TreeWAS – Variant ID: rs494459

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I08.0 Disorders of both mitral and aortic valves	0.071	0.929	0.000
I08 Multiple valve diseases	0.060	0.940	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.060	0.940	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.055	0.945	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.049	0.951	0.000
I08.9 Multiple valve disease, unspecified	0.046	0.954	0.000
S91 Open wound of ankle and foot	0.042	0.958	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.041	0.959	0.000
S91.3 Open wound of other parts of foot	0.041	0.959	0.000
S90-S99 Injuries to the ankle and foot	0.041	0.959	0.000
S90 Superficial injury of ankle and foot	0.040	0.960	0.000
S91.0 Open wound of ankle	0.037	0.963	0.000
S99 Other and unspecified injuries of ankle and foot	0.036	0.964	0.000
S90.3 Contusion of other and unspecified parts of foot	0.035	0.965	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.035	0.965	0.000
S92 Fracture of foot, except ankle	0.034	0.966	0.000
S92.5 Fracture of other toe	0.034	0.966	0.000
S91.2 Open wound of toe(s) with damage to nail	0.034	0.966	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.033	0.967	0.000
S99.8 Other specified injuries of ankle and foot	0.033	0.967	0.000
S90.8 Other superficial injuries of ankle and foot	0.032	0.968	0.000
S90.0 Contusion of ankle	0.032	0.968	0.000
S92.51 Fracture of other toe (open)	0.032	0.968	0.000
S91.1 Open wound of toe(s) without damage to nail	0.032	0.968	0.000
S91.7 Multiple open wounds of ankle and foot	0.030	0.969	0.000
S90.1 Contusion of toe(s) without damage to nail	0.030	0.969	0.000
S92.50 Fracture of other toe (closed)	0.030	0.970	0.000
S98 Traumatic amputation of ankle and foot	0.029	0.970	0.000
S95 Injury of blood vessels at ankle and foot level	0.029	0.970	0.000
S94 Injury of nerves at ankle and foot level	0.029	0.970	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.029	0.971	0.000
S90.2 Contusion of toe(s) with damage to nail	0.029	0.971	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.029	0.971	0.000
S97 Crushing injury of ankle and foot	0.028	0.972	0.000
S99.9 Unspecified injury of ankle and foot	0.027	0.973	0.000
I08.8 Other multiple valve diseases	0.026	0.973	0.000
S92.9 Fracture of foot, unspecified	0.026	0.973	0.000
S92.4 Fracture of great toe	0.026	0.973	0.000
S99.7 Multiple injuries of ankle and foot	0.026	0.974	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.025	0.975	0.000
S92.1 Fracture of talus	0.025	0.975	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.024	0.976	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.024	0.976	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.024	0.976	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.023	0.976	0.000
S92.2 Fracture of other tarsal bone(s)	0.023	0.977	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.023	0.977	0.000
S92.41 Fracture of great toe (open)	0.023	0.977	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.021	0.979	0.000
S94.8 Injury of other nerves at ankle and foot level	0.021	0.979	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.021	0.979	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.021	0.979	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.021	0.979	0.000
S94.1 Injury of medial plantar nerve	0.021	0.979	0.000
S94.0 Injury of lateral plantar nerve	0.021	0.979	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.021	0.979	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.021	0.979	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.021	0.979	0.000
S95.2 Injury of dorsal vein of foot	0.021	0.979	0.000
S95.1 Injury of plantar artery of foot	0.021	0.979	0.000
S95.0 Injury of dorsal artery of foot	0.021	0.979	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.021	0.979	0.000
S98.3 Traumatic amputation of other parts of foot	0.021	0.979	0.000
S98.2 Traumatic amputation of two or more toes	0.021	0.979	0.000
S98.1 Traumatic amputation of one toe	0.021	0.979	0.000
S98.0 Traumatic amputation of foot at ankle level	0.021	0.979	0.000
S93.0 Dislocation of ankle joint	0.021	0.979	0.000
S92.90 Fracture of foot, unspecified (closed)	0.021	0.979	0.000
S97.1 Crushing injury of toe(s)	0.020	0.980	0.000
S97.0 Crushing injury of ankle	0.020	0.980	0.000
S92.7 Multiple fractures of foot	0.020	0.980	0.000
S92.91 Fracture of foot, unspecified (open)	0.019	0.981	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.019	0.981	0.000
S92.0 Fracture of calcaneus	0.019	0.981	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.019	0.981	0.000
S93.4 Sprain and strain of ankle	0.018	0.982	0.000
S93.5 Sprain and strain of toe(s)	0.018	0.982	0.000
S92.3 Fracture of metatarsal bone	0.018	0.982	0.000
S92.11 Fracture of talus (open)	0.018	0.982	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.018	0.982	0.000
S92.10 Fracture of talus (closed)	0.018	0.982	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.017	0.983	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.015	0.984	0.000
S92.40 Fracture of great toe (closed)	0.015	0.985	0.000
S92.01 Fracture of calcaneus (open)	0.015	0.985	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.015	0.985	0.000
S92.71 Multiple fractures of foot (open)	0.014	0.985	0.000
I27.2 Other secondary pulmonary hypertension	0.014	0.986	0.000
S93.40 Sprain of unspecified ligament of ankle	0.013	0.986	0.000
S92.31 Fracture of metatarsal bone (open)	0.013	0.987	0.000
S93.1 Dislocation of toe(s)	0.013	0.987	0.000
M25.57 Pain in joint (Ankle and foot)	0.000	0.989	0.011
S92.70 Multiple fractures of foot (closed)	0.010	0.990	0.001
G93.9 Disorder of brain, unspecified	0.010	0.990	0.000
I27 Other pulmonary heart diseases	0.010	0.990	0.000
I27.0 Primary pulmonary hypertension	0.010	0.990	0.000
I05-I09 Chronic rheumatic heart diseases	0.009	0.991	0.000
E13.9 Without complications	0.000	0.992	0.008
F33.9 Recurrent depressive disorder, unspecified	0.008	0.992	0.000
I27.1 Kyphoscoliotic heart disease	0.007	0.993	0.000
I27.8 Other specified pulmonary heart diseases	0.007	0.993	0.000
S92.30 Fracture of metatarsal bone (closed)	0.006	0.993	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.994	0.006
I27.9 Pulmonary heart disease, unspecified	0.006	0.994	0.000
R16.1 Splenomegaly, not elsewhere classified	0.000	0.994	0.006
F45.8 Other somatoform disorders	0.006	0.994	0.000
I09 Other rheumatic heart diseases	0.006	0.994	0.000
I06 Rheumatic aortic valve diseases	0.006	0.994	0.000
F33 Recurrent depressive disorder	0.006	0.994	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.005	0.995	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.005	0.995	0.000
E13 Other specified diabetes mellitus	0.000	0.995	0.005
I07 Rheumatic tricuspid valve diseases	0.005	0.995	0.000
J32.9 Chronic sinusitis, unspecified	0.000	0.995	0.005
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.000	0.995	0.005
E14.9 Without complications	0.000	0.995	0.005
I06.9 Rheumatic aortic valve disease, unspecified	0.005	0.995	0.000
H83.0 Labyrinthitis	0.000	0.995	0.005
I09.8 Other specified rheumatic heart diseases	0.004	0.995	0.000
I09.2 Chronic rheumatic pericarditis	0.004	0.995	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.004	0.995	0.000
I09.0 Rheumatic myocarditis	0.004	0.995	0.000
I06.8 Other rheumatic aortic valve diseases	0.004	0.995	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.004	0.995	0.000
N05.9 Unspecified	0.004	0.996	0.000
F33.8 Other recurrent depressive disorders	0.004	0.996	0.000
I09.9 Rheumatic heart disease, unspecified	0.004	0.996	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.004	0.996	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.004	0.996	0.000
I06.0 Rheumatic aortic stenosis	0.004	0.996	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.000	0.996	0.004
E14 Unspecified diabetes mellitus	0.000	0.996	0.004
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.996	0.004
G91.0 Communicating hydrocephalus	0.004	0.996	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.000	0.996	0.004
G91.1 Obstructive hydrocephalus	0.004	0.996	0.000
I87.8 Other specified disorders of veins	0.000	0.996	0.004
E13.8 With unspecified complications	0.000	0.996	0.004
E13.7 With multiple complications	0.000	0.996	0.004
E13.6 With other specified complications	0.000	0.996	0.004
E13.5 With peripheral circulatory complications	0.000	0.996	0.004
E13.4 With neurological complications	0.000	0.996	0.004
E13.3 With ophthalmic complications	0.000	0.996	0.004
E13.2 With renal complications	0.000	0.996	0.004
E13.1 With ketoacidosis	0.000	0.996	0.004
E13.0 With coma	0.000	0.996	0.004
I06.1 Rheumatic aortic insufficiency	0.004	0.996	0.000
G91 Hydrocephalus	0.004	0.996	0.000
I07.9 Tricuspid valve disease, unspecified	0.004	0.996	0.000
I07.8 Other tricuspid valve diseases	0.004	0.996	0.000
I07.2 Tricuspid stenosis with insufficiency	0.004	0.996	0.000
I07.0 Tricuspid stenosis	0.004	0.996	0.000
E14.6 With other specified complications	0.000	0.996	0.004
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.004	0.996	0.000
E14.5 With peripheral circulatory complications	0.000	0.996	0.004
E14.4 With neurological complications	0.000	0.996	0.004
G91.3 Posttraumatic hydrocephalus, unspecified	0.004	0.996	0.000
F22.0 Delusional disorder	0.004	0.996	0.000
E14.1 With ketoacidosis	0.000	0.996	0.004
E14.2 Withrenal complications	0.000	0.996	0.003
E10.1 With ketoacidosis	0.000	0.997	0.003
E14.8 With unspecified complications	0.000	0.997	0.003
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.003	0.997	0.000
E14.7 With multiple complications	0.000	0.997	0.003
E14.0 With coma	0.000	0.997	0.003
G91.8 Other hydrocephalus	0.003	0.997	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.000	0.997	0.003
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.000	0.997	0.003
I05 Rheumatic mitral valve diseases	0.003	0.997	0.000
J32.4 Chronic pansinusitis	0.000	0.997	0.003
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.003	0.997	0.000
M95.0 Acquired deformity of nose	0.003	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
F31 Bipolar affective disorder	0.003	0.997	0.000
F30-F39 Mood [affective] disorders	0.003	0.997	0.000
F45 Somatoform disorders	0.003	0.997	0.000
E10-E14 Diabetes mellitus	0.000	0.997	0.003
I87 Other disorders of veins	0.000	0.997	0.003
S92.00 Fracture of calcaneus (closed)	0.002	0.997	0.001
G91.2 Normal-pressure hydrocephalus	0.003	0.997	0.000
F30.9 Manic episode, unspecified	0.003	0.997	0.000
H83 Other diseases of inner ear	0.000	0.997	0.003
K62.6 Ulcer of anus and rectum	0.000	0.997	0.003
F34 Persistent mood [affective] disorders	0.003	0.997	0.000
G91.9 Hydrocephalus, unspecified	0.003	0.997	0.000
L98.7 Excessive and redundant skin and subcutaneous tissue	0.003	0.997	0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue	0.003	0.997	0.000
L98.4 Chronic ulcer of skin, not elsewhere classified	0.003	0.997	0.000
L98.3 Eosinophilic cellulitis [Wells]	0.003	0.997	0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]	0.003	0.997	0.000
F31.9 Bipolar affective disorder, unspecified	0.003	0.997	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.003	0.997	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.003	0.997	0.000
F31.8 Other bipolar affective disorders	0.003	0.997	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.000	0.997	0.003
Z50.8 Care involving use of rehabilitation procedures	0.003	0.997	0.000
F38 Other mood [affective] disorders	0.003	0.997	0.000
Y88 Sequelae of surgical and medical care as external cause	0.000	0.997	0.003
H83.8 Other specified diseases of inner ear	0.000	0.997	0.003
L98.1 Factitial dermatitis	0.003	0.997	0.000
F45.3 Somatoform autonomic dysfunction	0.003	0.997	0.000
F30 Manic episode	0.003	0.997	0.000
I28 Other diseases of pulmonary vessels	0.003	0.997	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.997	0.003
F34.0 Cyclothymia	0.003	0.997	0.000
I89.0 Lymphoedema, not elsewhere classified	0.003	0.997	0.000
I05.1 Rheumatic mitral insufficiency	0.003	0.997	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.003	0.997	0.000
H83.9 Disease of inner ear, unspecified	0.000	0.997	0.003
F45.2 Hypochondriacal disorder	0.003	0.997	0.000
I05.8 Other mitral valve diseases	0.002	0.997	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.003	0.997	0.000
F34.1 Dysthymia	0.003	0.997	0.000
L98.5 Mucinosis of skin	0.002	0.997	0.000
F45.9 Somatoform disorder, unspecified	0.002	0.997	0.000
F45.1 Undifferentiated somatoform disorder	0.002	0.997	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.997	0.003
E12 Malnutrition-related diabetes mellitus	0.000	0.997	0.002
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.003	0.997	0.000
D10.3 Other and unspecified parts of mouth	0.003	0.997	0.000
I87.0 Postphlebitic syndrome	0.000	0.997	0.002
I07.1 Tricuspid insufficiency	0.002	0.997	0.000
H83.3 Noise effects on inner ear	0.000	0.997	0.002
H83.1 Labyrinthine fistula	0.000	0.997	0.002
E10 Insulin-dependent diabetes mellitus	0.000	0.997	0.003
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.002	0.998	0.000
F38.0 Other single mood [affective] disorders	0.002	0.998	0.000
N05.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.002	0.998	0.000
F34.8 Other persistent mood [affective] disorders	0.002	0.998	0.000
F45.4 Persistent somatoform pain disorder	0.002	0.998	0.000
F38.8 Other specified mood [affective] disorders	0.002	0.998	0.000
F45.0 Somatisation disorder	0.002	0.998	0.000
G56.0 Carpal tunnel syndrome	0.002	0.998	0.000
N05 Unspecified nephritic syndrome	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.002	0.998	0.000
I28.8 Other specified diseases of pulmonary vessels	0.002	0.998	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.000	0.998	0.002
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.000	0.998	0.002
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.000	0.998	0.002
F31.6 Bipolar affective disorder, current episode mixed	0.002	0.998	0.000
H83.2 Labyrinthine dysfunction	0.000	0.998	0.002
I87.9 Disorder of vein, unspecified	0.000	0.998	0.002
E10.5 With peripheral circulatory complications	0.000	0.998	0.002
I05.2 Mitral stenosis with insufficiency	0.002	0.998	0.000
F38.1 Other recurrent mood [affective] disorders	0.002	0.998	0.000
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.000	0.998	0.002
F30.8 Other manic episodes	0.002	0.998	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.002	0.998	0.000
I28.1 Aneurysm of pulmonary artery	0.002	0.998	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.002	0.998	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.002	0.998	0.000
J33.0 Polyp of nasal cavity	0.000	0.998	0.002
E10.2 With renal complications	0.000	0.998	0.002
M95.2 Other acquired deformity of head	0.002	0.998	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.998	0.002
J32 Chronic sinusitis	0.000	0.998	0.002
G97.8 Other postprocedural disorders of nervous system	0.002	0.998	0.000
I05.0 Mitral stenosis	0.002	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.002	0.998	0.000
E10.3 With ophthalmic complications	0.000	0.998	0.002
E12.9 Without complications	0.000	0.998	0.002
E12.8 With unspecified complications	0.000	0.998	0.002
E12.7 With multiple complications	0.000	0.998	0.002
E12.6 With other specified complications	0.000	0.998	0.002
E12.5 With peripheral circulatory complications	0.000	0.998	0.002
E12.4 With neurological complications	0.000	0.998	0.002
E12.3 With ophthalmic complications	0.000	0.998	0.002
E12.2 With renal complications	0.000	0.998	0.002
E12.1 With ketoacidosis	0.000	0.998	0.002
E12.0 With coma	0.000	0.998	0.002
J32.3 Chronic sphenoidal sinusitis	0.000	0.998	0.002
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.998	0.000
F22 Persistent delusional disorders	0.002	0.998	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.002	0.998	0.000
I87.1 Compression of vein	0.000	0.998	0.002
N87.1 Moderate cervical dysplasia	0.002	0.998	0.000
F30.1 Mania without psychotic symptoms	0.002	0.998	0.000
F39 Unspecified mood [affective] disorder	0.002	0.998	0.000
C15.9 Oesophagus, unspecified	0.002	0.998	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.998	0.002
T84.1 Mechanical complication of internal fixation device of bones of limb	0.002	0.998	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
O69.8 Labour and delivery complicated by other cord complications	0.002	0.998	0.000
F30.0 Hypomania	0.002	0.998	0.000
N05.6 Dense deposit disease	0.002	0.998	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N05.0 Minor glomerular abnormality	0.002	0.998	0.000
D46.2 Refractory anaemia with excess of blasts	0.000	0.998	0.002
V23.4 Driver injured in traffic accident	0.000	0.998	0.002
E10.0 With coma	0.000	0.998	0.002
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
N05.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.000	0.998	0.002
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.998	0.002
E10.7 With multiple complications	0.000	0.998	0.002
Z83.5 Family history of eye and ear disorders	0.000	0.998	0.002
M77.12 Lateral epicondylitis (Upper arm)	0.002	0.998	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.000	0.998	0.002
E10.8 With unspecified complications	0.000	0.998	0.002
M16.0 Primary coxarthrosis, bilateral	0.002	0.998	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.002	0.998	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.002	0.998	0.000
M95.5 Acquired deformity of pelvis	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
M95.3 Acquired deformity of neck	0.002	0.998	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.002	0.998	0.000
D10.1 Tongue	0.002	0.998	0.000
F22.8 Other persistent delusional disorders	0.002	0.998	0.000
F30.2 Mania with psychotic symptoms	0.002	0.998	0.000
E14.3 With ophthalmic complications	0.000	0.998	0.002
M95.1 Cauliflower ear	0.002	0.998	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.002	0.998	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.002	0.998	0.000
O69.3 Labour and delivery complicated by short cord	0.002	0.998	0.000
D46 Myelodysplastic syndromes	0.000	0.998	0.002
C67.4 Posterior wall of bladder	0.002	0.998	0.000
F22.9 Persistent delusional disorder, unspecified	0.002	0.998	0.000
C15.5 Lower third of oesophagus	0.002	0.998	0.000
L98.0 Pyogenic granuloma	0.002	0.998	0.000
D46.4 Refractory anaemia, unspecified	0.000	0.998	0.002
O75.0 Maternal distress during labour and delivery	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T90.9 Sequelae of unspecified injury of head	0.000	0.998	0.002
I26 Pulmonary embolism	0.002	0.998	0.000
M95.4 Acquired deformity of chest and rib	0.002	0.998	0.000
N20.2 Calculus of kidney with calculus of ureter	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.002	0.998	0.000
N92.4 Excessive bleeding in the premenopausal period	0.000	0.998	0.002
Z42 Follow-up care involving plastic surgery	0.000	0.998	0.002
C34.2 Middle lobe, bronchus or lung	0.002	0.998	0.000
E10.6 With other specified complications	0.000	0.998	0.001
K25.3 Acute without haemorrhage or perforation	0.000	0.998	0.002
Q76.9 Congenital malformation of bony thorax, unspecified	0.001	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.001	0.998	0.000
Q76.7 Congenital malformation of sternum	0.001	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.001	0.998	0.000
Q76.5 Cervical rib	0.001	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.001	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.001	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.002	0.998	0.000
R00.8 Other and unspecified abnormalities of heart beat	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
J30.4 Allergic rhinitis, unspecified	0.000	0.998	0.002
K01.0 Embedded teeth	0.002	0.998	0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.001	0.998	0.000
D46.1 Refractory anaemia with sideroblasts	0.000	0.998	0.001
G97.9 Postprocedural disorder of nervous system, unspecified	0.001	0.998	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.001	0.998	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.002	0.998	0.000
I49.4 Other and unspecified premature depolarisation	0.002	0.998	0.000
J32.1 Chronic frontal sinusitis	0.000	0.998	0.001
Q65.1 Congenital dislocation of hip, bilateral	0.001	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.001	0.998	0.000
T44.0 Anticholinesterase agents	0.001	0.998	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.002	0.998	0.000
D10 Benign neoplasm of mouth and pharynx	0.002	0.998	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.998	0.001
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.998	0.001
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.998	0.001
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.998	0.002
B00.1 Herpesviral vesicular dermatitis	0.002	0.998	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.002	0.998	0.000
O36.9 Maternal care for foetal problem, unspecified	0.002	0.998	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.001	0.998	0.000
Z85.9 Personal history of malignant neoplasm, unspecified	0.000	0.998	0.002
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.999	0.001
G97.1 Other reaction to spinal and lumbar puncture	0.001	0.999	0.000
N05.8 Other	0.001	0.999	0.000
D10.9 Pharynx, unspecified	0.001	0.999	0.000
B00.5 Herpesviral ocular disease	0.001	0.999	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.001	0.999	0.000
Q44.6 Cystic disease of liver	0.000	0.999	0.001
Q65.9 Congenital deformity of hip, unspecified	0.001	0.999	0.000
Q65.6 Unstable hip	0.001	0.999	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.001	0.999	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.001	0.999	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.001	0.999	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.001	0.999	0.000
I44.3 Other and unspecified atrioventricular block	0.000	0.999	0.001
D10.7 Hypopharynx	0.001	0.999	0.000
D10.6 Nasopharynx	0.001	0.999	0.000
D10.2 Floor of mouth	0.001	0.999	0.000
N82.4 Other female intestinal-genital tract fistulae	0.000	0.999	0.001
C85.1 B-cell lymphoma, unspecified	0.000	0.999	0.001
D10.0 Lip	0.001	0.999	0.000
Q23.1 Congenital insufficiency of aortic valve	0.001	0.999	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.001	0.999	0.000
B00 Herpesviral [herpes simplex] infections	0.001	0.999	0.000
Q79.6 Ehlers-Danlos syndrome	0.001	0.999	0.000
R52.0 Acute pain	0.001	0.999	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.000	0.999	0.001
N36.2 Urethral caruncle	0.000	0.999	0.001
Q65.2 Congenital dislocation of hip, unspecified	0.001	0.999	0.000
Z11.5 Special screening examination for other viral diseases	0.001	0.999	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.001	0.999	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.000	0.999	0.001
D10.4 Tonsil	0.001	0.999	0.000
I05.9 Mitral valve disease, unspecified	0.001	0.999	0.001
D46.7 Other myelodysplastic syndromes	0.000	0.999	0.001
C15 Malignant neoplasm of oesophagus	0.001	0.999	0.000
G62.9 Polyneuropathy, unspecified	0.000	0.999	0.001
Q79.8 Other congenital malformations of musculoskeletal system	0.001	0.999	0.000
T91.3 Sequelae of injury of spinal cord	0.000	0.999	0.001
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.001	0.999	0.000
J32.0 Chronic maxillary sinusitis	0.000	0.999	0.001
Q89.2 Congenital malformations of other endocrine glands	0.001	0.999	0.000
B00.7 Disseminated herpesviral disease	0.001	0.999	0.000
B00.3 Herpesviral meningitis	0.001	0.999	0.000
B00.0 Eczema herpeticum	0.001	0.999	0.000
G96.0 Cerebrospinal fluid leak	0.001	0.999	0.000
H81.2 Vestibular neuronitis	0.000	0.999	0.001
Q79.1 Other congenital malformations of diaphragm	0.001	0.999	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.001	0.999	0.000
B00.4 Herpesviral encephalitis	0.001	0.999	0.000
D10.5 Other parts of oropharynx	0.001	0.999	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.000	0.999	0.001
N82.3 Fistula of vagina to large intestine	0.000	0.999	0.001
O34.8 Maternal care for other abnormalities of pelvic organs	0.000	0.999	0.001
O43.1 Malformation of placenta	0.001	0.999	0.000
Q78.0 Osteogenesis imperfecta	0.001	0.999	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.001	0.999	0.000
Q79.5 Other congenital malformations of abdominal wall	0.001	0.999	0.000
Q79.4 Prune belly syndrome	0.001	0.999	0.000
Q79.3 Gastroschisis	0.001	0.999	0.000
Q79.2 Exomphalos	0.001	0.999	0.000
Q79.0 Congenital diaphragmatic hernia	0.001	0.999	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.001	0.999	0.000
Z42.9 Follow-up care involving plastic surgery, unspecified	0.000	0.999	0.001
G93 Other disorders of brain	0.001	0.999	0.000
B00.9 Herpesviral infection, unspecified	0.001	0.999	0.000
C15.1 Thoracic part of oesophagus	0.001	0.999	0.000
G94.1 Hydrocephalus in neoplastic disease	0.001	0.999	0.000
Q78 Other osteochondrodysplasias	0.001	0.999	0.000
C15.8 Overlapping lesion of oesophagus	0.001	0.999	0.000
C15.2 Abdominal part of oesophagus	0.001	0.999	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.001	0.999	0.000
L73.2 Hidradenitis suppurativa	0.001	0.999	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.999	0.001
B00.8 Other forms of herpesviral infection	0.001	0.999	0.000
S61.7 Multiple open wounds of wrist and hand	0.000	0.999	0.001
G94 Other disorders of brain in diseases classified elsewhere	0.001	0.999	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.001	0.999	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.999	0.001
E10.4 With neurological complications	0.000	0.999	0.001
O69.1 Labour and delivery complicated by cord around neck, with compression	0.001	0.999	0.000
Q75 Other congenital malformations of skull and face bones	0.001	0.999	0.000
G90-G99 Other disorders of the nervous system	0.001	0.999	0.000
G93.7 Reye's syndrome	0.001	0.999	0.000
Q75.4 Mandibulofacial dysostosis	0.001	0.999	0.000
B02.3 Zoster ocular disease	0.001	0.999	0.000
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.000	0.999	0.001
O75.8 Other specified complications of labour and delivery	0.000	0.999	0.001
Q78.9 Osteochondrodysplasia, unspecified	0.001	0.999	0.000
Q78.8 Other specified osteochondrodysplasias	0.001	0.999	0.000
Q78.6 Multiple congenital exostoses	0.001	0.999	0.000
Q78.5 Metaphyseal dysplasia	0.001	0.999	0.000
Q78.4 Enchondromatosis	0.001	0.999	0.000
Q78.3 Progressive diaphyseal dysplasia	0.001	0.999	0.000
Q78.2 Osteopetrosis	0.001	0.999	0.000
Q78.1 Polyostotic fibrous dysplasia	0.001	0.999	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.001	0.999	0.000
Q70 Syndactyly	0.001	0.999	0.000
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
C81.9 Hodgkin's disease, unspecified	0.000	0.999	0.001
D33.0 Brain, supratentorial	0.001	0.999	0.000
D36.7 Other specified sites	0.000	0.999	0.001
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.999	0.001
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.001	0.999	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
I77.8 Other specified disorders of arteries and arterioles	0.001	0.999	0.000
Q73 Reduction defects of unspecified limb	0.001	0.999	0.000
Q72 Reduction defects of lower limb	0.001	0.999	0.000
Q71 Reduction defects of upper limb	0.001	0.999	0.000
Q69 Polydactyly	0.001	0.999	0.000
Q68 Other congenital musculoskeletal deformities	0.001	0.999	0.000
C15.0 Cervical part of oesophagus	0.001	0.999	0.000
K55.8 Other vascular disorders of intestine	0.000	0.999	0.001
N49.2 Inflammatory disorders of scrotum	0.001	0.999	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.000	0.999	0.001
Q70.3 Webbed toes	0.001	0.999	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.001	0.999	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.001	0.999	0.000
Q75.5 Oculomandibular dysostosis	0.001	0.999	0.000
Q75.3 Macrocephaly	0.001	0.999	0.000
Q75.2 Hypertelorism	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations