TreeWAS – Variant ID: rs46522

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.760	0.240	0.000
I10-I15 Hypertensive diseases	0.237	0.763	0.000
E11 Non-insulin-dependent diabetes mellitus	0.234	0.766	0.000
E11.3 With ophthalmic complications	0.233	0.767	0.000
E11.9 Without complications	0.231	0.769	0.000
E10 Insulin-dependent diabetes mellitus	0.226	0.774	0.000
E10.3 With ophthalmic complications	0.223	0.777	0.000
E10-E14 Diabetes mellitus	0.218	0.782	0.000
E11.1 With ketoacidosis	0.217	0.783	0.000
E10.1 With ketoacidosis	0.196	0.804	0.000
E11.0 With coma	0.185	0.815	0.000
E10.2 With renal complications	0.182	0.818	0.000
E10.9 Without complications	0.181	0.819	0.000
E11.8 With unspecified complications	0.177	0.823	0.000
E10.4 With neurological complications	0.176	0.824	0.000
E10.7 With multiple complications	0.174	0.826	0.000
E10.5 With peripheral circulatory complications	0.174	0.826	0.000
E10.6 With other specified complications	0.171	0.829	0.000
I11 Hypertensive heart disease	0.169	0.831	0.000
I15 Secondary hypertension	0.166	0.834	0.000
I13 Hypertensive heart and renal disease	0.165	0.834	0.000
E11.7 With multiple complications	0.163	0.837	0.000
E10.8 With unspecified complications	0.157	0.843	0.000
E12 Malnutrition-related diabetes mellitus	0.156	0.843	0.000
E11.6 With other specified complications	0.154	0.846	0.000
I12 Hypertensive renal disease	0.143	0.857	0.000
I15.2 Hypertension secondary to endocrine disorders	0.137	0.863	0.000
E10.0 With coma	0.131	0.868	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.128	0.872	0.000
I15.0 Renovascular hypertension	0.126	0.873	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.119	0.881	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.119	0.881	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.119	0.881	0.000
E13 Other specified diabetes mellitus	0.116	0.883	0.000
E11.2 With renal complications	0.115	0.885	0.000
I15.8 Other secondary hypertension	0.115	0.885	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.114	0.885	0.000
E12.9 Without complications	0.112	0.887	0.000
E12.8 With unspecified complications	0.112	0.887	0.000
E12.7 With multiple complications	0.112	0.887	0.000
E12.6 With other specified complications	0.112	0.887	0.000
E12.5 With peripheral circulatory complications	0.112	0.887	0.000
E12.4 With neurological complications	0.112	0.887	0.000
E12.3 With ophthalmic complications	0.112	0.887	0.000
E12.2 With renal complications	0.112	0.887	0.000
E12.1 With ketoacidosis	0.112	0.887	0.000
E12.0 With coma	0.112	0.887	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.112	0.888	0.000
I15.1 Hypertension secondary to other renal disorders	0.103	0.897	0.000
E11.4 With neurological complications	0.101	0.899	0.000
I15.9 Seconday hypertension, unspecified	0.099	0.901	0.000
I12.9 Hypertensive renal disease without renal failure	0.099	0.901	0.000
E11.5 With peripheral circulatory complications	0.092	0.908	0.000
E14 Unspecified diabetes mellitus	0.087	0.913	0.000
E13.8 With unspecified complications	0.084	0.916	0.000
E13.7 With multiple complications	0.084	0.916	0.000
E13.6 With other specified complications	0.084	0.916	0.000
E13.5 With peripheral circulatory complications	0.084	0.916	0.000
E13.4 With neurological complications	0.084	0.916	0.000
E13.2 With renal complications	0.084	0.916	0.000
E13.1 With ketoacidosis	0.084	0.916	0.000
E13.0 With coma	0.084	0.916	0.000
E13.3 With ophthalmic complications	0.083	0.917	0.000
I12.0 Hypertensive renal disease with renal failure	0.083	0.917	0.000
E14.3 With ophthalmic complications	0.075	0.925	0.000
E14.8 With unspecified complications	0.071	0.929	0.000
E14.7 With multiple complications	0.062	0.937	0.000
E14.0 With coma	0.062	0.937	0.000
E14.6 With other specified complications	0.061	0.939	0.000
E14.1 With ketoacidosis	0.060	0.940	0.000
E14.2 Withrenal complications	0.056	0.944	0.000
E14.5 With peripheral circulatory complications	0.052	0.948	0.000
E13.9 Without complications	0.045	0.954	0.000
E14.4 With neurological complications	0.043	0.957	0.000
Z53.0 Procedure not carried out because of contraindication	0.031	0.969	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.024	0.976	0.000
E20-E35 Disorders of other endocrine glands	0.021	0.979	0.000
E23 Hypofunction and other disorders of pituitary gland	0.021	0.979	0.000
E26 Hyperaldosteronism	0.020	0.980	0.000
E23.2 Diabetes insipidus	0.020	0.980	0.000
E26.0 Primary hyperaldosteronism	0.019	0.981	0.000
E50-E64 Other nutritional deficiencies	0.018	0.982	0.000
E27 Other disorders of adrenal gland	0.018	0.982	0.000
E65-E68 Obesity and other hyperalimentation	0.017	0.983	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.017	0.983	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.017	0.983	0.000
E20 Hypoparathyroidism	0.017	0.983	0.000
E23.7 Disorder of pituitary gland, unspecified	0.016	0.984	0.000
E29 Testicular dysfunction	0.016	0.984	0.000
E32 Diseases of thymus	0.016	0.984	0.000
E55 Vitamin D deficiency	0.016	0.984	0.000
E26.9 Hyperaldosteronism, unspecified	0.016	0.984	0.000
E27.2 Addisonian crisis	0.016	0.984	0.000
E25 Adrenogenital disorders	0.016	0.984	0.000
E23.6 Other disorders of pituitary gland	0.016	0.984	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.015	0.984	0.000
E30 Disorders of puberty, not elsewhere classified	0.015	0.984	0.000
E27.9 Disorder of adrenal gland, unspecified	0.015	0.985	0.000
E23.1 Drug-induced hypopituitarism	0.015	0.985	0.000
E28 Ovarian dysfunction	0.015	0.985	0.000
E26.8 Other hyperaldosteronism	0.015	0.985	0.000
E26.1 Secondary hyperaldosteronism	0.015	0.985	0.000
E40-E46 Malnutrition	0.014	0.986	0.000
E58 Dietary calcium deficiency	0.014	0.986	0.000
E55.9 Vitamin D deficiency, unspecified	0.014	0.986	0.000
E53 Deficiency of other B group vitamins	0.014	0.986	0.000
E27.8 Other specified disorders of adrenal gland	0.014	0.986	0.000
E31 Polyglandular dysfunction	0.014	0.986	0.000
E63 Other nutritional deficiencies	0.014	0.986	0.000
E23.0 Hypopituitarism	0.014	0.986	0.000
E20.9 Hypoparathyroidism, unspecified	0.014	0.986	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.013	0.987	0.000
E50 Vitamin A deficiency	0.013	0.987	0.000
E60 Dietary zinc deficiency	0.013	0.987	0.000
E59 Dietary selenium deficiency	0.013	0.987	0.000
E54 Ascorbic acid deficiency	0.013	0.987	0.000
E52 Niacin deficiency [pellagra]	0.013	0.987	0.000
E27.5 Adrenomedullary hyperfunction	0.013	0.987	0.000
E27.0 Other adrenocortical overactivity	0.013	0.987	0.000
E29.1 Testicular hypofunction	0.013	0.987	0.000
E65 Localised adiposity	0.013	0.987	0.000
E27.1 Primary adrenocortical insufficiency	0.013	0.987	0.000
E67 Other hyperalimentation	0.013	0.987	0.000
E68 Sequelae of hyperalimentation	0.013	0.987	0.000
E15 Nondiabetic hypoglycaemic coma	0.012	0.987	0.000
E32.8 Other diseases of thymus	0.012	0.988	0.000
E66 Obesity	0.012	0.988	0.000
E24 Cushing's syndrome	0.012	0.988	0.000
E16 Other disorders of pancreatic internal secretion	0.012	0.988	0.000
E20.8 Other hypoparathyroidism	0.012	0.988	0.000
E20.1 Pseudohypoparathyroidism	0.012	0.988	0.000
E20.0 Idiopathic hypoparathyroidism	0.012	0.988	0.000
E51 Thiamine deficiency	0.012	0.988	0.000
E56 Other vitamin deficiencies	0.012	0.988	0.000
E29.8 Other testicular dysfunction	0.012	0.988	0.000
E29.0 Testicular hyperfunction	0.012	0.988	0.000
E32.9 Disease of thymus, unspecified	0.012	0.988	0.000
E32.1 Abscess of thymus	0.012	0.988	0.000
E32.0 Persistent hyperplasia of thymus	0.012	0.988	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.988	0.012
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.011	0.988	0.000
E55.0 Rickets, active	0.011	0.988	0.000
E25.9 Adrenogenital disorder, unspecified	0.011	0.988	0.000
E25.8 Other adrenogenital disorders	0.011	0.988	0.000
E29.9 Testicular dysfunction, unspecified	0.011	0.988	0.000
E30.9 Disorder of puberty, unspecified	0.011	0.989	0.000
E30.8 Other disorders of puberty	0.011	0.989	0.000
E30.1 Precocious puberty	0.011	0.989	0.000
E30.0 Delayed puberty	0.011	0.989	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.011	0.989	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.011	0.989	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.011	0.989	0.000
E53.9 Vitamin B deficiency, unspecified	0.011	0.989	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.989	0.011
E66.9 Obesity, unspecified	0.011	0.989	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.011	0.989	0.000
E34 Other endocrine disorders	0.011	0.989	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.011	0.989	0.000
E28.9 Ovarian dysfunction, unspecified	0.011	0.989	0.000
E28.8 Other ovarian dysfunction	0.011	0.989	0.000
E28.1 Androgen excess	0.011	0.989	0.000
E28.0 Oestrogen excess	0.011	0.989	0.000
S40-S49 Injuries to the shoulder and upper arm	0.000	0.989	0.011
E28.3 Primary ovarian failure	0.011	0.989	0.000
E28.2 Polycystic ovarian syndrome	0.011	0.989	0.000
E63.9 Nutritional deficiency, unspecified	0.010	0.989	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.010	0.989	0.000
E45 Retarded development following protein-energy malnutrition	0.010	0.989	0.000
E43 Unspecified severe protein-energy malnutrition	0.010	0.989	0.000
E42 Marasmic kwashiorkor	0.010	0.989	0.000
E41 Nutritional marasmus	0.010	0.989	0.000
E40 Kwashiorkor	0.010	0.989	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.011	0.989	0.000
R60.0 Localised oedema	0.011	0.989	0.000
E14.9 Without complications	0.011	0.989	0.000
E53.1 Pyridoxine deficiency	0.010	0.990	0.000
E53.0 Riboflavin deficiency	0.010	0.990	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.990	0.010
E31.9 Polyglandular dysfunction, unspecified	0.010	0.990	0.000
E31.8 Other polyglandular dysfunction	0.010	0.990	0.000
E31.1 Polyglandular hyperfunction	0.010	0.990	0.000
E53.8 Deficiency of other specified B group vitamins	0.010	0.990	0.000
E63.8 Other specified nutritional deficiencies	0.010	0.990	0.000
E63.1 Imbalance of constituents of food intake	0.010	0.990	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.010	0.990	0.000
E24.9 Cushing's syndrome, unspecified	0.010	0.990	0.000
S43.1 Dislocation of acromioclavicular joint	0.000	0.990	0.010
E50.9 Vitamin A deficiency, unspecified	0.009	0.990	0.000
E50.8 Other manifestations of vitamin A deficiency	0.009	0.990	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.009	0.990	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.009	0.990	0.000
E50.5 Vitamin A deficiency with night blindness	0.009	0.990	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.009	0.990	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.009	0.990	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.009	0.990	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.009	0.990	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.009	0.990	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.009	0.990	0.000
E64.8 Sequelae of other nutritional deficiencies	0.009	0.990	0.000
E64.3 Sequelae of rickets	0.009	0.990	0.000
E64.2 Sequelae of vitamin C deficiency	0.009	0.990	0.000
E64.1 Sequelae of vitamin A deficiency	0.009	0.990	0.000
E64.0 Sequelae of protein-energy malnutrition	0.009	0.990	0.000
E66.0 Obesity due to excess calories	0.010	0.990	0.000
S41 Open wound of shoulder and upper arm	0.000	0.990	0.010
S41.1 Open wound of upper arm	0.000	0.990	0.010
S40 Superficial injury of shoulder and upper arm	0.000	0.991	0.009
E67.8 Other specified hyperalimentation	0.009	0.991	0.000
E67.3 Hypervitaminosis D	0.009	0.991	0.000
E67.2 Megavitamin-B6 syndrome	0.009	0.991	0.000
E67.1 Hypercarotenaemia	0.009	0.991	0.000
E67.0 Hypervitaminosis A	0.009	0.991	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.991	0.009
E66.1 Drug-induced obesity	0.009	0.991	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.009	0.991	0.000
E24.3 Ectopic ACTH syndrome	0.009	0.991	0.000
E24.1 Nelson's syndrome	0.009	0.991	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.009	0.991	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.009	0.991	0.000
E16.4 Abnormal secretion of gastrin	0.009	0.991	0.000
E16.3 Increased secretion of glucagon	0.009	0.991	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.000	0.991	0.009
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.009	0.991	0.000
E51.9 Thiamine deficiency, unspecified	0.009	0.991	0.000
E51.8 Other manifestations of thiamine deficiency	0.009	0.991	0.000
E51.1 Beriberi	0.009	0.991	0.000
S42 Fracture of shoulder and upper arm	0.000	0.991	0.009
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.000	0.991	0.009
K65.8 Other peritonitis	0.009	0.991	0.000
E56.9 Vitamin deficiency, unspecified	0.009	0.991	0.000
E56.8 Deficiency of other vitamins	0.009	0.991	0.000
E56.0 Deficiency of vitamin E	0.009	0.991	0.000
E24.8 Other Cushing's syndrome	0.009	0.991	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.000	0.991	0.009
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.991	0.009
E34.3 Short stature, not elsewhere classified	0.009	0.991	0.000
E31.0 Autoimmune polyglandular failure	0.008	0.991	0.000
S43.0 Dislocation of shoulder joint	0.000	0.991	0.009
S46.1 Injury of muscle and tendon of long head of biceps	0.000	0.991	0.008
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.000	0.992	0.008
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.000	0.992	0.008
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.000	0.992	0.008
E34.5 Androgen resistance syndrome	0.008	0.992	0.000
E34.4 Constitutional tall stature	0.008	0.992	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.008	0.992	0.000
E34.1 Other hypersecretion of intestinal hormones	0.008	0.992	0.000
E51.2 Wernicke's encephalopathy	0.008	0.992	0.000
S48 Traumatic amputation of shoulder and upper arm	0.000	0.992	0.008
S44 Injury of nerves at shoulder and upper arm level	0.000	0.992	0.008
S47 Crushing injury of shoulder and upper arm	0.000	0.992	0.008
S62.61 Fracture of other finger (open)	0.000	0.992	0.008
S45 Injury of blood vessels at shoulder and upper arm level	0.000	0.992	0.008
E44.1 Mild protein-energy malnutrition	0.008	0.992	0.000
E44.0 Moderate protein-energy malnutrition	0.008	0.992	0.000
S46.3 Injury of muscle and tendon of triceps	0.000	0.992	0.008
E56.1 Deficiency of vitamin K	0.007	0.992	0.000
S42.4 Fracture of lower end of humerus	0.000	0.992	0.008
S43.2 Dislocation of sternoclavicular joint	0.000	0.992	0.008
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.000	0.992	0.008
S43.6 Sprain and strain of sternoclavicular joint	0.000	0.992	0.008
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.000	0.992	0.008
E24.0 Pituitary-dependent Cushing's disease	0.007	0.992	0.000
I44.1 Atrioventricular block, second degree	0.000	0.992	0.008
E22 Hyperfunction of pituitary gland	0.007	0.992	0.000
E46 Unspecified protein-energy malnutrition	0.007	0.992	0.000
E16.2 Hypoglycaemia, unspecified	0.008	0.992	0.000
E16.1 Other hypoglycaemia	0.007	0.992	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.000	0.993	0.007
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.007	0.993	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.000	0.993	0.007
E61 Deficiency of other nutrient elements	0.007	0.993	0.000
S40.0 Contusion of shoulder and upper arm	0.000	0.993	0.007
E24.2 Drug-induced Cushing's syndrome	0.007	0.993	0.000
E21.2 Other hyperparathyroidism	0.007	0.993	0.000
E34.0 Carcinoid syndrome	0.007	0.993	0.000
N81.4 Uterovaginal prolapse, unspecified	0.000	0.993	0.007
E34.8 Other specified endocrine disorders	0.007	0.993	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.000	0.993	0.007
S43.4 Sprain and strain of shoulder joint	0.000	0.993	0.007
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.007	0.993	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.000	0.993	0.007
E66.8 Other obesity	0.007	0.993	0.000
E34.9 Endocrine disorder, unspecified	0.007	0.993	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.993	0.007
S42.40 Fracture of lower end of humerus (closed)	0.000	0.993	0.007
E21.4 Other specified disorders of parathyroid gland	0.007	0.993	0.000
S62.60 Fracture of other finger (closed)	0.000	0.993	0.007
S49.7 Multiple injuries of shoulder and upper arm	0.000	0.993	0.006
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.000	0.993	0.006
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.993	0.006
S42.1 Fracture of scapula	0.000	0.993	0.007
E21.5 Disorder of parathyroid gland, unspecified	0.006	0.993	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.006	0.993	0.000
S41.0 Open wound of shoulder	0.000	0.993	0.006
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.994	0.006
S42.3 Fracture of shaft of humerus	0.000	0.994	0.006
S62.6 Fracture of other finger	0.000	0.994	0.006
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.000	0.994	0.006
S44.8 Injury of other nerves at shoulder and upper arm level	0.000	0.994	0.006
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.000	0.994	0.006
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.000	0.994	0.006
S44.4 Injury of musculocutaneous nerve	0.000	0.994	0.006
S44.3 Injury of axillary nerve	0.000	0.994	0.006
S44.2 Injury of radial nerve at upper arm level	0.000	0.994	0.006
S44.1 Injury of median nerve at upper arm level	0.000	0.994	0.006
S44.0 Injury of ulnar nerve at upper arm level	0.000	0.994	0.006
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.000	0.994	0.006
S48.1 Traumatic amputation at level between shoulder and elbow	0.000	0.994	0.006
S48.0 Traumatic amputation at shoulder joint	0.000	0.994	0.006
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.000	0.994	0.006
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.000	0.994	0.006
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.000	0.994	0.006
S45.3 Injury of superficial vein at shoulder and upper arm level	0.000	0.994	0.006
S45.2 Injury of axillary or brachial vein	0.000	0.994	0.006
S45.1 Injury of brachial artery	0.000	0.994	0.006
S45.0 Injury of axillary artery	0.000	0.994	0.006
D86.9 Sarcoidosis, unspecified	0.000	0.994	0.006
F29 Unspecified nonorganic psychosis	0.000	0.994	0.006
S42.41 Fracture of lower end of humerus (open)	0.000	0.994	0.006
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.000	0.994	0.006
E22.9 Hyperfunction of pituitary gland, unspecified	0.006	0.994	0.000
E22.8 Other hyperfunction of pituitary gland	0.005	0.994	0.000
F99 Mental disorder, not otherwise specified	0.000	0.994	0.006
E61.9 Deficiency of nutrient element, unspecified	0.005	0.994	0.000
E61.8 Deficiency of other specified nutrient elements	0.005	0.994	0.000
E61.7 Deficiency of multiple nutrient elements	0.005	0.994	0.000
E61.6 Vanadium deficiency	0.005	0.994	0.000
E61.5 Molybdenum deficiency	0.005	0.994	0.000
E61.4 Chromium deficiency	0.005	0.994	0.000
E61.3 Manganese deficiency	0.005	0.994	0.000
E61.0 Copper deficiency	0.005	0.994	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.000	0.995	0.005
Z93.1 Gastrostomy status	0.005	0.995	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.000	0.995	0.005
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.000	0.995	0.005
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.005	0.995	0.000
Y83.4 Other reconstructive surgery	0.000	0.995	0.005
S42.31 Fracture of shaft of humerus (open)	0.000	0.995	0.005
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.000	0.995	0.005
I63.9 Cerebral infarction, unspecified	0.005	0.995	0.000
S42.11 Fracture of scapula (open)	0.000	0.995	0.005
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.000	0.995	0.005
N83.0 Follicular cyst of ovary	0.005	0.995	0.000
E21.3 Hyperparathyroidism, unspecified	0.005	0.995	0.000
I63.8 Other cerebral infarction	0.005	0.995	0.000
K65 Peritonitis	0.005	0.995	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.000	0.995	0.005
S42.10 Fracture of scapula (closed)	0.000	0.995	0.005
S42.0 Fracture of clavicle	0.000	0.995	0.005
E61.2 Magnesium deficiency	0.004	0.995	0.001
F25 Schizoaffective disorders	0.000	0.995	0.005
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.005	0.995	0.000
I63 Cerebral infarction	0.005	0.995	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.995	0.005
M54.22 Cervicalgia (Cervical region)	0.000	0.995	0.005
S42.2 Fracture of upper end of humerus	0.000	0.996	0.004
F25.2 Schizoaffective disorder, mixed type	0.000	0.996	0.004
Y40.0 Penicillins	0.004	0.996	0.000
Y40.3 Macrolides	0.004	0.996	0.000
F25.9 Schizoaffective disorder, unspecified	0.000	0.996	0.004
S42.30 Fracture of shaft of humerus (closed)	0.000	0.996	0.004
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.000	0.996	0.004
Y40.7 Antifungal antibiotics, systemically used	0.004	0.996	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.004	0.996	0.000
K65.9 Peritonitis, unspecified	0.004	0.996	0.000
Y40 Systemic antibiotics	0.004	0.996	0.000
Q61.0 Congenital single renal cyst	0.000	0.996	0.004
Z93.3 Colostomy status	0.004	0.996	0.000
E00-E07 Disorders of thyroid gland	0.004	0.996	0.000
M65.34 Trigger finger-Hand	0.004	0.996	0.000
F22 Persistent delusional disorders	0.000	0.996	0.004
F84.5 Asperger's syndrome	0.000	0.996	0.004
E22.0 Acromegaly and pituitary gigantism	0.003	0.996	0.000
F20.0 Paranoid schizophrenia	0.000	0.996	0.004
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.996	0.004
D72.8 Other specified disorders of white blood cells	0.000	0.996	0.004
F25.1 Schizoaffective disorder, depressive type	0.000	0.996	0.004
S02.10 Fracture of base of skull (closed)	0.004	0.996	0.000
F20 Schizophrenia	0.000	0.996	0.004
F25.8 Other schizoaffective disorders	0.000	0.996	0.003
E22.1 Hyperprolactinaemia	0.003	0.996	0.001
M79.28 Neuralgia and neuritis, unspecified (Other)	0.000	0.996	0.004
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.003	0.996	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.003	0.996	0.000
F28 Other nonorganic psychotic disorders	0.000	0.996	0.003
F24 Induced delusional disorder	0.000	0.996	0.003
F21 Schizotypal disorder	0.000	0.996	0.003
K65.0 Acute peritonitis	0.003	0.996	0.000
S42.01 Fracture of clavicle (open)	0.000	0.997	0.003
F25.0 Schizoaffective disorder, manic type	0.000	0.997	0.003
Y40.1 Cefalosporins and other -lactam antibiotics	0.003	0.997	0.000
S42.21 Fracture of upper end of humerus (open)	0.000	0.997	0.003
N85.0 Endometrial glandular hyperplasia	0.003	0.997	0.000
R40.2 Coma, unspecified	0.000	0.997	0.003
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.003	0.997	0.000
M79.2 Neuralgia and neuritis, unspecified	0.000	0.997	0.003
F22.9 Persistent delusional disorder, unspecified	0.000	0.997	0.003
S19.9 Unspecified injury of neck	0.003	0.997	0.000
Y40.8 Other systemic antibiotics	0.003	0.997	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.997	0.003
O67.9 Intrapartum haemorrhage, unspecified	0.000	0.997	0.003
F20.5 Residual schizophrenia	0.000	0.997	0.003
I36 Nonrheumatic tricuspid valve disorders	0.003	0.997	0.000
Y40.2 Chloramphenicol group	0.003	0.997	0.000
S19.8 Other specified injuries of neck	0.003	0.997	0.000
E06 Thyroiditis	0.003	0.997	0.000
Z93 Artificial opening status	0.003	0.997	0.000
F99-F99 Unspecified mental disorder	0.000	0.997	0.003
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.003	0.997	0.000
W06.0 Home	0.000	0.997	0.003
T82.0 Mechanical complication of heart valve prosthesis	0.003	0.997	0.000
Z57.2 Occupational exposure to dust	0.003	0.997	0.000
S19 Other and unspecified injuries of neck	0.003	0.997	0.000
Y40.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
Z88.2 Personal history of allergy to sulphonamides	0.003	0.997	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.003	0.997	0.000
R60 Oedema, not elsewhere classified	0.003	0.997	0.000
E06.3 Autoimmune thyroiditis	0.003	0.997	0.000
Y40.4 Tetracyclines	0.003	0.997	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.003	0.997	0.000
E00 Congenital iodine-deficiency syndrome	0.003	0.997	0.000
F22.8 Other persistent delusional disorders	0.000	0.997	0.003
H69.9 Eustachian tube disorder, unspecified	0.003	0.997	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.003	0.997	0.000
F23 Acute and transient psychotic disorders	0.000	0.997	0.003
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.000	0.997	0.003
F20.6 Simple schizophrenia	0.000	0.997	0.003
F20.4 Postschizophrenic depression	0.000	0.997	0.003
F20.3 Undifferentiated schizophrenia	0.000	0.997	0.003
F20.1 Hebephrenic schizophrenia	0.000	0.997	0.003
Y40.6 Rifamycins	0.003	0.997	0.000
Z93.0 Tracheostomy status	0.003	0.997	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.003	0.997	0.000
F31 Bipolar affective disorder	0.000	0.997	0.003
M54.49 Lumbago with sciatica (Site unspecified)	0.000	0.997	0.003
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.000	0.997	0.003
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.000	0.997	0.003
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.000	0.997	0.003
Q87.4 Marfan's syndrome	0.000	0.997	0.003
Y40.5 Aminoglycosides	0.003	0.997	0.000
F22.0 Delusional disorder	0.000	0.997	0.003
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
E04 Other non-toxic goitre	0.003	0.997	0.000
E04.9 Non-toxic goitre, unspecified	0.003	0.997	0.000
K38.9 Disease of appendix, unspecified	0.000	0.997	0.003
Z93.8 Other artificial opening status	0.003	0.997	0.000
E04.0 Non-toxic diffuse goitre	0.003	0.997	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.003	0.997	0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.000	0.997	0.003
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.000	0.997	0.003
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.000	0.997	0.003
F20.8 Other schizophrenia	0.000	0.997	0.002
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.003	0.997	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.997	0.003
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.003	0.997	0.000
F20.2 Catatonic schizophrenia	0.000	0.997	0.002
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.002	0.997	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.002	0.997	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.002	0.997	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.002	0.997	0.000
K38.1 Appendicular concretions	0.000	0.997	0.002
S12.1 Fracture of second cervical vertebra	0.002	0.997	0.000
Z93.4 Other artificial openings of gastro-intestinal tract status	0.002	0.997	0.000
E06.4 Drug-induced thyroiditis	0.002	0.997	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.002	0.997	0.000
E06.1 Subacute thyroiditis	0.002	0.997	0.000
E06.0 Acute thyroiditis	0.002	0.997	0.000
Q60.0 Renal agenesis, unilateral	0.000	0.997	0.002
E21.0 Primary hyperparathyroidism	0.002	0.998	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.998	0.002
E02 Subclinical iodine-deficiency hypothyroidism	0.002	0.998	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.998	0.002
S19.7 Multiple injuries of neck	0.002	0.998	0.000
K38 Other diseases of appendix	0.000	0.998	0.002
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
S51.8 Open wound of other parts of forearm	0.000	0.998	0.002
H36.0 Diabetic retinopathy	0.002	0.998	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.002	0.998	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.002	0.998	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.002	0.998	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.002	0.998	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.002	0.998	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.002	0.998	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.002	0.998	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.000	0.998	0.002
E06.5 Other chronic thyroiditis	0.002	0.998	0.000
Z93.5 Cystostomy status	0.002	0.998	0.000
S82.21 Fracture of shaft of tibia (open)	0.002	0.998	0.000
F23.8 Other acute and transient psychotic disorders	0.000	0.998	0.002
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.998	0.002
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.998	0.002
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.998	0.002
V18.0 Driver injured in nontraffic accident	0.000	0.998	0.002
S12 Fracture of neck	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.002	0.998	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations