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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs55791371
log Bayes Factor = 78.5581
Chromosome 19   position 11,188,153  (GRCh37) Explore rs55791371 on Ensembl!
Variant rs55791371 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.000 1.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.000 1.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.001 0.999
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.002 0.998
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.007 0.993
E78.5 Hyperlipidaemia, unspecified
0.000 0.007 0.993
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.012 0.988
I71 Aortic aneurysm and dissection
0.000 0.013 0.987
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.015 0.985
Chapter IX Diseases of the circulatory system
0.000 0.016 0.984
I20.0 Unstable angina
0.000 0.026 0.974
I73 Other peripheral vascular diseases
0.000 0.036 0.964
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.055 0.945
I22 Subsequent myocardial infarction
0.000 0.069 0.931
I05-I09 Chronic rheumatic heart diseases
0.000 0.088 0.912
I21.9 Acute myocardial infarction, unspecified
0.000 0.089 0.911
I73.0 Raynaud's syndrome
0.000 0.099 0.901
I73.9 Peripheral vascular disease, unspecified
0.000 0.100 0.900
I08 Multiple valve diseases
0.000 0.108 0.892
I25.3 Aneurysm of heart
0.000 0.118 0.882
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.132 0.868
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.132 0.868
I24 Other acute ischaemic heart diseases
0.000 0.136 0.864
I20.8 Other forms of angina pectoris
0.000 0.139 0.861
I77 Other disorders of arteries and arterioles
0.000 0.152 0.848
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.153 0.847
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.157 0.843
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.168 0.832
I20.1 Angina pectoris with documented spasm
0.000 0.175 0.825
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.183 0.817
I22.8 Subsequent myocardial infarction of other sites
0.000 0.186 0.814
I77.1 Stricture of artery
0.000 0.217 0.783
E78.8 Other disorders of lipoprotein metabolism
0.000 0.220 0.779
I21.4 Acute subendocardial myocardial infarction
0.000 0.226 0.774
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.231 0.769
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.237 0.763
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.239 0.761
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.250 0.750
I72 Other aneurysm
0.000 0.255 0.745
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.275 0.725
I08.8 Other multiple valve diseases
0.000 0.275 0.725
I25.5 Ischaemic cardiomyopathy
0.000 0.277 0.723
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.288 0.712
E78.3 Hyperchylomicronaemia
0.000 0.288 0.712
I08.0 Disorders of both mitral and aortic valves
0.000 0.290 0.710
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.292 0.708
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.292 0.708
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.292 0.708
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.292 0.708
I00-I02 Acute rheumatic fever
0.000 0.294 0.706
I30-I52 Other forms of heart disease
0.000 0.300 0.700
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.309 0.691
I07 Rheumatic tricuspid valve diseases
0.000 0.309 0.691
I77.0 Arteriovenous fistula, acquired
0.000 0.317 0.683
I74 Arterial embolism and thrombosis
0.000 0.317 0.683
I38 Endocarditis, valve unspecified
0.000 0.320 0.680
Z95.3 Presence of xenogenic heart valve
0.000 0.323 0.677
E78.2 Mixed hyperlipidaemia
0.000 0.327 0.672
I72.4 Aneurysm of artery of lower extremity
0.000 0.331 0.669
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.336 0.664
E78.1 Pure hyperglyceridaemia
0.000 0.338 0.662
I06 Rheumatic aortic valve diseases
0.000 0.346 0.654
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.347 0.653
I73.8 Other specified peripheral vascular diseases
0.000 0.353 0.646
I35 Nonrheumatic aortic valve disorders
0.000 0.354 0.646
I08.9 Multiple valve disease, unspecified
0.000 0.361 0.639
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.362 0.638
E78.4 Other hyperlipidaemia
0.000 0.364 0.636
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.370 0.630
I24.1 Dressler's syndrome
0.000 0.380 0.620
Z95.2 Presence of prosthetic heart valve
0.000 0.384 0.616
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.388 0.612
I25.4 Coronary artery aneurysm
0.000 0.388 0.612
I77.5 Necrosis of artery
0.000 0.392 0.608
I77.4 Coeliac artery compression syndrome
0.000 0.392 0.608
I77.3 Arterial fibromuscular dysplasia
0.000 0.392 0.608
I77.2 Rupture of artery
0.000 0.392 0.608
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.393 0.607
I49 Other cardiac arrhythmias
0.000 0.395 0.605
I70 Atherosclerosis
0.000 0.395 0.605
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.396 0.603
I35.0 Aortic (valve) stenosis
0.000 0.397 0.603
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.399 0.601
I09 Other rheumatic heart diseases
0.000 0.400 0.600
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.412 0.588
I78 Diseases of capillaries
0.000 0.425 0.575
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.435 0.565
I77.8 Other specified disorders of arteries and arterioles
0.000 0.448 0.552
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.452 0.548
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.453 0.547
I79.1 Aortitis in diseases classified elsewhere
0.000 0.453 0.547
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.453 0.547
I30 Acute pericarditis
0.000 0.454 0.546
I49.0 Ventricular fibrillation and flutter
0.000 0.459 0.541
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.465 0.534
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.465 0.534
I72.2 Aneurysm of renal artery
0.000 0.465 0.534
I72.1 Aneurysm of artery of upper extremity
0.000 0.465 0.534
I07.1 Tricuspid insufficiency
0.000 0.468 0.532
I72.3 Aneurysm of iliac artery
0.000 0.479 0.520
I37 Pulmonary valve disorders
0.000 0.482 0.518
Z95.0 Presence of cardiac pacemaker
0.000 0.482 0.518
I74.8 Embolism and thrombosis of other arteries
0.000 0.485 0.515
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.485 0.515
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I99 Other and unspecified disorders of circulatory system
0.000 0.488 0.512
I51 Complications and ill-defined descriptions of heart disease
0.000 0.488 0.512
I72.9 Aneurysm of unspecified site
0.000 0.491 0.509
I02 Rheumatic chorea
0.000 0.494 0.506
I01 Rheumatic fever with heart involvement
0.000 0.494 0.506
I00 Rheumatic fever without mention of heart involvement
0.000 0.494 0.506
I49.8 Other specified cardiac arrhythmias
0.000 0.494 0.506
I52 Other heart disorders in diseases classified elsewhere
0.000 0.498 0.502
I48 Atrial fibrillation and flutter
0.000 0.498 0.502
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.498 0.502
I41 Myocarditis in diseases classified elsewhere
0.000 0.498 0.502
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.498 0.502
I32 Pericarditis in diseases classified elsewhere
0.000 0.498 0.502
I71.0 Dissection of aorta [any part]
0.000 0.500 0.499
I49.9 Cardiac arrhythmia, unspecified
0.000 0.503 0.497
I07.9 Tricuspid valve disease, unspecified
0.000 0.505 0.495
I07.8 Other tricuspid valve diseases
0.000 0.505 0.495
I07.2 Tricuspid stenosis with insufficiency
0.000 0.505 0.495
I07.0 Tricuspid stenosis
0.000 0.505 0.495
I33 Acute and subacute endocarditis
0.000 0.506 0.494
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.506 0.494
I47 Paroxysmal tachycardia
0.000 0.506 0.494
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.509 0.491
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.510 0.489
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.510 0.489
I35.1 Aortic (valve) insufficiency
0.000 0.511 0.489
I45 Other conduction disorders
0.000 0.512 0.488
I44 Atrioventricular and left bundle-branch block
0.000 0.524 0.476
I77.6 Arteritis, unspecified
0.000 0.527 0.473
I40 Acute myocarditis
0.000 0.528 0.472
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.531 0.469
I06.8 Other rheumatic aortic valve diseases
0.000 0.531 0.469
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.531 0.469
I06.1 Rheumatic aortic insufficiency
0.000 0.531 0.469
I06.0 Rheumatic aortic stenosis
0.000 0.531 0.469
I36 Nonrheumatic tricuspid valve disorders
0.000 0.533 0.466
I72.8 Aneurysm of other specified arteries
0.000 0.535 0.465
I49.4 Other and unspecified premature depolarisation
0.000 0.536 0.464
I30.9 Acute pericarditis, unspecified
0.000 0.538 0.462
I95 Hypotension
0.000 0.545 0.455
I28 Other diseases of pulmonary vessels
0.000 0.550 0.450
Z95.4 Presence of other heart-valve replacement
0.000 0.553 0.447
I45.2 Bifascicular block
0.000 0.554 0.446
I72.0 Aneurysm of carotid artery
0.000 0.555 0.445
I35.8 Other aortic valve disorders
0.000 0.555 0.445
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.558 0.442
I49.1 Atrial premature depolarisation
0.000 0.560 0.440
I35.9 Aortic valve disorder, unspecified
0.000 0.562 0.438
I49.2 Junctional premature depolarisation
0.000 0.566 0.434
I70.9 Generalised and unspecified atherosclerosis
0.000 0.566 0.434
I70.8 Atherosclerosis of other arteries
0.000 0.566 0.434
I09.8 Other specified rheumatic heart diseases
0.000 0.570 0.430
I09.2 Chronic rheumatic pericarditis
0.000 0.570 0.430
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.570 0.430
I09.0 Rheumatic myocarditis
0.000 0.570 0.430
I24.8 Other forms of acute ischaemic heart disease
0.000 0.574 0.426
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.574 0.425
I78.8 Other diseases of capillaries
0.000 0.578 0.422
I70.1 Atherosclerosis of renal artery
0.000 0.583 0.417
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.586 0.414
I78.9 Disease of capillaries, unspecified
0.000 0.587 0.413
I51.6 Cardiovascular disease, unspecified
0.000 0.590 0.409
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.596 0.404
I44.7 Left bundle-branch block, unspecified
0.000 0.604 0.396
I51.8 Other ill-defined heart diseases
0.000 0.606 0.394
I74.5 Embolism and thrombosis of iliac artery
0.000 0.606 0.393
I30.8 Other forms of acute pericarditis
0.000 0.609 0.391
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.609 0.391
I95.2 Hypotension due to drugs
0.000 0.609 0.391
I26 Pulmonary embolism
0.000 0.612 0.388
I37.1 Pulmonary valve insufficiency
0.000 0.613 0.387
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.617 0.383
I51.0 Cardiac septal defect, acquired
0.000 0.619 0.381
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.622 0.377
I51.9 Heart disease, unspecified
0.000 0.623 0.377
I09.9 Rheumatic heart disease, unspecified
0.000 0.624 0.376
I27 Other pulmonary heart diseases
0.000 0.626 0.374
I37.9 Pulmonary valve disorder, unspecified
0.000 0.629 0.371
I37.8 Other pulmonary valve disorders
0.000 0.629 0.371
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.629 0.371
I37.0 Pulmonary valve stenosis
0.000 0.629 0.371
I45.9 Conduction disorder, unspecified
0.000 0.630 0.370
I51.5 Myocardial degeneration
0.000 0.633 0.367
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.633 0.367
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.633 0.367
I70.0 Atherosclerosis of aorta
0.000 0.633 0.366
I31 Other diseases of pericardium
0.000 0.636 0.364
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.637 0.363
I01.8 Other acute rheumatic heart disease
0.000 0.637 0.363
I01.2 Acute rheumatic myocarditis
0.000 0.637 0.363
I01.1 Acute rheumatic endocarditis
0.000 0.637 0.363
I01.0 Acute rheumatic pericarditis
0.000 0.637 0.363
I02.9 Rheumatic chorea without heart involvement
0.000 0.637 0.363
I02.0 Rheumatic chorea with heart involvement
0.000 0.637 0.363
I95.1 Orthostatic hypotension
0.000 0.638 0.362
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.640 0.360
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.640 0.360
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.640 0.360
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.640 0.360
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.640 0.360
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.640 0.360
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.640 0.360
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.640 0.360
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.640 0.360
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.640 0.360
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.640 0.360
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.640 0.360
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.640 0.360
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.640 0.360
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.640 0.360
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.640 0.360
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.640 0.360
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.640 0.360
I48.4 Atypical atrial flutter
0.000 0.640 0.360
I48.3 Typical atrial flutter
0.000 0.640 0.360
I48.2 Chronic atrial fibrillation
0.000 0.640 0.360
I48.1 Persistent atrial fibrillation
0.000 0.640 0.360
I48.0 Paroxysmal atrial fibrillation
0.000 0.640 0.360
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.640 0.360
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.640 0.360
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.640 0.360
I33.9 Acute endocarditis, unspecified
0.000 0.646 0.354
I45.0 Right fascicular block
0.000 0.650 0.350
I95.0 Idiopathic hypotension
0.000 0.651 0.349
I47.1 Supraventricular tachycardia
0.000 0.652 0.348
I44.2 Atrioventricular block, complete
0.000 0.652 0.348
I45.8 Other specified conduction disorders
0.000 0.654 0.346
I33.0 Acute and subacute infective endocarditis
0.000 0.654 0.346
I45.1 Other and unspecified right bundle-branch block
0.000 0.655 0.345
I44.5 Left posterior fascicular block
0.000 0.658 0.342
I44.4 Left anterior fascicular block
0.000 0.658 0.342
I30.1 Infective pericarditis
0.000 0.658 0.341
I44.3 Other and unspecified atrioventricular block
0.000 0.659 0.341
I47.2 Ventricular tachycardia
0.000 0.660 0.340
I40.9 Acute myocarditis, unspecified
0.000 0.661 0.339
I40.8 Other acute myocarditis
0.000 0.661 0.339
I40.1 Isolated myocarditis
0.000 0.661 0.339
I28.8 Other specified diseases of pulmonary vessels
0.000 0.662 0.338
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.665 0.334
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.665 0.334
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.665 0.334
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.665 0.334
I51.4 Myocarditis, unspecified
0.000 0.666 0.333
I47.0 Reentry ventricular arrhythmia
0.000 0.668 0.332
I95.8 Other hypotension
0.000 0.671 0.329
I44.6 Other and unspecified fascicular block
0.000 0.673 0.327
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.677 0.323
I28.1 Aneurysm of pulmonary artery
0.000 0.677 0.323
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.677 0.323
I49.3 Ventricular premature depolarisation
0.000 0.679 0.321
I46 Cardiac arrest
0.000 0.680 0.320
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.680 0.320
I78.1 Naevus, nonneoplastic
0.000 0.683 0.317
I44.1 Atrioventricular block, second degree
0.000 0.685 0.315
I27.8 Other specified pulmonary heart diseases
0.000 0.687 0.313
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.689 0.311
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.689 0.311
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.689 0.311
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.689 0.311
I40.0 Infective myocarditis
0.000 0.691 0.309
I45.5 Other specified heart block
0.000 0.692 0.308
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.697 0.303
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.701 0.299
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.701 0.299
I45.6 Preexcitation syndrome
0.000 0.703 0.297
I10-I15 Hypertensive diseases
0.000 0.703 0.297
I45.4 Nonspecific intraventricular block
0.000 0.705 0.294
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.717 0.283
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.717 0.282
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.721 0.278
I27.9 Pulmonary heart disease, unspecified
0.000 0.722 0.278
I45.3 Trifascicular block
0.000 0.726 0.273
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.730 0.270
I27.1 Kyphoscoliotic heart disease
0.000 0.731 0.268
I05 Rheumatic mitral valve diseases
0.001 0.733 0.266
I44.0 Atrioventricular block, first degree
0.000 0.735 0.265
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.737 0.263
I31.8 Other specified diseases of pericardium
0.000 0.739 0.261
I31.2 Haemopericardium, not elsewhere classified
0.000 0.739 0.261
I31.1 Chronic constrictive pericarditis
0.000 0.739 0.261
I31.0 Chronic adhesive pericarditis
0.000 0.739 0.261
I27.2 Other secondary pulmonary hypertension
0.000 0.746 0.254
I31.3 Pericardial effusion (noninflammatory)
0.000 0.747 0.253
I34 Nonrheumatic mitral valve disorders
0.000 0.753 0.247
I15 Secondary hypertension
0.000 0.765 0.235
I46.1 Sudden cardiac death, so described
0.000 0.770 0.230
I49.5 Sick sinus syndrome
0.000 0.770 0.230
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.776 0.224
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.782 0.217
I97.0 Postcardiotomy syndrome
0.000 0.782 0.217
I13 Hypertensive heart and renal disease
0.000 0.787 0.213
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.790 0.210
I70.00 Atherosclerosis of aorta (without gangrene)
0.001 0.804 0.195
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.806 0.193
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.806 0.193
I98.0 Cardiovascular syphilis
0.000 0.806 0.193
I50 Heart failure
0.000 0.807 0.193
I46.9 Cardiac arrest, unspecified
0.000 0.808 0.192
I05.8 Other mitral valve diseases
0.001 0.808 0.191
I15.1 Hypertension secondary to other renal disorders
0.000 0.810 0.190
I51.7 Cardiomegaly
0.000 0.819 0.181
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.822 0.178
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.823 0.177
I05.2 Mitral stenosis with insufficiency
0.001 0.824 0.175
I97.1 Other functional disturbances following cardiac surgery
0.001 0.825 0.174
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.828 0.172
I12 Hypertensive renal disease
0.000 0.828 0.172
I11 Hypertensive heart disease
0.000 0.829 0.171
I15.9 Seconday hypertension, unspecified
0.000 0.831 0.168
I15.8 Other secondary hypertension
0.000 0.831 0.168
I15.2 Hypertension secondary to endocrine disorders
0.000 0.831 0.168
I15.0 Renovascular hypertension
0.000 0.831 0.168
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.832 0.168
I05.0 Mitral stenosis
0.001 0.843 0.156
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.847 0.153
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.847 0.153
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.847 0.153
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.847 0.153
I31.9 Disease of pericardium, unspecified
0.000 0.860 0.140
I34.1 Mitral (valve) prolapse
0.000 0.862 0.138
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.001 0.864 0.135
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.866 0.133
I05.9 Mitral valve disease, unspecified
0.001 0.869 0.130
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.871 0.129
I46.0 Cardiac arrest with successful resuscitation
0.000 0.872 0.128
I50.1 Left ventricular failure
0.000 0.873 0.127
I12.0 Hypertensive renal disease with renal failure
0.000 0.877 0.123
I05.1 Rheumatic mitral insufficiency
0.002 0.877 0.121
I27.0 Primary pulmonary hypertension
0.000 0.904 0.096
I95.9 Hypotension, unspecified
0.000 0.913 0.087
I50.9 Heart failure, unspecified
0.000 0.916 0.084
I12.9 Hypertensive renal disease without renal failure
0.000 0.918 0.081
Y83.2 Surgical operation with anastomosis, bypass or graft
0.000 0.931 0.069
I11.9 Hypertensive heart disease without (congestive) heart failure
0.001 0.932 0.067
I42 Cardiomyopathy
0.001 0.938 0.061
I34.0 Mitral (valve) insufficiency
0.000 0.939 0.061
I42.7 Cardiomyopathy due to drugs and other external agents
0.001 0.955 0.044
I42.5 Other restrictive cardiomyopathy
0.001 0.955 0.044
I42.4 Endocardial fibroelastosis
0.001 0.955 0.044
I42.3 Endomyocardial (eosinophilic) disease
0.001 0.955 0.044
I50.0 Congestive heart failure
0.000 0.958 0.042
I42.8 Other cardiomyopathies
0.001 0.963 0.036
I42.0 Dilated cardiomyopathy
0.000 0.965 0.034
I42.2 Other hypertrophic cardiomyopathy
0.001 0.965 0.034
I42.1 Obstructive hypertrophic cardiomyopathy
0.001 0.967 0.032
I42.6 Alcoholic cardiomyopathy
0.001 0.967 0.032
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.000 0.968 0.032
M13.97 Arthritis, unspecified (Ankle and foot)
0.030 0.970 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.030 0.970 0.000
M13.9 Arthritis, unspecified
0.029 0.971 0.000
I60-I69 Cerebrovascular diseases
0.001 0.972 0.027
M50-M54 Other dorsopathies
0.026 0.974 0.000
M13.93 Arthritis, unspecified (Forearm)
0.026 0.974 0.000
M13.94 Arthritis, unspecified (Hand)
0.025 0.975 0.000
M50 Cervical disk disorders
0.025 0.975 0.000
M50.0 Cervical disk disorder with myelopathy
0.024 0.976 0.000
I62 Other nontraumatic intracranial haemorrhage
0.000 0.976 0.024
M51 Other intervertebral disk disorders
0.024 0.976 0.000
M13 Other arthritis
0.024 0.976 0.000
E70-E90 Metabolic disorders
0.000 0.977 0.023
M45-M49 Spondylopathies
0.023 0.977 0.000
M51.2 Other specified intervertebral disk displacement
0.023 0.977 0.000
M53 Other dorsopathies, not elsewhere classified
0.023 0.977 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.023 0.977 0.000
M54.5 Low back pain
0.023 0.977 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.977 0.023
M47 Spondylosis
0.022 0.977 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.022 0.978 0.000
M47.8 Other spondylosis
0.022 0.978 0.000
M54 Dorsalgia
0.022 0.978 0.000
M48 Other spondylopathies
0.022 0.978 0.000
M05-M14 Inflammatory polyarthropathies
0.022 0.978 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.022 0.978 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.021 0.979 0.000
O80.9 Single spontaneous delivery, unspecified
0.021 0.979 0.000
M54.50 Low back pain (Multiple sites in spine)
0.021 0.979 0.000
M47.86 Other spondylosis (Lumbar region)
0.021 0.979 0.000
M54.56 Low back pain (Lumbar region)
0.021 0.979 0.000
M48.0 Spinal stenosis
0.021 0.979 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.021 0.979 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.979 0.020
E83.5 Disorders of calcium metabolism
0.000 0.980 0.020
M54.57 Low back pain (Lumbosacral region)
0.020 0.980 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.001 0.980 0.020
M47.87 Other spondylosis (Lumbosacral region)
0.020 0.980 0.000
M48.06 Spinal stenosis (Lumbar region)
0.020 0.980 0.000
E85 Amyloidosis
0.000 0.980 0.020
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.020 0.980 0.000
M50.2 Other cervical disk displacement
0.020 0.980 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.019 0.981 0.000
M60-M63 Disorders of muscles
0.019 0.981 0.000
M48.02 Spinal stenosis (Cervical region)
0.019 0.981 0.000
O80.0 Spontaneous vertex delivery
0.019 0.981 0.000
M13.98 Arthritis, unspecified (Other)
0.019 0.981 0.000
M51.8 Other specified intervertebral disk disorders
0.019 0.981 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.019 0.981 0.000
M51.4 Schmorl's nodes
0.018 0.981 0.000
E83 Disorders of mineral metabolism
0.000 0.982 0.018
M50.3 Other cervical disk degeneration
0.018 0.982 0.000
O80 Single spontaneous delivery
0.018 0.982 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.982 0.018
M50.8 Other cervical disk disorders
0.018 0.982 0.000
M40-M43 Deforming dorsopathies
0.018 0.982 0.000
M45 Ankylosing spondylitis
0.018 0.982 0.000
M80-M85 Disorders of bone density and structure
0.018 0.982 0.000
M49 Spondylopathies in diseases classified elsewhere
0.018 0.982 0.000
M47.9 Spondylosis, unspecified
0.018 0.982 0.000
M50.1 Cervical disk disorder with radiculopathy
0.018 0.982 0.000
M86-M90 Other osteopathies
0.018 0.982 0.000
M06 Other rheumatoid arthritis
0.018 0.982 0.000
I62.1 Nontraumatic extradural haemorrhage
0.000 0.982 0.017
M47.1 Other spondylosis with myelopathy
0.017 0.982 0.000
M51.3 Other specified intervertebral disk degeneration
0.017 0.983 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.017 0.983 0.000
M13.1 Monoarthritis, not elsewhere classified
0.017 0.983 0.000
M51.9 Intervertebral disk disorder, unspecified
0.017 0.983 0.000
M13.8 Other specified arthritis
0.017 0.983 0.000
M50.9 Cervical disk disorder, unspecified
0.017 0.983 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.017 0.983 0.000
M54.8 Other dorsalgia
0.017 0.983 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.001 0.983 0.017
M48.5 Collapsed vertebra, not elsewhere classified
0.017 0.983 0.000
M62 Other disorders of muscle
0.017 0.983 0.000
E84 Cystic fibrosis
0.000 0.983 0.017
E79 Disorders of purine and pyrimidine metabolism
0.000 0.983 0.017
E77 Disorders of glycoprotein metabolism
0.000 0.983 0.017
E76 Disorders of glycosaminoglycan metabolism
0.000 0.983 0.017
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.983 0.017
E72 Other disorders of amino-acid metabolism
0.000 0.983 0.017
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.983 0.017
E70 Disorders of aromatic amino-acid metabolism
0.000 0.983 0.017
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.983 0.017
M53.9 Dorsopathy, unspecified
0.017 0.983 0.000
M53.8 Other specified dorsopathies
0.017 0.983 0.000
M53.2 Spinal instabilities
0.017 0.983 0.000
M53.1 Cervicobrachial syndrome
0.017 0.983 0.000
M53.0 Cervicocranial syndrome
0.017 0.983 0.000
M54.6 Pain in thoracic spine
0.017 0.983 0.000
M54.54 Low back pain-Thoracic
0.017 0.983 0.000
M54.53 Low back pain-Cervicothoracic
0.017 0.983 0.000
M54.52 Low back pain-Cervical
0.017 0.983 0.000
M54.51 Low back pain-Occipit-atl-axl
0.017 0.983 0.000
E85.9 Amyloidosis, unspecified
0.000 0.983 0.017
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.983 0.016
M47.0 Anterior spinal and vertebral artery compression syndromes
0.016 0.984 0.000
I42.9 Cardiomyopathy, unspecified
0.001 0.984 0.016
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.016 0.984 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.016 0.984 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.016 0.984 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.016 0.984 0.000
M14 Arthropathies in other diseases classified elsewhere
0.016 0.984 0.000
M54.0 Panniculitis affecting regions of neck and back
0.016 0.984 0.000
M48.9 Spondylopathy, unspecified
0.016 0.984 0.000
M48.8 Other specified spondylopathies
0.016 0.984 0.000
M48.4 Fatigue fracture of vertebra
0.016 0.984 0.000
M48.3 Traumatic spondylopathy
0.016 0.984 0.000
M48.2 Kissing spine
0.016 0.984 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.016 0.984 0.000
M12 Other specific arthropathies
0.016 0.984 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.016 0.984 0.000
M08 Juvenile arthritis
0.016 0.984 0.000
E85.4 Organ-limited amyloidosis
0.000 0.984 0.016
M46 Other inflammatory spondylopathies
0.016 0.984 0.000
M05 Seropositive rheumatoid arthritis
0.016 0.984 0.000
M84 Disorders of continuity of bone
0.015 0.984 0.000
M89 Other disorders of bone
0.015 0.984 0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns
0.015 0.985 0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac
0.015 0.985 0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar
0.015 0.985 0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol
0.015 0.985 0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic
0.015 0.985 0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot
0.015 0.985 0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical
0.015 0.985 0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-
0.015 0.985 0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit
0.015 0.985 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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