	0.955
E10 Insulin-dependent diabetes mellitus	0.000	0.045	0.955
M06.0 Seronegative rheumatoid arthritis	0.953	0.047	0.000
E10.9 Without complications	0.000	0.049	0.951
O20-O29 Other maternal disorders predominantly related to pregnancy	0.949	0.051	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.948	0.052	0.000
B95-B98 Bacterial, viral and other infectious agents	0.943	0.057	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.938	0.062	0.000
O00-O08 Pregnancy with abortive outcome	0.933	0.067	0.000
O63 Long labour	0.930	0.070	0.000
L40-L45 Papulosquamous disorders	0.928	0.072	0.000
M20-M25 Other joint disorders	0.922	0.078	0.000
M07 Psoriatic and enteropathic arthropathies	0.920	0.080	0.000
B25-B34 Other viral diseases	0.916	0.084	0.000
O63.1 Prolonged second stage (of labour)	0.904	0.096	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.900	0.100	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.898	0.102	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.897	0.103	0.000
F10.0 Acute intoxication	0.896	0.104	0.000
L03 Cellulitis	0.892	0.108	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.891	0.109	0.000
O80-O84 Delivery	0.885	0.115	0.000
F30-F39 Mood [affective] disorders	0.885	0.115	0.000
L40 Psoriasis	0.880	0.120	0.000
M05 Seropositive rheumatoid arthritis	0.875	0.125	0.000
O26.8 Other specified pregnancy-related conditions	0.872	0.128	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.870	0.130	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.868	0.132	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.867	0.133	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.867	0.133	0.000
L40.5 Arthropathic psoriasis	0.864	0.136	0.000
F10.1 Harmful use	0.864	0.136	0.000
M07.3 Other psoriatic arthropathies	0.862	0.138	0.000
F31 Bipolar affective disorder	0.861	0.139	0.000
B34 Viral infection of unspecified site	0.860	0.140	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.855	0.145	0.000
M06.4 Inflammatory polyarthropathy	0.851	0.149	0.000
O04 Medical abortion	0.849	0.151	0.000
O30 Multiple gestation	0.849	0.151	0.000
M20 Acquired deformities of fingers and toes	0.848	0.152	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.843	0.157	0.000
Chapter VII Diseases of the eye and adnexa	0.841	0.159	0.000
E10.3 With ophthalmic complications	0.000	0.161	0.839
E50-E64 Other nutritional deficiencies	0.000	0.162	0.837
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.165	0.835
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.835	0.165	0.000
H20 Iridocyclitis	0.834	0.166	0.000
B99-B99 Other infectious diseases	0.833	0.167	0.000
E07 Other disorders of thyroid	0.000	0.169	0.831
H20.9 Iridocyclitis, unspecified	0.830	0.170	0.000
O73 Retained placenta and membranes, without haemorrhage	0.829	0.171	0.000
F80-F89 Disorders of psychological development	0.826	0.174	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.824	0.176	0.000
A00-A09 Intestinal infectious diseases	0.819	0.181	0.000
O42 Premature rupture of membranes	0.819	0.181	0.000
M25 Other joint disorders, not elsewhere classified	0.818	0.182	0.000
M24 Other specific joint derangements	0.815	0.185	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.814	0.186	0.000
B34.9 Viral infection, unspecified	0.814	0.186	0.000
M13 Other arthritis	0.813	0.187	0.000
M25.4 Effusion of joint	0.811	0.189	0.000
Chapter XXII Codes for special purposes	0.811	0.189	0.000
S80-S89 Injuries to the knee and lower leg	0.811	0.189	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.806	0.194	0.000
M25.46 Effusion of joint (Lower leg)	0.806	0.194	0.000
L03.0 Cellulitis of finger and toe	0.805	0.195	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.801	0.199	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.799	0.201	0.000
O75.0 Maternal distress during labour and delivery	0.799	0.201	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.799	0.201	0.000
O40 Polyhydramnios	0.795	0.205	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.794	0.206	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.792	0.208	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.785	0.215	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.001	0.217	0.782
O65 Obstructed labour due to maternal pelvic abnormality	0.783	0.217	0.000
M86-M90 Other osteopathies	0.783	0.217	0.000
E10.4 With neurological complications	0.000	0.218	0.782
B20-B24 Human immunodeficiency virus [HIV] disease	0.780	0.220	0.000
F10.2 Dependence syndrome	0.780	0.220	0.000
S82 Fracture of lower leg, including ankle	0.779	0.221	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.779	0.221	0.000
M00-M03 Infectious arthropathies	0.779	0.221	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.777	0.223	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.776	0.224	0.000
A30-A49 Other bacterial diseases	0.776	0.224	0.000
F60-F69 Disorders of adult personality and behaviour	0.768	0.231	0.000
O32.0 Maternal care for unstable lie	0.768	0.232	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.768	0.232	0.000
M21 Other acquired deformities of limbs	0.768	0.232	0.000
O04.9 Complete or unspecified, without complication	0.768	0.232	0.000
F29 Unspecified nonorganic psychosis	0.767	0.233	0.000
E06 Thyroiditis	0.000	0.233	0.767
M20.6 Acquired deformity of toe(s), unspecified	0.766	0.234	0.000
O30.0 Twin pregnancy	0.764	0.236	0.000
L03.9 Cellulitis, unspecified	0.762	0.238	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.762	0.238	0.000
O02 Other abnormal products of conception	0.760	0.240	0.000
L50-L54 Urticaria and erythema	0.758	0.241	0.000
O43 Placental disorders	0.756	0.244	0.000
O21 Excessive vomiting in pregnancy	0.753	0.247	0.000
M11 Other crystal arthropathies	0.753	0.247	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.752	0.248	0.000
S82.6 Fracture of lateral malleolus	0.751	0.249	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.251	0.749
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.749	0.251	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.743	0.256	0.000
M20.5 Other deformities of toe(s) (acquired)	0.742	0.258	0.000
O75.8 Other specified complications of labour and delivery	0.741	0.259	0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.741	0.259	0.000
E04 Other non-toxic goitre	0.000	0.259	0.741
M06.3 Rheumatoid nodule	0.740	0.260	0.000
A80-A89 Viral infections of the central nervous system	0.739	0.261	0.000
L05 Pilonidal cyst	0.739	0.261	0.000
M65-M68 Disorders of synovium and tendon	0.736	0.264	0.000
F10.4 Withdrawal state with delirium	0.735	0.265	0.000
L03.3 Cellulitis of trunk	0.734	0.266	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.734	0.266	0.000
M20.3 Other deformity of hallux (acquired)	0.733	0.267	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.733	0.267	0.000
F31.9 Bipolar affective disorder, unspecified	0.732	0.268	0.000
B35-B49 Mycoses	0.731	0.269	0.000
S82.60 Fracture of lateral malleolus (closed)	0.730	0.270	0.000
O03 Spontaneous abortion	0.730	0.270	0.000
O41 Other disorders of amniotic fluid and membranes	0.730	0.270	0.000
L43 Lichen planus	0.729	0.271	0.000
O82 Single delivery by Caesarean section	0.729	0.271	0.000
F10.3 Withdrawal state	0.727	0.273	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.278	0.722
O73.0 Retained placenta, without haemorrhage	0.722	0.278	0.000
O47 False labour	0.721	0.279	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.721	0.279	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.281	0.719
O69 Labour and delivery complicated by umbilical cord complications	0.718	0.282	0.000
L03.2 Cellulitis of face	0.717	0.283	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M14 Arthropathies in other diseases classified elsewhere	0.717	0.283	0.000
M12 Other specific arthropathies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
M60-M63 Disorders of muscles	0.717	0.283	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.717	0.283	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.717	0.283	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.717	0.283	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.717	0.283	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.717	0.283	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.717	0.283	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
M49 Spondylopathies in diseases classified elsewhere	0.717	0.283	0.000
O85-O92 Complications predominantly related to the puerperium	0.715	0.285	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.715	0.285	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.715	0.285	0.000
B65-B83 Helminthiases	0.715	0.285	0.000
B50-B64 Protozoal diseases	0.715	0.285	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.715	0.285	0.000
A75-A79 Rickettsioses	0.715	0.285	0.000
A70-A74 Other diseases caused by chlamydiae	0.715	0.285	0.000
A65-A69 Other spirochaetal diseases	0.715	0.285	0.000
A20-A28 Certain zoonotic bacterial diseases	0.715	0.285	0.000
A15-A19 Tuberculosis	0.715	0.285	0.000
B99 Other and unspecified infectious diseases	0.715	0.285	0.000
F81 Specific developmental disorders of scholastic skills	0.713	0.287	0.000
E03.8 Other specified hypothyroidism	0.000	0.289	0.711
E03.5 Myxoedema coma	0.000	0.289	0.711
E03.4 Atrophy of thyroid (acquired)	0.000	0.289	0.711
E03.3 Postinfectious hypothyroidism	0.000	0.289	0.711
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.289	0.711
E03.1 Congenital hypothyroidism without goitre	0.000	0.289	0.711
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.289	0.711
F31.0 Bipolar affective disorder, current episode hypomanic	0.710	0.290	0.000
O32.2 Maternal care for transverse and oblique lie	0.709	0.291	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.709	0.291	0.000
O32.8 Maternal care for other malpresentation of foetus	0.708	0.292	0.000
O20 Haemorrhage in early pregnancy	0.708	0.292	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.293	0.707
E00 Congenital iodine-deficiency syndrome	0.000	0.293	0.707
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.293	0.707
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.706	0.294	0.000
F70-F79 Mental retardation	0.706	0.294	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.706	0.294	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.704	0.296	0.000
O80 Single spontaneous delivery	0.703	0.297	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.703	0.297	0.000
O81 Single delivery by forceps and vacuum extractor	0.702	0.297	0.000
L10-L14 Bullous disorders	0.702	0.298	0.000
O74 Complications of anaesthesia during labour and delivery	0.701	0.299	0.000
O71 Other obstetric trauma	0.701	0.299	0.000
O60 Preterm delivery	0.701	0.299	0.000
O23 Infections of genito-urinary tract in pregnancy	0.701	0.299	0.000
F99-F99 Unspecified mental disorder	0.698	0.302	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.696	0.304	0.000
O45 Premature separation of placenta [abruptio placentae]	0.693	0.307	0.000
O33 Maternal care for known or suspected disproportion	0.693	0.307	0.000
O31 Complications specific to multiple gestation	0.693	0.307	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.693	0.307	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.693	0.307	0.000
B15-B19 Viral hepatitis	0.692	0.308	0.000
O72 Postpartum haemorrhage	0.691	0.308	0.000
M91-M94 Chondropathies	0.690	0.310	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.689	0.311	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.689	0.311	0.000
S70-S79 Injuries to the hip and thigh	0.688	0.312	0.000
O63.9 Long labour, unspecified	0.687	0.313	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.686	0.314	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.686	0.314	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.686	0.314	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.686	0.314	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.686	0.314	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.686	0.314	0.000
F11 Mental and behavioural disorders due to use of opioids	0.686	0.314	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.685	0.315	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.315	0.684
E10.8 With unspecified complications	0.000	0.315	0.684
E10.7 With multiple complications	0.000	0.315	0.684
E10.6 With other specified complications	0.000	0.315	0.684
E10.2 With renal complications	0.000	0.315	0.684
E10.1 With ketoacidosis	0.000	0.315	0.684
E10.0 With coma	0.000	0.315	0.684
E40-E46 Malnutrition	0.001	0.316	0.684
M06.08 Seronegative rheumatoid arthritis (Other)	0.683	0.317	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.683	0.317	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.683	0.317	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.683	0.317	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.683	0.317	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.683	0.317	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.683	0.317	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.683	0.317	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.683	0.317	0.000
O32.1 Maternal care for breech presentation	0.683	0.317	0.000
O44 Placenta praevia	0.683	0.317	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.681	0.318	0.000
O70 Perineal laceration during delivery	0.681	0.319	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.681	0.319	0.000
M40-M43 Deforming dorsopathies	0.680	0.319	0.000
O29 Complications of anaesthesia during pregnancy	0.680	0.320	0.000
O28 Abnormal findings on antenatal screening of mother	0.680	0.320	0.000
O22 Venous complications in pregnancy	0.680	0.320	0.000
O25 Malnutrition in pregnancy	0.680	0.320	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.680	0.320	0.000
F10.9 Unspecified mental and behavioural disorder	0.680	0.320	0.000
F10.8 Other mental and behavioural disorders	0.680	0.320	0.000
F10.7 Residual and late-onset psychotic disorder	0.680	0.320	0.000
F10.6 Amnesic syndrome	0.680	0.320	0.000
F10.5 Psychotic disorder	0.680	0.320	0.000
H20.1 Chronic iridocyclitis	0.677	0.323	0.000
O66 Other obstructed labour	0.675	0.325	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.675	0.325	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.673	0.327	0.000
L04 Acute lymphadenitis	0.673	0.327	0.000
L01 Impetigo	0.673	0.327	0.000
L00 Staphylococcal scalded skin syndrome	0.673	0.327	0.000
L20-L30 Dermatitis and eczema	0.672	0.328	0.000
H40-H42 Glaucoma	0.671	0.329	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.670	0.330	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.670	0.330	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.669	0.331	0.000
O07 Failed attempted abortion	0.669	0.331	0.000
O06 Unspecified abortion	0.669	0.331	0.000
O05 Other abortion	0.669	0.331	0.000
O01 Hydatidiform mole	0.669	0.331	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.669	0.331	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.669	0.331	0.000
O04.4 Incomplete, without complication	0.668	0.332	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.668	0.332	0.000
E61 Deficiency of other nutrient elements	0.000	0.332	0.667
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.668	0.332	0.000
E53 Deficiency of other B group vitamins	0.000	0.332	0.667
O63.2 Delayed delivery of second twin, triplet, etc.	0.667	0.333	0.000
L44 Other papulosquamous disorders	0.665	0.334	0.000
L41 Parapsoriasis	0.665	0.334	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.665	0.334	0.000
L42 Pityriasis rosea	0.665	0.334	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.666	0.334	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.663	0.337	0.000
E10.5 With peripheral circulatory complications	0.000	0.337	0.663
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.663	0.337	0.000
H20.0 Acute and subacute iridocyclitis	0.662	0.338	0.000
F20 Schizophrenia	0.662	0.338	0.000
O61 Failed induction of labour	0.662	0.338	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.662	0.338	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.661	0.339	0.000
M33 Dermatopolymyositis	0.661	0.339	0.000
M32 Systemic lupus erythematosus	0.661	0.339	0.000
M30 Polyarteritis nodosa and related conditions	0.661	0.339	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.661	0.339	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.661	0.339	0.000
S82.4 Fracture of fibula alone	0.660	0.340	0.000
M07.6 Other enteropathic arthropathies	0.659	0.341	0.000
M07.5 Arthropathy in ulcerative colitis	0.659	0.341	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.659	0.341	0.000
M07.2 Psoriatic spondylitis	0.659	0.341	0.000
M07.1 Arthritis mutilans	0.659	0.341	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.659	0.341	0.000
L08 Other local infections of skin and subcutaneous tissue	0.659	0.341	0.000
A46 Erysipelas	0.659	0.341	0.000
E55 Vitamin D deficiency	0.000	0.343	0.657
B33 Other viral diseases, not elsewhere classified	0.657	0.343	0.000
B30 Viral conjunctivitis	0.657	0.343	0.000
B27 Infectious mononucleosis	0.657	0.343	0.000
B26 Mumps	0.657	0.343	0.000
F30 Manic episode	0.654	0.346	0.000
L40.0 Psoriasis vulgaris	0.652	0.348	0.000
M34 Systemic sclerosis	0.651	0.349	0.000
B34.8 Other viral infections of unspecified site	0.651	0.349	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.350	0.650
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.649	0.350	0.000
A04 Other bacterial intestinal infections	0.648	0.351	0.000
M47 Spondylosis	0.648	0.352	0.000
M13.9 Arthritis, unspecified	0.648	0.352	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.647	0.353	0.000
O02.1 Missed abortion	0.646	0.354	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.645	0.355	0.000
O32.6 Maternal care for compound presentation	0.645	0.355	0.000
O32.4 Maternal care for high head at term	0.645	0.355	0.000
O32.3 Maternal care for face, brow and chin presentation	0.645	0.355	0.000
B25 Cytomegaloviral disease	0.645	0.355	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.644	0.356	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.644	0.356	0.000
O26.5 Maternal hypotension syndrome	0.644	0.356	0.000
O26.4 Herpes gestationis	0.644	0.356	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.644	0.356	0.000
O26.2 Pregnancy care of habitual aborter	0.644	0.356	0.000
O26.1 Low weight gain in pregnancy	0.644	0.356	0.000
O26.0 Excessive weight gain in pregnancy	0.644	0.356	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.356	0.643
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.643	0.357	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.641	0.359	0.000
O82.0 Delivery by elective Caesarean section	0.641	0.359	0.000
M24.0 Loose body in joint	0.641	0.359	0.000
O00 Ectopic pregnancy	0.641	0.359	0.000
Q18 Other congenital malformations of face and neck	0.639	0.361	0.000
O75.9 Complication of labour and delivery, unspecified	0.639	0.361	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.639	0.361	0.000
O75.4 Other complications of obstetric surgery and procedures	0.639	0.361	0.000
O75.3 Other infection during labour	0.639	0.361	0.000
O75.1 Shock during or following labour and delivery	0.639	0.361	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.639	0.361	0.000
M25.47 Effusion of joint (Ankle and foot)	0.636	0.364	0.000
O42.9 Premature rupture of membranes, unspecified	0.636	0.364	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.365	0.635
O94-O99 Other obstetric conditions, not elsewhere classified	0.635	0.365	0.000
O84 Multiple delivery	0.634	0.365	0.000
O83 Other assisted single delivery	0.634	0.365	0.000
F38 Other mood [affective] disorders	0.634	0.366	0.000
F34 Persistent mood [affective] disorders	0.634	0.366	0.000
F39 Unspecified mood [affective] disorder	0.634	0.366	0.000
E13 Other specified diabetes mellitus	0.000	0.366	0.634
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.634	0.366	0.000
Q60-Q64 Congenital malformations of the urinary system	0.632	0.368	0.000
M46 Other inflammatory spondylopathies	0.632	0.368	0.000
S82.2 Fracture of shaft of tibia	0.632	0.368	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.632	0.368	0.000
M88 Paget's disease of bone [osteitis deformans]	0.631	0.369	0.000
L40.8 Other psoriasis	0.631	0.369	0.000
L40.4 Guttate psoriasis	0.631	0.369	0.000
L40.3 Pustulosis palmaris et plantaris	0.631	0.369	0.000
L40.2 Acrodermatitis continua	0.631	0.369	0.000
L40.1 Generalised pustular psoriasis	0.631	0.369	0.000
M02 Reactive arthropathies	0.631	0.369	0.000
O03.4 Incomplete, without complication	0.630	0.370	0.000
M21.6 Other acquired deformities of ankle and foot	0.629	0.371	0.000
O43.1 Malformation of placenta	0.628	0.372	0.000
O24 Diabetes mellitus in pregnancy	0.627	0.372	0.000
M05.8 Other seropositive rheumatoid arthritis	0.627	0.373	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.627	0.373	0.000
M05.2 Rheumatoid vasculitis	0.627	0.373	0.000
M05.1 Rheumatoid lung disease	0.627	0.373	0.000
M05.0 Felty's syndrome	0.627	0.373	0.000
M13.0 Polyarthritis, unspecified	0.627	0.373	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.627	0.373	0.000
S86 Injury of muscle and tendon at lower leg level	0.625	0.375	0.000
B24 Unspecified human immunodeficiency virus [HIV] disease	0.625	0.375	0.000
O80.9 Single spontaneous delivery, unspecified	0.624	0.376	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.623	0.377	0.000
S10-S19 Injuries to the neck	0.623	0.377	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.623	0.377	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.623	0.377	0.000
M22 Disorders of patella	0.622	0.378	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.622	0.378	0.000
F25 Schizoaffective disorders	0.622	0.378	0.000
F23 Acute and transient psychotic disorders	0.622	0.378	0.000
F28 Other nonorganic psychotic disorders	0.622	0.378	0.000
F24 Induced delusional disorder	0.622	0.378	0.000
F21 Schizotypal disorder	0.622	0.378	0.000
F22 Persistent delusional disorders	0.619	0.381	0.000
S82.7 Multiple fractures of lower leg	0.619	0.381	0.000
M07.38 Other psoriatic arthropathies (Other)	0.618	0.382	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.618	0.382	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.618	0.382	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.618	0.382	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.618	0.382	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.618	0.382	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.618	0.382	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.618	0.382	0.000
L05.9 Pilonidal cyst without abscess	0.618	0.382	0.000
F31.8 Other bipolar affective disorders	0.618	0.382	0.000
F31.7 Bipolar affective disorder, currently in remission	0.618	0.382	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.618	0.382	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.618	0.382	0.000
B34.4 Papovirus infection, unspecified	0.617	0.383	0.000
B34.3 Parvovirus infection, unspecified	0.617	0.383	0.000
B34.2 Coronavirus infection, unspecified	0.617	0.383	0.000
B34.1 Enterovirus infection, unspecified	0.617	0.383	0.000
B34.0 Adenovirus infection, unspecified	0.617	0.383	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.616	0.383	0.000
L57.0 Actinic keratosis	0.615	0.385	0.000
F60 Specific personality disorders	0.614	0.386	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.613	0.387	0.000
Q35-Q37 Cleft lip and cleft palate	0.613	0.387	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.613	0.387	0.000
Q00-Q07 Congenital malformations of the nervous system	0.613	0.387	0.000
O62 Abnormalities of forces of labour	0.613	0.387	0.000
M20.0 Deformity of finger(s)	0.611	0.389	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.610	0.390	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.610	0.390	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.610	0.390	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.610	0.390	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.610	0.390	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.610	0.390	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.610	0.390	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.610	0.390	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.610	0.390	0.000
E06.3 Autoimmune thyroiditis	0.000	0.390	0.610
S70 Superficial injury of hip and thigh	0.609	0.391	0.000
L03.8 Cellulitis of other sites	0.609	0.391	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.609	0.391	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.608	0.391	0.000
O04.7 Complete or unspecified, complicated by embolism	0.608	0.391	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.608	0.391	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.608	0.391	0.000
O04.3 Incomplete, with other and unspecified complications	0.608	0.391	0.000
O04.2 Incomplete, complicated by embolism	0.608	0.391	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.608	0.391	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.608	0.391	0.000
O30.9 Multiple gestation, unspecified	0.608	0.391	0.000
O30.8 Other multiple gestation	0.608	0.391	0.000
O30.2 Quadruplet pregnancy	0.608	0.391	0.000
O30.1 Triplet pregnancy	0.608	0.391	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.392	0.608
O36 Maternal care for other known or suspected foetal problems	0.608	0.392	0.000
Q80-Q89 Other congenital malformations	0.607	0.393	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.605	0.395	0.000
B02 Zoster [herpes zoster]	0.605	0.395	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.605	0.395	0.000
T33-T35 Frostbite	0.604	0.396	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.604	0.396	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.604	0.396	0.000
T00-T07 Injuries involving multiple body regions	0.604	0.396	0.000
M24.1 Other articular cartilage disorders	0.602	0.397	0.000
B35 Dermatophytosis	0.602	0.398	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.399	0.600
E63 Other nutritional deficiencies	0.000	0.399	0.600
E56 Other vitamin deficiencies	0.000	0.399	0.600
E51 Thiamine deficiency	0.000	0.399	0.600
E50 Vitamin A deficiency	0.000	0.399	0.600
E60 Dietary zinc deficiency	0.000	0.399	0.600
E59 Dietary selenium deficiency	0.000	0.399	0.600
E58 Dietary calcium deficiency	0.000	0.399	0.600
E54 Ascorbic acid deficiency	0.000	0.399	0.600
E52 Niacin deficiency [pellagra]	0.000	0.399	0.600
Q12 Congenital lens malformations	0.600	0.399	0.000
H55-H59 Other disorders of eye and adnexa	0.600	0.400	0.000
E05.8 Other thyrotoxicosis	0.000	0.401	0.599
E05.5 Thyroid crisis or storm	0.000	0.401	0.599
E05.4 Thyrotoxicosis factitia	0.000	0.401	0.599
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.401	0.599
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.401	0.599
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.401	0.599
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.598	0.401	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.598	0.401	0.000
H17 Corneal scars and opacities	0.598	0.401	0.000
H15 Disorders of sclera	0.598	0.401	0.000
F33 Recurrent depressive disorder	0.599	0.401	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations