TreeWAS – Variant ID: rs4814176

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.758	0.242
K80 Cholelithiasis	0.000	0.771	0.229
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.771	0.229
K80.8 Other cholelithiasis	0.000	0.798	0.202
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.808	0.192
K80.3 Calculus of bile duct with cholangitis	0.000	0.835	0.165
K86 Other diseases of pancreas	0.000	0.855	0.145
K86.3 Pseudocyst of pancreas	0.000	0.856	0.144
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.856	0.144
K86.8 Other specified diseases of pancreas	0.000	0.873	0.127
K85 Acute pancreatitis	0.000	0.881	0.119
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.882	0.118
K86.1 Other chronic pancreatitis	0.000	0.884	0.116
K85.1 Biliary acute pancreatitis	0.000	0.892	0.108
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.892	0.108
D68.9 Coagulation defect, unspecified	0.000	0.894	0.106
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.896	0.104
D68 Other coagulation defects	0.000	0.897	0.103
D68.6 Other Thrombophilia	0.000	0.901	0.099
K86.2 Cyst of pancreas	0.000	0.904	0.096
K85.2 Alcohol-induced acute pancreatitis	0.000	0.905	0.095
B07 Viral warts	0.000	0.907	0.093
K85.8 Other acute pancreatitis	0.000	0.912	0.088
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.915	0.085
K82 Other diseases of gallbladder	0.000	0.915	0.085
D68.2 Hereditary deficiency of other clotting factors	0.000	0.917	0.083
D69 Purpura and other haemorrhagic conditions	0.000	0.918	0.082
D68.5 Primary Thrombophilia	0.000	0.918	0.082
D68.8 Other specified coagulation defects	0.000	0.919	0.081
K85.3 Drug-induced acute pancreatitis	0.000	0.920	0.079
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.921	0.079
K85.0 Idiopathic acute pancreatitis	0.000	0.924	0.076
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.925	0.074
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.925	0.074
K82.0 Obstruction of gallbladder	0.000	0.927	0.073
D69.4 Other primary thrombocytopenia	0.000	0.930	0.070
D68.0 Von Willebrand's disease	0.000	0.930	0.070
K86.9 Disease of pancreas, unspecified	0.000	0.930	0.070
K82.2 Perforation of gallbladder	0.000	0.931	0.069
D66 Hereditary factor VIII deficiency	0.000	0.933	0.067
D69.9 Haemorrhagic condition, unspecified	0.000	0.933	0.066
D68.4 Acquired coagulation factor deficiency	0.000	0.934	0.066
D69.8 Other specified haemorrhagic conditions	0.000	0.936	0.064
K82.3 Fistula of gallbladder	0.000	0.937	0.063
K85.9 Acute pancreatitis, unspecified	0.000	0.938	0.062
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.938	0.062
M13.96 Arthritis, unspecified (Lower leg)	0.000	0.939	0.061
D68.1 Hereditary factor XI deficiency	0.000	0.940	0.060
D69.2 Other nonthrombocytopenic purpura	0.000	0.940	0.060
D69.6 Thrombocytopenia, unspecified	0.000	0.941	0.059
D67 Hereditary factor IX deficiency	0.000	0.942	0.058
K82.9 Disease of gallbladder, unspecified	0.000	0.943	0.057
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.944	0.056
K80.4 Calculus of bile duct with cholecystitis	0.000	0.944	0.056
D69.1 Qualitative platelet defects	0.000	0.947	0.053
K82.1 Hydrops of gallbladder	0.000	0.951	0.049
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.000	0.952	0.048
D69.0 Allergic purpura	0.000	0.953	0.047
K82.4 Cholesterolosis of gallbladder	0.000	0.954	0.046
D69.5 Secondary thrombocytopenia	0.000	0.956	0.043
B02 Zoster [herpes zoster]	0.000	0.957	0.043
K81 Cholecystitis	0.000	0.962	0.038
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.000	0.964	0.036
B02.3 Zoster ocular disease	0.000	0.964	0.036
B01 Varicella [chickenpox]	0.000	0.964	0.035
B02.2 Zoster with other nervous system involvement	0.000	0.964	0.035
B06 Rubella [German measles]	0.000	0.965	0.035
B05 Measles	0.000	0.965	0.035
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.000	0.965	0.035
B04 Monkeypox	0.000	0.965	0.035
B03 Smallpox	0.000	0.965	0.035
K81.8 Other cholecystitis	0.000	0.966	0.034
B02.9 Zoster without complication	0.000	0.966	0.034
K82.8 Other specified diseases of gallbladder	0.000	0.967	0.033
B02.1 Zoster meningitis	0.000	0.969	0.031
B02.7 Disseminated zoster	0.000	0.969	0.031
B02.0 Zoster encephalitis	0.000	0.969	0.031
B01.8 Varicella with other complications	0.000	0.971	0.029
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.972	0.028
B08.1 Molluscum contagiosum	0.000	0.973	0.027
B02.8 Zoster with other complications	0.000	0.973	0.027
B01.9 Varicella without complications	0.000	0.973	0.027
B08.8 Other specified viral infections characterised by skin and mucous membrane lesions	0.000	0.974	0.026
B08.5 Enteroviral vesicular pharyngitis	0.000	0.974	0.026
B08.4 Enteroviral vesicular stomatitis with exanthem	0.000	0.974	0.026
B08.3 Erythema infectiosum [fifth disease]	0.000	0.974	0.026
B08.2 Exanthema subitum [sixth disease]	0.000	0.974	0.026
B08.0 Other orthopoxvirus infections	0.000	0.974	0.026
B01.1 Varicella encephalitis	0.000	0.974	0.026
B05.9 Measles without complication	0.000	0.975	0.025
B05.8 Measles with other complications	0.000	0.975	0.025
B05.4 Measles with intestinal complications	0.000	0.975	0.025
B05.3 Measles complicated by otitis media	0.000	0.975	0.025
B05.2 Measles complicated by pneumonia	0.000	0.975	0.025
B05.1 Measles complicated by meningitis	0.000	0.975	0.025
B05.0 Measles complicated by encephalitis	0.000	0.975	0.025
B06.9 Rubella without complication	0.000	0.975	0.025
B06.8 Rubella with other complications	0.000	0.975	0.025
B06.0 Rubella with neurological complications	0.000	0.975	0.025
B01.0 Varicella meningitis	0.000	0.975	0.025
B00 Herpesviral [herpes simplex] infections	0.000	0.978	0.022
B01.2 Varicella pneumonia	0.000	0.978	0.022
K81.9 Cholecystitis, unspecified	0.000	0.979	0.021
K83 Other diseases of biliary tract	0.000	0.980	0.020
R07.0 Pain in throat	0.000	0.982	0.018
B00.1 Herpesviral vesicular dermatitis	0.000	0.983	0.017
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.000	0.983	0.017
B00.4 Herpesviral encephalitis	0.000	0.984	0.016
B00.7 Disseminated herpesviral disease	0.000	0.984	0.016
B00.0 Eczema herpeticum	0.000	0.984	0.016
K83.5 Biliary cyst	0.000	0.984	0.016
B00.5 Herpesviral ocular disease	0.000	0.984	0.016
K83.0 Cholangitis	0.000	0.985	0.015
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.985	0.015
K83.4 Spasm of sphincter of Oddi	0.000	0.985	0.014
K83.2 Perforation of bile duct	0.000	0.985	0.014
B00.3 Herpesviral meningitis	0.000	0.986	0.014
B00.8 Other forms of herpesviral infection	0.000	0.986	0.014
M13.9 Arthritis, unspecified	0.000	0.987	0.013
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.987	0.013
K83.3 Fistula of bile duct	0.000	0.988	0.012
M13.90 Arthritis, unspecified (Multiple sites)	0.000	0.988	0.012
M13.92 Arthritis, unspecified (Upper arm)	0.000	0.989	0.011
G51.0 Bell's palsy	0.011	0.989	0.000
K83.9 Disease of biliary tract, unspecified	0.000	0.990	0.010
I50.9 Heart failure, unspecified	0.010	0.990	0.000
M13.98 Arthritis, unspecified (Other)	0.000	0.990	0.010
D72.8 Other specified disorders of white blood cells	0.009	0.991	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.991	0.009
B00.9 Herpesviral infection, unspecified	0.001	0.991	0.008
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.009	0.991	0.000
M23.8 Other internal derangements of knee	0.000	0.992	0.008
D86.0 Sarcoidosis of lung	0.000	0.992	0.008
D86 Sarcoidosis	0.000	0.992	0.008
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.992	0.008
M13.93 Arthritis, unspecified (Forearm)	0.000	0.992	0.008
I60 Subarachnoid haemorrhage	0.008	0.992	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.992	0.008
I60.9 Subarachnoid haemorrhage, unspecified	0.007	0.993	0.000
I82.8 Embolism and thrombosis of other specified veins	0.000	0.993	0.007
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.007	0.993	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.007	0.993	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.993	0.007
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.007	0.993	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.993	0.006
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.006	0.994	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.994	0.006
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.994	0.006
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.994	0.006
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.994	0.006
D86.3 Sarcoidosis of skin	0.000	0.994	0.006
M13.94 Arthritis, unspecified (Hand)	0.000	0.994	0.006
D55-D59 Haemolytic anaemias	0.000	0.994	0.006
M13.97 Arthritis, unspecified (Ankle and foot)	0.000	0.994	0.006
D86.9 Sarcoidosis, unspecified	0.000	0.994	0.006
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.994	0.006
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.994	0.006
I60.5 Subarachnoid haemorrhage from vertebral artery	0.006	0.994	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.994	0.006
D81 Combined immunodeficiencies	0.000	0.994	0.006
G51 Facial nerve disorders	0.006	0.994	0.000
D84 Other immunodeficiencies	0.000	0.994	0.006
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.000	0.994	0.006
D83 Common variable immunodeficiency	0.000	0.994	0.005
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.005	0.994	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.994	0.005
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.995	0.005
F30.0 Hypomania	0.000	0.995	0.005
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.995	0.005
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.995	0.005
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.995	0.005
M13 Other arthritis	0.000	0.995	0.005
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.995	0.005
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.995	0.005
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.995	0.005
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.995	0.005
D84.1 Defects in the complement system	0.000	0.995	0.005
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.995	0.005
R79.9 Abnormal finding of blood chemistry, unspecified	0.005	0.995	0.000
D57 Sickle-cell disorders	0.000	0.995	0.005
F30.2 Mania with psychotic symptoms	0.000	0.995	0.005
G51.9 Disorder of facial nerve, unspecified	0.005	0.995	0.000
K83.8 Other specified diseases of biliary tract	0.000	0.995	0.005
D58 Other hereditary haemolytic anaemias	0.000	0.995	0.005
K83.1 Obstruction of bile duct	0.000	0.995	0.005
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.995	0.005
D86.1 Sarcoidosis of lymph nodes	0.000	0.995	0.005
I60.8 Other subarachnoid haemorrhage	0.005	0.995	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.995	0.005
S82.20 Fracture of shaft of tibia (closed)	0.000	0.995	0.005
M79.64 Pain in limb (Hand)	0.000	0.995	0.005
D72 Other disorders of white blood cells	0.004	0.995	0.000
G51.8 Other disorders of facial nerve	0.004	0.995	0.000
D55 Anaemia due to enzyme disorders	0.000	0.995	0.004
F30 Manic episode	0.000	0.995	0.005
D58.2 Other haemoglobinopathies	0.000	0.996	0.004
D81.9 Combined immunodeficiency, unspecified	0.000	0.996	0.004
D81.8 Other combined immunodeficiencies	0.000	0.996	0.004
D81.7 Major histocompatibility complex class II deficiency	0.000	0.996	0.004
D81.6 Major histocompatibility complex class I deficiency	0.000	0.996	0.004
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.996	0.004
D81.4 Nezelof's syndrome	0.000	0.996	0.004
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.996	0.004
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.996	0.004
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.996	0.004
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.996	0.004
D57.1 Sickle-cell anaemia without crisis	0.000	0.996	0.004
G51.4 Facial myokymia	0.004	0.996	0.000
G51.2 Melkersson's syndrome	0.004	0.996	0.000
G51.1 Geniculate ganglionitis	0.004	0.996	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.996	0.004
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.996	0.004
I82 Other venous embolism and thrombosis	0.000	0.996	0.004
D83.8 Other common variable immunodeficiencies	0.000	0.996	0.004
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.996	0.004
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.996	0.004
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.996	0.004
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.996	0.004
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.996	0.004
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.996	0.004
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.996	0.004
D82.2 Immunodeficiency with short-limbed stature	0.000	0.996	0.004
D82.0 Wiskott-Aldrich syndrome	0.000	0.996	0.004
Z89.5 Acquired absence of leg at or below knee	0.004	0.996	0.000
K81.0 Acute cholecystitis	0.000	0.996	0.004
G51.3 Clonic hemifacial spasm	0.004	0.996	0.000
X59.2 School, other institution and public administrative area	0.004	0.996	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.004	0.996	0.000
D83.9 Common variable immunodeficiency, unspecified	0.000	0.996	0.004
D59 Acquired haemolytic anaemia	0.000	0.996	0.004
A63.0 Anogenital (venereal) warts	0.000	0.996	0.004
D82.1 Di George's syndrome	0.000	0.996	0.004
M13.1 Monoarthritis, not elsewhere classified	0.000	0.996	0.004
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.996	0.004
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.996	0.004
M13.8 Other specified arthritis	0.000	0.996	0.004
D57.8 Other sickle-cell disorders	0.000	0.996	0.004
D57.3 Sickle-cell trait	0.000	0.996	0.004
D57.2 Double heterozygous sickling disorders	0.000	0.996	0.004
D57.0 Sickle-cell anaemia with crisis	0.000	0.996	0.004
D84.9 Immunodeficiency, unspecified	0.000	0.996	0.004
D58.8 Other specified hereditary haemolytic anaemias	0.000	0.996	0.004
D58.1 Hereditary elliptocytosis	0.000	0.996	0.004
F30.1 Mania without psychotic symptoms	0.000	0.996	0.004
I82.2 Embolism and thrombosis of vena cava	0.000	0.996	0.004
D56 Thalassaemia	0.000	0.996	0.003
D58.0 Hereditary spherocytosis	0.000	0.996	0.003
D72.1 Eosinophilia	0.003	0.996	0.000
D84.8 Other specified immunodeficiencies	0.000	0.996	0.003
M13.0 Polyarthritis, unspecified	0.000	0.996	0.004
D72.9 Disorder of white blood cells, unspecified	0.003	0.996	0.000
D72.0 Genetic anomalies of leukocytes	0.003	0.996	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.996	0.003
D55.8 Other anaemias due to enzyme disorders	0.000	0.996	0.003
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.996	0.003
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.996	0.003
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.996	0.003
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.996	0.003
F30.8 Other manic episodes	0.000	0.996	0.003
K74.6 Other and unspecified cirrhosis of liver	0.000	0.996	0.004
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.997	0.003
I82.0 Budd-Chiari syndrome	0.000	0.997	0.003
I82.3 Embolism and thrombosis of renal vein	0.000	0.997	0.003
Z29.2 Other prophylactic chemotherapy	0.003	0.997	0.000
I82.1 Thrombophlebitis migrans	0.000	0.997	0.003
Z48.9 Surgical follow-up care, unspecified	0.003	0.997	0.000
K81.1 Chronic cholecystitis	0.000	0.997	0.003
D59.1 Other autoimmune haemolytic anaemias	0.000	0.997	0.003
M13.86 Other specified arthritis (Lower leg)	0.000	0.997	0.003
Y45.1 Salicylates	0.003	0.997	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.997	0.003
D59.8 Other acquired haemolytic anaemias	0.000	0.997	0.003
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.997	0.003
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.997	0.003
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.997	0.003
D59.3 Haemolytic-uraemic syndrome	0.000	0.997	0.003
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.997	0.003
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.003	0.997	0.000
F30.9 Manic episode, unspecified	0.000	0.997	0.003
M13.19 Monoarthritis, not elsewhere classified (Site unspecified)	0.000	0.997	0.003
M13.18 Monoarthritis, not elsewhere classified (Other)	0.000	0.997	0.003
M13.17 Monoarthritis, not elsewhere classified (Ankle and foot)	0.000	0.997	0.003
M13.15 Monoarthritis, not elsewhere classified (Pelvic region and thigh)	0.000	0.997	0.003
M13.14 Monoarthritis, not elsewhere classified (Hand)	0.000	0.997	0.003
M13.13 Monoarthritis, not elsewhere classified (Forearm)	0.000	0.997	0.003
M13.12 Monoarthritis, not elsewhere classified (Upper arm)	0.000	0.997	0.003
M13.11 Monoarthritis, not elsewhere classified (Shoulder region)	0.000	0.997	0.003
M13.10 Monoarthritis, not elsewhere classified (Multiple sites)	0.000	0.997	0.003
M13.89 Other specified arthritis (Site unspecified)	0.000	0.997	0.003
D89.3 Immune reconstitution syndrome	0.000	0.997	0.003
D60-D64 Aplastic and other anaemias	0.000	0.997	0.003
M13.88 Other specified arthritis (Other)	0.000	0.997	0.003
M13.85 Other specified arthritis (Pelvic region and thigh)	0.000	0.997	0.003
M13.84 Other specified arthritis (Hand)	0.000	0.997	0.003
M13.83 Other specified arthritis (Forearm)	0.000	0.997	0.003
M13.82 Other specified arthritis (Upper arm)	0.000	0.997	0.003
M13.81 Other specified arthritis (Shoulder region)	0.000	0.997	0.003
N80.8 Other endometriosis	0.000	0.997	0.003
M13.16 Monoarthritis, not elsewhere classified (Lower leg)	0.000	0.997	0.003
M13.87 Other specified arthritis (Ankle and foot)	0.000	0.997	0.003
E14.3 With ophthalmic complications	0.000	0.997	0.003
D62 Acute posthaemorrhagic anaemia	0.000	0.997	0.003
D56.9 Thalassaemia, unspecified	0.000	0.997	0.003
D56.8 Other thalassaemias	0.000	0.997	0.003
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.000	0.997	0.003
D56.2 Delta-beta thalassaemia	0.000	0.997	0.003
D56.0 Alpha thalassaemia	0.000	0.997	0.003
H40.2 Primary angle-closure glaucoma	0.003	0.997	0.000
M13.06 Polyarthritis, unspecified (Lower leg)	0.000	0.997	0.003
M13.04 Polyarthritis, unspecified (Hand)	0.000	0.997	0.003
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.997	0.003
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.997	0.003
M13.08 Polyarthritis, unspecified (Other)	0.000	0.997	0.003
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.000	0.997	0.003
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
M13.03 Polyarthritis, unspecified (Forearm)	0.000	0.997	0.003
M13.02 Polyarthritis, unspecified (Upper arm)	0.000	0.997	0.003
M13.01 Polyarthritis, unspecified (Shoulder region)	0.000	0.997	0.003
X59 Exposure to unspecified factor	0.003	0.997	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.997	0.003
O47.0 False labour before 37 completed weeks of gestation	0.003	0.997	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.000	0.997	0.003
O47.1 False labour at or after 37 completed weeks of gestation	0.003	0.997	0.000
M13.80 Other specified arthritis (Multiple sites)	0.000	0.997	0.003
D89.1 Cryoglobulinaemia	0.000	0.997	0.003
D56.1 Beta thalassaemia	0.000	0.997	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.997	0.003
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.003	0.997	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.997	0.002
X59.6 Industrial and construction area	0.003	0.997	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.997	0.002
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
K05.3 Chronic periodontitis	0.000	0.998	0.002
Z89.6 Acquired absence of leg above knee	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.998	0.002
D61.9 Aplastic anaemia, unspecified	0.002	0.998	0.000
X59.3 Sports and athletics area	0.002	0.998	0.000
D56.3 Thalassaemia trait	0.000	0.998	0.002
I50 Heart failure	0.002	0.998	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.001	0.998	0.001
D60.9 Acquired pure red cell aplasia, unspecified	0.000	0.998	0.002
X59.9 Unspecified place	0.002	0.998	0.000
X59.8 Other specified place	0.002	0.998	0.000
X59.0 Home	0.002	0.998	0.000
X59.7 Farm	0.002	0.998	0.000
X59.5 Trade and service area	0.002	0.998	0.000
X59.1 Residential institution	0.002	0.998	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.000	0.998	0.002
Z85.9 Personal history of malignant neoplasm, unspecified	0.002	0.998	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
Z89 Acquired absence of limb	0.002	0.998	0.000
X59.4 Street and highway	0.002	0.998	0.000
D61 Other aplastic anaemias	0.001	0.998	0.001
M13.09 Polyarthritis, unspecified (Site unspecified)	0.000	0.998	0.002
C78.4 Secondary malignant neoplasm of small intestine	0.002	0.998	0.000
J98.1 Pulmonary collapse	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.000	0.998	0.002
T02.4 Fractures involving multiple regions of both upper limbs	0.002	0.998	0.000
D60.8 Other acquired pure red cell aplasias	0.000	0.998	0.002
D60.1 Transient acquired pure red cell aplasia	0.000	0.998	0.002
D60.0 Chronic acquired pure red cell aplasia	0.000	0.998	0.002
N20.2 Calculus of kidney with calculus of ureter	0.000	0.998	0.002
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.002	0.998	0.000
M75.2 Bicipital tendinitis	0.000	0.998	0.002
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.998	0.002
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.002	0.998	0.000
I84.1 Internal haemorrhoids with other complications	0.002	0.998	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.002	0.998	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.000	0.998	0.002
S62.51 Fracture of thumb (open)	0.000	0.998	0.002
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.998	0.002
N97.9 Female infertility, unspecified	0.000	0.998	0.002
X59.09 Exposure to unspecified factor causing fracture; Unspecified place;	0.002	0.998	0.000
X59.88 Exposure to unspecified factor; Other specified places ;While engaged in other specified activities	0.002	0.998	0.000
X59.99 Exposure to unspecified factor causing other and unspecified injury, Unspecified place	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.998	0.002
Z89.4 Acquired absence of foot and ankle	0.002	0.998	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.002	0.998	0.000
Z89.1 Acquired absence of hand and wrist	0.002	0.998	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.998	0.002
D61.8 Other specified aplastic anaemias	0.001	0.998	0.001
D61.3 Idiopathic aplastic anaemia	0.001	0.998	0.001
D61.2 Aplastic anaemia due to other external agents	0.001	0.998	0.001
Z48.8 Other specified surgical follow-up care	0.002	0.998	0.000
T02.41 Fractures involving multiple regions of both upper limbs (open)	0.002	0.998	0.000
D61.0 Constitutional aplastic anaemia	0.001	0.998	0.001
X78.0 Home	0.002	0.998	0.000
O04.4 Incomplete, without complication	0.002	0.998	0.000
O47 False labour	0.002	0.998	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.998	0.002
N30.1 Interstitial cystitis (chronic)	0.000	0.998	0.002
D61.1 Drug-induced aplastic anaemia	0.001	0.998	0.001
T46.1 Calcium-channel blockers	0.002	0.998	0.000
I61 Intracerebral haemorrhage	0.000	0.998	0.002
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.998	0.002
O47.9 False labour, unspecified	0.000	0.998	0.002
A08.4 Viral intestinal infection, unspecified	0.000	0.998	0.002
A63.8 Other specified predominantly sexually transmitted diseases	0.000	0.998	0.002
D50-D53 Nutritional anaemias	0.000	0.998	0.002
I27.9 Pulmonary heart disease, unspecified	0.002	0.998	0.000
C90.0 Multiple myeloma	0.002	0.998	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.998	0.002
N80.0 Endometriosis of uterus	0.000	0.998	0.002
I50.0 Congestive heart failure	0.002	0.998	0.000
Z89.9 Acquired absence of limb, unspecified	0.002	0.998	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.998	0.002
Z97.4 Presence of external hearing-aid	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.002	0.998	0.000
N13.8 Other obstructive and reflux uropathy	0.002	0.998	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.998	0.002
A46 Erysipelas	0.000	0.998	0.002
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.998	0.002
I87.8 Other specified disorders of veins	0.002	0.998	0.000
O30.0 Twin pregnancy	0.000	0.998	0.002
E87.0 Hyperosmolality and hypernatraemia	0.000	0.998	0.002
T51.9 Alcohol, unspecified	0.002	0.998	0.000
M17.1 Other primary gonarthrosis	0.000	0.998	0.002
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.001	0.998	0.000
Z89.2 Acquired absence of upper limb above wrist	0.001	0.998	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.998	0.001
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.998	0.002
M07.3 Other psoriatic arthropathies	0.000	0.998	0.002
M17.3 Other posttraumatic gonarthrosis	0.000	0.998	0.002
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.998	0.002
S02.10 Fracture of base of skull (closed)	0.000	0.998	0.001
B18.1 Chronic viral hepatitis B without delta-agent	0.001	0.998	0.000
E05.8 Other thyrotoxicosis	0.000	0.998	0.001
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.998	0.001
R25.8 Other and unspecified abnormal involuntary movements	0.001	0.999	0.000
Z97.0 Presence of artificial eye	0.001	0.999	0.000
D52 Folate deficiency anaemia	0.000	0.999	0.001
B19.9 Unspecified viral hepatitis without coma	0.001	0.999	0.000
S60.8 Other superficial injuries of wrist and hand	0.000	0.999	0.001
Z84.8 Family history of other specified conditions	0.001	0.999	0.000
Z48 Other surgical follow-up care	0.001	0.999	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.999	0.001
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.999	0.001
O34.7 Maternal care for abnormality of vulva and perineum	0.000	0.999	0.001
Z00.6 Examination for normal comparison and control in clinical research programme	0.000	0.999	0.001
T02 Fractures involving multiple body regions	0.001	0.999	0.000
H70.9 Mastoiditis, unspecified	0.000	0.999	0.001
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.999	0.001
S82.2 Fracture of shaft of tibia	0.000	0.999	0.001
Z97.5 Presence of (intra-uterine) contraceptive device	0.001	0.999	0.000
N18.5 Chronic kidney disease, stage 5	0.000	0.999	0.001
Z00.5 Examination of potential donor of organ and tissue	0.000	0.999	0.001
D53 Other nutritional anaemias	0.000	0.999	0.001
M13.99 Arthritis, unspecified (Site unspecified)	0.000	0.999	0.001
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.999	0.001
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.999	0.001
L98.0 Pyogenic granuloma	0.001	0.999	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.999	0.001
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.999	0.001
E05.5 Thyroid crisis or storm	0.000	0.999	0.001
E05.4 Thyrotoxicosis factitia	0.000	0.999	0.001
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.999	0.001
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.999	0.001
Y45.2 Propionic acid derivatives	0.001	0.999	0.000
Z93.1 Gastrostomy status	0.000	0.999	0.001
C78.7 Secondary malignant neoplasm of liver	0.001	0.999	0.000
I27.2 Other secondary pulmonary hypertension	0.001	0.999	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.001	0.999	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.000	0.999	0.001
D25.1 Intramural leiomyoma of uterus	0.000	0.999	0.001
I31.3 Pericardial effusion (noninflammatory)	0.001	0.999	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.999	0.001
B18.2 Chronic viral hepatitis C	0.001	0.999	0.000
D52.8 Other folate deficiency anaemias	0.000	0.999	0.001
D52.1 Drug-induced folate deficiency anaemia	0.000	0.999	0.001
D52.0 Dietary folate deficiency anaemia	0.000	0.999	0.001
T02.8 Fractures involving other combinations of body regions	0.001	0.999	0.000
Z97.1 Presence of artificial limb (complete)(partial)	0.001	0.999	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.999	0.001
B15.9 Hepatitis A without hepatic coma	0.001	0.999	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.001	0.999	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.999	0.001
T02.9 Multiple fractures, unspecified	0.001	0.999	0.000
T02.7 Fractures involving thorax with lower back and pelvis with limb(s)	0.001	0.999	0.000
T02.6 Fractures involving multiple regions of upper limb(s) with lower limb(s)	0.001	0.999	0.000
T02.3 Fractures involving multiple regions of one lower limb	0.001	0.999	0.000
T02.2 Fractures involving multiple regions of one upper limb	0.001	0.999	0.000
T02.1 Fractures involving thorax with lower back and pelvis	0.001	0.999	0.000
T02.0 Fractures involving head with neck	0.001	0.999	0.000
F33 Recurrent depressive disorder	0.000	0.999	0.001
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.001	0.999	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.999	0.001
L25.9 Unspecified contact dermatitis, unspecified cause	0.000	0.999	0.001
X50.4 Street and highway	0.001	0.999	0.000
B18 Chronic viral hepatitis	0.001	0.999	0.000
D53.8 Other specified nutritional anaemias	0.000	0.999	0.001
D53.2 Scorbutic anaemia	0.000	0.999	0.001
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.999	0.001
D53.0 Protein deficiency anaemia	0.000	0.999	0.001
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.999	0.001
T02.5 Fractures involving multiple regions of both lower limbs	0.001	0.999	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.999	0.000
Z46.7 Fitting and adjustment of orthopaedic device	0.000	0.999	0.001
T02.80 Fractures involving other combinations of body regions (closed)	0.001	0.999	0.000
D63.0 Anaemia in neoplastic disease	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations