TreeWAS – Variant ID: rs4886585

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I70-I79 Diseases of arteries, arterioles and capillaries	1.000	0.000	0.000
I71 Aortic aneurysm and dissection	1.000	0.000	0.000
I20.9 Angina pectoris, unspecified	0.000	0.002	0.998
I72 Other aneurysm	0.997	0.003	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.997	0.003	0.000
I20 Angina pectoris	0.000	0.007	0.993
J43.9 Emphysema, unspecified	0.993	0.007	0.000
I25 Chronic ischaemic heart disease	0.000	0.011	0.989
I20-I25 Ischaemic heart diseases	0.000	0.011	0.989
I74 Arterial embolism and thrombosis	0.988	0.012	0.000
I72.0 Aneurysm of carotid artery	0.968	0.032	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.052	0.948
I72.8 Aneurysm of other specified arteries	0.943	0.057	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.936	0.064	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.930	0.070	0.000
I72.4 Aneurysm of artery of lower extremity	0.920	0.080	0.000
I24 Other acute ischaemic heart diseases	0.000	0.087	0.913
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.897	0.103	0.000
I77 Other disorders of arteries and arterioles	0.889	0.111	0.000
I74.5 Embolism and thrombosis of iliac artery	0.886	0.114	0.000
I20.1 Angina pectoris with documented spasm	0.000	0.127	0.873
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.873	0.127	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.871	0.129	0.000
I78 Diseases of capillaries	0.865	0.135	0.000
I20.8 Other forms of angina pectoris	0.000	0.144	0.856
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.147	0.853
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.847	0.153	0.000
I71.0 Dissection of aorta [any part]	0.830	0.170	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.823	0.177	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.192	0.808
I70 Atherosclerosis	0.801	0.199	0.000
I73 Other peripheral vascular diseases	0.796	0.204	0.000
I77.8 Other specified disorders of arteries and arterioles	0.795	0.205	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.230	0.770
I72.2 Aneurysm of renal artery	0.764	0.236	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.749	0.251	0.000
I72.9 Aneurysm of unspecified site	0.748	0.252	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.735	0.265	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.731	0.269	0.000
I77.2 Rupture of artery	0.729	0.271	0.000
I24.1 Dressler's syndrome	0.000	0.282	0.718
I71.8 Aortic aneurysm of unspecified site, ruptured	0.717	0.283	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.717	0.283	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.715	0.285	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.715	0.285	0.000
I70.8 Atherosclerosis of other arteries	0.702	0.298	0.000
I78.8 Other diseases of capillaries	0.672	0.328	0.000
J43 Emphysema	0.671	0.329	0.000
I73.9 Peripheral vascular disease, unspecified	0.671	0.329	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.671	0.329	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.665	0.335	0.000
I77.6 Arteritis, unspecified	0.657	0.343	0.000
I23 Certain current complications following acute myocardial infarction	0.000	0.349	0.651
I72.3 Aneurysm of iliac artery	0.647	0.352	0.000
I25.6 Silent myocardial ischaemia	0.000	0.354	0.645
I77.5 Necrosis of artery	0.638	0.362	0.000
I77.4 Coeliac artery compression syndrome	0.638	0.362	0.000
I77.3 Arterial fibromuscular dysplasia	0.638	0.362	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.631	0.369	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.622	0.377	0.000
I78.9 Disease of capillaries, unspecified	0.620	0.380	0.000
I70.9 Generalised and unspecified atherosclerosis	0.618	0.382	0.000
I73.8 Other specified peripheral vascular diseases	0.613	0.387	0.000
I72.1 Aneurysm of artery of upper extremity	0.611	0.389	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.606	0.393	0.000
J43.2 Centrilobular emphysema	0.602	0.398	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.593	0.407	0.000
I77.0 Arteriovenous fistula, acquired	0.592	0.408	0.000
I70.1 Atherosclerosis of renal artery	0.585	0.414	0.000
I22 Subsequent myocardial infarction	0.000	0.436	0.564
I74.8 Embolism and thrombosis of other arteries	0.546	0.453	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.529	0.470	0.000
I25.3 Aneurysm of heart	0.000	0.478	0.522
I25.4 Coronary artery aneurysm	0.000	0.489	0.511
I70.81 Atherosclerosis of other arteries (with gangrene)	0.503	0.497	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.504	0.496
J43.8 Other emphysema	0.489	0.511	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.487	0.512	0.000
J43.1 Panlobular emphysema	0.481	0.519	0.000
J43.0 MacLeod's syndrome	0.481	0.519	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.533	0.467
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.533	0.467
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.533	0.467
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.533	0.467
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.533	0.467
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.533	0.467
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.533	0.467
I22.8 Subsequent myocardial infarction of other sites	0.000	0.552	0.448
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.443	0.557	0.000
I70.0 Atherosclerosis of aorta	0.443	0.557	0.000
I79.1 Aortitis in diseases classified elsewhere	0.435	0.565	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.435	0.565	0.000
I25.5 Ischaemic cardiomyopathy	0.000	0.567	0.433
I70.10 Atherosclerosis of renal artery (without gangrene)	0.431	0.568	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.420	0.580	0.000
I23.8 Other current complications following acute myocardial infarction	0.000	0.591	0.409
I77.1 Stricture of artery	0.407	0.593	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.392	0.608	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.381	0.619	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.376	0.624	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.339	0.660	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.318	0.682	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.786	0.214
I73.0 Raynaud's syndrome	0.210	0.790	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.187	0.813	0.001
I78.1 Naevus, nonneoplastic	0.156	0.844	0.000
I24.8 Other forms of acute ischaemic heart disease	0.000	0.848	0.152
C34.9 Bronchus or lung, unspecified	0.148	0.852	0.000
C34 Malignant neoplasm of bronchus and lung	0.137	0.863	0.000
Z72.1 Alcohol use	0.133	0.867	0.000
I21 Acute myocardial infarction	0.000	0.874	0.126
C34.1 Upper lobe, bronchus or lung	0.121	0.879	0.000
I25.2 Old myocardial infarction	0.000	0.879	0.121
I22.1 Subsequent myocardial infarction of inferior wall	0.001	0.880	0.119
C34.3 Lower lobe, bronchus or lung	0.118	0.882	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.884	0.116
C34.8 Overlapping lesion of bronchus and lung	0.112	0.888	0.000
C34.2 Middle lobe, bronchus or lung	0.112	0.888	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.895	0.105
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.094	0.906	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.910	0.090
C32 Malignant neoplasm of larynx	0.088	0.912	0.000
C32.9 Larynx, unspecified	0.081	0.919	0.000
C33 Malignant neoplasm of trachea	0.076	0.923	0.000
I20.0 Unstable angina	0.000	0.927	0.073
I21.4 Acute subendocardial myocardial infarction	0.000	0.927	0.073
C38 Malignant neoplasm of heart, mediastinum and pleura	0.071	0.929	0.000
C32.1 Supraglottis	0.071	0.929	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.930	0.070
C32.0 Glottis	0.069	0.931	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.068	0.932	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.066	0.934	0.000
C32.8 Overlapping lesion of larynx	0.063	0.936	0.000
C32.3 Laryngeal cartilage	0.063	0.936	0.000
C32.2 Subglottis	0.063	0.936	0.000
C31 Malignant neoplasm of accessory sinuses	0.061	0.939	0.000
C38.3 Mediastinum, part unspecified	0.058	0.942	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.943	0.057
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.051	0.949	0.000
C38.2 Posterior mediastinum	0.051	0.949	0.000
C38.1 Anterior mediastinum	0.051	0.949	0.000
C38.0 Heart	0.051	0.949	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.950	0.050
C39.9 Ill-defined sites within the respiratory system	0.049	0.951	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.049	0.951	0.000
C39.0 Upper respiratory tract, part unspecified	0.049	0.951	0.000
C37 Malignant neoplasm of thymus	0.047	0.952	0.000
C38.4 Pleura	0.047	0.952	0.000
C30.1 Middle ear	0.047	0.953	0.000
C30.0 Nasal cavity	0.045	0.954	0.000
C31.9 Accessory sinus, unspecified	0.044	0.956	0.000
C31.8 Overlapping lesion of accessory sinuses	0.044	0.956	0.000
C31.3 Sphenoidal sinus	0.044	0.956	0.000
C31.2 Frontal sinus	0.044	0.956	0.000
C31.1 Ethmoidal sinus	0.044	0.956	0.000
C34.0 Main bronchus	0.039	0.960	0.000
C31.0 Maxillary sinus	0.037	0.962	0.000
Z72 Problems related to lifestyle	0.033	0.967	0.000
Z72.2 Drug use	0.027	0.973	0.000
Z72.9 Problem related to lifestyle, unspecified	0.026	0.974	0.000
S62.61 Fracture of other finger (open)	0.024	0.976	0.000
Z72.6 Gambling and betting	0.024	0.976	0.000
Z72.5 High-risk sexual behaviour	0.024	0.976	0.000
Z72.3 Lack of physical exercise	0.024	0.976	0.000
Z72.4 Inappropriate diet and eating habits	0.022	0.978	0.000
Z72.8 Other problems related to lifestyle	0.021	0.979	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.983	0.017
J40-J47 Chronic lower respiratory diseases	0.016	0.984	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.985	0.015
J44 Other chronic obstructive pulmonary disease	0.015	0.985	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.015	0.985	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.013	0.987	0.000
J41 Simple and mucopurulent chronic bronchitis	0.012	0.988	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.010	0.990	0.000
J41.0 Simple chronic bronchitis	0.010	0.990	0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.009	0.991	0.000
J41.1 Mucopurulent chronic bronchitis	0.009	0.991	0.000
H35.3 Degeneration of macula and posterior pole	0.009	0.991	0.000
C77.5 Intrapelvic lymph nodes	0.009	0.991	0.000
Chapter IX Diseases of the circulatory system	0.008	0.992	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.008	0.992	0.000
I87.8 Other specified disorders of veins	0.000	0.993	0.007
S62.6 Fracture of other finger	0.007	0.993	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.007	0.993	0.000
I00-I02 Acute rheumatic fever	0.007	0.993	0.000
J45 Asthma	0.007	0.993	0.000
Z36 Antenatal screening	0.006	0.994	0.000
J46 Status asthmaticus	0.006	0.994	0.000
Z36.9 Antenatal screening, unspecified	0.006	0.994	0.000
I00 Rheumatic fever without mention of heart involvement	0.006	0.994	0.000
J45.1 Nonallergic asthma	0.006	0.994	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.006	0.994	0.000
Z33 Pregnant state, incidental	0.006	0.994	0.000
D25.0 Submucous leiomyoma of uterus	0.000	0.994	0.006
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.006	0.994	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.005	0.995	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.005	0.995	0.000
I05-I09 Chronic rheumatic heart diseases	0.005	0.995	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.005	0.995	0.000
J45.8 Mixed asthma	0.005	0.995	0.000
I06 Rheumatic aortic valve diseases	0.005	0.995	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.005	0.995	0.000
I02 Rheumatic chorea	0.005	0.995	0.000
I01 Rheumatic fever with heart involvement	0.005	0.995	0.000
J42 Unspecified chronic bronchitis	0.005	0.995	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.005	0.995	0.000
Z36.5 Antenatal screening for isoimmunisation	0.005	0.995	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.005	0.995	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
I99 Other and unspecified disorders of circulatory system	0.005	0.995	0.000
I06.0 Rheumatic aortic stenosis	0.005	0.995	0.000
I06.1 Rheumatic aortic insufficiency	0.005	0.995	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.004	0.995	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.004	0.995	0.000
I87 Other disorders of veins	0.000	0.995	0.005
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.995	0.004
J18.1 Lobar pneumonia, unspecified	0.004	0.996	0.000
Z72.0 Tobacco use	0.004	0.996	0.000
I05 Rheumatic mitral valve diseases	0.004	0.996	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.004	0.996	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
I98.0 Cardiovascular syphilis	0.004	0.996	0.000
I27 Other pulmonary heart diseases	0.004	0.996	0.000
Z75 Problems related to medical facilities and other health care	0.004	0.996	0.000
I09 Other rheumatic heart diseases	0.004	0.996	0.000
I06.8 Other rheumatic aortic valve diseases	0.004	0.996	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.004	0.996	0.000
I28 Other diseases of pulmonary vessels	0.004	0.996	0.000
M77.57 Other enthesopathy of foot-Ankle/Foot	0.000	0.996	0.004
I27.9 Pulmonary heart disease, unspecified	0.004	0.996	0.000
I07 Rheumatic tricuspid valve diseases	0.004	0.996	0.000
Z75.4 Unavailability and inaccessibility of other helping agencies	0.004	0.996	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.004	0.996	0.000
I01.8 Other acute rheumatic heart disease	0.004	0.996	0.000
I01.2 Acute rheumatic myocarditis	0.004	0.996	0.000
I01.1 Acute rheumatic endocarditis	0.004	0.996	0.000
I01.0 Acute rheumatic pericarditis	0.004	0.996	0.000
I02.9 Rheumatic chorea without heart involvement	0.004	0.996	0.000
I02.0 Rheumatic chorea with heart involvement	0.004	0.996	0.000
Z74 Problems related to care-provider dependency	0.004	0.996	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.004	0.996	0.000
C67.1 Dome of bladder	0.004	0.996	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.004	0.996	0.000
I05.0 Mitral stenosis	0.004	0.996	0.000
I27.8 Other specified pulmonary heart diseases	0.004	0.996	0.000
K56.1 Intussusception	0.000	0.996	0.004
Z75.8 Other problems related to medical facilities and other health care	0.004	0.996	0.000
Z70 Counselling related to sexual attitude, behaviour and orientation	0.004	0.996	0.000
J40 Bronchitis, not specified as acute or chronic	0.004	0.996	0.000
Z75.2 Other waiting period for investigation and treatment	0.004	0.996	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.004	0.996	0.000
I87.0 Postphlebitic syndrome	0.000	0.996	0.003
K62.8 Other specified diseases of anus and rectum	0.004	0.996	0.000
Z75.0 Medical services not available in home	0.003	0.996	0.000
Z76 Persons encountering health services in other circumstances	0.003	0.996	0.000
D38.1 Trachea, bronchus and lung	0.003	0.997	0.000
I05.2 Mitral stenosis with insufficiency	0.003	0.997	0.000
Z74.8 Other problems related to care-provider dependency	0.003	0.997	0.000
I87.1 Compression of vein	0.000	0.997	0.003
I27.0 Primary pulmonary hypertension	0.003	0.997	0.000
J18.0 Bronchopneumonia, unspecified	0.003	0.997	0.000
I05.8 Other mitral valve diseases	0.003	0.997	0.000
Z74.1 Need for assistance with personal care	0.003	0.997	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.003	0.997	0.000
I27.1 Kyphoscoliotic heart disease	0.003	0.997	0.000
Z75.5 Holiday relief care	0.003	0.997	0.000
Z75.9 Unspecified problem related to medical facilities and other health care	0.003	0.997	0.000
I05.1 Rheumatic mitral insufficiency	0.003	0.997	0.000
I87.9 Disorder of vein, unspecified	0.000	0.997	0.003
I09.8 Other specified rheumatic heart diseases	0.003	0.997	0.000
I09.2 Chronic rheumatic pericarditis	0.003	0.997	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.003	0.997	0.000
I09.0 Rheumatic myocarditis	0.003	0.997	0.000
S62.60 Fracture of other finger (closed)	0.003	0.997	0.000
I28.8 Other specified diseases of pulmonary vessels	0.003	0.997	0.000
I28.1 Aneurysm of pulmonary artery	0.003	0.997	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.003	0.997	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.997	0.003
I09.9 Rheumatic heart disease, unspecified	0.003	0.997	0.000
N81.9 Female genital prolapse, unspecified	0.000	0.997	0.003
D75.8 Other specified diseases of blood and blood-forming organs	0.003	0.997	0.000
I07.9 Tricuspid valve disease, unspecified	0.003	0.997	0.000
I07.8 Other tricuspid valve diseases	0.003	0.997	0.000
I07.2 Tricuspid stenosis with insufficiency	0.003	0.997	0.000
I07.0 Tricuspid stenosis	0.003	0.997	0.000
Z76.8 Persons encountering health services in other specified circumstances	0.003	0.997	0.000
Z74.3 Need for continuous supervision	0.003	0.997	0.000
L73.9 Follicular disorder, unspecified	0.000	0.997	0.003
I05.9 Mitral valve disease, unspecified	0.003	0.997	0.000
Z70.9 Sex counselling, unspecified	0.003	0.997	0.000
Z70.8 Other sex counselling	0.003	0.997	0.000
Z70.3 Counselling related to combined concerns regarding sexual attitude, behaviour and orientation	0.003	0.997	0.000
Z70.2 Counselling related to sexual behaviour and orientation of third party	0.003	0.997	0.000
Z70.0 Counselling related to sexual attitude	0.003	0.997	0.000
I07.1 Tricuspid insufficiency	0.003	0.997	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
Z76.5 Malingerer [conscious situation]	0.003	0.997	0.000
Z76.4 Other boarder in health-care facility	0.003	0.997	0.000
Z76.2 Health supervision and care of other healthy infant and child	0.003	0.997	0.000
Z76.1 Health supervision and care of foundling	0.003	0.997	0.000
Z76.0 Issue of repeat prescription	0.003	0.997	0.000
J18 Pneumonia, organism unspecified	0.003	0.997	0.000
Z70.1 Counselling related to patient's sexual behaviour and orientation	0.003	0.997	0.000
C67.2 Lateral wall of bladder	0.003	0.997	0.000
Z74.9 Problem related to care-provider dependency, unspecified	0.002	0.997	0.000
Z32.0 Pregnancy, not (yet) confirmed	0.003	0.997	0.000
C67.0 Trigone of bladder	0.003	0.997	0.000
Z75.3 Unavailability and inaccessibility of health-care facilities	0.002	0.997	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.002	0.997	0.000
Z32 Pregnancy examination and test	0.003	0.997	0.000
C67 Malignant neoplasm of bladder	0.003	0.997	0.000
Z32.1 Pregnancy confirmed	0.003	0.997	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.002	0.997	0.000
Z76.3 Healthy person accompanying sick person	0.002	0.997	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.003	0.997	0.000
I82.8 Embolism and thrombosis of other specified veins	0.000	0.998	0.002
J45.0 Predominantly allergic asthma	0.002	0.998	0.000
R30.0 Dysuria	0.000	0.998	0.002
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.002	0.998	0.000
I67.2 Cerebral atherosclerosis	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.000	0.998	0.002
I26 Pulmonary embolism	0.002	0.998	0.000
C67.4 Posterior wall of bladder	0.002	0.998	0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.002	0.998	0.000
H90 Conductive and sensorineural hearing loss	0.002	0.998	0.000
J18.2 Hypostatic pneumonia, unspecified	0.002	0.998	0.000
H20.0 Acute and subacute iridocyclitis	0.000	0.998	0.002
H90.0 Conductive hearing loss, bilateral	0.002	0.998	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.998	0.002
D38.5 Other respiratory organs	0.002	0.998	0.000
H20.9 Iridocyclitis, unspecified	0.000	0.998	0.002
Z71.1 Person with feared complaint in whom no diagnosis is made	0.002	0.998	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.002	0.998	0.000
Z76.9 Persons encountering health services in unspecified circumstances	0.002	0.998	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.002	0.998	0.000
T17.5 Foreign body in bronchus	0.002	0.998	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.002	0.998	0.000
I97.0 Postcardiotomy syndrome	0.002	0.998	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.002	0.998	0.000
C67.7 Urachus	0.002	0.998	0.000
Z32.9 Pregnancy confirmed (erroneous code. See Z321)	0.002	0.998	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.002	0.998	0.000
I38 Endocarditis, valve unspecified	0.002	0.998	0.000
M77.5 Other enthesopathy of foot	0.000	0.998	0.002
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.002	0.998	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
C67.3 Anterior wall of bladder	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
C67.8 Overlapping lesion of bladder	0.002	0.998	0.000
Z71.7 Human immunodeficiency virus [HIV] counselling	0.002	0.998	0.000
Z71.5 Drug abuse counselling and surveillance	0.002	0.998	0.000
Z71.0 Person consulting on behalf of another person	0.002	0.998	0.000
H20 Iridocyclitis	0.000	0.998	0.002
S92.01 Fracture of calcaneus (open)	0.000	0.998	0.002
O34.2 Maternal care due to uterine scar from previous surgery	0.002	0.998	0.000
O34.1 Maternal care for tumour of corpus uteri	0.002	0.998	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.002	0.998	0.000
J18.8 Other pneumonia, organism unspecified	0.002	0.998	0.000
Z71.3 Dietary counselling and surveillance	0.002	0.998	0.000
G95.2 Cord compression, unspecified	0.002	0.998	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.002	0.998	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998	0.000
N75.1 Abscess of Bartholin's gland	0.000	0.998	0.002
Z71.6 Tobacco abuse counselling	0.002	0.998	0.000
Z31 Procreative management	0.002	0.998	0.000
C67.9 Bladder, unspecified	0.002	0.998	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
H90.5 Sensorineural hearing loss, unspecified	0.002	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.000	0.998	0.002
D86.8 Sarcoidosis of other and combined sites	0.000	0.998	0.002
Y84.0 Cardiac catheterisation	0.000	0.998	0.002
Z31.9 Procreative management, unspecified	0.002	0.998	0.000
D75.2 Essential thrombocytosis	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.000	0.998	0.002
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
D38.6 Respiratory organ, unspecified	0.002	0.998	0.000
D38.4 Thymus	0.002	0.998	0.000
D38.3 Mediastinum	0.002	0.998	0.000
D38.2 Pleura	0.002	0.998	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.998	0.002
H60.3 Other infective otitis externa	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.000	0.998	0.002
M77.59 Other enthesopathy of foot-Site unspec	0.000	0.998	0.002
M77.58 Other enthesopathy of foot-Other	0.000	0.998	0.002
M77.56 Other enthesopathy of foot-Lower Leg	0.000	0.998	0.002
M77.55 Other enthesopathy of foot-Pelvic/Thigh	0.000	0.998	0.002
M77.54 Other enthesopathy of foot-Hand	0.000	0.998	0.002
M77.53 Other enthesopathy of foot-Forearm	0.000	0.998	0.002
M77.52 Other enthesopathy of foot-Upper arm	0.000	0.998	0.002
M77.51 Other enthesopathy of foot-Shldr region	0.000	0.998	0.002
M77.50 Other enthesopathy of foot-Mult sites	0.000	0.998	0.002
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.002	0.998	0.000
L83 Acanthosis nigricans	0.002	0.998	0.000
D75.0 Familial erythrocytosis	0.002	0.998	0.000
H20.2 Lens-induced iridocyclitis	0.000	0.998	0.002
V18.0 Driver injured in nontraffic accident	0.000	0.998	0.002
Z31.8 Other procreative management	0.002	0.998	0.000
Z50.8 Care involving use of rehabilitation procedures	0.002	0.998	0.000
N72 Inflammatory disease of cervix uteri	0.002	0.998	0.000
Z38 Liveborn infants according to place of birth	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.000	0.998	0.002
D38.0 Larynx	0.002	0.998	0.000
Z31.3 Other assisted fertilisation methods	0.002	0.998	0.000
Z36.8 Other antenatal screening	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.000	0.998	0.002
Z71.2 Person consulting for explanation of investigation findings	0.002	0.998	0.000
H60.5 Acute otitis externa, non-infective	0.002	0.998	0.000
Z71.9 Counselling, unspecified	0.002	0.998	0.000
D75 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
A02.0 Salmonella gastro-enteritis	0.000	0.998	0.002
H60.0 Abscess of external ear	0.002	0.998	0.000
S92.4 Fracture of great toe	0.000	0.998	0.002
H60 Otitis externa	0.002	0.998	0.000
H60.8 Other otitis externa	0.002	0.998	0.000
Z31.6 General counselling and advice on procreation	0.001	0.998	0.000
Z31.5 Genetic counselling	0.001	0.998	0.000
Z31.1 Artifical insemination	0.001	0.998	0.000
C67.6 Ureteric orifice	0.002	0.998	0.000
S92.5 Fracture of other toe	0.000	0.998	0.002
S92.1 Fracture of talus	0.000	0.998	0.002
W51.9 Unspecified place	0.000	0.998	0.002
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.002	0.998	0.000
N85.2 Hypertrophy of uterus	0.000	0.998	0.002
X23.0 Home	0.000	0.998	0.002
I60 Subarachnoid haemorrhage	0.002	0.998	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.002	0.998	0.000
G80.1 Spastic diplegia	0.002	0.998	0.000
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.998	0.001
R45.8 Other symptoms and signs involving emotional state	0.000	0.998	0.002
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.000	0.998	0.001
H60.1 Cellulitis of external ear	0.002	0.998	0.000
H90.3 Sensorineural hearing loss, bilateral	0.002	0.998	0.000
L73.2 Hidradenitis suppurativa	0.001	0.998	0.000
I97.1 Other functional disturbances following cardiac surgery	0.001	0.998	0.001
Z31.4 Procreative investigation and testing	0.001	0.998	0.000
S92.50 Fracture of other toe (closed)	0.000	0.998	0.001
Z38.8 Other multiple, unspecified as to place of birth	0.001	0.998	0.000
Z38.7 Other multiple, born outside hospital	0.001	0.998	0.000
Z38.6 Other multiple, born in hospital	0.001	0.998	0.000
Z38.5 Twin, unspecified as to place of birth	0.001	0.998	0.000
Z38.4 Twin, born outside hospital	0.001	0.998	0.000
Z38.3 Twin, born in hospital	0.001	0.998	0.000
Z38.2 Singleton, unspecified as to place of birth	0.001	0.998	0.000
Z38.1 Singleton, born outside hospital	0.001	0.998	0.000
S92.10 Fracture of talus (closed)	0.000	0.998	0.001
H20.1 Chronic iridocyclitis	0.000	0.998	0.001
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.998	0.001
I67 Other cerebrovascular diseases	0.002	0.998	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.999	0.001
H18.6 Keratoconus	0.000	0.999	0.001
I67.0 Dissection of cerebral arteries, nonruptured	0.001	0.999	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.001	0.999	0.000
G80.2 Infantile hemiplegia	0.001	0.999	0.000
L60.8 Other nail disorders	0.001	0.999	0.000
R30.1 Vesical tenesmus	0.000	0.999	0.001
S92.51 Fracture of other toe (open)	0.000	0.999	0.001
H15.8 Other disorders of sclera	0.000	0.999	0.001
J18.9 Pneumonia, unspecified	0.001	0.999	0.000
O34.6 Maternal care for abnormality of vagina	0.001	0.999	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.001	0.999	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.001	0.999	0.000
D12.2 Ascending colon	0.001	0.999	0.000
D84.9 Immunodeficiency, unspecified	0.000	0.999	0.001
I67.4 Hypertensive encephalopathy	0.001	0.999	0.000
I60-I69 Cerebrovascular diseases	0.001	0.999	0.000
S92.11 Fracture of talus (open)	0.000	0.999	0.001
H60.2 Malignant otitis externa	0.001	0.999	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.001	0.999	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.001	0.999	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.001	0.999	0.000
O34.0 Maternal care for congenital malformation of uterus	0.001	0.999	0.000
S92.9 Fracture of foot, unspecified	0.000	0.999	0.001
Z38.0 Singleton, born in hospital	0.001	0.999	0.000
Z90.5 Acquired absence of kidney	0.000	0.999	0.001
I68 Cerebrovascular disorders in diseases classified elsewhere	0.001	0.999	0.000
H17.9 Corneal scar and opacity, unspecified	0.000	0.999	0.001
S92.2 Fracture of other tarsal bone(s)	0.000	0.999	0.001
Z45.1 Adjustment and management of infusion pump	0.000	0.999	0.001
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.001	0.999	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.001	0.999	0.000
I67.5 Moyamoya disease	0.001	0.999	0.000
I67.3 Progressive vascular leukoencephalopathy	0.001	0.999	0.000
I68.0 Cerebral amyloid angiopathy	0.001	0.999	0.000
Z31.2 In vitro fertilisation	0.001	0.999	0.000
D25 Leiomyoma of uterus	0.000	0.999	0.001
R30 Pain associated with micturition	0.000	0.999	0.001
S92.41 Fracture of great toe (open)	0.000	0.999	0.001
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.001	0.999	0.000
F30.9 Manic episode, unspecified	0.000	0.999	0.001
G80.9 Infantile cerebral palsy, unspecified	0.001	0.999	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.001	0.999	0.000
T82.3 Mechanical complication of other vascular grafts	0.001	0.999	0.000
C67.5 Bladder neck	0.001	0.999	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.001	0.999	0.000
F50.0 Anorexia nervosa	0.000	0.999	0.001
O34.3 Maternal care for cervical incompetence	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations