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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs502771
log Bayes Factor = 134.013
Chromosome 6   position 32,578,970  (GRCh37) Explore rs502771 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
D86 Sarcoidosis
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
N18 Chronic renal failure
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
N00-N08 Glomerular diseases
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
D80-D89 Certain disorders involving the immune mechanism
1.000 0.000 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
E27.1 Primary adrenocortical insufficiency
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
D69 Purpura and other haemorrhagic conditions
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
E27 Other disorders of adrenal gland
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N04 Nephrotic syndrome
1.000 0.000 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
D64 Other anaemias
1.000 0.000 0.000
N05 Unspecified nephritic syndrome
1.000 0.000 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
D50-D53 Nutritional anaemias
0.999 0.001 0.000
M35 Other systemic involvement of connective tissue
0.999 0.001 0.000
H30-H36 Disorders of choroid and retina
0.999 0.001 0.000
M35.0 Sicca syndrome [Sjogren]
0.999 0.001 0.000
E16 Other disorders of pancreatic internal secretion
0.999 0.001 0.000
E83.1 Disorders of iron metabolism
0.000 0.001 0.999
N04.9 Unspecified
0.999 0.001 0.000
D86.9 Sarcoidosis, unspecified
0.999 0.001 0.000
E16.2 Hypoglycaemia, unspecified
0.999 0.001 0.000
D86.0 Sarcoidosis of lung
0.998 0.002 0.000
M05 Seropositive rheumatoid arthritis
0.002 0.002 0.996
M05-M14 Inflammatory polyarthropathies
0.004 0.002 0.994
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.998 0.002 0.000
E10.1 With ketoacidosis
0.997 0.003 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.997 0.003 0.000
D69.6 Thrombocytopenia, unspecified
0.997 0.003 0.000
H06.2 Dysthyroid exophthalmos
0.996 0.004 0.000
D50 Iron deficiency anaemia
0.996 0.004 0.000
H36 Retinal disorders in diseases classified elsewhere
0.995 0.005 0.000
H02 Other disorders of eyelid
0.993 0.007 0.000
H36.0 Diabetic retinopathy
0.993 0.007 0.000
D50.9 Iron deficiency anaemia, unspecified
0.993 0.007 0.000
M15-M19 Arthrosis
0.992 0.008 0.000
N18.9 Chronic renal failure, unspecified
0.992 0.008 0.000
M06.3 Rheumatoid nodule
0.000 0.008 0.992
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.008 0.992
N05.2 Diffuse membranous glomerulonephritis
0.990 0.010 0.000
E14 Unspecified diabetes mellitus
0.989 0.011 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.988 0.012 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.986 0.014 0.000
Q60-Q64 Congenital malformations of the urinary system
0.986 0.014 0.000
M18 Arthrosis of first carpometacarpal joint
0.985 0.015 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.016 0.984
N18.4 Chronic kidney disease, stage 4
0.984 0.016 0.000
H34 Retinal vascular occlusions
0.982 0.018 0.000
N05.9 Unspecified
0.981 0.019 0.000
M24 Other specific joint derangements
0.981 0.019 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.978 0.022 0.000
H02.0 Entropion and trichiasis of eyelid
0.978 0.022 0.000
Q61 Cystic kidney disease
0.976 0.024 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.976 0.024 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.026 0.974
H34.8 Other retinal vascular occlusions
0.971 0.029 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.030 0.970
G56.0 Carpal tunnel syndrome
0.969 0.031 0.000
N18.5 Chronic kidney disease, stage 5
0.969 0.031 0.000
E10.2 With renal complications
0.968 0.032 0.000
G56 Mononeuropathies of upper limb
0.968 0.032 0.000
K50 Crohn's disease [regional enteritis]
0.000 0.032 0.968
M23 Internal derangement of knee
0.968 0.032 0.000
N18.0 End-stage renal disease
0.967 0.033 0.000
Chapter VI Diseases of the nervous system
0.966 0.034 0.000
E10.4 With neurological complications
0.963 0.037 0.000
M24.1 Other articular cartilage disorders
0.963 0.037 0.000
K50.9 Crohn's disease, unspecified
0.000 0.037 0.963
M86-M90 Other osteopathies
0.962 0.038 0.000
D68 Other coagulation defects
0.962 0.038 0.000
E70-E90 Metabolic disorders
0.959 0.041 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.957 0.043 0.000
H02.5 Other disorders affecting eyelid function
0.956 0.044 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.955 0.045 0.000
M17 Gonarthrosis [arthrosis of knee]
0.953 0.047 0.000
N17 Acute renal failure
0.953 0.047 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.050 0.950
E14.3 With ophthalmic complications
0.949 0.051 0.000
M21 Other acquired deformities of limbs
0.949 0.051 0.000
K50.8 Other Crohn's disease
0.000 0.052 0.948
M24.16 Other articular cartilage disorders (Lower leg)
0.946 0.054 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.945 0.055 0.000
E89.0 Postprocedural hypothyroidism
0.943 0.057 0.000
Q61.2 Polycystic kidney, adult type
0.941 0.059 0.000
K50.1 Crohn's disease of large intestine
0.000 0.060 0.940
G59.0 Diabetic mononeuropathy
0.940 0.060 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.939 0.061 0.000
D51 Vitamin B12 deficiency anaemia
0.937 0.063 0.000
Q61.3 Polycystic kidney, unspecified
0.935 0.065 0.000
N18.3 Chronic kidney disease, stage 3
0.934 0.066 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.933 0.067 0.000
M17.1 Other primary gonarthrosis
0.932 0.068 0.000
G51 Facial nerve disorders
0.931 0.069 0.000
E24 Cushing's syndrome
0.931 0.069 0.000
M21.0 Valgus deformity, not elsewhere classified
0.931 0.069 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.931 0.069 0.000
N17.9 Acute renal failure, unspecified
0.926 0.074 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.923 0.077 0.000
D68.8 Other specified coagulation defects
0.921 0.079 0.000
N04.2 Diffuse membranous glomerulonephritis
0.920 0.079 0.000
M23.3 Other meniscus derangements
0.918 0.082 0.000
D69.4 Other primary thrombocytopenia
0.918 0.082 0.000
G54 Nerve root and plexus disorders
0.918 0.082 0.000
K50-K52 Noninfective enteritis and colitis
0.009 0.085 0.906
M34 Systemic sclerosis
0.911 0.089 0.000
M17.0 Primary gonarthrosis, bilateral
0.907 0.093 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.094 0.906
M32 Systemic lupus erythematosus
0.906 0.094 0.000
M86 Osteomyelitis
0.904 0.096 0.000
K51 Ulcerative colitis
0.000 0.096 0.904
N04.1 Focal and segmental glomerular lesions
0.893 0.107 0.000
Chapter XX External causes of morbidity and mortality
0.892 0.108 0.000
E28 Ovarian dysfunction
0.891 0.109 0.000
D86.3 Sarcoidosis of skin
0.890 0.110 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.886 0.114 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.114 0.886
Q44.6 Cystic disease of liver
0.885 0.115 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.115 0.885
H02.4 Ptosis of eyelid
0.885 0.115 0.000
G51.0 Bell's palsy
0.882 0.118 0.000
M35.7 Hypermobility syndrome
0.882 0.118 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.878 0.122 0.000
E06 Thyroiditis
0.877 0.123 0.000
M60-M63 Disorders of muscles
0.876 0.124 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.875 0.125 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.127 0.873
G70-G73 Diseases of myoneural junction and muscle
0.872 0.128 0.000
Q43 Other congenital malformations of intestine
0.872 0.128 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.871 0.129 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.870 0.130 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.131 0.869
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.869 0.131 0.000
D61 Other aplastic anaemias
0.869 0.131 0.000
E10.0 With coma
0.867 0.133 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.866 0.134 0.000
E14.8 With unspecified complications
0.865 0.135 0.000
Chapter I Certain infectious and parasitic diseases
0.865 0.135 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.136 0.864
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.860 0.140 0.000
D68.5 Primary Thrombophilia
0.858 0.142 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.858 0.142 0.000
D52 Folate deficiency anaemia
0.856 0.144 0.000
N25-N29 Other disorders of kidney and ureter
0.855 0.145 0.000
M87 Osteonecrosis
0.855 0.145 0.000
N05.1 Focal and segmental glomerular lesions
0.852 0.148 0.000
M24.2 Disorder of ligament
0.852 0.148 0.000
E24.2 Drug-induced Cushing's syndrome
0.852 0.148 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.149 0.851
N40 Hyperplasia of prostate
0.000 0.150 0.850
A50-A64 Infections with a predominantly sexual mode of transmission
0.848 0.152 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.844 0.156 0.000
H02.6 Xanthelasma of eyelid
0.840 0.160 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.838 0.162 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.838 0.162 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.837 0.163 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.837 0.163 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.837 0.163 0.000
D86.1 Sarcoidosis of lymph nodes
0.835 0.165 0.000
N02 Recurrent and persistent haematuria
0.834 0.166 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.832 0.168 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.832 0.168 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.831 0.169 0.000
M20.1 Hallux valgus (acquired)
0.000 0.173 0.827
M15 Polyarthrosis
0.827 0.173 0.000
A63.0 Anogenital (venereal) warts
0.827 0.173 0.000
H10-H13 Disorders of conjunctiva
0.827 0.173 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.174 0.826
H35 Other retinal disorders
0.824 0.176 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.176 0.824
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.822 0.178 0.000
K50.0 Crohn's disease of small intestine
0.000 0.178 0.821
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.821 0.179 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.818 0.182 0.000
E14.1 With ketoacidosis
0.817 0.183 0.000
G58 Other mononeuropathies
0.816 0.184 0.000
G54.6 Phantom limb syndrome with pain
0.816 0.184 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.815 0.185 0.000
M86.9 Osteomyelitis, unspecified
0.814 0.186 0.000
W20-W49 Exposure to inanimate mechanical forces
0.812 0.188 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.809 0.191 0.000
Y52 Agents primarily affecting the cardiovascular system
0.808 0.192 0.000
D80 Immunodeficiency with predominantly antibody defects
0.806 0.194 0.000
G72 Other myopathies
0.806 0.194 0.000
B25-B34 Other viral diseases
0.803 0.197 0.000
H05 Disorders of orbit
0.801 0.199 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.799 0.200 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.799 0.201 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.797 0.203 0.000
E03.8 Other specified hypothyroidism
0.796 0.204 0.000
N02.2 Diffuse membranous glomerulonephritis
0.795 0.205 0.000
H43-H45 Disorders of vitreous body and globe
0.795 0.205 0.000
H50 Other strabismus
0.794 0.206 0.000
E10.7 With multiple complications
0.794 0.206 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.793 0.207 0.000
M60 Myositis
0.793 0.207 0.000
E14.2 Withrenal complications
0.790 0.210 0.000
E31 Polyglandular dysfunction
0.790 0.210 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.210 0.790
Q80-Q89 Other congenital malformations
0.789 0.211 0.000
N18.2 Chronic kidney disease, stage 2
0.788 0.212 0.000
M23.8 Other internal derangements of knee
0.786 0.214 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.786 0.214 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.785 0.215 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.785 0.215 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.785 0.215 0.000
D69.8 Other specified haemorrhagic conditions
0.784 0.216 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.217 0.783
D69.0 Allergic purpura
0.783 0.217 0.000
D86.8 Sarcoidosis of other and combined sites
0.783 0.217 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.781 0.219 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.219 0.781
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.220 0.780
K51.4 Pseudopolyposis of colon
0.000 0.220 0.780
E27.2 Addisonian crisis
0.778 0.222 0.000
E07 Other disorders of thyroid
0.777 0.223 0.000
Q00-Q07 Congenital malformations of the nervous system
0.777 0.223 0.000
M23.5 Chronic instability of knee
0.776 0.224 0.000
Q43.0 Meckel's diverticulum
0.776 0.224 0.000
M34.1 CR(E)ST syndrome
0.774 0.226 0.000
X20-X29 Contact with venomous animals and plants
0.772 0.228 0.000
N03 Chronic nephritic syndrome
0.772 0.228 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.231 0.769
D50.1 Sideropenic dysphagia
0.769 0.231 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.231 0.769
M24.27 Disorder of ligament (Ankle and foot)
0.768 0.232 0.000
V40-V49 Car occupant injured in transport accident
0.768 0.232 0.000
E24.0 Pituitary-dependent Cushing's disease
0.767 0.233 0.000
Y52.1 Calcium-channel blockers
0.767 0.233 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.766 0.234 0.000
E73 Lactose intolerance
0.764 0.235 0.000
E88 Other metabolic disorders
0.764 0.236 0.000
E10.5 With peripheral circulatory complications
0.764 0.236 0.000
E28.3 Primary ovarian failure
0.764 0.236 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.763 0.237 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.763 0.237 0.000
M90 Osteopathies in diseases classified elsewhere
0.762 0.238 0.000
E06.3 Autoimmune thyroiditis
0.762 0.238 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.762 0.238 0.000
M21.2 Flexion deformity
0.761 0.239 0.000
D69.2 Other nonthrombocytopenic purpura
0.761 0.239 0.000
E14.4 With neurological complications
0.761 0.239 0.000
M91-M94 Chondropathies
0.760 0.240 0.000
M87.9 Osteonecrosis, unspecified
0.760 0.240 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.760 0.240 0.000
D61.9 Aplastic anaemia, unspecified
0.759 0.241 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.242 0.758
D68.6 Other Thrombophilia
0.757 0.242 0.000
M22 Disorders of patella
0.757 0.243 0.000
M24.9 Joint derangement, unspecified
0.757 0.243 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.756 0.244 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.755 0.245 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.754 0.246 0.000
C81 Hodgkin's disease
0.753 0.247 0.000
D52.9 Folate deficiency anaemia, unspecified
0.753 0.247 0.000
E21.3 Hyperparathyroidism, unspecified
0.752 0.248 0.000
H35.8 Other specified retinal disorders
0.751 0.249 0.000
K51.8 Other ulcerative colitis
0.000 0.249 0.751
C83.3 Large cell (diffuse)
0.750 0.250 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.749 0.251 0.000
G51.9 Disorder of facial nerve, unspecified
0.748 0.252 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.748 0.252 0.000
M21.8 Other specified acquired deformities of limbs
0.747 0.253 0.000
D69.9 Haemorrhagic condition, unspecified
0.746 0.254 0.000
E70 Disorders of aromatic amino-acid metabolism
0.746 0.254 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.745 0.254 0.000
G51.3 Clonic hemifacial spasm
0.745 0.255 0.000
M35.2 Behcet's disease
0.745 0.255 0.000
M23.0 Cystic meniscus
0.744 0.256 0.000
D50.8 Other iron deficiency anaemias
0.744 0.256 0.000
Y57 Other and unspecified drugs and medicaments
0.743 0.257 0.000
M34.9 Systemic sclerosis, unspecified
0.743 0.257 0.000
H43 Disorders of vitreous body
0.743 0.257 0.000
M86.8 Other osteomyelitis
0.742 0.258 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.742 0.258 0.000
E16.1 Other hypoglycaemia
0.741 0.259 0.000
E78.1 Pure hyperglyceridaemia
0.737 0.263 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.737 0.263 0.000
E28.2 Polycystic ovarian syndrome
0.736 0.264 0.000
D83 Common variable immunodeficiency
0.736 0.264 0.000
Q44.5 Other congenital malformations of bile ducts
0.735 0.265 0.000
H02.1 Ectropion of eyelid
0.735 0.265 0.000
H05.2 Exophthalmic conditions
0.734 0.266 0.000
D68.0 Von Willebrand's disease
0.734 0.266 0.000
M34.0 Progressive systemic sclerosis
0.733 0.267 0.000
H34.9 Retinal vascular occlusion, unspecified
0.732 0.267 0.000
E14.5 With peripheral circulatory complications
0.732 0.268 0.000
M60.9 Myositis, unspecified
0.730 0.270 0.000
H50.2 Vertical strabismus
0.729 0.271 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.729 0.271 0.000
G52 Disorders of other cranial nerves
0.727 0.273 0.000
H43.8 Other disorders of vitreous body
0.725 0.275 0.000
V10-V19 Pedal cyclist injured in transport accident
0.725 0.275 0.000
E89.4 Postprocedural ovarian failure
0.724 0.276 0.000
H34.2 Other retinal artery occlusions
0.723 0.277 0.000
H30 Chorioretinal inflammation
0.723 0.277 0.000
Q61.9 Cystic kidney disease, unspecified
0.723 0.277 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.723 0.277 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.722 0.278 0.000
E14.9 Without complications
0.722 0.278 0.000
N18.8 Other chronic renal failure
0.721 0.279 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.717 0.283 0.000
N06 Isolated proteinuria with specified morphological lesion
0.717 0.283 0.000
N01 Rapidly progressive nephritic syndrome
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
D67 Hereditary factor IX deficiency
0.717 0.283 0.000
D81 Combined immunodeficiencies
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
E25 Adrenogenital disorders
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
D69.1 Qualitative platelet defects
0.717 0.283 0.000
E27.5 Adrenomedullary hyperfunction
0.717 0.283 0.000
E27.0 Other adrenocortical overactivity
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
N04.8 Other
0.717 0.283 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.717 0.283 0.000
N04.6 Dense deposit disease
0.717 0.283 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.717 0.283 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.717 0.283 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
N05.6 Dense deposit disease
0.717 0.283 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.717 0.283 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.717 0.283 0.000
N05.0 Minor glomerular abnormality
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.8 Other specified systemic involvement of connective tissue
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.716 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.716 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.716 0.283 0.000
E16.3 Increased secretion of glucagon
0.716 0.283 0.000
D82 Immunodeficiency associated with other major defects
0.716 0.283 0.000
C81.1 Nodular sclerosis
0.716 0.284 0.000
M23.4 Loose body in knee
0.716 0.284 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.715 0.284 0.000
M05.8 Other seropositive rheumatoid arthritis
0.001 0.284 0.714
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.001 0.284 0.714
M05.1 Rheumatoid lung disease
0.001 0.284 0.714
M05.0 Felty's syndrome
0.001 0.284 0.714
M09 Juvenile arthritis in diseases classified elsewhere
0.003 0.285 0.713
M08 Juvenile arthritis
0.003 0.285 0.713
H06.3 Other disorders of orbit in diseases classified elsewhere
0.715 0.285 0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.715 0.285 0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.715 0.285 0.000
Q50-Q56 Congenital malformations of genital organs
0.715 0.285 0.000
C81.9 Hodgkin's disease, unspecified
0.715 0.285 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.715 0.285 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.714 0.286 0.000
Q43.3 Congenital malformations of intestinal fixation
0.714 0.286 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.714 0.286 0.000
Q35-Q37 Cleft lip and cleft palate
0.713 0.287 0.000
H11 Other disorders of conjunctiva
0.713 0.287 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.713 0.287 0.000
M07 Psoriatic and enteropathic arthropathies
0.002 0.288 0.710
H02.7 Other degenerative disorders of eyelid and periocular area
0.712 0.288 0.000
Q60.0 Renal agenesis, unilateral
0.711 0.288 0.000
D53 Other nutritional anaemias
0.711 0.289 0.000
N00 Acute nephritic syndrome
0.711 0.289 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.289 0.711
M06.38 Rheumatoid nodule (Other)
0.000 0.289 0.711
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.289 0.711
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.289 0.711
M06.33 Rheumatoid nodule (Forearm)
0.000 0.289 0.711
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.289 0.711
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.289 0.711
G72.4 Inflammatory myopathy, not elsewhere classified
0.711 0.289 0.000
G58.9 Mononeuropathy, unspecified
0.710 0.290 0.000
E14.7 With multiple complications
0.709 0.291 0.000
E14.0 With coma
0.709 0.291 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.709 0.291 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.709 0.291 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.709 0.291 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.709 0.291 0.000
M14 Arthropathies in other diseases classified elsewhere
0.002 0.291 0.706
H35.2 Other proliferative retinopathy
0.708 0.292 0.000
E20 Hypoparathyroidism
0.707 0.292 0.000
E05.8 Other thyrotoxicosis
0.707 0.293 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.706 0.294 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.706 0.294 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.706 0.294 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.706 0.294 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.706 0.294 0.000
E10.8 With unspecified complications
0.705 0.295 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.705 0.295 0.000
Q85 Phakomatoses, not elsewhere classified
0.705 0.295 0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere
0.704 0.296 0.000
H34.0 Transient retinal artery occlusion
0.704 0.296 0.000
D63.0 Anaemia in neoplastic disease
0.704 0.296 0.000
Q39 Congenital malformations of oesophagus
0.703 0.297 0.000
G54.0 Brachial plexus disorders
0.703 0.297 0.000
G54.5 Neuralgic amyotrophy
0.702 0.298 0.000
Q45 Other congenital malformations of digestive system
0.701 0.298 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.701 0.298 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.701 0.298 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.701 0.299 0.000
W75-W84 Other accidental threats to breathing
0.700 0.300 0.000
D64.8 Other specified anaemias
0.700 0.300 0.000
Q61.8 Other cystic kidney diseases
0.700 0.300 0.000
Q61.4 Renal dysplasia
0.700 0.300 0.000
Q61.1 Polycystic kidney, infantile type
0.700 0.300 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.700 0.300 0.000
Y42.7 Androgens and anabolic congeners
0.700 0.300 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.699 0.301 0.000
H35.4 Peripheral retinal degeneration
0.699 0.301 0.000
E74 Other disorders of carbohydrate metabolism
0.699 0.301 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.697 0.302 0.000
E22 Hyperfunction of pituitary gland
0.697 0.303 0.000
N18.1 Chronic kidney disease, stage 1
0.697 0.303 0.000
D89.1 Cryoglobulinaemia
0.697 0.303 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.696 0.304 0.000
Q61.5 Medullary cystic kidney
0.695 0.305 0.000
N04.0 Minor glomerular abnormality
0.695 0.305 0.000
E06.5 Other chronic thyroiditis
0.694 0.306 0.000
M24.28 Disorder of ligament (Other)
0.694 0.306 0.000
M00-M03 Infectious arthropathies
0.693 0.307 0.000
M86.1 Other acute osteomyelitis
0.693 0.307 0.000
Y59 Other and unspecified vaccines and biological substances
0.692 0.308 0.000
Q63 Other congenital malformations of kidney
0.692 0.308 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.692 0.308 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.690 0.309 0.000
M24.18 Other articular cartilage disorders (Other)
0.690 0.309 0.000
M24.14 Other articular cartilage disorders (Hand)
0.690 0.309 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.690 0.309 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.690 0.309 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.690 0.310 0.000
M21.9 Acquired deformity of limb, unspecified
0.689 0.311 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.689 0.311 0.000
E84 Cystic fibrosis
0.688 0.312 0.000
E77 Disorders of glycoprotein metabolism
0.688 0.312 0.000
E76 Disorders of glycosaminoglycan metabolism
0.688 0.312 0.000
E72 Other disorders of amino-acid metabolism
0.688 0.312 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.688 0.312 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.688 0.312 0.000
G54.8 Other nerve root and plexus disorders
0.687 0.313 0.000
Q40 Other congenital malformations of upper alimentary tract
0.687 0.313 0.000
X23 Contact with hornets, wasps and bees
0.687 0.313 0.000
G71 Primary disorders of muscles
0.686 0.314 0.000
M60.99 Myositis, unspecified (Site unspecified)
0.686 0.314 0.000
A80-A89 Viral infections of the central nervous system
0.685 0.315 0.000
V80-V89 Other land transport accidents
0.685 0.315 0.000
M33 Dermatopolymyositis
0.685 0.315 0.000
G59.8 Other mononeuropathies in diseases classified elsewhere
0.684 0.315 0.000
B25 Cytomegaloviral disease
0.684 0.316 0.000
N17.2 Acute renal failure with medullary necrosis
0.683 0.317 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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