TreeWAS – Variant ID: rs525119

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.054	0.946
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.061	0.939
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.063	0.937
T50.9 Other and unspecified drugs, medicaments and biological substances	0.071	0.929
T43.2 Other and unspecified antidepressants	0.090	0.910
T46 Poisoning by agents primarily affecting the cardiovascular system	0.113	0.887
T46.4 Angiotensin-converting-enzyme inhibitors	0.160	0.840
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.162	0.838
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.180	0.820
T43.0 Tricyclic and tetracyclic antidepressants	0.184	0.816
T43.5 Other and unspecified antipsychotics and neuroleptics	0.188	0.812
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.221	0.779
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.232	0.768
T47.1 Other antacids and anti-gastric-secretion drugs	0.244	0.756
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.255	0.745
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.256	0.744
T50.6 Antidotes and chelating agents, not elsewhere classified	0.263	0.737
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.272	0.728
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.277	0.722
T43.4 Butyrophenone and thioxanthene neuroleptics	0.279	0.721
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.290	0.710
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.296	0.703
T50.1 Loop [high-ceiling] diuretics	0.298	0.702
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.299	0.701
T50.4 Drugs affecting uric acid metabolism	0.309	0.691
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.311	0.689
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.316	0.684
T43.6 Psychostimulants with abuse potential	0.319	0.681
T42.3 Barbiturates	0.319	0.681
T43.8 Other psychotropic drugs, not elsewhere classified	0.327	0.673
T50.7 Analeptics and opioid receptor antagonists	0.328	0.672
T50.5 Appetite depressants	0.328	0.672
T50.3 Electrolytic, caloric and water-balance agents	0.328	0.672
T50.0 Mineralocorticoids and their antagonists	0.328	0.672
T46.3 Coronary vasodilators, not elsewhere classified	0.328	0.672
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.345	0.655
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.349	0.650
T41 Poisoning by anaesthetics and therapeutic gases	0.352	0.648
T43.3 Phenothiazine antipsychotics and neuroleptics	0.355	0.645
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.356	0.644
T46.8 Antivaricose drugs, including sclerosing agents	0.364	0.636
T46.7 Peripheral vasodilators	0.364	0.636
T50.8 Diagnostic agents	0.365	0.635
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.375	0.625
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.379	0.621
T36 Poisoning by systemic antibiotics	0.379	0.620
T42.0 Hydantoin derivatives	0.382	0.618
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.386	0.614
T46.5 Other antihypertensive drugs, not elsewhere classified	0.387	0.612
T43.9 Psychotropic drug, unspecified	0.388	0.611
T46.1 Calcium-channel blockers	0.393	0.607
T40.2 Other opioids	0.394	0.606
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.394	0.606
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.394	0.606
T42.5 Mixed antiepileptics, not elsewhere classified	0.399	0.601
T42.2 Succinimides and oxazolidinediones	0.399	0.601
T40.5 Cocaine	0.403	0.597
T45.2 Vitamins, not elsewhere classified	0.404	0.596
T47.4 Other laxatives	0.405	0.595
T42.4 Benzodiazepines	0.410	0.590
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.410	0.589
T47.0 Histamine H(2)-receptor antagonists	0.411	0.589
T45.1 Antineoplastic and immunosuppressive drugs	0.412	0.588
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.412	0.588
T47.8 Other agents primarily affecting the gastro-intestinal system	0.412	0.588
T47.7 Emetics	0.412	0.588
T47.5 Digestants	0.412	0.588
T47.3 Saline and osmotic laxatives	0.412	0.588
T45.0 Antiallergic and antiemetic drugs	0.419	0.581
T38.0 Glucocorticoids and synthetic analogues	0.423	0.577
T40.1 Heroin	0.425	0.575
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.429	0.571
T47.6 Antidiarrhoeal drugs	0.440	0.560
T39.4 Antirheumatics, not elsewhere classified	0.441	0.558
T39.2 Pyrazolone derivatives	0.441	0.558
T45.9 Primarily systemic and haematological agent, unspecified	0.449	0.550
T45.8 Other primarily systemic and haematological agents	0.449	0.550
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.449	0.550
T45.6 Fibrinolysis-affecting drugs	0.449	0.550
T45.4 Iron and its compounds	0.449	0.550
T45.3 Enzymes, not elsewhere classified	0.449	0.550
T38.5 Other oestrogens and progestogens	0.457	0.543
T45.5 Anticoagulants	0.459	0.541
T38.8 Other and unspecified hormones and their synthetic substitutes	0.460	0.540
T38.1 Thyroid hormones and substitutes	0.466	0.534
T38.9 Other and unspecified hormone antagonists	0.466	0.534
T38.7 Androgens and anabolic congeners	0.466	0.534
T38.4 Oral contraceptives	0.466	0.534
T38.2 Antithyroid drugs	0.466	0.534
T48.5 Anti-common-cold drugs	0.466	0.533
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.470	0.530
T39.0 Salicylates	0.475	0.525
T42.1 Iminostilbenes	0.475	0.525
T47.2 Stimulant laxatives	0.477	0.523
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.478	0.522
T40.8 Lysergide [LSD]	0.478	0.522
T40.7 Cannabis (derivatives)	0.478	0.522
T40.0 Opium	0.478	0.522
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.484	0.516
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.488	0.512
T49.9 Topical agent, unspecified	0.495	0.504
T49.8 Other topical agents	0.495	0.504
T49.7 Dental drugs, topically applied	0.495	0.504
T49.6 Otorhinolaryngological drugs and preparations	0.495	0.504
T49.5 Ophthalmological drugs and preparations	0.495	0.504
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.495	0.504
T49.3 Emollients, demulcents and protectants	0.495	0.504
T49.2 Local astringents and local detergents	0.495	0.504
T49.1 Antipruritics	0.495	0.504
T40.3 Methadone	0.497	0.503
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.497	0.502
T48.4 Expectorants	0.497	0.502
T48.3 Antitussives	0.497	0.502
T48.2 Other and unspecified agents primarily acting on muscles	0.497	0.502
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.497	0.502
T48.0 Oxytocic drugs	0.497	0.502
T48.6 Antiasthmatics, not elsewhere classified	0.507	0.493
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.510	0.490
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.510	0.490
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.510	0.490
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.510	0.490
T44.1 Other parasympathomimetics [cholinergics]	0.510	0.490
T44.0 Anticholinesterase agents	0.510	0.490
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.514	0.486
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.521	0.479
T41.5 Therapeutic gases	0.535	0.464
T41.4 Anaesthetic, unspecified	0.535	0.464
T41.3 Local anaesthetics	0.535	0.464
T41.1 Intravenous anaesthetics	0.535	0.464
T41.0 Inhaled anaesthetics	0.535	0.464
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.538	0.462
T37.5 Antiviral drugs	0.538	0.462
T37.4 Anthelminthics	0.538	0.462
T37.3 Other antiprotozoal drugs	0.538	0.462
T37.1 Antimycobacterial drugs	0.538	0.462
T37.0 Sulphonamides	0.538	0.462
T36.4 Tetracyclines	0.544	0.456
T36.3 Macrolides	0.550	0.450
T37.2 Antimalarials and drugs acting on other blood protozoa	0.554	0.445
T37.8 Other specified systemic anti-infectives and antiparasitics	0.554	0.445
T36.9 Systemic antibiotic, unspecified	0.555	0.445
T36.7 Antifungal antibiotics, systemically used	0.555	0.445
T36.6 Rifamycins	0.555	0.445
T36.5 Aminoglycosides	0.555	0.445
T36.2 Chloramphenicol group	0.555	0.445
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.556	0.444
T41.2 Other and unspecified general anaesthetics	0.565	0.434
T39.1 4-Aminophenol derivatives	0.566	0.434
T36.8 Other systemic antibiotics	0.571	0.429
T40.6 Other and unspecified narcotics	0.575	0.424
T36.0 Penicillins	0.580	0.420
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.585	0.415
T40.4 Other synthetic narcotics	0.614	0.385
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.725	0.275
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.725	0.275
T18 Foreign body in alimentary tract	0.726	0.274
T15-T19 Effects of foreign body entering through natural orifice	0.727	0.273
T18.1 Foreign body in oesophagus	0.727	0.273
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.727	0.273
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.734	0.266
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.745	0.255
S60-S69 Injuries to the wrist and hand	0.750	0.250
T00-T07 Injuries involving multiple body regions	0.751	0.249
S60 Superficial injury of wrist and hand	0.758	0.242
T80 Complications following infusion, transfusion and therapeutic injection	0.758	0.242
T86 Failure and rejection of transplanted organs and tissues	0.759	0.241
S90-S99 Injuries to the ankle and foot	0.761	0.239
T85 Complications of other internal prosthetic devices, implants and grafts	0.762	0.238
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.769	0.231
S60.9 Superficial injury of wrist and hand, unspecified	0.773	0.227
T87 Complications peculiar to reattachment and amputation	0.775	0.225
S64 Injury of nerves at wrist and hand level	0.777	0.223
T00 Superficial injuries involving multiple body regions	0.777	0.223
T18.0 Foreign body in mouth	0.780	0.220
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.780	0.220
T16 Foreign body in ear	0.783	0.217
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.784	0.216
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.791	0.209
S62 Fracture at wrist and hand level	0.794	0.206
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.794	0.206
S96 Injury of muscle and tendon at ankle and foot level	0.794	0.206
T86.8 Failure and rejection of other transplanted organs and tissues	0.796	0.204
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.796	0.204
T83.0 Mechanical complication of urinary (indwelling) catheter	0.797	0.203
T18.9 Foreign body in alimentary tract, part unspecified	0.797	0.203
T18.3 Foreign body in small intestine	0.797	0.203
T83.2 Mechanical complication of graft of urinary organ	0.797	0.202
T18.5 Foreign body in anus and rectum	0.801	0.199
T26-T28 Burns and corrosions confined to eye and internal organs	0.801	0.199
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.801	0.199
T33-T35 Frostbite	0.802	0.197
T19 Foreign body in genito-urinary tract	0.803	0.197
S60.2 Contusion of other parts of wrist and hand	0.803	0.197
T86.0 Bone-marrow transplant rejection	0.803	0.197
S64.1 Injury of median nerve at wrist and hand level	0.803	0.197
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.803	0.197
S66 Injury of muscle and tendon at wrist and hand level	0.803	0.196
T18.8 Foreign body in other and multiple parts of alimentary tract	0.804	0.196
T18.4 Foreign body in colon	0.804	0.196
S60.7 Multiple superficial injuries of wrist and hand	0.804	0.196
S92 Fracture of foot, except ankle	0.804	0.196
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.805	0.195
T01 Open wounds involving multiple body regions	0.807	0.193
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.807	0.193
T15 Foreign body on external eye	0.807	0.193
S91 Open wound of ankle and foot	0.808	0.192
T83.3 Mechanical complication of intra-uterine contraceptive device	0.808	0.192
S64.0 Injury of ulnar nerve at wrist and hand level	0.808	0.192
S60.0 Contusion of finger(s) without damage to nail	0.808	0.192
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.810	0.190
T02 Fractures involving multiple body regions	0.811	0.189
T00.9 Multiple superficial injuries, unspecified	0.811	0.189
S98 Traumatic amputation of ankle and foot	0.812	0.188
T18.2 Foreign body in stomach	0.814	0.186
T79-T79 Certain early complications of trauma	0.814	0.186
S64.3 Injury of digital nerve of thumb	0.814	0.186
T87.6 Other and unspecified complications of amputation stump	0.814	0.186
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.814	0.186
S62.3 Fracture of other metacarpal bone	0.816	0.184
T88 Other complications of surgical and medical care, not elsewhere classified	0.817	0.183
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.817	0.183
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.817	0.183
S69 Other and unspecified injuries of wrist and hand	0.819	0.181
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.821	0.179
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.821	0.179
T05 Traumatic amputations involving multiple body regions	0.821	0.179
T04 Crushing injuries involving multiple body regions	0.821	0.179
T03 Dislocations, sprains and strains involving multiple body regions	0.821	0.179
T07 Unspecified multiple injuries	0.821	0.179
S68 Traumatic amputation of wrist and hand	0.822	0.178
T87.4 Infection of amputation stump	0.822	0.178
T00.8 Superficial injuries involving other combinations of body regions	0.824	0.176
T06 Other injuries involving multiple body regions, not elsewhere classified	0.826	0.174
T86.4 Liver transplant failure and rejection	0.826	0.174
T80.6 Other serum reactions	0.826	0.173
T80.5 Anaphylactic shock due to serum	0.826	0.173
T80.4 Rh incompatibility reaction	0.826	0.173
T80.3 ABO incompatibility reaction	0.826	0.173
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.826	0.173
T86.3 Heart-lung transplant failure and rejection	0.827	0.173
T86.2 Heart transplant failure and rejection	0.827	0.173
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.827	0.173
S62.30 Fracture of other metacarpal bone (closed)	0.827	0.173
S20-S29 Injuries to the thorax	0.827	0.173
S95 Injury of blood vessels at ankle and foot level	0.828	0.172
S94 Injury of nerves at ankle and foot level	0.828	0.172
S92.3 Fracture of metatarsal bone	0.828	0.172
S60.8 Other superficial injuries of wrist and hand	0.828	0.171
S99 Other and unspecified injuries of ankle and foot	0.828	0.171
S64.7 Injury of multiple nerves at wrist and hand level	0.829	0.171
S62.6 Fracture of other finger	0.831	0.169
T17 Foreign body in respiratory tract	0.834	0.166
T00.2 Superficial injuries involving multiple regions of upper limb(s)	0.834	0.166
T66-T78 Other and unspecified effects of external causes	0.835	0.165
S96.8 Injury of other muscles and tendons at ankle and foot level	0.835	0.165
S91.2 Open wound of toe(s) with damage to nail	0.836	0.164
S65 Injury of blood vessels at wrist and hand level	0.836	0.164
S60.1 Contusion of finger(s) with damage to nail	0.838	0.161
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.838	0.161
T87.2 Complications of other reattached body part	0.838	0.161
T87.1 Complications of reattached (part of) lower extremity	0.838	0.161
T87.0 Complications of reattached (part of) upper extremity	0.838	0.161
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.838	0.161
S91.3 Open wound of other parts of foot	0.839	0.161
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.839	0.160
S64.9 Injury of unspecified nerve at wrist and hand level	0.840	0.160
S64.8 Injury of other nerves at wrist and hand level	0.840	0.160
T00.1 Superficial injuries involving thorax with abdomen, lower back and pelvis	0.840	0.160
T00.0 Superficial injuries involving head with neck	0.840	0.160
S62.2 Fracture of first metacarpal bone	0.840	0.160
S67 Crushing injury of wrist and hand	0.840	0.160
S62.8 Fracture of other and unspecified parts of wrist and hand	0.841	0.159
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.841	0.159
T86.1 Kidney transplant failure and rejection	0.842	0.158
S97 Crushing injury of ankle and foot	0.843	0.157
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.844	0.156
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.844	0.156
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.844	0.156
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.844	0.156
T87.3 Neuroma of amputation stump	0.844	0.156
S27 Injury of other and unspecified intrathoracic organs	0.845	0.155
S92.30 Fracture of metatarsal bone (closed)	0.846	0.154
T20-T25 Burns and corrosions of external body surface, specified by site	0.846	0.154
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.847	0.153
T87.5 Necrosis of amputation stump	0.847	0.153
T01.8 Open wounds involving other combinations of body regions	0.847	0.153
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.847	0.153
S98.1 Traumatic amputation of one toe	0.849	0.151
T00.6 Superficial injuries involving multiple regions of upper limb(s) with lower limb(s)	0.850	0.150
T29 Burns and corrosions of multiple body regions	0.852	0.148
T19.0 Foreign body in urethra	0.852	0.148
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.852	0.148
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.852	0.148
T02.8 Fractures involving other combinations of body regions	0.852	0.147
T15.0 Foreign body in cornea	0.853	0.147
S62.7 Multiple fractures of fingers	0.853	0.147
T88.9 Complication of surgical and medical care, unspecified	0.853	0.147
T19.2 Foreign body in vulva and vagina	0.853	0.146
S92.2 Fracture of other tarsal bone(s)	0.853	0.146
S68.0 Traumatic amputation of thumb (complete)(partial)	0.854	0.146
T59 Toxic effect of other gases, fumes and vapours	0.855	0.144
T26 Burn and corrosion confined to eye and adnexa	0.856	0.144
S92.9 Fracture of foot, unspecified	0.856	0.144
S92.5 Fracture of other toe	0.856	0.144
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.857	0.143
T28 Burn and corrosion of other internal organs	0.857	0.143
T27 Burn and corrosion of respiratory tract	0.857	0.143
T02.4 Fractures involving multiple regions of both upper limbs	0.857	0.143
T30 Burn and corrosion, body region unspecified	0.857	0.143
T85.2 Mechanical complication of intraocular lens	0.857	0.142
T35 Frostbite involving multiple body regions and unspecified frostbite	0.858	0.142
T34 Frostbite with tissue necrosis	0.858	0.142
T33 Superficial frostbite	0.858	0.142
T19.9 Foreign body in genito-urinary tract, part unspecified	0.858	0.141
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.858	0.141
T19.3 Foreign body in uterus [any part]	0.858	0.141
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.859	0.141
S90 Superficial injury of ankle and foot	0.859	0.141
T01.3 Open wounds involving multiple regions of lower limb(s)	0.859	0.141
S92.7 Multiple fractures of foot	0.859	0.141
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.860	0.140
T32 Corrosions classified according to extent of body surface involved	0.861	0.139
T01.9 Multiple open wounds, unspecified	0.861	0.139
T01.6 Open wounds involving multiple regions of upper limb(s) with lower limb(s)	0.861	0.139
T01.1 Open wounds involving thorax with abdomen, lower back and pelvis	0.861	0.139
T01.0 Open wounds involving head with neck	0.861	0.139
S62.1 Fracture of other carpal bone(s)	0.861	0.139
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.861	0.138
T15.8 Foreign body in other and multiple parts of external eye	0.862	0.138
S91.7 Multiple open wounds of ankle and foot	0.862	0.138
T01.2 Open wounds involving multiple regions of upper limb(s)	0.862	0.137
S69.7 Multiple injuries of wrist and hand	0.862	0.137
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.863	0.137
S92.4 Fracture of great toe	0.863	0.136
S10-S19 Injuries to the neck	0.864	0.136
T02.9 Multiple fractures, unspecified	0.864	0.136
T02.7 Fractures involving thorax with lower back and pelvis with limb(s)	0.864	0.136
T02.6 Fractures involving multiple regions of upper limb(s) with lower limb(s)	0.864	0.136
T02.3 Fractures involving multiple regions of one lower limb	0.864	0.136
T02.1 Fractures involving thorax with lower back and pelvis	0.864	0.136
T02.0 Fractures involving head with neck	0.864	0.136
T83.1 Mechanical complication of other urinary devices and implants	0.864	0.136
S92.1 Fracture of talus	0.865	0.135
T88.7 Unspecified adverse effect of drug or medicament	0.865	0.135
T63 Toxic effect of contact with venomous animals	0.865	0.135
S98.4 Traumatic amputation of foot, level unspecified	0.865	0.135
S98.3 Traumatic amputation of other parts of foot	0.865	0.135
S98.2 Traumatic amputation of two or more toes	0.865	0.135
S98.0 Traumatic amputation of foot at ankle level	0.865	0.135
S62.4 Multiple fractures of metacarpal bones	0.865	0.134
T15.1 Foreign body in conjunctival sac	0.866	0.134
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.866	0.134
T54 Toxic effect of corrosive substances	0.866	0.134
S62.0 Fracture of navicular [scaphoid] bone of hand	0.866	0.134
T88.3 Malignant hyperthermia due to anaesthesis	0.866	0.133
T02.5 Fractures involving multiple regions of both lower limbs	0.867	0.133
T25 Burn and corrosion of ankle and foot	0.867	0.133
S27.1 Traumatic haemothorax	0.867	0.133
T82.4 Mechanical complication of vascular dialysis catheter	0.867	0.133
S62.61 Fracture of other finger (open)	0.867	0.133
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.867	0.133
S62.60 Fracture of other finger (closed)	0.867	0.133
T70 Effects of air pressure and water pressure	0.868	0.132
T31 Burns classified according to extent of body surface involved	0.868	0.132
T51 Toxic effect of alcohol	0.868	0.132
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.868	0.132
T88.1 Other complications following immunisation, not elsewhere classified	0.868	0.131
T88.0 Infection following immunisation	0.868	0.131
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.869	0.131
T60 Toxic effect of pesticides	0.869	0.131
T57 Toxic effect of other inorganic substances	0.869	0.131
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.869	0.131
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.869	0.131
T68 Hypothermia	0.869	0.131
S27.2 Traumatic heamopneumothorax	0.869	0.131
T02.2 Fractures involving multiple regions of one upper limb	0.870	0.130
T19.1 Foreign body in bladder	0.870	0.129
T17.2 Foreign body in pharynx	0.871	0.129
T61 Toxic effect of noxious substances eaten as seafood	0.871	0.129
T52 Toxic effect of organic solvents	0.871	0.129
S50-S59 Injuries to the elbow and forearm	0.871	0.129
T15.9 Foreign body on external eye, unspecified	0.871	0.128
T03.9 Multiple dislocations, sprains and strains, unspecified	0.871	0.128
T03.8 Dislocations, sprains and strains involving other combinations of body regions	0.871	0.128
T03.4 Dislocations, sprains and strains involving multiple regions of upper limb(s) with lower limb(s)	0.871	0.128
T03.3 Dislocations, sprains and strains involving multiple regions of lower limb(s)	0.871	0.128
T03.2 Dislocations, sprains and strains involving multiple regions of upper limb(s)	0.871	0.128
T03.1 Dislocations, sprains and strains involving thorax with lower back and pelvis	0.871	0.128
T03.0 Dislocations, sprains and strains involving head with neck	0.871	0.128
T04.9 Multiple crushing injuries, unspecified	0.871	0.128
T04.8 Crushing injuries involving other combinations of body regions	0.871	0.128
T04.7 Crushing injuries of thorax with abdomen, lower back and pelvis with limb(s)	0.871	0.128
T04.4 Crushing injuries involving multiple regions of upper limb(s) with lower limb(s)	0.871	0.128
T04.3 Crushing injuries involving multiple regions of lower limb(s)	0.871	0.128
T04.2 Crushing injuries involving multiple regions of upper limb(s)	0.871	0.128
T04.1 Crushing injuries involving thorax with abdomen, lower back and pelvis	0.871	0.128
T04.0 Crushing injuries involving head with neck	0.871	0.128
T05.9 Multiple traumatic amputations, unspecified	0.871	0.128
T05.8 Traumatic amputations involving other combinations of body regions	0.871	0.128
T05.6 Traumatic amputation of upper and lower limbs, any combination [any level]	0.871	0.128
T05.5 Traumatic amputation of both legs [any level]	0.871	0.128
T05.4 Traumatic amputation of one foot and other leg [any level, except foot]	0.871	0.128
T05.3 Traumatic amputation of both feet	0.871	0.128
T05.2 Traumatic amputation of both arms [any level]	0.871	0.128
T05.1 Traumatic amputation of one hand and other arm [any level, except hand]	0.871	0.128
T05.0 Traumatic amputation of both hands	0.871	0.128
S69.8 Other specified injuries of wrist and hand	0.872	0.128
T56 Toxic effect of metals	0.872	0.128
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.872	0.128
S68.8 Traumatic amputation of other parts of wrist and hand	0.872	0.128
S68.4 Traumatic amputation of hand at wrist level	0.872	0.128
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.872	0.128
S91.1 Open wound of toe(s) without damage to nail	0.872	0.128
T55 Toxic effect of soaps and detergents	0.872	0.128
T66 Unspecified effects of radiation	0.872	0.128
T62 Toxic effect of other noxious substances eaten as food	0.872	0.127
S62.20 Fracture of first metacarpal bone (closed)	0.873	0.127
T88.5 Other complications of anaesthesia	0.874	0.126
T06.8 Other specified injuries involving multiple body regions	0.875	0.125
T06.5 Injuries of intrathoracic organs with intra-abdominal and pelvic organs	0.875	0.125
T06.3 Injuries of blood vessels involving multiple body regions	0.875	0.125
T06.2 Injuries of nerves involving multiple body regions	0.875	0.125
T06.1 Injuries of nerves and spinal cord involving other multiple body regions	0.875	0.125
T06.0 Injuries of brain and cranial nerves with injuries of nerves and spinal cord at neck level	0.875	0.125
S26 Injury of heart	0.875	0.125
T17.3 Foreign body in larynx	0.875	0.125
S69.9 Unspecified injury of wrist and hand	0.876	0.124
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.876	0.124
S25 Injury of blood vessels of thorax	0.876	0.124
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.876	0.124
S27.3 Other injuries of lung	0.876	0.124
S99.9 Unspecified injury of ankle and foot	0.876	0.124
S94.9 Injury of unspecified nerve at ankle and foot level	0.876	0.123
S94.8 Injury of other nerves at ankle and foot level	0.876	0.123
S94.7 Injury of multiple nerves at ankle and foot level	0.876	0.123
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.876	0.123
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.876	0.123
S94.1 Injury of medial plantar nerve	0.876	0.123
S94.0 Injury of lateral plantar nerve	0.876	0.123
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.876	0.123
S95.8 Injury of other blood vessels at ankle and foot level	0.876	0.123
S95.7 Injury of multiple blood vessels at ankle and foot level	0.876	0.123
S95.2 Injury of dorsal vein of foot	0.876	0.123
S95.1 Injury of plantar artery of foot	0.876	0.123
S95.0 Injury of dorsal artery of foot	0.876	0.123
S92.31 Fracture of metatarsal bone (open)	0.877	0.123
S99.7 Multiple injuries of ankle and foot	0.877	0.123
T58 Toxic effect of carbon monoxide	0.877	0.123
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.877	0.123
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.877	0.123
T79 Certain early complications of trauma, not elsewhere classified	0.878	0.122
T80.2 Infections following infusion, transfusion and therapeutic injection	0.878	0.122
S99.8 Other specified injuries of ankle and foot	0.878	0.122
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.879	0.121
T59.9 Gases, fumes and vapours, unspecified	0.879	0.121
S20 Superficial injury of thorax	0.879	0.121
S65.0 Injury of ulnar artery at wrist and hand level	0.879	0.121
T06.4 Injuries of muscles and tendons involving multiple body regions	0.879	0.121
S65.4 Injury of blood vessel(s) of thumb	0.879	0.120
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.880	0.120
S92.0 Fracture of calcaneus	0.880	0.119
T17.4 Foreign body in trachea	0.881	0.119
T17.1 Foreign body in nostril	0.881	0.119
T17.0 Foreign body in nasal sinus	0.881	0.119
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.881	0.119
T82.0 Mechanical complication of heart valve prosthesis	0.881	0.119
T74 Maltreatment syndromes	0.881	0.119
T73 Effects of other deprivation	0.881	0.119
T69 Other effects of reduced temperature	0.881	0.119
T67 Effects of heat and light	0.881	0.119
S93.0 Dislocation of ankle joint	0.881	0.118
S64.4 Injury of digital nerve of other finger	0.882	0.118
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.882	0.118
S65.8 Injury of other blood vessels at wrist and hand level	0.882	0.118
S65.7 Injury of multiple blood vessels at wrist and hand level	0.882	0.118
S65.3 Injury of deep palmar arch	0.882	0.118
S65.2 Injury of superficial palmar arch	0.882	0.118
T02.80 Fractures involving other combinations of body regions (closed)	0.882	0.117
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.883	0.117
S93.3 Dislocation of other and unspecified parts of foot	0.884	0.116
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.884	0.116
T65 Toxic effect of other and unspecified substances	0.884	0.116
S24 Injury of nerves and spinal cord at thorax level	0.884	0.115
S62.21 Fracture of first metacarpal bone (open)	0.885	0.115
T17.5 Foreign body in bronchus	0.885	0.114
S62.31 Fracture of other metacarpal bone (open)	0.886	0.114
S92.50 Fracture of other toe (closed)	0.886	0.114
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.887	0.113
S65.5 Injury of blood vessel(s) of other finger	0.887	0.113
S97.0 Crushing injury of ankle	0.887	0.113
T25.2 Burn of second degree of ankle and foot	0.887	0.113
S93.4 Sprain and strain of ankle	0.888	0.112
S93.5 Sprain and strain of toe(s)	0.888	0.112
S97.1 Crushing injury of toe(s)	0.888	0.112
S27.8 Injury of other specified intrathoracic organs	0.888	0.112
T17.8 Foreign body in other and multiple parts of respiratory tract	0.888	0.112
T29.3 Burns of multiple regions, at least one burn of third degree mentioned	0.888	0.112
S27.9 Injury of unspecified intrathoracic organ	0.888	0.111
S27.7 Multiple injuries of intrathoracic organs	0.888	0.111
S27.6 Injury of pleura	0.888	0.111

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations