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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs541862
log Bayes Factor = 26.9098
Chromosome 6   position 31,916,951  (GRCh37) Explore rs541862 on Ensembl!
Variant rs541862 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.008 0.992
E11 Non-insulin-dependent diabetes mellitus
0.000 0.031 0.969
E65-E68 Obesity and other hyperalimentation
0.000 0.038 0.962
E05.9 Thyrotoxicosis, unspecified
0.000 0.039 0.961
E10.1 With ketoacidosis
0.000 0.047 0.953
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.056 0.944
E11.3 With ophthalmic complications
0.000 0.066 0.934
E66 Obesity
0.000 0.068 0.932
E66.8 Other obesity
0.000 0.072 0.928
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.073 0.927
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.120 0.880
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.133 0.867
E10.5 With peripheral circulatory complications
0.000 0.134 0.866
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.150 0.850
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.159 0.841
E11.9 Without complications
0.000 0.162 0.838
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.196 0.804
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.199 0.801
E11.5 With peripheral circulatory complications
0.000 0.201 0.799
E06 Thyroiditis
0.000 0.210 0.790
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.212 0.788
E10.4 With neurological complications
0.000 0.221 0.779
M06 Other rheumatoid arthritis
0.000 0.228 0.771
E10.2 With renal complications
0.000 0.233 0.767
E11.2 With renal complications
0.000 0.245 0.755
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.286 0.714
E05.5 Thyroid crisis or storm
0.000 0.286 0.714
E05.4 Thyrotoxicosis factitia
0.000 0.286 0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.286 0.714
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.286 0.714
E65 Localised adiposity
0.000 0.287 0.713
E13 Other specified diabetes mellitus
0.000 0.297 0.703
E11.7 With multiple complications
0.000 0.305 0.695
M06.0 Seronegative rheumatoid arthritis
0.000 0.307 0.693
E11.0 With coma
0.000 0.307 0.693
E67 Other hyperalimentation
0.000 0.310 0.689
E68 Sequelae of hyperalimentation
0.000 0.310 0.689
E11.6 With other specified complications
0.000 0.326 0.674
E66.1 Drug-induced obesity
0.000 0.332 0.668
E50-E64 Other nutritional deficiencies
0.000 0.332 0.668
E10.8 With unspecified complications
0.000 0.338 0.662
E06.3 Autoimmune thyroiditis
0.000 0.354 0.646
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.359 0.641
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.359 0.640
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.369 0.630
E66.0 Obesity due to excess calories
0.000 0.371 0.628
E40-E46 Malnutrition
0.000 0.385 0.615
E11.8 With unspecified complications
0.000 0.386 0.614
E11.1 With ketoacidosis
0.000 0.392 0.608
E14 Unspecified diabetes mellitus
0.000 0.393 0.607
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.406 0.594
M06.3 Rheumatoid nodule
0.000 0.412 0.587
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.418 0.582
E06.5 Other chronic thyroiditis
0.000 0.434 0.566
E06.4 Drug-induced thyroiditis
0.000 0.434 0.566
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.434 0.566
E06.1 Subacute thyroiditis
0.000 0.434 0.566
E06.0 Acute thyroiditis
0.000 0.434 0.566
E06.9 Thyroiditis, unspecified
0.000 0.444 0.556
M06.8 Other specified rheumatoid arthritis
0.000 0.447 0.553
M06.2 Rheumatoid bursitis
0.000 0.447 0.553
M06.1 Adult-onset Still's disease
0.000 0.447 0.553
E11.4 With neurological complications
0.000 0.447 0.553
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E13.8 With unspecified complications
0.000 0.496 0.504
E13.7 With multiple complications
0.000 0.496 0.504
E13.6 With other specified complications
0.000 0.496 0.504
E13.5 With peripheral circulatory complications
0.000 0.496 0.504
E13.4 With neurological complications
0.000 0.496 0.504
E13.3 With ophthalmic complications
0.000 0.496 0.504
E13.2 With renal complications
0.000 0.496 0.504
E13.1 With ketoacidosis
0.000 0.496 0.504
E13.0 With coma
0.000 0.496 0.504
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.503 0.497
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.503 0.497
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.503 0.497
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.503 0.497
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.503 0.497
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.503 0.497
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.503 0.497
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.503 0.497
M06.4 Inflammatory polyarthropathy
0.001 0.504 0.495
E67.8 Other specified hyperalimentation
0.000 0.505 0.494
E67.3 Hypervitaminosis D
0.000 0.505 0.494
E67.2 Megavitamin-B6 syndrome
0.000 0.505 0.494
E67.1 Hypercarotenaemia
0.000 0.505 0.494
E67.0 Hypervitaminosis A
0.000 0.505 0.494
E20-E35 Disorders of other endocrine glands
0.000 0.507 0.493
E13.9 Without complications
0.000 0.510 0.490
E03.8 Other specified hypothyroidism
0.001 0.512 0.488
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.521 0.479
E63 Other nutritional deficiencies
0.000 0.521 0.479
E56 Other vitamin deficiencies
0.000 0.521 0.479
E51 Thiamine deficiency
0.000 0.521 0.479
E50 Vitamin A deficiency
0.000 0.521 0.479
E60 Dietary zinc deficiency
0.000 0.521 0.479
E59 Dietary selenium deficiency
0.000 0.521 0.479
E58 Dietary calcium deficiency
0.000 0.521 0.479
E54 Ascorbic acid deficiency
0.000 0.521 0.479
E52 Niacin deficiency [pellagra]
0.000 0.521 0.479
E55 Vitamin D deficiency
0.000 0.525 0.475
E61 Deficiency of other nutrient elements
0.000 0.537 0.463
E15 Nondiabetic hypoglycaemic coma
0.000 0.541 0.459
E07 Other disorders of thyroid
0.000 0.542 0.457
M06.34 Rheumatoid nodule (Hand)
0.000 0.544 0.456
E53 Deficiency of other B group vitamins
0.000 0.547 0.453
E27 Other disorders of adrenal gland
0.000 0.547 0.453
E14.3 With ophthalmic complications
0.000 0.554 0.446
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.559 0.441
E45 Retarded development following protein-energy malnutrition
0.000 0.559 0.441
E43 Unspecified severe protein-energy malnutrition
0.000 0.559 0.441
E42 Marasmic kwashiorkor
0.000 0.559 0.441
E41 Nutritional marasmus
0.000 0.559 0.441
E40 Kwashiorkor
0.000 0.559 0.441
E14.8 With unspecified complications
0.000 0.564 0.436
E14.7 With multiple complications
0.000 0.564 0.436
E14.6 With other specified complications
0.000 0.564 0.436
E14.5 With peripheral circulatory complications
0.000 0.564 0.436
E14.4 With neurological complications
0.000 0.564 0.436
E14.1 With ketoacidosis
0.000 0.564 0.436
E14.0 With coma
0.000 0.564 0.436
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.578 0.421
M06.38 Rheumatoid nodule (Other)
0.000 0.578 0.421
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.578 0.421
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.578 0.421
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.578 0.421
M06.33 Rheumatoid nodule (Forearm)
0.000 0.578 0.421
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.578 0.421
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.578 0.421
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.578 0.421
E27.1 Primary adrenocortical insufficiency
0.000 0.600 0.400
E14.9 Without complications
0.000 0.601 0.399
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.603 0.396
M06.18 Adult-onset Still's disease (Other)
0.000 0.603 0.396
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.603 0.396
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.603 0.396
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.603 0.396
M06.14 Adult-onset Still's disease (Hand)
0.000 0.603 0.396
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.603 0.396
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.603 0.396
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.603 0.396
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.603 0.396
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.603 0.396
M06.28 Rheumatoid bursitis (Other)
0.000 0.603 0.396
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.603 0.396
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.603 0.396
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.603 0.396
M06.24 Rheumatoid bursitis (Hand)
0.000 0.603 0.396
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.603 0.396
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.603 0.396
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.603 0.396
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.603 0.396
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.603 0.396
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.603 0.396
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.603 0.396
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.603 0.396
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.603 0.396
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.603 0.396
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.603 0.396
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.603 0.396
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.603 0.396
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.603 0.396
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.607 0.393
E20 Hypoparathyroidism
0.000 0.613 0.387
E16 Other disorders of pancreatic internal secretion
0.000 0.617 0.383
E27.8 Other specified disorders of adrenal gland
0.000 0.620 0.380
E04 Other non-toxic goitre
0.000 0.627 0.373
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.630 0.370
E14.2 Withrenal complications
0.000 0.639 0.361
M06.48 Inflammatory polyarthropathy (Other)
0.001 0.644 0.355
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.001 0.644 0.355
M06.46 Inflammatory polyarthropathy (Lower leg)
0.001 0.644 0.355
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.001 0.644 0.355
M06.44 Inflammatory polyarthropathy (Hand)
0.001 0.644 0.355
M06.43 Inflammatory polyarthropathy (Forearm)
0.001 0.644 0.355
M06.42 Inflammatory polyarthropathy (Upper arm)
0.001 0.644 0.355
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.001 0.644 0.355
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.001 0.644 0.355
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.646 0.354
E32 Diseases of thymus
0.000 0.646 0.354
E31 Polyglandular dysfunction
0.000 0.646 0.354
E30 Disorders of puberty, not elsewhere classified
0.000 0.646 0.354
E22 Hyperfunction of pituitary gland
0.000 0.647 0.352
M05-M14 Inflammatory polyarthropathies
0.003 0.655 0.342
E50.9 Vitamin A deficiency, unspecified
0.000 0.656 0.343
E50.8 Other manifestations of vitamin A deficiency
0.000 0.656 0.343
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.656 0.343
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.656 0.343
E50.5 Vitamin A deficiency with night blindness
0.000 0.656 0.343
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.656 0.343
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.656 0.343
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.656 0.343
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.656 0.343
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.656 0.343
E51.9 Thiamine deficiency, unspecified
0.000 0.656 0.343
E51.8 Other manifestations of thiamine deficiency
0.000 0.656 0.343
E51.2 Wernicke's encephalopathy
0.000 0.656 0.343
E51.1 Beriberi
0.000 0.656 0.343
E56.9 Vitamin deficiency, unspecified
0.000 0.656 0.343
E56.8 Deficiency of other vitamins
0.000 0.656 0.343
E56.1 Deficiency of vitamin K
0.000 0.656 0.343
E56.0 Deficiency of vitamin E
0.000 0.656 0.343
E63.9 Nutritional deficiency, unspecified
0.000 0.656 0.343
E63.8 Other specified nutritional deficiencies
0.000 0.656 0.343
E63.1 Imbalance of constituents of food intake
0.000 0.656 0.343
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.656 0.343
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.656 0.343
E64.8 Sequelae of other nutritional deficiencies
0.000 0.656 0.343
E64.3 Sequelae of rickets
0.000 0.656 0.343
E64.2 Sequelae of vitamin C deficiency
0.000 0.656 0.343
E64.1 Sequelae of vitamin A deficiency
0.000 0.656 0.343
E64.0 Sequelae of protein-energy malnutrition
0.000 0.656 0.343
E27.2 Addisonian crisis
0.000 0.658 0.342
E55.0 Rickets, active
0.000 0.659 0.341
E46 Unspecified protein-energy malnutrition
0.000 0.660 0.339
E55.9 Vitamin D deficiency, unspecified
0.000 0.663 0.337
E61.9 Deficiency of nutrient element, unspecified
0.000 0.668 0.332
E61.8 Deficiency of other specified nutrient elements
0.000 0.668 0.332
E61.7 Deficiency of multiple nutrient elements
0.000 0.668 0.332
E61.6 Vanadium deficiency
0.000 0.668 0.332
E61.5 Molybdenum deficiency
0.000 0.668 0.332
E61.4 Chromium deficiency
0.000 0.668 0.332
E61.3 Manganese deficiency
0.000 0.668 0.332
E61.2 Magnesium deficiency
0.000 0.668 0.332
E61.0 Copper deficiency
0.000 0.668 0.332
E21.3 Hyperparathyroidism, unspecified
0.000 0.668 0.332
E07.1 Dyshormogenetic goitre
0.000 0.672 0.328
E07.0 Hypersecretion of calcitonin
0.000 0.672 0.328
E53.1 Pyridoxine deficiency
0.000 0.675 0.325
E53.0 Riboflavin deficiency
0.000 0.675 0.325
E27.5 Adrenomedullary hyperfunction
0.000 0.675 0.325
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.675 0.325
E27.0 Other adrenocortical overactivity
0.000 0.675 0.325
L40.9 Psoriasis, unspecified
0.000 0.676 0.324
L40 Psoriasis
0.000 0.677 0.323
L40.5 Arthropathic psoriasis
0.000 0.678 0.322
E28 Ovarian dysfunction
0.000 0.680 0.319
E53.8 Deficiency of other specified B group vitamins
0.000 0.681 0.319
E44.1 Mild protein-energy malnutrition
0.000 0.683 0.316
E44.0 Moderate protein-energy malnutrition
0.000 0.683 0.316
E61.1 Iron deficiency
0.000 0.684 0.316
E20.9 Hypoparathyroidism, unspecified
0.000 0.689 0.311
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.690 0.310
E26 Hyperaldosteronism
0.000 0.692 0.307
E53.9 Vitamin B deficiency, unspecified
0.000 0.694 0.306
M05 Seropositive rheumatoid arthritis
0.002 0.702 0.297
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.001 0.702 0.297
E04.0 Non-toxic diffuse goitre
0.000 0.707 0.293
E25 Adrenogenital disorders
0.001 0.710 0.289
M07 Psoriatic and enteropathic arthropathies
0.002 0.711 0.288
E24 Cushing's syndrome
0.000 0.711 0.289
E07.8 Other specified disorders of thyroid
0.001 0.715 0.284
E22.1 Hyperprolactinaemia
0.000 0.715 0.284
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.718 0.282
E21.4 Other specified disorders of parathyroid gland
0.000 0.718 0.282
E21.2 Other hyperparathyroidism
0.000 0.718 0.282
E29 Testicular dysfunction
0.000 0.719 0.281
E20.8 Other hypoparathyroidism
0.000 0.722 0.278
E20.1 Pseudohypoparathyroidism
0.000 0.722 0.278
E20.0 Idiopathic hypoparathyroidism
0.000 0.722 0.278
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.722 0.278
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.725 0.275
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.725 0.275
E16.4 Abnormal secretion of gastrin
0.000 0.725 0.275
E16.3 Increased secretion of glucagon
0.000 0.725 0.275
L40.0 Psoriasis vulgaris
0.000 0.729 0.271
E04.8 Other specified non-toxic goitre
0.000 0.733 0.267
E04.2 Non-toxic multinodular goitre
0.000 0.733 0.267
E23 Hypofunction and other disorders of pituitary gland
0.000 0.733 0.267
M05.9 Seropositive rheumatoid arthritis, unspecified
0.001 0.735 0.264
E16.1 Other hypoglycaemia
0.000 0.746 0.254
E30.9 Disorder of puberty, unspecified
0.000 0.746 0.254
E30.8 Other disorders of puberty
0.000 0.746 0.254
E30.1 Precocious puberty
0.000 0.746 0.254
E30.0 Delayed puberty
0.000 0.746 0.254
E31.9 Polyglandular dysfunction, unspecified
0.000 0.746 0.254
E31.8 Other polyglandular dysfunction
0.000 0.746 0.254
E31.1 Polyglandular hyperfunction
0.000 0.746 0.254
E31.0 Autoimmune polyglandular failure
0.000 0.746 0.254
E32.9 Disease of thymus, unspecified
0.000 0.746 0.254
E32.8 Other diseases of thymus
0.000 0.746 0.254
E32.1 Abscess of thymus
0.000 0.746 0.254
E32.0 Persistent hyperplasia of thymus
0.000 0.746 0.254
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.746 0.254
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.746 0.254
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.746 0.254
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.747 0.253
E22.8 Other hyperfunction of pituitary gland
0.000 0.747 0.253
M07.3 Other psoriatic arthropathies
0.001 0.751 0.249
M12 Other specific arthropathies
0.003 0.752 0.245
M09 Juvenile arthritis in diseases classified elsewhere
0.003 0.752 0.245
M08 Juvenile arthritis
0.003 0.752 0.245
M14 Arthropathies in other diseases classified elsewhere
0.002 0.756 0.241
L40.8 Other psoriasis
0.000 0.762 0.238
E34 Other endocrine disorders
0.001 0.762 0.237
E22.0 Acromegaly and pituitary gigantism
0.000 0.766 0.233
L40.4 Guttate psoriasis
0.000 0.769 0.231
L40.3 Pustulosis palmaris et plantaris
0.000 0.769 0.231
L40.2 Acrodermatitis continua
0.000 0.769 0.231
L40.1 Generalised pustular psoriasis
0.000 0.769 0.231
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.769 0.230
E27.9 Disorder of adrenal gland, unspecified
0.000 0.769 0.230
E28.9 Ovarian dysfunction, unspecified
0.000 0.771 0.229
E28.8 Other ovarian dysfunction
0.000 0.771 0.229
E28.3 Primary ovarian failure
0.000 0.771 0.229
E28.1 Androgen excess
0.000 0.771 0.229
E28.0 Oestrogen excess
0.000 0.771 0.229
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.771 0.229
M11 Other crystal arthropathies
0.002 0.771 0.226
E16.2 Hypoglycaemia, unspecified
0.000 0.776 0.224
E21.0 Primary hyperparathyroidism
0.000 0.779 0.221
E26.9 Hyperaldosteronism, unspecified
0.000 0.779 0.220
E26.8 Other hyperaldosteronism
0.000 0.779 0.220
E26.1 Secondary hyperaldosteronism
0.000 0.779 0.220
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.780 0.219
M05.8 Other seropositive rheumatoid arthritis
0.001 0.786 0.213
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.001 0.786 0.213
M05.2 Rheumatoid vasculitis
0.001 0.786 0.213
M05.1 Rheumatoid lung disease
0.001 0.786 0.213
M05.0 Felty's syndrome
0.001 0.786 0.213
E25.9 Adrenogenital disorder, unspecified
0.001 0.792 0.208
E25.8 Other adrenogenital disorders
0.001 0.792 0.208
M07.6 Other enteropathic arthropathies
0.001 0.792 0.206
M07.5 Arthropathy in ulcerative colitis
0.001 0.792 0.206
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.001 0.792 0.206
M07.2 Psoriatic spondylitis
0.001 0.792 0.206
M07.1 Arthritis mutilans
0.001 0.792 0.206
M07.0 Distal interphalangeal psoriatic arthropathy
0.001 0.792 0.206
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.792 0.207
E24.8 Other Cushing's syndrome
0.000 0.792 0.207
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.792 0.207
E24.3 Ectopic ACTH syndrome
0.000 0.792 0.207
E24.2 Drug-induced Cushing's syndrome
0.000 0.792 0.207
E24.1 Nelson's syndrome
0.000 0.792 0.207
E24.0 Pituitary-dependent Cushing's disease
0.000 0.792 0.207
E29.9 Testicular dysfunction, unspecified
0.000 0.798 0.201
E29.8 Other testicular dysfunction
0.000 0.798 0.201
E29.0 Testicular hyperfunction
0.000 0.798 0.201
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.798 0.201
M10 Gout
0.002 0.801 0.197
E28.2 Polycystic ovarian syndrome
0.000 0.805 0.195
E23.7 Disorder of pituitary gland, unspecified
0.000 0.807 0.192
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.808 0.191
E23.1 Drug-induced hypopituitarism
0.000 0.808 0.191
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.001 0.810 0.189
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.001 0.810 0.189
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.001 0.810 0.189
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.001 0.810 0.189
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.001 0.810 0.189
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.001 0.810 0.189
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.001 0.810 0.189
E23.2 Diabetes insipidus
0.000 0.814 0.186
L40-L45 Papulosquamous disorders
0.000 0.817 0.183
M07.38 Other psoriatic arthropathies (Other)
0.001 0.821 0.178
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.001 0.821 0.178
M07.36 Other psoriatic arthropathies (Lower leg)
0.001 0.821 0.178
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.001 0.821 0.178
M07.34 Other psoriatic arthropathies (Hand)
0.001 0.821 0.178
M07.33 Other psoriatic arthropathies (Forearm)
0.001 0.821 0.178
M07.32 Other psoriatic arthropathies (Upper arm)
0.001 0.821 0.178
M07.31 Other psoriatic arthropathies (Shoulder region)
0.001 0.821 0.178
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.001 0.821 0.178
M08.9 Juvenile arthritis, unspecified
0.002 0.822 0.176
M08.8 Other juvenile arthritis
0.002 0.822 0.176
M08.4 Pauciarticular juvenile arthritis
0.002 0.822 0.176
M08.3 Juvenile polyarthritis (seronegative)
0.002 0.822 0.176
M08.2 Juvenile arthritis with systemic onset
0.002 0.822 0.176
M08.1 Juvenile ankylosing spondylitis
0.002 0.822 0.176
M08.0 Juvenile rheumatoid arthritis
0.002 0.822 0.176
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.002 0.822 0.176
M09.2 Juvenile arthritis in ulcerative colitis
0.002 0.822 0.176
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.002 0.822 0.176
M09.0 Juvenile arthritis in psoriasis
0.002 0.822 0.176
M12.8 Other specific arthropathies, not elsewhere classified
0.002 0.822 0.176
M12.5 Traumatic arthropathy
0.002 0.822 0.176
M12.4 Intermittent hydrarthrosis
0.002 0.822 0.176
M12.3 Palindromic rheumatism
0.002 0.822 0.176
M12.2 Villonodular synovitis (pigmented)
0.002 0.822 0.176
M12.1 Kaschin-Beck disease
0.002 0.822 0.176
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.002 0.822 0.176
M14.8 Arthropathies in other specified diseases classified elsewhere
0.002 0.825 0.173
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.002 0.825 0.173
M14.4 Arthropathy in amyloidosis
0.002 0.825 0.173
M14.3 Lipoid dermatoarthritis
0.002 0.825 0.173
M14.2 Diabetic arthropathy
0.002 0.825 0.173
M14.1 Crystal arthropathy in other metabolic disorders
0.002 0.825 0.173
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.002 0.825 0.173
E26.0 Primary hyperaldosteronism
0.001 0.825 0.174
E34.5 Androgen resistance syndrome
0.001 0.829 0.170
E34.4 Constitutional tall stature
0.001 0.829 0.170
E34.3 Short stature, not elsewhere classified
0.001 0.829 0.170
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.829 0.170
E34.1 Other hypersecretion of intestinal hormones
0.001 0.829 0.170
M14.6 Neuropathic arthropathy
0.002 0.829 0.169
E23.6 Other disorders of pituitary gland
0.000 0.830 0.170
E07.9 Disorder of thyroid, unspecified
0.001 0.833 0.167
M11.9 Crystal arthropathy, unspecified
0.002 0.836 0.162
M11.8 Other specified crystal arthropathies
0.002 0.836 0.162
M11.1 Familial chondrocalcinosis
0.002 0.836 0.162
M11.0 Hydroxyapatite deposition disease
0.002 0.836 0.162
S61.0 Open wound of finger(s) without damage to nail
0.160 0.840 0.000
M13 Other arthritis
0.001 0.843 0.156
E34.0 Carcinoid syndrome
0.001 0.846 0.154
M05.09 Felty's syndrome (Site unspecified)
0.001 0.846 0.153
M05.08 Felty's syndrome (Other)
0.001 0.846 0.153
M05.07 Felty's syndrome (Ankle and foot)
0.001 0.846 0.153
M05.06 Felty's syndrome (Lower leg)
0.001 0.846 0.153
M05.05 Felty's syndrome (Pelvic region and thigh)
0.001 0.846 0.153
M05.04 Felty's syndrome (Hand)
0.001 0.846 0.153
M05.03 Felty's syndrome (Forearm)
0.001 0.846 0.153
M05.02 Felty's syndrome (Upper arm)
0.001 0.846 0.153
M05.01 Felty's syndrome (Shoulder region)
0.001 0.846 0.153
M05.00 Felty's syndrome (Multiple sites)
0.001 0.846 0.153
M05.19 Rheumatoid lung disease (Site unspecified)
0.001 0.846 0.153
M05.18 Rheumatoid lung disease (Other)
0.001 0.846 0.153
M05.17 Rheumatoid lung disease (Ankle and foot)
0.001 0.846 0.153
M05.16 Rheumatoid lung disease (Lower leg)
0.001 0.846 0.153
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.001 0.846 0.153
M05.14 Rheumatoid lung disease (Hand)
0.001 0.846 0.153
M05.13 Rheumatoid lung disease (Forearm)
0.001 0.846 0.153
M05.12 Rheumatoid lung disease (Upper arm)
0.001 0.846 0.153
M05.11 Rheumatoid lung disease (Shoulder region)
0.001 0.846 0.153
M05.10 Rheumatoid lung disease (Multiple sites)
0.001 0.846 0.153
M05.29 Rheumatoid vasculitis (Site unspecified)
0.001 0.846 0.153
M05.28 Rheumatoid vasculitis (Other)
0.001 0.846 0.153
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.001 0.846 0.153
M05.26 Rheumatoid vasculitis (Lower leg)
0.001 0.846 0.153
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.001 0.846 0.153
M05.24 Rheumatoid vasculitis (Hand)
0.001 0.846 0.153
M05.23 Rheumatoid vasculitis (Forearm)
0.001 0.846 0.153
M05.22 Rheumatoid vasculitis (Upper arm)
0.001 0.846 0.153
M05.21 Rheumatoid vasculitis (Shoulder region)
0.001 0.846 0.153
M05.20 Rheumatoid vasculitis (Multiple sites)
0.001 0.846 0.153
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.001 0.846 0.153
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.001 0.846 0.153
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.001 0.846 0.153
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.001 0.846 0.153
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.001 0.846 0.153
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.001 0.846 0.153
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.001 0.846 0.153
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.001 0.846 0.153
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.001 0.846 0.153
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.001 0.846 0.153
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.001 0.846 0.153
M05.88 Other seropositive rheumatoid arthritis (Other)
0.001 0.846 0.153
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.001 0.846 0.153
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.001 0.846 0.153
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.001 0.846 0.153
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.001 0.846 0.153
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.001 0.846 0.153
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.001 0.846 0.153
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.001 0.846 0.153
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.001 0.846 0.153
E34.8 Other specified endocrine disorders
0.001 0.849 0.150
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.001 0.851 0.148
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.001 0.851 0.148
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.001 0.851 0.148
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.001 0.851 0.148
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.001 0.851 0.148

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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