TreeWAS – Variant ID: rs4613509

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C34.1 Upper lobe, bronchus or lung	0.046	0.954	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.027	0.973	0.000
M81.9 Osteoporosis, unspecified	0.019	0.981	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.017	0.983	0.000
M81.98 Osteoporosis, unspecified (Other)	0.016	0.984	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.015	0.985	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.014	0.986	0.000
M81 Osteoporosis without pathological fracture	0.014	0.986	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.014	0.986	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.014	0.986	0.000
M81.4 Drug-induced osteoporosis	0.013	0.987	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.013	0.987	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.011	0.988	0.000
M81.0 Postmenopausal osteoporosis	0.011	0.989	0.000
M81.1 Postoophorectomy osteoporosis	0.011	0.989	0.000
M81.8 Other osteoporosis	0.010	0.990	0.000
M81.6 Localised osteoporosis [Lequesne]	0.010	0.990	0.000
M81.5 Idiopathic osteoporosis	0.010	0.990	0.000
C34 Malignant neoplasm of bronchus and lung	0.010	0.990	0.000
M81.48 Drug-induced osteoporosis (Other)	0.010	0.990	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.010	0.990	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.010	0.990	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.010	0.990	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.010	0.990	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.010	0.990	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.010	0.990	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.010	0.990	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.010	0.990	0.000
M81.2 Osteoporosis of disuse	0.009	0.991	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.009	0.991	0.000
C32 Malignant neoplasm of larynx	0.009	0.991	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.009	0.991	0.000
N89.9 Noninflammatory disorder of vagina, unspecified	0.000	0.991	0.009
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.009	0.991	0.000
C32.0 Glottis	0.009	0.991	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.008	0.992	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.008	0.992	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.008	0.992	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.008	0.992	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.008	0.992	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.008	0.992	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.008	0.992	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.008	0.992	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.008	0.992	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.008	0.992	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.008	0.992	0.000
C32.9 Larynx, unspecified	0.008	0.992	0.000
C32.1 Supraglottis	0.008	0.992	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.008	0.992	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.008	0.992	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.008	0.992	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.008	0.992	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.008	0.992	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.008	0.992	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.008	0.992	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.008	0.992	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.008	0.992	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.007	0.992	0.000
M81.58 Idiopathic osteoporosis (Other)	0.007	0.992	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.007	0.992	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.007	0.992	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.007	0.992	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.007	0.992	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.007	0.992	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.007	0.992	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.007	0.992	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.007	0.992	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.007	0.992	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.007	0.992	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.007	0.992	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.007	0.992	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.007	0.992	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.007	0.992	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.007	0.992	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.007	0.992	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.007	0.992	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.007	0.992	0.000
M81.89 Other osteoporosis (Site unspecified)	0.007	0.992	0.000
M81.88 Other osteoporosis (Other)	0.007	0.992	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.007	0.992	0.000
M81.86 Other osteoporosis (Lower leg)	0.007	0.992	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.007	0.992	0.000
M81.84 Other osteoporosis (Hand)	0.007	0.992	0.000
M81.83 Other osteoporosis (Forearm)	0.007	0.992	0.000
M81.82 Other osteoporosis (Upper arm)	0.007	0.992	0.000
M81.81 Other osteoporosis (Shoulder region)	0.007	0.992	0.000
M81.80 Other osteoporosis (Multiple sites)	0.007	0.992	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.007	0.992	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.007	0.993	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.007	0.993	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.007	0.993	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.007	0.993	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.007	0.993	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.007	0.993	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.007	0.993	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.007	0.993	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.007	0.993	0.000
C34.8 Overlapping lesion of bronchus and lung	0.007	0.993	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.007	0.993	0.000
M81.28 Osteoporosis of disuse (Other)	0.007	0.993	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.007	0.993	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.007	0.993	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.007	0.993	0.000
M81.24 Osteoporosis of disuse (Hand)	0.007	0.993	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.007	0.993	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.007	0.993	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.007	0.993	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.007	0.993	0.000
C32.8 Overlapping lesion of larynx	0.007	0.993	0.000
C32.3 Laryngeal cartilage	0.007	0.993	0.000
C32.2 Subglottis	0.007	0.993	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.007	0.993	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.007	0.993	0.000
I37.1 Pulmonary valve insufficiency	0.000	0.993	0.007
C31 Malignant neoplasm of accessory sinuses	0.006	0.993	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.006	0.994	0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.000	0.994	0.006
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.994	0.006
M81.20 Osteoporosis of disuse (Multiple sites)	0.006	0.994	0.000
C38.4 Pleura	0.006	0.994	0.000
C34.2 Middle lobe, bronchus or lung	0.006	0.994	0.000
N94.1 Dyspareunia	0.000	0.994	0.006
C33 Malignant neoplasm of trachea	0.005	0.994	0.000
C30.0 Nasal cavity	0.005	0.994	0.000
C37 Malignant neoplasm of thymus	0.005	0.995	0.000
H33.2 Serous retinal detachment	0.005	0.995	0.000
C38.3 Mediastinum, part unspecified	0.005	0.995	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.005	0.995	0.000
C38.2 Posterior mediastinum	0.005	0.995	0.000
C38.1 Anterior mediastinum	0.005	0.995	0.000
C38.0 Heart	0.005	0.995	0.000
C34.9 Bronchus or lung, unspecified	0.005	0.995	0.000
C31.0 Maxillary sinus	0.005	0.995	0.000
C30.1 Middle ear	0.005	0.995	0.000
K14.0 Glossitis	0.000	0.995	0.005
C31.9 Accessory sinus, unspecified	0.005	0.995	0.000
C31.8 Overlapping lesion of accessory sinuses	0.005	0.995	0.000
C31.3 Sphenoidal sinus	0.005	0.995	0.000
C31.2 Frontal sinus	0.005	0.995	0.000
C31.1 Ethmoidal sinus	0.005	0.995	0.000
C39.9 Ill-defined sites within the respiratory system	0.005	0.995	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.005	0.995	0.000
C39.0 Upper respiratory tract, part unspecified	0.005	0.995	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.000	0.995	0.005
C09.9 Tonsil, unspecified	0.000	0.995	0.005
D22.7 Melanocytic naevi of lower limb, including hip	0.005	0.995	0.000
C02.9 Tongue, unspecified	0.004	0.996	0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.000	0.996	0.004
U80.1 Methicillin resistant agent	0.004	0.996	0.000
K14.9 Disease of tongue, unspecified	0.000	0.996	0.004
C34.0 Main bronchus	0.004	0.996	0.000
N94.5 Secondary dysmenorrhoea	0.000	0.996	0.004
C34.3 Lower lobe, bronchus or lung	0.004	0.996	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.004	0.996	0.000
L50.9 Urticaria, unspecified	0.000	0.996	0.004
Z29.1 Prophylactic immunotherapy	0.004	0.996	0.000
L28.0 Lichen simplex chronicus	0.004	0.996	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.004	0.996	0.000
M80-M85 Disorders of bone density and structure	0.004	0.996	0.000
U80 Agent resistant to penicillin and related antibiotics	0.004	0.996	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.004	0.996	0.000
M79.62 Pain in limb (Upper arm)	0.004	0.996	0.000
U80.0 Penicillin resistant agent	0.004	0.996	0.000
N94.2 Vaginismus	0.000	0.996	0.003
N94.0 Mittelschmerz	0.000	0.997	0.003
M22.2 Patellofemoral disorders	0.003	0.997	0.000
L03.2 Cellulitis of face	0.003	0.997	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.003	0.997	0.000
R23.8 Other and unspecified skin changes	0.003	0.997	0.000
C02.1 Border of tongue	0.003	0.997	0.000
Z94.8 Other transplanted organ and tissue status	0.003	0.997	0.000
M84 Disorders of continuity of bone	0.003	0.997	0.000
M83 Adult osteomalacia	0.003	0.997	0.000
C02.4 Lingual tonsil	0.003	0.997	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.003	0.997	0.000
M84.0 Malunion of fracture	0.003	0.997	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.003	0.997	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.003
U80.8 Agent resistant to other penicillin-related antibiotic	0.003	0.997	0.000
K14 Diseases of tongue	0.000	0.997	0.003
M84.02 Malunion of fracture (Upper arm)	0.003	0.997	0.000
N94.4 Primary dysmenorrhoea	0.000	0.997	0.003
M82 Osteoporosis in diseases classified elsewhere	0.003	0.997	0.000
M80 Osteoporosis with pathological fracture	0.002	0.997	0.000
M84.03 Malunion of fracture (Forearm)	0.003	0.997	0.000
H54.0 Blindness, both eyes	0.003	0.997	0.000
M84.4 Pathological fracture, not elsewhere classified	0.003	0.997	0.000
Z73.6 Limitation of activities due to disability	0.003	0.997	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.997	0.003
M83.1 Senile osteomalacia	0.003	0.997	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
M80.0 Postmenopausal osteoporosis with pathological fracture	0.002	0.997	0.000
M84.01 Malunion of fracture (Shoulder region)	0.003	0.997	0.000
H53.0 Amblyopia ex anopsia	0.003	0.997	0.000
Z29.0 Isolation	0.003	0.997	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M84.8 Other disorders of continuity of bone	0.003	0.997	0.000
C02.8 Overlapping lesion of tongue	0.003	0.997	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.003	0.997	0.000
C02.2 Ventral surface of tongue	0.003	0.997	0.000
C02.0 Dorsal surface of tongue	0.003	0.997	0.000
M84.08 Malunion of fracture (Other)	0.003	0.997	0.000
Z29 Need for other prophylactic measures	0.003	0.997	0.000
H54 Blindness and low vision	0.003	0.997	0.000
N94.6 Dysmenorrhoea, unspecified	0.000	0.997	0.003
M83.12 Senile osteomalacia (Upper arm)	0.002	0.997	0.000
M84.2 Delayed union of fracture	0.002	0.997	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.002	0.997	0.000
R23.2 Flushing	0.003	0.997	0.000
M83.9 Adult osteomalacia, unspecified	0.002	0.997	0.000
M83.5 Other drug-induced osteomalacia in adults	0.002	0.997	0.000
M83.4 Aluminum bone disease	0.002	0.997	0.000
M83.3 Adult osteomalacia due to malnutrition	0.002	0.997	0.000
M83.2 Adult osteomalacia due to malabsorption	0.002	0.997	0.000
M83.0 Puerperal osteomalacia	0.002	0.997	0.000
M84.9 Disorder of continuity of bone, unspecified	0.002	0.997	0.000
H54.6 Unqualified visual loss, one eye	0.002	0.998	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
M84.09 Malunion of fracture (Site unspecified)	0.002	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.998	0.000
K14.3 Hypertrophy of tongue papillae	0.000	0.998	0.002
M80.8 Other osteoporosis with pathological fracture	0.002	0.998	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.002	0.998	0.000
N94.3 Premenstrual tension syndrome	0.000	0.998	0.002
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
B97.5 Reovirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
K14.5 Plicated tongue	0.000	0.998	0.002
K14.4 Atrophy of tongue papillae	0.000	0.998	0.002
K14.2 Median rhomboid glossitis	0.000	0.998	0.002
M83.8 Other adult osteomalacia	0.002	0.998	0.000
I37 Pulmonary valve disorders	0.000	0.998	0.002
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.002	0.998	0.000
K14.1 Geographic tongue	0.000	0.998	0.002
R23.4 Changes in skin texture	0.002	0.998	0.000
R23 Other skin changes	0.002	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.002	0.998	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.002	0.998	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.002	0.998	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.002	0.998	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.002	0.998	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.002	0.998	0.000
R82.9 Other and unspecified abnormal finding in urine	0.000	0.998	0.002
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.002	0.998	0.000
H54.2 Low vision, both eyes	0.002	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.002	0.998	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.002	0.998	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.002	0.998	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.002	0.998	0.000
A63.0 Anogenital (venereal) warts	0.002	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.002	0.998	0.000
M22.0 Recurrent dislocation of patella	0.002	0.998	0.000
M84.3 Stress fracture, not elsewhere classified	0.002	0.998	0.000
M83.19 Senile osteomalacia (Site unspecified)	0.002	0.998	0.000
M83.18 Senile osteomalacia (Other)	0.002	0.998	0.000
M83.17 Senile osteomalacia (Ankle and foot)	0.002	0.998	0.000
M83.16 Senile osteomalacia (Lower leg)	0.002	0.998	0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.002	0.998	0.000
M83.14 Senile osteomalacia (Hand)	0.002	0.998	0.000
M83.13 Senile osteomalacia (Forearm)	0.002	0.998	0.000
M83.11 Senile osteomalacia (Shoulder region)	0.002	0.998	0.000
M83.10 Senile osteomalacia (Multiple sites)	0.002	0.998	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.002	0.998	0.000
C53.9 Cervix uteri, unspecified	0.000	0.998	0.002
M84.89 Other disorders of continuity of bone (Site unspecified)	0.002	0.998	0.000
M84.88 Other disorders of continuity of bone (Other)	0.002	0.998	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.002	0.998	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.002	0.998	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.002	0.998	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.002	0.998	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.002	0.998	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.002	0.998	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.002	0.998	0.000
S82.40 Fracture of fibula alone (closed)	0.002	0.998	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.998	0.002
M84.21 Delayed union of fracture (Shoulder region)	0.002	0.998	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.998	0.002
M80.88 Other osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.998	0.000
Z29.9 Prophylactic measure, unspecified	0.002	0.998	0.000
Z73 Problems related to life-management difficulty	0.002	0.998	0.000
Z29.2 Other prophylactic chemotherapy	0.002	0.998	0.000
H54.3 Unqualified visual loss, both eyes	0.002	0.998	0.000
H54.1 Blindness, one eye, low vision, other eye	0.002	0.998	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.002	0.998	0.000
M84.28 Delayed union of fracture (Other)	0.002	0.998	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.002	0.998	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.002	0.998	0.000
M84.24 Delayed union of fracture (Hand)	0.002	0.998	0.000
M84.23 Delayed union of fracture (Forearm)	0.002	0.998	0.000
M84.22 Delayed union of fracture (Upper arm)	0.002	0.998	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
M84.26 Delayed union of fracture (Lower leg)	0.002	0.998	0.000
M22.3 Other derangements of patella	0.002	0.998	0.000
K14.6 Glossodynia	0.000	0.998	0.002
M80.9 Unspecified osteoporosis with pathological fracture	0.001	0.998	0.001
M83.09 Puerperal osteomalacia (Site unspecified)	0.002	0.998	0.000
M83.08 Puerperal osteomalacia (Other)	0.002	0.998	0.000
M83.07 Puerperal osteomalacia (Ankle and foot)	0.002	0.998	0.000
M83.06 Puerperal osteomalacia (Lower leg)	0.002	0.998	0.000
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.002	0.998	0.000
M83.04 Puerperal osteomalacia (Hand)	0.002	0.998	0.000
M83.03 Puerperal osteomalacia (Forearm)	0.002	0.998	0.000
M83.02 Puerperal osteomalacia (Upper arm)	0.002	0.998	0.000
M83.01 Puerperal osteomalacia (Shoulder region)	0.002	0.998	0.000
M83.00 Puerperal osteomalacia (Multiple sites)	0.002	0.998	0.000
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.002	0.998	0.000
M83.28 Adult osteomalacia due to malabsorption (Other)	0.002	0.998	0.000
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.002	0.998	0.000
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.002	0.998	0.000
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.002	0.998	0.000
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.002	0.998	0.000
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.002	0.998	0.000
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.002	0.998	0.000
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.002	0.998	0.000
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.002	0.998	0.000
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.002	0.998	0.000
M83.38 Adult osteomalacia due to malnutrition (Other)	0.002	0.998	0.000
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.002	0.998	0.000
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.002	0.998	0.000
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.002	0.998	0.000
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.002	0.998	0.000
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.002	0.998	0.000
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.002	0.998	0.000
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.002	0.998	0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.002	0.998	0.000
M83.49 Aluminium bone disease (Site unspecified)	0.002	0.998	0.000
M83.48 Aluminium bone disease (Other)	0.002	0.998	0.000
M83.47 Aluminium bone disease (Ankle and foot)	0.002	0.998	0.000
M83.46 Aluminium bone disease (Lower leg)	0.002	0.998	0.000
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.002	0.998	0.000
M83.44 Aluminium bone disease (Hand)	0.002	0.998	0.000
M83.43 Aluminium bone disease (Forearm)	0.002	0.998	0.000
M83.42 Aluminium bone disease (Upper arm)	0.002	0.998	0.000
M83.41 Aluminium bone disease (Shoulder region)	0.002	0.998	0.000
M83.40 Aluminium bone disease (Multiple sites)	0.002	0.998	0.000
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.002	0.998	0.000
M83.58 Other drug-induced osteomalacia in adults (Other)	0.002	0.998	0.000
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.002	0.998	0.000
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.002	0.998	0.000
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.002	0.998	0.000
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.002	0.998	0.000
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.002	0.998	0.000
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.002	0.998	0.000
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.002	0.998	0.000
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.002	0.998	0.000
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.002	0.998	0.000
M83.98 Adult osteomalacia, unspecified (Other)	0.002	0.998	0.000
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.002	0.998	0.000
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.002	0.998	0.000
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M83.94 Adult osteomalacia, unspecified (Hand)	0.002	0.998	0.000
M83.93 Adult osteomalacia, unspecified (Forearm)	0.002	0.998	0.000
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.002	0.998	0.000
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.002	0.998	0.000
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.002	0.998	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.002	0.998	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.002	0.998	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.002	0.998	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.002	0.998	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.002	0.998	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.002	0.998	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.002	0.998	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.002	0.998	0.000
D73.0 Hyposplenism	0.002	0.998	0.000
H54.5 Low vision, one eye	0.002	0.998	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.002	0.998	0.000
H54.4 Blindness, one eye	0.002	0.998	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.002	0.998	0.000
M83.89 Other adult osteomalacia (Site unspecified)	0.002	0.998	0.000
M83.88 Other adult osteomalacia (Other)	0.002	0.998	0.000
M83.87 Other adult osteomalacia (Ankle and foot)	0.002	0.998	0.000
M83.86 Other adult osteomalacia (Lower leg)	0.002	0.998	0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.002	0.998	0.000
M83.84 Other adult osteomalacia (Hand)	0.002	0.998	0.000
M83.83 Other adult osteomalacia (Forearm)	0.002	0.998	0.000
M83.82 Other adult osteomalacia (Upper arm)	0.002	0.998	0.000
M83.81 Other adult osteomalacia (Shoulder region)	0.002	0.998	0.000
A63.8 Other specified predominantly sexually transmitted diseases	0.002	0.998	0.000
I37.9 Pulmonary valve disorder, unspecified	0.000	0.998	0.002
I37.8 Other pulmonary valve disorders	0.000	0.998	0.002
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.998	0.002
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.002	0.998	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.002	0.998	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.002	0.998	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.002	0.998	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.002	0.998	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.002	0.998	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.002	0.998	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.002	0.998	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.002	0.998	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.002	0.998	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.002	0.998	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.002	0.998	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.002	0.998	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.002	0.998	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.002	0.998	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.002	0.998	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.002	0.998	0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.002	0.998	0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.002	0.998	0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.002	0.998	0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.002	0.998	0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.002	0.998	0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.002	0.998	0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.002	0.998	0.000
A49.1 Streptococcal infection, unspecified	0.002	0.998	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.001	0.998	0.001
M84.06 Malunion of fracture (Lower leg)	0.002	0.998	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.998	0.002
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.002	0.998	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.002	0.998	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.002	0.998	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.002	0.998	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.002	0.998	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.002	0.998	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.002	0.998	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.002	0.998	0.000
K11.5 Sialolithiasis	0.002	0.998	0.000
S89.9 Unspecified injury of lower leg	0.000	0.998	0.002
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.002	0.998	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.002	0.998	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.002	0.998	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
Z73.8 Other problems related to life-management difficulty	0.002	0.998	0.000
N89 Other noninflammatory disorders of vagina	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations