TreeWAS – Variant ID: rs4692031

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.996	0.004
J30-J39 Other diseases of upper respiratory tract	0.996	0.004
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.990	0.010
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.985	0.015
Chapter IV Endocrine, nutritional and metabolic diseases	0.985	0.015
J33 Nasal polyp	0.984	0.016
R42 Dizziness and giddiness	0.983	0.017
D60-D64 Aplastic and other anaemias	0.982	0.018
E70-E90 Metabolic disorders	0.977	0.023
D64 Other anaemias	0.975	0.025
Chapter I Certain infectious and parasitic diseases	0.973	0.027
Chapter VI Diseases of the nervous system	0.969	0.031
S60-S69 Injuries to the wrist and hand	0.969	0.031
D64.9 Anaemia, unspecified	0.968	0.032
J40-J47 Chronic lower respiratory diseases	0.966	0.034
S80-S89 Injuries to the knee and lower leg	0.965	0.035
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.963	0.037
Chapter V Mental and behavioural disorders	0.955	0.045
Chapter VIII Diseases of the ear and mastoid process	0.949	0.051
J90-J94 Other diseases of pleura	0.948	0.052
E87 Other disorders of fluid, electrolyte and acid-base balance	0.947	0.053
J09-J18 Influenza and pneumonia	0.946	0.054
S90-S99 Injuries to the ankle and foot	0.943	0.057
S61 Open wound of wrist and hand	0.931	0.069
A30-A49 Other bacterial diseases	0.928	0.072
J95-J99 Other diseases of the respiratory system	0.927	0.073
J80-J84 Other respiratory diseases principally affecting the interstitium	0.925	0.075
J00-J06 Acute upper respiratory infections	0.924	0.076
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.922	0.078
E87.2 Acidosis	0.910	0.090
J33.0 Polyp of nasal cavity	0.906	0.094
J45 Asthma	0.906	0.094
Chapter XV Pregnancy, childbirth and the puerperium	0.905	0.095
J33.9 Nasal polyp, unspecified	0.902	0.098
J60-J70 Lung diseases due to external agents	0.902	0.098
S80 Superficial injury of lower leg	0.901	0.099
J18 Pneumonia, organism unspecified	0.899	0.101
T36-T50 Poisoning by drugs, medicaments and biological substances	0.895	0.105
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.893	0.107
S40-S49 Injuries to the shoulder and upper arm	0.891	0.109
R20 Disturbances of skin sensation	0.891	0.109
Chapter XX External causes of morbidity and mortality	0.885	0.115
J30 Vasomotor and allergic rhinitis	0.883	0.117
R44 Other symptoms and signs involving general sensations and perceptions	0.882	0.118
J90 Pleural effusion, not elsewhere classified	0.880	0.120
F00-F09 Organic, including symptomatic, mental disorders	0.876	0.124
J43 Emphysema	0.875	0.125
J33.8 Other polyp of sinus	0.875	0.125
J18.1 Lobar pneumonia, unspecified	0.875	0.125
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.873	0.127
J98 Other respiratory disorders	0.873	0.127
A00-A09 Intestinal infectious diseases	0.873	0.127
R19 Other symptoms and signs involving the digestive system and abdomen	0.873	0.127
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.872	0.128
G90-G99 Other disorders of the nervous system	0.872	0.128
E50-E64 Other nutritional deficiencies	0.870	0.130
H90-H95 Other disorders of ear	0.859	0.141
S61.1 Open wound of finger(s) with damage to nail	0.853	0.147
O60-O75 Complications of labour and delivery	0.853	0.147
J02 Acute pharyngitis	0.848	0.152
R40 Somnolence, stupor and coma	0.848	0.152
F30-F39 Mood [affective] disorders	0.846	0.154
J98.1 Pulmonary collapse	0.841	0.159
A49 Bacterial infection of unspecified site	0.841	0.159
S00-S09 Injuries to the head	0.836	0.164
S70-S79 Injuries to the hip and thigh	0.833	0.167
G30-G32 Other degenerative diseases of the nervous system	0.832	0.168
R21 Rash and other nonspecific skin eruption	0.832	0.168
T66-T78 Other and unspecified effects of external causes	0.831	0.169
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.831	0.169
R18 Ascites	0.830	0.170
D70-D77 Other diseases of blood and blood-forming organs	0.827	0.173
S92 Fracture of foot, except ankle	0.826	0.174
E87.5 Hyperkalaemia	0.820	0.180
E83 Disorders of mineral metabolism	0.817	0.183
R20.2 Paraesthesia of skin	0.815	0.185
R93 Abnormal findings on diagnostic imaging of other body structures	0.813	0.187
J84 Other interstitial pulmonary diseases	0.812	0.188
J91 Pleural effusion in conditions classified elsewhere	0.812	0.188
J45.0 Predominantly allergic asthma	0.812	0.188
R91 Abnormal findings on diagnostic imaging of lung	0.811	0.189
J43.9 Emphysema, unspecified	0.810	0.190
S61.0 Open wound of finger(s) without damage to nail	0.810	0.190
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.809	0.191
J40 Bronchitis, not specified as acute or chronic	0.809	0.191
D64.8 Other specified anaemias	0.809	0.191
S80.9 Superficial injury of lower leg, unspecified	0.808	0.192
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.808	0.192
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.806	0.194
Chapter XXII Codes for special purposes	0.802	0.198
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.801	0.199
E86 Volume depletion	0.800	0.200
O94-O99 Other obstetric conditions, not elsewhere classified	0.799	0.201
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.799	0.201
J32 Chronic sinusitis	0.798	0.202
S66 Injury of muscle and tendon at wrist and hand level	0.797	0.203
R19.5 Other fecal abnormalities	0.797	0.203
J02.9 Acute pharyngitis, unspecified	0.793	0.207
J35 Chronic diseases of tonsils and adenoids	0.791	0.209
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.789	0.211
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.789	0.211
J45.9 Asthma, unspecified	0.788	0.212
R16.0 Hepatomegaly, not elsewhere classified	0.788	0.212
A08 Viral and other specified intestinal infections	0.787	0.213
S91 Open wound of ankle and foot	0.787	0.213
H60-H62 Diseases of external ear	0.786	0.214
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.786	0.214
Chapter XIV Diseases of the genitourinary system	0.785	0.215
S81 Open wound of lower leg	0.785	0.215
S99 Other and unspecified injuries of ankle and foot	0.784	0.215
A80-A89 Viral infections of the central nervous system	0.784	0.216
R12 Heartburn	0.783	0.217
G70-G73 Diseases of myoneural junction and muscle	0.783	0.217
H93 Other disorders of ear, not elsewhere classified	0.781	0.219
T39.1 4-Aminophenol derivatives	0.781	0.219
R17 Unspecified jaundice	0.781	0.219
E88 Other metabolic disorders	0.780	0.220
J69 Pneumonitis due to solids and liquids	0.780	0.220
E73 Lactose intolerance	0.779	0.221
S42 Fracture of shoulder and upper arm	0.778	0.222
J30.1 Allergic rhinitis due to pollen	0.774	0.226
R15 Faecal incontinence	0.773	0.227
J00 Acute nasopharyngitis [common cold]	0.773	0.227
F99-F99 Unspecified mental disorder	0.773	0.227
E53 Deficiency of other B group vitamins	0.771	0.229
R41 Other symptoms and signs involving cognitive functions and awareness	0.770	0.230
D80-D89 Certain disorders involving the immune mechanism	0.770	0.230
G50-G59 Nerve, nerve root and plexus disorders	0.767	0.233
J34 Other disorders of nose and nasal sinuses	0.766	0.234
G93 Other disorders of brain	0.765	0.235
O70 Perineal laceration during delivery	0.764	0.236
R44.3 Hallucinations, unspecified	0.763	0.237
F31 Bipolar affective disorder	0.761	0.239
H65-H75 Diseases of middle ear and mastoid	0.760	0.240
X60-X84 Intentional self-harm	0.760	0.240
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.756	0.244
N17-N19 Renal failure	0.755	0.245
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.753	0.247
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.751	0.249
J81 Pulmonary oedema	0.751	0.249
Chapter II Neoplasms	0.750	0.250
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.749	0.251
A46 Erysipelas	0.749	0.251
S10-S19 Injuries to the neck	0.749	0.251
T15-T19 Effects of foreign body entering through natural orifice	0.748	0.252
B15-B19 Viral hepatitis	0.747	0.253
A49.0 Staphylococcal infection, unspecified	0.746	0.254
A40 Streptococcal septicaemia	0.745	0.255
Chapter XI Diseases of the digestive system	0.744	0.256
R23 Other skin changes	0.744	0.256
D63 Anaemia in chronic diseases classified elsewhere	0.743	0.257
R14 Flatulence and related conditions	0.739	0.261
J80 Adult respiratory distress syndrome	0.739	0.261
R11 Nausea and vomiting	0.739	0.261
S61.7 Multiple open wounds of wrist and hand	0.737	0.263
S61.8 Open wound of other parts of wrist and hand	0.737	0.263
F03 Unspecified dementia	0.734	0.266
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.734	0.266
N99-N99 Other disorders of the genitourinary system	0.732	0.268
G40-G47 Episodic and paroxysmal disorders	0.731	0.269
R40.0 Somnolence	0.731	0.269
R29.6 Tendency to fall, not elsewhere classified	0.731	0.269
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.730	0.270
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.730	0.270
G30 Alzheimer's disease	0.729	0.271
J93 Pneumothorax	0.727	0.273
H93.1 Tinnitus	0.725	0.274
A08.4 Viral intestinal infection, unspecified	0.725	0.275
J84.1 Other interstitial pulmonary diseases with fibrosis	0.724	0.276
E80 Disorders of porphyrin and bilirubin metabolism	0.724	0.276
W00-W19 Falls	0.724	0.276
R47-R49 Symptoms and signs involving speech and voice	0.724	0.276
J15 Bacterial pneumonia, not elsewhere classified	0.723	0.276
S92.0 Fracture of calcaneus	0.723	0.277
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.723	0.277
A41 Other septicaemia	0.723	0.277
E87.7 Fluid overload	0.721	0.279
K70-K77 Diseases of liver	0.720	0.280
R20.8 Other and unspecified disturbances of skin sensation	0.720	0.280
S62 Fracture at wrist and hand level	0.719	0.281
S20-S29 Injuries to the thorax	0.718	0.282
F33 Recurrent depressive disorder	0.718	0.282
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
C15-C26 Malignant neoplasms of digestive organs	0.716	0.284
R73 Elevated blood glucose level	0.716	0.284
S01 Open wound of head	0.715	0.285
R46 Symptoms and signs involving appearance and behaviour	0.714	0.286
R43 Disturbances of smell and taste	0.714	0.286
J37 Chronic laryngitis and laryngotracheitis	0.714	0.286
H90 Conductive and sensorineural hearing loss	0.713	0.287
T79-T79 Certain early complications of trauma	0.713	0.287
R44.0 Auditory hallucinations	0.711	0.289
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.711	0.289
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.710	0.290
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.710	0.290
F00 Dementia in Alzheimer's disease	0.710	0.290
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.710	0.290
D55-D59 Haemolytic anaemias	0.710	0.290
R26 Abnormalities of gait and mobility	0.710	0.290
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.709	0.290
S42.2 Fracture of upper end of humerus	0.708	0.292
S89 Other and unspecified injuries of lower leg	0.708	0.292
S80.8 Other superficial injuries of lower leg	0.707	0.292
O62 Abnormalities of forces of labour	0.707	0.293
S60 Superficial injury of wrist and hand	0.707	0.293
D70 Agranulocytosis	0.706	0.293
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.706	0.294
E40-E46 Malnutrition	0.706	0.294
J33.1 Polypoid sinus degeneration	0.705	0.295
G35-G37 Demyelinating diseases of the central nervous system	0.704	0.296
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.704	0.296
E87.0 Hyperosmolality and hypernatraemia	0.702	0.298
E53.8 Deficiency of other specified B group vitamins	0.701	0.299
D61 Other aplastic anaemias	0.700	0.299
E85 Amyloidosis	0.700	0.300
E84 Cystic fibrosis	0.700	0.300
E79 Disorders of purine and pyrimidine metabolism	0.700	0.300
E77 Disorders of glycoprotein metabolism	0.700	0.300
E76 Disorders of glycosaminoglycan metabolism	0.700	0.300
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.700	0.300
E74 Other disorders of carbohydrate metabolism	0.700	0.300
E72 Other disorders of amino-acid metabolism	0.700	0.300
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.700	0.300
E70 Disorders of aromatic amino-acid metabolism	0.700	0.300
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.700	0.300
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.699	0.301
D64.4 Congenital dyserythropoietic anaemia	0.699	0.301
D64.3 Other sideroblastic anaemias	0.699	0.301
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.699	0.301
D64.1 Secondary sideroblastic anaemia due to disease	0.699	0.301
D64.0 Hereditary sideroblastic anaemia	0.699	0.301
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.699	0.301
S80.1 Contusion of other and unspecified parts of lower leg	0.699	0.301
B99-B99 Other infectious diseases	0.698	0.302
B90-B94 Sequelae of infectious and parasitic diseases	0.698	0.302
B85-B89 Pediculosis, acariasis and other infestations	0.698	0.302
B65-B83 Helminthiases	0.698	0.302
B50-B64 Protozoal diseases	0.698	0.302
B20-B24 Human immunodeficiency virus [HIV] disease	0.698	0.302
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.698	0.302
A75-A79 Rickettsioses	0.698	0.302
A70-A74 Other diseases caused by chlamydiae	0.698	0.302
A65-A69 Other spirochaetal diseases	0.698	0.302
A50-A64 Infections with a predominantly sexual mode of transmission	0.698	0.302
A20-A28 Certain zoonotic bacterial diseases	0.698	0.302
A15-A19 Tuberculosis	0.698	0.302
F80-F89 Disorders of psychological development	0.698	0.302
S64 Injury of nerves at wrist and hand level	0.697	0.302
S46 Injury of muscle and tendon at shoulder and upper arm level	0.696	0.304
G00-G09 Inflammatory diseases of the central nervous system	0.695	0.305
S69 Other and unspecified injuries of wrist and hand	0.694	0.305
S67 Crushing injury of wrist and hand	0.694	0.305
S65 Injury of blood vessels at wrist and hand level	0.694	0.305
S72 Fracture of femur	0.694	0.306
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.694	0.306
B35-B49 Mycoses	0.694	0.306
J35.0 Chronic tonsillitis	0.694	0.306
S80.0 Contusion of knee	0.694	0.306
J41 Simple and mucopurulent chronic bronchitis	0.693	0.307
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.693	0.307
R45 Symptoms and signs involving emotional state	0.692	0.308
D62 Acute posthaemorrhagic anaemia	0.692	0.308
J69.0 Pneumonitis due to food and vomit	0.692	0.308
S88 Traumatic amputation of lower leg	0.692	0.308
S87 Crushing injury of lower leg	0.692	0.308
S86 Injury of muscle and tendon at lower leg level	0.692	0.308
S85 Injury of blood vessels at lower leg level	0.692	0.308
S84 Injury of nerves at lower leg level	0.692	0.308
R79 Other abnormal findings of blood chemistry	0.691	0.309
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.691	0.309
T68 Hypothermia	0.690	0.310
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.690	0.310
H80-H83 Diseases of inner ear	0.689	0.311
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.689	0.311
G80-G83 Cerebral palsy and other paralytic syndromes	0.688	0.312
E55 Vitamin D deficiency	0.688	0.312
J94 Other pleural conditions	0.687	0.313
A49.8 Other bacterial infections of unspecified site	0.686	0.314
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.685	0.315
F70-F79 Mental retardation	0.685	0.315
F60-F69 Disorders of adult personality and behaviour	0.685	0.315
R00 Abnormalities of heart beat	0.684	0.316
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.683	0.317
J39 Other diseases of upper respiratory tract	0.683	0.317
J13 Pneumonia due to Streptococcus pneumoniae	0.681	0.319
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.679	0.321
N19 Unspecified renal failure	0.679	0.321
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.679	0.321
E87.4 Mixed disorder of acid-base balance	0.679	0.321
E87.3 Alkalosis	0.679	0.321
E20-E35 Disorders of other endocrine glands	0.679	0.321
J17 Pneumonia in diseases classified elsewhere	0.678	0.322
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.678	0.322
J12 Viral pneumonia, not elsewhere classified	0.678	0.322
J11 Influenza, virus not identified	0.678	0.322
J10 Influenza due to identified influenza virus	0.678	0.322
J14 Pneumonia due to Haemophilus influenzae	0.678	0.322
J09 Influenza due to certain identified influenza virus	0.678	0.322
E83.5 Disorders of calcium metabolism	0.677	0.323
N17 Acute renal failure	0.677	0.323
S98 Traumatic amputation of ankle and foot	0.676	0.324
S97 Crushing injury of ankle and foot	0.676	0.324
S96 Injury of muscle and tendon at ankle and foot level	0.676	0.324
S95 Injury of blood vessels at ankle and foot level	0.676	0.324
S94 Injury of nerves at ankle and foot level	0.676	0.324
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.676	0.324
S90 Superficial injury of ankle and foot	0.676	0.324
G90 Disorders of autonomic nervous system	0.676	0.324
S49 Other and unspecified injuries of shoulder and upper arm	0.675	0.325
S91.1 Open wound of toe(s) without damage to nail	0.674	0.325
G93.8 Other specified disorders of brain	0.674	0.326
S82 Fracture of lower leg, including ankle	0.673	0.326
O70.1 Second degree perineal laceration during delivery	0.674	0.326
J46 Status asthmaticus	0.672	0.328
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.672	0.328
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.671	0.329
J95 Postprocedural respiratory disorders, not elsewhere classified	0.671	0.329
S99.9 Unspecified injury of ankle and foot	0.671	0.329
J31.0 Chronic rhinitis	0.670	0.330
J30.4 Allergic rhinitis, unspecified	0.670	0.330
E10-E14 Diabetes mellitus	0.669	0.331
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.668	0.331
Y52 Agents primarily affecting the cardiovascular system	0.667	0.333
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.667	0.333
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.666	0.333
G45 Transient cerebral ischaemic attacks and related syndromes	0.666	0.334
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.666	0.334
R72 Abnormality of white blood cells, not elsewhere classified	0.666	0.334
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.665	0.334
A48 Other bacterial diseases, not elsewhere classified	0.665	0.335
A44 Bartonellosis	0.665	0.335
A43 Nocardiosis	0.665	0.335
A42 Actinomycosis	0.665	0.335
A39 Meningococcal infection	0.665	0.335
A37 Whooping cough	0.665	0.335
A36 Diphtheria	0.665	0.335
A32 Listeriosis	0.665	0.335
A31 Infection due to other mycobacteria	0.665	0.335
A30 Leprosy [Hansen's disease]	0.665	0.335
A38 Scarlet fever	0.665	0.335
A35 Other tetanus	0.665	0.335
A34 Obstetrical tetanus	0.665	0.335
A33 Tetanus neonatorum	0.665	0.335
K70 Alcoholic liver disease	0.665	0.335
X40-X49 Accidental poisoning by and exposure to noxious substances	0.665	0.335
J30.3 Other allergic rhinitis	0.665	0.335
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.665	0.335
J99 Respiratory disorders in diseases classified elsewhere	0.665	0.335
J96 Respiratory failure, not elsewhere classified	0.665	0.335
R10 Abdominal and pelvic pain	0.664	0.336
J82 Pulmonary eosinophilia, not elsewhere classified	0.663	0.337
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.663	0.337
J04 Acute laryngitis and tracheitis	0.663	0.337
J01 Acute sinusitis	0.663	0.337
R92 Abnormal findings on diagnostic imaging of breast	0.661	0.339
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.660	0.340
S42.20 Fracture of upper end of humerus (closed)	0.657	0.343
F05 Delirium, not induced by alcohol and other psychoactive substances	0.657	0.343
S30 Superficial injury of abdomen, lower back and pelvis	0.657	0.343
S81.9 Open wound of lower leg, part unspecified	0.656	0.343
N25-N29 Other disorders of kidney and ureter	0.656	0.344
O75 Other complications of labour and delivery, not elsewhere classified	0.656	0.344
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.656	0.344
G30.9 Alzheimer's disease, unspecified	0.655	0.345
G12 Spinal muscular atrophy and related syndromes	0.654	0.346
K76 Other diseases of liver	0.653	0.347
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.653	0.347
R00.0 Tachycardia, unspecified	0.650	0.350
J45.8 Mixed asthma	0.650	0.350
J45.1 Nonallergic asthma	0.650	0.350
S92.00 Fracture of calcaneus (closed)	0.649	0.351
O85-O92 Complications predominantly related to the puerperium	0.649	0.351
A87 Viral meningitis	0.648	0.352
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.648	0.352
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.647	0.352
J70 Respiratory conditions due to other external agents	0.647	0.353
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.647	0.353
J67 Hypersensitivity pneumonitis due to organic dust	0.647	0.353
J66 Airway disease due to specific organic dust	0.647	0.353
J63 Pneumoconiosis due to other inorganic dusts	0.647	0.353
J62 Pneumoconiosis due to dust containing silica	0.647	0.353
J65 Pneumoconiosis associated with tuberculosis	0.647	0.353
J64 Unspecified pneumoconiosis	0.647	0.353
J60 Coalworker's pneumoconiosis	0.647	0.353
S80.7 Multiple superficial injuries of lower leg	0.646	0.354
R25 Abnormal involuntary movements	0.646	0.354
S68 Traumatic amputation of wrist and hand	0.646	0.354
R13 Dysphagia	0.645	0.355
J18.8 Other pneumonia, organism unspecified	0.645	0.355
J18.2 Hypostatic pneumonia, unspecified	0.645	0.355
K40-K46 Hernia	0.645	0.355
K50-K52 Noninfective enteritis and colitis	0.644	0.356
Y46 Antiepileptics and anti-Parkinsonism drugs	0.644	0.356
J03 Acute tonsillitis	0.644	0.356
F99 Mental disorder, not otherwise specified	0.643	0.357
O68 Labour and delivery complicated by foetal stress [distress]	0.643	0.357
G95 Other diseases of spinal cord	0.642	0.358
R09.0 Asphyxia	0.642	0.358
F40-F48 Neurotic, stress-related and somatoform disorders	0.642	0.358
S66.8 Injury of other muscles and tendons at wrist and hand level	0.642	0.358
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.642	0.358
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.642	0.358
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.642	0.358
T46 Poisoning by agents primarily affecting the cardiovascular system	0.642	0.358
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.642	0.358
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.642	0.358
T41 Poisoning by anaesthetics and therapeutic gases	0.642	0.358
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.642	0.358
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.642	0.358
T36 Poisoning by systemic antibiotics	0.642	0.358
R76 Other abnormal immunological findings in serum	0.642	0.358
R16.1 Splenomegaly, not elsewhere classified	0.641	0.358
H60 Otitis externa	0.641	0.358
J42 Unspecified chronic bronchitis	0.641	0.359
H66 Suppurative and unspecified otitis media	0.641	0.359
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.640	0.360
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.640	0.360
S48 Traumatic amputation of shoulder and upper arm	0.639	0.361
S45 Injury of blood vessels at shoulder and upper arm level	0.639	0.361
S44 Injury of nerves at shoulder and upper arm level	0.639	0.361
S41 Open wound of shoulder and upper arm	0.639	0.361
S40 Superficial injury of shoulder and upper arm	0.639	0.361
S47 Crushing injury of shoulder and upper arm	0.639	0.361
R20.3 Hyperaesthesia	0.639	0.361
R20.1 Hypoaesthesia of skin	0.639	0.361
R20.0 Anaesthesia of skin	0.639	0.361
R19.4 Change in bowel habit	0.639	0.361
N99.4 Postprocedural pelvic peritoneal adhesions	0.639	0.361
E83.4 Disorders of magnesium metabolism	0.638	0.362
G96 Other disorders of central nervous system	0.638	0.362
F31.9 Bipolar affective disorder, unspecified	0.637	0.363
S92.3 Fracture of metatarsal bone	0.637	0.363
R94 Abnormal results of function studies	0.637	0.363
S01.5 Open wound of lip and oral cavity	0.637	0.363
E73.9 Lactose intolerance, unspecified	0.637	0.363
R06 Abnormalities of breathing	0.637	0.363
O72 Postpartum haemorrhage	0.636	0.364
D86 Sarcoidosis	0.635	0.365
Y35-Y36 Legal intervention and operations of war	0.634	0.365
Y10-Y34 Event of undetermined intent	0.634	0.365
Y00-Y09 Assault	0.634	0.365
X85-X99 Assault	0.634	0.365
X58-X59 Accidental exposure to other and unspecified factors	0.634	0.365
X50-X57 Overexertion, travel and privation	0.634	0.365
X30-X39 Exposure to forces of nature	0.634	0.365
X20-X29 Contact with venomous animals and plants	0.634	0.365
X10-X19 Contact with heat and hot substances	0.634	0.365
X00-X09 Exposure to smoke, fire and flames	0.634	0.365
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.634	0.365
W75-W84 Other accidental threats to breathing	0.634	0.365
W65-W74 Accidental drowning and submersion	0.634	0.365
W50-W64 Exposure to animate mechanical forces	0.634	0.365
V98-V99 Other and unspecified transport accidents	0.634	0.365
V95-V97 Air and space transport accidents	0.634	0.365
V90-V94 Water transport accidents	0.634	0.365
V80-V89 Other land transport accidents	0.634	0.365
V70-V79 Bus occupant injured in transport accident	0.634	0.365
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.634	0.365
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.634	0.365
V40-V49 Car occupant injured in transport accident	0.634	0.365
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.634	0.365
V20-V29 Motorcycle rider injured in transport accident	0.634	0.365
V01-V09 Pedestrian injured in transport accident	0.634	0.365
R90 Abnormal findings on diagnostic imaging of central nervous system	0.634	0.366
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.634	0.366
J30.2 Other seasonal allergic rhinitis	0.633	0.367
J30.0 Vasomotor rhinitis	0.633	0.367
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.632	0.367
R44.2 Other hallucinations	0.632	0.367
R44.1 Visual hallucinations	0.632	0.368
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.632	0.368
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.630	0.370
F31.6 Bipolar affective disorder, current episode mixed	0.630	0.370
T78 Adverse effects, not elsewhere classified	0.630	0.370
J47 Bronchiectasis	0.629	0.371
R40.2 Coma, unspecified	0.629	0.371
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.629	0.371
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.628	0.372
F02 Dementia in other diseases classified elsewhere	0.628	0.372
F01 Vascular dementia	0.628	0.372
F09 Unspecified organic or symptomatic mental disorder	0.628	0.372
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.628	0.372
R27 Other lack of coordination	0.628	0.372
G50 Disorders of trigeminal nerve	0.628	0.372
J43.8 Other emphysema	0.628	0.372
J43.2 Centrilobular emphysema	0.628	0.372
J43.1 Panlobular emphysema	0.628	0.372
J43.0 MacLeod's syndrome	0.628	0.372
C15 Malignant neoplasm of oesophagus	0.627	0.373
O70.0 First degree perineal laceration during delivery	0.627	0.373

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations