TreeWAS – Variant ID: rs519595

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.900	0.100
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.907	0.093
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.910	0.090
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.911	0.089
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.911	0.089
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.912	0.088
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.913	0.087
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.913	0.087
T36 Poisoning by systemic antibiotics	0.000	0.914	0.086
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.915	0.085
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.918	0.082
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.918	0.082
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.919	0.081
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.920	0.080
T39.0 Salicylates	0.000	0.923	0.077
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.924	0.076
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.925	0.075
T43.2 Other and unspecified antidepressants	0.000	0.925	0.075
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.926	0.074
T43.6 Psychostimulants with abuse potential	0.000	0.927	0.073
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.927	0.073
T45.0 Antiallergic and antiemetic drugs	0.000	0.927	0.072
T36.0 Penicillins	0.000	0.928	0.072
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.928	0.072
T45.2 Vitamins, not elsewhere classified	0.000	0.929	0.071
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.929	0.071
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.929	0.070
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.930	0.070
T50.8 Diagnostic agents	0.000	0.930	0.069
T47.4 Other laxatives	0.000	0.930	0.069
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.930	0.069
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.931	0.069
T36.3 Macrolides	0.000	0.931	0.069
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.931	0.069
T47.0 Histamine H(2)-receptor antagonists	0.000	0.931	0.069
T47.6 Antidiarrhoeal drugs	0.000	0.931	0.068
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.932	0.068
T38.5 Other oestrogens and progestogens	0.000	0.932	0.068
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.932	0.067
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.933	0.067
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.933	0.067
T46.1 Calcium-channel blockers	0.000	0.933	0.067
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.934	0.066
T43.9 Psychotropic drug, unspecified	0.000	0.934	0.066
T36.4 Tetracyclines	0.000	0.935	0.065
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.935	0.065
T47.2 Stimulant laxatives	0.000	0.935	0.064
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.936	0.064
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.936	0.064
T47.7 Emetics	0.000	0.936	0.064
T47.5 Digestants	0.000	0.936	0.064
T47.3 Saline and osmotic laxatives	0.000	0.936	0.064
T39.4 Antirheumatics, not elsewhere classified	0.000	0.936	0.064
T39.2 Pyrazolone derivatives	0.000	0.936	0.064
T50.7 Analeptics and opioid receptor antagonists	0.000	0.936	0.064
T50.5 Appetite depressants	0.000	0.936	0.064
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.936	0.064
T50.0 Mineralocorticoids and their antagonists	0.000	0.936	0.064
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.936	0.063
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.937	0.063
T45.8 Other primarily systemic and haematological agents	0.000	0.937	0.063
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.937	0.063
T45.6 Fibrinolysis-affecting drugs	0.000	0.937	0.063
T45.3 Enzymes, not elsewhere classified	0.000	0.937	0.063
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.937	0.062
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.937	0.062
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.937	0.062
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.937	0.062
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.937	0.062
T44.0 Anticholinesterase agents	0.000	0.937	0.062
T38.9 Other and unspecified hormone antagonists	0.000	0.937	0.062
T38.7 Androgens and anabolic congeners	0.000	0.937	0.062
T38.4 Oral contraceptives	0.000	0.937	0.062
T38.2 Antithyroid drugs	0.000	0.937	0.062
T36.9 Systemic antibiotic, unspecified	0.000	0.938	0.062
T36.7 Antifungal antibiotics, systemically used	0.000	0.938	0.062
T36.6 Rifamycins	0.000	0.938	0.062
T36.5 Aminoglycosides	0.000	0.938	0.062
T36.2 Chloramphenicol group	0.000	0.938	0.062
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.938	0.062
T45.5 Anticoagulants	0.000	0.939	0.061
F10 Mental and behavioural disorders due to use of alcohol	0.000	0.939	0.061
T45.4 Iron and its compounds	0.000	0.939	0.061
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.939	0.061
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.940	0.060
T38.0 Glucocorticoids and synthetic analogues	0.000	0.940	0.060
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.940	0.060
T50.4 Drugs affecting uric acid metabolism	0.000	0.941	0.059
T36.8 Other systemic antibiotics	0.000	0.941	0.059
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.941	0.059
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.941	0.059
T46.7 Peripheral vasodilators	0.000	0.941	0.059
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.941	0.059
T38.1 Thyroid hormones and substitutes	0.000	0.941	0.058
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.941	0.058
F10.2 Dependence syndrome	0.000	0.941	0.059
T50.1 Loop [high-ceiling] diuretics	0.000	0.941	0.058
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.942	0.058
F10.4 Withdrawal state with delirium	0.000	0.944	0.056
T41.2 Other and unspecified general anaesthetics	0.000	0.944	0.056
F10.0 Acute intoxication	0.000	0.944	0.056
M20.2 Hallux rigidus	0.056	0.944	0.000
T41.5 Therapeutic gases	0.000	0.946	0.053
T41.4 Anaesthetic, unspecified	0.000	0.946	0.053
T41.3 Local anaesthetics	0.000	0.946	0.053
T41.1 Intravenous anaesthetics	0.000	0.946	0.053
T41.0 Inhaled anaesthetics	0.000	0.946	0.053
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.946	0.053
F10.3 Withdrawal state	0.000	0.947	0.053
T48.5 Anti-common-cold drugs	0.000	0.947	0.053
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.947	0.053
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.947	0.053
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.947	0.053
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.947	0.053
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.947	0.052
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.947	0.052
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.947	0.052
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.948	0.052
T48.4 Expectorants	0.000	0.948	0.052
T48.3 Antitussives	0.000	0.948	0.052
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.948	0.052
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.948	0.052
T48.0 Oxytocic drugs	0.000	0.948	0.052
T39.1 4-Aminophenol derivatives	0.000	0.948	0.052
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.949	0.051
T37.5 Antiviral drugs	0.000	0.949	0.051
T37.4 Anthelminthics	0.000	0.949	0.051
T37.3 Other antiprotozoal drugs	0.000	0.949	0.051
T37.1 Antimycobacterial drugs	0.000	0.949	0.051
T37.0 Sulphonamides	0.000	0.949	0.051
T49.9 Topical agent, unspecified	0.000	0.950	0.050
T49.8 Other topical agents	0.000	0.950	0.050
T49.7 Dental drugs, topically applied	0.000	0.950	0.050
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.950	0.050
T49.5 Ophthalmological drugs and preparations	0.000	0.950	0.050
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.950	0.050
T49.3 Emollients, demulcents and protectants	0.000	0.950	0.050
T49.2 Local astringents and local detergents	0.000	0.950	0.050
T49.1 Antipruritics	0.000	0.950	0.050
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.951	0.049
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.952	0.048
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.952	0.048
T42.2 Succinimides and oxazolidinediones	0.000	0.952	0.048
T42.0 Hydantoin derivatives	0.000	0.952	0.048
F10.1 Harmful use	0.000	0.952	0.048
F10.6 Amnesic syndrome	0.000	0.953	0.047
T42.3 Barbiturates	0.000	0.953	0.047
F10.8 Other mental and behavioural disorders	0.000	0.954	0.046
F10.7 Residual and late-onset psychotic disorder	0.000	0.956	0.044
F10.9 Unspecified mental and behavioural disorder	0.000	0.956	0.044
F10.5 Psychotic disorder	0.000	0.956	0.043
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.000	0.960	0.040
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.961	0.039
T42.1 Iminostilbenes	0.000	0.961	0.039
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.963	0.037
F12 Mental and behavioural disorders due to use of cannabinoids	0.000	0.964	0.036
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.000	0.968	0.032
F12.1 Harmful use	0.000	0.968	0.032
T42.4 Benzodiazepines	0.000	0.968	0.032
F12.2 Dependence syndrome	0.000	0.969	0.031
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.000	0.970	0.030
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.000	0.971	0.029
F18 Mental and behavioural disorders due to use of volatile solvents	0.000	0.971	0.029
F16 Mental and behavioural disorders due to use of hallucinogens	0.000	0.971	0.029
T40.1 Heroin	0.000	0.972	0.028
F12.0 Acute intoxication	0.000	0.973	0.027
T40.5 Cocaine	0.000	0.973	0.027
F14 Mental and behavioural disorders due to use of cocaine	0.000	0.973	0.027
F13.3 Withdrawal state	0.000	0.973	0.027
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.973	0.026
T40.8 Lysergide [LSD]	0.000	0.973	0.026
T40.7 Cannabis (derivatives)	0.000	0.973	0.026
T40.0 Opium	0.000	0.973	0.026
T40.3 Methadone	0.000	0.973	0.026
F12.9 Unspecified mental and behavioural disorder	0.000	0.974	0.026
F12.8 Other mental and behavioural disorders	0.000	0.974	0.026
F12.7 Residual and late-onset psychotic disorder	0.000	0.974	0.026
F12.6 Amnesic syndrome	0.000	0.974	0.026
F12.4 Withdrawal state with delirium	0.000	0.974	0.026
F12.3 Withdrawal state	0.000	0.974	0.026
F11 Mental and behavioural disorders due to use of opioids	0.000	0.974	0.026
F12.5 Psychotic disorder	0.000	0.975	0.025
F17 Mental and behavioural disorders due to use of tobacco	0.000	0.976	0.024
F15.1 Harmful use	0.000	0.976	0.024
F13.2 Dependence syndrome	0.000	0.977	0.023
F13.9 Unspecified mental and behavioural disorder	0.000	0.977	0.023
F13.8 Other mental and behavioural disorders	0.000	0.977	0.023
F13.7 Residual and late-onset psychotic disorder	0.000	0.977	0.023
F13.6 Amnesic syndrome	0.000	0.977	0.023
F13.5 Psychotic disorder	0.000	0.977	0.023
F13.4 Withdrawal state with delirium	0.000	0.977	0.023
F13.0 Acute intoxication	0.000	0.977	0.023
F19.1 Harmful use	0.000	0.978	0.022
F15.9 Unspecified mental and behavioural disorder	0.000	0.978	0.022
F15.8 Other mental and behavioural disorders	0.000	0.978	0.022
F15.7 Residual and late-onset psychotic disorder	0.000	0.978	0.022
F15.6 Amnesic syndrome	0.000	0.978	0.022
F15.5 Psychotic disorder	0.000	0.978	0.022
F15.4 Withdrawal state with delirium	0.000	0.978	0.022
F15.3 Withdrawal state	0.000	0.978	0.022
F15.2 Dependence syndrome	0.000	0.978	0.022
F19.3 Withdrawal state	0.000	0.978	0.022
F13.1 Harmful use	0.000	0.979	0.021
F15.0 Acute intoxication	0.000	0.979	0.021
F19.5 Psychotic disorder	0.000	0.979	0.021
F19.9 Unspecified mental and behavioural disorder	0.000	0.979	0.021
F19.8 Other mental and behavioural disorders	0.000	0.979	0.021
F19.7 Residual and late-onset psychotic disorder	0.000	0.979	0.021
F19.6 Amnesic syndrome	0.000	0.979	0.021
F19.4 Withdrawal state with delirium	0.000	0.979	0.021
F19.0 Acute intoxication	0.000	0.979	0.021
F16.9 Unspecified mental and behavioural disorder	0.000	0.979	0.021
F16.8 Other mental and behavioural disorders	0.000	0.979	0.021
F16.7 Residual and late-onset psychotic disorder	0.000	0.979	0.021
F16.6 Amnesic syndrome	0.000	0.979	0.021
F16.5 Psychotic disorder	0.000	0.979	0.021
F16.4 Withdrawal state with delirium	0.000	0.979	0.021
F16.3 Withdrawal state	0.000	0.979	0.021
F16.2 Dependence syndrome	0.000	0.979	0.021
F16.1 Harmful use	0.000	0.979	0.021
F16.0 Acute intoxication	0.000	0.979	0.021
F18.9 Unspecified mental and behavioural disorder	0.000	0.979	0.021
F18.8 Other mental and behavioural disorders	0.000	0.979	0.021
F18.7 Residual and late-onset psychotic disorder	0.000	0.979	0.021
F18.6 Amnesic syndrome	0.000	0.979	0.021
F18.5 Psychotic disorder	0.000	0.979	0.021
F18.4 Withdrawal state with delirium	0.000	0.979	0.021
F18.3 Withdrawal state	0.000	0.979	0.021
F18.2 Dependence syndrome	0.000	0.979	0.021
F18.1 Harmful use	0.000	0.979	0.021
F18.0 Acute intoxication	0.000	0.979	0.021
T40.2 Other opioids	0.000	0.980	0.020
F17.1 Harmful use	0.000	0.980	0.020
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.000	0.980	0.020
F14.9 Unspecified mental and behavioural disorder	0.000	0.980	0.019
F14.8 Other mental and behavioural disorders	0.000	0.980	0.019
F14.7 Residual and late-onset psychotic disorder	0.000	0.980	0.019
F14.6 Amnesic syndrome	0.000	0.980	0.019
F14.5 Psychotic disorder	0.000	0.980	0.019
F14.4 Withdrawal state with delirium	0.000	0.980	0.019
F14.3 Withdrawal state	0.000	0.980	0.019
F14.0 Acute intoxication	0.000	0.980	0.019
F11.0 Acute intoxication	0.000	0.981	0.019
F19.2 Dependence syndrome	0.000	0.981	0.019
F11.9 Unspecified mental and behavioural disorder	0.000	0.981	0.019
F11.8 Other mental and behavioural disorders	0.000	0.981	0.019
F11.7 Residual and late-onset psychotic disorder	0.000	0.981	0.019
F11.6 Amnesic syndrome	0.000	0.981	0.019
F11.5 Psychotic disorder	0.000	0.981	0.019
F11.4 Withdrawal state with delirium	0.000	0.981	0.019
F14.1 Harmful use	0.000	0.981	0.019
T40.6 Other and unspecified narcotics	0.000	0.981	0.018
F14.2 Dependence syndrome	0.000	0.981	0.019
F11.1 Harmful use	0.000	0.981	0.018
F17.3 Withdrawal state	0.000	0.982	0.018
F11.3 Withdrawal state	0.000	0.982	0.018
T40.4 Other synthetic narcotics	0.000	0.982	0.018
F17.8 Other mental and behavioural disorders	0.000	0.982	0.017
F17.7 Residual and late-onset psychotic disorder	0.000	0.982	0.017
F17.6 Amnesic syndrome	0.000	0.982	0.017
F17.5 Psychotic disorder	0.000	0.982	0.017
F17.4 Withdrawal state with delirium	0.000	0.982	0.017
F11.2 Dependence syndrome	0.000	0.983	0.017
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.984	0.016
F17.0 Acute intoxication	0.000	0.984	0.016
F17.9 Unspecified mental and behavioural disorder	0.000	0.984	0.016
F17.2 Dependence syndrome	0.000	0.989	0.011
I22 Subsequent myocardial infarction	0.000	0.990	0.010
K25.7 Chronic without haemorrhage or perforation	0.000	0.991	0.009
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.991	0.009
I22.8 Subsequent myocardial infarction of other sites	0.000	0.992	0.008
E87.6 Hypokalaemia	0.000	0.992	0.008
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.993	0.007
Z63 Other problems related to primary support group, including family circumstances	0.000	0.993	0.007
Z63.0 Problems in relationship with spouse or partner	0.000	0.993	0.007
Z63.8 Other specified problems related to primary support group	0.000	0.993	0.007
K21 Gastro-oesophageal reflux disease	0.000	0.994	0.006
T51.9 Alcohol, unspecified	0.000	0.994	0.006
Z63.7 Other stressful life events affecting family and household	0.000	0.994	0.006
T51.0 Ethanol	0.000	0.994	0.006
Z63.5 Disruption of family by separation and divorce	0.000	0.994	0.006
T51 Toxic effect of alcohol	0.000	0.994	0.006
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.995	0.005
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.005	0.995	0.000
Z63.4 Disappearance and death of family member	0.000	0.995	0.005
K25.3 Acute without haemorrhage or perforation	0.000	0.995	0.005
Z63.9 Problem related to primary support group, unspecified	0.000	0.995	0.005
Z63.3 Absence of family member	0.000	0.995	0.005
Z63.2 Inadequate family support	0.000	0.995	0.005
Z63.1 Problems in relationship with parents and in-laws	0.000	0.995	0.005
T78.2 Anaphylactic shock, unspecified	0.000	0.995	0.005
K25 Gastric ulcer	0.000	0.995	0.005
K22.2 Oesophageal obstruction	0.000	0.995	0.005
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.000	0.995	0.005
J06.9 Acute upper respiratory infection, unspecified	0.000	0.995	0.005
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.005	0.995	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.005	0.995	0.000
Z63.6 Dependent relative needing care at home	0.000	0.995	0.005
Z96.1 Presence of intraocular lens	0.000	0.995	0.005
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.996	0.004
Z57.3 Occupational exposure to other air contaminants	0.000	0.996	0.004
Z57 Occupational exposure to risk-factors	0.000	0.996	0.004
Z56 Problems related to employment and unemployment	0.000	0.996	0.004
Z61 Problems related to negative life events in childhood	0.000	0.996	0.004
T51.8 Other alcohols	0.000	0.996	0.004
T51.3 Fusel oil	0.000	0.996	0.004
T51.2 2-Propanol	0.000	0.996	0.004
T51.1 Methanol	0.000	0.996	0.004
Z45.8 Adjustment and management of other implanted devices	0.000	0.996	0.004
Z58 Problems related to physical environment	0.000	0.996	0.004
Z58.1 Exposure to air pollution	0.000	0.996	0.004
M20.3 Other deformity of hallux (acquired)	0.004	0.996	0.000
M54.36 Sciatica (Lumbar region)	0.004	0.996	0.000
K22.8 Other specified diseases of oesophagus	0.000	0.996	0.004
K25.1 Acute with perforation	0.000	0.996	0.004
F79.9 Unspecified mental retardation (Without mention of impairment of behaviour)	0.000	0.996	0.004
Z59 Problems related to housing and economic circumstances	0.000	0.996	0.004
J15.2 Pneumonia due to staphylococcus	0.000	0.996	0.004
K25.2 Acute with both haemorrhage and perforation	0.000	0.996	0.004
Z56.0 Unemployment, unspecified	0.000	0.996	0.004
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.996	0.004
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.000	0.996	0.004
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.004	0.996	0.000
Z56.3 Stressful work schedule	0.000	0.996	0.004
T58 Toxic effect of carbon monoxide	0.000	0.996	0.004
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.000	0.996	0.004
S00.8 Superficial injury of other parts of head	0.000	0.996	0.004
Z59.1 Inadequate housing	0.000	0.996	0.004
F79 Unspecified mental retardation	0.000	0.996	0.004
Z62 Other problems related to upbringing	0.000	0.996	0.004
Z55 Problems related to education and literacy	0.000	0.996	0.004
K22.9 Disease of oesophagus, unspecified	0.000	0.996	0.004
M35.0 Sicca syndrome [Sjogren]	0.000	0.996	0.004
F70-F79 Mental retardation	0.000	0.996	0.004
Chapter V Mental and behavioural disorders	0.000	0.996	0.004
Z64 Problems related to certain psychosocial circumstances	0.000	0.996	0.004
F84 Pervasive developmental disorders	0.000	0.996	0.004
F80-F89 Disorders of psychological development	0.000	0.996	0.004
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.004	0.996	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.004	0.996	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.004	0.996	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.004	0.996	0.000
C83.0 Small cell (diffuse)	0.000	0.996	0.004
Z61.6 Problems related to alleged physical abuse of child	0.000	0.996	0.003
H71 Cholesteatoma of middle ear	0.000	0.996	0.004
Z58.5 Exposure to other pollution	0.000	0.996	0.003
F84.5 Asperger's syndrome	0.000	0.996	0.003
J15 Bacterial pneumonia, not elsewhere classified	0.000	0.996	0.004
H74.0 Tympanosclerosis	0.000	0.996	0.004
F60-F69 Disorders of adult personality and behaviour	0.000	0.996	0.004
H02.6 Xanthelasma of eyelid	0.000	0.996	0.004
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.003	0.996	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.996	0.003
K25.5 Chronic or unspecified with perforation	0.000	0.996	0.003
K25.0 Acute with haemorrhage	0.000	0.996	0.003
K27 Peptic ulcer, site unspecified	0.000	0.996	0.003
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.003	0.997	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.997	0.003
M54.3 Sciatica	0.003	0.997	0.000
Z56.7 Other and unspecified problems related to employment	0.000	0.997	0.003
Z57.8 Occupational exposure to other risk-factors	0.000	0.997	0.003
K22 Other diseases of oesophagus	0.000	0.997	0.003
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.003	0.997	0.000
Z56.5 Uncongenial work	0.000	0.997	0.003
Z56.2 Threat of job loss	0.000	0.997	0.003
Z56.1 Change of job	0.000	0.997	0.003
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.997	0.003
Z57.7 Occupational exposure to vibration	0.000	0.997	0.003
Z57.6 Occupational exposure to extreme temperature	0.000	0.997	0.003
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.997	0.003
Z57.1 Occupational exposure to radiation	0.000	0.997	0.003
Z57.0 Occupational exposure to noise	0.000	0.997	0.003
Z61.8 Other negative life events in childhood	0.000	0.997	0.003
Z61.9 Negative life events in childhood, unspecified	0.000	0.997	0.003
Z61.7 Personal frightening experience in childhood	0.000	0.997	0.003
Z61.3 Events resulting in loss of self-esteem in childhood	0.000	0.997	0.003
Z61.2 Altered pattern of family relationships in childhood	0.000	0.997	0.003
Z61.1 Removal from home in childhood	0.000	0.997	0.003
Z61.0 Loss of love relationship in childhood	0.000	0.997	0.003
H74 Other disorders of middle ear and mastoid	0.000	0.997	0.003
M54.39 Sciatica (Site unspecified)	0.003	0.997	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.000	0.997	0.003
Z58.9 Problem related to physical environment, unspecified	0.000	0.997	0.003
Z58.6 Inadequate drinking-water supply	0.000	0.997	0.003
Z58.4 Exposure to radiation	0.000	0.997	0.003
Z58.3 Exposure to soil pollution	0.000	0.997	0.003
Z58.2 Exposure to water pollution	0.000	0.997	0.003
Z58.0 Exposure to noise	0.000	0.997	0.003
T78 Adverse effects, not elsewhere classified	0.000	0.997	0.003
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.997	0.003
Z56.4 Discord with boss and workmates	0.000	0.997	0.003
Z57.2 Occupational exposure to dust	0.000	0.997	0.003
Z65 Problems related to other psychosocial circumstances	0.000	0.997	0.003
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.000	0.997	0.003
T54 Toxic effect of corrosive substances	0.000	0.997	0.003
T52 Toxic effect of organic solvents	0.000	0.997	0.003
K27.7 Chronic without haemorrhage or perforation	0.000	0.997	0.003
F69 Unspecified disorder of adult personality and behaviour	0.000	0.997	0.003
F84.0 Childhood autism	0.000	0.997	0.003
K20-K31 Diseases of oesophagus, stomach and duodenum	0.000	0.997	0.003
H66.3 Other chronic suppurative otitis media	0.000	0.997	0.003
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.000	0.997	0.003
Z59.7 Insufficient social insurance and welfare support	0.000	0.997	0.003
Z59.6 Low income	0.000	0.997	0.003
Z59.5 Extreme poverty	0.000	0.997	0.003
Z59.3 Problems related to living in residential institution	0.000	0.997	0.003
T63 Toxic effect of contact with venomous animals	0.000	0.997	0.003
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.997	0.003
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.997	0.003
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.000	0.997	0.003
T65 Toxic effect of other and unspecified substances	0.000	0.997	0.003
Z58.7 Exposure to tobacco smoke	0.000	0.997	0.003
Z59.2 Discord with neighbours, lodgers and landlord	0.000	0.997	0.003
F60 Specific personality disorders	0.000	0.997	0.003
F80 Specific developmental disorders of speech and language	0.000	0.997	0.003
J15.0 Pneumonia due to Klebsiella pneumoniae	0.000	0.997	0.003
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.997	0.003
J15.1 Pneumonia due to Pseudomonas	0.000	0.997	0.003
F70 Mild mental retardation	0.000	0.997	0.003
T60 Toxic effect of pesticides	0.000	0.997	0.003
T57 Toxic effect of other inorganic substances	0.000	0.997	0.003
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.000	0.997	0.003
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.000	0.997	0.003
T55 Toxic effect of soaps and detergents	0.000	0.997	0.003
J15.5 Pneumonia due to Escherichia coli	0.000	0.997	0.003
T78.4 Allergy, unspecified	0.000	0.997	0.003
Z59.4 Lack of adequate food	0.000	0.997	0.003
M20 Acquired deformities of fingers and toes	0.003	0.997	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.003	0.997	0.000
F60.3 Emotionally unstable personality disorder	0.000	0.997	0.003
F79.8 Unspecified mental retardation (Other impairments of behaviour)	0.000	0.997	0.003
F79.1 Unspecified mental retardation (Significant impairment of behaviour requiring attention or treatment)	0.000	0.997	0.003
F79.0 Unspecified mental retardation (With the statement of no, or minimal, impairment of behaviour)	0.000	0.997	0.003
K25.4 Chronic or unspecified with haemorrhage	0.000	0.997	0.003
J15.4 Pneumonia due to other streptococci	0.000	0.997	0.003
M46 Other inflammatory spondylopathies	0.003	0.997	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.000	0.997	0.003
C83.7 Burkitt's tumour	0.000	0.997	0.003
Z55.9 Problems relating to education and literacy, unspecified	0.000	0.997	0.003
Z55.8 Other problems relating to education and literacy	0.000	0.997	0.003
Z55.4 Educational maladjustment and discord with teachers and classmates	0.000	0.997	0.003
Z55.3 Underachievement in school	0.000	0.997	0.003
Z55.2 Failed examinations	0.000	0.997	0.003
Z55.1 Schooling unavailable and unattainable	0.000	0.997	0.003
Z55.0 Illiteracy and low-level literacy	0.000	0.997	0.003
Z62.9 Problem related to upbringing, unspecified	0.000	0.997	0.003
Z62.8 Other specified problems related to upbringing	0.000	0.997	0.003
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.000	0.997	0.003
Z62.5 Other problems related to neglect in upbringing	0.000	0.997	0.003
Z62.4 Emotional neglect of child	0.000	0.997	0.003
Z62.3 Hostility towards and scapegoating of child	0.000	0.997	0.003
Z62.2 Institutional upbringing	0.000	0.997	0.003
Z62.1 Parental overprotection	0.000	0.997	0.003
Z62.0 Inadequate parental supervision and control	0.000	0.997	0.003
T59 Toxic effect of other gases, fumes and vapours	0.000	0.997	0.003
H74.1 Adhesive middle ear disease	0.000	0.997	0.003
F78 Other mental retardation	0.000	0.997	0.003
F73 Profound mental retardation	0.000	0.997	0.003
F72 Severe mental retardation	0.000	0.997	0.003
F71 Moderate mental retardation	0.000	0.997	0.003
C83.3 Large cell (diffuse)	0.000	0.997	0.003
T62 Toxic effect of other noxious substances eaten as food	0.000	0.997	0.003
Z59.0 Homelessness	0.000	0.997	0.003
Z64.4 Discord with counsellors	0.000	0.997	0.003
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.000	0.997	0.003
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.000	0.997	0.003
Z64.1 Problems related to multiparity	0.000	0.997	0.003
M25.54 Pain in joint (Hand)	0.000	0.997	0.003
M54.30 Sciatica (Multiple sites in spine)	0.003	0.997	0.000
H74.4 Polyp of middle ear	0.000	0.997	0.003
Z56.6 Other physical and mental strain related to work	0.000	0.997	0.003
F84.9 Pervasive developmental disorder, unspecified	0.000	0.997	0.003
F84.8 Other pervasive developmental disorders	0.000	0.997	0.003
F84.4 Overactive disorder associated with mental retardation and stereotyped movements	0.000	0.997	0.003
F84.3 Other childhood disintegrative disorder	0.000	0.997	0.003
F84.2 Rett's syndrome	0.000	0.997	0.003
F84.1 Atypical autism	0.000	0.997	0.003
Z59.8 Other problems relating to housing and economic circumstances	0.000	0.997	0.003
F89 Unspecified disorder of psychological development	0.000	0.997	0.003
F88 Other disorders of psychological development	0.000	0.997	0.003
F83 Mixed specific developmental disorders	0.000	0.997	0.003
F82 Specific developmental disorder of motor function	0.000	0.997	0.003
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.000	0.997	0.003
C83.1 Small cleaved cell (diffuse)	0.000	0.997	0.003
F61 Mixed and other personality disorders	0.000	0.997	0.003
Z60 Problems related to social environment	0.000	0.997	0.003
V23.4 Driver injured in traffic accident	0.003	0.997	0.000
Z64.0 Problems related to unwanted pregnancy	0.000	0.997	0.003
K28 Gastrojejunal ulcer	0.000	0.997	0.003
T56 Toxic effect of metals	0.000	0.997	0.003
K27.3 Acute without haemorrhage or perforation	0.000	0.997	0.003
M46.2 Osteomyelitis of vertebra	0.003	0.997	0.000
H72 Perforation of tympanic membrane	0.000	0.997	0.003
J15.3 Pneumonia due to streptococcus, group B	0.000	0.997	0.003
T52.8 Other organic solvents	0.000	0.997	0.003
T54.9 Corrosive substance, unspecified	0.000	0.997	0.003
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.997	0.003
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.997	0.003
Z58.8 Other problems related to physical environment	0.000	0.997	0.003
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations