TreeWAS – Variant ID: rs4959094

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
J45.9 Asthma, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
M35.3 Polymyalgia rheumatica	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
G35 Multiple sclerosis	0.000	0.000	1.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	1.000	0.000	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	1.000	0.000	0.000
M45 Ankylosing spondylitis	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
J33 Nasal polyp	1.000	0.000	0.000
J33.0 Polyp of nasal cavity	1.000	0.000	0.000
J33.9 Nasal polyp, unspecified	1.000	0.000	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M45-M49 Spondylopathies	1.000	0.000	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
M06.3 Rheumatoid nodule	0.999	0.001	0.000
E10.1 With ketoacidosis	0.998	0.002	0.000
M20 Acquired deformities of fingers and toes	0.996	0.004	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.994	0.006	0.000
E10-E14 Diabetes mellitus	0.990	0.010	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.989	0.011	0.000
M31 Other necrotising vasculopathies	0.989	0.011	0.000
M06.34 Rheumatoid nodule (Hand)	0.988	0.012	0.000
R31 Unspecified haematuria	0.987	0.013	0.000
E14 Unspecified diabetes mellitus	0.985	0.015	0.000
M06.4 Inflammatory polyarthropathy	0.982	0.018	0.000
M65-M68 Disorders of synovium and tendon	0.982	0.018	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.975	0.025	0.000
M06.0 Seronegative rheumatoid arthritis	0.975	0.025	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.968	0.032	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.967	0.033	0.000
E14.9 Without complications	0.966	0.034	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.955	0.045	0.000
M65 Synovitis and tenosynovitis	0.954	0.046	0.000
M31.6 Other giant cell arteritis	0.948	0.052	0.000
E10.4 With neurological complications	0.946	0.054	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.940	0.060	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.934	0.066	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.929	0.071	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.929	0.071	0.000
E10.5 With peripheral circulatory complications	0.929	0.071	0.000
E14.3 With ophthalmic complications	0.926	0.074	0.000
J33.8 Other polyp of sinus	0.921	0.079	0.000
M30 Polyarteritis nodosa and related conditions	0.919	0.081	0.000
M34 Systemic sclerosis	0.916	0.084	0.000
M20.4 Other hammer toe(s) (acquired)	0.915	0.085	0.000
E10.0 With coma	0.914	0.086	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.910	0.090	0.000
E03 Other hypothyroidism	0.910	0.090	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.894	0.106	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.894	0.106	0.000
M12 Other specific arthropathies	0.887	0.113	0.000
M35.1 Other overlap syndromes	0.881	0.119	0.000
E00-E07 Disorders of thyroid gland	0.876	0.124	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.874	0.126	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.873	0.127	0.000
M07 Psoriatic and enteropathic arthropathies	0.860	0.140	0.000
M05.8 Other seropositive rheumatoid arthritis	0.858	0.142	0.000
J33.1 Polypoid sinus degeneration	0.856	0.144	0.000
E14.6 With other specified complications	0.855	0.145	0.000
M31.3 Wegener's granulomatosis	0.854	0.146	0.000
M49 Spondylopathies in diseases classified elsewhere	0.853	0.147	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.851	0.149	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.851	0.149	0.000
E10.6 With other specified complications	0.850	0.150	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.848	0.152	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.848	0.152	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.847	0.153	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.843	0.157	0.000
E10.8 With unspecified complications	0.837	0.163	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.164	0.836
K90 Intestinal malabsorption	0.000	0.172	0.828
M31.7 Microscopic polyangiitis	0.820	0.180	0.000
M66 Spontaneous rupture of synovium and tendon	0.815	0.185	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.813	0.187	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.809	0.191	0.000
E10.2 With renal complications	0.808	0.192	0.000
M08 Juvenile arthritis	0.807	0.193	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.807	0.193	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.196	0.804
E06 Thyroiditis	0.803	0.197	0.000
M20.1 Hallux valgus (acquired)	0.803	0.197	0.000
M05.2 Rheumatoid vasculitis	0.800	0.200	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.797	0.203	0.000
M34.1 CR(E)ST syndrome	0.794	0.206	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.790	0.209	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.789	0.211	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.786	0.214	0.000
M12.3 Palindromic rheumatism	0.781	0.219	0.000
M30.0 Polyarteritis nodosa	0.781	0.219	0.000
M05.1 Rheumatoid lung disease	0.778	0.222	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.770	0.230	0.000
M67 Other disorders of synovium and tendon	0.768	0.232	0.000
M34.9 Systemic sclerosis, unspecified	0.766	0.234	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.234	0.766
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.764	0.236	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.763	0.237	0.000
M91-M94 Chondropathies	0.762	0.238	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.762	0.238	0.000
M07.3 Other psoriatic arthropathies	0.759	0.241	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.754	0.246	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.248	0.752
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.750	0.250	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.748	0.252	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.746	0.254	0.000
M00-M03 Infectious arthropathies	0.742	0.257	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.740	0.260	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.730	0.269	0.000
M35.2 Behcet's disease	0.730	0.270	0.000
E16 Other disorders of pancreatic internal secretion	0.729	0.271	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.724	0.276	0.000
M35.8 Other specified systemic involvement of connective tissue	0.723	0.276	0.000
E14.1 With ketoacidosis	0.723	0.277	0.000
E14.2 Withrenal complications	0.721	0.279	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.718	0.282	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.717	0.283	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.717	0.283	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.717	0.283	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.717	0.283	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.717	0.283	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.716	0.284	0.000
M06.38 Rheumatoid nodule (Other)	0.716	0.284	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.716	0.284	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.716	0.284	0.000
M06.33 Rheumatoid nodule (Forearm)	0.716	0.284	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.716	0.284	0.000
K90.8 Other intestinal malabsorption	0.000	0.285	0.715
J45 Asthma	0.713	0.287	0.000
E03.8 Other specified hypothyroidism	0.712	0.288	0.000
E12 Malnutrition-related diabetes mellitus	0.710	0.290	0.000
M31.2 Lethal midline granuloma	0.709	0.291	0.000
M31.0 Hypersensitivity angiitis	0.709	0.291	0.000
M20.3 Other deformity of hallux (acquired)	0.709	0.291	0.000
M06.8 Other specified rheumatoid arthritis	0.709	0.291	0.000
M14 Arthropathies in other diseases classified elsewhere	0.707	0.293	0.000
M65.2 Calcific tendinitis	0.707	0.293	0.000
M66.2 Spontaneous rupture of extensor tendons	0.707	0.293	0.000
E14.7 With multiple complications	0.706	0.294	0.000
E14.0 With coma	0.706	0.294	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.704	0.296	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.704	0.296	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.704	0.296	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.704	0.296	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.704	0.296	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.704	0.296	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.704	0.296	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.704	0.296	0.000
E10.7 With multiple complications	0.701	0.299	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.699	0.301	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.699	0.301	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.699	0.301	0.000
M34.8 Other forms of systemic sclerosis	0.698	0.302	0.000
E06.1 Subacute thyroiditis	0.697	0.303	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.695	0.305	0.000
M67.8 Other specified disorders of synovium and tendon	0.694	0.306	0.000
M31.1 Thrombotic microangiopathy	0.692	0.307	0.000
M31.8 Other specified necrotising vasculopathies	0.690	0.310	0.000
M65.1 Other infective (teno)synovitis	0.690	0.310	0.000
M20.0 Deformity of finger(s)	0.688	0.312	0.000
M94 Other disorders of cartilage	0.686	0.314	0.000
M65.0 Abscess of tendon sheath	0.684	0.316	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.319	0.681
M12.2 Villonodular synovitis (pigmented)	0.678	0.321	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.678	0.322	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.678	0.322	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.676	0.324	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.674	0.326	0.000
E16.2 Hypoglycaemia, unspecified	0.670	0.330	0.000
M08.0 Juvenile rheumatoid arthritis	0.669	0.331	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.666	0.334	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.666	0.334	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.666	0.334	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.666	0.334	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.666	0.334	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.666	0.334	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.666	0.334	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.666	0.334	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.666	0.334	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.659	0.341	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.659	0.341	0.000
M30.2 Juvenile polyarteritis	0.659	0.341	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.657	0.343	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.657	0.343	0.000
M34.0 Progressive systemic sclerosis	0.657	0.343	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.655	0.344	0.000
M12.5 Traumatic arthropathy	0.655	0.345	0.000
E03.5 Myxoedema coma	0.652	0.347	0.000
E03.4 Atrophy of thyroid (acquired)	0.652	0.347	0.000
E03.3 Postinfectious hypothyroidism	0.652	0.347	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.650	0.350	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.647	0.353	0.000
E03.1 Congenital hypothyroidism without goitre	0.647	0.353	0.000
E06.3 Autoimmune thyroiditis	0.639	0.361	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.636	0.364	0.000
M12.4 Intermittent hydrarthrosis	0.636	0.364	0.000
M12.1 Kaschin-Beck disease	0.636	0.364	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.636	0.364	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.634	0.366	0.000
J30-J39 Other diseases of upper respiratory tract	0.634	0.366	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.628	0.372	0.000
E00 Congenital iodine-deficiency syndrome	0.628	0.372	0.000
M60-M63 Disorders of muscles	0.628	0.372	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.621	0.379	0.000
M94.8 Other specified disorders of cartilage	0.620	0.380	0.000
J40-J47 Chronic lower respiratory diseases	0.619	0.381	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.619	0.381	0.000
E14.4 With neurological complications	0.619	0.381	0.000
M12.30 Palindromic rheumatism (Multiple sites)	0.619	0.381	0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.618	0.382	0.000
E06.5 Other chronic thyroiditis	0.617	0.383	0.000
M07.6 Other enteropathic arthropathies	0.616	0.384	0.000
M07.5 Arthropathy in ulcerative colitis	0.616	0.384	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.616	0.384	0.000
M07.2 Psoriatic spondylitis	0.616	0.384	0.000
M07.1 Arthritis mutilans	0.616	0.384	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.616	0.384	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.615	0.385	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.615	0.385	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.615	0.385	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.615	0.385	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.615	0.385	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.615	0.385	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.615	0.385	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.615	0.385	0.000
E06.9 Thyroiditis, unspecified	0.615	0.385	0.000
E14.5 With peripheral circulatory complications	0.613	0.387	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.612	0.388	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.611	0.388	0.000
M49.4 Neuropathic spondylopathy	0.611	0.388	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.611	0.388	0.000
M49.2 Enterobacterial spondylitis	0.611	0.388	0.000
M49.1 Brucella spondylitis	0.611	0.388	0.000
M49.0 Tuberculosis of spine	0.611	0.388	0.000
Chapter X Diseases of the respiratory system	0.611	0.389	0.000
E14.8 With unspecified complications	0.609	0.390	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.608	0.392	0.000
M35.7 Hypermobility syndrome	0.608	0.392	0.000
G36 Other acute disseminated demyelination	0.000	0.402	0.598
M02 Reactive arthropathies	0.596	0.404	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.406	0.594
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.406	0.594
K90.1 Tropical sprue	0.000	0.406	0.594
M86-M90 Other osteopathies	0.592	0.408	0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.591	0.409	0.000
M31.9 Necrotising vasculopathy, unspecified	0.589	0.410	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.589	0.411	0.000
M66.1 Rupture of synovium	0.584	0.416	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.418	0.582
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.581	0.419	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.580	0.419	0.000
J20-J22 Other acute lower respiratory infections	0.580	0.420	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.579	0.421	0.000
M08.9 Juvenile arthritis, unspecified	0.579	0.421	0.000
M08.8 Other juvenile arthritis	0.579	0.421	0.000
M08.4 Pauciarticular juvenile arthritis	0.579	0.421	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.579	0.421	0.000
M08.2 Juvenile arthritis with systemic onset	0.579	0.421	0.000
M08.1 Juvenile ankylosing spondylitis	0.579	0.421	0.000
J32 Chronic sinusitis	0.578	0.422	0.000
E13 Other specified diabetes mellitus	0.577	0.423	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.424	0.576
G37.4 Subacute necrotising myelitis	0.000	0.424	0.576
G37.2 Central pontine myelinolysis	0.000	0.424	0.576
G37.1 Central demyelination of corpus callosum	0.000	0.424	0.576
G37.0 Diffuse sclerosis	0.000	0.424	0.576
E06.4 Drug-induced thyroiditis	0.576	0.424	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.576	0.424	0.000
E06.0 Acute thyroiditis	0.576	0.424	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.574	0.426	0.000
M67.4 Ganglion	0.574	0.426	0.000
M05.28 Rheumatoid vasculitis (Other)	0.573	0.427	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.573	0.427	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.573	0.427	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.573	0.427	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.573	0.427	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.573	0.427	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.573	0.427	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.573	0.427	0.000
M65.3 Trigger finger	0.573	0.427	0.000
M66.4 Spontaneous rupture of other tendons	0.573	0.427	0.000
E15 Nondiabetic hypoglycaemic coma	0.566	0.434	0.000
M46 Other inflammatory spondylopathies	0.566	0.434	0.000
M12.38 Palindromic rheumatism (Other)	0.560	0.440	0.000
M12.37 Palindromic rheumatism (Ankle and foot)	0.560	0.440	0.000
M12.36 Palindromic rheumatism (Lower leg)	0.560	0.440	0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.560	0.440	0.000
M12.34 Palindromic rheumatism (Hand)	0.560	0.440	0.000
M12.33 Palindromic rheumatism (Forearm)	0.560	0.440	0.000
M12.32 Palindromic rheumatism (Upper arm)	0.560	0.440	0.000
M12.31 Palindromic rheumatism (Shoulder region)	0.560	0.440	0.000
M94.88 Other specified disorders of cartilage (Other)	0.560	0.440	0.000
M05.18 Rheumatoid lung disease (Other)	0.558	0.442	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.558	0.442	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.558	0.442	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.558	0.442	0.000
M05.14 Rheumatoid lung disease (Hand)	0.558	0.442	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.558	0.442	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.558	0.442	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.558	0.442	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.558	0.442	0.000
J32.9 Chronic sinusitis, unspecified	0.558	0.442	0.000
M66.0 Rupture of popliteal cyst	0.556	0.443	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.556	0.444	0.000
M66.3 Spontaneous rupture of flexor tendons	0.555	0.445	0.000
J42 Unspecified chronic bronchitis	0.555	0.445	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.554	0.446	0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.551	0.449	0.000
E16.1 Other hypoglycaemia	0.551	0.449	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.551	0.449	0.000
M67.3 Transient synovitis	0.551	0.449	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.549	0.451	0.000
M32 Systemic lupus erythematosus	0.548	0.452	0.000
J22 Unspecified acute lower respiratory infection	0.545	0.455	0.000
M07.38 Other psoriatic arthropathies (Other)	0.544	0.456	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.544	0.456	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.544	0.456	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.544	0.456	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.457	0.543
M12.26 Villonodular synovitis (pigmented) (Lower leg)	0.542	0.458	0.000
J95-J99 Other diseases of the respiratory system	0.541	0.459	0.000
E65-E68 Obesity and other hyperalimentation	0.537	0.463	0.000
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)	0.536	0.464	0.000
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)	0.536	0.464	0.000
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)	0.536	0.464	0.000
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)	0.536	0.464	0.000
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)	0.536	0.464	0.000
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)	0.536	0.464	0.000
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)	0.536	0.464	0.000
M13 Other arthritis	0.535	0.465	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.532	0.467	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.532	0.467	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.531	0.469	0.000
M65.21 Calcific tendinitis (Shoulder region)	0.530	0.470	0.000
M94.9 Disorder of cartilage, unspecified	0.528	0.472	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.523	0.477	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.523	0.477	0.000
E16.4 Abnormal secretion of gastrin	0.523	0.477	0.000
E16.3 Increased secretion of glucagon	0.523	0.477	0.000
M14.6 Neuropathic arthropathy	0.522	0.478	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.517	0.482	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.516	0.484	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.514	0.486	0.000
M06.18 Adult-onset Still's disease (Other)	0.514	0.486	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.514	0.486	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.514	0.486	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.514	0.486	0.000
M06.14 Adult-onset Still's disease (Hand)	0.514	0.486	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.514	0.486	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.514	0.486	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.514	0.486	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.514	0.486	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.514	0.486	0.000
M06.28 Rheumatoid bursitis (Other)	0.514	0.486	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.514	0.486	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.514	0.486	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.514	0.486	0.000
M06.24 Rheumatoid bursitis (Hand)	0.514	0.486	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.514	0.486	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.514	0.486	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.514	0.486	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.514	0.486	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.514	0.486	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.514	0.486	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.514	0.486	0.000
M09.0 Juvenile arthritis in psoriasis	0.514	0.486	0.000
M05.09 Felty's syndrome (Site unspecified)	0.514	0.486	0.000
M05.08 Felty's syndrome (Other)	0.514	0.486	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.514	0.486	0.000
M05.06 Felty's syndrome (Lower leg)	0.514	0.486	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.514	0.486	0.000
M05.04 Felty's syndrome (Hand)	0.514	0.486	0.000
M05.03 Felty's syndrome (Forearm)	0.514	0.486	0.000
M05.02 Felty's syndrome (Upper arm)	0.514	0.486	0.000
M05.01 Felty's syndrome (Shoulder region)	0.514	0.486	0.000
M05.00 Felty's syndrome (Multiple sites)	0.514	0.486	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.514	0.486	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.514	0.486	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.514	0.486	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.514	0.486	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.514	0.486	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.514	0.486	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.514	0.486	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.514	0.486	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.514	0.486	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.514	0.486	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.514	0.486	0.000
M65.8 Other synovitis and tenosynovitis	0.513	0.487	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.512	0.488	0.000
M08.09 Juvenile rheumatoid arthritis (Site unspecified)	0.511	0.489	0.000
E12.9 Without complications	0.509	0.491	0.000
E12.8 With unspecified complications	0.509	0.491	0.000
E12.7 With multiple complications	0.509	0.491	0.000
E12.6 With other specified complications	0.509	0.491	0.000
E12.5 With peripheral circulatory complications	0.509	0.491	0.000
E12.4 With neurological complications	0.509	0.491	0.000
E12.3 With ophthalmic complications	0.509	0.491	0.000
E12.2 With renal complications	0.509	0.491	0.000
E12.1 With ketoacidosis	0.509	0.491	0.000
E12.0 With coma	0.509	0.491	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.508	0.492	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.508	0.492	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.508	0.492	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.508	0.492	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.508	0.492	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.508	0.492	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.508	0.492	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.508	0.492	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.507	0.493	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.507	0.493	0.000
M14.4 Arthropathy in amyloidosis	0.507	0.493	0.000
M14.3 Lipoid dermatoarthritis	0.507	0.493	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.507	0.493	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.507	0.493	0.000
M65.29 Calcific tendinitis (Site unspecified)	0.507	0.493	0.000
M65.28 Calcific tendinitis (Other)	0.507	0.493	0.000
M65.27 Calcific tendinitis (Ankle and foot)	0.507	0.493	0.000
M65.26 Calcific tendinitis (Lower leg)	0.507	0.493	0.000
M65.25 Calcific tendinitis (Pelvic region and thigh)	0.507	0.493	0.000
M65.24 Calcific tendinitis (Hand)	0.507	0.493	0.000
M65.23 Calcific tendinitis (Forearm)	0.507	0.493	0.000
M65.22 Calcific tendinitis (Upper arm)	0.507	0.493	0.000
M65.20 Calcific tendinitis (Multiple sites)	0.507	0.493	0.000
M94.2 Chondromalacia	0.507	0.493	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.507	0.493	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.507	0.493	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.507	0.493	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.507	0.493	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.507	0.493	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.507	0.493	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.507	0.493	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.507	0.493	0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.505	0.495	0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.505	0.495	0.000
M02.3 Reiter's disease	0.503	0.497	0.000
J35 Chronic diseases of tonsils and adenoids	0.503	0.497	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.500	0.499	0.000
M67.0 Short Achilles tendon (acquired)	0.496	0.504	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.496	0.504	0.000
E40-E46 Malnutrition	0.495	0.504	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.495	0.505	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.495	0.505	0.000
M65.19 Other infective (teno)synovitis (Site unspecified)	0.495	0.505	0.000
M65.18 Other infective (teno)synovitis (Other)	0.495	0.505	0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.495	0.505	0.000
M65.16 Other infective (teno)synovitis (Lower leg)	0.495	0.505	0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.495	0.505	0.000
M65.13 Other infective (teno)synovitis (Forearm)	0.495	0.505	0.000
M65.12 Other infective (teno)synovitis (Upper arm)	0.495	0.505	0.000
M65.11 Other infective (teno)synovitis (Shoulder region)	0.495	0.505	0.000
M65.10 Other infective (teno)synovitis (Multiple sites)	0.495	0.505	0.000
K50.1 Crohn's disease of large intestine	0.494	0.506	0.000
M94.3 Chondrolysis	0.492	0.508	0.000
M94.1 Relapsing polychondritis	0.492	0.508	0.000
M67.47 Ganglion, ankle and foot	0.491	0.509	0.000
M65.09 Abscess of tendon sheath (Site unspecified)	0.490	0.509	0.000
M65.08 Abscess of tendon sheath (Other)	0.490	0.509	0.000
M65.07 Abscess of tendon sheath (Ankle and foot)	0.490	0.509	0.000
M65.06 Abscess of tendon sheath (Lower leg)	0.490	0.509	0.000
M65.05 Abscess of tendon sheath (Pelvic region and thigh)	0.490	0.509	0.000
M65.04 Abscess of tendon sheath (Hand)	0.490	0.509	0.000
M65.03 Abscess of tendon sheath (Forearm)	0.490	0.509	0.000
M65.02 Abscess of tendon sheath (Upper arm)	0.490	0.509	0.000
M65.01 Abscess of tendon sheath (Shoulder region)	0.490	0.509	0.000
M65.00 Abscess of tendon sheath (Multiple sites)	0.490	0.509	0.000
M12.57 Traumatic arthropathy (Ankle and foot)	0.489	0.510	0.000
M33 Dermatopolymyositis	0.489	0.511	0.000
J31.2 Chronic pharyngitis	0.487	0.513	0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.486	0.513	0.000
M12.28 Villonodular synovitis (pigmented) (Other)	0.486	0.513	0.000
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.486	0.513	0.000
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.486	0.513	0.000
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.486	0.513	0.000
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.486	0.513	0.000
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.486	0.513	0.000
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.486	0.513	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations