TreeWAS – Variant ID: rs4728142

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K50.9 Crohn's disease, unspecified	0.613	0.387	0.000
K50 Crohn's disease [regional enteritis]	0.612	0.388	0.000
K50.0 Crohn's disease of small intestine	0.603	0.397	0.000
K50.1 Crohn's disease of large intestine	0.574	0.426	0.000
K50-K52 Noninfective enteritis and colitis	0.494	0.506	0.000
K51 Ulcerative colitis	0.484	0.516	0.000
K51.9 Ulcerative colitis, unspecified	0.478	0.522	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.413	0.587	0.000
K51.4 Pseudopolyposis of colon	0.404	0.596	0.000
K51.8 Other ulcerative colitis	0.374	0.626	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.345	0.655	0.000
K51.5 Mucosal proctocolitis	0.285	0.715	0.000
K51.2 Ulcerative (chronic) proctitis	0.275	0.725	0.000
K50.8 Other Crohn's disease	0.258	0.742	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.256	0.744	0.000
K74 Fibrosis and cirrhosis of liver	0.203	0.797	0.000
K74.3 Primary biliary cirrhosis	0.203	0.797	0.000
K70-K77 Diseases of liver	0.194	0.806	0.000
K74.5 Biliary cirrhosis, unspecified	0.192	0.808	0.000
K72 Hepatic failure, not elsewhere classified	0.189	0.811	0.000
K75 Other inflammatory liver diseases	0.182	0.818	0.000
K72.0 Acute and subacute hepatic failure	0.177	0.823	0.000
K75.4 Autoimmune hepatitis	0.174	0.826	0.000
K73 Chronic hepatitis, not elsewhere classified	0.173	0.827	0.000
K52 Other non-infective gastro-enteritis and colitis	0.167	0.833	0.000
K74.1 Hepatic sclerosis	0.165	0.835	0.000
K72.1 Chronic hepatic failure	0.164	0.836	0.000
K75.9 Inflammatory liver disease, unspecified	0.162	0.838	0.000
K71 Toxic liver disease	0.158	0.842	0.000
K77 Liver disorders in diseases classified elsewhere	0.147	0.853	0.000
K74.4 Secondary biliary cirrhosis	0.146	0.854	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.146	0.854	0.000
K72.9 Hepatic failure, unspecified	0.145	0.855	0.000
K73.9 Chronic hepatitis, unspecified	0.145	0.855	0.000
K74.6 Other and unspecified cirrhosis of liver	0.144	0.856	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.142	0.858	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.139	0.861	0.000
K75.2 Nonspecific reactive hepatitis	0.131	0.869	0.000
K75.1 Phlebitis of portal vein	0.131	0.869	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.130	0.870	0.000
K75.0 Abscess of liver	0.127	0.873	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.124	0.876	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.124	0.876	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.876	0.124
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.123	0.877	0.000
K52.1 Toxic gastro-enteritis and colitis	0.120	0.880	0.000
K52.3 Indeterminate colitis	0.115	0.885	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.115	0.885	0.000
K71.9 Toxic liver disease, unspecified	0.113	0.887	0.000
K71.8 Toxic liver disease with other disorders of liver	0.113	0.887	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.113	0.887	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.113	0.887	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.113	0.887	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.113	0.887	0.000
K71.2 Toxic liver disease with acute hepatitis	0.113	0.887	0.000
K71.0 Toxic liver disease with cholestasis	0.112	0.888	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.111	0.889	0.000
K74.0 Hepatic fibrosis	0.111	0.889	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.107	0.893	0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.099	0.901	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.098	0.902	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.097	0.903	0.000
K75.8 Other specified inflammatory liver diseases	0.095	0.905	0.000
K76 Other diseases of liver	0.067	0.933	0.000
L40.9 Psoriasis, unspecified	0.060	0.940	0.000
S42.30 Fracture of shaft of humerus (closed)	0.060	0.940	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.060	0.940	0.000
K76.1 Chronic passive congestion of liver	0.052	0.948	0.000
K76.7 Hepatorenal syndrome	0.051	0.949	0.000
K76.9 Liver disease, unspecified	0.050	0.950	0.000
K76.3 Infarction of liver	0.049	0.951	0.000
K76.5 Hepatic veno-occlusive disease	0.048	0.952	0.000
K76.4 Peliosis hepatis	0.048	0.952	0.000
K76.2 Central haemorrhagic necrosis of liver	0.048	0.952	0.000
L40 Psoriasis	0.047	0.953	0.000
L40.0 Psoriasis vulgaris	0.043	0.957	0.000
Chapter XI Diseases of the digestive system	0.043	0.957	0.000
L40.4 Guttate psoriasis	0.039	0.961	0.000
L40.8 Other psoriasis	0.039	0.961	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.036	0.964	0.000
D68.2 Hereditary deficiency of other clotting factors	0.035	0.965	0.000
L40.3 Pustulosis palmaris et plantaris	0.035	0.965	0.000
L40.2 Acrodermatitis continua	0.034	0.966	0.000
D68 Other coagulation defects	0.032	0.968	0.000
L40.1 Generalised pustular psoriasis	0.031	0.969	0.000
D68.6 Other Thrombophilia	0.029	0.971	0.000
D68.9 Coagulation defect, unspecified	0.029	0.971	0.000
K76.6 Portal hypertension	0.028	0.972	0.000
D68.8 Other specified coagulation defects	0.027	0.973	0.000
D68.5 Primary Thrombophilia	0.027	0.973	0.000
S42.3 Fracture of shaft of humerus	0.027	0.973	0.000
H33.5 Other retinal detachments	0.000	0.976	0.024
K70 Alcoholic liver disease	0.023	0.977	0.000
D68.1 Hereditary factor XI deficiency	0.023	0.977	0.000
K76.8 Other specified diseases of liver	0.022	0.978	0.000
D68.4 Acquired coagulation factor deficiency	0.020	0.980	0.000
S42.31 Fracture of shaft of humerus (open)	0.018	0.981	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.017	0.983	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.017	0.983	0.000
K70.4 Alcoholic hepatic failure	0.016	0.984	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.016	0.984	0.000
K35-K38 Diseases of appendix	0.016	0.984	0.000
K90-K93 Other diseases of the digestive system	0.015	0.985	0.000
L40-L45 Papulosquamous disorders	0.014	0.986	0.000
K70.0 Alcoholic fatty liver	0.014	0.986	0.000
L40.5 Arthropathic psoriasis	0.014	0.986	0.000
K36 Other appendicitis	0.014	0.986	0.000
D66 Hereditary factor VIII deficiency	0.013	0.987	0.000
D68.0 Von Willebrand's disease	0.013	0.987	0.000
D67 Hereditary factor IX deficiency	0.012	0.987	0.000
D69 Purpura and other haemorrhagic conditions	0.012	0.988	0.000
K90 Intestinal malabsorption	0.012	0.988	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.012	0.988	0.000
K38 Other diseases of appendix	0.012	0.988	0.000
K65-K67 Diseases of peritoneum	0.011	0.989	0.000
K90.9 Intestinal malabsorption, unspecified	0.011	0.989	0.000
L44 Other papulosquamous disorders	0.011	0.989	0.000
K70.9 Alcoholic liver disease, unspecified	0.011	0.989	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.011	0.989	0.000
D69.2 Other nonthrombocytopenic purpura	0.011	0.989	0.000
L41 Parapsoriasis	0.010	0.990	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.010	0.990	0.000
L42 Pityriasis rosea	0.010	0.990	0.000
K38.9 Disease of appendix, unspecified	0.010	0.990	0.000
D69.6 Thrombocytopenia, unspecified	0.010	0.990	0.000
D69.5 Secondary thrombocytopenia	0.010	0.990	0.000
D69.1 Qualitative platelet defects	0.009	0.991	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.009	0.991	0.000
D69.8 Other specified haemorrhagic conditions	0.009	0.991	0.000
K38.2 Diverticulum of appendix	0.009	0.991	0.000
K70.1 Alcoholic hepatitis	0.009	0.991	0.000
D69.9 Haemorrhagic condition, unspecified	0.009	0.991	0.000
D69.0 Allergic purpura	0.009	0.991	0.000
K90.3 Pancreatic steatorrhoea	0.009	0.991	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.009	0.991	0.000
K90.1 Tropical sprue	0.009	0.991	0.000
K70.3 Alcoholic cirrhosis of liver	0.009	0.991	0.000
K38.3 Fistula of appendix	0.008	0.991	0.000
L44.0 Pityriasis rubra pilaris	0.008	0.991	0.000
G82.2 Paraplegia, unspecified	0.008	0.992	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.008	0.992	0.000
K38.8 Other specified diseases of appendix	0.008	0.992	0.000
K38.0 Hyperplasia of appendix	0.008	0.992	0.000
L44.9 Papulosquamous disorder, unspecified	0.008	0.992	0.000
L44.8 Other specified papulosquamous disorders	0.008	0.992	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.008	0.992	0.000
L44.3 Lichen ruber moniliformis	0.008	0.992	0.000
L44.2 Lichen striatus	0.008	0.992	0.000
L44.1 Lichen nitidus	0.008	0.992	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.008	0.992	0.000
K93.1 Megacolon in Chagas' disease	0.008	0.992	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.008	0.992	0.000
C43.9 Malignant melanoma of skin, unspecified	0.000	0.992	0.008
L41.9 Parapsoriasis, unspecified	0.008	0.992	0.000
L41.8 Other parapsoriasis	0.008	0.992	0.000
L41.5 Retiform parapsoriasis	0.008	0.992	0.000
L41.4 Large plaque parapsoriasis	0.008	0.992	0.000
L41.3 Small plaque parapsoriasis	0.008	0.992	0.000
L41.2 Lymphomatoid papulosis	0.008	0.992	0.000
L41.1 Pityriasis lichenoides chronica	0.008	0.992	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.008	0.992	0.000
K90.0 Coeliac disease	0.008	0.992	0.000
L43 Lichen planus	0.007	0.993	0.000
K90.8 Other intestinal malabsorption	0.007	0.993	0.000
G82 Paraplegia and tetraplegia	0.007	0.993	0.000
K40-K46 Hernia	0.007	0.993	0.000
G82.1 Spastic paraplegia	0.007	0.993	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.007	0.993	0.000
D61.9 Aplastic anaemia, unspecified	0.007	0.993	0.000
U80 Agent resistant to penicillin and related antibiotics	0.006	0.994	0.000
U80.1 Methicillin resistant agent	0.006	0.994	0.000
K38.1 Appendicular concretions	0.006	0.994	0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.006	0.994	0.000
K67.3 Tuberculous peritonitis	0.006	0.994	0.000
K67.2 Syphilitic peritonitis	0.006	0.994	0.000
K67.1 Gonococcal peritonitis	0.006	0.994	0.000
K67.0 Chlamydial peritonitis	0.006	0.994	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.006	0.994	0.000
D69.4 Other primary thrombocytopenia	0.006	0.994	0.000
K43 Ventral hernia	0.006	0.994	0.000
U80.0 Penicillin resistant agent	0.006	0.994	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.006	0.994	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.006	0.994	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.006	0.994	0.000
L43.8 Other lichen planus	0.006	0.994	0.000
K46 Unspecified abdominal hernia	0.006	0.994	0.000
L43.3 Subacute (active) lichen planus	0.005	0.994	0.000
L43.2 Lichenoid drug reaction	0.005	0.994	0.000
L43.1 Bullous lichen planus	0.005	0.994	0.000
L43.0 Hypertrophic lichen planus	0.005	0.994	0.000
D61 Other aplastic anaemias	0.006	0.994	0.000
G82.5 Tetraplegia, unspecified	0.005	0.995	0.000
T68 Hypothermia	0.005	0.995	0.000
G82.3 Flaccid tetraplegia	0.005	0.995	0.000
G82.0 Flaccid paraplegia	0.005	0.995	0.000
G82.4 Spastic tetraplegia	0.005	0.995	0.000
Z90.6 Acquired absence of other parts of urinary tract	0.005	0.995	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.005	0.995	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.005	0.995	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.995	0.005
U51 Admission status on psychiatric patients	0.005	0.995	0.000
K43.1 Ventral hernia with gangrene	0.005	0.995	0.000
K41 Femoral hernia	0.005	0.995	0.000
D61.0 Constitutional aplastic anaemia	0.005	0.995	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.005	0.995	0.000
K43.7 Other and unspecified ventral hernia with gangrene	0.005	0.995	0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.005	0.995	0.000
K43.5 Parastomal hernia without obstruction or gangrene	0.005	0.995	0.000
K43.4 Parastomal hernia with gangrene	0.005	0.995	0.000
K43.3 Parastomal hernia with obstruction, without gangrene	0.005	0.995	0.000
K43.2 Incisional hernia without obstruction or gangrene	0.005	0.995	0.000
K45 Other abdominal hernia	0.005	0.995	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.005	0.995	0.000
K91.3 Postoperative intestinal obstruction	0.005	0.995	0.000
K91.5 Postcholecystectomy syndrome	0.004	0.995	0.000
K91.1 Postgastric surgery syndromes	0.004	0.995	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.004	0.996	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.004	0.996	0.000
D60-D64 Aplastic and other anaemias	0.004	0.996	0.000
S42 Fracture of shoulder and upper arm	0.004	0.996	0.000
D61.1 Drug-induced aplastic anaemia	0.004	0.996	0.000
D27 Benign neoplasm of ovary	0.000	0.996	0.004
D61.8 Other specified aplastic anaemias	0.004	0.996	0.000
D61.3 Idiopathic aplastic anaemia	0.004	0.996	0.000
D61.2 Aplastic anaemia due to other external agents	0.004	0.996	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.004	0.996	0.000
K91.4 Colostomy and enterostomy malfunction	0.004	0.996	0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.004	0.996	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.004	0.996	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
H83.0 Labyrinthitis	0.000	0.996	0.004
V23.4 Driver injured in traffic accident	0.004	0.996	0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.004	0.996	0.000
U50 Level of care administered to neonates	0.004	0.996	0.000
U07 Emergency use of U07	0.004	0.996	0.000
U06 Emergency use of U06	0.004	0.996	0.000
U04 Severe acute respiratory syndrome [SARS]	0.004	0.996	0.000
U52 First in a series of a regular day/night admissions	0.004	0.996	0.000
U51.2 Previously admitted to a psychiatric hospital of another provider	0.004	0.996	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.004	0.996	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.004	0.996	0.000
S72.20 Subtrochanteric fracture (closed)	0.004	0.996	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.004
T42.4 Benzodiazepines	0.004	0.996	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.996	0.004
U51.0 Not Previously admitted to a psyciatric hospital	0.004	0.996	0.000
K65 Peritonitis	0.004	0.996	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.004	0.996	0.000
K41.1 Bilateral femoral hernia, with gangrene	0.004	0.996	0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.004	0.996	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.004	0.996	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.004	0.996	0.000
D89.1 Cryoglobulinaemia	0.004	0.996	0.000
L57.0 Actinic keratosis	0.000	0.996	0.004
S02.1 Fracture of base of skull	0.000	0.996	0.004
C43 Malignant melanoma of skin	0.000	0.996	0.004
D69.3 Idiopathic thrombocytopenic purpura	0.004	0.996	0.000
G83.9 Paralytic syndrome, unspecified	0.004	0.996	0.000
M51.8 Other specified intervertebral disk disorders	0.000	0.996	0.004
Z00.6 Examination for normal comparison and control in clinical research programme	0.004	0.996	0.000
K45.1 Other specified abdominal hernia with gangrene	0.003	0.996	0.000
S42.2 Fracture of upper end of humerus	0.004	0.996	0.000
G83 Other paralytic syndromes	0.004	0.996	0.000
B37.0 Candidal stomatitis	0.000	0.996	0.004
D89.9 Disorder involving the immune mechanism, unspecified	0.003	0.996	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.003	0.996	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.003	0.996	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.003	0.997	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.003	0.997	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.997	0.003
C43.4 Malignant melanoma of scalp and neck	0.000	0.997	0.003
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.003	0.997	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.003	0.997	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.997	0.003
U81.0 Vancomycin resistant agent	0.003	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
U81.8 Agent resistant to other vancomycin-related antibiotic	0.003	0.997	0.000
K37 Unspecified appendicitis	0.003	0.997	0.000
S02.60 Fracture of mandible (closed)	0.000	0.997	0.003
C51.9 Vulva, unspecified	0.000	0.997	0.003
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.003	0.997	0.000
D89.3 Immune reconstitution syndrome	0.003	0.997	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.003	0.997	0.000
U06.9 Emergency use of U06.9	0.003	0.997	0.000
U06.8 Emergency use of U06.8	0.003	0.997	0.000
U06.7 Emergency use of U06.7	0.003	0.997	0.000
U06.6 Emergency use of U06.6	0.003	0.997	0.000
U06.5 Emergency use of U06.5	0.003	0.997	0.000
U06.4 Emergency use of U06.4	0.003	0.997	0.000
U06.3 Emergency use of U06.3	0.003	0.997	0.000
U06.2 Emergency use of U06.2	0.003	0.997	0.000
U06.1 Emergency use of U06.1	0.003	0.997	0.000
U06.0 Emergency use of U06.0	0.003	0.997	0.000
U07.9 Emergency use of U07.9	0.003	0.997	0.000
U07.8 Emergency use of U07.8	0.003	0.997	0.000
U07.7 Emergency use of U07.7	0.003	0.997	0.000
U07.6 Emergency use of U07.6	0.003	0.997	0.000
U07.5 Emergency use of U07.5	0.003	0.997	0.000
U07.4 Emergency use of U07.4	0.003	0.997	0.000
U07.3 Emergency use of U07.3	0.003	0.997	0.000
U07.2 Emergency use of U07.2	0.003	0.997	0.000
U07.1 Emergency use of U07.1	0.003	0.997	0.000
U07.0 Emergency use of U07.0	0.003	0.997	0.000
U50.9 Inquest Adjourned Death	0.003	0.997	0.000
U50.3 Level of care administered to neonates (Maximal Intensive Care)	0.003	0.997	0.000
U50.2 Level of care administered to neonates (High Dependancy Intensive Care)	0.003	0.997	0.000
U50.1 Level of care administered to neonates (Special Care)	0.003	0.997	0.000
U50.0 Level of care administered to neonates (Normal Care)	0.003	0.997	0.000
D62 Acute posthaemorrhagic anaemia	0.003	0.997	0.000
S42.20 Fracture of upper end of humerus (closed)	0.003	0.997	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.003	0.997	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.003	0.997	0.000
D25.1 Intramural leiomyoma of uterus	0.000	0.997	0.003
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.997	0.003
G83.1 Monoplegia of lower limb	0.003	0.997	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.003	0.997	0.000
G83.4 Cauda equina syndrome	0.003	0.997	0.000
G83.3 Monoplegia, unspecified	0.003	0.997	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.997	0.003
D60.9 Acquired pure red cell aplasia, unspecified	0.003	0.997	0.000
G83.2 Monoplegia of upper limb	0.003	0.997	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.003	0.997	0.000
S02.6 Fracture of mandible	0.000	0.997	0.003
S02.2 Fracture of nasal bones	0.000	0.997	0.003
C43.8 Overlapping malignant melanoma of skin	0.000	0.997	0.003
C43.0 Malignant melanoma of lip	0.000	0.997	0.003
K44 Diaphragmatic hernia	0.003	0.997	0.000
S42.21 Fracture of upper end of humerus (open)	0.003	0.997	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.003	0.997	0.000
G83.5 Locked-in syndrome	0.003	0.997	0.000
G83.0 Diplegia of upper limbs	0.003	0.997	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.003	0.997	0.000
D60.8 Other acquired pure red cell aplasias	0.003	0.997	0.000
D60.1 Transient acquired pure red cell aplasia	0.003	0.997	0.000
D60.0 Chronic acquired pure red cell aplasia	0.003	0.997	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.003	0.997	0.000
S42.0 Fracture of clavicle	0.003	0.997	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.003	0.997	0.000
S02 Fracture of skull and facial bones	0.000	0.997	0.003
K42 Umbilical hernia	0.003	0.997	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.997	0.003
T21.3 Burn of third degree of trunk	0.003	0.997	0.000
S02.11 Fracture of base of skull (open)	0.000	0.997	0.003
S72.2 Subtrochanteric fracture	0.003	0.997	0.000
D63.0 Anaemia in neoplastic disease	0.003	0.997	0.000
Y42.7 Androgens and anabolic congeners	0.003	0.997	0.000
D82 Immunodeficiency associated with other major defects	0.003	0.997	0.000
S42.1 Fracture of scapula	0.003	0.997	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.997	0.003
D81 Combined immunodeficiencies	0.002	0.997	0.000
G80 Infantile cerebral palsy	0.003	0.997	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.003	0.997	0.000
M06.0 Seronegative rheumatoid arthritis	0.003	0.997	0.000
N19 Unspecified renal failure	0.003	0.997	0.000
D64 Other anaemias	0.003	0.997	0.000
B37.3 Candidiasis of vulva and vagina	0.000	0.997	0.003
C34.1 Upper lobe, bronchus or lung	0.003	0.997	0.000
K65.9 Peritonitis, unspecified	0.002	0.997	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
S72.10 Pertrochanteric fracture (closed)	0.002	0.997	0.000
D83 Common variable immunodeficiency	0.002	0.997	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.002	0.998	0.000
M25.71 Osteophyte (Shoulder region)	0.002	0.998	0.000
G51.3 Clonic hemifacial spasm	0.000	0.998	0.002
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.998	0.002
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
S01.1 Open wound of eyelid and periocular area	0.002	0.998	0.000
M51.9 Intervertebral disk disorder, unspecified	0.000	0.998	0.002
S42.4 Fracture of lower end of humerus	0.002	0.998	0.000
G35 Multiple sclerosis	0.002	0.998	0.000
S02.61 Fracture of mandible (open)	0.000	0.998	0.002
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.002	0.998	0.000
V18.0 Driver injured in nontraffic accident	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
D64.8 Other specified anaemias	0.002	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.000	0.998	0.002
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M06.4 Inflammatory polyarthropathy	0.002	0.998	0.000
M06 Other rheumatoid arthritis	0.002	0.998	0.000
M51 Other intervertebral disk disorders	0.000	0.998	0.002
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.002	0.998	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.002	0.998	0.000
S02.8 Fractures of other skull and facial bones	0.000	0.998	0.002
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
S42.01 Fracture of clavicle (open)	0.002	0.998	0.000
S02.3 Fracture of orbital floor	0.000	0.998	0.002
Y83.3 Surgical operation with formation of external stoma	0.002	0.998	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.998	0.002
G80.9 Infantile cerebral palsy, unspecified	0.002	0.998	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.002	0.998	0.000
E11.0 With coma	0.000	0.998	0.002
K42.1 Umbilical hernia with gangrene	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.002	0.998	0.000
S72.21 Subtrochanteric fracture (open)	0.002	0.998	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.998	0.002
D64.3 Other sideroblastic anaemias	0.002	0.998	0.000
G80.2 Infantile hemiplegia	0.002	0.998	0.000
M06.9 Rheumatoid arthritis, unspecified	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
K22.0 Achalasia of cardia	0.002	0.998	0.000
M35.0 Sicca syndrome [Sjogren]	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.002	0.998	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.998	0.002
G83.8 Other specified paralytic syndromes	0.002	0.998	0.000
S42.11 Fracture of scapula (open)	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
G80.4 Ataxic cerebral palsy	0.002	0.998	0.000
G80.3 Dyskinetic cerebral palsy	0.002	0.998	0.000
K44.1 Diaphragmatic hernia with gangrene	0.002	0.998	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.002	0.998	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.002	0.998	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
T21.0 Burn of unspecified degree of trunk	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.002	0.998	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
D64.4 Congenital dyserythropoietic anaemia	0.002	0.998	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.002	0.998	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.002	0.998	0.000
D64.0 Hereditary sideroblastic anaemia	0.002	0.998	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.998	0.002
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.000	0.998	0.002
S72.1 Pertrochanteric fracture	0.002	0.998	0.000
J84 Other interstitial pulmonary diseases	0.002	0.998	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.002	0.998	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
D84 Other immunodeficiencies	0.002	0.998	0.000
K65.0 Acute peritonitis	0.002	0.998	0.000
M06.1 Adult-onset Still's disease	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
M06.8 Other specified rheumatoid arthritis	0.002	0.998	0.000
D37.0 Lip, oral cavity and pharynx	0.002	0.998	0.000
G80.1 Spastic diplegia	0.002	0.998	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.998	0.002
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.998	0.002
S22.50 Flail chest (closed)	0.000	0.998	0.002
M51.3 Other specified intervertebral disk degeneration	0.000	0.998	0.002
S06.5 Traumatic subdural haemorrhage	0.000	0.998	0.002
S22.4 Multiple fractures of ribs	0.000	0.998	0.002
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.998	0.002
C43.5 Malignant melanoma of trunk	0.000	0.998	0.002
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
S83.2 Tear of meniscus, current	0.000	0.998	0.002
T21 Burn and corrosion of trunk	0.002	0.998	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
L43.9 Lichen planus, unspecified	0.002	0.998	0.000
S02.5 Fracture of tooth	0.000	0.998	0.002
S49.9 Unspecified injury of shoulder and upper arm	0.002	0.998	0.000
G20 Parkinson's disease	0.000	0.998	0.002
M51.4 Schmorl's nodes	0.000	0.998	0.002
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
D86 Sarcoidosis	0.002	0.998	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
G80.8 Other infantile cerebral palsy	0.002	0.998	0.000
G80.0 Spastic cerebral palsy	0.002	0.998	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
S05.1 Contusion of eyeball and orbital tissues	0.002	0.998	0.000
Z12.5 Special screening examination for neoplasm of prostate	0.000	0.998	0.002
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.002	0.998	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.002	0.998	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.002	0.998	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.002	0.998	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.002	0.998	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.002	0.998	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.002	0.998	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.002	0.998	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.000	0.998	0.002
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.998	0.002
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.998	0.002
Y42.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
S02.81 Fractures of other skull and facial bones (open)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations