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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs525592
log Bayes Factor = 2.20229
Chromosome 11   position 68,195,104  (GRCh37) Explore rs525592 on Ensembl!
Variant rs525592 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.011 0.989
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.014 0.986
T43.2 Other and unspecified antidepressants
0.000 0.019 0.981
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.046 0.954
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.051 0.949
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.058 0.942
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.065 0.935
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.068 0.932
T40.2 Other opioids
0.000 0.075 0.925
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.086 0.914
T39.0 Salicylates
0.000 0.093 0.907
T45.0 Antiallergic and antiemetic drugs
0.000 0.118 0.882
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.145 0.855
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.163 0.837
T46.1 Calcium-channel blockers
0.000 0.167 0.833
T39.1 4-Aminophenol derivatives
0.000 0.198 0.802
T40.6 Other and unspecified narcotics
0.000 0.209 0.791
T45.5 Anticoagulants
0.000 0.219 0.781
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.221 0.779
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.222 0.778
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.248 0.752
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.261 0.739
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.279 0.721
T43.6 Psychostimulants with abuse potential
0.000 0.288 0.712
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.291 0.709
T43.9 Psychotropic drug, unspecified
0.000 0.291 0.709
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.291 0.709
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.293 0.707
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.293 0.707
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.311 0.689
T39.4 Antirheumatics, not elsewhere classified
0.000 0.316 0.684
T39.2 Pyrazolone derivatives
0.000 0.316 0.684
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.319 0.681
T40.8 Lysergide [LSD]
0.000 0.319 0.681
T40.7 Cannabis (derivatives)
0.000 0.319 0.681
T40.5 Cocaine
0.000 0.319 0.681
T40.3 Methadone
0.000 0.319 0.681
T40.1 Heroin
0.000 0.319 0.681
T40.0 Opium
0.000 0.319 0.681
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.326 0.674
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.329 0.671
T45.8 Other primarily systemic and haematological agents
0.000 0.329 0.671
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.329 0.671
T45.6 Fibrinolysis-affecting drugs
0.000 0.329 0.671
T45.4 Iron and its compounds
0.000 0.329 0.671
T45.3 Enzymes, not elsewhere classified
0.000 0.329 0.671
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.340 0.660
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.342 0.658
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.342 0.658
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.344 0.656
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.344 0.656
T46.7 Peripheral vasodilators
0.000 0.344 0.656
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.344 0.656
T45.2 Vitamins, not elsewhere classified
0.000 0.363 0.637
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.366 0.634
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.383 0.617
T38.1 Thyroid hormones and substitutes
0.000 0.396 0.604
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.399 0.601
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.409 0.591
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.415 0.584
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.000 0.430 0.570
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.439 0.561
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.441 0.558
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.441 0.558
T47.7 Emetics
0.000 0.441 0.558
T47.6 Antidiarrhoeal drugs
0.000 0.441 0.558
T47.5 Digestants
0.000 0.441 0.558
T47.4 Other laxatives
0.000 0.441 0.558
T47.3 Saline and osmotic laxatives
0.000 0.441 0.558
T47.2 Stimulant laxatives
0.000 0.441 0.558
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.456 0.544
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.461 0.539
T37.5 Antiviral drugs
0.000 0.461 0.539
T37.4 Anthelminthics
0.000 0.461 0.539
T37.3 Other antiprotozoal drugs
0.000 0.461 0.539
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.461 0.539
T37.1 Antimycobacterial drugs
0.000 0.461 0.539
T37.0 Sulphonamides
0.000 0.461 0.539
T36 Poisoning by systemic antibiotics
0.000 0.465 0.534
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.467 0.533
T38.9 Other and unspecified hormone antagonists
0.000 0.470 0.530
T38.7 Androgens and anabolic congeners
0.000 0.470 0.530
T38.4 Oral contraceptives
0.000 0.470 0.530
T38.2 Antithyroid drugs
0.000 0.470 0.530
T38.0 Glucocorticoids and synthetic analogues
0.000 0.470 0.530
T50.4 Drugs affecting uric acid metabolism
0.000 0.475 0.525
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.489 0.510
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.491 0.508
T48.5 Anti-common-cold drugs
0.000 0.491 0.508
T48.4 Expectorants
0.000 0.491 0.508
T48.3 Antitussives
0.000 0.491 0.508
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.491 0.508
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.491 0.508
T48.0 Oxytocic drugs
0.000 0.491 0.508
T47.0 Histamine H(2)-receptor antagonists
0.000 0.491 0.508
T41.5 Therapeutic gases
0.000 0.493 0.507
T41.4 Anaesthetic, unspecified
0.000 0.493 0.507
T41.3 Local anaesthetics
0.000 0.493 0.507
T41.2 Other and unspecified general anaesthetics
0.000 0.493 0.507
T41.1 Intravenous anaesthetics
0.000 0.493 0.507
T41.0 Inhaled anaesthetics
0.000 0.493 0.507
T49.9 Topical agent, unspecified
0.000 0.493 0.507
T49.8 Other topical agents
0.000 0.493 0.507
T49.7 Dental drugs, topically applied
0.000 0.493 0.507
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.493 0.507
T49.5 Ophthalmological drugs and preparations
0.000 0.493 0.507
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.493 0.507
T49.3 Emollients, demulcents and protectants
0.000 0.493 0.507
T49.2 Local astringents and local detergents
0.000 0.493 0.507
T49.1 Antipruritics
0.000 0.493 0.507
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.493 0.507
M81.99 Osteoporosis, unspecified (Site unspecified)
0.473 0.527 0.000
T50.7 Analeptics and opioid receptor antagonists
0.000 0.528 0.472
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.528 0.472
T50.5 Appetite depressants
0.000 0.528 0.472
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.528 0.472
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.528 0.472
T50.1 Loop [high-ceiling] diuretics
0.000 0.528 0.472
T50.0 Mineralocorticoids and their antagonists
0.000 0.528 0.472
T40.4 Other synthetic narcotics
0.000 0.540 0.460
T38.5 Other oestrogens and progestogens
0.000 0.544 0.455
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.553 0.446
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.554 0.446
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.557 0.443
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.557 0.443
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.557 0.443
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.557 0.443
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.557 0.443
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.557 0.443
T44.0 Anticholinesterase agents
0.000 0.557 0.443
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.570 0.430
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.582 0.417
T50.8 Diagnostic agents
0.000 0.608 0.391
T36.9 Systemic antibiotic, unspecified
0.000 0.616 0.383
T36.8 Other systemic antibiotics
0.000 0.616 0.383
T36.7 Antifungal antibiotics, systemically used
0.000 0.616 0.383
T36.6 Rifamycins
0.000 0.616 0.383
T36.5 Aminoglycosides
0.000 0.616 0.383
T36.2 Chloramphenicol group
0.000 0.616 0.383
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.618 0.381
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.620 0.380
T36.4 Tetracyclines
0.000 0.624 0.376
T36.0 Penicillins
0.000 0.642 0.357
T36.3 Macrolides
0.000 0.661 0.339
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.001 0.669 0.330
M81.9 Osteoporosis, unspecified
0.296 0.704 0.000
T42.1 Iminostilbenes
0.000 0.716 0.284
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.717 0.283
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.727 0.273
T42.2 Succinimides and oxazolidinediones
0.000 0.727 0.273
T42.3 Barbiturates
0.000 0.744 0.256
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.745 0.255
M81.96 Osteoporosis, unspecified (Lower leg)
0.248 0.751 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.755 0.245
M81.98 Osteoporosis, unspecified (Other)
0.240 0.760 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.235 0.765 0.000
T42.0 Hydantoin derivatives
0.000 0.775 0.225
M81.94 Osteoporosis, unspecified (Hand)
0.223 0.777 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.220 0.780 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.212 0.787 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.212 0.787 0.000
M81 Osteoporosis without pathological fracture
0.170 0.830 0.000
T42.4 Benzodiazepines
0.000 0.840 0.160
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.151 0.849 0.000
M81.0 Postmenopausal osteoporosis
0.136 0.864 0.000
M81.8 Other osteoporosis
0.131 0.869 0.000
M81.1 Postoophorectomy osteoporosis
0.130 0.870 0.000
M81.6 Localised osteoporosis [Lequesne]
0.122 0.878 0.000
M81.5 Idiopathic osteoporosis
0.122 0.878 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.113 0.887 0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)
0.112 0.888 0.000
M81.2 Osteoporosis of disuse
0.111 0.889 0.000
M81.4 Drug-induced osteoporosis
0.108 0.892 0.000
M81.80 Other osteoporosis (Multiple sites)
0.103 0.897 0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)
0.101 0.899 0.000
M81.08 Postmenopausal osteoporosis (Other)
0.098 0.902 0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)
0.098 0.902 0.000
M81.06 Postmenopausal osteoporosis (Lower leg)
0.098 0.902 0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)
0.098 0.902 0.000
M81.04 Postmenopausal osteoporosis (Hand)
0.098 0.902 0.000
M81.03 Postmenopausal osteoporosis (Forearm)
0.098 0.902 0.000
M81.02 Postmenopausal osteoporosis (Upper arm)
0.098 0.902 0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)
0.098 0.902 0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)
0.098 0.902 0.000
M81.89 Other osteoporosis (Site unspecified)
0.094 0.906 0.000
M81.88 Other osteoporosis (Other)
0.094 0.906 0.000
M81.87 Other osteoporosis (Ankle and foot)
0.094 0.906 0.000
M81.86 Other osteoporosis (Lower leg)
0.094 0.906 0.000
M81.85 Other osteoporosis (Pelvic region and thigh)
0.094 0.906 0.000
M81.84 Other osteoporosis (Hand)
0.094 0.906 0.000
M81.83 Other osteoporosis (Forearm)
0.094 0.906 0.000
M81.82 Other osteoporosis (Upper arm)
0.094 0.906 0.000
M81.81 Other osteoporosis (Shoulder region)
0.094 0.906 0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)
0.093 0.907 0.000
M81.18 Postoophorectomy osteoporosis (Other)
0.093 0.907 0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)
0.093 0.907 0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)
0.093 0.907 0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)
0.093 0.907 0.000
M81.14 Postoophorectomy osteoporosis (Hand)
0.093 0.907 0.000
M81.13 Postoophorectomy osteoporosis (Forearm)
0.093 0.907 0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)
0.093 0.907 0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)
0.093 0.907 0.000
M81.59 Idiopathic osteoporosis (Site unspecified)
0.088 0.912 0.000
M81.58 Idiopathic osteoporosis (Other)
0.088 0.912 0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)
0.088 0.912 0.000
M81.56 Idiopathic osteoporosis (Lower leg)
0.088 0.912 0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)
0.088 0.912 0.000
M81.54 Idiopathic osteoporosis (Hand)
0.088 0.912 0.000
M81.53 Idiopathic osteoporosis (Forearm)
0.088 0.912 0.000
M81.52 Idiopathic osteoporosis (Upper arm)
0.088 0.912 0.000
M81.51 Idiopathic osteoporosis (Shoulder region)
0.088 0.912 0.000
M81.50 Idiopathic osteoporosis (Multiple sites)
0.088 0.912 0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)
0.088 0.912 0.000
M81.68 Localized osteoporosis [Lequesne] (Other)
0.088 0.912 0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)
0.088 0.912 0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)
0.088 0.912 0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)
0.088 0.912 0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)
0.088 0.912 0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)
0.088 0.912 0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)
0.088 0.912 0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)
0.088 0.912 0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)
0.088 0.912 0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)
0.081 0.919 0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)
0.081 0.919 0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)
0.081 0.919 0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)
0.081 0.919 0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)
0.081 0.919 0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)
0.081 0.919 0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)
0.081 0.919 0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)
0.081 0.919 0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)
0.081 0.919 0.000
M81.29 Osteoporosis of disuse (Site unspecified)
0.080 0.920 0.000
M81.28 Osteoporosis of disuse (Other)
0.080 0.920 0.000
M81.27 Osteoporosis of disuse (Ankle and foot)
0.080 0.920 0.000
M81.26 Osteoporosis of disuse (Lower leg)
0.080 0.920 0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)
0.080 0.920 0.000
M81.24 Osteoporosis of disuse (Hand)
0.080 0.920 0.000
M81.23 Osteoporosis of disuse (Forearm)
0.080 0.920 0.000
M81.22 Osteoporosis of disuse (Upper arm)
0.080 0.920 0.000
M81.21 Osteoporosis of disuse (Shoulder region)
0.080 0.920 0.000
M81.49 Drug-induced osteoporosis (Site unspecified)
0.079 0.921 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.079 0.921 0.000
M81.48 Drug-induced osteoporosis (Other)
0.078 0.922 0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)
0.078 0.922 0.000
M81.46 Drug-induced osteoporosis (Lower leg)
0.078 0.922 0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)
0.078 0.922 0.000
M81.44 Drug-induced osteoporosis (Hand)
0.078 0.922 0.000
M81.43 Drug-induced osteoporosis (Forearm)
0.078 0.922 0.000
M81.42 Drug-induced osteoporosis (Upper arm)
0.078 0.922 0.000
M81.41 Drug-induced osteoporosis (Shoulder region)
0.078 0.922 0.000
M80-M85 Disorders of bone density and structure
0.073 0.927 0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)
0.071 0.928 0.000
Z91.5 Personal history of self-harm
0.000 0.931 0.069
M81.20 Osteoporosis of disuse (Multiple sites)
0.069 0.931 0.000
M82 Osteoporosis in diseases classified elsewhere
0.064 0.936 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.061 0.939 0.000
M82.1 Osteoporosis in endocrine disorders
0.058 0.942 0.000
M83 Adult osteomalacia
0.054 0.945 0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)
0.051 0.949 0.000
M84 Disorders of continuity of bone
0.050 0.950 0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.047 0.952 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.046 0.954 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.046 0.954 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.046 0.954 0.000
M80 Osteoporosis with pathological fracture
0.044 0.956 0.000
M85 Other disorders of bone density and structure
0.042 0.958 0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)
0.042 0.958 0.000
M82.18 Osteoporosis in endocrine disorders (Other)
0.042 0.958 0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)
0.042 0.958 0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)
0.042 0.958 0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)
0.042 0.958 0.000
M82.14 Osteoporosis in endocrine disorders (Hand)
0.042 0.958 0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)
0.042 0.958 0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)
0.042 0.958 0.000
M83.1 Senile osteomalacia
0.042 0.958 0.000
M83.3 Adult osteomalacia due to malnutrition
0.041 0.959 0.000
M83.9 Adult osteomalacia, unspecified
0.039 0.961 0.000
M83.5 Other drug-induced osteomalacia in adults
0.039 0.961 0.000
M83.4 Aluminum bone disease
0.039 0.961 0.000
M83.2 Adult osteomalacia due to malabsorption
0.039 0.961 0.000
M83.0 Puerperal osteomalacia
0.039 0.961 0.000
M84.4 Pathological fracture, not elsewhere classified
0.039 0.961 0.000
M84.0 Malunion of fracture
0.038 0.962 0.000
M84.3 Stress fracture, not elsewhere classified
0.037 0.963 0.000
M83.8 Other adult osteomalacia
0.037 0.963 0.000
M84.8 Other disorders of continuity of bone
0.036 0.964 0.000
M84.9 Disorder of continuity of bone, unspecified
0.036 0.964 0.000
M85.8 Other specified disorders of bone density and structure
0.034 0.965 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.034 0.966 0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)
0.034 0.966 0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)
0.033 0.967 0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)
0.033 0.967 0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)
0.033 0.967 0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)
0.033 0.967 0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)
0.033 0.967 0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)
0.033 0.967 0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)
0.033 0.967 0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)
0.033 0.967 0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)
0.033 0.967 0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)
0.033 0.967 0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)
0.033 0.967 0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)
0.033 0.967 0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)
0.033 0.967 0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)
0.033 0.967 0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)
0.033 0.967 0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)
0.033 0.967 0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)
0.033 0.967 0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)
0.033 0.967 0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)
0.033 0.967 0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)
0.033 0.967 0.000
M83.12 Senile osteomalacia (Upper arm)
0.032 0.967 0.000
M84.2 Delayed union of fracture
0.032 0.968 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.032 0.968 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.032 0.968 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.032 0.968 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.031 0.969 0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)
0.031 0.969 0.000
M80.8 Other osteoporosis with pathological fracture
0.031 0.969 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.031 0.969 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.031 0.969 0.000
M85.9 Disorder of bone density and structure, unspecified
0.030 0.969 0.000
M85.5 Aneurysmal bone cyst
0.030 0.970 0.000
M85.4 Solitary bone cyst
0.030 0.970 0.000
M85.3 Osteitis condensans
0.030 0.970 0.000
M85.1 Skeletal fluorosis
0.030 0.970 0.000
M83.19 Senile osteomalacia (Site unspecified)
0.030 0.970 0.000
M83.18 Senile osteomalacia (Other)
0.030 0.970 0.000
M83.17 Senile osteomalacia (Ankle and foot)
0.030 0.970 0.000
M83.16 Senile osteomalacia (Lower leg)
0.030 0.970 0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)
0.030 0.970 0.000
M83.14 Senile osteomalacia (Hand)
0.030 0.970 0.000
M83.13 Senile osteomalacia (Forearm)
0.030 0.970 0.000
M83.11 Senile osteomalacia (Shoulder region)
0.030 0.970 0.000
M83.10 Senile osteomalacia (Multiple sites)
0.030 0.970 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.030 0.970 0.000
M84.01 Malunion of fracture (Shoulder region)
0.030 0.970 0.000
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)
0.029 0.970 0.000
M83.38 Adult osteomalacia due to malnutrition (Other)
0.029 0.970 0.000
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)
0.029 0.970 0.000
M83.36 Adult osteomalacia due to malnutrition (Lower leg)
0.029 0.970 0.000
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)
0.029 0.970 0.000
M83.34 Adult osteomalacia due to malnutrition (Hand)
0.029 0.970 0.000
M83.33 Adult osteomalacia due to malnutrition (Forearm)
0.029 0.970 0.000
M83.32 Adult osteomalacia due to malnutrition (Upper arm)
0.029 0.970 0.000
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)
0.029 0.970 0.000
M84.04 Malunion of fracture (Hand)
0.029 0.970 0.000
M85.2 Hyperostosis of skull
0.029 0.971 0.000
M84.02 Malunion of fracture (Upper arm)
0.029 0.971 0.000
M83.09 Puerperal osteomalacia (Site unspecified)
0.028 0.971 0.000
M83.08 Puerperal osteomalacia (Other)
0.028 0.971 0.000
M83.07 Puerperal osteomalacia (Ankle and foot)
0.028 0.971 0.000
M83.06 Puerperal osteomalacia (Lower leg)
0.028 0.971 0.000
M83.05 Puerperal osteomalacia (Pelvic region and thigh)
0.028 0.971 0.000
M83.04 Puerperal osteomalacia (Hand)
0.028 0.971 0.000
M83.03 Puerperal osteomalacia (Forearm)
0.028 0.971 0.000
M83.02 Puerperal osteomalacia (Upper arm)
0.028 0.971 0.000
M83.01 Puerperal osteomalacia (Shoulder region)
0.028 0.971 0.000
M83.00 Puerperal osteomalacia (Multiple sites)
0.028 0.971 0.000
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)
0.028 0.971 0.000
M83.28 Adult osteomalacia due to malabsorption (Other)
0.028 0.971 0.000
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)
0.028 0.971 0.000
M83.26 Adult osteomalacia due to malabsorption (Lower leg)
0.028 0.971 0.000
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)
0.028 0.971 0.000
M83.24 Adult osteomalacia due to malabsorption (Hand)
0.028 0.971 0.000
M83.23 Adult osteomalacia due to malabsorption (Forearm)
0.028 0.971 0.000
M83.22 Adult osteomalacia due to malabsorption (Upper arm)
0.028 0.971 0.000
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)
0.028 0.971 0.000
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)
0.028 0.971 0.000
M83.49 Aluminium bone disease (Site unspecified)
0.028 0.971 0.000
M83.48 Aluminium bone disease (Other)
0.028 0.971 0.000
M83.47 Aluminium bone disease (Ankle and foot)
0.028 0.971 0.000
M83.46 Aluminium bone disease (Lower leg)
0.028 0.971 0.000
M83.45 Aluminium bone disease (Pelvic region and thigh)
0.028 0.971 0.000
M83.44 Aluminium bone disease (Hand)
0.028 0.971 0.000
M83.43 Aluminium bone disease (Forearm)
0.028 0.971 0.000
M83.42 Aluminium bone disease (Upper arm)
0.028 0.971 0.000
M83.41 Aluminium bone disease (Shoulder region)
0.028 0.971 0.000
M83.40 Aluminium bone disease (Multiple sites)
0.028 0.971 0.000
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)
0.028 0.971 0.000
M83.58 Other drug-induced osteomalacia in adults (Other)
0.028 0.971 0.000
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)
0.028 0.971 0.000
M83.56 Other drug-induced osteomalacia in adults (Lower leg)
0.028 0.971 0.000
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)
0.028 0.971 0.000
M83.54 Other drug-induced osteomalacia in adults (Hand)
0.028 0.971 0.000
M83.53 Other drug-induced osteomalacia in adults (Forearm)
0.028 0.971 0.000
M83.52 Other drug-induced osteomalacia in adults (Upper arm)
0.028 0.971 0.000
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)
0.028 0.971 0.000
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)
0.028 0.971 0.000
M83.99 Adult osteomalacia, unspecified (Site unspecified)
0.028 0.971 0.000
M83.98 Adult osteomalacia, unspecified (Other)
0.028 0.971 0.000
M83.97 Adult osteomalacia, unspecified (Ankle and foot)
0.028 0.971 0.000
M83.96 Adult osteomalacia, unspecified (Lower leg)
0.028 0.971 0.000
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)
0.028 0.971 0.000
M83.94 Adult osteomalacia, unspecified (Hand)
0.028 0.971 0.000
M83.93 Adult osteomalacia, unspecified (Forearm)
0.028 0.971 0.000
M83.92 Adult osteomalacia, unspecified (Upper arm)
0.028 0.971 0.000
M83.91 Adult osteomalacia, unspecified (Shoulder region)
0.028 0.971 0.000
M83.90 Adult osteomalacia, unspecified (Multiple sites)
0.028 0.971 0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)
0.028 0.972 0.000
M84.08 Malunion of fracture (Other)
0.028 0.972 0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)
0.028 0.972 0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)
0.028 0.972 0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)
0.028 0.972 0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)
0.028 0.972 0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)
0.028 0.972 0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)
0.028 0.972 0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)
0.028 0.972 0.000
M84.83 Other disorders of continuity of bone (Forearm)
0.028 0.972 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.028 0.972 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.028 0.972 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.028 0.972 0.000
M84.06 Malunion of fracture (Lower leg)
0.027 0.972 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.027 0.973 0.000
M84.09 Malunion of fracture (Site unspecified)
0.027 0.973 0.000
M84.00 Malunion of fracture (Multiple sites)
0.027 0.973 0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)
0.027 0.973 0.000
M84.38 Stress fracture, not elsewhere classified (Other)
0.027 0.973 0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)
0.027 0.973 0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)
0.027 0.973 0.000
M84.34 Stress fracture, not elsewhere classified (Hand)
0.027 0.973 0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)
0.027 0.973 0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)
0.027 0.973 0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)
0.027 0.973 0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)
0.027 0.973 0.000
M83.89 Other adult osteomalacia (Site unspecified)
0.027 0.973 0.000
M83.88 Other adult osteomalacia (Other)
0.027 0.973 0.000
M83.87 Other adult osteomalacia (Ankle and foot)
0.027 0.973 0.000
M83.86 Other adult osteomalacia (Lower leg)
0.027 0.973 0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)
0.027 0.973 0.000
M83.84 Other adult osteomalacia (Hand)
0.027 0.973 0.000
M83.83 Other adult osteomalacia (Forearm)
0.027 0.973 0.000
M83.82 Other adult osteomalacia (Upper arm)
0.027 0.973 0.000
M83.81 Other adult osteomalacia (Shoulder region)
0.027 0.973 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.027 0.973 0.000
M84.05 Malunion of fracture (Pelvic region and thigh)
0.027 0.973 0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)
0.026 0.973 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.026 0.974 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.026 0.974 0.000
C79.2 Secondary malignant neoplasm of skin
0.000 0.974 0.026
M84.89 Other disorders of continuity of bone (Site unspecified)
0.026 0.974 0.000
M84.88 Other disorders of continuity of bone (Other)
0.026 0.974 0.000
M84.86 Other disorders of continuity of bone (Lower leg)
0.026 0.974 0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)
0.026 0.974 0.000
M84.84 Other disorders of continuity of bone (Hand)
0.026 0.974 0.000
M84.82 Other disorders of continuity of bone (Upper arm)
0.026 0.974 0.000
M84.81 Other disorders of continuity of bone (Shoulder region)
0.026 0.974 0.000
M84.80 Other disorders of continuity of bone (Multiple sites)
0.026 0.974 0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.026 0.974 0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)
0.026 0.974 0.000
M84.98 Disorder of continuity of bone, unspecified (Other)
0.026 0.974 0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)
0.026 0.974 0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)
0.026 0.974 0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)
0.026 0.974 0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)
0.026 0.974 0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)
0.026 0.974 0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)
0.026 0.974 0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)
0.026 0.974 0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)
0.026 0.974 0.000
M85.84 Other specified disorders of bone density and structure (Hand)
0.025 0.975 0.000
M85.83 Other specified disorders of bone density and structure (Forearm)
0.025 0.975 0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.025 0.975 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.025 0.975 0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.025 0.975 0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.025 0.975 0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.025 0.975 0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.025 0.975 0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.025 0.975 0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.025 0.975 0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)
0.024 0.975 0.000
M83.80 Other adult osteomalacia (Multiple sites)
0.024 0.975 0.000
M85.0 Fibrous dysplasia (monostotic)
0.024 0.976 0.000
M84.48 Pathological fracture, not elsewhere classified (Other)
0.023 0.976 0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)
0.023 0.976 0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)
0.023 0.976 0.000
M84.29 Delayed union of fracture (Site unspecified)
0.023 0.976 0.000
M84.28 Delayed union of fracture (Other)
0.023 0.976 0.000
M84.27 Delayed union of fracture (Ankle and foot)
0.023 0.976 0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)
0.023 0.976 0.000
M84.24 Delayed union of fracture (Hand)
0.023 0.976 0.000
M84.23 Delayed union of fracture (Forearm)
0.023 0.976 0.000
M84.22 Delayed union of fracture (Upper arm)
0.023 0.976 0.000
M84.21 Delayed union of fracture (Shoulder region)
0.023 0.976 0.000
M84.20 Delayed union of fracture (Multiple sites)
0.023 0.976 0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)
0.023 0.977 0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)
0.023 0.977 0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)
0.023 0.977 0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)
0.023 0.977 0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)
0.023 0.977 0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)
0.023 0.977 0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)
0.023 0.977 0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)
0.023 0.977 0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)
0.023 0.977 0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)
0.023 0.977 0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)
0.023 0.977 0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)
0.023 0.977 0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)
0.023 0.977 0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)
0.023 0.977 0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)
0.023 0.977 0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)
0.023 0.977 0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)
0.023 0.977 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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