TreeWAS – Variant ID: rs4949718

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I08.0 Disorders of both mitral and aortic valves	0.000	0.947	0.053
S01 Open wound of head	0.046	0.954	0.000
S01.1 Open wound of eyelid and periocular area	0.044	0.956	0.000
S01.5 Open wound of lip and oral cavity	0.044	0.956	0.000
S01.0 Open wound of scalp	0.043	0.957	0.000
S01.7 Multiple open wounds of head	0.042	0.958	0.000
S01.9 Open wound of head, part unspecified	0.040	0.960	0.000
S01.2 Open wound of nose	0.038	0.962	0.000
S01.4 Open wound of cheek and temporomandibular area	0.036	0.964	0.000
S01.3 Open wound of ear	0.034	0.966	0.000
H35.3 Degeneration of macula and posterior pole	0.000	0.975	0.025
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.024	0.976	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.023	0.977	0.000
I60 Subarachnoid haemorrhage	0.022	0.978	0.000
N75.1 Abscess of Bartholin's gland	0.022	0.978	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.979	0.021
R01.1 Cardiac murmur, unspecified	0.000	0.981	0.019
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.019	0.981	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.000	0.981	0.019
I60.4 Subarachnoid haemorrhage from basilar artery	0.017	0.983	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.017	0.983	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.017	0.983	0.000
K29.4 Chronic atrophic gastritis	0.017	0.983	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.984	0.016
I60.5 Subarachnoid haemorrhage from vertebral artery	0.016	0.984	0.000
I08 Multiple valve diseases	0.000	0.985	0.015
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.015	0.985	0.000
S01.8 Open wound of other parts of head	0.015	0.985	0.000
Z02.8 Other examinations for administrative purposes	0.014	0.986	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.986	0.014
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.986	0.013
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.987	0.013
L03.2 Cellulitis of face	0.000	0.987	0.013
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.012	0.988	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.988	0.012
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.988	0.012
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.988	0.012
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.988	0.012
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.989	0.011
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.989	0.011
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.989	0.011
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.989	0.011
I08.9 Multiple valve disease, unspecified	0.000	0.989	0.011
I60.8 Other subarachnoid haemorrhage	0.010	0.990	0.000
N81.2 Incomplete uterovaginal prolapse	0.000	0.990	0.010
I08.8 Other multiple valve diseases	0.000	0.991	0.009
H35 Other retinal disorders	0.000	0.991	0.009
H35.0 Background retinopathy and retinal vascular changes	0.000	0.991	0.009
D03.3 Melanoma in situ of other and unspecified parts of face	0.000	0.991	0.009
K73.9 Chronic hepatitis, unspecified	0.008	0.992	0.000
H35.4 Peripheral retinal degeneration	0.000	0.992	0.008
K75.8 Other specified inflammatory liver diseases	0.008	0.992	0.000
R01 Cardiac murmurs and other cardiac sounds	0.000	0.992	0.008
N75 Diseases of Bartholin's gland	0.008	0.992	0.000
S42.00 Fracture of clavicle (closed)	0.008	0.992	0.000
K73 Chronic hepatitis, not elsewhere classified	0.008	0.992	0.000
K75 Other inflammatory liver diseases	0.008	0.992	0.000
H35.2 Other proliferative retinopathy	0.000	0.992	0.008
M05 Seropositive rheumatoid arthritis	0.000	0.993	0.007
H35.5 Hereditary retinal dystrophy	0.000	0.993	0.007
K72.9 Hepatic failure, unspecified	0.007	0.993	0.000
H35.7 Separation of retinal layers	0.000	0.993	0.007
K70-K77 Diseases of liver	0.007	0.993	0.000
K74 Fibrosis and cirrhosis of liver	0.007	0.993	0.000
S30.1 Contusion of abdominal wall	0.000	0.993	0.007
K72 Hepatic failure, not elsewhere classified	0.007	0.993	0.000
H35.1 Retinopathy of prematurity	0.000	0.993	0.007
K74.0 Hepatic fibrosis	0.007	0.993	0.000
K75.4 Autoimmune hepatitis	0.007	0.993	0.000
S30.0 Contusion of lower back and pelvis	0.000	0.993	0.007
K74.3 Primary biliary cirrhosis	0.007	0.993	0.000
K71 Toxic liver disease	0.006	0.994	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.006	0.994	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.994	0.006
Z02 Examination and encounter for administrative purposes	0.006	0.994	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.006	0.994	0.000
K74.5 Biliary cirrhosis, unspecified	0.006	0.994	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.006	0.994	0.000
R01.2 Other cardiac sounds	0.000	0.994	0.006
N75.9 Disease of Bartholin's gland, unspecified	0.006	0.994	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.000	0.994	0.006
K74.1 Hepatic sclerosis	0.006	0.994	0.000
I65.2 Occlusion and stenosis of carotid artery	0.006	0.994	0.000
K72.1 Chronic hepatic failure	0.006	0.994	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.006	0.994	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.006	0.994	0.000
K75.2 Nonspecific reactive hepatitis	0.006	0.994	0.000
K75.1 Phlebitis of portal vein	0.006	0.994	0.000
N75.0 Cyst of Bartholin's gland	0.006	0.994	0.000
M05.2 Rheumatoid vasculitis	0.000	0.994	0.005
R01.0 Benign and innocent cardiac murmurs	0.000	0.994	0.005
K75.0 Abscess of liver	0.005	0.994	0.000
K77 Liver disorders in diseases classified elsewhere	0.005	0.994	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.994	0.005
M05.0 Felty's syndrome	0.000	0.994	0.005
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.000	0.995	0.005
O70.0 First degree perineal laceration during delivery	0.000	0.995	0.005
K65.0 Acute peritonitis	0.000	0.995	0.005
X51.9 Unspecified place	0.005	0.995	0.000
K71.0 Toxic liver disease with cholestasis	0.005	0.995	0.000
I05-I09 Chronic rheumatic heart diseases	0.000	0.995	0.005
K75.9 Inflammatory liver disease, unspecified	0.005	0.995	0.000
C92.1 Chronic myeloid leukaemia	0.005	0.995	0.000
K74.4 Secondary biliary cirrhosis	0.005	0.995	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.005	0.995	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.995	0.005
N75.8 Other diseases of Bartholin's gland	0.005	0.995	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.005	0.995	0.000
M05.1 Rheumatoid lung disease	0.000	0.995	0.005
K71.9 Toxic liver disease, unspecified	0.005	0.995	0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.000	0.995	0.005
L03.0 Cellulitis of finger and toe	0.000	0.995	0.005
K71.8 Toxic liver disease with other disorders of liver	0.005	0.995	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.005	0.995	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.005	0.995	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.005	0.995	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.005	0.995	0.000
K71.2 Toxic liver disease with acute hepatitis	0.005	0.995	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.004	0.995	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.995	0.004
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.995	0.004
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.995	0.004
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.995	0.004
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.995	0.004
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.995	0.004
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.995	0.004
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.995	0.004
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.995	0.004
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.000	0.995	0.005
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.995	0.005
Q61.3 Polycystic kidney, unspecified	0.000	0.995	0.005
Q61.2 Polycystic kidney, adult type	0.000	0.995	0.005
Z02.9 Examination for administrative purposes, unspecified	0.004	0.995	0.000
Z02.7 Issue of medical certificate	0.004	0.995	0.000
Z02.6 Examination for insurance purposes	0.004	0.995	0.000
Z02.5 Examination for participation in sport	0.004	0.995	0.000
Z02.4 Examination for driving licence	0.004	0.995	0.000
Z02.3 Examination for recruitment to armed forces	0.004	0.995	0.000
Z02.2 Examination for admission to residential institution	0.004	0.995	0.000
Z02.1 Pre-employment examination	0.004	0.995	0.000
Z02.0 Examination for admission to educational institution	0.004	0.995	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.995	0.005
L03 Cellulitis	0.000	0.995	0.005
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.000	0.995	0.005
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.000	0.996	0.004
K77.8 Liver disorders in other diseases classified elsewhere	0.004	0.996	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.996	0.004
D33.3 Cranial nerves	0.004	0.996	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
M05.28 Rheumatoid vasculitis (Other)	0.000	0.996	0.004
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.996	0.004
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.996	0.004
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.996	0.004
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.996	0.004
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.996	0.004
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.996	0.004
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.996	0.004
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.996	0.004
K52 Other non-infective gastro-enteritis and colitis	0.000	0.996	0.004
M05.09 Felty's syndrome (Site unspecified)	0.000	0.996	0.004
M05.08 Felty's syndrome (Other)	0.000	0.996	0.004
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.996	0.004
M05.06 Felty's syndrome (Lower leg)	0.000	0.996	0.004
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.996	0.004
M05.04 Felty's syndrome (Hand)	0.000	0.996	0.004
M05.03 Felty's syndrome (Forearm)	0.000	0.996	0.004
M05.02 Felty's syndrome (Upper arm)	0.000	0.996	0.004
M05.01 Felty's syndrome (Shoulder region)	0.000	0.996	0.004
M05.00 Felty's syndrome (Multiple sites)	0.000	0.996	0.004
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.996	0.004
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.996	0.004
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.996	0.004
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.996	0.004
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.996	0.004
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.996	0.004
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.996	0.004
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.996	0.004
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.996	0.004
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.996	0.004
K72.0 Acute and subacute hepatic failure	0.004	0.996	0.000
H61.2 Impacted cerumen	0.000	0.996	0.004
I09 Other rheumatic heart diseases	0.000	0.996	0.004
S42.0 Fracture of clavicle	0.004	0.996	0.000
X51 Travel and motion	0.004	0.996	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.996	0.004
I05 Rheumatic mitral valve diseases	0.000	0.996	0.004
L03.3 Cellulitis of trunk	0.000	0.996	0.004
C92 Myeloid leukaemia	0.004	0.996	0.000
D33.2 Brain, unspecified	0.004	0.996	0.000
Q61 Cystic kidney disease	0.000	0.996	0.004
M05.18 Rheumatoid lung disease (Other)	0.000	0.996	0.004
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.996	0.004
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.996	0.004
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.996	0.004
M05.14 Rheumatoid lung disease (Hand)	0.000	0.996	0.004
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.996	0.004
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.996	0.004
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.996	0.004
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.996	0.004
H35.9 Retinal disorder, unspecified	0.000	0.996	0.004
S91.3 Open wound of other parts of foot	0.000	0.996	0.004
I05.9 Mitral valve disease, unspecified	0.000	0.996	0.004
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.996	0.004
I06 Rheumatic aortic valve diseases	0.000	0.996	0.004
S30.2 Contusion of external genital organs	0.000	0.996	0.004
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.000	0.996	0.004
C92.9 Myeloid leukaemia, unspecified	0.003	0.996	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.996	0.003
K52.3 Indeterminate colitis	0.000	0.996	0.003
S92.50 Fracture of other toe (closed)	0.000	0.997	0.003
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.997	0.003
D33 Benign neoplasm of brain and other parts of central nervous system	0.003	0.997	0.000
N88.2 Stricture and stenosis of cervix uteri	0.000	0.997	0.003
C92.7 Other myeloid leukaemia	0.003	0.997	0.000
C92.5 Acute myelomonocytic leukaemia	0.003	0.997	0.000
S42.01 Fracture of clavicle (open)	0.003	0.997	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.997	0.003
K52.1 Toxic gastro-enteritis and colitis	0.000	0.997	0.003
Q61.9 Cystic kidney disease, unspecified	0.000	0.997	0.003
X51.8 Other specified place	0.003	0.997	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.997	0.003
I09.8 Other specified rheumatic heart diseases	0.000	0.997	0.003
I09.2 Chronic rheumatic pericarditis	0.000	0.997	0.003
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.997	0.003
I09.0 Rheumatic myocarditis	0.000	0.997	0.003
X51.1 Residential institution	0.003	0.997	0.000
S92.5 Fracture of other toe	0.000	0.997	0.003
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.997	0.003
X51.7 Farm	0.003	0.997	0.000
X51.6 Industrial and construction area	0.003	0.997	0.000
X51.5 Trade and service area	0.003	0.997	0.000
X51.4 Street and highway	0.003	0.997	0.000
X51.3 Sports and athletics area	0.003	0.997	0.000
X51.2 School, other institution and public administrative area	0.003	0.997	0.000
X51.0 Home	0.003	0.997	0.000
I05.8 Other mitral valve diseases	0.000	0.997	0.003
I07.9 Tricuspid valve disease, unspecified	0.000	0.997	0.003
I07.8 Other tricuspid valve diseases	0.000	0.997	0.003
I07.2 Tricuspid stenosis with insufficiency	0.000	0.997	0.003
I07.0 Tricuspid stenosis	0.000	0.997	0.003
I09.9 Rheumatic heart disease, unspecified	0.000	0.997	0.003
M79.65 Pain in limb (Pelvic region and thigh)	0.000	0.997	0.003
H35.6 Retinal haemorrhage	0.001	0.997	0.002
C92.0 Acute myeloid leukaemia	0.003	0.997	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.003	0.997	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.003	0.997	0.000
C92.3 Myeloid sarcoma	0.003	0.997	0.000
C92.2 Subacute myeloid leukaemia	0.003	0.997	0.000
I06.0 Rheumatic aortic stenosis	0.000	0.997	0.003
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.000	0.997	0.003
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.000	0.997	0.003
C92.4 Acute promyelocytic leukaemia	0.003	0.997	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.000	0.997	0.003
I05.2 Mitral stenosis with insufficiency	0.000	0.997	0.003
Q61.8 Other cystic kidney diseases	0.000	0.997	0.003
Q61.5 Medullary cystic kidney	0.000	0.997	0.003
Q61.1 Polycystic kidney, infantile type	0.000	0.997	0.003
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.003	0.997	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.997	0.003
S92.3 Fracture of metatarsal bone	0.000	0.997	0.003
I05.1 Rheumatic mitral insufficiency	0.000	0.997	0.003
I06.8 Other rheumatic aortic valve diseases	0.000	0.997	0.003
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.997	0.003
L03.8 Cellulitis of other sites	0.000	0.997	0.003
Q61.4 Renal dysplasia	0.000	0.997	0.003
S92.4 Fracture of great toe	0.000	0.997	0.003
X50.2 School, other institution and public administrative area	0.003	0.997	0.000
I07.1 Tricuspid insufficiency	0.000	0.997	0.003
D33.0 Brain, supratentorial	0.003	0.997	0.000
S92.41 Fracture of great toe (open)	0.000	0.997	0.003
S92.51 Fracture of other toe (open)	0.000	0.997	0.003
X50 Overexertion and strenuous or repetitive movements	0.003	0.997	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.000	0.997	0.003
L03.9 Cellulitis, unspecified	0.000	0.997	0.003
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.000	0.997	0.003
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.000	0.997	0.003
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.000	0.997	0.003
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.000	0.997	0.003
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.000	0.997	0.003
S92.40 Fracture of great toe (closed)	0.000	0.997	0.003
D33.9 Central nervous system, unspecified	0.003	0.997	0.000
D33.7 Other specified parts of central nervous system	0.003	0.997	0.000
D33.1 Brain, infratentorial	0.003	0.997	0.000
I86.8 Varicose veins of other specified sites	0.000	0.997	0.003
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
S92 Fracture of foot, except ankle	0.000	0.997	0.003
D33.4 Spinal cord	0.003	0.997	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.997	0.002
H53.8 Other visual disturbances	0.003	0.997	0.000
I06.1 Rheumatic aortic insufficiency	0.000	0.997	0.002
X50-X57 Overexertion, travel and privation	0.003	0.997	0.000
O63.9 Long labour, unspecified	0.003	0.997	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.000	0.997	0.003
E80.4 Gilbert's syndrome	0.000	0.997	0.002
X50.4 Street and highway	0.002	0.998	0.000
L57.3 Poikiloderma of Civatte	0.000	0.998	0.002
L57.2 Cutis rhomboidalis nuchae	0.000	0.998	0.002
L57.1 Actinic reticuloid	0.000	0.998	0.002
L57.5 Actinic granuloma	0.000	0.998	0.002
S92.31 Fracture of metatarsal bone (open)	0.000	0.998	0.002
M19.04 Primary arthrosis of other joints (Hand)	0.002	0.998	0.000
H35.8 Other specified retinal disorders	0.000	0.998	0.002
S92.9 Fracture of foot, unspecified	0.000	0.998	0.002
S92.2 Fracture of other tarsal bone(s)	0.000	0.998	0.002
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.000	0.998	0.002
X50.9 Unspecified place	0.002	0.998	0.000
X50.8 Other specified place	0.002	0.998	0.000
X50.5 Trade and service area	0.002	0.998	0.000
X50.3 Sports and athletics area	0.002	0.998	0.000
X50.0 Home	0.002	0.998	0.000
X50.7 Farm	0.002	0.998	0.000
X50.1 Residential institution	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
X50.6 Industrial and construction area	0.002	0.998	0.000
X57 Unspecified privation	0.002	0.998	0.000
X54 Lack of water	0.002	0.998	0.000
X53 Lack of food	0.002	0.998	0.000
X52 Prolonged stay in weightless environment	0.002	0.998	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.998	0.002
T87.4 Infection of amputation stump	0.000	0.998	0.002
D36.1 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.002	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.000	0.998	0.002
I42.6 Alcoholic cardiomyopathy	0.002	0.998	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.998	0.002
S92.90 Fracture of foot, unspecified (closed)	0.000	0.998	0.002
S92.1 Fracture of talus	0.000	0.998	0.002
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.000	0.998	0.002
H59.8 Other postprocedural disorders of eye and adnexa	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.998	0.002
S92.91 Fracture of foot, unspecified (open)	0.000	0.998	0.002
C53.9 Cervix uteri, unspecified	0.000	0.998	0.002
X50.09 Overexertion and strenuous or repetitive movements; Home; During unspecified activity	0.002	0.998	0.000
X50.04 Overexertion and strenuous or repetitive movements; Home; While resting, sleeping, eating or engaging in other vital activities	0.002	0.998	0.000
X50.30 Overexertion and strenuous or repetitive movements; Sports and athletics area;While engaged in sports activity	0.002	0.998	0.000
X50.52 Overexertion and strenuous or repetitive movements, Trade and service area, While working for income	0.002	0.998	0.000
X50.89 Overexertion and strenuous or repetitive movements: Other specified places: During unspecified activity	0.002	0.998	0.000
X50.82 Overexertion and strenuous or repetitive movements; Other specified places ;While working for income	0.002	0.998	0.000
X50.99 Overexertion and strenuous or repetitive movements; Unspecified place ;During unspecified activity	0.002	0.998	0.000
X50.90 Overexertion and strenuous or repetitive movements: Unspecified place: While engaged in sports activity	0.002	0.998	0.000
Z81.8 Family history of other mental and behavioural disorders	0.000	0.998	0.002
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
H81.1 Benign paroxysmal vertigo	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.000	0.998	0.002
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
I49.3 Ventricular premature depolarisation	0.000	0.998	0.002
L57.4 Cutis laxa senilis	0.000	0.998	0.002
X52.9 Unspecified place	0.002	0.998	0.000
X52.8 Other specified place	0.002	0.998	0.000
X52.7 Farm	0.002	0.998	0.000
X52.6 Industrial and construction area	0.002	0.998	0.000
X52.5 Trade and service area	0.002	0.998	0.000
X52.4 Street and highway	0.002	0.998	0.000
X52.3 Sports and athletics area	0.002	0.998	0.000
X52.2 School, other institution and public administrative area	0.002	0.998	0.000
X52.1 Residential institution	0.002	0.998	0.000
X52.0 Home	0.002	0.998	0.000
X53.9 Unspecified place	0.002	0.998	0.000
X53.8 Other specified place	0.002	0.998	0.000
X53.7 Farm	0.002	0.998	0.000
X53.6 Industrial and construction area	0.002	0.998	0.000
X53.5 Trade and service area	0.002	0.998	0.000
X53.4 Street and highway	0.002	0.998	0.000
X53.3 Sports and athletics area	0.002	0.998	0.000
X53.2 School, other institution and public administrative area	0.002	0.998	0.000
X53.1 Residential institution	0.002	0.998	0.000
X53.0 Home	0.002	0.998	0.000
X54.9 Unspecified place	0.002	0.998	0.000
X54.8 Other specified place	0.002	0.998	0.000
X54.7 Farm	0.002	0.998	0.000
X54.6 Industrial and construction area	0.002	0.998	0.000
X54.5 Trade and service area	0.002	0.998	0.000
X54.4 Street and highway	0.002	0.998	0.000
X54.3 Sports and athletics area	0.002	0.998	0.000
X54.2 School, other institution and public administrative area	0.002	0.998	0.000
X54.1 Residential institution	0.002	0.998	0.000
X54.0 Home	0.002	0.998	0.000
X57.9 Unspecified place	0.002	0.998	0.000
X57.8 Other specified place	0.002	0.998	0.000
X57.7 Farm	0.002	0.998	0.000
X57.6 Industrial and construction area	0.002	0.998	0.000
X57.5 Trade and service area	0.002	0.998	0.000
X57.4 Street and highway	0.002	0.998	0.000
X57.3 Sports and athletics area	0.002	0.998	0.000
X57.2 School, other institution and public administrative area	0.002	0.998	0.000
X57.1 Residential institution	0.002	0.998	0.000
X57.0 Home	0.002	0.998	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.002	0.998	0.000
J95.8 Other postprocedural respiratory disorders	0.002	0.998	0.000
Z49.0 Preparatory care for dialysis	0.000	0.998	0.002
K65 Peritonitis	0.000	0.998	0.002
G95.1 Vascular myelopathies	0.002	0.998	0.000
D86 Sarcoidosis	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
S92.11 Fracture of talus (open)	0.000	0.998	0.001
I05.0 Mitral stenosis	0.000	0.998	0.001
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
S91 Open wound of ankle and foot	0.000	0.998	0.002
S92.71 Multiple fractures of foot (open)	0.000	0.998	0.001
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
R00.0 Tachycardia, unspecified	0.000	0.998	0.002
I42 Cardiomyopathy	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.000	0.998	0.002
Q64.7 Other congenital malformations of bladder and urethra	0.000	0.998	0.002
A49.8 Other bacterial infections of unspecified site	0.002	0.998	0.000
I42.0 Dilated cardiomyopathy	0.002	0.998	0.000
Q64.4 Malformation of urachus	0.000	0.998	0.001
Q64.9 Congenital malformation of urinary system, unspecified	0.000	0.998	0.001
Q64.8 Other specified congenital malformations of urinary system	0.000	0.998	0.001
Q64.6 Congenital diverticulum of bladder	0.000	0.998	0.001
Q64.5 Congenital absence of bladder and urethra	0.000	0.998	0.001
Q64.2 Congenital posterior urethral valves	0.000	0.998	0.001
Q64.1 Exstrophy of urinary bladder	0.000	0.998	0.001
Q64.0 Epispadias	0.000	0.998	0.001
Q61.0 Congenital single renal cyst	0.000	0.998	0.001
S92.0 Fracture of calcaneus	0.000	0.998	0.002
T50.8 Diagnostic agents	0.000	0.998	0.002
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.998	0.002
K74.6 Other and unspecified cirrhosis of liver	0.000	0.998	0.001
S59.9 Unspecified injury of forearm	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.998	0.001
Z93.0 Tracheostomy status	0.000	0.998	0.002
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
H21.0 Hyphaema	0.000	0.998	0.001
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.998	0.001
I42.7 Cardiomyopathy due to drugs and other external agents	0.001	0.998	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.002	0.998	0.000
I49.5 Sick sinus syndrome	0.000	0.998	0.002
H50.1 Divergent concomitant strabismus	0.000	0.998	0.002
I49.4 Other and unspecified premature depolarisation	0.000	0.998	0.002
T92.1 Sequelae of fracture of arm	0.002	0.998	0.000
M76.86 Other enthesopathies of lower limb, excluding foot (Lower leg)	0.001	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.998	0.001
S91.2 Open wound of toe(s) with damage to nail	0.000	0.998	0.001
F23.9 Acute and transient psychotic disorder, unspecified	0.001	0.999	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.001	0.999	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.000	0.999	0.001
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.999	0.001
I42.9 Cardiomyopathy, unspecified	0.001	0.999	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.999	0.001
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.999	0.001
S92.10 Fracture of talus (closed)	0.000	0.999	0.001
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.999	0.001
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.999	0.001
G82.1 Spastic paraplegia	0.001	0.999	0.000
I42.4 Endocardial fibroelastosis	0.001	0.999	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.001	0.999	0.000
S92.70 Multiple fractures of foot (closed)	0.000	0.999	0.001
H21.1 Other vascular disorders of iris and ciliary body	0.000	0.999	0.001
Q62.5 Duplication of ureter	0.000	0.999	0.001
S92.01 Fracture of calcaneus (open)	0.000	0.999	0.001
D86.1 Sarcoidosis of lymph nodes	0.001	0.999	0.000
H57.1 Ocular pain	0.000	0.999	0.001
I42.5 Other restrictive cardiomyopathy	0.001	0.999	0.000
I86.4 Gastric varices	0.000	0.999	0.001
H50.2 Vertical strabismus	0.000	0.999	0.001
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.001	0.999	0.000
Q60.2 Renal agenesis, unspecified	0.000	0.999	0.001
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.000	0.999	0.001
T50.7 Analeptics and opioid receptor antagonists	0.000	0.999	0.001
T50.5 Appetite depressants	0.000	0.999	0.001
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.999	0.001
T50.0 Mineralocorticoids and their antagonists	0.000	0.999	0.001
Q60 Renal agenesis and other reduction defects of kidney	0.000	0.999	0.001
Y86 Sequelae of other accidents	0.001	0.999	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.999	0.001
J38.4 Oedema of larynx	0.001	0.999	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.000	0.999	0.001
R27.8 Other and unspecified lack of coordination	0.000	0.999	0.001
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.999	0.001
W25.9 Unspecified place	0.001	0.999	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.999	0.001
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.000	0.999	0.001
D86.0 Sarcoidosis of lung	0.001	0.999	0.000
M24.1 Other articular cartilage disorders	0.000	0.999	0.001
V80.9 Rider or occupant injured in other and unspecified transport accidents	0.001	0.999	0.000
I15.9 Seconday hypertension, unspecified	0.000	0.999	0.001
Q62.7 Congenital vesico-uretero-renal reflux	0.000	0.999	0.001
Q62.6 Malposition of ureter	0.000	0.999	0.001
Q62.4 Agenesis of ureter	0.000	0.999	0.001
Q62.2 Congenital megaloureter	0.000	0.999	0.001
Q62.0 Congenital hydronephrosis	0.000	0.999	0.001
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.999	0.001
H21 Other disorders of iris and ciliary body	0.000	0.999	0.001
I49 Other cardiac arrhythmias	0.000	0.999	0.001
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.999	0.001
D86.3 Sarcoidosis of skin	0.001	0.999	0.000
I42.8 Other cardiomyopathies	0.001	0.999	0.000
I65.1 Occlusion and stenosis of basilar artery	0.001	0.999	0.000
K65.8 Other peritonitis	0.000	0.999	0.001
N89.6 Tight hymenal ring	0.001	0.999	0.000
S03.2 Dislocation of tooth	0.001	0.999	0.000
S91.0 Open wound of ankle	0.000	0.999	0.001
M19.01 Primary arthrosis of other joints (Shoulder region)	0.001	0.999	0.000
C79.2 Secondary malignant neoplasm of skin	0.001	0.999	0.000
I42.2 Other hypertrophic cardiomyopathy	0.001	0.999	0.000
I49.9 Cardiac arrhythmia, unspecified	0.000	0.999	0.001
T50.1 Loop [high-ceiling] diuretics	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations