TreeWAS – Variant ID: rs4598084

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.212	0.788
T39.0 Salicylates	0.000	0.218	0.782
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.218	0.782
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.245	0.755
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.284	0.716
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.287	0.713
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.293	0.707
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.300	0.700
T43.6 Psychostimulants with abuse potential	0.000	0.309	0.691
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.321	0.679
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.331	0.669
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.336	0.664
T36 Poisoning by systemic antibiotics	0.000	0.341	0.659
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.353	0.647
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.367	0.633
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.382	0.618
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.390	0.610
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.392	0.608
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.418	0.582
T48.5 Anti-common-cold drugs	0.000	0.420	0.580
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.430	0.570
T39.1 4-Aminophenol derivatives	0.000	0.431	0.569
T50.4 Drugs affecting uric acid metabolism	0.000	0.431	0.569
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.431	0.569
T39.4 Antirheumatics, not elsewhere classified	0.000	0.435	0.565
T39.2 Pyrazolone derivatives	0.000	0.435	0.565
T43.2 Other and unspecified antidepressants	0.000	0.442	0.558
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.443	0.557
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.451	0.549
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.458	0.542
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.460	0.540
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.462	0.538
T36.3 Macrolides	0.000	0.465	0.535
T40.4 Other synthetic narcotics	0.000	0.469	0.531
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.473	0.526
T50.1 Loop [high-ceiling] diuretics	0.000	0.489	0.511
T43.9 Psychotropic drug, unspecified	0.000	0.489	0.510
T36.4 Tetracyclines	0.000	0.490	0.510
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.490	0.510
T47.0 Histamine H(2)-receptor antagonists	0.000	0.492	0.507
T50.7 Analeptics and opioid receptor antagonists	0.000	0.493	0.507
T50.5 Appetite depressants	0.000	0.493	0.507
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.493	0.507
T50.0 Mineralocorticoids and their antagonists	0.000	0.493	0.507
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.493	0.506
T42.1 Iminostilbenes	0.000	0.494	0.506
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.495	0.505
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.498	0.502
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.498	0.502
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.498	0.502
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.498	0.502
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.498	0.502
T44.0 Anticholinesterase agents	0.000	0.498	0.502
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.499	0.501
T40.6 Other and unspecified narcotics	0.000	0.503	0.497
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.503	0.497
T40.5 Cocaine	0.000	0.504	0.496
T36.8 Other systemic antibiotics	0.000	0.506	0.494
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.509	0.490
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.520	0.480
T48.4 Expectorants	0.000	0.520	0.480
T48.3 Antitussives	0.000	0.520	0.480
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.520	0.480
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.520	0.480
T48.0 Oxytocic drugs	0.000	0.520	0.480
T40.1 Heroin	0.000	0.526	0.474
T36.9 Systemic antibiotic, unspecified	0.000	0.527	0.473
T36.7 Antifungal antibiotics, systemically used	0.000	0.527	0.473
T36.6 Rifamycins	0.000	0.527	0.473
T36.5 Aminoglycosides	0.000	0.527	0.473
T36.2 Chloramphenicol group	0.000	0.527	0.473
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.527	0.473
T36.0 Penicillins	0.000	0.527	0.473
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.530	0.470
T46.1 Calcium-channel blockers	0.000	0.531	0.468
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.536	0.464
T42.2 Succinimides and oxazolidinediones	0.000	0.536	0.464
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.545	0.455
T47.6 Antidiarrhoeal drugs	0.000	0.546	0.454
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.546	0.454
T40.8 Lysergide [LSD]	0.000	0.546	0.454
T40.7 Cannabis (derivatives)	0.000	0.546	0.454
T40.0 Opium	0.000	0.546	0.454
T50.8 Diagnostic agents	0.000	0.551	0.449
T42.3 Barbiturates	0.000	0.555	0.445
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.557	0.443
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.557	0.443
T47.7 Emetics	0.000	0.557	0.443
T47.5 Digestants	0.000	0.557	0.443
T47.3 Saline and osmotic laxatives	0.000	0.557	0.443
T40.3 Methadone	0.000	0.561	0.438
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.566	0.434
T47.2 Stimulant laxatives	0.000	0.567	0.433
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.567	0.433
T42.0 Hydantoin derivatives	0.000	0.569	0.431
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.571	0.429
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.581	0.419
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.582	0.418
T47.4 Other laxatives	0.000	0.584	0.415
T45.0 Antiallergic and antiemetic drugs	0.000	0.589	0.411
T49.9 Topical agent, unspecified	0.000	0.591	0.409
T49.8 Other topical agents	0.000	0.591	0.409
T49.7 Dental drugs, topically applied	0.000	0.591	0.409
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.591	0.409
T49.5 Ophthalmological drugs and preparations	0.000	0.591	0.409
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.591	0.409
T49.3 Emollients, demulcents and protectants	0.000	0.591	0.409
T49.2 Local astringents and local detergents	0.000	0.591	0.409
T49.1 Antipruritics	0.000	0.591	0.409
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.614	0.386
T46.7 Peripheral vasodilators	0.000	0.614	0.386
T45.2 Vitamins, not elsewhere classified	0.000	0.626	0.373
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.628	0.371
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.630	0.370
T41.5 Therapeutic gases	0.000	0.634	0.366
T41.4 Anaesthetic, unspecified	0.000	0.634	0.366
T41.3 Local anaesthetics	0.000	0.634	0.366
T41.1 Intravenous anaesthetics	0.000	0.634	0.366
T41.0 Inhaled anaesthetics	0.000	0.634	0.366
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.640	0.359
T45.8 Other primarily systemic and haematological agents	0.000	0.640	0.359
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.640	0.359
T45.6 Fibrinolysis-affecting drugs	0.000	0.640	0.359
T45.3 Enzymes, not elsewhere classified	0.000	0.640	0.359
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.643	0.356
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.650	0.349
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.652	0.348
T45.4 Iron and its compounds	0.000	0.659	0.340
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.663	0.337
T37.5 Antiviral drugs	0.000	0.663	0.337
T37.4 Anthelminthics	0.000	0.663	0.337
T37.3 Other antiprotozoal drugs	0.000	0.663	0.337
T37.1 Antimycobacterial drugs	0.000	0.663	0.337
T37.0 Sulphonamides	0.000	0.663	0.337
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.667	0.333
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.679	0.321
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.001	0.683	0.317
T42.4 Benzodiazepines	0.000	0.684	0.316
T41.2 Other and unspecified general anaesthetics	0.000	0.685	0.315
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.688	0.311
T40.2 Other opioids	0.000	0.704	0.296
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.718	0.282
T45.5 Anticoagulants	0.001	0.760	0.239
T38.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.767	0.232
T38.0 Glucocorticoids and synthetic analogues	0.001	0.771	0.229
T38.9 Other and unspecified hormone antagonists	0.001	0.772	0.227
T38.7 Androgens and anabolic congeners	0.001	0.772	0.227
T38.4 Oral contraceptives	0.001	0.772	0.227
T38.2 Antithyroid drugs	0.001	0.772	0.227
T38.1 Thyroid hormones and substitutes	0.001	0.782	0.217
T38.5 Other oestrogens and progestogens	0.001	0.784	0.215
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.001	0.826	0.173
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.860	0.139
O75 Other complications of labour and delivery, not elsewhere classified	0.108	0.892	0.000
O70.0 First degree perineal laceration during delivery	0.108	0.892	0.000
O70 Perineal laceration during delivery	0.107	0.893	0.000
O70.1 Second degree perineal laceration during delivery	0.103	0.897	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.101	0.899	0.000
O60-O75 Complications of labour and delivery	0.100	0.900	0.000
O72.0 Third-stage haemorrhage	0.097	0.903	0.000
O75.0 Maternal distress during labour and delivery	0.097	0.903	0.000
O72 Postpartum haemorrhage	0.095	0.905	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.095	0.905	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.092	0.908	0.000
O70.9 Perineal laceration during delivery, unspecified	0.089	0.911	0.000
O75.8 Other specified complications of labour and delivery	0.088	0.912	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.085	0.915	0.000
O75.3 Other infection during labour	0.081	0.919	0.000
O75.4 Other complications of obstetric surgery and procedures	0.078	0.922	0.000
O75.1 Shock during or following labour and delivery	0.078	0.922	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.078	0.922	0.000
O73 Retained placenta and membranes, without haemorrhage	0.077	0.923	0.000
O74 Complications of anaesthesia during labour and delivery	0.077	0.923	0.000
O61 Failed induction of labour	0.076	0.923	0.000
O70.3 Fourth degree perineal laceration during delivery	0.075	0.925	0.000
O60 Preterm delivery	0.072	0.928	0.000
O62 Abnormalities of forces of labour	0.072	0.928	0.000
O75.9 Complication of labour and delivery, unspecified	0.069	0.930	0.000
O72.3 Postpartum coagulation defects	0.068	0.932	0.000
Z37.0 Single live birth	0.065	0.935	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.064	0.936	0.000
G95.8 Other specified diseases of spinal cord	0.000	0.936	0.064
G95 Other diseases of spinal cord	0.000	0.938	0.062
O73.0 Retained placenta, without haemorrhage	0.062	0.938	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.060	0.939	0.000
G95.9 Disease of spinal cord, unspecified	0.000	0.940	0.060
O61.1 Failed instrumental induction of labour	0.060	0.940	0.000
G95.2 Cord compression, unspecified	0.000	0.940	0.060
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.059	0.940	0.000
O66 Other obstructed labour	0.059	0.941	0.000
O61.0 Failed medical induction of labour	0.058	0.941	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.058	0.942	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.057	0.942	0.000
O62.2 Other uterine inertia	0.056	0.944	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.056	0.944	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.056	0.944	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.056	0.944	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.056	0.944	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.056	0.944	0.000
O65.0 Obstructed labour due to deformed pelvis	0.056	0.944	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.056	0.944	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.055	0.944	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.055	0.944	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.055	0.944	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.055	0.944	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.055	0.944	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.055	0.944	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.055	0.944	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.055	0.944	0.000
O71 Other obstetric trauma	0.055	0.945	0.000
O61.8 Other failed induction of labour	0.055	0.945	0.000
O62.3 Precipitate labour	0.054	0.946	0.000
O62.9 Abnormality of forces of labour, unspecified	0.053	0.947	0.000
O60.3 Preterm delivery without spontaneous labour	0.051	0.948	0.000
O60.2 Preterm spontaneous labour with term delivery	0.051	0.948	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.051	0.948	0.000
O60.0 Preterm labour without delivery	0.051	0.948	0.000
O62.8 Other abnormalities of forces of labour	0.051	0.948	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.051	0.949	0.000
O61.9 Failed induction of labour, unspecified	0.051	0.949	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.051	0.949	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.050	0.950	0.000
O62.1 Secondary uterine inertia	0.050	0.950	0.000
G95.1 Vascular myelopathies	0.000	0.951	0.049
O62.0 Primary inadequate contractions	0.048	0.952	0.000
O70.2 Third degree perineal laceration during delivery	0.048	0.952	0.000
O67.8 Other intrapartum haemorrhage	0.048	0.952	0.000
O66.4 Failed trial of labour, unspecified	0.048	0.952	0.000
O72.1 Other immediate postpartum haemorrhage	0.047	0.953	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.046	0.954	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.046	0.954	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.045	0.955	0.000
O66.8 Other specified obstructed labour	0.044	0.956	0.000
O63 Long labour	0.043	0.957	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.042	0.957	0.000
O66.1 Obstructed labour due to locked twins	0.042	0.957	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.042	0.957	0.000
O66.9 Obstructed labour, unspecified	0.041	0.958	0.000
O71.8 Other specified obstetric trauma	0.041	0.959	0.000
O71.3 Obstetric laceration of cervix	0.041	0.959	0.000
O71.2 Postpartum inversion of uterus	0.040	0.960	0.000
O71.1 Rupture of uterus during labour	0.040	0.960	0.000
O71.0 Rupture of uterus before onset of labour	0.040	0.960	0.000
O71.9 Obstetric trauma, unspecified	0.039	0.961	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.038	0.962	0.000
O71.4 Obstetric high vaginal laceration alone	0.038	0.962	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.037	0.963	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.036	0.964	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.036	0.964	0.000
O71.5 Other obstetric injury to pelvic organs	0.035	0.964	0.000
O66.2 Obstructed labour due to unusually large foetus	0.035	0.965	0.000
G95.0 Syringomyelia and syringobulbia	0.000	0.966	0.034
O71.7 Obstetric haematoma of pelvis	0.033	0.966	0.000
O64.5 Obstructed labour due to compound presentation	0.033	0.966	0.000
O63.0 Prolonged first stage (of labour)	0.033	0.967	0.000
H53.0 Amblyopia ex anopsia	0.000	0.967	0.033
O64.4 Obstructed labour due to shoulder presentation	0.032	0.968	0.000
O64.2 Obstructed labour due to face presentation	0.032	0.968	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.032	0.968	0.000
O64.3 Obstructed labour due to brow presentation	0.032	0.968	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.031	0.969	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.030	0.970	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.030	0.970	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.029	0.971	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.029	0.971	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.027	0.973	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.026	0.974	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.026	0.974	0.000
O69.3 Labour and delivery complicated by short cord	0.026	0.974	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.025	0.975	0.000
Q05.9 Spina bifida, unspecified	0.000	0.976	0.024
O69.8 Labour and delivery complicated by other cord complications	0.024	0.976	0.000
O64.1 Obstructed labour due to breech presentation	0.023	0.976	0.000
O63.1 Prolonged second stage (of labour)	0.023	0.977	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.022	0.978	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.021	0.979	0.000
J33.9 Nasal polyp, unspecified	0.000	0.983	0.017
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.017	0.983	0.000
Q05 Spina bifida	0.000	0.986	0.014
O23.4 Unspecified infection of urinary tract in pregnancy	0.013	0.987	0.000
O23 Infections of genito-urinary tract in pregnancy	0.013	0.987	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.013	0.987	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.012	0.988	0.000
O63.9 Long labour, unspecified	0.012	0.988	0.000
O16 Unspecified maternal hypertension	0.011	0.989	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.011	0.989	0.000
O23.5 Infections of the genital tract in pregnancy	0.011	0.989	0.000
O28 Abnormal findings on antenatal screening of mother	0.011	0.989	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.000	0.989	0.010
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.010	0.990	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.000	0.990	0.010
Q05.6 Thoracic spina bifida without hydrocephalus	0.000	0.990	0.010
Q05.5 Cervical spina bifida without hydrocephalus	0.000	0.990	0.010
Q05.3 Sacral spina bifida with hydrocephalus	0.000	0.990	0.010
Q05.2 Lumbar spina bifida with hydrocephalus	0.000	0.990	0.010
Q05.1 Thoracic spina bifida with hydrocephalus	0.000	0.990	0.010
Q05.0 Cervical spina bifida with hydrocephalus	0.000	0.990	0.010
Z37 Outcome of delivery	0.010	0.990	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.000	0.990	0.010
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.010	0.990	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.009	0.990	0.000
O21 Excessive vomiting in pregnancy	0.009	0.991	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.009	0.991	0.000
O23.2 Infections of urethra in pregnancy	0.009	0.991	0.000
O23.1 Infections of bladder in pregnancy	0.009	0.991	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.009	0.991	0.000
O24 Diabetes mellitus in pregnancy	0.009	0.991	0.000
O29 Complications of anaesthesia during pregnancy	0.009	0.991	0.000
O25 Malnutrition in pregnancy	0.009	0.991	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
O23.0 Infections of kidney in pregnancy	0.009	0.991	0.000
O22 Venous complications in pregnancy	0.009	0.991	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.009	0.991	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.009	0.991	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.008	0.991	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.008	0.992	0.001
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O97 Death from sequelae of direct obstetric causes	0.008	0.992	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.008	0.992	0.000
O95 Obstetric death of unspecified cause	0.008	0.992	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.008	0.992	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.008	0.992	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.008	0.992	0.000
O15 Eclampsia	0.008	0.992	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.008	0.992	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.008	0.992	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.008	0.992	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.008	0.992	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.008	0.992	0.000
O21.0 Mild hyperemesis gravidarum	0.008	0.992	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.007	0.992	0.000
Z37.3 Twins, one liveborn and one stillborn	0.007	0.992	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
Z37.9 Outcome of delivery unspecified	0.007	0.993	0.000
Z37.7 Other multiple births, all stillborn	0.007	0.993	0.000
Z37.6 Other multiple births, some liveborn	0.007	0.993	0.000
Z37.4 Twins, both stillborn	0.007	0.993	0.000
N30.0 Acute cystitis	0.007	0.993	0.000
O21.9 Vomiting of pregnancy, unspecified	0.007	0.993	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.007	0.993	0.000
Z37.5 Other multiple births, all liveborn	0.007	0.993	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O20 Haemorrhage in early pregnancy	0.007	0.993	0.000
O21.8 Other vomiting complicating pregnancy	0.007	0.993	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.007	0.993	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O22.1 Genital varices in pregnancy	0.007	0.993	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.007	0.993	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.007	0.993	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.007	0.993	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.007	0.993	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.007	0.993	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.007	0.993	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.007	0.993	0.000
O29.6 Failed or difficult intubation during pregnancy	0.007	0.993	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.007	0.993	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.007	0.993	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.007	0.993	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.007	0.993	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.007	0.993	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.007	0.993	0.000
O22.9 Venous complication in pregnancy, unspecified	0.007	0.993	0.000
O22.8 Other venous complications in pregnancy	0.007	0.993	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.007	0.993	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.007	0.993	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.007	0.993	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.007	0.993	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.006	0.993	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.006	0.993	0.000
O26.5 Maternal hypotension syndrome	0.006	0.994	0.000
O15.2 Eclampsia in the puerperium	0.006	0.994	0.000
O26.9 Pregnancy-related condition, unspecified	0.006	0.994	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
M23.3 Other meniscus derangements	0.006	0.994	0.000
Z37.1 Single stillbirth	0.006	0.994	0.000
O14.9 Preeclampsia, unspecified	0.006	0.994	0.000
O22.4 Haemorrhoids in pregnancy	0.006	0.994	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O96.9 Death from unspecified obstetric cause	0.006	0.994	0.000
O96.1 Death from indirect obstetric cause	0.006	0.994	0.000
O96.0 Death from direct obstetric cause	0.006	0.994	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.006	0.994	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.006	0.994	0.000
O97.0 Death from sequelae of direct obstetric cause	0.006	0.994	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O26.4 Herpes gestationis	0.006	0.994	0.000
O26.1 Low weight gain in pregnancy	0.006	0.994	0.000
O14.0 Moderate preeclampsia	0.006	0.994	0.000
O15.9 Eclampsia, unspecified as to time period	0.006	0.994	0.000
O15.1 Eclampsia in labour	0.006	0.994	0.000
O15.0 Eclampsia in pregnancy	0.006	0.994	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.006	0.994	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O85-O92 Complications predominantly related to the puerperium	0.006	0.994	0.000
Q00-Q07 Congenital malformations of the nervous system	0.000	0.994	0.006
O14.2 HELLP syndrome	0.005	0.994	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.005	0.994	0.000
O26.0 Excessive weight gain in pregnancy	0.005	0.995	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.005	0.995	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.005	0.995	0.000
O26.2 Pregnancy care of habitual aborter	0.005	0.995	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O20.8 Other haemorrhage in early pregnancy	0.005	0.995	0.000
O21.2 Late vomiting of pregnancy	0.005	0.995	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.005	0.995	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.005	0.995	0.000
O90 Complications of the puerperium, not elsewhere classified	0.005	0.995	0.000
O80-O84 Delivery	0.005	0.995	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.005	0.995	0.000
M23.37 Other meniscus derangements-Capsular lig	0.005	0.995	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.005	0.995	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.004	0.995	0.000
N88 Other noninflammatory disorders of cervix uteri	0.005	0.995	0.000
Q03 Congenital hydrocephalus	0.000	0.995	0.004
I27.2 Other secondary pulmonary hypertension	0.000	0.995	0.005
S02.20 Fracture of nasal bones (closed)	0.000	0.996	0.004
O89 Complications of anaesthesia during the puerperium	0.004	0.996	0.000
O88 Obstetric embolism	0.004	0.996	0.000
O20.0 Threatened abortion	0.004	0.996	0.000
O90.2 Haematoma of obstetric wound	0.004	0.996	0.000
Q06 Other congenital malformations of spinal cord	0.000	0.996	0.004
Q01 Encephalocele	0.000	0.996	0.004
Q00 Anencephaly and similar malformations	0.000	0.996	0.004
Q02 Microcephaly	0.000	0.996	0.004
O90.9 Complication of the puerperium, unspecified	0.004	0.996	0.000
J33.1 Polypoid sinus degeneration	0.000	0.996	0.004
O90.0 Disruption of Caesarean section wound	0.004	0.996	0.000
Q04 Other congenital malformations of brain	0.000	0.996	0.004
G96 Other disorders of central nervous system	0.000	0.996	0.004
Q07 Other congenital malformations of nervous system	0.000	0.996	0.004
G90-G99 Other disorders of the nervous system	0.000	0.996	0.004
O92.1 Cracked nipple associated with childbirth	0.004	0.996	0.000
J33 Nasal polyp	0.000	0.996	0.004
O14.1 Severe preeclampsia	0.004	0.996	0.000
N88.1 Old laceration of cervix uteri	0.004	0.996	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.004	0.996	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.996	0.004
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.996	0.004
N88.3 Incompetence of cervix uteri	0.004	0.996	0.000
O90.5 Postpartum thyroiditis	0.004	0.996	0.000
O90.4 Postpartum acute renal failure	0.004	0.996	0.000
O90.3 Cardiomyopathy in the puerperium	0.004	0.996	0.000
O83 Other assisted single delivery	0.004	0.996	0.000
O26.8 Other specified pregnancy-related conditions	0.004	0.996	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.000	0.996	0.004
O84 Multiple delivery	0.004	0.996	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.004	0.996	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.004	0.996	0.000
O91 Infections of breast associated with childbirth	0.003	0.996	0.000
N88.2 Stricture and stenosis of cervix uteri	0.004	0.996	0.000
O92.7 Other and unspecified disorders of lactation	0.003	0.996	0.000
O92.6 Galactorrhoea	0.003	0.996	0.000
O92.5 Suppressed lactation	0.003	0.996	0.000
O92.4 Hypogalactia	0.003	0.996	0.000
O92.3 Agalactia	0.003	0.996	0.000
O92.0 Retracted nipple associated with childbirth	0.003	0.996	0.000
G90 Disorders of autonomic nervous system	0.000	0.996	0.004
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.000	0.996	0.004
O86 Other puerperal infections	0.003	0.996	0.000
G96.9 Disorder of central nervous system, unspecified	0.000	0.996	0.003
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.004	0.996	0.000
N88.0 Leukoplakia of cervix uteri	0.003	0.996	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.000	0.996	0.003
Q03.8 Other congenital hydrocephalus	0.000	0.996	0.003
Q03.1 Atresia of foramina of Magendie and Luschka	0.000	0.996	0.003
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.996	0.003
O90.1 Disruption of perineal obstetric wound	0.003	0.996	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.000	0.997	0.003
M79.2 Neuralgia and neuritis, unspecified	0.000	0.997	0.003
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.003	0.997	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.003	0.997	0.000
O89.6 Failed or difficult intubation during the puerperium	0.003	0.997	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.003	0.997	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.003	0.997	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.003	0.997	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.003	0.997	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.003	0.997	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.003	0.997	0.000
O88.8 Other obstetric embolism	0.003	0.997	0.000
O88.3 Obstetric pyaemic and septic embolism	0.003	0.997	0.000
O88.2 Obstetric blood-clot embolism	0.003	0.997	0.000
O88.1 Amniotic fluid embolism	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations