TreeWAS – Variant ID: rs4774830

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K51 Ulcerative colitis	0.283	0.717	0.000
E10.9 Without complications	0.279	0.721	0.000
K50-K52 Noninfective enteritis and colitis	0.279	0.721	0.000
K50 Crohn's disease [regional enteritis]	0.278	0.722	0.000
K51.4 Pseudopolyposis of colon	0.271	0.729	0.000
K70-K77 Diseases of liver	0.270	0.730	0.000
K51.9 Ulcerative colitis, unspecified	0.269	0.731	0.000
K50.1 Crohn's disease of large intestine	0.268	0.732	0.000
K74 Fibrosis and cirrhosis of liver	0.262	0.738	0.000
K50.9 Crohn's disease, unspecified	0.259	0.741	0.000
K70 Alcoholic liver disease	0.257	0.742	0.000
E10 Insulin-dependent diabetes mellitus	0.257	0.743	0.000
K51.2 Ulcerative (chronic) proctitis	0.244	0.756	0.000
K73 Chronic hepatitis, not elsewhere classified	0.243	0.757	0.000
K74.6 Other and unspecified cirrhosis of liver	0.243	0.757	0.000
Chapter XI Diseases of the digestive system	0.233	0.767	0.000
K74.3 Primary biliary cirrhosis	0.232	0.768	0.000
K70.3 Alcoholic cirrhosis of liver	0.230	0.770	0.000
K75 Other inflammatory liver diseases	0.229	0.771	0.000
K72 Hepatic failure, not elsewhere classified	0.228	0.772	0.000
E10.3 With ophthalmic complications	0.226	0.774	0.000
K70.9 Alcoholic liver disease, unspecified	0.224	0.776	0.000
K73.9 Chronic hepatitis, unspecified	0.223	0.777	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.220	0.780	0.000
K86 Other diseases of pancreas	0.217	0.783	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.217	0.783	0.000
E10.2 With renal complications	0.209	0.791	0.000
K70.0 Alcoholic fatty liver	0.209	0.791	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.206	0.794	0.000
K86.9 Disease of pancreas, unspecified	0.206	0.794	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.203	0.797	0.000
E10.8 With unspecified complications	0.203	0.797	0.000
K72.9 Hepatic failure, unspecified	0.202	0.798	0.000
E10.4 With neurological complications	0.202	0.798	0.000
K50.8 Other Crohn's disease	0.201	0.798	0.000
K51.5 Mucosal proctocolitis	0.201	0.799	0.000
K50.0 Crohn's disease of small intestine	0.200	0.800	0.000
K74.0 Hepatic fibrosis	0.200	0.800	0.000
K65-K67 Diseases of peritoneum	0.198	0.802	0.000
K75.8 Other specified inflammatory liver diseases	0.196	0.804	0.000
K77 Liver disorders in diseases classified elsewhere	0.194	0.806	0.000
K71 Toxic liver disease	0.194	0.806	0.000
K86.8 Other specified diseases of pancreas	0.193	0.807	0.000
K70.1 Alcoholic hepatitis	0.190	0.810	0.000
K74.5 Biliary cirrhosis, unspecified	0.188	0.812	0.000
K74.4 Secondary biliary cirrhosis	0.188	0.812	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.188	0.812	0.000
K74.1 Hepatic sclerosis	0.188	0.812	0.000
K76 Other diseases of liver	0.188	0.812	0.000
E10-E14 Diabetes mellitus	0.186	0.814	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.185	0.815	0.000
E10.7 With multiple complications	0.185	0.815	0.000
E10.6 With other specified complications	0.185	0.815	0.000
E10.0 With coma	0.185	0.815	0.000
K75.4 Autoimmune hepatitis	0.184	0.816	0.000
K82 Other diseases of gallbladder	0.184	0.816	0.000
K66 Other disorders of peritoneum	0.183	0.817	0.000
K86.2 Cyst of pancreas	0.182	0.818	0.000
E10.5 With peripheral circulatory complications	0.182	0.818	0.000
K76.6 Portal hypertension	0.181	0.819	0.000
K83 Other diseases of biliary tract	0.175	0.825	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.174	0.826	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.174	0.826	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.174	0.826	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.174	0.826	0.000
E11 Non-insulin-dependent diabetes mellitus	0.174	0.826	0.000
K51.8 Other ulcerative colitis	0.173	0.827	0.000
K66.0 Peritoneal adhesions	0.172	0.828	0.000
K70.4 Alcoholic hepatic failure	0.168	0.832	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.165	0.834	0.000
K86.1 Other chronic pancreatitis	0.165	0.835	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.164	0.836	0.000
K75.2 Nonspecific reactive hepatitis	0.164	0.836	0.000
K75.1 Phlebitis of portal vein	0.164	0.836	0.000
K72.1 Chronic hepatic failure	0.163	0.836	0.000
E10.1 With ketoacidosis	0.163	0.837	0.000
K82.8 Other specified diseases of gallbladder	0.162	0.838	0.000
E11.5 With peripheral circulatory complications	0.157	0.843	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.156	0.844	0.000
K75.9 Inflammatory liver disease, unspecified	0.155	0.845	0.000
K75.0 Abscess of liver	0.154	0.846	0.000
K72.0 Acute and subacute hepatic failure	0.151	0.849	0.000
K86.3 Pseudocyst of pancreas	0.150	0.849	0.000
E11.2 With renal complications	0.144	0.856	0.000
E11.4 With neurological complications	0.143	0.857	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.142	0.857	0.000
K71.9 Toxic liver disease, unspecified	0.139	0.861	0.000
K71.8 Toxic liver disease with other disorders of liver	0.139	0.861	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.139	0.861	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.139	0.861	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.139	0.861	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.139	0.861	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.139	0.861	0.000
K71.2 Toxic liver disease with acute hepatitis	0.139	0.861	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.139	0.861	0.000
K71.0 Toxic liver disease with cholestasis	0.139	0.861	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.139	0.861	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.139	0.861	0.000
K83.1 Obstruction of bile duct	0.139	0.861	0.000
K85 Acute pancreatitis	0.136	0.864	0.000
K82.9 Disease of gallbladder, unspecified	0.136	0.864	0.000
K76.7 Hepatorenal syndrome	0.135	0.865	0.000
K76.5 Hepatic veno-occlusive disease	0.135	0.865	0.000
K76.4 Peliosis hepatis	0.135	0.865	0.000
K76.3 Infarction of liver	0.135	0.865	0.000
K76.2 Central haemorrhagic necrosis of liver	0.135	0.865	0.000
K76.1 Chronic passive congestion of liver	0.135	0.865	0.000
K66.8 Other specified disorders of peritoneum	0.135	0.865	0.000
K83.0 Cholangitis	0.134	0.865	0.000
E12 Malnutrition-related diabetes mellitus	0.133	0.866	0.000
K82.3 Fistula of gallbladder	0.132	0.868	0.000
K82.2 Perforation of gallbladder	0.132	0.868	0.000
K82.0 Obstruction of gallbladder	0.132	0.868	0.000
K66.9 Disorder of peritoneum, unspecified	0.131	0.868	0.000
K66.1 Haemoperitoneum	0.131	0.868	0.000
E11.8 With unspecified complications	0.131	0.869	0.000
K82.4 Cholesterolosis of gallbladder	0.129	0.870	0.000
K83.9 Disease of biliary tract, unspecified	0.125	0.875	0.000
K83.5 Biliary cyst	0.125	0.875	0.000
K83.4 Spasm of sphincter of Oddi	0.125	0.875	0.000
K83.3 Fistula of bile duct	0.125	0.875	0.000
K83.2 Perforation of bile duct	0.125	0.875	0.000
K82.1 Hydrops of gallbladder	0.125	0.875	0.000
E11.7 With multiple complications	0.125	0.875	0.000
E11.0 With coma	0.125	0.875	0.000
E13 Other specified diabetes mellitus	0.124	0.876	0.000
K83.8 Other specified diseases of biliary tract	0.122	0.878	0.000
E11.1 With ketoacidosis	0.121	0.879	0.000
K52 Other non-infective gastro-enteritis and colitis	0.121	0.879	0.000
E11.3 With ophthalmic complications	0.120	0.880	0.000
E11.6 With other specified complications	0.117	0.883	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.117	0.883	0.000
E11.9 Without complications	0.116	0.884	0.000
K35-K38 Diseases of appendix	0.113	0.886	0.000
K76.9 Liver disease, unspecified	0.113	0.887	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.112	0.888	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.112	0.888	0.000
K65 Peritonitis	0.110	0.890	0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.102	0.898	0.000
K67.3 Tuberculous peritonitis	0.102	0.898	0.000
K67.2 Syphilitic peritonitis	0.102	0.898	0.000
K67.1 Gonococcal peritonitis	0.102	0.898	0.000
K67.0 Chlamydial peritonitis	0.102	0.898	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.101	0.899	0.000
K76.8 Other specified diseases of liver	0.099	0.901	0.000
K85.8 Other acute pancreatitis	0.098	0.902	0.000
K85.3 Drug-induced acute pancreatitis	0.098	0.902	0.000
K85.2 Alcohol-induced acute pancreatitis	0.098	0.902	0.000
K85.0 Idiopathic acute pancreatitis	0.098	0.902	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.097	0.903	0.000
E12.9 Without complications	0.096	0.904	0.000
E12.8 With unspecified complications	0.096	0.904	0.000
E12.7 With multiple complications	0.096	0.904	0.000
E12.6 With other specified complications	0.096	0.904	0.000
E12.5 With peripheral circulatory complications	0.096	0.904	0.000
E12.4 With neurological complications	0.096	0.904	0.000
E12.3 With ophthalmic complications	0.096	0.904	0.000
E12.2 With renal complications	0.096	0.904	0.000
E12.1 With ketoacidosis	0.096	0.904	0.000
E12.0 With coma	0.096	0.904	0.000
K85.9 Acute pancreatitis, unspecified	0.095	0.905	0.000
E14 Unspecified diabetes mellitus	0.094	0.906	0.000
K11 Diseases of salivary glands	0.094	0.906	0.000
K10 Other diseases of jaws	0.091	0.909	0.000
K02 Dental caries	0.090	0.910	0.000
E13.8 With unspecified complications	0.089	0.911	0.000
E13.7 With multiple complications	0.089	0.911	0.000
E13.6 With other specified complications	0.089	0.911	0.000
E13.5 With peripheral circulatory complications	0.089	0.911	0.000
E13.4 With neurological complications	0.089	0.911	0.000
E13.3 With ophthalmic complications	0.089	0.911	0.000
E13.2 With renal complications	0.089	0.911	0.000
E13.1 With ketoacidosis	0.089	0.911	0.000
E13.0 With coma	0.089	0.911	0.000
K01 Embedded and impacted teeth	0.089	0.911	0.000
K05 Gingivitis and periodontal diseases	0.089	0.911	0.000
K13 Other diseases of lip and oral mucosa	0.087	0.913	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.087	0.913	0.000
K52.3 Indeterminate colitis	0.085	0.914	0.000
K38 Other diseases of appendix	0.084	0.916	0.000
K65.9 Peritonitis, unspecified	0.084	0.916	0.000
K03 Other diseases of hard tissues of teeth	0.084	0.916	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.084	0.916	0.000
K85.1 Biliary acute pancreatitis	0.083	0.917	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.082	0.918	0.000
K36 Other appendicitis	0.081	0.918	0.000
K00 Disorders of tooth development and eruption	0.081	0.919	0.000
K11.5 Sialolithiasis	0.081	0.919	0.000
E13.9 Without complications	0.079	0.920	0.000
K12 Stomatitis and related lesions	0.077	0.922	0.000
K13.0 Diseases of lips	0.075	0.925	0.000
K10.8 Other specified diseases of jaws	0.075	0.925	0.000
K37 Unspecified appendicitis	0.074	0.926	0.000
K52.1 Toxic gastro-enteritis and colitis	0.074	0.926	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.073	0.926	0.000
K08 Other disorders of teeth and supporting structures	0.073	0.927	0.000
K05.3 Chronic periodontitis	0.072	0.928	0.000
E20-E35 Disorders of other endocrine glands	0.072	0.928	0.000
K90-K93 Other diseases of the digestive system	0.071	0.929	0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.070	0.930	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.070	0.930	0.000
K06.1 Gingival enlargement	0.070	0.930	0.000
K06.0 Gingival recession	0.070	0.930	0.000
E70-E90 Metabolic disorders	0.069	0.931	0.000
K02.9 Dental caries, unspecified	0.069	0.931	0.000
K01.1 Impacted teeth	0.069	0.931	0.000
K11.9 Disease of salivary gland, unspecified	0.068	0.932	0.000
K65.8 Other peritonitis	0.068	0.932	0.000
E14.8 With unspecified complications	0.068	0.932	0.000
E14.7 With multiple complications	0.068	0.932	0.000
E14.6 With other specified complications	0.068	0.932	0.000
E14.5 With peripheral circulatory complications	0.068	0.932	0.000
E14.4 With neurological complications	0.068	0.932	0.000
E14.2 Withrenal complications	0.068	0.932	0.000
E14.1 With ketoacidosis	0.068	0.932	0.000
E14.0 With coma	0.068	0.932	0.000
K02.8 Other dental caries	0.067	0.932	0.000
K11.7 Disturbances of salivary secretion	0.067	0.933	0.000
K11.6 Mucocele of salivary gland	0.067	0.933	0.000
K11.4 Fistula of salivary gland	0.067	0.933	0.000
K11.3 Abscess of salivary gland	0.067	0.933	0.000
K11.1 Hypertrophy of salivary gland	0.067	0.933	0.000
K11.0 Atrophy of salivary gland	0.067	0.933	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.066	0.934	0.000
E40-E46 Malnutrition	0.066	0.934	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.066	0.934	0.000
K11.8 Other diseases of salivary glands	0.066	0.934	0.000
K10.9 Disease of jaws, unspecified	0.066	0.934	0.000
K10.3 Alveolitis of jaws	0.066	0.934	0.000
K10.1 Giant cell granuloma, central	0.066	0.934	0.000
K10.0 Developmental disorders of jaws	0.066	0.934	0.000
K02.5 Caries with pulp exposure	0.065	0.935	0.000
K02.4 Odontoclasia	0.065	0.935	0.000
K02.3 Arrested dental caries	0.065	0.935	0.000
K02.2 Caries of cementum	0.065	0.935	0.000
K02.1 Caries of dentin	0.065	0.935	0.000
K02.0 Caries limited to enamel	0.065	0.935	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.064	0.936	0.000
K01.0 Embedded teeth	0.064	0.936	0.000
K05.2 Acute periodontitis	0.064	0.936	0.000
K05.5 Other periodontal diseases	0.064	0.936	0.000
K05.4 Periodontosis	0.064	0.936	0.000
K05.1 Chronic gingivitis	0.064	0.936	0.000
K05.0 Acute gingivitis	0.064	0.936	0.000
K07 Dentofacial anomalies [including malocclusion]	0.063	0.936	0.000
K38.8 Other specified diseases of appendix	0.063	0.937	0.000
K81 Cholecystitis	0.063	0.937	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.063	0.937	0.000
K13.5 Oral submucous fibrosis	0.063	0.937	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.063	0.937	0.000
K13.3 Hairy leukoplakia	0.063	0.937	0.000
K13.1 Cheek and lip biting	0.063	0.937	0.000
K10.2 Inflammatory conditions of jaws	0.062	0.937	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.062	0.938	0.000
K14 Diseases of tongue	0.062	0.938	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.062	0.938	0.000
K09 Cysts of oral region, not elsewhere classified	0.061	0.938	0.000
E14.9 Without complications	0.061	0.939	0.000
K38.9 Disease of appendix, unspecified	0.060	0.939	0.000
K38.3 Fistula of appendix	0.060	0.939	0.000
K38.2 Diverticulum of appendix	0.060	0.939	0.000
K38.1 Appendicular concretions	0.060	0.939	0.000
K38.0 Hyperplasia of appendix	0.060	0.939	0.000
K03.9 Disease of hard tissues of teeth, unspecified	0.060	0.939	0.000
K03.8 Other specified diseases of hard tissues of teeth	0.060	0.939	0.000
K03.7 Posteruptive colour changes of dental hard tissues	0.060	0.939	0.000
K03.6 Deposits [accretions] on teeth	0.060	0.939	0.000
K03.5 Ankylosis of teeth	0.060	0.939	0.000
K03.4 Hypercementosis	0.060	0.939	0.000
K03.3 Pathological resorption of teeth	0.060	0.939	0.000
K03.2 Erosion of teeth	0.060	0.939	0.000
K03.1 Abrasion of teeth	0.060	0.939	0.000
K03.0 Excessive attrition of teeth	0.060	0.939	0.000
K11.2 Sialoadenitis	0.060	0.940	0.000
E50-E64 Other nutritional deficiencies	0.060	0.940	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.060	0.940	0.000
K05.6 Periodontal disease, unspecified	0.059	0.941	0.000
K04 Diseases of pulp and periapical tissues	0.059	0.941	0.000
K00.9 Disorder of tooth development, unspecified	0.058	0.942	0.000
K00.8 Other disorders of tooth development	0.058	0.942	0.000
K00.7 Teething syndrome	0.058	0.942	0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.058	0.942	0.000
K00.4 Disturbances in tooth formation	0.058	0.942	0.000
K00.3 Mottled teeth	0.058	0.942	0.000
K00.2 Abnormalities of size and form of teeth	0.058	0.942	0.000
K00.1 Supernumerary teeth	0.058	0.942	0.000
K00.0 Anodontia	0.058	0.942	0.000
E87.5 Hyperkalaemia	0.058	0.942	0.000
E27 Other disorders of adrenal gland	0.057	0.943	0.000
E34 Other endocrine disorders	0.057	0.943	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.057	0.943	0.000
E83 Disorders of mineral metabolism	0.057	0.943	0.000
E24 Cushing's syndrome	0.056	0.943	0.000
K12.1 Other forms of stomatitis	0.056	0.944	0.000
K12.3 Oral mucositis (ulcerative)	0.056	0.944	0.000
K12.0 Recurrent oral aphthae	0.056	0.944	0.000
K00.6 Disturbances in tooth eruption	0.055	0.945	0.000
K65.0 Acute peritonitis	0.055	0.945	0.000
E74 Other disorders of carbohydrate metabolism	0.054	0.946	0.000
E46 Unspecified protein-energy malnutrition	0.053	0.946	0.000
E22 Hyperfunction of pituitary gland	0.053	0.947	0.000
E83.3 Disorders of phosphorus metabolism	0.053	0.947	0.000
E16 Other disorders of pancreatic internal secretion	0.053	0.947	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.052	0.947	0.000
E88 Other metabolic disorders	0.052	0.948	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.051	0.948	0.000
E32 Diseases of thymus	0.051	0.948	0.000
E31 Polyglandular dysfunction	0.051	0.948	0.000
E30 Disorders of puberty, not elsewhere classified	0.051	0.948	0.000
E26 Hyperaldosteronism	0.051	0.948	0.000
E25 Adrenogenital disorders	0.051	0.948	0.000
E20 Hypoparathyroidism	0.051	0.948	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.051	0.949	0.000
E21.3 Hyperparathyroidism, unspecified	0.051	0.949	0.000
E21.0 Primary hyperparathyroidism	0.050	0.949	0.000
E73 Lactose intolerance	0.050	0.950	0.000
E85 Amyloidosis	0.050	0.950	0.000
E84 Cystic fibrosis	0.050	0.950	0.000
E79 Disorders of purine and pyrimidine metabolism	0.050	0.950	0.000
E77 Disorders of glycoprotein metabolism	0.050	0.950	0.000
E76 Disorders of glycosaminoglycan metabolism	0.050	0.950	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.050	0.950	0.000
E72 Other disorders of amino-acid metabolism	0.050	0.950	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.050	0.950	0.000
E70 Disorders of aromatic amino-acid metabolism	0.050	0.950	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.050	0.950	0.000
E86 Volume depletion	0.050	0.950	0.000
K12.2 Cellulitis and abscess of mouth	0.048	0.951	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.049	0.951	0.000
K04.7 Periapical abscess without sinus	0.048	0.952	0.000
E29 Testicular dysfunction	0.048	0.952	0.000
E87.0 Hyperosmolality and hypernatraemia	0.048	0.952	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.048	0.952	0.000
E45 Retarded development following protein-energy malnutrition	0.048	0.952	0.000
E43 Unspecified severe protein-energy malnutrition	0.048	0.952	0.000
E42 Marasmic kwashiorkor	0.048	0.952	0.000
E41 Nutritional marasmus	0.048	0.952	0.000
E40 Kwashiorkor	0.048	0.952	0.000
E15 Nondiabetic hypoglycaemic coma	0.047	0.952	0.000
E87.3 Alkalosis	0.047	0.953	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.047	0.953	0.000
E83.1 Disorders of iron metabolism	0.047	0.953	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.047	0.953	0.000
E87.4 Mixed disorder of acid-base balance	0.046	0.954	0.000
K14.9 Disease of tongue, unspecified	0.046	0.954	0.000
K05.22 Aggressive periodontitis, generalized	0.046	0.954	0.000
K07.9 Dentofacial anomaly, unspecified	0.046	0.954	0.000
K07.8 Other dentofacial anomalies	0.046	0.954	0.000
K07.5 Dentofacial functional abnormalities	0.046	0.954	0.000
K07.4 Malocclusion, unspecified	0.046	0.954	0.000
K07.2 Anomalies of dental arch relationship	0.046	0.954	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.046	0.954	0.000
K07.0 Major anomalies of jaw size	0.046	0.954	0.000
K04.0 Pulpitis	0.046	0.954	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.046	0.954	0.000
E24.9 Cushing's syndrome, unspecified	0.046	0.954	0.000
K81.8 Other cholecystitis	0.045	0.954	0.000
K13.29 Other disturbances of oral epithelium, including tongue	0.045	0.955	0.000
E34.0 Carcinoid syndrome	0.045	0.955	0.000
E87.6 Hypokalaemia	0.045	0.955	0.000
E87.2 Acidosis	0.045	0.955	0.000
K14.6 Glossodynia	0.045	0.955	0.000
K14.5 Plicated tongue	0.045	0.955	0.000
K14.4 Atrophy of tongue papillae	0.045	0.955	0.000
K14.3 Hypertrophy of tongue papillae	0.045	0.955	0.000
K14.2 Median rhomboid glossitis	0.045	0.955	0.000
K14.1 Geographic tongue	0.045	0.955	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.044	0.955	0.000
E21.4 Other specified disorders of parathyroid gland	0.044	0.955	0.000
E21.2 Other hyperparathyroidism	0.044	0.955	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.044	0.955	0.000
K09.9 Cyst of oral region, unspecified	0.044	0.956	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.044	0.956	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.044	0.956	0.000
E55 Vitamin D deficiency	0.044	0.956	0.000
E61 Deficiency of other nutrient elements	0.044	0.956	0.000
E16.2 Hypoglycaemia, unspecified	0.044	0.956	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.044	0.956	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.043	0.956	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.043	0.957	0.000
E63 Other nutritional deficiencies	0.043	0.957	0.000
E56 Other vitamin deficiencies	0.043	0.957	0.000
E51 Thiamine deficiency	0.043	0.957	0.000
E50 Vitamin A deficiency	0.043	0.957	0.000
E60 Dietary zinc deficiency	0.043	0.957	0.000
E59 Dietary selenium deficiency	0.043	0.957	0.000
E58 Dietary calcium deficiency	0.043	0.957	0.000
E54 Ascorbic acid deficiency	0.043	0.957	0.000
E52 Niacin deficiency [pellagra]	0.043	0.957	0.000
E34.9 Endocrine disorder, unspecified	0.043	0.957	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.043	0.957	0.000
E23 Hypofunction and other disorders of pituitary gland	0.042	0.957	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.042	0.957	0.000
E65-E68 Obesity and other hyperalimentation	0.042	0.957	0.000
E28 Ovarian dysfunction	0.042	0.958	0.000
K04.3 Abnormal hard tissue formation in pulp	0.042	0.958	0.000
K04.2 Pulp degeneration	0.042	0.958	0.000
K04.1 Necrosis of pulp	0.042	0.958	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.042	0.958	0.000
K40-K46 Hernia	0.042	0.958	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.042	0.958	0.000
E14.3 With ophthalmic complications	0.041	0.958	0.001
E27.1 Primary adrenocortical insufficiency	0.042	0.958	0.000
K04.6 Periapical abscess with sinus	0.042	0.958	0.000
E27.9 Disorder of adrenal gland, unspecified	0.041	0.959	0.000
E27.8 Other specified disorders of adrenal gland	0.041	0.959	0.000
E27.5 Adrenomedullary hyperfunction	0.041	0.959	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.041	0.959	0.000
E27.2 Addisonian crisis	0.041	0.959	0.000
E27.0 Other adrenocortical overactivity	0.041	0.959	0.000
E34.8 Other specified endocrine disorders	0.041	0.959	0.000
E34.5 Androgen resistance syndrome	0.041	0.959	0.000
E34.4 Constitutional tall stature	0.041	0.959	0.000
E34.3 Short stature, not elsewhere classified	0.041	0.959	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.041	0.959	0.000
E34.1 Other hypersecretion of intestinal hormones	0.041	0.959	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.041	0.959	0.000
E83.8 Other disorders of mineral metabolism	0.041	0.959	0.000
E83.2 Disorders of zinc metabolism	0.041	0.959	0.000
E83.0 Disorders of copper metabolism	0.041	0.959	0.000
E24.8 Other Cushing's syndrome	0.041	0.959	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.041	0.959	0.000
E24.3 Ectopic ACTH syndrome	0.041	0.959	0.000
E24.2 Drug-induced Cushing's syndrome	0.041	0.959	0.000
E24.1 Nelson's syndrome	0.041	0.959	0.000
E24.0 Pituitary-dependent Cushing's disease	0.041	0.959	0.000
K07.6 Temporomandibular joint disorders	0.041	0.959	0.000
E53 Deficiency of other B group vitamins	0.040	0.960	0.000
K14.0 Glossitis	0.040	0.960	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.039	0.960	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.039	0.961	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.039	0.961	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.039	0.961	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.039	0.961	0.000
E74.2 Disorders of galactose metabolism	0.039	0.961	0.000
E74.1 Disorders of fructose metabolism	0.039	0.961	0.000
E74.0 Glycogen storage disease	0.039	0.961	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.038	0.961	0.000
E22.8 Other hyperfunction of pituitary gland	0.038	0.961	0.000
E22.1 Hyperprolactinaemia	0.038	0.961	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.038	0.962	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.038	0.962	0.000
E16.4 Abnormal secretion of gastrin	0.038	0.962	0.000
E16.3 Increased secretion of glucagon	0.038	0.962	0.000
E16.1 Other hypoglycaemia	0.038	0.962	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.038	0.962	0.000
K35 Acute appendicitis	0.037	0.962	0.001
E88.9 Metabolic disorder, unspecified	0.037	0.963	0.000
E88.8 Other specified metabolic disorders	0.037	0.963	0.000
E88.3 Tumour lysis syndrome	0.037	0.963	0.000
E88.2 Lipomatosis, not elsewhere classified	0.037	0.963	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.037	0.963	0.000
E20.9 Hypoparathyroidism, unspecified	0.037	0.963	0.000
E20.8 Other hypoparathyroidism	0.037	0.963	0.000
E20.1 Pseudohypoparathyroidism	0.037	0.963	0.000
E20.0 Idiopathic hypoparathyroidism	0.037	0.963	0.000
E25.9 Adrenogenital disorder, unspecified	0.037	0.963	0.000
E25.8 Other adrenogenital disorders	0.037	0.963	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.037	0.963	0.000
E26.9 Hyperaldosteronism, unspecified	0.037	0.963	0.000
E26.8 Other hyperaldosteronism	0.037	0.963	0.000
E26.1 Secondary hyperaldosteronism	0.037	0.963	0.000
E26.0 Primary hyperaldosteronism	0.037	0.963	0.000
E30.9 Disorder of puberty, unspecified	0.037	0.963	0.000
E30.8 Other disorders of puberty	0.037	0.963	0.000
E30.1 Precocious puberty	0.037	0.963	0.000
E30.0 Delayed puberty	0.037	0.963	0.000
E31.9 Polyglandular dysfunction, unspecified	0.037	0.963	0.000
E31.8 Other polyglandular dysfunction	0.037	0.963	0.000
E31.1 Polyglandular hyperfunction	0.037	0.963	0.000
E31.0 Autoimmune polyglandular failure	0.037	0.963	0.000
E32.9 Disease of thymus, unspecified	0.037	0.963	0.000
E32.8 Other diseases of thymus	0.037	0.963	0.000
E32.1 Abscess of thymus	0.037	0.963	0.000
E32.0 Persistent hyperplasia of thymus	0.037	0.963	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.037	0.963	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.037	0.963	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.037	0.963	0.000
K09.2 Other cysts of jaw	0.036	0.963	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.037	0.963	0.000
K93.1 Megacolon in Chagas' disease	0.037	0.963	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.037	0.963	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.037	0.963	0.000
E73.9 Lactose intolerance, unspecified	0.036	0.964	0.000
E73.8 Other lactose intolerance	0.036	0.964	0.000
E73.1 Secondary lactase deficiency	0.036	0.964	0.000
E73.0 Congenital lactase deficiency	0.036	0.964	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.036	0.964	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.036	0.964	0.000
E70.3 Albinism	0.036	0.964	0.000
E70.2 Disorders of tyrosine metabolism	0.036	0.964	0.000
E70.1 Other hyperphenylalaninaemias	0.036	0.964	0.000
E70.0 Classical phenylketonuria	0.036	0.964	0.000
E71.3 Disorders of fatty-acid metabolism	0.036	0.964	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.036	0.964	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.036	0.964	0.000
E71.0 Maple-syrup-urine disease	0.036	0.964	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.036	0.964	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.036	0.964	0.000
E72.5 Disorders of glycine metabolism	0.036	0.964	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations