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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4603427
log Bayes Factor = 11.9779
Chromosome 13   position 40,725,689  (GRCh37) Explore rs4603427 on Ensembl!
Variant rs4603427 is part of Cluster X0263

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
F30-F39 Mood [affective] disorders
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter VIII Diseases of the ear and mastoid process
0.999 0.001 0.000
H65-H75 Diseases of middle ear and mastoid
0.999 0.001 0.000
F32 Depressive episode
0.998 0.002 0.000
F32.9 Depressive episode, unspecified
0.996 0.004 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.994 0.006 0.000
H72 Perforation of tympanic membrane
0.993 0.007 0.000
C64-C68 Malignant neoplasms of urinary tract
0.983 0.017 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.982 0.018 0.000
Chapter XX External causes of morbidity and mortality
0.981 0.019 0.000
H66 Suppurative and unspecified otitis media
0.977 0.023 0.000
M15-M19 Arthrosis
0.974 0.026 0.000
M70-M79 Other soft tissue disorders
0.972 0.028 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.971 0.029 0.000
M19 Other arthrosis
0.969 0.031 0.000
M05-M14 Inflammatory polyarthropathies
0.968 0.032 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.966 0.034 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.962 0.038 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.960 0.040 0.000
M19.9 Arthrosis, unspecified
0.959 0.041 0.000
M45-M49 Spondylopathies
0.957 0.043 0.000
C78.7 Secondary malignant neoplasm of liver
0.945 0.055 0.000
C67 Malignant neoplasm of bladder
0.945 0.055 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.945 0.055 0.000
C34 Malignant neoplasm of bronchus and lung
0.939 0.061 0.000
H72.8 Other perforations of tympanic membrane
0.932 0.068 0.000
M48 Other spondylopathies
0.929 0.071 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.922 0.078 0.000
T42.4 Benzodiazepines
0.921 0.079 0.000
S20-S29 Injuries to the thorax
0.921 0.079 0.000
C79 Secondary malignant neoplasm of other sites
0.920 0.080 0.000
M75 Shoulder lesions
0.918 0.082 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.917 0.083 0.000
H66.9 Otitis media, unspecified
0.917 0.083 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.916 0.084 0.000
M48.0 Spinal stenosis
0.913 0.087 0.000
M13 Other arthritis
0.908 0.092 0.000
F31 Bipolar affective disorder
0.907 0.093 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.905 0.095 0.000
H66.3 Other chronic suppurative otitis media
0.904 0.096 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.897 0.103 0.000
M65-M68 Disorders of synovium and tendon
0.891 0.109 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.891 0.109 0.000
C67.2 Lateral wall of bladder
0.890 0.110 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.886 0.114 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.886 0.114 0.000
C43 Malignant melanoma of skin
0.881 0.119 0.000
C34.1 Upper lobe, bronchus or lung
0.878 0.122 0.000
M13.9 Arthritis, unspecified
0.877 0.123 0.000
M86-M90 Other osteopathies
0.876 0.124 0.000
H65 Nonsuppurative otitis media
0.875 0.125 0.000
M19.98 Arthrosis, unspecified (Other)
0.874 0.126 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.874 0.126 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.871 0.129 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.865 0.135 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.862 0.138 0.000
F60-F69 Disorders of adult personality and behaviour
0.862 0.138 0.000
M19.0 Primary arthrosis of other joints
0.857 0.143 0.000
Chapter VII Diseases of the eye and adnexa
0.852 0.148 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.849 0.151 0.000
M48.09 Spinal stenosis (Site unspecified)
0.845 0.155 0.000
H53-H54 Visual disturbances and blindness
0.845 0.155 0.000
M75.4 Impingement syndrome of shoulder
0.844 0.156 0.000
T66-T78 Other and unspecified effects of external causes
0.844 0.156 0.000
H53 Visual disturbances
0.842 0.158 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.842 0.158 0.000
M06 Other rheumatoid arthritis
0.838 0.162 0.000
H53.8 Other visual disturbances
0.837 0.163 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.834 0.166 0.000
F32.0 Mild depressive episode
0.831 0.169 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.828 0.172 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.825 0.175 0.000
F05.9 Delirium, unspecified
0.824 0.176 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.820 0.180 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.818 0.182 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.818 0.182 0.000
C67.9 Bladder, unspecified
0.814 0.186 0.000
M72 Fibroblastic disorders
0.813 0.187 0.000
W50-W64 Exposure to animate mechanical forces
0.811 0.189 0.000
Chapter XXII Codes for special purposes
0.810 0.190 0.000
X60-X84 Intentional self-harm
0.809 0.191 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.807 0.193 0.000
H53.2 Diplopia
0.807 0.193 0.000
M46 Other inflammatory spondylopathies
0.805 0.195 0.000
T40.2 Other opioids
0.805 0.195 0.000
F03 Unspecified dementia
0.803 0.197 0.000
S10-S19 Injuries to the neck
0.802 0.198 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.800 0.199 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.800 0.200 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.799 0.201 0.000
Y00-Y09 Assault
0.796 0.203 0.000
T43.2 Other and unspecified antidepressants
0.796 0.203 0.000
C34.3 Lower lobe, bronchus or lung
0.795 0.205 0.000
C43.4 Malignant melanoma of scalp and neck
0.795 0.205 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.794 0.206 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.792 0.208 0.000
C77.8 Lymph nodes of multiple regions
0.790 0.210 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.788 0.212 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.788 0.212 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.786 0.214 0.000
H71 Cholesteatoma of middle ear
0.786 0.214 0.000
C34.9 Bronchus or lung, unspecified
0.786 0.214 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.785 0.215 0.000
F80-F89 Disorders of psychological development
0.785 0.215 0.000
M89 Other disorders of bone
0.782 0.218 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.782 0.218 0.000
C78.2 Secondary malignant neoplasm of pleura
0.782 0.218 0.000
V80-V89 Other land transport accidents
0.781 0.219 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.780 0.220 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.780 0.220 0.000
M75.2 Bicipital tendinitis
0.779 0.221 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.775 0.225 0.000
M17 Gonarthrosis [arthrosis of knee]
0.774 0.226 0.000
S70-S79 Injuries to the hip and thigh
0.772 0.228 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.772 0.228 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.771 0.229 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.769 0.231 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.768 0.232 0.000
F02 Dementia in other diseases classified elsewhere
0.766 0.234 0.000
M67 Other disorders of synovium and tendon
0.766 0.234 0.000
T36 Poisoning by systemic antibiotics
0.766 0.234 0.000
F32.1 Moderate depressive episode
0.766 0.234 0.000
X50-X57 Overexertion, travel and privation
0.765 0.235 0.000
S40-S49 Injuries to the shoulder and upper arm
0.765 0.235 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.762 0.237 0.000
M13.93 Arthritis, unspecified (Forearm)
0.762 0.238 0.000
M10 Gout
0.760 0.240 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.758 0.242 0.000
M75.5 Bursitis of shoulder
0.757 0.243 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.756 0.244 0.000
Chapter VI Diseases of the nervous system
0.756 0.244 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.755 0.245 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.755 0.245 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.752 0.247 0.000
H70 Mastoiditis and related conditions
0.751 0.249 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.750 0.250 0.000
V10-V19 Pedal cyclist injured in transport accident
0.750 0.250 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.749 0.251 0.000
H69 Other disorders of Eustachian tube
0.749 0.251 0.000
M60-M63 Disorders of muscles
0.748 0.252 0.000
H90-H95 Other disorders of ear
0.748 0.252 0.000
C78.0 Secondary malignant neoplasm of lung
0.748 0.252 0.000
Y40 Systemic antibiotics
0.746 0.254 0.000
M05 Seropositive rheumatoid arthritis
0.745 0.255 0.000
V40-V49 Car occupant injured in transport accident
0.744 0.256 0.000
S27 Injury of other and unspecified intrathoracic organs
0.744 0.256 0.000
F20 Schizophrenia
0.743 0.257 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.742 0.258 0.000
F30 Manic episode
0.741 0.259 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.741 0.259 0.000
C43.9 Malignant melanoma of skin, unspecified
0.739 0.261 0.000
M71 Other bursopathies
0.738 0.262 0.000
G90-G99 Other disorders of the nervous system
0.737 0.263 0.000
F99-F99 Unspecified mental disorder
0.737 0.263 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.736 0.264 0.000
M17.0 Primary gonarthrosis, bilateral
0.736 0.264 0.000
T78 Adverse effects, not elsewhere classified
0.735 0.265 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.735 0.265 0.000
M65 Synovitis and tenosynovitis
0.734 0.266 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.733 0.267 0.000
H74 Other disorders of middle ear and mastoid
0.732 0.268 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.732 0.268 0.000
C34.0 Main bronchus
0.732 0.268 0.000
F29 Unspecified nonorganic psychosis
0.731 0.269 0.000
M77 Other enthesopathies
0.731 0.269 0.000
M75.1 Rotator cuff syndrome
0.730 0.270 0.000
M15 Polyarthrosis
0.730 0.270 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.730 0.270 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.730 0.270 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.730 0.270 0.000
C77.0 Lymph nodes of head, face and neck
0.729 0.271 0.000
M06.9 Rheumatoid arthritis, unspecified
0.727 0.273 0.000
H72.0 Central perforation of tympanic membrane
0.725 0.275 0.000
N60-N64 Disorders of breast
0.725 0.275 0.000
C51-C58 Malignant neoplasms of female genital organs
0.724 0.276 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.724 0.276 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.724 0.276 0.000
H43-H45 Disorders of vitreous body and globe
0.723 0.277 0.000
M80-M85 Disorders of bone density and structure
0.723 0.277 0.000
S32 Fracture of lumbar spine and pelvis
0.722 0.277 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.722 0.278 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.720 0.280 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.720 0.280 0.000
C67.3 Anterior wall of bladder
0.720 0.280 0.000
M91-M94 Chondropathies
0.718 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
C67.4 Posterior wall of bladder
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
Chapter XIV Diseases of the genitourinary system
0.717 0.283 0.000
F38 Other mood [affective] disorders
0.716 0.283 0.000
F34 Persistent mood [affective] disorders
0.716 0.283 0.000
F39 Unspecified mood [affective] disorder
0.716 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.283 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.716 0.283 0.000
H68 Eustachian salpingitis and obstruction
0.716 0.283 0.000
H67 Otitis media in diseases classified elsewhere
0.716 0.283 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.716 0.284 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.716 0.284 0.000
F60 Specific personality disorders
0.716 0.284 0.000
F32.8 Other depressive episodes
0.716 0.284 0.000
M11 Other crystal arthropathies
0.715 0.285 0.000
W20-W49 Exposure to inanimate mechanical forces
0.715 0.285 0.000
C77.1 Intrathoracic lymph nodes
0.713 0.287 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.713 0.287 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.713 0.287 0.000
H72.2 Other marginal perforations of tympanic membrane
0.712 0.288 0.000
H72.1 Attic perforation of tympanic membrane
0.712 0.288 0.000
N64 Other disorders of breast
0.712 0.288 0.000
F00 Dementia in Alzheimer's disease
0.711 0.289 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.711 0.289 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.710 0.290 0.000
M76 Enthesopathies of lower limb, excluding foot
0.710 0.290 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.708 0.291 0.000
C77.5 Intrapelvic lymph nodes
0.707 0.293 0.000
S22.3 Fracture of rib
0.707 0.293 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.705 0.295 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.705 0.295 0.000
C65 Malignant neoplasm of renal pelvis
0.705 0.295 0.000
S20 Superficial injury of thorax
0.704 0.295 0.000
F33 Recurrent depressive disorder
0.704 0.296 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.704 0.296 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.704 0.296 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.704 0.296 0.000
T42.3 Barbiturates
0.704 0.296 0.000
T42.2 Succinimides and oxazolidinediones
0.704 0.296 0.000
T42.1 Iminostilbenes
0.704 0.296 0.000
T42.0 Hydantoin derivatives
0.704 0.296 0.000
H73 Other disorders of tympanic membrane
0.704 0.296 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.297 0.000
Y10-Y34 Event of undetermined intent
0.703 0.297 0.000
X85-X99 Assault
0.703 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
X30-X39 Exposure to forces of nature
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.703 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.297 0.000
W75-W84 Other accidental threats to breathing
0.703 0.297 0.000
W65-W74 Accidental drowning and submersion
0.703 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.297 0.000
V95-V97 Air and space transport accidents
0.703 0.297 0.000
V90-V94 Water transport accidents
0.703 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
M40-M43 Deforming dorsopathies
0.702 0.298 0.000
F05.8 Other delirium
0.701 0.299 0.000
H66.4 Suppurative otitis media, unspecified
0.700 0.299 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.700 0.299 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.700 0.299 0.000
H66.0 Acute suppurative otitis media
0.700 0.299 0.000
C67.5 Bladder neck
0.700 0.300 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.699 0.301 0.000
W00-W19 Falls
0.699 0.301 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.698 0.302 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.697 0.303 0.000
F69 Unspecified disorder of adult personality and behaviour
0.696 0.304 0.000
T92 Sequelae of injuries of upper limb
0.695 0.305 0.000
M13.94 Arthritis, unspecified (Hand)
0.695 0.305 0.000
T40.4 Other synthetic narcotics
0.695 0.305 0.000
M89.9 Disorder of bone, unspecified
0.695 0.305 0.000
M19.8 Other specified arthrosis
0.695 0.305 0.000
M19.2 Other secondary arthrosis
0.695 0.305 0.000
M14 Arthropathies in other diseases classified elsewhere
0.694 0.306 0.000
M12 Other specific arthropathies
0.694 0.306 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.694 0.306 0.000
M08 Juvenile arthritis
0.694 0.306 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.693 0.307 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.693 0.307 0.000
C66 Malignant neoplasm of ureter
0.692 0.308 0.000
N60 Benign mammary dysplasia
0.692 0.308 0.000
G95 Other diseases of spinal cord
0.692 0.308 0.000
M67.8 Other specified disorders of synovium and tendon
0.691 0.309 0.000
T78.4 Allergy, unspecified
0.690 0.310 0.000
W55 Bitten or struck by other mammals
0.690 0.310 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.689 0.310 0.000
F09 Unspecified organic or symptomatic mental disorder
0.689 0.310 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.689 0.310 0.000
M00-M03 Infectious arthropathies
0.689 0.311 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.688 0.312 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.688 0.312 0.000
C31 Malignant neoplasm of accessory sinuses
0.688 0.312 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.688 0.312 0.000
C37 Malignant neoplasm of thymus
0.688 0.312 0.000
C33 Malignant neoplasm of trachea
0.688 0.312 0.000
F17.2 Dependence syndrome
0.688 0.312 0.000
Y48 Anaesthetics and therapeutic gases
0.687 0.313 0.000
M49 Spondylopathies in diseases classified elsewhere
0.686 0.314 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.682 0.318 0.000
S31 Open wound of abdomen, lower back and pelvis
0.682 0.318 0.000
Y57 Other and unspecified drugs and medicaments
0.681 0.319 0.000
S90-S99 Injuries to the ankle and foot
0.680 0.319 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.679 0.321 0.000
M75.3 Calcific tendinitis of shoulder
0.679 0.321 0.000
M19.1 Posttraumatic arthrosis of other joints
0.678 0.322 0.000
C67.8 Overlapping lesion of bladder
0.677 0.323 0.000
C67.7 Urachus
0.677 0.323 0.000
C67.0 Trigone of bladder
0.677 0.323 0.000
T79-T79 Certain early complications of trauma
0.677 0.323 0.000
T43.9 Psychotropic drug, unspecified
0.677 0.323 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.677 0.323 0.000
T43.6 Psychostimulants with abuse potential
0.677 0.323 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.677 0.323 0.000
T18 Foreign body in alimentary tract
0.677 0.323 0.000
X20-X29 Contact with venomous animals and plants
0.677 0.323 0.000
C80 Malignant neoplasm without specification of site
0.674 0.325 0.000
T51 Toxic effect of alcohol
0.674 0.326 0.000
C34.8 Overlapping lesion of bronchus and lung
0.673 0.327 0.000
C34.2 Middle lobe, bronchus or lung
0.673 0.327 0.000
N00-N08 Glomerular diseases
0.673 0.327 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.670 0.329 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.670 0.330 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.670 0.330 0.000
H65.3 Chronic mucoid otitis media
0.670 0.330 0.000
S22.2 Fracture of sternum
0.670 0.330 0.000
H65.4 Other chronic nonsuppurative otitis media
0.669 0.330 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.668 0.332 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.668 0.332 0.000
T93 Sequelae of injuries of lower limb
0.668 0.332 0.000
C77.9 Lymph node, unspecified
0.666 0.334 0.000
F22 Persistent delusional disorders
0.666 0.334 0.000
M48.9 Spondylopathy, unspecified
0.666 0.334 0.000
M48.8 Other specified spondylopathies
0.666 0.334 0.000
M48.4 Fatigue fracture of vertebra
0.666 0.334 0.000
M48.3 Traumatic spondylopathy
0.666 0.334 0.000
M48.2 Kissing spine
0.666 0.334 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.666 0.334 0.000
H93 Other disorders of ear, not elsewhere classified
0.666 0.334 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.666 0.334 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.665 0.334 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.665 0.335 0.000
Y04 Assault by bodily force
0.665 0.335 0.000
M90 Osteopathies in diseases classified elsewhere
0.664 0.336 0.000
C67.1 Dome of bladder
0.664 0.336 0.000
V20-V29 Motorcycle rider injured in transport accident
0.660 0.340 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.660 0.340 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.660 0.340 0.000
S26 Injury of heart
0.660 0.340 0.000
S25 Injury of blood vessels of thorax
0.660 0.340 0.000
S24 Injury of nerves and spinal cord at thorax level
0.660 0.340 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.660 0.340 0.000
S21 Open wound of thorax
0.660 0.340 0.000
C79.6 Secondary malignant neoplasm of ovary
0.660 0.340 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.660 0.340 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.660 0.340 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.660 0.340 0.000
M75.8 Other shoulder lesions
0.658 0.342 0.000
M75.9 Shoulder lesion, unspecified
0.658 0.342 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.655 0.345 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.654 0.346 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.654 0.346 0.000
M48.04 Spinal stenosis (Thoracic region)
0.654 0.346 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.654 0.346 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.654 0.346 0.000
M13.8 Other specified arthritis
0.651 0.349 0.000
M13.1 Monoarthritis, not elsewhere classified
0.651 0.349 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.651 0.349 0.000
F31.8 Other bipolar affective disorders
0.650 0.350 0.000
F31.7 Bipolar affective disorder, currently in remission
0.650 0.350 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.650 0.350 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.650 0.350 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.650 0.350 0.000
M19.94 Arthrosis, unspecified (Hand)
0.650 0.350 0.000
T56 Toxic effect of metals
0.650 0.350 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.649 0.351 0.000
Chapter I Certain infectious and parasitic diseases
0.648 0.352 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.644 0.356 0.000
M70.4 Prepatellar bursitis
0.643 0.357 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.643 0.357 0.000
T40.8 Lysergide [LSD]
0.643 0.357 0.000
T40.7 Cannabis (derivatives)
0.643 0.357 0.000
T40.6 Other and unspecified narcotics
0.643 0.357 0.000
T40.5 Cocaine
0.643 0.357 0.000
T40.3 Methadone
0.643 0.357 0.000
T40.1 Heroin
0.643 0.357 0.000
T40.0 Opium
0.643 0.357 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.642 0.358 0.000
S22.4 Multiple fractures of ribs
0.641 0.359 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.641 0.359 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.641 0.359 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.641 0.359 0.000
M86 Osteomyelitis
0.640 0.360 0.000
C43.5 Malignant melanoma of trunk
0.640 0.360 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.639 0.361 0.000
M66 Spontaneous rupture of synovium and tendon
0.639 0.361 0.000
F05.1 Delirium superimposed on dementia
0.639 0.361 0.000
F05.0 Delirium not superimposed on dementia, so described
0.639 0.361 0.000
T59 Toxic effect of other gases, fumes and vapours
0.637 0.362 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.637 0.363 0.000
S27.2 Traumatic heamopneumothorax
0.636 0.363 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.636 0.364 0.000
F28 Other nonorganic psychotic disorders
0.635 0.364 0.000
F24 Induced delusional disorder
0.635 0.364 0.000
F21 Schizotypal disorder
0.635 0.364 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.635 0.365 0.000
S37 Injury of urinary and pelvic organs
0.635 0.365 0.000
S36 Injury of intra-abdominal organs
0.635 0.365 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.635 0.365 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.635 0.365 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.635 0.365 0.000
S12 Fracture of neck
0.634 0.366 0.000
Chapter XXI Factors influencing health status and contact with health services
0.633 0.367 0.000
N60.1 Diffuse cystic mastopathy
0.633 0.367 0.000
F23 Acute and transient psychotic disorders
0.633 0.367 0.000
C73 Malignant neoplasm of thyroid gland
0.633 0.367 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.632 0.368 0.000
C43.8 Overlapping malignant melanoma of skin
0.632 0.368 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.632 0.368 0.000
C43.0 Malignant melanoma of lip
0.632 0.368 0.000
C48.1 Specified parts of peritoneum
0.631 0.369 0.000
F81 Specific developmental disorders of scholastic skills
0.630 0.370 0.000
N64.5 Other signs and symptoms in breast
0.629 0.371 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.629 0.371 0.000
H65.1 Other acute nonsuppurative otitis media
0.627 0.373 0.000
H65.0 Acute serous otitis media
0.627 0.373 0.000
F25 Schizoaffective disorders
0.627 0.373 0.000
Y88 Sequelae of surgical and medical care as external cause
0.627 0.373 0.000
M13.98 Arthritis, unspecified (Other)
0.627 0.373 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.626 0.373 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.626 0.373 0.000
T46.7 Peripheral vasodilators
0.626 0.373 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.626 0.373 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.626 0.373 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.626 0.373 0.000
T46.1 Calcium-channel blockers
0.626 0.373 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.626 0.373 0.000
F02.3 Dementia in Parkinson's disease
0.626 0.374 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.626 0.374 0.000
V80 Animal-rider or occupant of animal-drawn vehicle injured in transport accident
0.626 0.374 0.000
M06.0 Seronegative rheumatoid arthritis
0.624 0.376 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.624 0.376 0.000
Y40.9 Systemic antibiotic, unspecified
0.624 0.376 0.000
G91 Hydrocephalus
0.623 0.377 0.000
N62 Hypertrophy of breast
0.623 0.377 0.000
C69 Malignant neoplasm of eye and adnexa
0.622 0.378 0.000
M46.4 Discitis, unspecified
0.621 0.379 0.000
S22.5 Flail chest
0.621 0.379 0.000
N64.4 Mastodynia
0.620 0.380 0.000
M06.3 Rheumatoid nodule
0.619 0.380 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.619 0.381 0.000
F68 Other disorders of adult personality and behaviour
0.618 0.382 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.618 0.382 0.000
F65 Disorders of sexual preference
0.618 0.382 0.000
F64 Gender identity disorders
0.618 0.382 0.000
F63 Habit and impulse disorders
0.618 0.382 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.618 0.382 0.000
F61 Mixed and other personality disorders
0.618 0.382 0.000
S29 Other and unspecified injuries of thorax
0.618 0.382 0.000
S22.30 Fracture of rib (closed)
0.615 0.385 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.614 0.386 0.000
W17 Other fall from one level to another
0.614 0.386 0.000
M19.08 Primary arthrosis of other joints (Other)
0.614 0.386 0.000
M19.06 Primary arthrosis of other joints-Lower leg
0.614 0.386 0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)
0.614 0.386 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.614 0.386 0.000
M19.02 Primary arthrosis of other joints (Upper arm)
0.614 0.386 0.000
M19.00 Primary arthrosis of other joints (Multiple sites)
0.614 0.386 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.614 0.386 0.000
M88 Paget's disease of bone [osteitis deformans]
0.614 0.386 0.000
H55-H59 Other disorders of eye and adnexa
0.613 0.387 0.000
F20.9 Schizophrenia, unspecified
0.612 0.388 0.000
S10 Superficial injury of neck
0.612 0.388 0.000
S22.0 Fracture of thoracic vertebra
0.612 0.388 0.000
T63 Toxic effect of contact with venomous animals
0.611 0.388 0.000
M10.9 Gout, unspecified
0.611 0.389 0.000
X51 Travel and motion
0.611 0.389 0.000
H53.1 Subjective visual disturbances
0.611 0.389 0.000
M89.8 Other specified disorders of bone
0.611 0.389 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.610 0.390 0.000
Z42 Follow-up care involving plastic surgery
0.610 0.390 0.000
T45.5 Anticoagulants
0.610 0.390 0.000
F06.7 Mild cognitive disorder
0.609 0.391 0.000
T45.0 Antiallergic and antiemetic drugs
0.609 0.391 0.000
Y59 Other and unspecified vaccines and biological substances
0.609 0.391 0.000
Y58 Bacterial vaccines
0.609 0.391 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.609 0.391 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.609 0.391 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.609 0.391 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.609 0.391 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.609 0.391 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.609 0.391 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.608 0.391 0.000
T91 Sequelae of injuries of neck and trunk
0.608 0.392 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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