TreeWAS – Variant ID: rs4594074

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.032	0.968
Chapter XXI Factors influencing health status and contact with health services	0.029	0.971
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.029	0.971
Chapter II Neoplasms	0.027	0.973
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.027	0.973
Chapter VII Diseases of the eye and adnexa	0.026	0.974
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.026	0.974
Chapter X Diseases of the respiratory system	0.026	0.974
Chapter XIV Diseases of the genitourinary system	0.025	0.975
Chapter XI Diseases of the digestive system	0.025	0.975
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.025	0.975
Chapter IX Diseases of the circulatory system	0.024	0.976
Chapter XX External causes of morbidity and mortality	0.024	0.976
Chapter XV Pregnancy, childbirth and the puerperium	0.024	0.976
Chapter VI Diseases of the nervous system	0.023	0.977
Chapter XXII Codes for special purposes	0.023	0.977
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.023	0.977
Chapter XVI Certain conditions originating in the perinatal period	0.023	0.977
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.023	0.977
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.023	0.977
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.023	0.977
R50-R69 General symptoms and signs	0.023	0.977
Chapter I Certain infectious and parasitic diseases	0.023	0.977
Z86 Personal history of certain other diseases	0.023	0.977
Chapter XII Diseases of the skin and subcutaneous tissue	0.023	0.977
Chapter V Mental and behavioural disorders	0.022	0.978
Chapter IV Endocrine, nutritional and metabolic diseases	0.022	0.978
Chapter VIII Diseases of the ear and mastoid process	0.022	0.978
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.022	0.978
D10-D36 Benign neoplasms	0.022	0.978
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.021	0.979
Z40-Z54 Persons encountering health services for specific procedures and health care	0.021	0.979
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.021	0.979
Z90 Acquired absence of organs, not elsewhere classified	0.021	0.979
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.021	0.979
R47-R49 Symptoms and signs involving speech and voice	0.021	0.979
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.021	0.979
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.021	0.979
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.021	0.979
Z70-Z76 Persons encountering health services in other circumstances	0.021	0.979
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.021	0.979
R95-R99 Ill-defined and unknown causes of mortality	0.021	0.979
Z00-Z13 Persons encountering health services for examination and investigation	0.021	0.979
Z85 Personal history of malignant neoplasm	0.021	0.979
K55-K64 Other diseases of intestines	0.021	0.979
R30-R39 Symptoms and signs involving the urinary system	0.021	0.979
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.021	0.979
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.021	0.979
N30-N39 Other diseases of urinary system	0.020	0.980
Z92 Personal history of medical treatment	0.020	0.980
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.020	0.980
Z80 Family history of malignant neoplasm	0.020	0.980
C15-C26 Malignant neoplasms of digestive organs	0.020	0.980
Z96 Presence of other functional implants	0.020	0.980
M50-M54 Other dorsopathies	0.020	0.980
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.020	0.980
J40-J47 Chronic lower respiratory diseases	0.020	0.980
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.020	0.980
M20-M25 Other joint disorders	0.020	0.980
H25-H28 Disorders of lens	0.020	0.980
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.020	0.980
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.020	0.980
Z93 Artificial opening status	0.020	0.980
C64-C68 Malignant neoplasms of urinary tract	0.020	0.980
H30-H36 Disorders of choroid and retina	0.020	0.980
M45-M49 Spondylopathies	0.020	0.980
M05-M14 Inflammatory polyarthropathies	0.020	0.980
C51-C58 Malignant neoplasms of female genital organs	0.020	0.980
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.020	0.980
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.020	0.980
Z91 Personal history of risk-factors, not elsewhere classified	0.020	0.980
C60-C63 Malignant neoplasms of male genital organs	0.020	0.980
Z97 Presence of other devices	0.020	0.980
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.019	0.980
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.019	0.980
Z89 Acquired absence of limb	0.019	0.980
D00-D09 In situ neoplasms	0.019	0.980
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.019	0.980
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.019	0.980
Z87 Personal history of other diseases and conditions	0.019	0.980
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.019	0.980
C40-C41 Malignant neoplasms of bone and articular cartilage	0.019	0.980
Z84 Family history of other conditions	0.019	0.980
Z81 Family history of mental and behavioural disorders	0.019	0.980
H40-H42 Glaucoma	0.019	0.980
H53-H54 Visual disturbances and blindness	0.019	0.981
I10-I15 Hypertensive diseases	0.019	0.981
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.019	0.981
C50-C50 Malignant neoplasm of breast	0.019	0.981
N20-N23 Urolithiasis	0.019	0.981
H43-H45 Disorders of vitreous body and globe	0.019	0.981
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.019	0.981
Z83 Family history of other specific disorders	0.019	0.981
M86-M90 Other osteopathies	0.019	0.981
M40-M43 Deforming dorsopathies	0.019	0.981
D37-D48 Neoplasms of uncertain or unknown behaviour	0.019	0.981
H55-H59 Other disorders of eye and adnexa	0.019	0.981
H10-H13 Disorders of conjunctiva	0.019	0.981
H46-H48 Disorders of optic nerve and visual pathways	0.019	0.981
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.019	0.981
M91-M94 Chondropathies	0.019	0.981
M60-M63 Disorders of muscles	0.019	0.981
Z94 Transplanted organ and tissue status	0.019	0.981
M00-M03 Infectious arthropathies	0.019	0.981
M65-M68 Disorders of synovium and tendon	0.019	0.981
M15-M19 Arthrosis	0.019	0.981
N60-N64 Disorders of breast	0.019	0.981
Z95 Presence of cardiac and vascular implants and grafts	0.019	0.981
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.019	0.981
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.019	0.981
J30-J39 Other diseases of upper respiratory tract	0.019	0.981
J95-J99 Other diseases of the respiratory system	0.019	0.981
M80-M85 Disorders of bone density and structure	0.019	0.981
M70-M79 Other soft tissue disorders	0.019	0.981
J20-J22 Other acute lower respiratory infections	0.019	0.981
J00-J06 Acute upper respiratory infections	0.019	0.981
N80-N98 Noninflammatory disorders of female genital tract	0.019	0.981
Z86.4 Personal history of psychoactive substance abuse	0.019	0.981
K20-K31 Diseases of oesophagus, stomach and duodenum	0.019	0.981
Z98 Other postsurgical states	0.019	0.981
J90-J94 Other diseases of pleura	0.019	0.981
J80-J84 Other respiratory diseases principally affecting the interstitium	0.019	0.981
N25-N29 Other disorders of kidney and ureter	0.019	0.981
J60-J70 Lung diseases due to external agents	0.019	0.981
N00-N08 Glomerular diseases	0.019	0.981
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.018	0.981
Z86.7 Personal history of diseases of the circulatory system	0.019	0.981
R07 Pain in throat and chest	0.018	0.981
N40-N51 Diseases of male genital organs	0.018	0.981
T36-T50 Poisoning by drugs, medicaments and biological substances	0.018	0.981
S80-S89 Injuries to the knee and lower leg	0.018	0.981
C43-C44 Melanoma and other malignant neoplasms of skin	0.018	0.981
I60-I69 Cerebrovascular diseases	0.018	0.981
S00-S09 Injuries to the head	0.018	0.982
R19 Other symptoms and signs involving the digestive system and abdomen	0.018	0.982
S50-S59 Injuries to the elbow and forearm	0.018	0.982
J09-J18 Influenza and pneumonia	0.018	0.982
R11 Nausea and vomiting	0.018	0.982
K35-K38 Diseases of appendix	0.018	0.982
N17-N19 Renal failure	0.018	0.982
N99-N99 Other disorders of the genitourinary system	0.018	0.982
S40-S49 Injuries to the shoulder and upper arm	0.018	0.982
N10-N16 Renal tubulo-interstitial diseases	0.018	0.982
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.018	0.982
S20-S29 Injuries to the thorax	0.018	0.982
S70-S79 Injuries to the hip and thigh	0.018	0.982
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.018	0.982
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.018	0.982
T66-T78 Other and unspecified effects of external causes	0.018	0.982
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.018	0.982
T15-T19 Effects of foreign body entering through natural orifice	0.018	0.982
T20-T25 Burns and corrosions of external body surface, specified by site	0.018	0.982
S10-S19 Injuries to the neck	0.018	0.982
T79-T79 Certain early complications of trauma	0.018	0.982
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.018	0.982
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.018	0.982
T00-T07 Injuries involving multiple body regions	0.018	0.982
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.018	0.982
K90-K93 Other diseases of the digestive system	0.018	0.982
T33-T35 Frostbite	0.018	0.982
T26-T28 Burns and corrosions confined to eye and internal organs	0.018	0.982
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.018	0.982
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.018	0.982
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.018	0.982
I05-I09 Chronic rheumatic heart diseases	0.018	0.982
S90-S99 Injuries to the ankle and foot	0.018	0.982
O20-O29 Other maternal disorders predominantly related to pregnancy	0.018	0.982
I95-I99 Other and unspecified disorders of the circulatory system	0.018	0.982
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.018	0.982
N70-N77 Inflammatory diseases of female pelvic organs	0.017	0.982
O80-O84 Delivery	0.018	0.982
W00-W19 Falls	0.017	0.982
I00-I02 Acute rheumatic fever	0.017	0.982
Y60-Y69 Misadventures to patients during surgical and medical care	0.017	0.982
X60-X84 Intentional self-harm	0.017	0.982
K65-K67 Diseases of peritoneum	0.017	0.982
W50-W64 Exposure to animate mechanical forces	0.017	0.982
V20-V29 Motorcycle rider injured in transport accident	0.017	0.982
G40-G47 Episodic and paroxysmal disorders	0.017	0.982
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.017	0.982
X58-X59 Accidental exposure to other and unspecified factors	0.017	0.982
X40-X49 Accidental poisoning by and exposure to noxious substances	0.017	0.982
V80-V89 Other land transport accidents	0.017	0.982
V40-V49 Car occupant injured in transport accident	0.017	0.982
Y10-Y34 Event of undetermined intent	0.017	0.982
Y00-Y09 Assault	0.017	0.982
X50-X57 Overexertion, travel and privation	0.017	0.982
X20-X29 Contact with venomous animals and plants	0.017	0.982
X10-X19 Contact with heat and hot substances	0.017	0.982
X00-X09 Exposure to smoke, fire and flames	0.017	0.982
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.017	0.982
W75-W84 Other accidental threats to breathing	0.017	0.982
V98-V99 Other and unspecified transport accidents	0.017	0.982
V95-V97 Air and space transport accidents	0.017	0.982
V90-V94 Water transport accidents	0.017	0.982
V70-V79 Bus occupant injured in transport accident	0.017	0.982
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.017	0.982
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.017	0.982
V01-V09 Pedestrian injured in transport accident	0.017	0.982
Y35-Y36 Legal intervention and operations of war	0.017	0.982
X85-X99 Assault	0.017	0.982
X30-X39 Exposure to forces of nature	0.017	0.982
W65-W74 Accidental drowning and submersion	0.017	0.982
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.017	0.982
O94-O99 Other obstetric conditions, not elsewhere classified	0.017	0.982
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.017	0.982
D50-D53 Nutritional anaemias	0.017	0.982
W20-W49 Exposure to inanimate mechanical forces	0.017	0.983
B95-B98 Bacterial, viral and other infectious agents	0.017	0.983
O60-O75 Complications of labour and delivery	0.017	0.983
R06 Abnormalities of breathing	0.017	0.983
V10-V19 Pedal cyclist injured in transport accident	0.017	0.983
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.017	0.983
R05 Cough	0.017	0.983
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.017	0.983
G80-G83 Cerebral palsy and other paralytic syndromes	0.017	0.983
G35-G37 Demyelinating diseases of the central nervous system	0.017	0.983
G20-G26 Extrapyramidal and movement disorders	0.017	0.983
I20-I25 Ischaemic heart diseases	0.017	0.983
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.017	0.983
R69 Unknown and unspecified causes of morbidity	0.017	0.983
R55 Syncope and collapse	0.017	0.983
L80-L99 Other disorders of the skin and subcutaneous tissue	0.017	0.983
L00-L08 Infections of the skin and subcutaneous tissue	0.017	0.983
G30-G32 Other degenerative diseases of the nervous system	0.017	0.983
R12 Heartburn	0.017	0.983
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.017	0.983
K70-K77 Diseases of liver	0.017	0.983
O85-O92 Complications predominantly related to the puerperium	0.017	0.983
G90-G99 Other disorders of the nervous system	0.017	0.983
O00-O08 Pregnancy with abortive outcome	0.017	0.983
R15 Faecal incontinence	0.017	0.983
R14 Flatulence and related conditions	0.017	0.983
R51 Headache	0.017	0.983
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.017	0.983
R13 Dysphagia	0.017	0.983
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.017	0.983
R01 Cardiac murmurs and other cardiac sounds	0.017	0.983
R53 Malaise and fatigue	0.017	0.983
R02 Gangrene, not elsewhere classified	0.017	0.983
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.017	0.983
Z51 Other medical care	0.017	0.983
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.017	0.983
D80-D89 Certain disorders involving the immune mechanism	0.017	0.983
I70-I79 Diseases of arteries, arterioles and capillaries	0.017	0.983
G50-G59 Nerve, nerve root and plexus disorders	0.017	0.983
K50-K52 Noninfective enteritis and colitis	0.017	0.983
R59 Enlarged lymph nodes	0.017	0.983
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.017	0.983
D55-D59 Haemolytic anaemias	0.017	0.983
R04 Haemorrhage from respiratory passages	0.017	0.983
P90-P96 Other disorders originating in the perinatal period	0.017	0.983
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.017	0.983
P75-P78 Digestive system disorders of fetus and newborn	0.017	0.983
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.017	0.983
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.017	0.983
P35-P39 Infections specific to the perinatal period	0.017	0.983
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.017	0.983
P10-P15 Birth trauma	0.017	0.983
P05-P08 Disorders related to length of gestation and fetal growth	0.017	0.983
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.017	0.983
R63 Symptoms and signs concerning food and fluid intake	0.017	0.983
R56 Convulsions, not elsewhere classified	0.017	0.983
R00 Abnormalities of heart beat	0.017	0.983
R60 Oedema, not elsewhere classified	0.017	0.983
G00-G09 Inflammatory diseases of the central nervous system	0.017	0.983
R52 Pain, not elsewhere classified	0.017	0.983
G70-G73 Diseases of myoneural junction and muscle	0.017	0.983
Q60-Q64 Congenital malformations of the urinary system	0.017	0.983
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.017	0.983
Q50-Q56 Congenital malformations of genital organs	0.017	0.983
Z86.5 Personal history of other mental and behavioural disorders	0.017	0.983
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.017	0.983
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.017	0.983
Q80-Q89 Other congenital malformations	0.017	0.983
Q38-Q45 Other congenital malformations of the digestive system	0.017	0.983
Q00-Q07 Congenital malformations of the nervous system	0.017	0.983
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.017	0.983
Q35-Q37 Cleft lip and cleft palate	0.017	0.983
Q30-Q34 Congenital malformations of the respiratory system	0.017	0.983
Z86.0 Personal history of other neoplasms	0.017	0.983
R54 Senility	0.017	0.983
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.016	0.983
R03 Abnormal blood-pressure reading, without diagnosis	0.016	0.983
R68 Other general symptoms and signs	0.016	0.983
R57 Shock, not elsewhere classified	0.016	0.983
B15-B19 Viral hepatitis	0.016	0.983
A30-A49 Other bacterial diseases	0.016	0.983
L50-L54 Urticaria and erythema	0.016	0.983
S60-S69 Injuries to the wrist and hand	0.016	0.983
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.016	0.983
R58 Haemorrhage, not elsewhere classified	0.016	0.983
B90-B94 Sequelae of infectious and parasitic diseases	0.016	0.983
B20-B24 Human immunodeficiency virus [HIV] disease	0.016	0.983
A80-A89 Viral infections of the central nervous system	0.016	0.983
A50-A64 Infections with a predominantly sexual mode of transmission	0.016	0.983
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.016	0.983
R62 Lack of expected normal physiological development	0.016	0.983
R64 Cachexia	0.016	0.983
B99-B99 Other infectious diseases	0.016	0.983
B85-B89 Pediculosis, acariasis and other infestations	0.016	0.983
B65-B83 Helminthiases	0.016	0.983
B50-B64 Protozoal diseases	0.016	0.983
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.016	0.983
A75-A79 Rickettsioses	0.016	0.983
A70-A74 Other diseases caused by chlamydiae	0.016	0.983
A65-A69 Other spirochaetal diseases	0.016	0.983
A20-A28 Certain zoonotic bacterial diseases	0.016	0.983
A15-A19 Tuberculosis	0.016	0.983
L10-L14 Bullous disorders	0.016	0.983
L20-L30 Dermatitis and eczema	0.016	0.983
Q20-Q28 Congenital malformations of the circulatory system	0.016	0.983
R31 Unspecified haematuria	0.016	0.983
L40-L45 Papulosquamous disorders	0.016	0.983
K57 Diverticular disease of intestine	0.016	0.983
E70-E90 Metabolic disorders	0.016	0.983
D17 Benign lipomatous neoplasm	0.016	0.984
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.016	0.984
D60-D64 Aplastic and other anaemias	0.016	0.984
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.016	0.984
R18 Ascites	0.016	0.984
F30-F39 Mood [affective] disorders	0.016	0.984
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.016	0.984
D22 Melanocytic naevi	0.016	0.984
R10 Abdominal and pelvic pain	0.016	0.984
R17 Unspecified jaundice	0.016	0.984
F60-F69 Disorders of adult personality and behaviour	0.016	0.984
F99-F99 Unspecified mental disorder	0.016	0.984
F80-F89 Disorders of psychological development	0.016	0.984
A00-A09 Intestinal infectious diseases	0.016	0.984
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.016	0.984
F70-F79 Mental retardation	0.016	0.984
R61 Hyperhidrosis	0.016	0.984
Z86.1 Personal history of infectious and parasitic diseases	0.016	0.984
Z90.4 Acquired absence of other parts of digestive tract	0.016	0.984
F40-F48 Neurotic, stress-related and somatoform disorders	0.016	0.984
Z90.7 Acquired absence of genital organ(s)	0.016	0.984
D23 Other benign neoplasms of skin	0.016	0.984
E10-E14 Diabetes mellitus	0.016	0.984
R20 Disturbances of skin sensation	0.016	0.984
R50 Fever of unknown origin	0.016	0.984
D70-D77 Other diseases of blood and blood-forming organs	0.016	0.984
Z86.6 Personal history of diseases of the nervous system and sense organs	0.016	0.984
B25-B34 Other viral diseases	0.016	0.984
E50-E64 Other nutritional deficiencies	0.016	0.984
Z46 Fitting and adjustment of other devices	0.016	0.984
R21 Rash and other nonspecific skin eruption	0.016	0.984
B35-B49 Mycoses	0.016	0.984
F00-F09 Organic, including symptomatic, mental disorders	0.016	0.984
K63 Other diseases of intestine	0.016	0.984
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.016	0.984
E40-E46 Malnutrition	0.016	0.984
H80-H83 Diseases of inner ear	0.016	0.984
H60-H62 Diseases of external ear	0.016	0.984
D24 Benign neoplasm of breast	0.016	0.984
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.016	0.984
D18 Haemangioma and lymphangioma, any site	0.016	0.984
R93 Abnormal findings on diagnostic imaging of other body structures	0.016	0.984
R91 Abnormal findings on diagnostic imaging of lung	0.016	0.984
Z60 Problems related to social environment	0.016	0.984
I30-I52 Other forms of heart disease	0.016	0.984
H90-H95 Other disorders of ear	0.016	0.984
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.016	0.984
R23 Other skin changes	0.016	0.984
Z42 Follow-up care involving plastic surgery	0.016	0.984
E65-E68 Obesity and other hyperalimentation	0.016	0.984
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.016	0.984
D36 Benign neoplasm of other and unspecified sites	0.016	0.984
Z13 Special screening examination for other diseases and disorders	0.016	0.984
Z90.1 Acquired absence of breast(s)	0.016	0.984
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.016	0.984
D32 Benign neoplasm of meninges	0.016	0.984
D21 Other benign neoplasms of connective and other soft tissue	0.016	0.984
D11 Benign neoplasm of major salivary glands	0.016	0.984
D10 Benign neoplasm of mouth and pharynx	0.016	0.984
D33 Benign neoplasm of brain and other parts of central nervous system	0.016	0.984
D26 Other benign neoplasms of uterus	0.016	0.984
D16 Benign neoplasm of bone and articular cartilage	0.016	0.984
D34 Benign neoplasm of thyroid gland	0.016	0.984
Z48 Other surgical follow-up care	0.016	0.984
D30 Benign neoplasm of urinary organs	0.016	0.984
D29 Benign neoplasm of male genital organs	0.016	0.984
D28 Benign neoplasm of other and unspecified female genital organs	0.016	0.984
D14 Benign neoplasm of middle ear and respiratory system	0.016	0.984
I10 Essential (primary) hypertension	0.016	0.984
D31 Benign neoplasm of eye and adnexa	0.016	0.984
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.016	0.984
D19 Benign neoplasm of mesothelial tissue	0.016	0.984
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.016	0.984
Z08 Follow-up examination after treatment for malignant neoplasm	0.016	0.984
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.016	0.984
N32 Other disorders of bladder	0.016	0.984
Z85.4 Personal history of malignant neoplasm of genital organs	0.016	0.984
K58 Irritable bowel syndrome	0.016	0.984
Z41 Procedures for purposes other than remedying health state	0.016	0.984
Z40 Prophylactic surgery	0.016	0.984
R42 Dizziness and giddiness	0.015	0.984
R90 Abnormal findings on diagnostic imaging of central nervous system	0.015	0.984
Z49 Care involving dialysis	0.015	0.984
Z90.5 Acquired absence of kidney	0.015	0.984
C79 Secondary malignant neoplasm of other sites	0.015	0.984
M20 Acquired deformities of fingers and toes	0.016	0.984
Z52 Donors of organs and tissues	0.015	0.984
R92 Abnormal findings on diagnostic imaging of breast	0.015	0.984
Z54 Convalescence	0.015	0.984
Z44 Fitting and adjustment of external prosthetic device	0.015	0.984
Z63 Other problems related to primary support group, including family circumstances	0.015	0.984
Z57 Occupational exposure to risk-factors	0.015	0.984
Z56 Problems related to employment and unemployment	0.015	0.984
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.015	0.984
R79 Other abnormal findings of blood chemistry	0.015	0.984
Z65 Problems related to other psychosocial circumstances	0.015	0.984
Z64 Problems related to certain psychosocial circumstances	0.015	0.984
Z62 Other problems related to upbringing	0.015	0.984
Z61 Problems related to negative life events in childhood	0.015	0.984
Z59 Problems related to housing and economic circumstances	0.015	0.984
Z58 Problems related to physical environment	0.015	0.984
Z55 Problems related to education and literacy	0.015	0.984
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.015	0.984
E20-E35 Disorders of other endocrine glands	0.015	0.984
R94 Abnormal results of function studies	0.015	0.984
Z90.2 Acquired absence of lung [part of]	0.015	0.984
R47 Speech disturbances, not elsewhere classified	0.015	0.984
K40-K46 Hernia	0.015	0.984
Z90.8 Acquired absence of other organs	0.015	0.984
Z90.6 Acquired absence of other parts of urinary tract	0.015	0.984
Z90.3 Acquired absence of part of stomach	0.015	0.984
K56 Paralytic ileus and intestinal obstruction without hernia	0.015	0.984
R87 Abnormal findings in specimens from female genital organs	0.015	0.984
Z85.5 Personal history of malignant neoplasm of urinary tract	0.015	0.984
Z90.0 Acquired absence of part of head and neck	0.015	0.984
Z47 Other orthopaedic follow-up care	0.015	0.984
Z45 Adjustment and management of implanted device	0.015	0.984
K60 Fissure and fistula of anal and rectal regions	0.015	0.984
R73 Elevated blood glucose level	0.015	0.984
R26 Abnormalities of gait and mobility	0.015	0.984
R49 Voice disturbances	0.015	0.984
R72 Abnormality of white blood cells, not elsewhere classified	0.015	0.984
R76 Other abnormal immunological findings in serum	0.015	0.984
R74 Abnormal serum enzyme levels	0.015	0.984
R78 Findings of drugs and other substances, not normally found in blood	0.015	0.984
R77 Other abnormalities of plasma proteins	0.015	0.984
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.015	0.984
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.015	0.984
R71 Abnormality of red blood cells	0.015	0.984
J44 Other chronic obstructive pulmonary disease	0.015	0.984
N39 Other disorders of urinary system	0.015	0.984
R32 Unspecified urinary incontinence	0.015	0.984
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.015	0.984
M54 Dorsalgia	0.015	0.984
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.015	0.984
Z85.3 Personal history of malignant neoplasm of breast	0.015	0.985
Z92.2 Personal history of long-term (current) use of other medicaments	0.015	0.985
Z92.1 Personal history of long-term (current) use of anticoagulants	0.015	0.985
Z02 Examination and encounter for administrative purposes	0.015	0.985
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.015	0.985
R89 Abnormal findings in specimens from other organs, systems and tissues	0.015	0.985
R86 Abnormal findings in specimens from male genital organs	0.015	0.985
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.015	0.985
R84 Abnormal findings in specimens from respiratory organs and thorax	0.015	0.985
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.015	0.985
D35 Benign neoplasm of other and unspecified endocrine glands	0.015	0.985
R83 Abnormal findings in cerebrospinal fluid	0.015	0.985
R27 Other lack of coordination	0.015	0.985
Z04 Examination and observation for other reasons	0.015	0.985
K62 Other diseases of anus and rectum	0.015	0.985
Z75 Problems related to medical facilities and other health care	0.015	0.985
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.015	0.985
R82 Other abnormal findings in urine	0.015	0.985
R80 Isolated proteinuria	0.015	0.985
Z74 Problems related to care-provider dependency	0.015	0.985
Z73 Problems related to life-management difficulty	0.015	0.985
Z96.1 Presence of intraocular lens	0.015	0.985
D27 Benign neoplasm of ovary	0.015	0.985
R81 Glycosuria	0.015	0.985
C80 Malignant neoplasm without specification of site	0.015	0.985
Z50 Care involving use of rehabilitation procedures	0.015	0.985
Z76 Persons encountering health services in other circumstances	0.015	0.985
K61 Abscess of anal and rectal regions	0.015	0.985
Z11 Special screening examination for infectious and parasitic diseases	0.015	0.985
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.015	0.985
Z70 Counselling related to sexual attitude, behaviour and orientation	0.015	0.985
C76 Malignant neoplasm of other and ill-defined sites	0.015	0.985
H25 Senile cataract	0.015	0.985
R30 Pain associated with micturition	0.015	0.985
Z37 Outcome of delivery	0.015	0.985
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.015	0.985
K55 Vascular disorders of intestine	0.015	0.985
R96 Other sudden death, cause unknown	0.015	0.985
R95 Sudden infant death syndrome	0.015	0.985
R99 Other ill-defined and unspecified causes of mortality	0.015	0.985
R98 Unattended death	0.015	0.985
Z85.6 Personal history of leukaemia	0.015	0.985
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.015	0.985
Z10 Routine general health check-up of defined subpopulation	0.015	0.985
Z22 Carrier of infectious disease	0.015	0.985
Z85.0 Personal history of malignant neoplasm of digestive organs	0.015	0.985
Z80.0 Family history of malignant neoplasm of digestive organs	0.015	0.985
Z88.6 Personal history of allergy to analgesic agent	0.015	0.985
N35 Urethral stricture	0.015	0.985

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations