TreeWAS – Variant ID: rs4615376

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I27.2 Other secondary pulmonary hypertension	0.598	0.402	0.000
I27 Other pulmonary heart diseases	0.592	0.408	0.000
I27.0 Primary pulmonary hypertension	0.580	0.420	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.571	0.429	0.000
I20.0 Unstable angina	0.555	0.445	0.000
I20 Angina pectoris	0.547	0.453	0.000
I20-I25 Ischaemic heart diseases	0.539	0.461	0.000
I25 Chronic ischaemic heart disease	0.536	0.464	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.536	0.464	0.000
I05-I09 Chronic rheumatic heart diseases	0.524	0.476	0.000
I08 Multiple valve diseases	0.519	0.481	0.000
Chapter IX Diseases of the circulatory system	0.517	0.483	0.000
I08.0 Disorders of both mitral and aortic valves	0.513	0.487	0.000
I05 Rheumatic mitral valve diseases	0.507	0.493	0.000
I05.2 Mitral stenosis with insufficiency	0.477	0.523	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.460	0.540	0.000
I20.9 Angina pectoris, unspecified	0.459	0.541	0.000
I25.3 Aneurysm of heart	0.445	0.555	0.000
I20.8 Other forms of angina pectoris	0.430	0.570	0.000
I27.1 Kyphoscoliotic heart disease	0.424	0.576	0.000
I05.9 Mitral valve disease, unspecified	0.424	0.576	0.000
I05.0 Mitral stenosis	0.415	0.585	0.000
I27.9 Pulmonary heart disease, unspecified	0.409	0.591	0.000
I25.1 Atherosclerotic heart disease	0.403	0.597	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.397	0.603	0.000
I06 Rheumatic aortic valve diseases	0.394	0.606	0.000
I27.8 Other specified pulmonary heart diseases	0.388	0.612	0.000
I25.6 Silent myocardial ischaemia	0.384	0.615	0.000
I08.8 Other multiple valve diseases	0.383	0.617	0.000
I09 Other rheumatic heart diseases	0.379	0.621	0.000
I28 Other diseases of pulmonary vessels	0.376	0.624	0.000
I00-I02 Acute rheumatic fever	0.375	0.625	0.000
I25.5 Ischaemic cardiomyopathy	0.374	0.626	0.000
I08.9 Multiple valve disease, unspecified	0.372	0.628	0.000
I23 Certain current complications following acute myocardial infarction	0.367	0.633	0.000
I05.8 Other mitral valve diseases	0.364	0.636	0.000
I05.1 Rheumatic mitral insufficiency	0.354	0.646	0.000
I22 Subsequent myocardial infarction	0.349	0.651	0.000
I20.1 Angina pectoris with documented spasm	0.314	0.686	0.000
I06.0 Rheumatic aortic stenosis	0.298	0.702	0.000
I06.1 Rheumatic aortic insufficiency	0.286	0.714	0.000
I07 Rheumatic tricuspid valve diseases	0.283	0.717	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.283	0.717	0.000
I06.8 Other rheumatic aortic valve diseases	0.283	0.717	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.283	0.717	0.000
I25.2 Old myocardial infarction	0.280	0.720	0.000
I09.9 Rheumatic heart disease, unspecified	0.275	0.725	0.000
I00 Rheumatic fever without mention of heart involvement	0.273	0.727	0.000
I09.8 Other specified rheumatic heart diseases	0.272	0.728	0.000
I09.2 Chronic rheumatic pericarditis	0.272	0.728	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.272	0.728	0.000
I09.0 Rheumatic myocarditis	0.272	0.728	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.269	0.730	0.000
I28.1 Aneurysm of pulmonary artery	0.269	0.730	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.269	0.730	0.000
I02 Rheumatic chorea	0.269	0.731	0.000
I01 Rheumatic fever with heart involvement	0.269	0.731	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.269	0.731	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.263	0.737	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.263	0.737	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.263	0.737	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.263	0.737	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.263	0.737	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.263	0.737	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.263	0.737	0.000
I28.8 Other specified diseases of pulmonary vessels	0.261	0.739	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.259	0.741	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.249	0.751	0.000
I23.8 Other current complications following acute myocardial infarction	0.244	0.756	0.000
I26 Pulmonary embolism	0.238	0.762	0.000
I24 Other acute ischaemic heart diseases	0.234	0.766	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.232	0.768	0.000
I22.8 Subsequent myocardial infarction of other sites	0.224	0.775	0.000
I07.9 Tricuspid valve disease, unspecified	0.203	0.797	0.000
I07.8 Other tricuspid valve diseases	0.203	0.797	0.000
I07.2 Tricuspid stenosis with insufficiency	0.203	0.797	0.000
I07.0 Tricuspid stenosis	0.203	0.797	0.000
I25.4 Coronary artery aneurysm	0.200	0.799	0.001
I95-I99 Other and unspecified disorders of the circulatory system	0.197	0.803	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.194	0.806	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.193	0.807	0.000
I01.8 Other acute rheumatic heart disease	0.193	0.807	0.000
I01.2 Acute rheumatic myocarditis	0.193	0.807	0.000
I01.1 Acute rheumatic endocarditis	0.193	0.807	0.000
I01.0 Acute rheumatic pericarditis	0.193	0.807	0.000
I02.9 Rheumatic chorea without heart involvement	0.193	0.807	0.000
I02.0 Rheumatic chorea with heart involvement	0.193	0.807	0.000
I24.1 Dressler's syndrome	0.175	0.825	0.000
I10-I15 Hypertensive diseases	0.171	0.829	0.000
I99 Other and unspecified disorders of circulatory system	0.171	0.829	0.000
I24.8 Other forms of acute ischaemic heart disease	0.160	0.840	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.152	0.848	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.144	0.856	0.000
I13 Hypertensive heart and renal disease	0.136	0.864	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.136	0.864	0.000
I12 Hypertensive renal disease	0.129	0.871	0.000
I12.0 Hypertensive renal disease with renal failure	0.115	0.885	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.114	0.886	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.111	0.889	0.000
I07.1 Tricuspid insufficiency	0.111	0.889	0.000
I11 Hypertensive heart disease	0.103	0.897	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.098	0.902	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.098	0.902	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.098	0.902	0.000
I15 Secondary hypertension	0.091	0.908	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.091	0.909	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.910	0.090
C85.1 B-cell lymphoma, unspecified	0.000	0.911	0.089
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.912	0.088
I98 Other disorders of circulatory system in diseases classified elsewhere	0.086	0.914	0.001
I97.9 Postprocedural disorder of circulatory system, unspecified	0.082	0.918	0.000
I97.0 Postcardiotomy syndrome	0.082	0.918	0.000
I74 Arterial embolism and thrombosis	0.081	0.919	0.000
I97.1 Other functional disturbances following cardiac surgery	0.078	0.921	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.077	0.923	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.076	0.924	0.000
I73 Other peripheral vascular diseases	0.074	0.926	0.000
I73.9 Peripheral vascular disease, unspecified	0.073	0.927	0.000
I15.2 Hypertension secondary to endocrine disorders	0.071	0.928	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.071	0.929	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.071	0.929	0.000
H91.9 Hearing loss, unspecified	0.071	0.929	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.070	0.930	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.068	0.932	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.067	0.933	0.000
I60-I69 Cerebrovascular diseases	0.066	0.934	0.000
I15.8 Other secondary hypertension	0.066	0.934	0.000
I15.0 Renovascular hypertension	0.066	0.934	0.000
I69 Sequelae of cerebrovascular disease	0.064	0.936	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.064	0.936	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.937	0.063
C85.0 Lymphosarcoma	0.000	0.937	0.063
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.062	0.938	0.001
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.062	0.938	0.001
I98.0 Cardiovascular syphilis	0.062	0.938	0.001
I74.0 Embolism and thrombosis of abdominal aorta	0.061	0.939	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.939	0.061
I74.9 Embolism and thrombosis of unspecified artery	0.061	0.939	0.000
I70 Atherosclerosis	0.060	0.939	0.000
I74.8 Embolism and thrombosis of other arteries	0.060	0.940	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.059	0.941	0.000
I69.3 Sequelae of cerebral infarction	0.059	0.941	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.059	0.941	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.058	0.942	0.001
I21 Acute myocardial infarction	0.057	0.943	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.944	0.056
I69.0 Sequelae of subarachnoid haemorrhage	0.055	0.945	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.946	0.054
I73.1 Thromboangiitis obliterans [Buerger]	0.053	0.946	0.000
I12.9 Hypertensive renal disease without renal failure	0.053	0.947	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.947	0.053
I74.5 Embolism and thrombosis of iliac artery	0.053	0.947	0.000
C83.3 Large cell (diffuse)	0.000	0.948	0.052
I69.1 Sequelae of intracerebral haemorrhage	0.052	0.948	0.000
I78 Diseases of capillaries	0.052	0.948	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.950	0.050
I15.9 Seconday hypertension, unspecified	0.049	0.950	0.001
I64 Stroke, not specified as haemorrhage or infarction	0.050	0.950	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.048	0.952	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.048	0.952	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.048	0.952	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.048	0.952	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.048	0.952	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.047	0.952	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.047	0.953	0.000
C82.0 Small cleaved cell, follicular	0.000	0.953	0.047
I15.1 Hypertension secondary to other renal disorders	0.046	0.953	0.000
I73.8 Other specified peripheral vascular diseases	0.046	0.953	0.000
I79.1 Aortitis in diseases classified elsewhere	0.046	0.954	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.046	0.954	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.046	0.954	0.000
C88 Malignant immunoproliferative diseases	0.000	0.955	0.045
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.956	0.044
I70.9 Generalised and unspecified atherosclerosis	0.043	0.956	0.000
I70.8 Atherosclerosis of other arteries	0.043	0.956	0.000
I78.9 Disease of capillaries, unspecified	0.043	0.957	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.042	0.958	0.000
C81 Hodgkin's disease	0.000	0.958	0.042
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.042	0.958	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.041	0.959	0.000
I70.0 Atherosclerosis of aorta	0.041	0.959	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.041	0.959	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.959	0.041
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.959	0.041
C94 Other leukaemias of specified cell type	0.000	0.959	0.041
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.960	0.040
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.960	0.040
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.040	0.960	0.000
C82.6 Cutaneous follicle centre lymphoma	0.000	0.961	0.039
C82.5 Diffuse follicle centre lymphoma	0.000	0.961	0.039
C82.3 Follicular lymphoma grade IIIa	0.000	0.961	0.039
I21.2 Acute transmural myocardial infarction of other sites	0.039	0.961	0.000
C86 Other specified types of T/NK-cell lymphoma	0.000	0.961	0.039
I66.0 Occlusion and stenosis of middle cerebral artery	0.038	0.961	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.038	0.962	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.962	0.038
C83.6 Undifferentiated (diffuse)	0.000	0.962	0.038
C83.5 Lymphoblastic (diffuse)	0.000	0.962	0.038
C83.4 Immunoblastic (diffuse)	0.000	0.962	0.038
C83.2 Mixed small and large cell (diffuse)	0.000	0.962	0.038
I21.3 Acute transmural myocardial infarction of unspecified site	0.038	0.962	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.038	0.962	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.038	0.962	0.000
I78.1 Naevus, nonneoplastic	0.038	0.962	0.000
C82.2 Large cell, follicular	0.000	0.963	0.037
C83.0 Small cell (diffuse)	0.000	0.963	0.037
C93 Monocytic leukaemia	0.000	0.963	0.037
H91 Other hearing loss	0.037	0.963	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.964	0.036
I70.1 Atherosclerosis of renal artery	0.035	0.964	0.000
C83.1 Small cleaved cell (diffuse)	0.000	0.965	0.035
C95 Leukaemia of unspecified cell type	0.000	0.965	0.035
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.000	0.965	0.035
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.035	0.965	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.035	0.965	0.000
I65.1 Occlusion and stenosis of basilar artery	0.035	0.965	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.965	0.035
I66.8 Occlusion and stenosis of other cerebral artery	0.035	0.965	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.035	0.965	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.035	0.965	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.035	0.965	0.000
I95 Hypotension	0.035	0.965	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.034	0.965	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.034	0.966	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.034	0.966	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.034	0.966	0.000
I68.0 Cerebral amyloid angiopathy	0.034	0.966	0.000
C81.9 Hodgkin's disease, unspecified	0.000	0.966	0.034
C82.4 Follicular lymphoma grade IIIb	0.000	0.967	0.033
C81.0 Lymphocytic predominance	0.000	0.967	0.033
C88.9 Malignant immunoproliferative disease, unspecified	0.000	0.967	0.032
C88.7 Other malignant immunoproliferative diseases	0.000	0.967	0.032
C88.3 Immunoproliferative small intestinal disease	0.000	0.967	0.032
C88.2 Gamma heavy chain disease	0.000	0.967	0.032
C88.1 Alpha heavy chain disease	0.000	0.967	0.032
I95.8 Other hypotension	0.032	0.968	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.031	0.968	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.031	0.968	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.031	0.968	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.031	0.969	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.031	0.969	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.031	0.969	0.000
I72 Other aneurysm	0.030	0.970	0.000
C81.7 Other Hodgkin's disease	0.000	0.970	0.030
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.970	0.030
C81.3 Lymphocytic depletion	0.000	0.970	0.030
I78.8 Other diseases of capillaries	0.030	0.970	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.030	0.970	0.000
H91.8 Other specified hearing loss	0.029	0.970	0.000
C83.7 Burkitt's tumour	0.000	0.971	0.029
C94.7 Other specified leukaemias	0.000	0.971	0.029
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.000	0.971	0.029
C94.5 Acute myelofibrosis	0.000	0.971	0.029
C94.4 Acute panmyelosis	0.000	0.971	0.029
C94.3 Mast cell leukaemia	0.000	0.971	0.029
C94.2 Acute megakaryoblastic leukaemia	0.000	0.971	0.029
C94.1 Chronic erythraemia	0.000	0.971	0.029
C94.0 Acute erythraemia and erythroleukaemia	0.000	0.971	0.029
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.971	0.029
C96.8 Histiocytic sarcoma	0.000	0.971	0.029
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.971	0.029
C96.6 Unifocal Langerhans-cell histiocytosis	0.000	0.971	0.029
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.000	0.971	0.029
C96.4 Sarcoma of dendritic cells (accessory cells)	0.000	0.971	0.029
C96.3 True histiocytic lymphoma	0.000	0.971	0.029
C96.2 Malignant mast cell tumour	0.000	0.971	0.029
C96.1 Malignant histiocytosis	0.000	0.971	0.029
C96.0 Letterer-Siwe disease	0.000	0.971	0.029
C84.4 Peripheral T-cell lymphoma	0.000	0.971	0.029
C81.1 Nodular sclerosis	0.000	0.971	0.029
C90.2 Plasmacytoma, extramedullary	0.000	0.971	0.029
I65.2 Occlusion and stenosis of carotid artery	0.029	0.971	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.000	0.972	0.028
C86.4 Blastic NK-cell lymphoma	0.000	0.972	0.028
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.000	0.972	0.028
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.000	0.972	0.028
C86.1 Hepatosplenic T-cell lymphoma	0.000	0.972	0.028
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.000	0.972	0.028
H91.3 Deaf mutism, not elsewhere classified	0.027	0.973	0.000
C90.1 Plasma cell leukaemia	0.000	0.973	0.027
I70.00 Atherosclerosis of aorta (without gangrene)	0.027	0.973	0.000
C90.0 Multiple myeloma	0.000	0.973	0.027
C93.9 Monocytic leukaemia, unspecified	0.000	0.973	0.027
C93.7 Other monocytic leukaemia	0.000	0.973	0.027
C93.3 Juvenile myelomonocytic leukaemia	0.000	0.973	0.027
C93.2 Subacute monocytic leukaemia	0.000	0.973	0.027
C93.0 Acute monocytic leukaemia	0.000	0.973	0.027
H91.0 Ototoxic hearing loss	0.027	0.973	0.000
H91.2 Sudden idiopathic hearing loss	0.027	0.973	0.000
H91.1 Presbycusis	0.026	0.974	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.000	0.974	0.026
C84.8 Cutaneous T-cell lymphoma, unspecified	0.000	0.974	0.026
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.000	0.974	0.026
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.000	0.974	0.026
C84.3 Lymphoepithelioid lymphoma	0.000	0.974	0.026
C84.2 T-zone lymphoma	0.000	0.974	0.026
C84.1 Sezary's diease	0.000	0.974	0.026
C86.5 Angioimmunoblastic T-cell lymphoma	0.000	0.974	0.026
I70.11 Atherosclerosis of renal artery (with gangrene)	0.025	0.974	0.000
C81.2 Mixed cellularity	0.000	0.974	0.025
C95.7 Other leukaemia of unspecified cell type	0.000	0.974	0.025
C95.2 Subacute leukaemia of unspecified cell type	0.000	0.974	0.025
C95.1 Chronic leukaemia of unspecified cell type	0.000	0.974	0.025
C95.0 Acute leukaemia of unspecified cell type	0.000	0.974	0.025
I62 Other nontraumatic intracranial haemorrhage	0.025	0.975	0.000
C90.3 Solitary plasmacytoma	0.000	0.975	0.025
I60 Subarachnoid haemorrhage	0.024	0.976	0.000
C91 Lymphoid leukaemia	0.000	0.976	0.024
I95.0 Idiopathic hypotension	0.023	0.976	0.000
C93.1 Chronic monocytic leukaemia	0.000	0.977	0.023
I72.8 Aneurysm of other specified arteries	0.023	0.977	0.000
C84.0 Mycosis fungoides	0.000	0.977	0.022
I72.6 Aneurysm and dissection of vertebral artery	0.022	0.978	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.022	0.978	0.000
I72.1 Aneurysm of artery of upper extremity	0.022	0.978	0.000
C84.5 Other and unspecified T-cell lymphomas	0.000	0.978	0.021
I21.4 Acute subendocardial myocardial infarction	0.022	0.978	0.000
D24 Benign neoplasm of breast	0.021	0.979	0.000
C92 Myeloid leukaemia	0.000	0.979	0.021
I21.1 Acute transmural myocardial infarction of inferior wall	0.021	0.979	0.000
I72.4 Aneurysm of artery of lower extremity	0.021	0.979	0.000
I72.0 Aneurysm of carotid artery	0.020	0.980	0.000
C95.9 Leukaemia, unspecified	0.000	0.980	0.020
I63 Cerebral infarction	0.020	0.980	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.019	0.980	0.001
I60.8 Other subarachnoid haemorrhage	0.020	0.980	0.000
I72.2 Aneurysm of renal artery	0.019	0.981	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.018	0.981	0.000
I62.1 Nontraumatic extradural haemorrhage	0.018	0.981	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.018	0.982	0.000
C91.5 Adult T-cell leukaemia	0.000	0.982	0.018
I77 Other disorders of arteries and arterioles	0.018	0.982	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.017	0.982	0.001
I98.2 Oesophageal varices in diseases classified elsewhere	0.016	0.982	0.001
I60.5 Subarachnoid haemorrhage from vertebral artery	0.017	0.983	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.017	0.983	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.983	0.017
C91.7 Other lymphoid leukaemia	0.000	0.983	0.017
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.983	0.017
C91.3 Prolymphocytic leukaemia	0.000	0.983	0.017
C91.2 Subacute lymphocytic leukaemia	0.000	0.983	0.017
C91.0 Acute lymphoblastic leukaemia	0.000	0.983	0.017
I60.4 Subarachnoid haemorrhage from basilar artery	0.017	0.983	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.017	0.983	0.000
I72.9 Aneurysm of unspecified site	0.016	0.983	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.017	0.983	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.016	0.984	0.000
C91.9 Lymphoid leukaemia, unspecified	0.000	0.984	0.016
I77.6 Arteritis, unspecified	0.015	0.985	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.985	0.015
C92.7 Other myeloid leukaemia	0.000	0.985	0.015
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.985	0.015
C92.5 Acute myelomonocytic leukaemia	0.000	0.985	0.015
C92.3 Myeloid sarcoma	0.000	0.985	0.015
C92.2 Subacute myeloid leukaemia	0.000	0.985	0.015
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.015	0.985	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.015	0.985	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.014	0.986	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.014	0.986	0.000
I72.3 Aneurysm of iliac artery	0.014	0.986	0.000
C92.9 Myeloid leukaemia, unspecified	0.000	0.986	0.014
C92.4 Acute promyelocytic leukaemia	0.000	0.986	0.014
I21.9 Acute myocardial infarction, unspecified	0.014	0.986	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.000	0.986	0.014
I77.2 Rupture of artery	0.013	0.986	0.000
C91.4 Hairy-cell leukaemia	0.000	0.987	0.013
I77.5 Necrosis of artery	0.013	0.987	0.000
I77.4 Coeliac artery compression syndrome	0.013	0.987	0.000
I77.3 Arterial fibromuscular dysplasia	0.013	0.987	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.013	0.987	0.000
I71 Aortic aneurysm and dissection	0.013	0.987	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.012	0.987	0.000
C92.1 Chronic myeloid leukaemia	0.000	0.988	0.012
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.012	0.988	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.011	0.989	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.990	0.010
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.010	0.990	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.010	0.990	0.000
I73.0 Raynaud's syndrome	0.010	0.990	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.009	0.990	0.000
I63.8 Other cerebral infarction	0.009	0.990	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.009	0.990	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.009	0.991	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.009	0.991	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.009	0.991	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.009	0.991	0.000
I71.0 Dissection of aorta [any part]	0.009	0.991	0.000
I95.2 Hypotension due to drugs	0.008	0.991	0.001
L89 Decubitus ulcer	0.009	0.991	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.009	0.991	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.008	0.992	0.000
L89.1 Stage II decubitus ulcer	0.008	0.992	0.000
I34.0 Mitral (valve) insufficiency	0.008	0.992	0.000
I77.8 Other specified disorders of arteries and arterioles	0.008	0.992	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.008	0.992	0.000
C92.0 Acute myeloid leukaemia	0.000	0.992	0.007
F25.9 Schizoaffective disorder, unspecified	0.007	0.993	0.000
F25 Schizoaffective disorders	0.007	0.993	0.000
F29 Unspecified nonorganic psychosis	0.007	0.993	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.007	0.993	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.007	0.993	0.000
L89.2 Stage III decubitus ulcer	0.007	0.993	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.007	0.993	0.000
I77.0 Arteriovenous fistula, acquired	0.006	0.993	0.001
I50.9 Heart failure, unspecified	0.007	0.993	0.000
I61 Intracerebral haemorrhage	0.007	0.993	0.000
L89.3 Stage IV decubitus ulcer	0.006	0.994	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.006	0.994	0.000
F25.1 Schizoaffective disorder, depressive type	0.006	0.994	0.000
F25.2 Schizoaffective disorder, mixed type	0.006	0.994	0.000
I50 Heart failure	0.006	0.994	0.000
I34 Nonrheumatic mitral valve disorders	0.006	0.994	0.000
I30-I52 Other forms of heart disease	0.006	0.994	0.000
I50.0 Congestive heart failure	0.006	0.994	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.006	0.994	0.000
F25.0 Schizoaffective disorder, manic type	0.005	0.994	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.005	0.994	0.000
F25.8 Other schizoaffective disorders	0.005	0.994	0.000
F23 Acute and transient psychotic disorders	0.005	0.994	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.005	0.995	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.005	0.995	0.000
S22.30 Fracture of rib (closed)	0.005	0.995	0.000
F28 Other nonorganic psychotic disorders	0.005	0.995	0.000
F24 Induced delusional disorder	0.005	0.995	0.000
F21 Schizotypal disorder	0.005	0.995	0.000
F52.2 Failure of genital response	0.000	0.995	0.005
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.005	0.995	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.005	0.995	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.005	0.995	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.004	0.995	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.004	0.995	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.004	0.995	0.000
I52 Other heart disorders in diseases classified elsewhere	0.004	0.996	0.000
I48 Atrial fibrillation and flutter	0.004	0.996	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.004	0.996	0.000
I41 Myocarditis in diseases classified elsewhere	0.004	0.996	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.004	0.996	0.000
I32 Pericarditis in diseases classified elsewhere	0.004	0.996	0.000
I38 Endocarditis, valve unspecified	0.004	0.996	0.000
I77.1 Stricture of artery	0.004	0.996	0.000
I40 Acute myocarditis	0.004	0.996	0.000
I67 Other cerebrovascular diseases	0.004	0.996	0.000
Y84.1 Kidney dialysis	0.004	0.996	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.004	0.996	0.000
R26 Abnormalities of gait and mobility	0.004	0.996	0.000
I42.0 Dilated cardiomyopathy	0.004	0.996	0.000
I49 Other cardiac arrhythmias	0.004	0.996	0.000
F23.8 Other acute and transient psychotic disorders	0.004	0.996	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.004	0.996	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.004	0.996	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.004	0.996	0.000
H43.3 Other vitreous opacities	0.000	0.996	0.004
I34.8 Other nonrheumatic mitral valve disorders	0.004	0.996	0.000
F22 Persistent delusional disorders	0.004	0.996	0.000
A49.0 Staphylococcal infection, unspecified	0.000	0.996	0.004
I49.9 Cardiac arrhythmia, unspecified	0.004	0.996	0.000
I36 Nonrheumatic tricuspid valve disorders	0.004	0.996	0.000
I49.4 Other and unspecified premature depolarisation	0.004	0.996	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.004	0.996	0.000
I61.8 Other intracerebral haemorrhage	0.004	0.996	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.004	0.996	0.000
O72.1 Other immediate postpartum haemorrhage	0.004	0.996	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.000	0.996	0.004
I42 Cardiomyopathy	0.004	0.996	0.000
I49.1 Atrial premature depolarisation	0.004	0.996	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.003	0.996	0.000
I46 Cardiac arrest	0.004	0.996	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.003	0.996	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.004	0.996	0.000
O73.0 Retained placenta, without haemorrhage	0.004	0.996	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.004	0.996	0.000
D51 Vitamin B12 deficiency anaemia	0.004	0.996	0.000
S22.3 Fracture of rib	0.004	0.996	0.000
F20 Schizophrenia	0.004	0.996	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.004	0.996	0.000
I37 Pulmonary valve disorders	0.003	0.996	0.000
I49.0 Ventricular fibrillation and flutter	0.003	0.996	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.003	0.997	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.003	0.997	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.003	0.997	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.003	0.997	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.003	0.997	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.003	0.997	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.003	0.997	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.003	0.997	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.003	0.997	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.003	0.997	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.003	0.997	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.003	0.997	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.003	0.997	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.003	0.997	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.003	0.997	0.000
I48.4 Atypical atrial flutter	0.003	0.997	0.000
I48.3 Typical atrial flutter	0.003	0.997	0.000
I48.2 Chronic atrial fibrillation	0.003	0.997	0.000
I48.1 Persistent atrial fibrillation	0.003	0.997	0.000
I48.0 Paroxysmal atrial fibrillation	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations