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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs500816
log Bayes Factor = 0.296843
Chromosome 8   position 20,803,103  (GRCh37) Explore rs500816 on Ensembl!
Variant rs500816 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
G93 Other disorders of brain
0.000 0.544 0.456
G82 Paraplegia and tetraplegia
0.000 0.554 0.446
G90-G99 Other disorders of the nervous system
0.000 0.557 0.443
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.557 0.443
G93.1 Anoxic brain damage, not elsewhere classified
0.000 0.560 0.440
G81 Hemiplegia
0.000 0.562 0.438
G93.9 Disorder of brain, unspecified
0.000 0.563 0.437
G95 Other diseases of spinal cord
0.000 0.564 0.436
G95.8 Other specified diseases of spinal cord
0.000 0.567 0.433
G81.9 Hemiplegia, unspecified
0.000 0.569 0.431
G82.2 Paraplegia, unspecified
0.000 0.572 0.428
Chapter VI Diseases of the nervous system
0.000 0.576 0.424
G93.8 Other specified disorders of brain
0.000 0.580 0.420
G93.6 Cerebral oedema
0.000 0.581 0.419
G70-G73 Diseases of myoneural junction and muscle
0.000 0.586 0.414
G82.1 Spastic paraplegia
0.000 0.599 0.401
G95.1 Vascular myelopathies
0.000 0.607 0.393
G72 Other myopathies
0.000 0.616 0.384
G82.5 Tetraplegia, unspecified
0.000 0.620 0.380
G82.4 Spastic tetraplegia
0.000 0.623 0.377
G70 Myasthenia gravis and other myoneural disorders
0.000 0.624 0.376
G93.0 Cerebral cysts
0.000 0.625 0.375
G94 Other disorders of brain in diseases classified elsewhere
0.000 0.626 0.374
G81.1 Spastic hemiplegia
0.000 0.637 0.363
G72.9 Myopathy, unspecified
0.000 0.643 0.357
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.650 0.350
G71 Primary disorders of muscles
0.000 0.657 0.343
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.668 0.332
G96 Other disorders of central nervous system
0.000 0.671 0.329
G93.7 Reye's syndrome
0.000 0.673 0.327
G94.2 Hydrocephalus in other diseases classified elsewhere
0.000 0.676 0.324
G70.9 Myoneural disorder, unspecified
0.000 0.678 0.322
G82.3 Flaccid tetraplegia
0.000 0.680 0.320
G82.0 Flaccid paraplegia
0.000 0.680 0.320
G70.0 Myasthenia gravis
0.000 0.683 0.317
G81.0 Flaccid hemiplegia
0.000 0.686 0.314
G61 Inflammatory polyneuropathy
0.000 0.695 0.304
G92 Toxic encephalopathy
0.000 0.696 0.304
G72.4 Inflammatory myopathy, not elsewhere classified
0.000 0.698 0.302
G62 Other polyneuropathies
0.000 0.698 0.302
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.699 0.301
G93.3 Postviral fatigue syndrome
0.000 0.700 0.300
G72.1 Alcoholic myopathy
0.000 0.706 0.294
G61.8 Other inflammatory polyneuropathies
0.000 0.710 0.290
G90 Disorders of autonomic nervous system
0.000 0.715 0.285
G62.8 Other specified polyneuropathies
0.000 0.717 0.283
G70.8 Other specified myoneural disorders
0.000 0.721 0.279
G95.0 Syringomyelia and syringobulbia
0.000 0.724 0.276
G72.3 Periodic paralysis
0.000 0.725 0.275
G72.2 Myopathy due to other toxic agents
0.000 0.725 0.275
G96.1 Disorders of meninges, not elsewhere classified
0.000 0.725 0.275
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.726 0.274
G71.1 Myotonic disorders
0.000 0.728 0.272
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.729 0.271
G94.1 Hydrocephalus in neoplastic disease
0.000 0.729 0.271
G72.8 Other specified myopathies
0.000 0.729 0.271
G70.2 Congenital and developmental myasthenia
0.000 0.730 0.270
G70.1 Toxic myoneural disorders
0.000 0.730 0.270
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.731 0.269
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.000 0.731 0.268
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.000 0.731 0.268
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.000 0.732 0.268
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.732 0.268
G06.0 Intracranial abscess and granuloma
0.000 0.739 0.261
G06.1 Intraspinal abscess and granuloma
0.000 0.741 0.259
G62.0 Drug-induced polyneuropathy
0.000 0.743 0.257
G03 Meningitis due to other and unspecified causes
0.000 0.745 0.255
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.000 0.746 0.254
G71.0 Muscular dystrophy
0.000 0.746 0.254
G91 Hydrocephalus
0.000 0.747 0.253
G64 Other disorders of peripheral nervous system
0.000 0.749 0.251
G93.2 Benign intracranial hypertension
0.000 0.750 0.250
G93.4 Encephalopathy, unspecified
0.000 0.752 0.248
G72.0 Drug-induced myopathy
0.000 0.753 0.247
G95.9 Disease of spinal cord, unspecified
0.000 0.754 0.246
G71.9 Primary disorder of muscle, unspecified
0.000 0.754 0.246
G71.8 Other primary disorders of muscles
0.000 0.754 0.246
G71.2 Congenital myopathies
0.000 0.754 0.246
G83 Other paralytic syndromes
0.000 0.754 0.246
G96.8 Other specified disorders of central nervous system
0.000 0.759 0.241
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.000 0.762 0.238
G04 Encephalitis, myelitis and encephalomyelitis
0.000 0.773 0.227
G61.9 Inflammatory polyneuropathy, unspecified
0.000 0.778 0.222
G95.2 Cord compression, unspecified
0.000 0.779 0.221
G90.9 Disorder of autonomic nervous system, unspecified
0.000 0.780 0.220
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.780 0.220
G61.1 Serum neuropathy
0.000 0.781 0.218
G96.0 Cerebrospinal fluid leak
0.000 0.782 0.218
G62.2 Polyneuropathy due to other toxic agents
0.000 0.784 0.216
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.000 0.785 0.215
G90.8 Other disorders of autonomic nervous system
0.000 0.789 0.211
G90.2 Horner's syndrome
0.000 0.789 0.211
G03.9 Meningitis, unspecified
0.000 0.790 0.210
G93.5 Compression of brain
0.000 0.791 0.209
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.793 0.207
G96.9 Disorder of central nervous system, unspecified
0.000 0.795 0.205
G90.4 Autonomic dysreflexia
0.000 0.795 0.205
G90.1 Familial dysautonomia [Riley-Day]
0.000 0.795 0.205
G12 Spinal muscular atrophy and related syndromes
0.000 0.795 0.205
G06.2 Extradural and subdural abscess, unspecified
0.000 0.798 0.202
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.800 0.200
G91.9 Hydrocephalus, unspecified
0.000 0.802 0.198
G90.3 Multisystem degeneration
0.000 0.802 0.198
G10 Huntington's disease
0.000 0.802 0.197
G73.7 Myopathy other diseases classified elsewhere
0.000 0.805 0.195
G73.6 Myopathy in metabolic diseases
0.000 0.805 0.195
G73.5 Myopathy in endocrine diseases
0.000 0.805 0.195
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.000 0.805 0.195
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.000 0.805 0.195
G73.2 Other myasthenic syndromes in neoplastic disease
0.000 0.805 0.195
G73.1 Eaton-Lambert syndrome
0.000 0.805 0.195
G60 Hereditary and idiopathic neuropathy
0.000 0.805 0.194
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.000 0.806 0.194
G97.9 Postprocedural disorder of nervous system, unspecified
0.000 0.808 0.192
G97.2 Intracranial hypotension following ventricular shunting
0.000 0.808 0.192
G00 Bacterial meningitis, not elsewhere classified
0.000 0.811 0.189
G80 Infantile cerebral palsy
0.000 0.813 0.187
G97.0 Cerebrospinal fluid leak from spinal puncture
0.000 0.813 0.187
G97.8 Other postprocedural disorders of nervous system
0.000 0.813 0.187
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.000 0.814 0.185
G62.1 Alcoholic polyneuropathy
0.000 0.815 0.185
G91.0 Communicating hydrocephalus
0.000 0.815 0.185
G03.8 Meningitis due to other specified causes
0.000 0.817 0.183
G03.2 Benign recurrent meningitis [Mollaret]
0.000 0.817 0.183
G03.1 Chronic meningitis
0.000 0.817 0.183
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.000 0.818 0.182
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.000 0.818 0.182
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.000 0.818 0.182
G91.3 Posttraumatic hydrocephalus, unspecified
0.000 0.818 0.182
G01 Meningitis in bacterial diseases classified elsewhere
0.000 0.819 0.181
G98 Other disorders of nervous system, not elsewhere classified
0.001 0.820 0.180
G99 Other disorders of nervous system in diseases classified elsewhere
0.000 0.821 0.179
G83.8 Other specified paralytic syndromes
0.000 0.822 0.177
G83.5 Locked-in syndrome
0.000 0.823 0.177
G83.3 Monoplegia, unspecified
0.000 0.823 0.177
G83.0 Diplegia of upper limbs
0.000 0.823 0.177
G91.2 Normal-pressure hydrocephalus
0.000 0.824 0.176
G14 Postpolio syndrome
0.000 0.826 0.173
G83.2 Monoplegia of upper limb
0.000 0.828 0.172
G73.0 Myasthenic syndromes in endocrine diseases
0.000 0.831 0.169
G03.0 Nonpyogenic meningitis
0.000 0.834 0.166
G83.4 Cauda equina syndrome
0.000 0.836 0.164
G04.1 Tropical spastic paraplegia
0.000 0.837 0.163
G04.0 Acute disseminated encephalitis
0.000 0.837 0.163
G11 Hereditary ataxia
0.000 0.838 0.161
G36 Other acute disseminated demyelination
0.000 0.840 0.160
G12.2 Motor neuron disease
0.000 0.841 0.159
G83.9 Paralytic syndrome, unspecified
0.000 0.841 0.158
G97.1 Other reaction to spinal and lumbar puncture
0.000 0.842 0.158
G83.1 Monoplegia of lower limb
0.000 0.844 0.156
G20-G26 Extrapyramidal and movement disorders
0.000 0.845 0.155
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.000 0.849 0.151
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.000 0.851 0.149
G12.9 Spinal muscular atrophy, unspecified
0.000 0.853 0.147
G12.8 Other spinal muscular atrophies and related syndromes
0.000 0.853 0.147
G12.1 Other inherited spinal muscular atrophy
0.000 0.853 0.147
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.000 0.853 0.147
G91.8 Other hydrocephalus
0.000 0.853 0.146
G63.8 Polyneuropathy in other diseases classified elsewhere
0.000 0.856 0.144
G63.6 Polyneuropathy in other musculoskeletal disorders
0.000 0.856 0.144
G63.5 Polyneuropathy in systemic connective tissue disorders
0.000 0.856 0.144
G63.4 Polyneuropathy in nutritional deficiency
0.000 0.856 0.144
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.000 0.856 0.144
G63.1 Polyneuropathy in neoplastic disease
0.000 0.856 0.144
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.000 0.856 0.144
G91.1 Obstructive hydrocephalus
0.000 0.859 0.140
G00.2 Streptococcal meningitis
0.000 0.860 0.140
G60.8 Other hereditary and idiopathic neuropathies
0.000 0.860 0.140
G60.3 Idiopathic progressive neuropathy
0.000 0.860 0.140
G60.2 Neuropathy in association with hereditary ataxia
0.000 0.860 0.140
G60.1 Refsum's disease
0.000 0.860 0.140
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.000 0.860 0.139
G02.1 Meningitis in mycoses
0.000 0.860 0.139
G80.1 Spastic diplegia
0.000 0.861 0.139
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.000 0.862 0.138
G90.0 Idiopathic peripheral autonomic neuropathy
0.000 0.863 0.137
G00.8 Other bacterial meningitis
0.000 0.864 0.136
G00.3 Staphylococcal meningitis
0.000 0.864 0.136
G00.0 Haemophilus meningitis
0.000 0.864 0.136
G30-G32 Other degenerative diseases of the nervous system
0.000 0.864 0.135
G80.4 Ataxic cerebral palsy
0.000 0.865 0.134
G80.3 Dyskinetic cerebral palsy
0.000 0.865 0.134
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.000 0.867 0.133
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.000 0.867 0.133
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.000 0.867 0.133
G80.2 Infantile hemiplegia
0.000 0.867 0.133
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.000 0.868 0.132
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.000 0.872 0.128
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.000 0.872 0.128
G36.0 Neuromyelitis optica [Devic]
0.000 0.873 0.127
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.000 0.873 0.126
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.876 0.124
G11.1 Early-onset cerebellar ataxia
0.000 0.876 0.124
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.000 0.880 0.120
G00.9 Bacterial meningitis, unspecified
0.000 0.881 0.119
G80.0 Spastic cerebral palsy
0.000 0.883 0.116
G11.8 Other hereditary ataxias
0.000 0.884 0.116
G11.3 Cerebellar ataxia with defective DNA repair
0.000 0.884 0.116
G11.2 Late-onset cerebellar ataxia
0.000 0.884 0.116
G11.0 Congenital nonprogressive ataxia
0.000 0.884 0.116
G36.9 Acute disseminated demyelination, unspecified
0.000 0.885 0.115
G36.8 Other specified acute disseminated demyelination
0.000 0.885 0.115
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.885 0.115
G61.0 Guillain-Barre syndrome
0.000 0.888 0.112
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.000 0.889 0.111
G22 Parkinsonism in diseases classified elsewhere
0.000 0.889 0.111
G23 Other degenerative diseases of basal ganglia
0.000 0.889 0.110
G35 Multiple sclerosis
0.000 0.889 0.110
G80.8 Other infantile cerebral palsy
0.000 0.890 0.110
G11.4 Hereditary spastic paraplegia
0.000 0.891 0.109
G25 Other extrapyramidal and movement disorders
0.000 0.895 0.105
G00.1 Pneumococcal meningitis
0.000 0.896 0.104
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.897 0.102
G24 Dystonia
0.000 0.898 0.102
G21 Secondary Parkinsonism
0.000 0.900 0.100
I63.8 Other cerebral infarction
0.000 0.900 0.100
I63 Cerebral infarction
0.000 0.902 0.098
G60.0 Hereditary motor and sensory neuropathy
0.000 0.904 0.096
G02.0 Meningitis in viral diseases classified elsewhere
0.001 0.905 0.095
G25.2 Other specified forms of tremor
0.000 0.906 0.094
G63.2 Diabetic polyneuropathy
0.000 0.907 0.093
G37 Other demyelinating diseases of central nervous system
0.000 0.910 0.090
G80.9 Infantile cerebral palsy, unspecified
0.000 0.912 0.088
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.913 0.087
I69 Sequelae of cerebrovascular disease
0.000 0.913 0.087
G25.0 Essential tremor
0.000 0.914 0.086
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.915 0.085
G24.5 Blepharospasm
0.000 0.916 0.084
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.917 0.083
G11.9 Hereditary ataxia, unspecified
0.000 0.918 0.081
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.919 0.081
G62.9 Polyneuropathy, unspecified
0.000 0.920 0.080
G23.9 Degenerative disease of basal ganglia, unspecified
0.000 0.920 0.079
G23.3 Multiple system atrophy, cerebellar type
0.000 0.920 0.079
G23.2 Striatonigral degeneration
0.000 0.920 0.079
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.000 0.920 0.079
G23.0 Hallervorden-Spatz disease
0.000 0.920 0.079
G23.8 Other specified degenerative diseases of basal ganglia
0.000 0.921 0.079
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.921 0.079
I60-I69 Cerebrovascular diseases
0.000 0.921 0.079
G25.1 Drug-induced tremor
0.000 0.922 0.078
G24.8 Other dystonia
0.000 0.923 0.077
G25.6 Drug-induced tics and other tics of organic origin
0.000 0.924 0.076
G25.4 Drug-induced chorea
0.000 0.924 0.076
G25.5 Other chorea
0.000 0.925 0.075
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.926 0.073
G24.4 Idiopathic orofacial dystonia
0.000 0.927 0.073
G24.2 Idiopathic nonfamilial dystonia
0.000 0.927 0.073
G24.0 Drug-induced dystonia
0.000 0.927 0.073
G21.8 Other secondary Parkinsonism
0.000 0.928 0.072
G21.3 Postencephalitic Parkinsonism
0.000 0.928 0.072
G21.2 Secondary Parkinsonism due to other external agents
0.000 0.928 0.072
G21.4 Vascular parkinsonism
0.000 0.928 0.071
G21.1 Other drug-induced secondary Parkinsonism
0.000 0.929 0.071
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.930 0.070
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.930 0.070
G24.1 Idiopathic familial dystonia
0.000 0.930 0.069
G21.0 Malignant neuroleptic syndrome
0.000 0.931 0.068
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.932 0.068
G21.9 Secondary Parkinsonism, unspecified
0.000 0.935 0.065
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.935 0.065
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.935 0.065
G37.5 Concentric sclerosis [Balo]
0.000 0.935 0.065
G37.4 Subacute necrotising myelitis
0.000 0.935 0.065
G37.2 Central pontine myelinolysis
0.000 0.935 0.065
G37.1 Central demyelination of corpus callosum
0.000 0.935 0.065
G37.0 Diffuse sclerosis
0.000 0.935 0.065
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.935 0.064
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.937 0.063
G25.9 Extrapyramidal and movement disorder, unspecified
0.000 0.939 0.061
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.941 0.059
G24.9 Dystonia, unspecified
0.000 0.941 0.059
G24.3 Spasmodic torticollis
0.000 0.941 0.058
G25.3 Myoclonus
0.000 0.942 0.058
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.944 0.056
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.946 0.054
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.946 0.054
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.947 0.053
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.947 0.053
I60 Subarachnoid haemorrhage
0.000 0.947 0.053
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.950 0.050
I65.1 Occlusion and stenosis of basilar artery
0.000 0.950 0.050
I62 Other nontraumatic intracranial haemorrhage
0.000 0.951 0.049
G30 Alzheimer's disease
0.001 0.952 0.048
I61 Intracerebral haemorrhage
0.000 0.952 0.048
I63.9 Cerebral infarction, unspecified
0.000 0.952 0.048
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.953 0.047
I60.8 Other subarachnoid haemorrhage
0.000 0.954 0.046
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.954 0.046
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.954 0.046
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.954 0.046
G20 Parkinson's disease
0.000 0.956 0.044
G25.8 Other specified extrapyramidal and movement disorders
0.000 0.958 0.042
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.959 0.041
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.040 0.960 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.960 0.040
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.960 0.040
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.960 0.040
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.960 0.040
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.960 0.040
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.961 0.039
I68.0 Cerebral amyloid angiopathy
0.000 0.961 0.039
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.961 0.039
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.961 0.039
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.961 0.039
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.962 0.038
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.962 0.037
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.963 0.037
R22.9 Localised swelling, mass and lump, unspecified
0.037 0.963 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.963 0.037
T85 Complications of other internal prosthetic devices, implants and grafts
0.036 0.964 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.964 0.036
G30.8 Other Alzheimer's disease
0.001 0.964 0.035
I69.3 Sequelae of cerebral infarction
0.000 0.965 0.035
G30.1 Alzheimer's disease with late onset
0.001 0.965 0.034
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.034 0.966 0.000
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.966 0.034
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.966 0.034
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.966 0.034
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.966 0.033
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.966 0.034
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.966 0.034
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.967 0.033
I67 Other cerebrovascular diseases
0.000 0.967 0.033
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.968 0.032
I62.1 Nontraumatic extradural haemorrhage
0.000 0.968 0.032
T85.4 Mechanical complication of breast prosthesis and implant
0.032 0.968 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.968 0.031
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.969 0.031
I67.2 Cerebral atherosclerosis
0.000 0.970 0.030
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.030 0.970 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.029 0.971 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.029 0.971 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.971 0.029
G30.0 Alzheimer's disease with early onset
0.001 0.972 0.027
T85.2 Mechanical complication of intraocular lens
0.027 0.973 0.000
I61.8 Other intracerebral haemorrhage
0.000 0.973 0.027
G50-G59 Nerve, nerve root and plexus disorders
0.000 0.973 0.027
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.974 0.026
I65.2 Occlusion and stenosis of carotid artery
0.000 0.975 0.025
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.975 0.025
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.975 0.025
R26.8 Other and unspecified abnormalities of gait and mobility
0.000 0.976 0.024
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.976 0.024
I67.5 Moyamoya disease
0.000 0.976 0.024
I67.4 Hypertensive encephalopathy
0.000 0.976 0.024
I67.3 Progressive vascular leukoencephalopathy
0.000 0.976 0.024
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.024 0.976 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.024 0.976 0.000
G57 Mononeuropathies of lower limb
0.000 0.977 0.023
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.977 0.023
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.977 0.023
G57.1 Meralgia paraesthetica
0.000 0.978 0.022
G57.6 Lesion of plantar nerve
0.000 0.978 0.022
G53 Cranial nerve disorders in diseases classified elsewhere
0.000 0.979 0.021
G31.0 Circumscribed brain atrophy
0.000 0.979 0.021
G31.2 Degeneration of nervous system due to alcohol
0.000 0.980 0.020
G52 Disorders of other cranial nerves
0.000 0.980 0.020
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.020 0.980 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.019 0.981 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.981 0.019
R26 Abnormalities of gait and mobility
0.000 0.982 0.018
G57.5 Tarsal tunnel syndrome
0.000 0.982 0.018
R22.4 Localised swelling, mass and lump, lower limb
0.018 0.982 0.000
R22.1 Localised swelling, mass and lump, neck
0.018 0.982 0.000
G53.0 Postzoster neuralgia
0.000 0.983 0.017
G57.4 Lesion of medial popliteal nerve
0.000 0.983 0.017
G57.2 Lesion of femoral nerve
0.000 0.983 0.017
I67.8 Other specified cerebrovascular diseases
0.000 0.983 0.017
G52.9 Cranial nerve disorder, unspecified
0.000 0.983 0.016
R26.2 Difficulty in walking, not elsewhere classified
0.000 0.984 0.016
G52.3 Disorders of hypoglossal nerve
0.000 0.984 0.015
G53.8 Other cranial nerve disorders in other diseases classified elsewhere
0.000 0.984 0.015
G53.3 Multiple cranial nerve palsies in neoplastic disease
0.000 0.984 0.015
G53.2 Multiple cranial nerve palsies in sarcoidosis
0.000 0.984 0.015
G53.1 Multiple cranial nerve palsies in infectious and parasitic diseases classified elsewhere
0.000 0.984 0.015
G31.8 Other specified degenerative diseases of nervous system
0.000 0.984 0.015
R22.3 Localised swelling, mass and lump, upper limb
0.015 0.985 0.000
R26.3 Immobility
0.000 0.985 0.015
G50 Disorders of trigeminal nerve
0.000 0.985 0.015
G57.8 Other mononeuropathies of lower limb
0.000 0.985 0.015
G54 Nerve root and plexus disorders
0.000 0.985 0.015
G57.9 Mononeuropathy of lower limb, unspecified
0.000 0.985 0.014
G52.7 Disorders of multiple cranial nerves
0.000 0.985 0.014
G52.1 Disorders of glossopharyngeal nerve
0.000 0.985 0.014
G52.0 Disorders of olfactory nerve
0.000 0.985 0.014
G52.2 Disorders of vagus nerve
0.000 0.985 0.014
G57.3 Lesion of lateral popliteal nerve
0.000 0.986 0.014
G54.0 Brachial plexus disorders
0.000 0.986 0.014
G99.2 Myelopathy in diseases classified elsewhere
0.000 0.986 0.014
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.000 0.986 0.014
G59 Mononeuropathy in diseases classified elsewhere
0.000 0.986 0.014
R22.7 Localised swelling, mass and lump, multiple sites
0.013 0.986 0.000
R26.1 Paralytic gait
0.000 0.986 0.013
O03.4 Incomplete, without complication
0.000 0.987 0.013
G50.1 Atypical facial pain
0.000 0.987 0.013
G51 Facial nerve disorders
0.000 0.987 0.013
N60.3 Fibrosclerosis of breast
0.013 0.987 0.000
R26.0 Ataxic gait
0.000 0.987 0.012
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.988 0.012
I67.9 Cerebrovascular disease, unspecified
0.000 0.988 0.012
R22.2 Localised swelling, mass and lump, trunk
0.012 0.988 0.000
G57.0 Lesion of sciatic nerve
0.000 0.988 0.012
G54.5 Neuralgic amyotrophy
0.000 0.988 0.011
G54.2 Cervical root disorders, not elsewhere classified
0.000 0.988 0.011
R87.6 Abnormal cytological findings
0.000 0.989 0.011
G52.8 Disorders of other specified cranial nerves
0.000 0.989 0.011
G55.2 Nerve root and plexus compressions in spondylosis
0.000 0.989 0.011
G51.9 Disorder of facial nerve, unspecified
0.000 0.989 0.011
G50.8 Other disorders of trigeminal nerve
0.000 0.989 0.011
C44.5 Skin of trunk
0.011 0.989 0.000
G54.7 Phantom limb syndrome without pain
0.000 0.989 0.011
G54.3 Thoracic root disorders, not elsewhere classified
0.000 0.989 0.011
G54.1 Lumbosacral plexus disorders
0.000 0.990 0.010
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.000 0.990 0.010
G59.8 Other mononeuropathies in diseases classified elsewhere
0.000 0.990 0.010
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.000 0.990 0.010
G51.4 Facial myokymia
0.000 0.991 0.009
G51.2 Melkersson's syndrome
0.000 0.991 0.009
G51.1 Geniculate ganglionitis
0.000 0.991 0.009
M19.93 Arthrosis, unspecified (Forearm)
0.009 0.991 0.000
G54.6 Phantom limb syndrome with pain
0.000 0.991 0.009
G50.9 Disorder of trigeminal nerve, unspecified
0.000 0.991 0.009
G51.3 Clonic hemifacial spasm
0.000 0.991 0.009
G58 Other mononeuropathies
0.000 0.992 0.008
G54.8 Other nerve root and plexus disorders
0.001 0.992 0.008
G55.0 Nerve root and plexus compressions in neoplastic disease
0.000 0.992 0.008
T91.1 Sequelae of fracture of spine
0.000 0.992 0.008
G50.0 Trigeminal neuralgia
0.000 0.993 0.007
G54.4 Lumbosacral root disorders, not elsewhere classified
0.001 0.993 0.007
R29.6 Tendency to fall, not elsewhere classified
0.000 0.993 0.007
T91.3 Sequelae of injury of spinal cord
0.000 0.993 0.007
T91 Sequelae of injuries of neck and trunk
0.000 0.993 0.007
G55.3 Nerve root and plexus compressions in other dorsopathies
0.000 0.993 0.007
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.000 0.993 0.007
G51.8 Other disorders of facial nerve
0.000 0.994 0.006
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.000 0.994 0.006
T91.8 Sequelae of other specified injuries of neck and trunk
0.000 0.994 0.006
G58.0 Intercostal neuropathy
0.000 0.994 0.006
G30.9 Alzheimer's disease, unspecified
0.001 0.994 0.005
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.994 0.005
I67.1 Cerebral aneurysm, nonruptured
0.000 0.994 0.005
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.005 0.995 0.000
G58.9 Mononeuropathy, unspecified
0.000 0.995 0.005
R22.0 Localised swelling, mass and lump, head
0.005 0.995 0.000
R29.2 Abnormal reflex
0.000 0.995 0.005
T91.2 Sequelae of other fracture of thorax and pelvis
0.000 0.995 0.005
J32.8 Other chronic sinusitis
0.005 0.995 0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs
0.000 0.995 0.005
T91.4 Sequelae of injury of intrathoracic organs
0.000 0.995 0.005
T91.0 Sequelae of superficial injury and open wound of neck and trunk
0.000 0.995 0.005
J38.0 Paralysis of vocal cords and larynx
0.005 0.995 0.000
G58.7 Mononeuritis multiplex
0.001 0.995 0.004
G54.9 Nerve root and plexus disorder, unspecified
0.001 0.995 0.004
R29.4 Clicking hip
0.000 0.995 0.005
R29.3 Abnormal posture
0.000 0.995 0.005
J01.9 Acute sinusitis, unspecified
0.000 0.995 0.005
T91.9 Sequelae of unspecified injury of neck and trunk
0.000 0.995 0.005
R29.0 Tetany
0.000 0.995 0.004
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.000 0.995 0.005
G59.0 Diabetic mononeuropathy
0.000 0.995 0.004
R29.1 Meningismus
0.000 0.996 0.004
R87 Abnormal findings in specimens from female genital organs
0.000 0.996 0.004
O03 Spontaneous abortion
0.000 0.996 0.004
Z51.3 Blood transfusion without reported diagnosis
0.000 0.996 0.004
H92.1 Otorrhoea
0.004 0.996 0.000
F41.2 Mixed anxiety and depressive disorder
0.000 0.996 0.004
I72.4 Aneurysm of artery of lower extremity
0.000 0.996 0.004
R27 Other lack of coordination
0.000 0.996 0.003
M79.54 Residual foreign body in soft tissue (Hand)
0.000 0.997 0.003
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.000 0.997 0.003
G51.0 Bell's palsy
0.000 0.997 0.003
J06.9 Acute upper respiratory infection, unspecified
0.000 0.997 0.003
R87.8 Other abnormal findings
0.000 0.997 0.003
R87.4 Abnormal immunological findings
0.000 0.997 0.003
R87.3 Abnormal level of substances chiefly nonmedicinal as to source
0.000 0.997 0.003
R87.2 Abnormal level of other drugs, medicaments and biological substances
0.000 0.997 0.003
R87.1 Abnormal level of hormones
0.000 0.997 0.003
R87.0 Abnormal level of enzymes
0.000 0.997 0.003
O03.3 Incomplete, with other and unspecified complications
0.000 0.997 0.003
Q38.7 Pharyngeal pouch
0.003 0.997 0.000
R87.5 Abnormal microbiological findings
0.000 0.997 0.003
G40-G47 Episodic and paroxysmal disorders
0.000 0.997 0.003
N95.3 States associated with artificial menopause
0.000 0.997 0.003
O03.7 Complete or unspecified, complicated by embolism
0.000 0.997 0.003
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.000 0.997 0.003
O03.2 Incomplete, complicated by embolism
0.000 0.997 0.003
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.000 0.997 0.003
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.000 0.997 0.003
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.000 0.997 0.003
I33.0 Acute and subacute infective endocarditis
0.003 0.997 0.000
O03.8 Complete or unspecified, with other and unspecified complications
0.000 0.997 0.003
J01 Acute sinusitis
0.000 0.997 0.003
H58.8 Visual disturbances in diseases classified elsewhere
0.000 0.997 0.003
R27.8 Other and unspecified lack of coordination
0.000 0.997 0.003
S06.80 Other intracranial injuries (without open intracranial wound)
0.000 0.997 0.003
R87.9 Unspecified abnormal finding
0.000 0.997 0.003
R87.7 Abnormal histological findings
0.000 0.997 0.003
M48.09 Spinal stenosis (Site unspecified)
0.000 0.997 0.003
G58.8 Other specified mononeuropathies
0.001 0.997 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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